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Volumn 183, Issue 3, 1996, Pages 1013-1022

Inhibition of endothelial cell activation by adenovirus-mediated expression of IκBα, an inhibitor of the transcription factor NF-κB

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; TRANSCRIPTION FACTOR INHIBITOR; TRANSCRIPTION FACTOR INHIBITOR IKAPPA BALPHA; UNCLASSIFIED DRUG;

EID: 0029866569     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.183.3.1013     Document Type: Article
Times cited : (230)

References (62)
  • 1
    • 0028174061 scopus 로고
    • Function and activation of NF-κB in the immune system
    • Baeuerle, P.A., and T. Henkel 1994. Function and activation of NF-κB in the immune system. Annu. Rev. Immunol. 12: 141-179.
    • (1994) Annu. Rev. Immunol. , vol.12 , pp. 141-179
    • Baeuerle, P.A.1    Henkel, T.2
  • 2
    • 0026509949 scopus 로고
    • NF-κB and related proteins: Rel/dorsal homologies meet ankyrin-like repeats
    • Blank, V., P. Kourilsky, and A. Israel. 1992. NF-κB and related proteins: Rel/dorsal homologies meet ankyrin-like repeats. TIBS (Trends Biochem. Sci.). 17:136-140.
    • (1992) TIBS (Trends Biochem. Sci.) , vol.17 , pp. 136-140
    • Blank, V.1    Kourilsky, P.2    Israel, A.3
  • 3
    • 0027618650 scopus 로고
    • Regulation of the NF-κB/rel transcription factor and IκB inhibitor system
    • Liou, H.-C., and D. Baltimore. 1993. Regulation of the NF-κB/rel transcription factor and IκB inhibitor system. Curr. Opin. Cell Biol. 5:477-487.
    • (1993) Curr. Opin. Cell Biol. , vol.5 , pp. 477-487
    • Liou, H.-C.1    Baltimore, D.2
  • 6
    • 0026527184 scopus 로고
    • The 65-kDa subunit of human NF-κB functions as a potent transcriptional activator and target for v-Rel-mediated repression
    • Ballard, D.W., E.P. Dixon, N.J. Peffer, H. Bogerd, S. Doerre, B. Stein, and W.C. Greene. 1992. The 65-kDa subunit of human NF-κB functions as a potent transcriptional activator and target for v-Rel-mediated repression. Proc. Natl. Acad. Sci. USA. 89:1875-1879.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 1875-1879
    • Ballard, D.W.1    Dixon, E.P.2    Peffer, N.J.3    Bogerd, H.4    Doerre, S.5    Stein, B.6    Greene, W.C.7
  • 7
    • 0025975795 scopus 로고
    • DNA binding and IkB inhibition of the cloned p65 subuint of NF-κB, a rel-related polypeptide
    • Nolan, G.P., S. Ghosh, H.-C. Liou, P. Tempst, and D. Baltimore. 1991. DNA binding and IkB inhibition of the cloned p65 subuint of NF-κB, a rel-related polypeptide. Cell. 64: 961-969.
    • (1991) Cell , vol.64 , pp. 961-969
    • Nolan, G.P.1    Ghosh, S.2    Liou, H.-C.3    Tempst, P.4    Baltimore, D.5
  • 11
    • 0025149657 scopus 로고
    • Cloning of a mitogen-inducible gene encoding a κB DNA-binding protein with homology to the rel oncogene and to cell-cycle motifs
    • Bours, V., J. Villalobos, P.R. Burd, K. Kelly, and U. Sieben-list. 1990. Cloning of a mitogen-inducible gene encoding a κB DNA-binding protein with homology to the rel oncogene and to cell-cycle motifs. Nature (Lond.). 348:76-80.
    • (1990) Nature (Lond.) , vol.348 , pp. 76-80
    • Bours, V.1    Villalobos, J.2    Burd, P.R.3    Kelly, K.4    Sieben-list, U.5
  • 12
    • 0025078530 scopus 로고
    • Cloning of the p50 DNA binding subunit of NF-κB: Homology to rel and dorsal
    • Ghosh, S., A.M. Gifford, L.R. Riviere, P. Tempst, G P. Nolan, and D. Baltimore. 1990. Cloning of the p50 DNA binding subunit of NF-κB: homology to rel and dorsal. Cell 62: 1019-1029.
