메뉴 건너뛰기




Volumn 35, Issue 4-5, 1999, Pages 275-286

An overview of immunomodulatory intervention in rheumatoid arthritis

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; IMMUNOMODULATING AGENT; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; MONOCLONAL ANTIBODY;

EID: 0032807821     PISSN: 16993993     EISSN: 16994019     Source Type: Journal    
DOI: 10.1358/dot.1999.35.4-5.552203     Document Type: Conference Paper
Times cited : (7)

References (76)
  • 1
    • 0024587941 scopus 로고
    • Does aggressive therapy of rheumatoid arthritis affect outcome?
    • Kushner, I. Does aggressive therapy of rheumatoid arthritis affect outcome? J Rheumatol 1989, 16: 1-4.
    • (1989) J Rheumatol , vol.16 , pp. 1-4
    • Kushner, I.1
  • 2
    • 0025355623 scopus 로고
    • Fifty years of antirheumatic therapy: The prognosis of rheumatoid arthritis
    • Wolfe, F. Fifty years of antirheumatic therapy: The prognosis of rheumatoid arthritis. J Rheumatol 1990, 17 (Suppl.): 24-32.
    • (1990) J Rheumatol , vol.17 , Issue.SUPPL. , pp. 24-32
    • Wolfe, F.1
  • 3
    • 0023150139 scopus 로고
    • Long-term treatment of RA with sulphasalazine, gold, or penicillamine: A comparison using life-table methods
    • Situnayake, R., Gringulis, K., McConkey, B. Long-term treatment of RA with sulphasalazine, gold, or penicillamine: A comparison using life-table methods. Ann Rheum Dis 1987, 46: 177-83.
    • (1987) Ann Rheum Dis , vol.46 , pp. 177-183
    • Situnayake, R.1    Gringulis, K.2    McConkey, B.3
  • 4
    • 0025304539 scopus 로고
    • Rheumatoid arthritis: Pathophysiology and implications for therapy
    • Harris, E.D. Rheumatoid arthritis: Pathophysiology and implications for therapy. New Engl J Med 1990, 322: 1277-89.
    • (1990) New Engl J Med , vol.322 , pp. 1277-1289
    • Harris, E.D.1
  • 5
    • 0025070329 scopus 로고
    • Immunogenetic and cellular immune mechanisms in rheumatoid arthritis: Relevance to new therapeutic strategies
    • Kingsley, G., Pitzalis, C., Panayi, G.S. Immunogenetic and cellular immune mechanisms in rheumatoid arthritis: Relevance to new therapeutic strategies. Br J Rheumatol 1990, 29: 58-64.
    • (1990) Br J Rheumatol , vol.29 , pp. 58-64
    • Kingsley, G.1    Pitzalis, C.2    Panayi, G.S.3
  • 6
    • 2642629432 scopus 로고
    • The application of biotechnological advances to the treatment of RA
    • F. Wolfe and T. Pincus (Eds.). Marcel Dekker: New York
    • Kavanaugh, A., Lipsky, P. The application of biotechnological advances to the treatment of RA. In: Rheumatoid Arthritis: Pathogenesis, Assessment, Outcome and Treatment. F. Wolfe and T. Pincus (Eds.). Marcel Dekker: New York 1994, 373-99.
    • (1994) Rheumatoid Arthritis: Pathogenesis, Assessment, Outcome and Treatment , pp. 373-399
    • Kavanaugh, A.1    Lipsky, P.2
  • 7
    • 0029119187 scopus 로고
    • Biologic interventions in rheumatoid arthritis
    • Cush, J.J., Kavanaugh, A.F. Biologic interventions in rheumatoid arthritis. Rheum Dis Clin N Amer 1995, 23: 797-816.
    • (1995) Rheum Dis Clin N Amer , vol.23 , pp. 797-816
    • Cush, J.J.1    Kavanaugh, A.F.2
  • 8
    • 0029025431 scopus 로고
    • Biological therapies: A novel approach to the treatment of autoimmune disease
    • Fox, D.A. Biological therapies: A novel approach to the treatment of autoimmune disease. Am J Med 1995, 99: 82-8.
    • (1995) Am J Med , vol.99 , pp. 82-88
    • Fox, D.A.1
  • 9
    • 0029052944 scopus 로고
    • T- and B-cell-dependent pathways in rheumatoid arthritis
    • Goronzy, J., Weyand, C. T- and B-cell-dependent pathways in rheumatoid arthritis. Curr Opin Rheum 1995, 7: 214-21.
