Persistence of dominant T cell clones in synovial tissues during rheumatoid arthritis

Journal of Immunology

Volumn 156, Issue 9, 1996, Pages 3480-3485

  Alam, Antoine ^a   Lambert, Nathalie ^a   Lulé, Jacqueline ^a   Coppin, Hélène ^a   Mazières, Bernard ^b   De Préval, Claude ^a   Cantaerel, Alain ^a,b  

^a CHU PURPAN   (France)

^b CHU RANGUEIL   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; DNA DETERMINATION; HUMAN; HUMAN CELL; HUMAN TISSUE; LYMPHOCYTE CLONE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RHEUMATOID ARTHRITIS; RNA ANALYSIS; SYNOVIUM; T LYMPHOCYTE;

AMINO ACID SEQUENCE; ARTHRITIS, RHEUMATOID; CLONE CELLS; CONSERVED SEQUENCE; FEMALE; GENE REARRANGEMENT, T-LYMPHOCYTE; HUMANS; MALE; MIDDLE AGED; MOLECULAR SEQUENCE DATA; MULTIGENE FAMILY; OPEN READING FRAMES; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA; SYNOVIAL MEMBRANE; T-LYMPHOCYTES; VALINE;

EID: 0029988924     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (46)

1. Panayi, G. S., J. S. Lanchbury, and G. H. Kingsley. 1992. The importance of the T cell in initiating and maintaining the chronic synovitis of rheumatoid arthritis. Arthritis Rheum. 35:729.
2. Davis, M. M., and P. J. Bjorkman. 1988. T-cell antigen receptor gene and T-cell recognition. Nature 334:395.
3. Howell, M., J. P. Diveley, K. A. Lundeen, A. Esty, S. T. Winters, D. J. Carlo, and S. W. Brostoff. 1992. Limited T cell receptor β-chain heterogeneity among interleukin 2 receptor-positive synovial T cells suggests a role for superantigen in rheumatoid arthritis. Proc. Natl. Acad Sci. USA 88:1092.
4. Alam, A., J. Lulé, N. Lambert, H. Coppin, B. Mazières, C. de Préval, and A. Cantagrel. 1995. Vβ gene use in peripheral blood and multiple synovial membrane during rheumatoid arthritis. Hum. Immunol. 42:331.
5. Williams, W. V., Q. Fang, D. Demarco, J. VonFeldt, R. B. Zurier, and D. B. Weiner. 1992. Restricted heterogeneity of T cell receptor transcripts in rheumatoid synovium. J. Clin. Infest. 90:326.
6. Bucht, A., J. R. Oksenberg, S. Lindblad, A. Gronberg, L. Steinmen, and L, Klareskog. 1992. Characterisation of T cell receptor ab repertoire in synovial tissue from different temporal phases of rheumatoid arthritis. Scand. J. Immunol. 35:159.
7. Jenkins, R. N., A. Nikaein, A. Zimmermann, K. Meek, and P. E. Lipsky. 1993. T cell receptor Vβ gene bias in rheumatoid arthritis. J. Clin. Invest. 92:2688.
8. Sottini, A., L. Imberti, R. Gorla, R. Cattaneo, and D. Primi. 1991. Restricted expression of T cell receptor Vβ but not Vα genes in rheumatoid arthritis. Eur. J. Immunol. 21:461.
9. Lunardi, C., C. Marguerie, and A. K. So. 1992. An altered repertoire of T cell receptor V gene expression by rheumatoid synovial fluid T lymphocytes. Clin. Exp. Immunol. 90:440.
10. Struyk, L., J. T. Kurnick, G. E. Hawes, J. M. van Laar, R. Schipper, J. R. Oksenberg, L. Steinman, R. P. de Vries, F. C. Breedveld, and P. Van den Elsen. 1993. T-cell receptor V-gene usage in synovial fluid lymphocytes of patients with chronic arthritis. Hum. Immunol. 37:237.
11. Paillard, X., S. G. West, J. A. Lafferty, J. R. Clements, J. W. Kappler, P. Marrack, and B. L. Kotzin. 1991. Evidence for the effects of a superantigen in rheumatoid arthritis. Science 253:323.
12. Yamamoto, K., H. Sakoda, T. Nakajima, T. Kato, M. Okubo, M. Dohi, Y. Mizushima, K. Ito, and K. Nishioka. 1992. Accumulation of multiple T cell clonotypes in synovial lesions of patients with rheumatoid arthritis revealed by a novel clonality analysis. Int. Immunol. 4:1219.
