Constrained corticotropin-releasing factor antagonists with i-(i + 3) Glu-Lys bridges

Journal of Medicinal Chemistry

Volumn 40, Issue 22, 1997, Pages 3651-3658

  Miranda, Antonio ^b   Lahrichi, Sabine L ^a   Gulyas, Jozsef ^a   Koerber, Steven C ^a   Craig, Anthony G ^a   Corrigan, Anne ^a   Rivier, Catherine ^a   Vale, Wylie ^a   Rivier, Jean ^a  

^a SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

^b FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

CORTICOTROPIN RELEASING FACTOR; GLUTAMINE; LYSINE;

ADRENALECTOMY; ARTICLE; CENTRAL NERVOUS SYSTEM; COMPETITIVE INHIBITION; DRUG EFFICACY; DRUG POTENCY; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; LIGAND BINDING; NONHUMAN; PROTEIN CONFORMATION; RECEPTOR UPREGULATION; STRUCTURE ACTIVITY RELATION;

AMINO ACID SEQUENCE; ANIMALS; CELLS, CULTURED; CORTICOTROPIN-RELEASING HORMONE; GLUTAMIC ACID; HUMANS; LYSINE; MALE; MOLECULAR SEQUENCE DATA; PITUITARY GLAND, ANTERIOR; PROTEIN CONFORMATION; RATS; RATS, SPRAGUE-DAWLEY; SEQUENCE HOMOLOGY, AMINO ACID; SPECTRUM ANALYSIS;

EID: 0030725748     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm970311t     Document Type: Article

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