    • (1995) Curr Opin Rheum , vol.7 , pp. 214-221
    • Goronzy, J.1    Weyand, C.2
  • 10
    • 0026752620 scopus 로고
    • The importance of the T-cell in initiating and maintaining the chronic synovitis of rheumatoid arthritis
    • Panayi, G., Lanchbury, J., Kingsley, G. The importance of the T-cell in initiating and maintaining the chronic synovitis of rheumatoid arthritis. Arthritis Rheum 1992, 35: 729-35.
    • (1992) Arthritis Rheum , vol.35 , pp. 729-735
    • Panayi, G.1    Lanchbury, J.2    Kingsley, G.3
  • 11
    • 0030459439 scopus 로고    scopus 로고
    • Shift toward T-lymphocytes with a T-helper 1 cytokine-secretion profile in the joints of patients with rheumatoid arthritis
    • Dolhain, R., van der Heiden, A., ter Haar, N., Breedveld, F., Miltenburg, A. Shift toward T-lymphocytes with a T-helper 1 cytokine-secretion profile in the joints of patients with rheumatoid arthritis. Arthritis Rheum 1996, 29: 1961-9.
    • (1996) Arthritis Rheum , vol.29 , pp. 1961-1969
    • Dolhain, R.1    Van Der Heiden, A.2    Ter Haar, N.3    Breedveld, F.4    Miltenburg, A.5
  • 12
    • 0031445542 scopus 로고    scopus 로고
    • Th1/Th2 cytokine balance in arthritis
    • Miossec, P., van den Berg, W. Th1/Th2 cytokine balance in arthritis. Arthritis Rheum 1997, 40: 2105-15.
    • (1997) Arthritis Rheum , vol.40 , pp. 2105-2115
    • Miossec, P.1    Van Den Berg, W.2
  • 13
    • 0031065210 scopus 로고    scopus 로고
    • Evidence for the role of an altered redox state in hyporesponsiveness of synovial T-cells in rheumatoid arthritis
    • Maurice, M., Nakamura, H., van der Voort, E. et al. Evidence for the role of an altered redox state in hyporesponsiveness of synovial T-cells in rheumatoid arthritis. J Immunol 1997, 158: 1458-65.
    • (1997) J Immunol , vol.158 , pp. 1458-1465
    • Maurice, M.1    Nakamura, H.2    Van Der Voort, E.3
  • 14
    • 0030777295 scopus 로고    scopus 로고
    • Inhibition of T-cell apoptosis in the rheumatoid synovium
    • Salmon, M., Scheel-Toellner, D., Huisson, A., et al. Inhibition of T-cell apoptosis in the rheumatoid synovium. J Clin Invest 1997, 99: 439-46.
    • (1997) J Clin Invest , vol.99 , pp. 439-446
    • Salmon, M.1    Scheel-Toellner, D.2    Huisson, A.3
  • 15
    • 0025348745 scopus 로고
    • How important are T-cells in chronic rheumatoid synovitis?
    • Firestein, G., Zvaifler, N. How important are T-cells in chronic rheumatoid synovitis? Arthritis Rheum 1990, 33: 768-73.
    • (1990) Arthritis Rheum , vol.33 , pp. 768-773
    • Firestein, G.1    Zvaifler, N.2
  • 16
    • 0028227917 scopus 로고
    • Pannus and pannocytes, alternative models of joint destruction in rheumatoid arthritis
    • Zvaifler, N., Firestein, G. Pannus and pannocytes, alternative models of joint destruction in rheumatoid arthritis. Arthritis Rheum 1994, 37: 783-9.
    • (1994) Arthritis Rheum , vol.37 , pp. 783-789
    • Zvaifler, N.1    Firestein, G.2
  • 17
    • 0342578133 scopus 로고    scopus 로고
    • Mononuclear phagocytes and rheumatoid synovitis, mastermind or workhorse in arthritis
    • Burmester, G., Stuhlmüller, B., Keyszer, G., Kinne, R. Mononuclear phagocytes and rheumatoid synovitis, mastermind or workhorse in arthritis. Arthritis Rheum 1997, 40: 5-18.
    • (1997) Arthritis Rheum , vol.40 , pp. 5-18
    • Burmester, G.1    Stuhlmüller, B.2    Keyszer, G.3    Kinne, R.4
  • 18
    • 0027982876 scopus 로고
    • Traffic signals for lymphocyte recirculation and leukocyte emigration: The multistep paradigm
    • Springer, T. Traffic signals for lymphocyte recirculation and leukocyte emigration: The multistep paradigm. Cell 1994, 76: 301-14.