13. Arnett, F. C., S. M. Edworthy, D. A. Bloch, D. J. McShane, J. F. Fries, N. S. Cooper, L. A. Healey, S. R., Kaplan, M. H. Liang, H. S. Luthra, T. A. Medsger, Jr., D. M. Mitchell, D. H. Neustadt, R. S. Pinals, J. G. Schaller, J. T. Sharp, R. L. Wilder, and G. G. Hunder. 1988. The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum. 31:315.
14. Obata F., and N. Kashiwagi. 1991. Sequence analyses of the T cell receptors utilized for recognition of HLA class D molecules. In HLA 1991 Proceedings of the 11th International Histocompatibility Workshop and Conference, Vol. 1. K. Tsuji, M. Aizawa, and T. Sasazuki, eds. Yokoma, Japan, pp. 865-901.
15. Toyonoga, B., Y. Yoshikai, V. Vadasz, B. Chin, and T. W. Mak. 1985. Organization and sequences of the diversity, joining and constant region genes of the human T-cell receptor β chain. Proc. Natl. Acad. Sci. USA 82:8624.
16. + clones in juvenile rheumatoid arthritis. Proc. Natl. Acad. Sci. USA 90:11104.
17. Wucherpfennig, K. W., J. Zhang, C. Witek, M. Matsui, Y. Modabber, K. Ota, and D. A. Hafler. 1994. Clonal expansion and persistence of human T cells specific for an immunodominant myelin basic protein peptide. J. Immunol. 152:5581.
18. Oksenberg, L., M. A. Panzara, A. B. Begovich, D. Mitchell, H. A. Erlich, R. S. Murray, R. Shimonkevitz, M. Sherritt, J. Rhorhbard, C. C. A. Bernard, and L. Steinman. 1993. Selection for T-cell receptor Vβ-Dβ-Jβ gene rearrangements with specificity for a myelin basic protein peptide in brain lesions of multiple sclerosis. Nature 362:68.
19. Wang, X., L. Golkar, K. Uyemura, J. D. Ohmen, L. G. Villahermosa, T. T. Fajardo, R. V. Cellona, G. P. Walsh, and R. L. Modlin. 1993. T cells bearing Vβ6 T cell receptors in the cell-mediated immune response to Mycobacterium leprae. J. Immunol. 151:7105.
20. Boittel, B., M. Ermonval, P. Panina-Bordignon, R. A. Mariuzza, A. Lanzavecchia, and O. Acuto. 1992. Preferential Vβ usage and lack of junctional sequence conservation among human T cell receptors specific for tetanus toxin-derived peptide: evidence for dominant role of a germline-encoded V region in antigen//major histocompatibility complex recognition. J. Exp. Med. 175:765.
21. Ferradini, F., A. Mackensen, C. Genevé, J. Bosq, P. Duvillard, M. F. Avril, and T. Hercend. 1993. Analysis of T cell receptor variability from a human regressive melanoma: evidence for in situ T cell clonal expansion. J. Clin. Invest. 91:1183.
22. Lehmann, P. V., T. Forsthuber, A. Miller, and E. E. Sercarz. 1992. Spreading of T cell autoimmunity to cryptic determinant of an antigen. Nature 358:155.
23. Lehmann, P. V., E. E. Sercarz, T. Forsthuber, C. M. Dayan, and G. Gammon. 1993. Determinant spreading and the dynamic of the autoimmune T cell repertoire. Immunol. Today 14:203.
24. Kaufman, D. L., M. Clare-Salzer, J. Tian, T. Forsthuber, G. S. P. Ting, P. Robinson, M. A. Atkinson, E. E. Sercarz, A. J. Tobin, and P. V. Lehman. 1993. Spontaneous loss of T cell tolerance to glutamic acid decarboxylase in murine insulin-dependent diabetes. Nature 366:69.
25. Tisch, R., X. D. Yang, S. M. Singer, R. S. Liblau, L. Fugger, and H. O. McDevitt. 1993. Immune response to glutamic acid decarboxylase correlates with insulitis in non-obese diabetic mice. Nature 366:72.
26. Masuko, K., T. Kato, Y. Ikeda, M. Okubo, Y. Mizushima, K. Nishioka, and K. Yamamoto. 1994. Dynamic changes of accumulated T cell clonotypes during antigenic stimulation in vivo and in vitro. Int. Immunol. 6:1959.
27. Grunwald, J., M. Jeddi-Tehrani, H. Dersimonian, R. Anderson, and H. Wigzel. 1992. A persistent T cell expansion in the peripheral blood of a normal adult male: a new clinical entity. Clin. Exp. Immunol. 89:279.
28. + subset in normal human subjects. J. Immunol. 151: 5762.
