메뉴 건너뛰기




Volumn 8, Issue 6, 1999, Pages 439-452

Mapping complex traits in diseases of the hair and skin

Author keywords

Complex traits; Gene mapping; Linkage analysis; Linkage disequilibrium; Microarray; Sibpair analysis; Single nucleotide polymorphism

Indexed keywords

ADENOSINE TRIPHOSPHATASE (CALCIUM); COLLAGEN TYPE 7; COMPLEMENTARY DNA; DESMOGLEIN; DESMOPLAKIN; HLA B ANTIGEN; KERATIN; LORICRIN; PLECTIN; PROTEIN GLUTAMINE GAMMA GLUTAMYLTRANSFERASE;

EID: 0032737825     PISSN: 09066705     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1600-0625.1999.tb00302.x     Document Type: Review
Times cited : (14)

References (123)
  • 1
    • 0028090414 scopus 로고
    • Genetic dissection of complex traits
    • Lander E S, Schork N J. Genetic dissection of complex traits. Science 1994: 265: 2037-2048.
    • (1994) Science , vol.265 , pp. 2037-2048
    • Lander, E.S.1    Schork, N.J.2
  • 2
    • 0026345962 scopus 로고
    • Epidermolysis bullosa simplex: Evidence in two families for keratin gene abnormalities
    • Bonifas J M, Rothman A L, Epstein E H Jr. Epidermolysis bullosa simplex: evidence in two families for keratin gene abnormalities. Science 1991: 254: 1202-1205.
    • (1991) Science , vol.254 , pp. 1202-1205
    • Bonifas, J.M.1    Rothman, A.L.2    Epstein E.H., Jr.3
  • 3
    • 0027210982 scopus 로고
    • A missense mutation in type VII collagen in two affected siblings with recessive dystrophic epidermolysis bullosa
    • Christiane A M, Greenspan D S, Hoffman G G et al. A missense mutation in type VII collagen in two affected siblings with recessive dystrophic epidermolysis bullosa. Nat Genet 1993: 4: 62-66.
    • (1993) Nat Genet , vol.4 , pp. 62-66
    • Christiane, A.M.1    Greenspan, D.S.2    Hoffman, G.G.3
  • 4
    • 9444272226 scopus 로고    scopus 로고
    • Loss of plectin causes epidermolysis bullosa with muscular dystrophy: CDNA cloning and genomic organization
    • McLean W H I, Pulkkinen L, Smith F J D et al. Loss of plectin causes epidermolysis bullosa with muscular dystrophy: cDNA cloning and genomic organization. Genes Dev 1996: 10: 1724-1735.
    • (1996) Genes Dev , vol.10 , pp. 1724-1735
    • McLean, W.H.I.1    Pulkkinen, L.2    Smith, F.J.D.3
  • 5
    • 84984774604 scopus 로고    scopus 로고
    • Mutations in the plakophilin 1 gene result in ectodermal dysplasia/skin fragility syndrome
    • McGrath J A, McMillan J R, Shemanko C S et al. Mutations in the plakophilin 1 gene result in ectodermal dysplasia/skin fragility syndrome. Nat Genet 1997: 17: 240-244.
    • (1997) Nat Genet , vol.17 , pp. 240-244
    • McGrath, J.A.1    McMillan, J.R.2    Shemanko, C.S.3
  • 6
    • 0032930569 scopus 로고    scopus 로고
    • Haploinsufficiency of desmoplakin causes a striate subtype of palmoplantar keratoderma
    • Keith D, Armstrong B, McKenna K E et al. Haploinsufficiency of desmoplakin causes a striate subtype of palmoplantar keratoderma. Hum Molec Genet 1999: 8: 143-148.
    • (1999) Hum Molec Genet , vol.8 , pp. 143-148
    • Keith, D.1    Armstrong, B.2    McKenna, K.E.3
  • 7
    • 0032970153 scopus 로고    scopus 로고
    • N-terminal deletion in a desmosomal cadherin causes the autosomal dominant skin disease striate palmoplantar keratoderma
    • Rickman L, Simrak D, Stevens H P et al. N-terminal deletion in a desmosomal cadherin causes the autosomal dominant skin disease striate palmoplantar keratoderma. Hum Molec Genet 1999: 8: 971-976.
    • (1999) Hum Molec Genet , vol.8 , pp. 971-976
    • Rickman, L.1    Simrak, D.2    Stevens, H.P.3
  • 8
    • 15844391073 scopus 로고    scopus 로고
    • A molecular defect in loricrin, the major component of the cornified cell envelope, underlies Vohwinkel's syndrome
    • Maestrini E, Monaco A P, McGrath J A et al. A molecular defect in loricrin, the major component of the cornified cell envelope, underlies Vohwinkel's syndrome. Nat Genet 1996: 13: 70-77.
    • (1996) Nat Genet , vol.13 , pp. 70-77
    • Maestrini, E.1    Monaco, A.P.2    McGrath, J.A.3
  • 9
    • 0028947560 scopus 로고
    • Mutations of keratinocyte transglutaminase in lamellar ichthyosis
    • Huber M, Rettler I, Bernasconi K et al. Mutations of keratinocyte transglutaminase in lamellar ichthyosis. Science 1995: 267: 525-528.
    • (1995) Science , vol.267 , pp. 525-528
    • Huber, M.1    Rettler, I.2    Bernasconi, K.3
  • 11
    • 0030024088 scopus 로고    scopus 로고
    • Mutations in the protoporphyrinogen oxidase gene in patients with variegate porphyria
    • Deyback J-C, Puy H, Robreau A-M et al. Mutations in the protoporphyrinogen oxidase gene in patients with variegate porphyria. Hum Molec Genet 1996: 5: 407-410.
    • (1996) Hum Molec Genet , vol.5 , pp. 407-410
    • Deyback, J.-C.1    Puy, H.2    Robreau, A.-M.3
  • 12
    • 15444352074 scopus 로고    scopus 로고
    • Methods for precise sizing, automated binning of alleles, and reduction of error rates in large-scale genotyping using fluorescently labeled dinucleotide markers
    • Ghosh S, Karanjawala Z E, Hauser E R et al. Methods for precise sizing, automated binning of alleles, and reduction of error rates in large-scale genotyping using fluorescently labeled dinucleotide markers. Genome Meth 1997: 7: 165-178.