    • (1994) Cell , vol.76 , pp. 301-314
    • Springer, T.1
  • 19
    • 0030791408 scopus 로고    scopus 로고
    • Antiadhesion therapy in rheumatoid arthritis: A review of recent progress
    • Kavanaugh, A. Antiadhesion therapy in rheumatoid arthritis: A review of recent progress. BioDrugs, Clin Immunother 1997, 7: 119-33.
    • (1997) BioDrugs, Clin Immunother , vol.7 , pp. 119-133
    • Kavanaugh, A.1
  • 20
    • 0027968717 scopus 로고
    • The prospect for cytokine-based therapeutic strategies in rheumatoid arthritis
    • Campion, G. The prospect for cytokine-based therapeutic strategies in rheumatoid arthritis. Ann Rheum Dis 1994, 53: 485-7.
    • (1994) Ann Rheum Dis , vol.53 , pp. 485-487
    • Campion, G.1
  • 21
    • 0028328881 scopus 로고
    • Cytokine-regulated proteases in autoimmune disease
    • Opdenakker, G., van Damme, J. Cytokine-regulated proteases in autoimmune disease. Immunol Today 1994, 15: 103-6.
    • (1994) Immunol Today , vol.15 , pp. 103-106
    • Opdenakker, G.1    Van Damme, J.2
  • 22
    • 0030911341 scopus 로고    scopus 로고
    • Chronic tumor necrosis factor alters T-cell responses by attenuating T-cell receptor signaling
    • Cope, A., Liblau, R., Yang, X.-D. et al. Chronic tumor necrosis factor alters T-cell responses by attenuating T-cell receptor signaling. J Exp Med 1997, 185: 1573-84.
    • (1997) J Exp Med , vol.185 , pp. 1573-1584
    • Cope, A.1    Liblau, R.2    Yang, X.-D.3
  • 23
    • 0029878787 scopus 로고    scopus 로고
    • Teetering on the brink of danger
    • Pennisi, E. Teetering on the brink of danger. Science 1996, 271: 1665-7.
    • (1996) Science , vol.271 , pp. 1665-1667
    • Pennisi, E.1
  • 24
    • 44949268312 scopus 로고
    • Is T-cell memory maintained by crossreactive stimulation?
    • Beverley, P. Is T-cell memory maintained by crossreactive stimulation? Immunol Today 1990, 11: 203-5.
    • (1990) Immunol Today , vol.11 , pp. 203-205
    • Beverley, P.1
  • 25
    • 0028064578 scopus 로고
    • Competition for follicular niches excludes self-reactive cells from the recirculating B-cell repertoire
    • Cyster, J., Hartley, S., Goodnow, C. Competition for follicular niches excludes self-reactive cells from the recirculating B-cell repertoire. Nature 1994, 371: 389-95.
    • (1994) Nature , vol.371 , pp. 389-395
    • Cyster, J.1    Hartley, S.2    Goodnow, C.3
  • 26
    • 0027059190 scopus 로고
    • Comparison of indium-111-labeled leukocyte scintigraphy and technetium-99m joint scintigraphy in rheumatoid arthritis and osteoarthritis
    • Uno, K., Suguro, T., Nohira, K. et al. Comparison of indium-111-labeled leukocyte scintigraphy and technetium-99m joint scintigraphy in rheumatoid arthritis and osteoarthritis. Ann Nucl Med 1992, 6: 247-51.
    • (1992) Ann Nucl Med , vol.6 , pp. 247-251
    • Uno, K.1    Suguro, T.2    Nohira, K.3
  • 27
    • 0028235297 scopus 로고
    • New directions for biological therapy in rheumatoid arthritis
    • Elliott, M., Maini, R. New directions for biological therapy in rheumatoid arthritis. Int Arch Allergy Immunol 1994, 104: 112-25.
    • (1994) Int Arch Allergy Immunol , vol.104 , pp. 112-125
    • Elliott, M.1    Maini, R.2
  • 28
    • 0028067008 scopus 로고
    • The immunopathogenesis and regulation of T-cell-mediated demyelinating disease
    • Miller, S., Karpus, W. The immunopathogenesis and regulation of T-cell-mediated demyelinating disease. Immunol Today 1994, 15: 356-61.
    • (1994) Immunol Today , vol.15 , pp. 356-361
    • Miller, S.1    Karpus, W.2
  • 29
    • 0029988924 scopus 로고    scopus 로고
    • Persistence of dominant T-cell clones in synovial tissues during rheumatoid arthritis
    • Alam, A., Lambert, N., Lule, J. et al. Persistence of dominant T-cell clones in synovial tissues during rheumatoid arthritis. J Immunol 1996, 156: 3480-5.