    • (1990) Cell , vol.62 , pp. 1019-1029
    • Ghosh, S.1    Gifford, A.M.2    Riviere, L.R.3    Tempst, P.4    Nolan, G.P.5    Baltimore, D.6
  • 15
    • 0026675781 scopus 로고
    • Molecular cloning and characterization of a novel Rel/NF-κB family member displaying structural and functonal homology to NF-κB p50/p105
    • Mercurio, F., J. Didonato, C. Rosette, and M. Karin 1992. Molecular cloning and characterization of a novel Rel/NF-κB family member displaying structural and functonal homology to NF-κB p50/p105. DNA (NY). 7:523-527.
    • (1992) DNA (NY) , vol.7 , pp. 523-527
    • Mercurio, F.1    Didonato, J.2    Rosette, C.3    Karin, M.4
  • 16
    • 0026331456 scopus 로고
    • B cell lymphoma-associated chromosomal translocation involves candidate oncogene lyt-10, homologous to NF-κB p50
    • Neri, A., C.-C. Chang, L. Lombardi, M. Salina, P. Corradini, A. T. Maiolo, R.S.K. Chaganti, and R. Dalla-Favera. 1991. B cell lymphoma-associated chromosomal translocation involves candidate oncogene lyt-10, homologous to NF-κB p50. Cell. 67:1075-1087.
    • (1991) Cell , vol.67 , pp. 1075-1087
    • Neri, A.1    Chang, C.-C.2    Lombardi, L.3    Salina, M.4    Corradini, P.5    Maiolo, A.T.6    Chaganti, R.S.K.7    Dalla-Favera, R.8
  • 17
    • 0025738076 scopus 로고
    • Cloning of an NF-κB subunit which stimulates HIV transcription in synergy with p65
    • Schmid, R.M., N.D. Perkins, C.S. Duckett, P.C. Andrews, and G.J. Nabel. 1991. Cloning of an NF-κB subunit which stimulates HIV transcription in synergy with p65. Nature (Lond.). 352:733-736.
    • (1991) Nature (Lond.) , vol.352 , pp. 733-736
    • Schmid, R.M.1    Perkins, N.D.2    Duckett, C.S.3    Andrews, P.C.4    Nabel, G.J.5
  • 18
    • 0028123062 scopus 로고
    • A set of inducible genes expressed by activated human monocytic and endothelial cells contain κB-like sites that specifically bind c-Rel-p65 heterodimers
    • Parry, G.C.N., and N. Mackman. 1994. A set of inducible genes expressed by activated human monocytic and endothelial cells contain κB-like sites that specifically bind c-Rel-p65 heterodimers. J. Biol. Chem. 269:20823-20825.
    • (1994) J. Biol. Chem. , vol.269 , pp. 20823-20825
    • Parry, G.C.N.1    Mackman, N.2
  • 21
    • 0026725026 scopus 로고
    • Rapid induction in regenerating liver of RL/IF-1 (an IκB that inhibits NF-κB, RelB-p50 and c-Rel-p50) and PHF, a novel κB site-binding complex
    • Tewari, M., P. Dobrzanski, K. Mohn, D.E. Cressman, J.-C. Hsu, R. Bravo, and R. Taub. 1991. Rapid induction in regenerating liver of RL/IF-1 (an IκB that inhibits NF-κB, RelB-p50 and c-Rel-p50) and PHF, a novel κB site-binding complex. Mol. Cell. Biol 12:2898-2908.
    • (1991) Mol. Cell. Biol , vol.12 , pp. 2898-2908
    • Tewari, M.1    Dobrzanski, P.2    Mohn, K.3    Cressman, D.E.4    Hsu, J.-C.5    Bravo, R.6    Taub, R.7
  • 23
    • 0026783210 scopus 로고
    • IκB interacts with the nuclear localization sequences of the subunits of NF-κB: A mechanism for cytoplasmic retention
    • Beg, A.A., S.M. Ruben, R.I. Scheinmann, S. Haskill, C. Rosen, and A.S. Baldwin, Jr. 1992. IκB interacts with the nuclear localization sequences of the subunits of NF-κB: a mechanism for cytoplasmic retention. Genes. & Dev. 6:1899-1913.
