The mechanism of inhibition of topoisomerase IV by quinolone antibacterials

Journal of Biological Chemistry

Volumn 273, Issue 42, 1998, Pages 27668-27677

  Khodursky, Arkady B ^a,b   Cozzarelli, Nicholas R ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b STANFORD UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DETERGENT; DNA; DNA TOPOISOMERASE; NORFLOXACIN; PLASMID DNA; QUINOLINE DERIVED ANTIINFECTIVE AGENT;

ALLELE; ARTICLE; CELL DEATH; DNA ADDUCT; DNA CONTENT; DNA DAMAGE; DNA REPAIR; DNA REPLICATION; DNA SYNTHESIS; DRUG SENSITIVITY; ENZYME ACTIVITY; ENZYME INHIBITION; ESCHERICHIA COLI; FLOW CYTOMETRY; GENE MUTATION; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PRIORITY JOURNAL;

ADENOSINE TRIPHOSPHATASES; ANTI-INFECTIVE AGENTS; CHROMOSOMES, BACTERIAL; DNA ADDUCTS; DNA DAMAGE; DNA HELICASES; DNA REPAIR; DNA REPLICATION; DNA TOPOISOMERASE IV; DNA TOPOISOMERASES, TYPE II; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; EXODEOXYRIBONUCLEASE V; EXODEOXYRIBONUCLEASES; MODELS, GENETIC; MUTATION; NORFLOXACIN; PLASMIDS; PROTEIN BINDING; REC A RECOMBINASES; SOS RESPONSE (GENETICS);

ESCHERICHIA COLI;

EID: 0032538454     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.273.42.27668     Document Type: Article

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