메뉴 건너뛰기




Volumn 44, Issue 7, 1998, Pages 555-561

Assessment of serotonergic function in major depression using d- fenfluramine: Relation to clinical variables and antidepressant response

Author keywords

Antidepressants; Cortisol; d fenfluramine; Major depression; Prolactin; Serotonin

Indexed keywords

DESIPRAMINE; DEXFENFLURAMINE; HYDROCORTISONE; IMIPRAMINE; ORG 4428; PROLACTIN; SEROTONIN; UNCLASSIFIED DRUG;

EID: 0032191007     PISSN: 00063223     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-3223(98)00018-3     Document Type: Article
Times cited : (41)

References (46)
  • 2
    • 0023232461 scopus 로고
    • The dexamethasone suppression test: An overview of its current status in psychiatry
    • APA Task Force on Laboratory Tests in Psychiatry (1987): The dexamethasone suppression test: An overview of its current status in psychiatry. Am J Psychiatry 144:1253-1262.
    • (1987) Am J Psychiatry , vol.144 , pp. 1253-1262
  • 4
    • 0019256871 scopus 로고
    • The use of rating scales exemplified by a comparison of the Hamilton and Bech-Rafaelsen melancholia scale
    • Bech P, Rafaelsen OJ (1980): The use of rating scales exemplified by a comparison of the Hamilton and Bech-Rafaelsen melancholia scale. Acta Psychiatria Scand 62(suppl 285): 128-131.
    • (1980) Acta Psychiatria Scand , vol.62 , Issue.SUPPL. 285 , pp. 128-131
    • Bech, P.1    Rafaelsen, O.J.2
  • 5
    • 0019278247 scopus 로고
    • Neuroendocrine tests of monoamine function in man: A review of basic theory and its application to the study of depressive illness
    • Checkley SA (1980): Neuroendocrine tests of monoamine function in man: A review of basic theory and its application to the study of depressive illness. Psychol Med 10:35-53.
    • (1980) Psychol Med , vol.10 , pp. 35-53
    • Checkley, S.A.1
  • 6
    • 0029878811 scopus 로고    scopus 로고
    • Reduced prolactin and cortisol responses to d-fenfluramine in depressed compared to healthy matched control subjects
    • Cleare AJ, Murray RM, O'Keane V (1996): Reduced prolactin and cortisol responses to d-fenfluramine in depressed compared to healthy matched control subjects. Neuropsychopharmacology 14:349-354.
    • (1996) Neuropsychopharmacology , vol.14 , pp. 349-354
    • Cleare, A.J.1    Murray, R.M.2    O'Keane, V.3
  • 7
    • 0028178126 scopus 로고
    • 5-HT1A receptor sensitivity in major depression. A neuroendocrine study with buspirone
    • Cowen PJ, Power AC, Ware CJ, Anderson IM (1994): 5-HT1A receptor sensitivity in major depression. A neuroendocrine study with buspirone. Br J Psychiatry 164:372-379.
    • (1994) Br J Psychiatry , vol.164 , pp. 372-379
    • Cowen, P.J.1    Power, A.C.2    Ware, C.J.3    Anderson, I.M.4
  • 8
    • 0025318311 scopus 로고
    • Serotonin function and the mechanism of antidepressant action. Reversal of antidepressant-induced remission by rapid depletion of plasma tryptophan
    • Delgado PL, Charney DS, Price LH, Aghajanian GK, Landis H, Heninger GR (1990): Serotonin function and the mechanism of antidepressant action. Reversal of antidepressant-induced remission by rapid depletion of plasma tryptophan. Arch Gen Psychiatry 47:411-418.
    • (1990) Arch Gen Psychiatry , vol.47 , pp. 411-418
    • Delgado, P.L.1    Charney, D.S.2    Price, L.H.3    Aghajanian, G.K.4    Landis, H.5    Heninger, G.R.6
  • 9
    • 0028032353 scopus 로고
    • Serotonin and the neurobiology of depression. Effects of tryptophan depletion in drug-free depressed patients
    • Delgado PL, Price LH, Miller HL, et al (1994): Serotonin and the neurobiology of depression. Effects of tryptophan depletion in drug-free depressed patients. Arch Gen Psychiatry 51:865-874.
