Serotonin 5-HT2 receptor imaging in major depression: Focal changes in orbito-insular cortex

British Journal of Psychiatry

Volumn 171, Issue NOV., 1997, Pages 444-448

  Biver, F ^a   Wikler, D ^a   Lotstra, F ^a   Damhaut, P ^a   Goldman, S ^a   Mendlewicz, J ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

ALTANSERIN; FLUORINE 18; SEROTONIN 2 RECEPTOR; DIAGNOSTIC AGENT; DRUG DERIVATIVE; KETANSERIN; SEROTONIN ANTAGONIST; SEROTONIN RECEPTOR;

ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DEPRESSION; FEMALE; HAMILTON SCALE; HUMAN; INSULA; MALE; ORBITAL CORTEX; POSITRON EMISSION TOMOGRAPHY; BRAIN DISEASE; COMPUTER ASSISTED EMISSION TOMOGRAPHY; METABOLISM; METHODOLOGY; MIDDLE AGED; SCINTISCANNING;

BRAIN DISEASES; DEPRESSIVE DISORDER; FEMALE; HUMANS; KETANSERIN; MALE; MIDDLE AGED; RECEPTORS, SEROTONIN; SEROTONIN ANTAGONISTS; TOMOGRAPHY, EMISSION-COMPUTED;

EID: 0030608812     PISSN: 00071250     EISSN: None     Source Type: Journal    
DOI: 10.1192/bjp.171.5.444     Document Type: Article

References (32)

1. American Psychiatric Association (1987) Diagnostic and Statistical Manual of Mental Disorders (3rd edn, revised) (DSM-III-R). Washington, DC: APA.
2. Beckmann, H. & Jakob, H. (1991) Prenatal disturbances of nerve cell migration in the entorhinal region: a common vulnerability factor in functional psychosis? Journal of Neural Transmission, 84, 155-164.
3. Biver, F., Goldman, S., Delvenne, V., et al (1994a) Frontal and pariental metabolic disturbances in unipolar depression. Biological Psychiatry, 36, 381-388.
4. 2 receptors in human using positron emission tomography. European Journal of Nuclear Medicine, 21, 937-946.
5. 2 receptor in the living human brain. Neuroscience Letters, 204, 25-28.
6. 2 receptors: a film and electronic autoradiographic study. Nuclear Medicine and Biology, in press.
7. D'haenen, H., Bossuyt, A., Mertens, J., et al (1996) SPECT imaging of serotonin2 receptors in depression. Psychiatry Research, 45, 227-237.
8. Drevets, W. C., Videen, T. O., Price, J. L., et al (1992) A functional anatomical study of unipolar depression. Journal of Neuroscience, 12, 3628-3641.
9. Endicott, J. & Spitzer, R. L. (1978) A diagnostic interview: the schedule for affective disorders and schizophrenia. Archives of General Psychiatry, 35, 837-844.
10. Flor-Henry, P. (1985) Observations, reflection and speculation on the cerebral determinants of mood and on the bilaterally asymmetrical distribution of the major neurotransmitter systems. In Pharmacotherapy of Affective Disorders: Theory and Practice (eds W. G. Dewhurst & G. B. Baker), p. 151. London/Sidney: Croom Helm.
11. 2 receptor agonist, on local cerebral glucose metabolism in awake rats. Brain Research, 541, 63-69.
12. Friston, K. J., Holmes, A. P., Worsley, K. J., et al (1995) Statistical parametric maps in functional imaging: a general linear approach. Human Brain Mapping, 2, 189-210.
13. Goodwin, G. M. (1996) Functional imaging, affective disorder and dementia. British Medical Bulletin, 52, 495-512.
14. Gross-Isseroff, R., Israeli, M. & Biegon, A. (1989) Autoradiographic analysis of tritiated imipramine binding in the human brain post mortem: effect of suicide. Archives of General Psychiatry, 46, 237-241.
15. 3H]ketanserin binding in the human brain postmortem: effect of suicide. Brain Research, 507, 208-215.
16. Hamilton, M. (1990) A rating scale for depression. Journal of Neurology Neurosurgery and Psychiatry, 23, 56-62.
17. Lemaire, C., Cantineau, R., Guillaume, M., et al (1991) Fluorine-18-altanserin: a radioligand for the study of serotonin receptors with PET: radiolabeling and in vivo biologic behavior in rats. Journal of Nuclear Medicine, 32, 2266-2272.
18. 2 receptors in suicide victims: violence of death, depression and effects of antidepressant treatment. Brain Research, 642, 281-289.
19. Mayberg, H. S., Robinson, R. G., Wang, D. F., et al (1988) PET imaging of cortical S2 serotonin receptors after stroke: lateralized changes and relationship to depression. American Journal of Psychiatry, 145, 937-943.
20. McIntyre, M., Pritchard, P. B. & Lombrosco, C. T. (1976) Left and right temporal lobe epileptics: a controlled investigation of some psychological differences. Epilepsia, 17, 377-386.
21. Mesulam, M.-M. & Mufson, E. J. (1982) Insula of the old world monkey. III: Efferent cortical output and comments on function. Journal of Comparative Neurology, 212, 38-52.
22. Morecraft, R. J., Geula, C. & Mesulam, M.-M. (1992) Cytoarchitecture and neural afferents of orbitofrontal cortex in the brain of the monkey. Journal of Comparative Neurology, 323, 341-358.
23. Oldfield, R. C. (1971) The assessment and analysis of handedness: the Edinburgh Inventory. Neuropsychologia, 9, 97-113.
24. Overall, J. E. (1988) The brief psychiatric rating scale (BPRS): recent developments in ascertainment and scaling. Psychopharmacology Bulletin, 24, 97-99.
25. Pandev, G. N., Pandey, S. C., Dwivedi, Y., et al (1995) Platelet serotonin-2A receptors: a potential biological marker for suicidal behavior. American Journal of Psychiatry, 152, 850-855.
26. Peroutka, S. J. & Snyder, S. H. (1980) Long-term antidepressant treatment decreases spiroperidol-labeled serotonin receptor binding. Science, 210, 88-90.
27. Rauch, S. L., Savage, C. R., Alpert, N. M., et al (1995) A positron emission tomography study of simple phobic symptom provocation. Archives of General Psychiatry, 52, 20-28.
28. 18F]altanserin: results in young normal controls. Journal of Cerebral Blood Flow and Metabolism, 15, 787-797.
29. Stanley, M. & Mann, J. J. (1983) Increased serotonin-2 binding sites in frontal cortex of suicide victims. Lancet, i, 214-216.
30. Valenstein, E. & Heilman, K. M. (1979) Emotional disorders resulting from lesions of the central nervous system. In Clinical Neuropsychology (eds K. M. Heilman & E. Valenstein), pp. 413-438. New York: Oxford University Press.
31. Worsley, K. J., Evans, A. C., Marrett, S., et al (1992) A three-dimensional statistical analysis for rCBF activation studies in human brain. Journal of Cerebral Blood Flow and Metabolism, 12, 900-918.
32. 2 receptor changes in major depression. Biological Psychiatry, 27, 489-496.