    • (1996) J Immunol , vol.156 , pp. 3480-3485
    • Alam, A.1    Lambert, N.2    Lule, J.3
  • 30
    • 0031573213 scopus 로고    scopus 로고
    • T-cell clonality in synovial fluid of a patient with rheumatoid arthritis
    • Kato, T., Kurokawa, M., Masuko-Hongo, K. et al. T-cell clonality in synovial fluid of a patient with rheumatoid arthritis. J Immunol 1997, 159: 5143-9.
    • (1997) J Immunol , vol.159 , pp. 5143-5149
    • Kato, T.1    Kurokawa, M.2    Masuko-Hongo, K.3
  • 31
    • 9344245755 scopus 로고    scopus 로고
    • Vβ17 T-cell receptor peptide vaccination in rheumatoid arthritis: Results of a phase I dose escalation study
    • Moreland, L., Heck, L., Koopman, W. et al. Vβ17 T-cell receptor peptide vaccination in rheumatoid arthritis: Results of a phase I dose escalation study. J Rheum 1996, 23: 1353-62.
    • (1996) J Rheum , vol.23 , pp. 1353-1362
    • Moreland, L.1    Heck, L.2    Koopman, W.3
  • 32
    • 0030000365 scopus 로고    scopus 로고
    • Treatment of rheumatoid arthritis by immunization with mononuclear white blood cells: Results of a preliminary trial
    • Smith, J., Fort, J. Treatment of rheumatoid arthritis by immunization with mononuclear white blood cells: Results of a preliminary trial. J Rheumatol 1996, 23: 220-5.
    • (1996) J Rheumatol , vol.23 , pp. 220-225
    • Smith, J.1    Fort, J.2
  • 33
    • 0026572313 scopus 로고
    • Class II MHC binding peptides: A feasible treatment for arthritis?
    • Kingsley, G. Class II MHC binding peptides: A feasible treatment for arthritis? Clin Exp Rheumatol 1992, 10: 297-300.
    • (1992) Clin Exp Rheumatol , vol.10 , pp. 297-300
    • Kingsley, G.1
  • 34
    • 0025832191 scopus 로고
    • Treatment of autoimmune diseases with antibodies to class II major histocompatibility complex antigens
    • Vladutiu, A. Treatment of autoimmune diseases with antibodies to class II major histocompatibility complex antigens. Clin Immunol Immunop 1991, 61: 1-17.
    • (1991) Clin Immunol Immunop , vol.61 , pp. 1-17
    • Vladutiu, A.1
  • 35
    • 0028997241 scopus 로고
    • Could HLA-DRβ1*0401 be the protective locus in rheumatoid arthritis?
    • Zanelli, E., Gonzalez-Gay, M., David, C. Could HLA-DRβ1*0401 be the protective locus in rheumatoid arthritis? Immunol Today 1995, 16: 274-8.
    • (1995) Immunol Today , vol.16 , pp. 274-278
    • Zanelli, E.1    Gonzalez-Gay, M.2    David, C.3
  • 36
    • 0030847054 scopus 로고    scopus 로고
    • Oral tolerance: Immune mechanisms and treatment of autoimmune diseases
    • Weiner, H. Oral tolerance: Immune mechanisms and treatment of autoimmune diseases. Immunol Today 1997, 18, 335-42.
    • (1997) Immunol Today , vol.18 , pp. 335-342
    • Weiner, H.1
  • 37
    • 0030042970 scopus 로고    scopus 로고
    • Oral type II collagen treatment in early rheumatoid arthritis
    • Sieper, J., Kary, S., Sörenson, H. et al. Oral type II collagen treatment in early rheumatoid arthritis. Arthritis Rheum 1996, 39: 41-51.
    • (1996) Arthritis Rheum , vol.39 , pp. 41-51
    • Sieper, J.1    Kary, S.2    Sörenson, H.3
  • 38
    • 0030704726 scopus 로고    scopus 로고
    • + T-cell subset inhibits antigen-specific T-cell responses and prevents colitis
    • + T-cell subset inhibits antigen-specific T-cell responses and prevents colitis. Nature 1997, 389: 737-42.
    • (1997) Nature , vol.389 , pp. 737-742
    • Groux, H.1    O'Garra, A.2    Bigler, M.3
  • 39
    • 0029851224 scopus 로고    scopus 로고
    • Costimulatory B7 molecules in the pathogenesis of infectious and autoimmune diseases
    • Reiser, H., Stadecke, M. Costimulatory B7 molecules in the pathogenesis of infectious and autoimmune diseases. New Engl J Med 1996, 335: 1369-77.