    • (1994) Arch Gen Psychiatry , vol.51 , pp. 865-874
    • Delgado, P.L.1    Price, L.H.2    Miller, H.L.3
  • 10
    • 0020959111 scopus 로고
    • The brief symptom inventory: An introductory report
    • Derogatis LR, Melisaratos N (1983): The Brief Symptom Inventory: An introductory report. Psychol Med 13:595-605.
    • (1983) Psychol Med , vol.13 , pp. 595-605
    • Derogatis, L.R.1    Melisaratos, N.2
  • 11
    • 0028299375 scopus 로고
    • Glucocorticoids and the genesis of depressive illness. A psychobiological model
    • Dinan TG (1994): Glucocorticoids and the genesis of depressive illness. A psychobiological model. Br J Psychiatry 164:365-371.
    • (1994) Br J Psychiatry , vol.164 , pp. 365-371
    • Dinan, T.G.1
  • 12
    • 0029917473 scopus 로고    scopus 로고
    • Serotonin and the regulation of hypothalamic-pituitary-adrenal function
    • Dinan TG (1996): Serotonin and the regulation of hypothalamic-pituitary-adrenal function. Life Sci 58:1683-1694.
    • (1996) Life Sci , vol.58 , pp. 1683-1694
    • Dinan, T.G.1
  • 13
    • 0027394851 scopus 로고
    • The prolactin response to d-and 1-fenfluramine and to d-amphetamine in human subjects
    • Feeney S, Goodall E, Silverstone T (1993): The prolactin response to d-and 1-fenfluramine and to d-amphetamine in human subjects. Int Clin Psychopharmacol 8:49-54.
    • (1993) Int Clin Psychopharmacol , vol.8 , pp. 49-54
    • Feeney, S.1    Goodall, E.2    Silverstone, T.3
  • 14
    • 0027360166 scopus 로고
    • Ritanserin attenuates anorectic, endocrine and thermic responses to d-fenfluramine in human volunteers
    • Goodall EM, Cowen PJ, Franklin M, Silverstone T (1993): Ritanserin attenuates anorectic, endocrine and thermic responses to d-fenfluramine in human volunteers. Psychopharmacology 112:461-466.
    • (1993) Psychopharmacology , vol.112 , pp. 461-466
    • Goodall, E.M.1    Cowen, P.J.2    Franklin, M.3    Silverstone, T.4
  • 15
    • 0027215459 scopus 로고
    • Plasma prolactin, adrenocorticotrophic hormone and cortisol after administration of d-fenfluramine or placebo to healthy subjects
    • Gorard DA, Taylor TM, Medbak SH, Perry LA, Libby GW, Farthing MJ (1993): Plasma prolactin, adrenocorticotrophic hormone and cortisol after administration of d-fenfluramine or placebo to healthy subjects. Int Clin Psychopharmacol 8:123-128.
    • (1993) Int Clin Psychopharmacol , vol.8 , pp. 123-128
    • Gorard, D.A.1    Taylor, T.M.2    Medbak, S.H.3    Perry, L.A.4    Libby, G.W.5    Farthing, M.J.6
  • 16
    • 51549099524 scopus 로고
    • The assessment of anxiety status by rating
    • Hamilton M (1959): The assessment of anxiety status by rating. Br J Med Psychol 32:50-55.
    • (1959) Br J Med Psychol , vol.32 , pp. 50-55
    • Hamilton, M.1
  • 18
    • 0022636781 scopus 로고
    • D-and L-isomers of fenfluramine differ markedly in their interaction with brain serotonin and cathecholamines in the rat
    • Invernizzi R, Berettera C, Garratini S, Samanin R (1986): D-and L-isomers of fenfluramine differ markedly in their interaction with brain serotonin and cathecholamines in the rat. Eur J Pharmacol 120:9-15.