    • (1997) Genome Meth , vol.7 , pp. 165-178
    • Ghosh, S.1    Karanjawala, Z.E.2    Hauser, E.R.3
  • 13
    • 0032899712 scopus 로고    scopus 로고
    • A full genome scan for late onset Alzheimer's disease
    • Kehoe P, Wavrant-De Vrieze F, Crook R et al. A full genome scan for late onset Alzheimer's disease. Hum Molec Genet 1999: 8: 237-245.
    • (1999) Hum Molec Genet , vol.8 , pp. 237-245
    • Kehoe, P.1    Wavrant-De Vrieze, F.2    Crook, R.3
  • 14
    • 16044372682 scopus 로고    scopus 로고
    • A genome-wide search for quantitative trait loci underlying asthma
    • Daniels S E, Bhattacharrya S, James A et al. A genome-wide search for quantitative trait loci underlying asthma. Nature 1996: 383: 247-250.
    • (1996) Nature , vol.383 , pp. 247-250
    • Daniels, S.1    Bhattacharrya, S.2    James, A.3
  • 15
    • 0030903861 scopus 로고    scopus 로고
    • A genome-wide search for asthma susceptibility loci in ethnically diverse populations
    • The Collaborative Study on the Genetics of Asthma. A genome-wide search for asthma susceptibility loci in ethnically diverse populations. Nat Genet 1997: 15: 389-392.
    • (1997) Nat Genet , vol.15 , pp. 389-392
  • 16
    • 0032168750 scopus 로고    scopus 로고
    • New susceptibility locus for rheumatoid arthritis suggested by a genome-wide linkage study
    • Cornelies F, Faure S, Martinez M et al. New susceptibility locus for rheumatoid arthritis suggested by a genome-wide linkage study. Proc Natl Acad Sci USA 1998: 95: 10746-10750.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 10746-10750
    • Cornelies, F.1    Faure, S.2    Martinez, M.3
  • 17
    • 10544220423 scopus 로고    scopus 로고
    • A complete genome screen for genes predisposing to severe bipolar disorder in two Costa Rican pedigrees
    • McInnes L A, Escamilla M A, Service S K et al. A complete genome screen for genes predisposing to severe bipolar disorder in two Costa Rican pedigrees. Proc Natl Acad Sci USA 1996: 93: 13060-13065.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 13060-13065
    • McInnes, L.A.1    Escamilla, M.A.2    Service, S.K.3
  • 18
    • 16044373177 scopus 로고    scopus 로고
    • Two stage genome-wide search in inflammatory bowel disease provides evidence for susceptibility loci on chromosomes 3, 7 and 12
    • Satsangi J, Parkes M, Louis E et al. Two stage genome-wide search in inflammatory bowel disease provides evidence for susceptibility loci on chromosomes 3, 7 and 12. Nat Genet 1996: 14: 199-202.
    • (1996) Nat Genet , vol.14 , pp. 199-202
    • Satsangi, J.1    Parkes, M.2    Louis, E.3
  • 19
    • 0025008677 scopus 로고
    • Linkage strategies for genetically complex traits II. The power of affected relative pairs
    • Risch N. Linkage strategies for genetically complex traits II. The power of affected relative pairs. Am J Hum Genet 1990: 46: 229-241.
    • (1990) Am J Hum Genet , vol.46 , pp. 229-241
    • Risch, N.1
  • 20
    • 0026725963 scopus 로고
    • The genetic risk for alopecia areata in first degree relatives of severely affected patients. An estimate
    • Van der Steen P, Traupe H, Happle R, Boezeman J, Strater R, Hann H. The genetic risk for alopecia areata in first degree relatives of severely affected patients. An estimate. Acta Derm Venereol 1992: 72: 373-375.
    • (1992) Acta Derm Venereol , vol.72 , pp. 373-375
    • Van Der Steen, P.1    Traupe, H.2    Happle, R.3    Boezeman, J.4    Strater, R.5    Hann, H.6
  • 21
    • 0021523844 scopus 로고
    • The inheritance of common baldness. Two B or not Two B?
    • Kuster W, Happle R. The Inheritance of Common Baldness. Two B or not Two B? J Am Acad Dermatol 1984: 11: 921-926.
    • (1984) J Am Acad Dermatol , vol.11 , pp. 921-926
    • Kuster, W.1    Happle, R.2
  • 22
    • 0016029730 scopus 로고
    • Natural history of psoriasis in 61 twin pairs
    • Farber E M, Nall L, Watson W. Natural history of psoriasis in 61 twin pairs. Arch Dermatol 1974: 109: 207-211.
    • (1974) Arch Dermatol , vol.109 , pp. 207-211
    • Farber, E.M.1    Nall, L.2    Watson, W.3
  • 23
    • 85038130302 scopus 로고    scopus 로고
    • http://www.sph.uth.tmc.edu/RetNet/
  • 24
    • 0343158231 scopus 로고    scopus 로고
    • A review of gene mapping in the 20th and 21st centuries: Statistical methods, data analysis, and experimental design
    • in press
    • Terwilliger J D, Göring H H H. A review of gene mapping in the 20th and 21st centuries: statistical methods, data analysis, and experimental design. Hum Biology 2000: (in press).
    • (2000) Hum Biology
    • Terwilliger, J.D.1    Göring, H.H.H.2
  • 25
    • 17144456542 scopus 로고    scopus 로고
    • TULP1 mutation in two extended Dominican kindreds with autosomal recessive retinitis pigmentosa
    • Banerjee P, Kleyn P W, Knowles J A et al. TULP1 mutation in two extended Dominican kindreds with autosomal recessive retinitis pigmentosa. Nat Genet 1998: 18:177-179.
    • (1998) Nat Genet , vol.18 , pp. 177-179
    • Banerjee, P.1    Kleyn, P.W.2    Knowles, J.A.3
  • 27
    • 0000874908 scopus 로고    scopus 로고
    • Linkage analysis in the presence of errors IV: Joint pseudomarker analysis of linkage and/or LD on a mixture of pedigrees and singletons when the mode of inheritance cannot be accurately specified
    • in press
    • Göring HHH, Terwilliger J D. Linkage analysis in the presence of errors IV: Joint pseudomarker analysis of linkage and/or LD on a mixture of pedigrees and singletons when the mode of inheritance cannot be accurately specified. Am J Hum Genet 2000: (in press).