    • (1996) New Engl J Med , vol.335 , pp. 1369-1377
    • Reiser, H.1    Stadecke, M.2
  • 40
    • 0031132468 scopus 로고    scopus 로고
    • Effects of blocking B7-1 and B7-2 interactions during a type 2 in vivo immune response
    • Greenwald, R., Lu, P., Halvorson, M. et al. Effects of blocking B7-1 and B7-2 interactions during a type 2 in vivo immune response. J Immunol 1997, 158: 4088-96.
    • (1997) J Immunol , vol.158 , pp. 4088-4096
    • Greenwald, R.1    Lu, P.2    Halvorson, M.3
  • 41
    • 0031253956 scopus 로고    scopus 로고
    • Long-term inhibition of murine lupus by brief simultaneous blockade of the B7/CD28 and CD40/gp39 costimulation pathways
    • Daikh, D., Finck, B., Linsley, P., Hollenbough, D., Wofsy, D. Long-term inhibition of murine lupus by brief simultaneous blockade of the B7/CD28 and CD40/gp39 costimulation pathways. Immunol Today 1997, 159: 3104-8.
    • (1997) Immunol Today , vol.159 , pp. 3104-3108
    • Daikh, D.1    Finck, B.2    Linsley, P.3    Hollenbough, D.4    Wofsy, D.5
  • 42
    • 0030870889 scopus 로고    scopus 로고
    • CD40-CD40 ligand interaction in autoimmune disease
    • Datta, S., Kalled, S. CD40-CD40 ligand interaction in autoimmune disease. Arthritis Rheum 1997, 40: 1735-45.
    • (1997) Arthritis Rheum , vol.40 , pp. 1735-1745
    • Datta, S.1    Kalled, S.2
  • 43
    • 0025980476 scopus 로고
    • Treatment of rheumatoid arthritis with an anti-CD4 monoclonal antibody
    • Horneff, G., Burmester, G.R., Emmrich, F., Kalden, J. Treatment of rheumatoid arthritis with an anti-CD4 monoclonal antibody. Arthritis Rheum 1991, 34: 129-40.
    • (1991) Arthritis Rheum , vol.34 , pp. 129-140
    • Horneff, G.1    Burmester, G.R.2    Emmrich, F.3    Kalden, J.4
  • 44
    • 0027503243 scopus 로고
    • Use of a chimeric monoclonal anti-CD4 antibody in patients with refractory rheumatoid arthritis
    • Moreland, L.W., Bucy, R.P., Tilden, A. et al. Use of a chimeric monoclonal anti-CD4 antibody in patients with refractory rheumatoid arthritis. Arthritis Rheum 1993, 36: 307-15.
    • (1993) Arthritis Rheum , vol.36 , pp. 307-315
    • Moreland, L.W.1    Bucy, R.P.2    Tilden, A.3
  • 45
    • 0029115051 scopus 로고
    • A randomized, double-blind, placebo-controlled study of CD4 monoclonal antibody therapy in early rheumatoid arthritis
    • Van der Lubbe, P.A., Dijkmans, B.A.C., Markusse, H.M., Nässander, U., Breedveld, F.C. A randomized, double-blind, placebo-controlled study of CD4 monoclonal antibody therapy in early rheumatoid arthritis. Arthritis Rheum 1995, 38: 1097-106.
    • (1995) Arthritis Rheum , vol.38 , pp. 1097-1106
    • Van Der Lubbe, P.A.1    Dijkmans, B.A.C.2    Markusse, H.M.3    Nässander, U.4    Breedveld, F.C.5
  • 46
    • 0030926207 scopus 로고    scopus 로고
    • Treatment with depleting CD4 monoclonal antibody results in a preferential loss of circulating naive T-cells but does not affect IFN-γ secreting Th1 cells in human
    • Rep, M., van Oosten, B., Roos, M., Ader, H., Polman, C., van Lier, R. Treatment with depleting CD4 monoclonal antibody results in a preferential loss of circulating naive T-cells but does not affect IFN-γ secreting Th1 cells in human. J Clin Invest 1997, 99: 2225-31.
    • (1997) J Clin Invest , vol.99 , pp. 2225-2231
    • Rep, M.1    Van Oosten, B.2    Roos, M.3    Ader, H.4    Polman, C.5    Van Lier, R.6
  • 47
    • 0031963649 scopus 로고    scopus 로고
    • Cutting edge: T-helper 1 and T-helper 2 cells respond differently to chemokines
    • Siveke, J., Hamann, A. Cutting edge: T-helper 1 and T-helper 2 cells respond differently to chemokines. J Immunol 1998, 160: 550-4.