    • (1986) Eur J Pharmacol , vol.120 , pp. 9-15
    • Invernizzi, R.1    Berettera, C.2    Garratini, S.3    Samanin, R.4
  • 19
    • 0025270126 scopus 로고
    • Multiple hormone responses to stimulation with dl-fenfluramine in patients with major depression before and after antidepressive treatment
    • Kasper S, Vieira A, Schmidt R, Richter P (1990): Multiple hormone responses to stimulation with dl-fenfluramine in patients with major depression before and after antidepressive treatment. Pharmacopsychiatry 23:76-84.
    • (1990) Pharmacopsychiatry , vol.23 , pp. 76-84
    • Kasper, S.1    Vieira, A.2    Schmidt, R.3    Richter, P.4
  • 21
    • 0021339840 scopus 로고
    • Serotonergic stimulation of adrenocorticotrophin secretion in man
    • Lewis DA, Sheerman BM (1984): Serotonergic stimulation of adrenocorticotrophin secretion in man. J Clin Endocrinol Metab 58:458-462.
    • (1984) J Clin Endocrinol Metab , vol.58 , pp. 458-462
    • Lewis, D.A.1    Sheerman, B.M.2
  • 22
    • 0022361313 scopus 로고
    • Serotonergic regulation of prolactin and growth hormone secretion in man
    • Lewis DA, Sherman BM (1985): Serotonergic regulation of prolactin and growth hormone secretion in man. Acta Endocrinol 110:152-157.
    • (1985) Acta Endocrinol , vol.110 , pp. 152-157
    • Lewis, D.A.1    Sherman, B.M.2
  • 23
    • 0023871540 scopus 로고
    • The fenfluramine challenge test in the affective spectrum: A possible marker of endogeneity and severity
    • Lopez Ibor JJ Jr, Saiz Ruiz J, Iglesias LM (1988): The fenfluramine challenge test in the affective spectrum: A possible marker of endogeneity and severity. Pharmacopsychiatry 21:9-14.
    • (1988) Pharmacopsychiatry , vol.21 , pp. 9-14
    • Lopez Ibor J.J., Jr.1    Saiz Ruiz, J.2    Iglesias, L.M.3
  • 24
    • 0000587671 scopus 로고
    • The serotonin hypothesis of major depression
    • Bloom FE, Kupfer DJ, editors. New York: Raven Press
    • Maes M, Meltzer HY (1995): The serotonin hypothesis of major depression. In: Bloom FE, Kupfer DJ, editors. Psychopharmacology: Fourth Generation of Progress. New York: Raven Press, pp 933-944.
    • (1995) Psychopharmacology: Fourth Generation of Progress , pp. 933-944
    • Maes, M.1    Meltzer, H.Y.2
  • 26
    • 0027433887 scopus 로고
    • Fenfluramine challenge test as a predictor of outcome in major depression
    • Malone KM, Thase ME, Mieczkowski T, et al (1993): Fenfluramine challenge test as a predictor of outcome in major depression. Psychopharmacol Bull 29:155-161.
    • (1993) Psychopharmacol Bull , vol.29 , pp. 155-161
    • Malone, K.M.1    Thase, M.E.2    Mieczkowski, T.3
  • 28
    • 0029125131 scopus 로고
    • Prolactin response to buspirone challenge in the presence of dopaminergic blockade
    • Maskall DD, Zis AP, Lam RW, Clark CM, Kuan AJ (1995): Prolactin response to buspirone challenge in the presence of dopaminergic blockade. Biol Psychiatry 38:235-239.
    • (1995) Biol Psychiatry , vol.38 , pp. 235-239
    • Maskall, D.D.1    Zis, A.P.2    Lam, R.W.3    Clark, C.M.4    Kuan, A.J.5
  • 29
    • 0029075949 scopus 로고
    • Effect of pindolol pretreatment on MK-212-induced plasma cortisol and prolactin responses in normal men
    • Meltzer HY, Maes M (1995a): Effect of pindolol pretreatment on MK-212-induced plasma cortisol and prolactin responses in normal men. Biol Psychiatry 38:310-318.
    • (1995) Biol Psychiatry , vol.38 , pp. 310-318
    • Meltzer, H.Y.1    Maes, M.2
  • 30
    • 0028856757 scopus 로고
    • Pindolol pretreatment blocks stimulation by meta-chlorophenylpiperazine of prolactin but not cortisol secretion in normal men
    • Meltzer HY, Maes M (1995b): Pindolol pretreatment blocks stimulation by meta-chlorophenylpiperazine of prolactin but not cortisol secretion in normal men. Psychiatry Res 58:89-98.