    • (2000) Am J Hum Genet
    • Göring, H.H.H.1    Terwilliger, J.D.2
  • 28
    • 0034164617 scopus 로고    scopus 로고
    • Linkage analysis in the presence of errors III: Marker loci and their map as nuisance parameters
    • in press
    • Göring HHH, Terwilliger J D. Linkage analysis in the presence of errors III: Marker loci and their map as nuisance parameters. Am J Hum Genet 2000: (in press).
    • (2000) Am J Hum Genet
    • Göring, H.H.H.1    Terwilliger, J.D.2
  • 29
    • 0043048571 scopus 로고
    • Sequential tests for the detection of linkage
    • Morton N E. Sequential tests for the detection of linkage. Am J Hum Genet 1955: 7: 277-318.
    • (1955) Am J Hum Genet , vol.7 , pp. 277-318
    • Morton, N.E.1
  • 30
    • 0028877463 scopus 로고
    • Genetic dissection of complex traits: Guidelines for interpreting and reporting linkage reports
    • Lander E, Kruglyak L. Genetic dissection of complex traits: guidelines for interpreting and reporting linkage reports. Nat Genet 1995: 11: 241-247.
    • (1995) Nat Genet , vol.11 , pp. 241-247
    • Lander, E.1    Kruglyak, L.2
  • 31
    • 0027529253 scopus 로고
    • Asymptotic properties of affected-sib-pair linkage analysis
    • Holmans P. Asymptotic properties of affected-sib-pair linkage analysis. Am J Hum Genet 1993: 52: 362-374.
    • (1993) Am J Hum Genet , vol.52 , pp. 362-374
    • Holmans, P.1
  • 32
    • 0031979443 scopus 로고    scopus 로고
    • Significance levels in complex inheritance
    • Morton N E. Significance levels in complex inheritance. Am J Hum Genet 1998: 62: 690-697.
    • (1998) Am J Hum Genet , vol.62 , pp. 690-697
    • Morton, N.E.1
  • 33
    • 0031066950 scopus 로고    scopus 로고
    • Algorithms and inferences: The challenge of multifactorial diseases
    • Elston R C. Algorithms and inferences: the challenge of multifactorial diseases. Am J Hum Genet 1997: 60: 255-262.
    • (1997) Am J Hum Genet , vol.60 , pp. 255-262
    • Elston, R.C.1
  • 34
    • 0027495139 scopus 로고
    • Joint linkage of multiple loci for a complex disorder
    • MacLean C J, Sham P C, Kendler K S. Joint linkage of multiple loci for a complex disorder. Am J Hum Genet 1993: 53: 353-366.
    • (1993) Am J Hum Genet , vol.53 , pp. 353-366
    • Maclean, C.J.1    Sham, P.C.2    Kendler, K.S.3
  • 35
    • 0001395571 scopus 로고
    • Testing for heterogeneity of recombination fraction values in human genetics
    • Smith C A B. Testing for heterogeneity of recombination fraction values in human genetics. Am J Hum Genet 1963: 27: 175-182.
    • (1963) Am J Hum Genet , vol.27 , pp. 175-182
    • Smith, C.A.B.1
  • 37
    • 0015504339 scopus 로고
    • Histocompatibility (HL-A) antigens associated with psoriasis
    • Russell T J, Schuhes L M, Kuban D J. Histocompatibility (HL-A) antigens associated with psoriasis. N Eng J Med 1972: 287: 738-743.
    • (1972) N Eng J Med , vol.287 , pp. 738-743
    • Russell, T.J.1    Schuhes, L.M.2    Kuban, D.J.3
  • 38
    • 8244228677 scopus 로고    scopus 로고
    • Identification of a major susceptibility locus on chromosome 6p and evidence for further disease loci revealed by a two stage genome-wide search in psoriasis
    • Trembath R C, Lee Clough R, Rosbotham J L et al. Identification of a major susceptibility locus on chromosome 6p and evidence for further disease loci revealed by a two stage genome-wide search in psoriasis. Hum Molec Genet 1997: 6: 813-820.
    • (1997) Hum Molec Genet , vol.6 , pp. 813-820
    • Trembath, R.C.1    Lee Clough, R.2    Rosbotham, J.L.3
  • 39
    • 0343410359 scopus 로고    scopus 로고
    • Evidence for two psoriasis susceptibility loci (HLA and 17q) and two novel candidate regions (16q and 20p) by genome-wide scan
    • Nair R P, Henseler T, Jenisch S et al. Evidence for two psoriasis susceptibility loci (HLA and 17q) and two novel candidate regions (16q and 20p) by genome-wide scan. Hum Molec Genet 1997: 6: 1349-1356.
    • (1997) Hum Molec Genet , vol.6 , pp. 1349-1356
    • Nair, R.P.1    Henseler, T.2    Jenisch, S.3
  • 40
    • 0032231730 scopus 로고    scopus 로고
    • Linkage analysis of human leukocyte antigen (HLA) markers in familial psoriasis: Strong disequilibrium effects provide evidence for a major determinant in the HLA-B/-C region
    • Jenisch S, Henseler T, Nair R P et al. Linkage analysis of human leukocyte antigen (HLA) markers in familial psoriasis: strong disequilibrium effects provide evidence for a major determinant in the HLA-B/-C region. Am J Hum Genet 1998: 63: 191-199.
    • (1998) Am J Hum Genet , vol.63 , pp. 191-199
    • Jenisch, S.1    Henseler, T.2    Nair, R.P.3
  • 41
    • 0031878501 scopus 로고    scopus 로고
    • Familial psoriasis and HLA-B: Unambiguous support for linkage in 97 published families
    • Leder R O, Mansbridge J N, Hallmayer J, Hodge S E. Familial psoriasis and HLA-B: unambiguous support for linkage in 97 published families. Hum Hered 1998: 48: 198-211.