    • (1998) J Immunol , vol.160 , pp. 550-554
    • Siveke, J.1    Hamann, A.2
  • 48
    • 0030716907 scopus 로고    scopus 로고
    • Oligonucleotide adjuvants for T-helper 1 (Th1)-specific vaccination
    • Carson, D., Raz, E. Oligonucleotide adjuvants for T-helper 1 (Th1)-specific vaccination. J Exp Med 1997, 186: 1621-2.
    • (1997) J Exp Med , vol.186 , pp. 1621-1622
    • Carson, D.1    Raz, E.2
  • 49
    • 0031573618 scopus 로고    scopus 로고
    • Suppression of TNF-α expression, inhibition of Th1 activity, and amelioration of collagen-induced arthritis by rolipram
    • Ross, S., Williams, R., Mason, L. et al. Suppression of TNF-α expression, inhibition of Th1 activity, and amelioration of collagen-induced arthritis by rolipram. J Immunol 1997, 159: 6253-9.
    • (1997) J Immunol , vol.159 , pp. 6253-6259
    • Ross, S.1    Williams, R.2    Mason, L.3
  • 50
    • 0031092708 scopus 로고    scopus 로고
    • Substance P-induced IL-12 production by murine macrophages
    • Kincy-Cain, T., Bost, K. Substance P-induced IL-12 production by murine macrophages. J Immunol 1997, 158: 2334-9.
    • (1997) J Immunol , vol.158 , pp. 2334-2339
    • Kincy-Cain, T.1    Bost, K.2
  • 51
    • 0030953117 scopus 로고    scopus 로고
    • Autologous hemopoietic stem cell transplantation: A possible cure for rheumatoid arthritis?
    • Wicks, I., Cooley, H., Szer, J. Autologous hemopoietic stem cell transplantation: A possible cure for rheumatoid arthritis? Arthritis Rheum 1997, 40: 1005-11.
    • (1997) Arthritis Rheum , vol.40 , pp. 1005-1011
    • Wicks, I.1    Cooley, H.2    Szer, J.3
  • 52
    • 0028861236 scopus 로고
    • Inhibition of the production and effects of interleukin-1 and tumor necrosis factor alpha in rheumatoid arthritis
    • Arend, W.P., Dayer, J.M. Inhibition of the production and effects of interleukin-1 and tumor necrosis factor alpha in rheumatoid arthritis. Arthritis Rheum 1995, 38: 151-60.
    • (1995) Arthritis Rheum , vol.38 , pp. 151-160
    • Arend, W.P.1    Dayer, J.M.2
  • 53
    • 0030803513 scopus 로고    scopus 로고
    • Anticytokine therapy in rheumatoid arthritis
    • Firestein, G., Zvaifler, N. Anticytokine therapy in rheumatoid arthritis. New Engl J Med 1997, 337: 195-7.
    • (1997) New Engl J Med , vol.337 , pp. 195-197
    • Firestein, G.1    Zvaifler, N.2
  • 54
    • 0031569219 scopus 로고    scopus 로고
    • Inhibition of nitric oxide synthase for treatment of experimental autoimmune encephalomyelitis
    • Brenner, T., Brocke, S., Szafer, F. et al. Inhibition of nitric oxide synthase for treatment of experimental autoimmune encephalomyelitis. J Immunol 1997, 158: 2940-6.
    • (1997) J Immunol , vol.158 , pp. 2940-2946
    • Brenner, T.1    Brocke, S.2    Szafer, F.3
  • 55
    • 0030928302 scopus 로고    scopus 로고
    • PAF, a potent proinflammatory mediator, looking for its role in the pathogenesis of joint damage
    • Herrero-Beaumont, G., Egido, J. PAF, a potent proinflammatory mediator, looking for its role in the pathogenesis of joint damage. Ann Rheum Dis 1997, 56: 211-3.
    • (1997) Ann Rheum Dis , vol.56 , pp. 211-213
    • Herrero-Beaumont, G.1    Egido, J.2
  • 56
    • 0027255950 scopus 로고
    • Humanized antibodies
    • Winter, G., Harris, W. Humanized antibodies. Immunol Today 1993, 14: 243-6.