    • (1995) Psychiatry Res , vol.58 , pp. 89-98
    • Meltzer, H.Y.1    Maes, M.2
  • 31
    • 0021322437 scopus 로고
    • Effect of 5-hydroxytryptophan on serum cortisol levels in major affective disorders. I. Enhanced response in depression and mania
    • Meltzer HY, Umberkoman Wiita B, Robertson A, Tricou BJ, Lowy M, Perline R (1984): Effect of 5-hydroxytryptophan on serum cortisol levels in major affective disorders. I. Enhanced response in depression and mania. Arch Gen Psychiatry 41:366-374.
    • (1984) Arch Gen Psychiatry , vol.41 , pp. 366-374
    • Meltzer, H.Y.1    Umberkoman Wiita, B.2    Robertson, A.3    Tricou, B.J.4    Lowy, M.5    Perline, R.6
  • 32
    • 0025266060 scopus 로고
    • Hormonal responses to fenfluramine in depressed and control subjects
    • Mitchell P, Smythe G (1990): Hormonal responses to fenfluramine in depressed and control subjects. J Affect Disord 19:43-51.
    • (1990) J Affect Disord , vol.19 , pp. 43-51
    • Mitchell, P.1    Smythe, G.2
  • 33
    • 0025121941 scopus 로고
    • Plasma ratio tryptophan/neutral amino acids in relation to clinical response to paroxetine and clomipramine in patients with major depression
    • Moller SE, Bech P, Bjerrum H, et al (1990): Plasma ratio tryptophan/neutral amino acids in relation to clinical response to paroxetine and clomipramine in patients with major depression. J Affect Disord 18:59-66.
    • (1990) J Affect Disord , vol.18 , pp. 59-66
    • Moller, S.E.1    Bech, P.2    Bjerrum, H.3
  • 34
    • 0018425438 scopus 로고
    • A new depression scale designed to be sensitive to change
    • Montgomery S, Asberg M (1979): A new depression scale designed to be sensitive to change. Br J Psychiatry 134:382-389.
    • (1979) Br J Psychiatry , vol.134 , pp. 382-389
    • Montgomery, S.1    Asberg, M.2
  • 35
    • 0025850790 scopus 로고
    • Prolactin and cortisol responses to d-fenfluramine in major depression: Evidence for diminished responsivity of central serotonergic function
    • O'Keane V, Dinan TG (1991): Prolactin and cortisol responses to d-fenfluramine in major depression: Evidence for diminished responsivity of central serotonergic function. Am J Psychiatry 148:1009-1015.
    • (1991) Am J Psychiatry , vol.148 , pp. 1009-1015
    • O'Keane, V.1    Dinan, T.G.2
  • 36
    • 0025969636 scopus 로고
    • d-fenfluramine/prolactin response throughout the menstrual cycle: Evidence for an oestrogen-induced alteration
    • O'Keane V, O'Hanlon M, Webb M, Dinan T (1991): d-fenfluramine/prolactin response throughout the menstrual cycle: Evidence for an oestrogen-induced alteration. Clin Endocrinol 34:289-292.
    • (1991) Clin Endocrinol , vol.34 , pp. 289-292
    • O'Keane, V.1    O'Hanlon, M.2    Webb, M.3    Dinan, T.4
  • 38
    • 0028947233 scopus 로고
    • Effect of pindolol on the prolactin response to d-fenfluramine
    • Park SB, Cowen PJ (1995): Effect of pindolol on the prolactin response to d-fenfluramine. Psychopharmacology 118:471-474.
    • (1995) Psychopharmacology , vol.118 , pp. 471-474
    • Park, S.B.1    Cowen, P.J.2
  • 39
    • 0028886567 scopus 로고
    • Do the endocrine and subjective effects of d-fenfluramine predict response to selective serotonin reuptake inhibitors?
    • Park SBG, Williamson DJ, Cowen PJ (1995): Do the endocrine and subjective effects of d-fenfluramine predict response to selective serotonin reuptake inhibitors? Int Clin Psychopharmacol 10:215-220.