    • (1998) Hum Hered , vol.48 , pp. 198-211
    • Leder, R.O.1    Mansbridge, J.N.2    Hallmayer, J.3    Hodge, S.E.4
  • 42
    • 85048353862 scopus 로고    scopus 로고
    • Psoriasis linkage in the HLA region
    • Leder R O, Hodge S E. Psoriasis linkage in the HLA region. Am J Hum Genet 1999: 64: 895.
    • (1999) Am J Hum Genet , vol.64 , pp. 895
    • Leder, R.O.1    Hodge, S.E.2
  • 43
    • 0028366154 scopus 로고
    • Gene for familial psoriasis susceptibility mapped to the distal end of human chromosome 17q
    • Tomfohrde J, Silverman A, Barnes R et al. Gene for familial psoriasis susceptibility mapped to the distal end of human chromosome 17q. Science 1994: 264: 1141-1145.
    • (1994) Science , vol.264 , pp. 1141-1145
    • Tomfohrde, J.1    Silverman, A.2    Barnes, R.3
  • 44
    • 0032900956 scopus 로고    scopus 로고
    • Searching for psoriasis susceptibility genes in Italy: Genome scan and evidence for a new locus on chromosome 1
    • Capon F, Novelli G, Semprini S et al. Searching for psoriasis susceptibility genes in Italy: Genome scan and evidence for a new locus on chromosome 1. J Invest Dermatol 1999: 112: 32-35.
    • (1999) J Invest Dermatol , vol.112 , pp. 32-35
    • Capon, F.1    Novelli, G.2    Semprini, S.3
  • 45
    • 0029819846 scopus 로고    scopus 로고
    • Evidence that a locus for familial psoriasis maps to chromosome 4q
    • Matthews D, Fry L, Powles A et al. Evidence that a locus for familial psoriasis maps to chromosome 4q. Nat Genet 1996: 14: 231-233.
    • (1996) Nat Genet , vol.14 , pp. 231-233
    • Matthews, D.1    Fry, L.2    Powles, A.3
  • 46
    • 0031708739 scopus 로고    scopus 로고
    • The genetics of psoriasis: A complex disorder of the skin and immune system
    • Bhalerao J, Bowcock A M. The genetics of psoriasis: a complex disorder of the skin and immune system. Hum Molec Genet 1998: 7: 1537-1545.
    • (1998) Hum Molec Genet , vol.7 , pp. 1537-1545
    • Bhalerao, J.1    Bowcock, A.M.2
  • 47
    • 0033361017 scopus 로고    scopus 로고
    • A comprehensive linkage analysis of chromosome 21q22 supports prior evidence for a putative bipolar affective disorder locus
    • Aita V M, Liu J, Knowles J A et al. A comprehensive linkage analysis of chromosome 21q22 supports prior evidence for a putative bipolar affective disorder locus. Am J Hum Genet 1999: 64: 210-217.
    • (1999) Am J Hum Genet , vol.64 , pp. 210-217
    • Aita, V.M.1    Liu, J.2    Knowles, J.A.3
  • 49
    • 0033010024 scopus 로고    scopus 로고
    • Analysis of three suggested psoriasis susceptibility loci in a large Swedish set of families: Confirmation of linkage to chromosome 6p (HLA region), and to 17q, but not to 4q
    • Enlund F, Samuelsson L, Enerback C et al. Analysis of three suggested psoriasis susceptibility loci in a large Swedish set of families: confirmation of linkage to chromosome 6p (HLA region), and to 17q, but not to 4q. Hum Hered 1999: 49: 2-8.
    • (1999) Hum Hered , vol.49 , pp. 2-8
    • Enlund, F.1    Samuelsson, L.2    Enerback, C.3
  • 50
    • 0345454376 scopus 로고    scopus 로고
    • The reninangiotensin-system in essential hypertension: Evidence for involvement of the angiotensin receptor type-I gene in Finnish patients
    • in press
    • Kainulainen K, Perola M, Terwilliger J D et al. The reninangiotensin-system in essential hypertension: Evidence for involvement of the angiotensin receptor type-I gene in Finnish patients. Hypertension 1999: (in press).
    • (1999) Hypertension
    • Kainulainen, K.1    Perola, M.2    Terwilliger, J.D.3
  • 51
    • 0033942602 scopus 로고    scopus 로고
    • Linkage analysis in the presence of errors I: Complex-valued recombination fractions and complex phenotypes
    • in press
    • Göring H H H, Terwilliger J D. Linkage analysis in the presence of errors I: Complex-valued recombination fractions and complex phenotypes. Am J Hum Genet 2000: (in press).
    • (2000) Am J Hum Genet
    • Göring, H.H.H.1    Terwilliger, J.D.2
  • 52
    • 0015309467 scopus 로고
    • The investigation of linkage between a quantitative trait and a marker locus
    • Haseman J K, Elston R C. The investigation of linkage between a quantitative trait and a marker locus. Behav Genet 1972: 2: 3-19.
    • (1972) Behav Genet , vol.2 , pp. 3-19
    • Haseman, J.K.1    Elston, R.C.2
  • 53
    • 0000877874 scopus 로고
    • The detection of autosomal linkage in data which consists of pairs of brothers and sisters
    • Penrose L S. The detection of autosomal linkage in data which consists of pairs of brothers and sisters. Ann Eugen 1935: 6: 133-138.
    • (1935) Ann Eugen , vol.6 , pp. 133-138
    • Penrose, L.S.1
  • 54
    • 0028123781 scopus 로고
    • Linkage analysis in nuclear families. Relationship between affected sibpair tests and lod score analysis
    • Knapp M, Seuchter S A, Baur M P. Linkage analysis in nuclear families. Relationship between affected sibpair tests and lod score analysis. Hum Hered 1994: 44: 44-51.
    • (1994) Hum Hered , vol.44 , pp. 44-51
    • Knapp, M.1    Seuchter, S.A.2    Baur, M.P.3
  • 55
    • 0025377248 scopus 로고
    • Cutting a Gordian knot in the linkage analysis of complex human traits
    • Ott J. Cutting a Gordian knot in the linkage analysis of complex human traits. Am J Hum Genet 1990: 46: 219-221.