29. Posnett, D. N., R. Sinha, S. Kabak, and C. Russo. 1994. Clonal populations of T cells in normal elderly humans: the T cell repertoire equivalent to "benign monoclonal gammapathy." J. Exp. Med. 179:609.
30. + T cells in rheumatoid arthritis. J. Clin. Invest. 94:2068.
31. Londei, M., C. M Savill, A. Verhoef, F. Brennan, Z. A. Leech, V. Duance, R. N. Maini, and M. Feldman. 1988. Persistence of collagen type II-specific T-cell clones in the synovial membrane of patient with rheumatoid arthritis. Proc. Natl. Acad. Sci. USA 86:636.
32. Salvetti, M., G. Ristori, M. D'Amato, C. Buttinelli, M. Falcone, C. Fieschi, H. Wekerle, and C. Pozzilli. 1993. Predominant and stable T cell responses to regions of myelin basic protein can be detected in individual patients with multiple sclerosis. Eur. J. Immunol. 23:1232.
33. Utz, U., J. A. Brooks, H. F. McFarland, R. Martin, and W. E. Biddison. 1994. Heterogeneity of T-cell receptor a-chain complementary-determining region 3 in myelin basic protein-specific T cells increases with severity of multiple sclerosis. Proc. Natl. Acad. Sci. USA 91:5567.
34. Raaphorst, F. M., E. L. Kaijzel, M. J. D. Van Tol, J. M. Vossen, and P. J. Van den Elsen. 1993. Non-random employment of Vβ6 and Jβ gene elements and conserved amino acid profiles in CDR3 regions of human fetal and adult TCR β chain rearrangements. Int. Immunol. 6:1.
35. + cells. J. Exp. Med. 174:989.
36. Maruyama, T., I. Saito, S. Miyake, H. Hashimoto, K. Sato, H. Yagita, K. Okumara, and N. Miyasaka. 1993. A possible role of two hydrophobic amino acids in antigen recognition by synovial T cells in rheumatoid arthritis. Eur. J. Immunol. 23:2059.
37. Li, Y., P. Szabo, and D. N. Posnett. 1991. The genomic structure of human V-beta-6 T cell receptor genes. J. Exp. Med. 174:1537.
38. Jorgensen, J. L., U. Esser, B. Fazekas de St Groth, P. A. Reay, and M. M. Davis. 1992. Mapping T cell receptor-peptide contacts by variant peptide immunisation of single-chain transgenics. Nature 355:224.
39. Courtenay, J. S., M. J. Dallman, A. D. Dyan, M. Martin, and B. Mosedale. 1980. Immunisation against heterologous type II collagen induces arthritis in mice. Nature 283:266.
40. Griffiths, M. M., R. J. Eichwald, J. H. Martin, C. B. Smith, and C. W. Dewitt. 1981. Immunogenetic control of experimental type II collagen-induced arthritis. I. Susceptibility and resistance among inbred strains of rats. Arthritis Rheum. 24:871.
41. Yoo, T., S. Y. Kim, J. M. Stuart, R. A. Floyd, G. A. Olson, M. A. Cremer, and A. H. Kang. 1988. Induction of arthritis in monkeys by immunization with type II collagen. J. Exp. Med. 168:777.
42. Jones, D. B., A. F. W. Coulson, and G. W. Duff. 1993. Sequence homologies between hsp60 and autoantigens. Immunol. Today 14:115.
43. Strober, S., and J. Holoshitz. 1990. Mechanisms of immune injury in rheumatoid arthritis: evidence for the involvement of T cells and heat-shock protein. Immunol. Rev. 118:233.
44. Marchalonis, J. J., H. Kaymaz, F. Dedeoglu, S. F. Schulter, D. E. Yocum, and A. B. Edmundson. 1992. Human autoantibodies reactive with synthetic autoantigens from T-cell receptor β chain. Proc. Natl. Acad. Sci. USA 89:3325.
45. Rowly, M. J., D. J. Williarnson, and I. R. Mackay. 1987. Evidence for a local synthesis of antibodies to denaturated collagen in the synovium in rheumatoid arthritis. Arthritis Rheum. 30:1420.
46. Baboonian, C., P. J. W. Venables, D. G. Williams, R. O. Williams, and R. N. Maini. 1991. Cross reaction of antibodies to a glycine/alanine repeat sequence of Epstein-Barr virus nuclear antigen-1 with collagen, cytokeratin and actin. Ann. Rheum. Dis. 50:772.