    • (1995) Int Clin Psychopharmacol , vol.10 , pp. 215-220
    • Park, S.B.G.1    Williamson, D.J.2    Cowen, P.J.3
  • 40
    • 0029820723 scopus 로고    scopus 로고
    • 5-HT neuroendocrine function in major depression: Prolactin and cortisol responses to D-fenfluramine
    • Park SBG, Williamson DJ, Cowne PJ (1996): 5-HT neuroendocrine function in major depression: Prolactin and cortisol responses to D-fenfluramine. Psychol Med 26:1191-1196.
    • (1996) Psychol Med , vol.26 , pp. 1191-1196
    • Park, S.B.G.1    Williamson, D.J.2    Cowne, P.J.3
  • 41
    • 0021737068 scopus 로고
    • New separation method for monoclonal immunoradiometric assays for thyrotropin and human choriogonadotropin
    • Rattle SJ, Purnell DR, Williams PIM, Siddle K, Forrest GC (1984): New separation method for monoclonal immunoradiometric assays for thyrotropin and human choriogonadotropin. Clin Chem 30:1457-1461.
    • (1984) Clin Chem , vol.30 , pp. 1457-1461
    • Rattle, S.J.1    Purnell, D.R.2    Williams, P.I.M.3    Siddle, K.4    Forrest, G.C.5
  • 42
    • 0021367903 scopus 로고
    • Plasma prolactin changes following fenfluramine in depressed patients compared to controls: An evaluation of central serotonergic responsivity in depression
    • Siever LJ, Murphy DL, Slater S, de la Vega E, Lipper S (1984): Plasma prolactin changes following fenfluramine in depressed patients compared to controls: An evaluation of central serotonergic responsivity in depression. Life Sci 34: 1029-1039.
    • (1984) Life Sci , vol.34 , pp. 1029-1039
    • Siever, L.J.1    Murphy, D.L.2    Slater, S.3    De La Vega, E.4    Lipper, S.5
  • 43
    • 0022387758 scopus 로고
    • Serotonergic stimulation of prolactin and corticosterone secretion is mediated by different pathways from the mediobasal hypothalamus
    • Van de Kar LD, Karteszi M, Bethea CL, Ganong WF (1985): Serotonergic stimulation of prolactin and corticosterone secretion is mediated by different pathways from the mediobasal hypothalamus. Neuroendocrinology 41:380-384.
    • (1985) Neuroendocrinology , vol.41 , pp. 380-384
    • Van De Kar, L.D.1    Karteszi, M.2    Bethea, C.L.3    Ganong, W.F.4
  • 44
    • 0022995996 scopus 로고
    • The pitfalls of serotonin precursors as challengers in hormonal probes of central serotonin activity
    • van Praag HM, Lemus C, Kahn R (1986): The pitfalls of serotonin precursors as challengers in hormonal probes of central serotonin activity. Psychopharmacol Bull 22:565-570.
    • (1986) Psychopharmacol Bull , vol.22 , pp. 565-570
    • Van Praag, H.M.1    Lemus, C.2    Kahn, R.3
  • 45
    • 0023879758 scopus 로고
    • Plasma cortisol, prolactin, growth hormone, and immunoreactive beta-endorphin response to fenfluramine challenge in depressed patients
    • Weizman A, Mark M, Gil Ad I, Tyano S, Laron Z (1988): Plasma cortisol, prolactin, growth hormone, and immunoreactive beta-endorphin response to fenfluramine challenge in depressed patients. Clin Neuropharmacol 11:250-256.
    • (1988) Clin Neuropharmacol , vol.11 , pp. 250-256
    • Weizman, A.1    Mark, M.2    Gil Ad., I.3    Tyano, S.4    Laron, Z.5
  • 46
    • 0023681619 scopus 로고
    • A structured interview guide for the hamilton depression rating scale
    • Williams J (1988): A structured interview guide for the Hamilton depression rating scale. Arch Gen Psychiatry 45:742-747.
    • (1988) Arch Gen Psychiatry , vol.45 , pp. 742-747
    • Williams, J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.