    • (1990) Am J Hum Genet , vol.46 , pp. 219-221
    • Ott, J.1
  • 56
    • 13344259990 scopus 로고    scopus 로고
    • Mapping of a susceptibility locus for Crohn's disease on chromosome 16
    • Hugot J P, Laurent-Puig P, Gower-Tousseau C et al. Mapping of a susceptibility locus for Crohn's disease on chromosome 16. Nature 1996: 379: 821-823.
    • (1996) Nature , vol.379 , pp. 821-823
    • Hugot, J.P.1    Laurent-Puig, P.2    Gower-Tousseau, C.3
  • 57
    • 0025324698 scopus 로고
    • Increased occurrence of psoriasis in patients with Crohn's disease and their relatives
    • Lee F I, Bellary S V, Francis C. Increased occurrence of psoriasis in patients with Crohn's disease and their relatives. Am J Gastroenetrol 1990: 85: 962-963.
    • (1990) Am J Gastroenetrol , vol.85 , pp. 962-963
    • Lee, F.I.1    Bellary, S.V.2    Francis, C.3
  • 59
    • 0029886532 scopus 로고    scopus 로고
    • Parametric and nonparametric linkage analysis: A unified multipoint approach
    • Kruglyak L, Daly M J, Reeve-Daly M P, Lander E S. Parametric and nonparametric linkage analysis: a unified multipoint approach. Am J Hum Genet 1996: 58: 1347-1363.
    • (1996) Am J Hum Genet , vol.58 , pp. 1347-1363
    • Kruglyak, L.1    Daly, M.J.2    Reeve-Daly, M.P.3    Lander, E.S.4
  • 60
    • 0031765376 scopus 로고    scopus 로고
    • HLA DR2 and DQ1 frequency among narcoleptic patients in Hong Kong Chinese
    • Wing Y K, Chen C N, Ho C K. HLA DR2 and DQ1 frequency among narcoleptic patients in Hong Kong Chinese. Psychiatry Clin Neurosci 1998: 52: 523-527.
    • (1998) Psychiatry Clin Neurosci , vol.52 , pp. 523-527
    • Wing, Y.K.1    Chen, C.N.2    Ho, C.K.3
  • 62
    • 15144361587 scopus 로고    scopus 로고
    • Linkage disequilibrium between the human leukocyte antigen class II region of the major histocompatibility complex and Graves' disease: Replication using a population case control and family-based study
    • Heward J M, Allahabadia A, Daykin J et al. Linkage disequilibrium between the human leukocyte antigen class II region of the major histocompatibility complex and Graves' disease: replication using a population case control and family-based study. J Clin Endocrinol Metab 1998: 83: 3394-3397.
    • (1998) J Clin Endocrinol Metab , vol.83 , pp. 3394-3397
    • Heward, J.M.1    Allahabadia, A.2    Daykin, J.3
  • 63
    • 0033237816 scopus 로고    scopus 로고
    • The critical region for behcet disease in the human major histocompatibility complex is reduced to a 46-kb segment centromeric of HLA-B, by association analysis using refined microsatellite mapping
    • Ota M, Mizuki N, Katsuyama Y et al. The Critical Region for Behcet Disease in the Human Major Histocompatibility Complex Is Reduced to a 46-kb Segment Centromeric of HLA-B, by Association Analysis Using Refined Microsatellite Mapping. Am J Hum Genet 1999: 64: 1406-1410.
    • (1999) Am J Hum Genet , vol.64 , pp. 1406-1410
    • Ota, M.1    Mizuki, N.2    Katsuyama, Y.3
  • 65
    • 0033358374 scopus 로고    scopus 로고
    • The predisposition to type 1 diabetes linked to the human leukocyte antigen complex includes at least one non-class II gene
    • Lie B A, Todd J A, Pociot F et al. The predisposition to type 1 diabetes linked to the human leukocyte antigen complex includes at least one non-class II gene. Am J Hum Genet 1999: 64: 793-800.
    • (1999) Am J Hum Genet , vol.64 , pp. 793-800
    • Lie, B.A.1    Todd, J.A.2    Pociot, F.3
  • 66
    • 0032994414 scopus 로고    scopus 로고
    • Significant association of HLA-B and HLA-DRB1 alleles with cleft lip with or without cleft palate
    • Sakata Y, Tokunaga K, Yonehara Y et al. Significant association of HLA-B and HLA-DRB1 alleles with cleft lip with or without cleft palate. Tissue Antigens 1999: 53: 147-152.
    • (1999) Tissue Antigens , vol.53 , pp. 147-152
    • Sakata, Y.1    Tokunaga, K.2    Yonehara, Y.3
  • 67
    • 0032963059 scopus 로고    scopus 로고
    • HLA-DQ-associated predisposition to and dominant HLA-DR-associated protection against rheumatoid arthritis
    • van der Horst-Bruinsma I E, Visser H, Hazes J M et al. HLA-DQ-associated predisposition to and dominant HLA-DR-associated protection against rheumatoid arthritis. Hum Immunol 1999: 60: 152-158.
    • (1999) Hum Immunol , vol.60 , pp. 152-158
    • Van Der Horst-Bruinsma, I.E.1    Visser, H.2    Hazes, J.M.3
  • 69
    • 0027942323 scopus 로고
    • Genome screening by searching for shared segments: Mapping a gene for benign recurrent intrahepatic cholestasis
    • Houwen R H J, Baharloo S, Blankenship K et al. Genome screening by searching for shared segments: mapping a gene for benign recurrent intrahepatic cholestasis. Nat Genet 1994: 8: 380-386.
    • (1994) Nat Genet , vol.8 , pp. 380-386
    • Houwen, R.H.J.1    Baharloo, S.2    Blankenship, K.3
  • 70
    • 0028949919 scopus 로고
    • Random search for shared chromosomal regions in four affected individuals: The assignment of a new hereditary ataxia locus
    • Nikali K, Suomalainen A, Terwilliger J, Koskinen T, Weissenbach J, Peltonen L. Random search for shared chromosomal regions in four affected individuals: the assignment of a new hereditary ataxia locus. Am J Hum Genet 1995: 56: 1088-1095.
    • (1995) Am J Hum Genet , vol.56 , pp. 1088-1095
    • Nikali, K.1    Suomalainen, A.2    Terwilliger, J.3    Koskinen, T.4    Weissenbach, J.5    Peltonen, L.6
  • 71
    • 0032403973 scopus 로고    scopus 로고
    • Linkage disequilibrium mapping of complex disease: Fantasy or reality?
