Mapping genes through the use of linkage disequilibrium generated by genetic drift: 'Drift mapping' in small populations with no demographic expansion

Human Heredity

Volumn 48, Issue 3, 1998, Pages 138-154

  Terwilliger, Joseph D ^a,b,d   Zöllner, Sebastian ^c   Laan, Maris ^c   Pääbo, Svante ^c  

^a Columbia University ^*  (United States)

^b NEW YORK STATE PSYCHIATRIC INSTITUTE   (United States)

^c UNIVERSITY OF MUNICH   (Germany)

^d Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

Complex disease; Demographic history; Finns; Genetic drift; Linkage disequilibrium; Population isolate; Population structure; Saami

Indexed keywords

DEMOGRAPHY; FOUNDER EFFECT; GENE LINKAGE DISEQUILIBRIUM; GENE MAPPING; GENE MUTATION; GENETIC DRIFT; GENETIC HETEROGENEITY; GENETIC RECOMBINATION; INBREEDING; MODEL; POPULATION GENETICS; POPULATION MODEL; POPULATION STRUCTURE; REVIEW;

CHROMOSOME MAPPING; GENE FREQUENCY; GENETICS, POPULATION; HUMANS; LINKAGE DISEQUILIBRIUM; RECOMBINATION, GENETIC;

EID: 0031946381     PISSN: 00015652     EISSN: None     Source Type: Journal    
DOI: 10.1159/000022794     Document Type: Review

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