2-carbomethoxy-3-aryl-8-oxabicyclo[3.2.1]octanes: Potent non-nitrogen inhibitors of monoamine transporters

Journal of Medicinal Chemistry

Volumn 40, Issue 17, 1997, Pages 2661-2673

  Meltzer, Peter C ^a   Liang, Anna Y ^a   Blundell, Paul ^a   Gonzalez, Mario D ^a   Chen, Zhengming ^a   George, Clifford ^b   Madras, Bertha K ^c  

^a ORGANIX INC   (United States)

^b NAVAL RESEARCH LABORATORY   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2BETA CARBOMETHOXY 3ALPHA (3,4,DICHLOROPHENYL) 8 OXABICYCLO[3.2.1]OCTANE; 2BETA CARBOMETHOXY 3BETA (3,4 DICHLOROPHENYL) 8 OXABICYCLO[3.2.1]OCTANE; 3BETA (4 FLUOROPHENYL) 2BETA TROPANECARBOXYLIC ACID METHYL ESTER; CITALOPRAM; DOPAMINE UPTAKE INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; DRUG PROTEIN BINDING; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; STRUCTURE ANALYSIS;

ANIMALS; BINDING, COMPETITIVE; BIOLOGICAL TRANSPORT; CARRIER PROTEINS; CAUDATE NUCLEUS; CITALOPRAM; DOPAMINE PLASMA MEMBRANE TRANSPORT PROTEINS; DOPAMINE UPTAKE INHIBITORS; FEMALE; LIGANDS; MACACA FASCICULARIS; MALE; MEMBRANE GLYCOPROTEINS; MEMBRANE TRANSPORT PROTEINS; MODELS, CHEMICAL; MODELS, MOLECULAR; NERVE TISSUE PROTEINS; OCTANES; PUTAMEN; SEROTONIN PLASMA MEMBRANE TRANSPORT PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP; TROPANES;

EID: 0030837830     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm9703045     Document Type: Article

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