    • Terwilliger J D, Weiss K M. Linkage disequilibrium mapping of complex disease: fantasy or reality? Curr Op Biotechnol 1998: 9: 578-594.
    • (1998) Curr Op Biotechnol , vol.9 , pp. 578-594
    • Terwilliger, J.D.1    Weiss, K.M.2
  • 72
    • 0029422556 scopus 로고
    • Messages from an isolate: Lessons from the Finnish gene pool
    • Peltonen L, Pekkarinen P, Aaltonen J. Messages from an isolate: Lessons from the Finnish gene pool. Biol Chem Hoppe Seyler 1995: 376: 697-704.
    • (1995) Biol Chem Hoppe Seyler , vol.376 , pp. 697-704
    • Peltonen, L.1    Pekkarinen, P.2    Aaltonen, J.3
  • 73
    • 0031946381 scopus 로고    scopus 로고
    • Mapping genes through the use of Linkage Disequilibrium generated by genetic drift: "Drift mapping" in small populations with no demographic expansion
    • Terwilliger J D, Zollner S, Laan M, Paabo S. Mapping genes through the use of Linkage Disequilibrium generated by genetic drift: "Drift Mapping" in small populations with no demographic expansion. Hum Hered 1998: 48: 138-154.
    • (1998) Hum Hered , vol.48 , pp. 138-154
    • Terwilliger, J.D.1    Zollner, S.2    Laan, M.3    Paabo, S.4
  • 74
    • 0030667521 scopus 로고    scopus 로고
    • Demographic history and linkage disequilibrium in human populations
    • Laan M, Paabo S. Demographic history and linkage disequilibrium in human populations. Nat Genet 1997: 17: 435-438.
    • (1997) Nat Genet , vol.17 , pp. 435-438
    • Laan, M.1    Paabo, S.2
  • 75
    • 0029741063 scopus 로고    scopus 로고
    • The future of genetic studies of complex human diseases
    • Risch N, Merikangas K. The future of genetic studies of complex human diseases. Science 1996: 273: 1516-1517.
    • (1996) Science , vol.273 , pp. 1516-1517
    • Risch, N.1    Merikangas, K.2
  • 76
    • 0030078281 scopus 로고    scopus 로고
    • Is there a paradigm shift in genetics? Lessons from the study of human diseases
    • Weiss K. M. Is there a paradigm shift in genetics? Lessons from the study of human diseases. Mol Phylogenet Evol 1996: 5: 259-265.
    • (1996) Mol Phylogenet Evol , vol.5 , pp. 259-265
    • Weiss, K.M.1
  • 77
    • 0030869377 scopus 로고    scopus 로고
    • What is significant in whole-genome linkage disequilibrium studies?
    • Kruglyak L. What is significant in whole-genome linkage disequilibrium studies? Am J Hum Genet 1997: 61: 810-812.
    • (1997) Am J Hum Genet , vol.61 , pp. 810-812
    • Kruglyak, L.1
  • 78
    • 0027377799 scopus 로고
    • Transmission test for linkage disequilibrium: The insulin gene region and insulin-dependent diabetes mellitus (IDDM)
    • Spielman R S, McGinnis R E, Ewens W J. Transmission test for linkage disequilibrium: The insulin gene region and insulin-dependent diabetes mellitus (IDDM). Am J Hum Genet 1993: 52: 506-516.
    • (1993) Am J Hum Genet , vol.52 , pp. 506-516
    • Spielman, R.S.1    McGinnis, R.E.2    Ewens, W.J.3
  • 79
    • 0026494911 scopus 로고
    • A haplotype-based haplotype relative risk statistic
    • Terwilliger J D, Ott J. A haplotype-based haplotype relative risk statistic. Hum Hered 1992: 42: 337-346.
    • (1992) Hum Hered , vol.42 , pp. 337-346
    • Terwilliger, J.D.1    Ott, J.2
  • 80
    • 0024536523 scopus 로고
    • Statistical properties of the haplotype relative risk
    • Ott J. Statistical properties of the haplotype relative risk. Genet Epidemiol 1989: 6: 127-130.
    • (1989) Genet Epidemiol , vol.6 , pp. 127-130
    • Ott, J.1
  • 81
    • 0028030120 scopus 로고
    • Two-locus disease models with two marker loci: The power of affected-sib-pair tests
    • Knapp M, Seuchter S A, Baur M P Two-locus disease models with two marker loci: the power of affected-sib-pair tests. Am J Hum Genet 1994: 55: 1030-1041.
    • (1994) Am J Hum Genet , vol.55 , pp. 1030-1041
    • Knapp, M.1    Seuchter, S.A.2    Baur, M.P.3
  • 82
    • 0027430716 scopus 로고
    • Two-trait-locus linkage analysis: A powerful strategy for mapping complex genetic traits
    • Schork N J, Boehnke M, Terwilliger J D, Ott J. Two-trait-locus linkage analysis: a powerful strategy for mapping complex genetic traits. Am J Hum Genet 1993: 53: 1127-1136.
    • (1993) Am J Hum Genet , vol.53 , pp. 1127-1136
    • Schork, N.J.1    Boehnke, M.2    Terwilliger, J.D.3    Ott, J.4
  • 84
    • 0029061838 scopus 로고
    • Statistical methods for linkage analysis of complex traits from high-resolution maps of identity by descent
    • Dupuis J, Brown P O, Siegmund D. Statistical methods for linkage analysis of complex traits from high-resolution maps of identity by descent. Genetics 1995: 140: 843-856.
    • (1995) Genetics , vol.140 , pp. 843-856
    • Dupuis, J.1    Brown, P.O.2    Siegmund, D.3
  • 85
    • 85038131442 scopus 로고    scopus 로고
    • Likelihood-based multi-locus 2-point or multipoint, "model-based" or "model-free", linkage and/ or LD analysis as a generalization of the admixture test
    • under review
    • Terwilliger J D. Likelihood-based multi-locus 2-point or multipoint, "model-based" or "model-free", linkage and/ or LD analysis as a generalization of the admixture test. Eur J Hum Genet (under review).