    • (1993) Immunol Today , vol.14 , pp. 243-246
    • Winter, G.1    Harris, W.2
  • 57
    • 0025128987 scopus 로고
    • Immunogenicity of recombinant IL-2 modified by covalent attachment of polyethylene glycol
    • Katre, N. Immunogenicity of recombinant IL-2 modified by covalent attachment of polyethylene glycol. J Immunol 1990, 144: 209-13.
    • (1990) J Immunol , vol.144 , pp. 209-213
    • Katre, N.1
  • 58
    • 0030796064 scopus 로고    scopus 로고
    • Increasing the serum persistence of an IgG fragment by random mutagenesis
    • Ghetie, V., Popov, S., Borvak, J. et al. Increasing the serum persistence of an IgG fragment by random mutagenesis. Nat Biotechnol 1997, 15: 637-40.
    • (1997) Nat Biotechnol , vol.15 , pp. 637-640
    • Ghetie, V.1    Popov, S.2    Borvak, J.3
  • 59
    • 0029844521 scopus 로고    scopus 로고
    • Phage libraries - A new route to clinically useful antibodies
    • Marks, C., Marks, J. Phage libraries - A new route to clinically useful antibodies. New Engl J Med 1996, 335, 730-3.
    • (1996) New Engl J Med , vol.335 , pp. 730-733
    • Marks, C.1    Marks, J.2
  • 60
    • 0028222932 scopus 로고
    • Antigen-specific human antibodies from mice comprising four distinct genetic modifications
    • Lonberg, N., Taylor, L., Harding, F. et al. Antigen-specific human antibodies from mice comprising four distinct genetic modifications. Nature 1994, 368: 856-9.
    • (1994) Nature , vol.368 , pp. 856-859
    • Lonberg, N.1    Taylor, L.2    Harding, F.3
  • 61
    • 0028235475 scopus 로고
    • Production of pharmaceutical proteins from transgenic animals
    • Houdebine, L.-M. Production of pharmaceutical proteins from transgenic animals. J Biotechnol 1994, 34: 269-87.
    • (1994) J Biotechnol , vol.34 , pp. 269-287
    • Houdebine, L.-M.1
  • 62
    • 0031963559 scopus 로고    scopus 로고
    • The bladder as a bioreactor: Urothelium production and secretion of growth hormone into urine
    • Kerr, D., Liang, F., Bondioli, K. et al. The bladder as a bioreactor: Urothelium production and secretion of growth hormone into urine. Nat Biotechnol 1998, 16: 75-9.
    • (1998) Nat Biotechnol , vol.16 , pp. 75-79
    • Kerr, D.1    Liang, F.2    Bondioli, K.3
  • 63
    • 0013511183 scopus 로고    scopus 로고
    • Treatment of rheumatoid arthritis with a recombinant human tumor necrosis factor receptor (p75)-Fc fusion protein
    • Moreland, L., Baumgartner, S., Schiff, M. et al. Treatment of rheumatoid arthritis with a recombinant human tumor necrosis factor receptor (p75)-Fc fusion protein. New Engl J Med 1997, 337: 141-7.
    • (1997) New Engl J Med , vol.337 , pp. 141-147
    • Moreland, L.1    Baumgartner, S.2    Schiff, M.3
  • 64
    • 0030941983 scopus 로고    scopus 로고
    • New methods to mimic nature in high-throughput screening
    • Okun, I., Veerapandian, P. New methods to mimic nature in high-throughput screening. Nat Biotechnol 1997, 15: 287-8.
    • (1997) Nat Biotechnol , vol.15 , pp. 287-288
    • Okun, I.1    Veerapandian, P.2
  • 65
    • 0030999134 scopus 로고    scopus 로고
    • Platelet gpIIb/IIIa antagonists: The first anti-integrin receptor therapeutics
    • Coller, B. Platelet gpIIb/IIIa antagonists: The first anti-integrin receptor therapeutics. J Clin Invest 1997, 99: 1467-71.
    • (1997) J Clin Invest , vol.99 , pp. 1467-1471
    • Coller, B.1
  • 66
    • 0030687562 scopus 로고
    • Structure-based design and characterization of exocyclic peptidomimetics that inhibit TNF-α binding to its receptor
    • Takasaki, W., Kajino, Y., Kajino, K., Murali, R., Greene, M. Structure-based design and characterization of exocyclic peptidomimetics that inhibit TNF-α binding to its receptor. Nat Biotechnol 1007, 15: 1266-70.
