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Lee, Y., Terwilliger, R.Z., Duman, R.S. Regulation of corticotropin releasing factor receptor-1 (CRF-R1) and BDNF by morphine withdrawal. 28th Annu Meet Soc Neurosci (Nov 7-12, Los Angeles) 1998, Abst 582.13.
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(1998)
28th Annu Meet Soc Neurosci
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Lee, Y.1
Terwilliger, R.Z.2
Duman, R.S.3
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57
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0344840869
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Chronic treatment with the CRF receptor antagonist CP-154,526 decreases defensive withdrawal but does not alter neuroendocrine responses to an acute stressor
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Nov 7-12, Los Angeles Abst 583.3
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Arborelius, L., Thrivikraman, K.V., Plotsky, P.M. Chronic treatment with the CRF receptor antagonist CP-154,526 decreases defensive withdrawal but does not alter neuroendocrine responses to an acute stressor. 28th Annu Meet Soc Neurosci (Nov 7-12, Los Angeles) 1998, Abst 583.3.
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(1998)
28th Annu Meet Soc Neurosci
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Arborelius, L.1
Thrivikraman, K.V.2
Plotsky, P.M.3
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58
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0344409237
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1 antagonist, CP-154,526, in the Vogel and ultrasonic vocalization (USV) tests
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Nov 7-12, Los Angeles Abst 583.5
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1 antagonist, CP-154,526, in the Vogel and ultrasonic vocalization (USV) tests. 28th Annu Meet Soc Neurosci (Nov 7-12, Los Angeles) 1998, Abst 583.5.
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(1998)
28th Annu Meet Soc Neurosci
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Brocco, M.1
Dekeyne, A.2
Dorey, G.3
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59
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CP-154,526: A potent and selective nonpeptide antagonist of corticotropin-releasing factor receptors
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A nonpeptide corticotropin-releasing factor receptor antagonist attenuates fever and exhibits anxiolytic-like activity
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In vivo and in vitro characterization of antalarmine, a nonpeptide corticotropin-releasing hormone (CRH) receptor antagonist: Suppression of pituitary ACTH release and peripheral inflammation
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Hodge, C.N., Aldrich, P.E., Wasserman Z.R. et al. Corticotropin-releasing hormone receptor antagonists: Framework design and synthesis guided by ligand conformational studies. J Med Chem 1999, 42: 819-32.
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Synthesis, corticotropin-releasing factor receptor binding affinity, and pharmacokinetic properties of triazolo-, imidazo-, and pyrrolopyrimidines and -pyridines
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Chorvat, R.J., Bakthavatchalam, R., Beck, J.P. et al. Synthesis, corticotropin-releasing factor receptor binding affinity, and pharmacokinetic properties of triazolo-, imidazo-, and pyrrolopyrimidines and -pyridines. J Med Chem 1999, 42: 833-48.
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Thiazolo[4,5-d]pyrimidine thiones and -ones as potent corticotropin-releasing hormone (CRH-R1) receptor antagonists
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Aug 23-27, Boston Abst MEDI 136
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Curry, M.A., Beck, J.P., Folmer, B.K. et al. Thiazolo[4,5-d]pyrimidine thiones and -ones as potent corticotropin-releasing hormone (CRH-R1) receptor antagonists. 216th ACS Natl Meet (Aug 23-27, Boston) 1998, Abst MEDI 136.
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216th ACS Natl Meet
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Curry, M.A.1
Beck, J.P.2
Folmer, B.K.3
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69
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Pyrazolo[1,5-a]pyrimidine CRF-1 receptor antagonists
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Wustrow, D.J., Capiris, T., Rubin, R. et al. Pyrazolo[1,5-a]pyrimidine CRF-1 receptor antagonists. Bioorg Med Chem Lett 1998, 8: 2067-70.
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Wustrow, D.J.1
Capiris, T.2
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70
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0344409239
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The non-peptide CRF-R1 antagonist, PD171729, inhibits corticotropin-releasing factor (CRF)-induced norepinephrine release in the cortex of rats
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Nov 7-12, Los Angeles Abst 583.2
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Davis, M.D., Cooke, L.W. The non-peptide CRF-R1 antagonist, PD171729, inhibits corticotropin-releasing factor (CRF)-induced norepinephrine release in the cortex of rats. 28th Annu Meet Soc Neurosci (Nov 7-12, Los Angeles) 1998, Abst 583.2.
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(1998)
28th Annu Meet Soc Neurosci
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Davis, M.D.1
Cooke, L.W.2
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71
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0345703786
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In vitro and in vivo characterization of PD171729, a nonpeptide corticotropin-releasing factor (CRF) receptor antagonist
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Nov 7-12, Los Angeles Abst 234.10
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Pugsley, T., Akunne, H., Zoski, K. et al. In vitro and in vivo characterization of PD171729, a nonpeptide corticotropin-releasing factor (CRF) receptor antagonist. 28th Annu Meet Soc Neurosci (Nov 7-12, Los Angeles) 1998, Abst 234.10.
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(1998)
28th Annu Meet Soc Neurosci
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Pugsley, T.1
Akunne, H.2
Zoski, K.3
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72
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0038405783
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Design and synthesis of NBI-30545 and analogues as potent CPF receptor antagonists
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March 21-25, Anaheim Abst MEDI 002
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Wilcoxen, K., Chen, C., Huang, C. et al. Design and synthesis of NBI-30545 and analogues as potent CPF receptor antagonists. 217th ACS Natl Meet (March 21-25, Anaheim) 1999, Abst MEDI 002.
