2β-substituted analogues of 4'-iodococaine: Synthesis and dopamine transporter binding potencies

Journal of Medicinal Chemistry

Volumn 41, Issue 13, 1998, Pages 2380-2389

  Avor, Kwasi S ^a   Singh, Satendra ^a   Seale, Thomas W ^b   Pouw, Buddy ^a   Basmadjian, Garo P ^a  

^a UNIVERSITY OF OKLAHOMA   (United States)

^b UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 [2 (BENZHYDRYLOXY)ETHYL] 4 (3 PHENYLPROPYL)PIPERAZINE; 3BETA (4 FLUOROPHENYL) 2BETA TROPANECARBOXYLIC ACID METHYL ESTER; 4' IODOCOCAINE; BENZOYLECGONINE; COCAINE DERIVATIVE; ECGONINE METHYL ESTER; IMIDAZOLE DERIVATIVE; NISOXETINE; NORADRENALIN DERIVATIVE; SEROTONIN TRANSPORTER; UNCLASSIFIED DRUG; 3 ((2' HYDROXY 4' IODOBENZOYL)OXY) 8 METHYL 8 AZABICYCLO(3.2.1)OCTANE 2 CARBOXYLIC ACID ISOPROPYL ESTER; 3-((2'-HYDROXY-4'-IODOBENZOYL)OXY)-8-METHYL-8-AZABICYCLO(3.2.1)OCTANE-2-CARBOXYLIC ACID ISOPROPYL ESTER; 4'-IODOCOCAINE; CARRIER PROTEIN; CENTRAL STIMULANT AGENT; COCAINE; DOPAMINE TRANSPORTER; DRUG DERIVATIVE; MEMBRANE PROTEIN; NERVE PROTEIN; SLC6A3 PROTEIN, MOUSE; SLC6A3 PROTEIN, RAT;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DOPAMINE UPTAKE; DRUG BINDING; DRUG HYDROLYSIS; DRUG HYDROXYLATION; DRUG POTENCY; DRUG SELECTIVITY; DRUG SYNTHESIS; INTRAPERITONEAL DRUG ADMINISTRATION; LOCOMOTION; MALE; MOUSE; NONHUMAN; RAT; ANIMAL; BRAIN; C57BL MOUSE; DRUG EFFECT; METABOLISM; MOTOR ACTIVITY; PROTEIN BINDING; SPRAGUE DAWLEY RAT; SYNTHESIS;

ANIMALS; BRAIN; CARRIER PROTEINS; CENTRAL NERVOUS SYSTEM STIMULANTS; COCAINE; DOPAMINE PLASMA MEMBRANE TRANSPORT PROTEINS; MALE; MEMBRANE GLYCOPROTEINS; MEMBRANE TRANSPORT PROTEINS; MICE; MICE, INBRED C57BL; MOTOR ACTIVITY; NERVE TISSUE PROTEINS; PROTEIN BINDING; RATS; RATS, SPRAGUE-DAWLEY;

EID: 0032543297     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm980061w     Document Type: Article

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