    • (1992) Genes. & Dev. , vol.6 , pp. 1899-1913
    • Beg, A.A.1    Ruben, S.M.2    Scheinmann, R.I.3    Haskill, S.4    Rosen, C.5    Baldwin Jr., A.S.6
  • 25
    • 0028986075 scopus 로고
    • Control of IκB-α proteolysis by site-specific, signal-induced phosphorylation
    • Brown, K., S Gerstberger, L. Carlson, G. Franzoso, and U. Siebenlist. 1995. Control of IκB-α proteolysis by site-specific, signal-induced phosphorylation. Science (Wash. DC). 267:1485-1488.
    • (1995) Science (Wash. DC) , vol.267 , pp. 1485-1488
    • Brown, K.1    Gerstberger, S.2    Carlson, L.3    Franzoso, G.4    Siebenlist, U.5
  • 26
  • 27
    • 0027980321 scopus 로고
    • The ubiquitin-proteasome pathway is required for processing the NF-κB1 precurser protein and the activation of NF-κB
    • Palombella, V.J., O.J. Rando, A.L. Goldberg, and T. Maniatis. 1994. The ubiquitin-proteasome pathway is required for processing the NF-κB1 precurser protein and the activation of NF-κB. Cell. 78:773-785.
    • (1994) Cell , vol.78 , pp. 773-785
    • Palombella, V.J.1    Rando, O.J.2    Goldberg, A.L.3    Maniatis, T.4
  • 28
    • 0028148227 scopus 로고
    • A proteasome inhibitor prevents activation of NF-κB and stabilizes a newly phosphorylated form of IκB-α that is still bound to NF-κB
    • Traenckner, E.B.-M., S. Wilk, and P.A. Baeuerle. 1994. A proteasome inhibitor prevents activation of NF-κB and stabilizes a newly phosphorylated form of IκB-α that is still bound to NF-κB. EMBO (Eur. Mol. Biol Organ.) J. 13:5433-5441.
    • (1994) EMBO (Eur. Mol. Biol Organ.) J. , vol.13 , pp. 5433-5441
    • Traenckner, E.B.-M.1    Wilk, S.2    Baeuerle, P.A.3
  • 29
    • 0027168447 scopus 로고
    • NF-κB controls expression of inhibitor IκBα: Evidence for an inducible autoregulatory pathway
    • Sun, S.-C., P.A. Ganchi, D.W. Ballard, and W.C. Greene. 1993 NF-κB controls expression of inhibitor IκBα: evidence for an inducible autoregulatory pathway. Science (Wash. DC). 259:1912-1915.
    • (1993) Science (Wash. DC) , vol.259 , pp. 1912-1915
    • Sun, S.-C.1    Ganchi, P.A.2    Ballard, D.W.3    Greene, W.C.4
  • 30
    • 0027462682 scopus 로고
    • Mutual regulation of the transcriptional activator NF-κB and its inhibitor, IκB-α
    • Brown, K., S. Park, T. Kanno, G. Franzoso, and U. Siebenlist. 1993. Mutual regulation of the transcriptional activator NF-κB and its inhibitor, IκB-α. Proc. Natl. Acad. Sci. USA. 90:2532-2536.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 2532-2536
    • Brown, K.1    Park, S.2    Kanno, T.3    Franzoso, G.4    Siebenlist, U.5
  • 31
    • 0027168948 scopus 로고
    • The p65 subunit of NF-κB regulates IκB by two distinct mechanisms
    • Scott, M.L., T. Fujita, H.-C. Liou, G.P. Nolan, and D. Baltimore. 1993. The p65 subunit of NF-κB regulates IκB by two distinct mechanisms. Genes & Dev. 7:1266-1276.
    • (1993) Genes & Dev. , vol.7 , pp. 1266-1276
    • Scott, M.L.1    Fujita, T.2    Liou, H.-C.3    Nolan, G.P.4    Baltimore, D.5
  • 34
    • 0025304791 scopus 로고
    • Purified human IκB can rapidly dissociate the complex of the NF-κB transcription factor with its cognate DNA
    • Zabel, U., and P.A. Baeuerle. 1990. Purified human IκB can rapidly dissociate the complex of the NF-κB transcription factor with its cognate DNA. Cell. 61:255-265.
    • (1990) Cell , vol.61 , pp. 255-265
    • Zabel, U.1    Baeuerle, P.A.2
  • 35
    • 0001811618 scopus 로고
    • Large vessel endothelial isolation
    • J.B. Warren, editor. Wiley-Liss, Inc., New York
    • Warren, J.B. 1990. Large vessel endothelial isolation. In The Endothelium. J.B. Warren, editor. Wiley-Liss, Inc., New York. 263-272.