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(1999)
217th ACS Natl Meet
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Wilcoxen, K.1
Chen, C.2
Huang, C.3
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73
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Pyrazolo-[1,5-a]-pyrimidine CRF antagonists: Synthesis and structure activity relationships
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Aug 23-27, Boston Abst MEDI 135
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Gilligan, P.J., Baldauf, C., Cocuzza, A. et al. Pyrazolo-[1,5-a]-pyrimidine CRF antagonists: Synthesis and structure activity relationships. 216th ACS Natl Meet (Aug 23-27, Boston) 1998, Abst MEDI 135.
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(1998)
216th ACS Natl Meet
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Gilligan, P.J.1
Baldauf, C.2
Cocuzza, A.3
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74
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1 receptor antagonists: Design, synthesis and structure activity relationships
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March 21-25, Anaheim Abst MEDI 107
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1 receptor antagonists: Design, synthesis and structure activity relationships. 217th ACS Natl Meet (March 21-25, Anaheim) 1999, Abst MEDI 107.
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(1999)
217th ACS Natl Meet
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He, L.1
Gilligan, P.J.2
Fitzgerald, L.3
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75
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0344409234
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DMP696: A potent, orally bioavailable pyrazolo-[1,5-a]-s-triazine corticotropin-releasing factor (CRF) antagonist
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March 21-25, Anaheim Abst MEDI 004
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Gilligan, P.J., He, L., Zaczek, R. et al. DMP696: A potent, orally bioavailable pyrazolo-[1,5-a]-s-triazine corticotropin-releasing factor (CRF) antagonist. 217th ACS Natl Meet (March 21-25, Anaheim) 1999, Abst MEDI 004.
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(1999)
217th ACS Natl Meet
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Gilligan, P.J.1
He, L.2
Zaczek, R.3
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77
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0345272227
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Imidazo[4,5-c]pyrazoles: A novel heterocyclic series of corticotropin-releasing hormone (CRF-R1) antagonists
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March 21-25, Anaheim Abst MEDI 001
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Beck, J.R., Tivitmahaisoon, R., Folmer, B.K. et al. Imidazo[4,5-c]pyrazoles: A novel heterocyclic series of corticotropin-releasing hormone (CRF-R1) antagonists. 217th ACS Natl Meet (March 21-25, Anaheim) 1999, Abst MEDI 001.
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(1999)
217th ACS Natl Meet
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Beck, J.R.1
Tivitmahaisoon, R.2
Folmer, B.K.3
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78
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0343434045
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Imidazo[4,5-c]pyrazoles as corticotropin-releasing hormone (CRF-R1) receptor antagonists: Detailed pyrazole SAR and synthesis
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March 21-25, Anaheim Abst MEDI 106
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Beck, J.P., Folmer, B.K. Curry, M.A. et al. Imidazo[4,5-c]pyrazoles as corticotropin-releasing hormone (CRF-R1) receptor antagonists: Detailed pyrazole SAR and synthesis. 217th ACS Natl Meet (March 21-25, Anaheim) 1999, Abst MEDI 106.
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(1999)
217th ACS Natl Meet
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Beck, J.P.1
Folmer, B.K.2
Curry, M.A.3
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79
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0344409230
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N-Aryl aminotriazolopyrimidines as corticotropin-releasing hormone (CRH-R1) antagonists
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March 29-April 2, Dallas Abst MEDI 140
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Beck, J.R., Bakthavatchalam, R., Curry, M.A. et al. N-Aryl aminotriazolopyrimidines as corticotropin-releasing hormone (CRH-R1) antagonists. 215th ACS Natl Meet (March 29-April 2, Dallas) 1998, Abst MEDI 140.
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(1998)
215th ACS Natl Meet
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Beck, J.R.1
Bakthavatchalam, R.2
Curry, M.A.3
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80
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0344409231
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Aryloxytriazolopyridines and -pyrimidines: Potent corticotropin-releasing hormone receptor (CRH1) antagonists. Synthesis and SAR
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March 29-April 2, Dallas Abst MEDI 142
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Rajagopalan, R., Junnier, M.L., Chorvat, R.J. et al. Aryloxytriazolopyridines and -pyrimidines: Potent corticotropin-releasing hormone receptor (CRH1) antagonists. Synthesis and SAR. 215th ACS Natl Meet (March 29-April 2, Dallas) 1998, Abst MEDI 142.
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(1998)
215th ACS Natl Meet
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Rajagopalan, R.1
Junnier, M.L.2
Chorvat, R.J.3
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81
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0344409228
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N-Aryl aminotriazolopyrimidines and -pyridines: Synthesis and evaluation as selective corticotropin-releasing hormone (CRH1) receptor antagonists
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March 29-April 2, Dallas Abst MEDI 143
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Bakthavatchalam, R., Arnold, C.R., Arvanitis, A.G. N-Aryl aminotriazolopyrimidines and -pyridines: Synthesis and evaluation as selective corticotropin-releasing hormone (CRH1) receptor antagonists. 215th ACS Natl Meet (March 29-April 2, Dallas) 1998, Abst MEDI 143.
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(1998)
215th ACS Natl Meet
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Bakthavatchalam, R.1
Arnold, C.R.2
Arvanitis, A.G.3
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82
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0342998494
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Aryland anilino-triazolopyridines as corticotropin-releasing factor (CRF) receptor antagonists
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March 29-April 2, Dallas Abst MEDI 144
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Arvanitis, A.G., Bakthavatchalam, R., Beck, J.P. et al. Aryland anilino-triazolopyridines as corticotropin-releasing factor (CRF) receptor antagonists. 215th ACS Natl Meet (March 29-April 2, Dallas) 1998, Abst MEDI 144.
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(1998)
215th ACS Natl Meet
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Arvanitis, A.G.1
Bakthavatchalam, R.2
Beck, J.P.3
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