    • Eur J Hum Genet
    • Terwilliger, J.D.1
  • 86
    • 0342263287 scopus 로고
    • On the interpretation of two-trait locus, two-marker locus lod scores
    • Terwilliger J D. On the interpretation of two-trait locus, two-marker locus lod scores. Psychiatr Genet 1993: 3: 136.
    • (1993) Psychiatr Genet , vol.3 , pp. 136
    • Terwilliger, J.D.1
  • 87
    • 0031469839 scopus 로고    scopus 로고
    • Neural network analysis of complex traits
    • Lucek P R, Ott J. Neural Network Analysis of Complex Traits. Genet Epidemiol 1997: 14: 1101-1106.
    • (1997) Genet Epidemiol , vol.14 , pp. 1101-1106
    • Lucek, P.R.1    Ott, J.2
  • 88
    • 0030861903 scopus 로고    scopus 로고
    • The use of a genetic map of biallelic markers in linkage studies
    • Kruglyak L. The use of a genetic map of biallelic markers in linkage studies. Nat Genet 1997: 17: 21-24.
    • (1997) Nat Genet , vol.17 , pp. 21-24
    • Kruglyak, L.1
  • 89
    • 0033042156 scopus 로고    scopus 로고
    • Efficient approach to unique single-nucleotide polymorphism discovery
    • Taillon-Miller P, Piernot E E, Kwok P-Y. Efficient approach to unique single-nucleotide polymorphism discovery. Genome Res 1999: 9: 499-505.
    • (1999) Genome Res , vol.9 , pp. 499-505
    • Taillon-Miller, P.1    Piernot, E.E.2    Kwok, P.-Y.3
  • 90
    • 0032940606 scopus 로고    scopus 로고
    • Microarrays and macroconsequences
    • Collins F S. Microarrays and macroconsequences. Nat Genet 1999: 21: 2.
    • (1999) Nat Genet , vol.21 , pp. 2
    • Collins, F.S.1
  • 91
    • 0026746111 scopus 로고
    • On the relative importance of marker heterozygosity and intermarker distance in gene mapping
    • Terwilliger J D, Ding Y, Ott J. On the relative importance of marker heterozygosity and intermarker distance in gene mapping. Genomics 1992: 13: 951-956.
    • (1992) Genomics , vol.13 , pp. 951-956
    • Terwilliger, J.D.1    Ding, Y.2    Ott, J.3
  • 92
    • 84984932946 scopus 로고    scopus 로고
    • Population genetics - Making sense out of sequence
    • Chakravarti A. Population genetics - making sense out of sequence. Nat Genet 1999: 21: 56-60.
    • (1999) Nat Genet , vol.21 , pp. 56-60
    • Chakravarti, A.1
  • 94
    • 0031834225 scopus 로고    scopus 로고
    • It's raining SNPs, hallelujah?
    • Chakravarti A. It's raining SNPs, hallelujah? Nat Genet 1998: 19: 216-217.
    • (1998) Nat Genet , vol.19 , pp. 216-217
    • Chakravarti, A.1
  • 96
    • 0014421064 scopus 로고
    • Evolutionary rate at the molecular level
    • Kimura M. Evolutionary rate at the molecular level. Nature 1968: 217: 624-626.
    • (1968) Nature , vol.217 , pp. 624-626
    • Kimura, M.1
  • 98
    • 0024356362 scopus 로고
    • The neutral theory of molecular evolution and the world view of the neutralists
    • Kimura M. The neutral theory of molecular evolution and the world view of the neutralists. Genome 1989: 31: 24-31.
    • (1989) Genome , vol.31 , pp. 24-31
    • Kimura, M.1
  • 99
    • 0016087667 scopus 로고
    • On some principles governing molecular evolution
    • Kimura M, Ohta T. On some principles governing molecular evolution. Proc Natl Acad Sci USA 1974: 71: 2848-2852.
    • (1974) Proc Natl Acad Sci USA , vol.71 , pp. 2848-2852
    • Kimura, M.1    Ohta, T.2
  • 100
    • 0002053867 scopus 로고
    • Natural selection
    • Bell P R, ed. Cambridge, UK: Cambridge University Press
    • Haldane J B S. Natural Selection In: Bell P R, ed. Darwin's biological work. Cambridge, UK: Cambridge University Press, 1959: pp. 101-149.
    • (1959) Darwin's Biological Work , pp. 101-149
    • Haldane, J.B.S.1
  • 101
    • 0342947190 scopus 로고
    • Possibility of extensive neutral evolution under stabilizing selection with special reference to non-random usage of synonymous codons
    • Kimura M. Possibility of extensive neutral evolution under stabilizing selection with special reference to non-random usage of synonymous codons. Proc Natl Acad Sci USA 1981: 78: 5773-5777.
    • (1981) Proc Natl Acad Sci USA , vol.78 , pp. 5773-5777
    • Kimura, M.1
  • 103
    • 0015862142 scopus 로고
    • The age of a neutral mutant persisting in a finite population
    • Kimura M, Ohta T. The age of a neutral mutant persisting in a finite population. Genetics 1973: 75: 199-212.
    • (1973) Genetics , vol.75 , pp. 199-212
    • Kimura, M.1    Ohta, T.2
  • 104
    • 0000660047 scopus 로고
    • Diffusion models in population genetics
    • Kimura M. Diffusion models in population genetics. J Appl Probab 1964: 1: 177-232.
    • (1964) J Appl Probab , vol.1 , pp. 177-232
    • Kimura, M.1
  • 105
    • 17344364213 scopus 로고    scopus 로고
    • DNA sequence diversity in 9.7 kb region of the human lipoprotein lipase gene
    • Nickerson D A, Taylor S L, Weiss K M et al. DNA sequence diversity in 9.7 kb region of the human lipoprotein lipase gene. Nat Genet 1998: 19: 233-240.
    • (1998) Nat Genet , vol.19 , pp. 233-240
    • Nickerson, D.A.1    Taylor, S.L.2    Weiss, K.M.3
  • 106
    • 0032231888 scopus 로고    scopus 로고
    • Haplotype structure and population genetic inferences from nucleotide-sequence variation in human lipoprotein lipase
    • Clark A G, Weiss K M, Nickerson D A et al. Haplotype structure and population genetic inferences from nucleotide-sequence variation in human lipoprotein lipase. Am J Hum Genet 1998: 63: 595-612.