    • (1990) The Endothelium , pp. 263-272
    • Warren, J.B.1
  • 36
    • 0026455171 scopus 로고
    • Adenovirus-mediated transfer of the muscle glycogen phosphorylase gene into hepatocytes confers altered regulation of glycogen metabolism
    • Gomex-Foix, A.M., W.S. Coats, S. Baques, T. Alam, R.D. Gerard, and C.B. Newgard. 1992. Adenovirus-mediated transfer of the muscle glycogen phosphorylase gene into hepatocytes confers altered regulation of glycogen metabolism. J. Biol. Chem. 267:25129-25134.
    • (1992) J. Biol. Chem. , vol.267 , pp. 25129-25134
    • Gomex-Foix, A.M.1    Coats, W.S.2    Baques, S.3    Alam, T.4    Gerard, R.D.5    Newgard, C.B.6
  • 37
    • 0023883716 scopus 로고
    • A simple technique for the rescue of early region I mutations into infectious human adenovirus type 5
    • McGrory, W.J., D.S. Bautista, and F.L. Graham. 1988. A simple technique for the rescue of early region I mutations into infectious human adenovirus type 5. Virology. 163:614-617.
    • (1988) Virology , vol.163 , pp. 614-617
    • McGrory, W.J.1    Bautista, D.S.2    Graham, F.L.3
  • 38
    • 0015847039 scopus 로고
    • A new technique for the assay of infectivity of human adenovirus 5 DNA
    • Graham, F.L., and A.J. Van der Eb. 1973. A new technique for the assay of infectivity of human adenovirus 5 DNA. Virology. 52:456-467.
    • (1973) Virology , vol.52 , pp. 456-467
    • Graham, F.L.1    Van Der Eb, A.J.2
  • 39
    • 0018650016 scopus 로고
    • An adenovirus type 5 early gene function regulates expression of other early viral genes
    • Jones, N., and T. Shenk. 1979. An adenovirus type 5 early gene function regulates expression of other early viral genes. Proc. Natl. Acad. Sci. USA. 76:3665-3669.
    • (1979) Proc. Natl. Acad. Sci. USA , vol.76 , pp. 3665-3669
    • Jones, N.1    Shenk, T.2
  • 40
    • 0024519186 scopus 로고
    • Complexity of the primary genetic respons to mitogenic activation of human T cells
    • Zipfel, P.F., S.G. Irving, K. Kelly, and U. Siebenlist. 1989. Complexity of the primary genetic respons to mitogenic activation of human T cells. Mol. Cell. Biol. 9:1041-1048.
    • (1989) Mol. Cell. Biol. , vol.9 , pp. 1041-1048
    • Zipfel, P.F.1    Irving, S.G.2    Kelly, K.3    Siebenlist, U.4
  • 41
    • 0021100690 scopus 로고
    • Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei
    • Dignam, J.D., R.M. Lebovitz, and R.G. Roeder. 1983. Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res. 11:1475-1489.
    • (1983) Nucleic Acids Res. , vol.11 , pp. 1475-1489
    • Dignam, J.D.1    Lebovitz, R.M.2    Roeder, R.G.3
  • 43
    • 0027994051 scopus 로고
    • Selective inhibition of E-selectin, ICAM-1 and VCAM-1 in endothelial cells
    • Stuhlmeier, K., V. Csizmadia, Q. Cheng, H. Winkler, and F.H. Bach. 1994. Selective inhibition of E-selectin, ICAM-1 and VCAM-1 in endothelial cells. Eur. J. Immunol. 24:2186-2190.
    • (1994) Eur. J. Immunol. , vol.24 , pp. 2186-2190
    • Stuhlmeier, K.1    Csizmadia, V.2    Cheng, Q.3    Winkler, H.4    Bach, F.H.5
  • 44
    • 0028179224 scopus 로고
    • NF-κB and IκBα: An inducible autoregulatory system in endothelial activation
    • Read, M.A., M.Z. Whitley, A.M. Williams, and T. Collins. 1994. NF-κB and IκBα: an inducible autoregulatory system in endothelial activation. J. Exp. Med. 179:503-512.
