Synthesis, structure, dopamine transporter affinity, and dopamine uptake inhibition of 6-alkyl-3-benzyl-2-[(methoxycarbonyl)methyl]tropane derivatives

Journal of Medicinal Chemistry

Volumn 40, Issue 26, 1997, Pages 4406-4414

  Lomenzo, Stacey A ^a   Izenwasser, Sari ^b   Katz, Jonathan L ^b   Terry, Phyllis D ^b   Zhu, Naijue ^c   Klein, Cheryl L ^c   Trudell, Mark L ^a  

^a UNIVERSITY OF NEW ORLEANS   (United States)

^b NATIONAL INSTITUTE ON DRUG ABUSE   (United States)

^c XAVIER UNIVERSITY OF LOUISIANA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3BETA (4 FLUOROPHENYL) 2BETA TROPANECARBOXYLIC ACID METHYL ESTER; 3BETA BENZYL 2ALPHA[(METHOXYCARBONYL)METHYL] 8 METHYL 8 AZABICYCLO[3.2.1]OCTANE; 3BETA BENZYL 2BETA [(METHOXYCARBONYL)METHYL] 8 METHYL8 AZABICYCLO[3.2.1]OCTANE; COCAINE; DOPAMINE RECEPTOR BLOCKING AGENT; DOPAMINE TRANSPORTER; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; BINDING SITE; DOPAMINE RELEASE; DOPAMINERGIC ACTIVITY; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; STRUCTURE ACTIVITY RELATION;

ANIMALS; BINDING SITES; BINDING, COMPETITIVE; BRAIN; CARRIER PROTEINS; COCAINE; DOPAMINE; DOPAMINE PLASMA MEMBRANE TRANSPORT PROTEINS; DOPAMINE UPTAKE INHIBITORS; MAGNETIC RESONANCE SPECTROSCOPY; MEMBRANE GLYCOPROTEINS; MEMBRANE TRANSPORT PROTEINS; MOLECULAR STRUCTURE; NERVE TISSUE PROTEINS; RATS; TROPANES;

EID: 0031450277     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm970549h     Document Type: Article

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