    • (1998) Am J Hum Genet , vol.63 , pp. 595-612
    • Clark, A.G.1    Weiss, K.M.2    Nickerson, D.A.3
  • 107
    • 0027521076 scopus 로고
    • The rise and fall of positional cloning?
    • Ballabio A. The rise and fall of positional cloning? Nat Genet 1993: 3: 277-279.
    • (1993) Nat Genet , vol.3 , pp. 277-279
    • Ballabio, A.1
  • 108
    • 0026849567 scopus 로고
    • Positional cloning: Let's not call it reverse anymore
    • Collins F. Positional cloning: let's not call it reverse anymore. Nat Genet 1992: 1: 3-6.
    • (1992) Nat Genet , vol.1 , pp. 3-6
    • Collins, F.1
  • 109
    • 0344160563 scopus 로고    scopus 로고
    • Linkage disequilibrium mapping of psoriasis susceptibility locus (PSORS1) on chromosome 6
    • Nair R, Stuart P, Henseler T et al. Linkage disequilibrium mapping of psoriasis susceptibility locus (PSORS1) on chromosome 6. J Invest Dermatol 1999: 112: 640.
    • (1999) J Invest Dermatol , vol.112 , pp. 640
    • Nair, R.1    Stuart, P.2    Henseler, T.3
  • 110
    • 0031658645 scopus 로고    scopus 로고
    • A practical guide to orient yourself in the labyrinth of genome databases
    • Borsani G, Ballabio A, Banfi S. A practical guide to orient yourself in the labyrinth of genome databases. Hum Molec Genet 1998: 7: 1641-1648.
    • (1998) Hum Molec Genet , vol.7 , pp. 1641-1648
    • Borsani, G.1    Ballabio, A.2    Banfi, S.3
  • 111
    • 85038141847 scopus 로고    scopus 로고
    • Cataloguing genes on human chromosome 21: Analysis of genomic sequence and relevance to Down syndrome
    • Gardiner K, Tong S, Shannon R, Mural R. Cataloguing genes on human chromosome 21: analysis of genomic sequence and relevance to Down syndrome. Am J Hum Genet 1998: 63:A249.
    • (1998) Am J Hum Genet , vol.63
    • Gardiner, K.1    Tong, S.2    Shannon, R.3    Mural, R.4
  • 112
    • 0030688004 scopus 로고    scopus 로고
    • Variations on a theme: Cataloging human DNA sequence variation
    • Collins F S, Guyer M S, Chakravarti A. Variations on a theme: cataloging human DNA sequence variation. Science 1997: 278: 1580-1581.
    • (1997) Science , vol.278 , pp. 1580-1581
    • Collins, F.S.1    Guyer, M.S.2    Chakravarti, A.3
  • 113
    • 0031679495 scopus 로고    scopus 로고
    • Array-based multiplex analysis of candidate genes reveals two independent and additive genetic risk factors for myocardial infarction in the Finnish population
    • Pastinen T, Perola M, Niini Pet al. Array-based multiplex analysis of candidate genes reveals two independent and additive genetic risk factors for myocardial infarction in the Finnish population. Hum Molec Genet 1998: 7: 1453-1462.
    • (1998) Hum Molec Genet , vol.7 , pp. 1453-1462
    • Pastinen, T.1    Perola, M.2    Niini, P.3
  • 114
    • 84984934752 scopus 로고    scopus 로고
    • Resequencing and mutational analysis using oligonucleotide microarrays
    • Hacia J G. Resequencing and mutational analysis using oligonucleotide microarrays. Nat Genet 1999: 21: 42-47.
    • (1999) Nat Genet , vol.21 , pp. 42-47
    • Hacia, J.G.1
  • 116
    • 84984932472 scopus 로고    scopus 로고
    • Exploring the new world of the genome with DNA microarrays
    • Brown P O, Botstein D. Exploring the new world of the genome with DNA microarrays. Nat Genet 1999: 21: 33-37.
    • (1999) Nat Genet , vol.21 , pp. 33-37
    • Brown, P.O.1    Botstein, D.2
  • 117
    • 0030012657 scopus 로고    scopus 로고
    • Human/mouse homology relationships
    • DeBry R W, Seldin M F. Human/mouse homology relationships. Genomics 1996: 33: 337-351.
    • (1996) Genomics , vol.33 , pp. 337-351
    • DeBry, R.W.1    Seldin, M.F.2
  • 118
    • 6844265562 scopus 로고    scopus 로고
    • Alopecia universalis associated with a mutation in the human hairless gene
    • Ahmad W, Faiyaz ul Haque M, Brancolini V et al. Alopecia universalis associated with a mutation in the human hairless gene. Science 1998: 279: 720-724.
    • (1998) Science , vol.279 , pp. 720-724
    • Ahmad, W.1    Faiyaz Ul Haque, M.2    Brancolini, V.3
  • 119
    • 0033535507 scopus 로고    scopus 로고
    • Exposing the human nude phenotype
    • Frank J, Pignata C, Panteleyev A A et al. Exposing the human nude phenotype. Nature 1999: 398: 473-474.
    • (1999) Nature , vol.398 , pp. 473-474
    • Frank, J.1    Pignata, C.2    Panteleyev, A.A.3
  • 122
    • 0030785132 scopus 로고    scopus 로고
    • Development of and progression of psoriasiform dermatitis and systemic lesions in the flaky skin (fsn) mouse mutant
    • Sundberg J P, France M, Boggess D et al. Development of and progression of psoriasiform dermatitis and systemic lesions in the flaky skin (fsn) mouse mutant. Pathobiology 1997: 65: 271-286.
    • (1997) Pathobiology , vol.65 , pp. 271-286
    • Sundberg, J.P.1    France, M.2    Boggess, D.3
  • 123
    • 0003074622 scopus 로고
    • Atlas of the mouse genome
    • Lyon M, Kirby M. Atlas of the mouse genome. Mouse Genome 1994: 92: 19.
    • (1994) Mouse Genome , vol.92 , pp. 19
    • Lyon, M.1    Kirby, M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.