    • (1007) Nat Biotechnol , vol.15 , pp. 1266-1270
    • Takasaki, W.1    Kajino, Y.2    Kajino, K.3    Murali, R.4    Greene, M.5
  • 67
    • 0030051756 scopus 로고    scopus 로고
    • Molecular medicine: Antisense-oligonucleotide therapy
    • Ansari, F., McDonnell, W. Molecular medicine: Antisense-oligonucleotide therapy. New Engl J Med 1996, 334: 316-8.
    • (1996) New Engl J Med , vol.334 , pp. 316-318
    • Ansari, F.1    McDonnell, W.2
  • 68
    • 0028220670 scopus 로고
    • Inhibition of endothelial cell adhesion molecule expression with antisense oligonucleotides
    • Bennett, C., Condon, T., Grimm, S., Chan, H., Chiang, M. Inhibition of endothelial cell adhesion molecule expression with antisense oligonucleotides. J Immunol 1994, 152: 3530-40.
    • (1994) J Immunol , vol.152 , pp. 3530-3540
    • Bennett, C.1    Condon, T.2    Grimm, S.3    Chan, H.4    Chiang, M.5
  • 69
    • 0029866569 scopus 로고    scopus 로고
    • Inhibition of endothelial cell activation by adenovirus-mediated expression of IκBα, an inhibitor of the transcription factor NF-κB
    • Wrighton, C., Hofer-Warbinek, R., Moll, T., Eytner, R., Bach, F., de Martin, R. Inhibition of endothelial cell activation by adenovirus-mediated expression of IκBα, an inhibitor of the transcription factor NF-κB. J Exp Med 1996, 183: 1013-22.
    • (1996) J Exp Med , vol.183 , pp. 1013-1022
    • Wrighton, C.1    Hofer-Warbinek, R.2    Moll, T.3    Eytner, R.4    Bach, F.5    De Martin, R.6
  • 70
    • 12644302177 scopus 로고    scopus 로고
    • Immunotargeting of liposomes to activated vascular endothelial cells: A strategy for site-selective delivery in the cardiovascular system
    • Spragg, D., Alford, D., Greferath, R. et al. Immunotargeting of liposomes to activated vascular endothelial cells: A strategy for site-selective delivery in the cardiovascular system. Proc Natl Acad Sci USA, 1997, 94: 8795-800.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 8795-8800
    • Spragg, D.1    Alford, D.2    Greferath, R.3
  • 71
    • 0031466808 scopus 로고    scopus 로고
    • Immunotherapeutic potential of bispecific antibodies
    • van de Winkel, J., Bast, B., de Gast, G. Immunotherapeutic potential of bispecific antibodies. Immunol Today 1997, 18: 562-4.
    • (1997) Immunol Today , vol.18 , pp. 562-564
    • Van De Winkel, J.1    Bast, B.2    De Gast, G.3
  • 72
    • 0031557906 scopus 로고    scopus 로고
    • Out with the jab, in with painless pills
    • Larkin, M. Out with the jab, in with painless pills. Lancet 1997, 349: 1676.
    • (1997) Lancet , vol.349 , pp. 1676
    • Larkin, M.1
  • 73
    • 0028143211 scopus 로고
    • Randomized double-blind comparison of chimeric monoclonal antibody to tumor necrosis factor alpha versus placebo in rheumatoid arthritis
    • Eliot, M., Maini, R., Feldmann, M. et al. Randomized double-blind comparison of chimeric monoclonal antibody to tumor necrosis factor alpha versus placebo in rheumatoid arthritis. Lancet 1994, 344: 1105-9.
    • (1994) Lancet , vol.344 , pp. 1105-1109
    • Eliot, M.1    Maini, R.2    Feldmann, M.3
  • 74
    • 0031665786 scopus 로고    scopus 로고
    • Anti-tumor necrosis factor-α monoclonal antibody therapy for rheumatoid arthritis
    • Kavanaugh, A. Anti-tumor necrosis factor-α monoclonal antibody therapy for rheumatoid arthritis. Rheum Dis Clin North Am 1998, 24: 593-614.
    • (1998) Rheum Dis Clin North Am , vol.24 , pp. 593-614
    • Kavanaugh, A.1
  • 75
    • 0028355977 scopus 로고
    • Treatment of refractory rheumatoid arthritis with a monoclonal antibody to intercellular adhesion molecule-1
    • Kavanaugh, A., Davis, L., Nichols, L., et al. Treatment of refractory rheumatoid arthritis with a monoclonal antibody to intercellular adhesion molecule-1. Arthritis Rheum 1994, 37: 992-9.
    • (1994) Arthritis Rheum , vol.37 , pp. 992-999
    • Kavanaugh, A.1    Davis, L.2    Nichols, L.3
  • 76


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.