Analysis of MHC class II DP, DQ and DR alleles in Crohn's disease

Gut

Volumn 43, Issue 2, 1998, Pages 210-215

  Cariappa, A ^a   Sands, B ^b   Forcione, D ^a   Finkelstein, D ^a   Podolsky, D K ^b   Pillai, S ^a,c  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b Gastrointestinal Unit

^c MASSACHUSETTS GENERAL HOSPITAL CANCER CENTER   (United States)

Author keywords

Crohn's disease; Genetic susceptibility; HLA class II genes; Inflammatory bowel disease; Major histocompatibility complex

Indexed keywords

HLA DP ANTIGEN; HLA DQ ANTIGEN; HLA DR ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2;

ARTICLE; CONTROLLED STUDY; CROHN DISEASE; GENE FREQUENCY; GENETIC SUSCEPTIBILITY; HLA TYPING; HUMAN; HUMAN TISSUE; IMMUNOPHENOTYPING; MAJOR CLINICAL STUDY; MAJOR HISTOCOMPATIBILITY COMPLEX; PRIORITY JOURNAL;

EID: 0031850121     PISSN: 00175749     EISSN: None     Source Type: Journal    
DOI: 10.1136/gut.43.2.210     Document Type: Article

References (27)

1. Hugot J-P, Laurent-Puig P, Gower-Rousseau C, et al. Mapping of a susceptibility locus for Crohn's disease on chromosome 16. Nature 1996;379:821-3.
2. Ohmen JD, Yang HY, Yamamoto KK, et al. Susceptibility locus for inflammatory bowel disease on chromosome 16 has a role in Crohn's disease but not in ulcerative colitis. Hum Mol Genet 1996;5:1679-83.
3. Satsangi J, Welsh KI, Bunce M, et al. Contribution of genes of the major histocompatibility complex to susceptibility and disease phenotype in inflammatory bowel disease. Lancet 1996;347:1212-17.
4. Nakajima A, Matsuhashi N, Kodama T, et al. HLA linked susceptibility and resistance genes in Crohn's disease. Gastroenterology 1995;109:1462-7.
5. Zetterquist H, Broome U, Einarsson K, et al. HLA class II genes in primary sclerosing cholangitis and chronic inflammatory bowel disease: no HLA-DRw52a association in Swedish patients with sclerosing cholangitis. Gut 1992;33: 942-6.
6. Wassmuth R, Eastman S, Kockum I, et al. HLA DR and DQ RFLP analysis in Crohn's disease. Eur J Immunogenet 1993;20:429-33.
7. Toyoda H, Wang S, Yang H, et al. Distinct associations of HLA class II genes with inflammatory bowel disease. Gastroenterology 1993;109:1462-7.
8. Danze P-M, Colombel J-F, Jacquot S, et al. Association of HLA class II genes with susceptibility to Crohn's disease. Gut 1996;39:69-72.
9. Reinshagen M, Loeliger C, Kuehnl P, et al. HLA class II frequencies in Crohn's disease: a population based analysis in Germany. Gut 1996;38:538-42.
10. Forcione DG, Sands B, Isselbacher KJ, et al. An increased risk of Crohn's disease in individuals who inherit the HLA class II DRB3*0301 allele. Proc Natl Acad Sci USA 1996;93:5094-8.
11. Gorski J, Tilanus M, Giphart M, et al. Oligonucleotide genotyping shows that alleles at the HLA DRB3 locus of the DRw52 supertypic group segregate independently of known DR or Dw specificities. Immunogenetics 1987;25:79-83.
12. Heresbach D, Alizadeh M, Bretagne JF, et al. Investigation of the association of major histocompatibility complex genes including HLA class I, class II and TAP genes with clinical forms of Crohn's disease. Eur J Immunogenet 1996; 23:141-51.
13. Kimura A, Sasazuki T. Eleventh International Histocompatibility Workshop: protocol for the HLA DNA typing technique. In: Tsuji K, Aizawa M, Sasazuki T, eds. HLA 1991. Proceedings of the Eleventh International Histocompatibility Workshop and Conference. Volume 1. New York and Oxford: 1992:397-418.
14. Woolf B. On estimating the relationship between blood group and disease. Ann Hum Genet 1955;19:251-3.
15. Svejgaard A, Ryder LP. HLA and disease associations: detecting the strongest association. Tissue Antigens 1994;43: 18-27.
16. Imanishi T, Akaza T, Kimura A, et al. Allele and haplotype frequencies for HLA and complement loci in various ethnic groups. In: Tsuji K, Aizawa M, Sasazuki T, eds. HLA 1991. Proceedings of the Eleventh International Histocompatibility Workshop and Conference. Volume 1. New York and Oxford: 1992:1065-220.
17. Duerr RH, Neigut DA. Molecularly denned HLA-DR2 alleles in ulcerative colitis and an anti-neutrophil cytoplasmic antibody positive subgroup. Gastroenterology 1995;109: 1462-7.
18. Gulwani-Akolkar B, Akolkar PN, McKinley M, et al. Crohn's disease is accompanied by changes in the CD4+, but not CD8+ T cell receptor Vb repertoire of lamina propria lymphocytes. Clin Immunol Immunopathol 1905;77:95-106.
19. Probert CS, Chott A, Turner JR, et al. Persistent expansions of peripheral blood CD4+ lymphocytes in chronic inflammatory bowel disease. J Immunol 1996;157:3183-91.
20. Miller WL, Morel Y. The molecular genetics of 21-hydroxylase deficiency. Annu Rev Genet 1989;23:371-93.
21. Spielman RS, Nathenson N. The genetics of susceptibility to multiple sclerosis. Epidemiol Rev 1982;4:45-65.
22. Olerup O, Hillert J, Fredrickson S, et al. Primary chronic progressive and relapsing remitting multiple sclerosis: two immunogenetically distinct disease entities. Proc Natl Acad Sci USA 1989;86:7113-17.
23. Todd JA, Farrall M. Panning for gold: genome-wide scanning for linkage in type I diabetes. Hum Mol Genet 1996;5:1443-8.
24. Nepom GT, Erlich H. MHC class II molecules and autoimmunity. Annu Rev Immunol 1992;9:493-525.
25. Ota K, Matsui M, Milford EL, et al. T cell recognition of an immunodominant myelin basic protein epitope in multiple sclerosis. Nature 1990;346:183-7.
26. Roep BO. T cell responses to autoantigens in IDDM: the search for the Holy Grail. Diabetes 1996;45:1147-56.
27. Wucherpfennig KW, Strominger JC. Molecular mimicry in T cell mediated autoimmunity: viral peptides activate human T cell clones specific for myelin basic protein. Cell 199580:695-705.