    • (1994) J. Exp. Med. , vol.179 , pp. 503-512
    • Read, M.A.1    Whitley, M.Z.2    Williams, A.M.3    Collins, T.4
  • 45
    • 0027984919 scopus 로고
    • In vivo evaluation of the safty of adenovirus-mediated transfer of the human cystic fibrosis transmembrane conductance regulator cDNA to the lung
    • Yei, S., N. Mittereder, S. Wert, J.A. Whitsett, R.W. Wilmott, and B.C. Trapnell. 1994. In vivo evaluation of the safty of adenovirus-mediated transfer of the human cystic fibrosis transmembrane conductance regulator cDNA to the lung. Human Gene Therapy. 5:731-744.
    • (1994) Human Gene Therapy , vol.5 , pp. 731-744
    • Yei, S.1    Mittereder, N.2    Wert, S.3    Whitsett, J.A.4    Wilmott, R.W.5    Trapnell, B.C.6
  • 46
    • 0025854524 scopus 로고
    • Leucocytes roll on a selectin at physiological flow rates: Distinction from and pre-requisite for adhesion through integrins
    • Lawrence, M.B., and T.A. Springer. 1991. Leucocytes roll on a selectin at physiological flow rates: distinction from and pre-requisite for adhesion through integrins. Cell. 65:859-873.
    • (1991) Cell , vol.65 , pp. 859-873
    • Lawrence, M.B.1    Springer, T.A.2
  • 47
    • 0028220670 scopus 로고
    • Inhibition of endothelial cell adhesion molecule expression with antisense oligonucleotides
    • Bennet, C.F., T.P. Condon, S. Grimm, H. Chan, and M.-Y. Chiang. 1994. Inhibition of endothelial cell adhesion molecule expression with antisense oligonucleotides. J. Immunol. 152:3530-3540.
    • (1994) J. Immunol. , vol.152 , pp. 3530-3540
    • Bennet, C.F.1    Condon, T.P.2    Grimm, S.3    Chan, H.4    Chiang, M.-Y.5
  • 48
    • 0028967819 scopus 로고
    • Inducible nuclear expression of newly synthesized IκBα negatively regulates DNA-binding and transcriptional activities of NF-κB
    • Arenzana-Seisdedos, F., J. Thompson, M.S. Rodriguez, F. Bachelerie, D. Thomas, and R.T. Hay. 1995. Inducible nuclear expression of newly synthesized IκBα negatively regulates DNA-binding and transcriptional activities of NF-κB. Mol. Cell Biol. 15:2689-2696.
    • (1995) Mol. Cell Biol. , vol.15 , pp. 2689-2696
    • Arenzana-Seisdedos, F.1    Thompson, J.2    Rodriguez, M.S.3    Bachelerie, F.4    Thomas, D.5    Hay, R.T.6
  • 49
    • 0027269781 scopus 로고
    • 2 and antioxidants have opposite effects on activation of NF-κB and AP-1 in intact cells: AP-1 as secondary antioxidant-responsive factor
    • 2 and antioxidants have opposite effects on activation of NF-κB and AP-1 in intact cells: AP-1 as secondary antioxidant-responsive factor. EMBO (Eur. Mol. Biol. Organ.) J. 12:2005-2015.
    • (1993) EMBO (Eur. Mol. Biol. Organ.) J. , vol.12 , pp. 2005-2015
    • Meyer, M.1    Schreck, R.2    Baeuerle, P.A.3
  • 50
    • 0025642663 scopus 로고
    • Regulation of gene expression with double-stranded phosphorothionate oligonucleotides
    • Bielinska, A., R.A. Shivdasani, L. Zhang, and G.J. Nabel. 1990. Regulation of gene expression with double-stranded phosphorothionate oligonucleotides. Science (Wash. DC). 250: 997-1000.
    • (1990) Science (Wash. DC) , vol.250 , pp. 997-1000
    • Bielinska, A.1    Shivdasani, R.A.2    Zhang, L.3    Nabel, G.J.4
  • 51
    • 0029006149 scopus 로고
    • Inhibition of nuclear translocation of transcription factor NF-κB by a synthetic peptide containing a cell membrane-permeable motif and nuclear localization sequence
    • Lin, Y.Z., S.Y. Yao, R.A. Veach, T.R. Torgerson, and J. Hawiger. 1995. Inhibition of nuclear translocation of transcription factor NF-κB by a synthetic peptide containing a cell membrane-permeable motif and nuclear localization sequence. J. Biol. Chem. 270:14255-14258.
