Synthesis and ligand binding of tropane ring analogues of paroxetine

Journal of Medicinal Chemistry

Volumn 41, Issue 2, 1998, Pages 247-257

  Keverline Frantz, Kathryn I ^a,c   Boja, John W ^b,d   Kuhar, Michael J ^b,e   Abraham, Philip ^a   Burgess, Jason P ^a   Lewin, Anita H ^a   Carroll, F Ivy ^a  

^a RTI INTERNATIONAL   (United States)

^b NATIONAL INSTITUTE ON DRUG ABUSE   (United States)

^c Delaware Valley College   (United States)

^d NORTHEAST OHIO MEDICAL UNIVERSITY   (United States)

^e EMORY UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 (4 FLUOROPHENYL) 2 [[3,4 (METHYLENEDIOXY)PHENOXY]METHYL]NORTROPANE; PAROXETINE; SEROTONIN TRANSPORTER; SEROTONIN UPTAKE INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; BINDING SITE; DATA ANALYSIS; DRUG SYNTHESIS; ISOMERISM; LIGAND BINDING; PROTEIN CONFORMATION; STEREOCHEMISTRY;

BINDING, COMPETITIVE; COCAINE; DOPAMINE UPTAKE INHIBITORS; ISOMERISM; LIGANDS; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, CHEMICAL; MODELS, MOLECULAR; PAROXETINE; RECEPTORS, SEROTONIN; SEROTONIN UPTAKE INHIBITORS; STRUCTURE-ACTIVITY RELATIONSHIP; TROPANES;

EID: 0031893483     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm970669p     Document Type: Article

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