    • (1995) J. Biol. Chem. , vol.270 , pp. 14255-14258
    • Lin, Y.Z.1    Yao, S.Y.2    Veach, R.A.3    Torgerson, T.R.4    Hawiger, J.5
  • 54
    • 0027272371 scopus 로고
    • Efficient adenoviral-mediated ornithine transcarbamylase expression in deficient mouse and human hepatocytes
    • Morsy, M.A., E.L. Alford, A. Bett, F.L. Graham, and C.T. Caskey. 1993. Efficient adenoviral-mediated ornithine transcarbamylase expression in deficient mouse and human hepatocytes. J. Clin. Invest. 92:1580-1586.
    • (1993) J. Clin. Invest. , vol.92 , pp. 1580-1586
    • Morsy, M.A.1    Alford, E.L.2    Bett, A.3    Graham, F.L.4    Caskey, C.T.5
  • 55
    • 0028274289 scopus 로고
    • Adenovirus-mediated gene transfer of soluble vascular cell adhesion molecule to porcine interposition vein grafts
    • Chen, S.J., J.M. Wilson, and D.W. Muller. 1994. Adenovirus-mediated gene transfer of soluble vascular cell adhesion molecule to porcine interposition vein grafts. Circulation. 89: 1922-1928.
    • (1994) Circulation , vol.89 , pp. 1922-1928
    • Chen, S.J.1    Wilson, J.M.2    Muller, D.W.3
  • 57
    • 0025165359 scopus 로고
    • The role of endothelial cells in inflammation
    • Pober, J.S., and R.S. Cotran. 1990. The role of endothelial cells in inflammation. Transplantation (Baltimore). 50:537-567.
    • (1990) Transplantation (Baltimore) , vol.50 , pp. 537-567
    • Pober, J.S.1    Cotran, R.S.2
  • 58
    • 0028899392 scopus 로고
    • IL-6 release and airway administration of human CFTR. cDNA adenovirus vector
    • McElvaney, N.G., and R.G. Crystal. 1995. IL-6 release and airway administration of human CFTR. cDNA adenovirus vector. Nature Medicine. 1:182-184.
    • (1995) Nature Medicine , vol.1 , pp. 182-184
    • McElvaney, N.G.1    Crystal, R.G.2
  • 59
    • 0026445723 scopus 로고
    • Selectins: Interpreters of cell-specific carbohydrate information during inflammation
    • Lasky, L.A. 1992. Selectins: interpreters of cell-specific carbohydrate information during inflammation. Science (Wash. DC). 258:964-969.
    • (1992) Science (Wash. DC) , vol.258 , pp. 964-969
    • Lasky, L.A.1
  • 60
    • 0026342111 scopus 로고
    • Leucocyte-endothelial cell recognition: Three (or more) steps to specificity and diversity
    • Butcher, E.C. 1991. Leucocyte-endothelial cell recognition: three (or more) steps to specificity and diversity. Cell 67: 1033-1036.
    • (1991) Cell , vol.67 , pp. 1033-1036
    • Butcher, E.C.1
  • 61
    • 0028879819 scopus 로고
    • Role of transcriptional activation of IκBα in mediation of immunosuppression by glucocorticoids
    • Scheinman, R.I., P.C. Cogswell, A.K. Lofquist, and A.S. Baldwin. 1995. Role of transcriptional activation of IκBα in mediation of immunosuppression by glucocorticoids. Science (Wash. DC). 270:283-286.
    • (1995) Science (Wash. DC) , vol.270 , pp. 283-286
    • Scheinman, R.I.1    Cogswell, P.C.2    Lofquist, A.K.3    Baldwin, A.S.4
  • 62
    • 0028867899 scopus 로고
    • Immunosuppression by glucocorticoids: Inhibition of NF-κB activity through induction of IκB synthesis
    • Auphan, N., J.A. DiDonato, C. Rosette, A. Helmberg, and M. Karin. 1995. Immunosuppression by glucocorticoids: inhibition of NF-κB activity through induction of IκB synthesis. Science (Wash. DC). 270:286-290.
    • (1995) Science (Wash. DC) , vol.270 , pp. 286-290
    • Auphan, N.1    DiDonato, J.A.2    Rosette, C.3    Helmberg, A.4    Karin, M.5


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