-
2
-
-
0025775062
-
Scudiero, D.; Skehan, P.; Shoemaker, R.; P.aull, K.; Vistica, D.; Hose, C.; Langley, J.; Cronise, P.; Vaigrowolff, A.; Gray-Goodrich, M.; Campbell, H.; Mayo, J.; Boyd, M
-
1991.
-
Monks, A.; Scudiero, D.; Skehan, P.; Shoemaker, R.; P.aull, K.; Vistica, D.; Hose, C.; Langley, J.; Cronise, P.; Vaigrowolff, A.; Gray-Goodrich, M.; Campbell, H.; Mayo, J.; Boyd, M. Feasibility of a high-flux anticancer drug screen using a diverse panel of cultured human tumor cell lines. J. Natl. Cancer. Inst. 83:757-766; 1991.
-
Feasibility of A High-flux Anticancer Drug Screen Using A Diverse Panel of Cultured Human Tumor Cell Lines. J. Natl. Cancer. Inst. 83:757-766
-
-
Monks, A.1
-
3
-
-
0028049743
-
W.; Kraker, A
-
1994.
-
Fry, D. W.; Kraker, A. J.; Gönners, R. C.; Elliott, W. L.; Nelson, J. M.; Showalter, H. D. H.; Leopold, W. R. Strategies for the discovery of novel tyrosine kinase inhibitors with anticancer activity. Anticancer Drug Design 9:331-351; 1994.
-
J.; Gönners, R. C.; Elliott, W. L.; Nelson, J. M.; Showalter, H. D. H.; Leopold, W. R. Strategies for the Discovery of Novel Tyrosine Kinase Inhibitors with Anticancer Activity. Anticancer Drug Design 9:331-351
-
-
Fry, D.1
-
4
-
-
44149089022
-
K.; Reed, S
-
1998.
-
Vogt, P. K.; Reed, S. I., eds. Current topics in microbiology and immunology, 227: Cyclin dependent kinase (CDK) inhibitors, 1st ed. Berlin: Springer; 1998.
-
I., Eds. Current Topics in Microbiology and Immunology, 227: Cyclin Dependent Kinase (CDK) Inhibitors, 1st Ed. Berlin: Springer
-
-
Vogt, P.1
-
5
-
-
0023717342
-
D.; McNally, N
-
1988.
-
Wilson, G. D.; McNally, N. J.; Dische, S.; Saunders, M. L; Des Rochers, C.; Lewis, A. A.; Bennett, M. H. Measurement of cell kinetics in human tumours in vivo using bromodeoxyuridine incorporation and flow cytometry. Br. J. Cancer 58:423-431; 1988.
-
J.; Dische, S.; Saunders, M. L; des Rochers, C.; Lewis, A. A.; Bennett, M. H. Measurement of Cell Kinetics in Human Tumours in Vivo Using Bromodeoxyuridine Incorporation and Flow Cytometry. Br. J. Cancer 58:423-431
-
-
Wilson, G.1
-
7
-
-
0031028730
-
Rodriguez-Viciana, P.; Ulrich, E.; Gilbert, C.; Coffer, P.; Downward, J.; Evan, G
-
1997.
-
Kauffmanzeh, A.; Rodriguez-Viciana, P.; Ulrich, E.; Gilbert, C.; Coffer, P.; Downward, J.; Evan, G. Suppression of C-myc-induced apoptosis by ras signalling through PI(3)K and PKB. Nature 385:544-548; 1997.
-
Suppression of C-myc-induced Apoptosis by Ras Signalling Through PI(3)K and PKB. Nature 385:544-548
-
-
Kauffmanzeh, A.1
-
14
-
-
0030026679
-
E.; Leung-Hagesteijn, C.; Fitz-Gibbon, L.; Coppolino, M
-
1996.
-
Hannigan, G. E.; Leung-Hagesteijn, C.; Fitz-Gibbon, L.; Coppolino, M. G.; Radeva, G.; Filmus, J.; Bell, J. C.; Dedhar, S. Regulation of cell adhesion and anchorage-dependent growth by a new beta 1-integrin-linked protein kinase. Nature 379:91-96; 1996.
-
G.; Radeva, G.; Filmus, J.; Bell, J. C.; Dedhar, S. Regulation of Cell Adhesion and Anchorage-dependent Growth by A New Beta 1-integrin-linked Protein Kinase. Nature 379:91-96
-
-
Hannigan, G.1
-
16
-
-
0018144586
-
D.; Selby, P
-
1978.
-
Courtenay, V. D.; Selby, P. J.; Smith, I. E.; Mills, J.; Peckham, M. J. Growth of human tumour cell colonies from biopsies using two soft-agar techniques. Br. J. Cancer 38:77-81; 1978.
-
J.; Smith, I. E.; Mills, J.; Peckham, M. J. Growth of Human Tumour Cell Colonies from Biopsies Using Two Soft-agar Techniques. Br. J. Cancer 38:77-81
-
-
Courtenay, V.1
-
19
-
-
0025830413
-
Apoptosis, intrinsic radiosensitivity and prediction of radiotherapy response in cervical carcinoma
-
1991.
-
West, C. M. L.; Davidson, S. E.; Hendry, J. H.; Hunter, R. D. Prediction of cervical carcinoma response to radiotherapy. Lancet 338:818; 1991.
-
radiotherapy and oncology
-
-
West, C.1
-
20
-
-
0025968045
-
D.; Kronmal, R.; Salmon, S
-
1991.
-
Von Hoff, D. D.; Kronmal, R.; Salmon, S. E.; Turner, J.; Green, J. B.; Bonorris, J. S.; Moorhead, E. L.; Hynes, H. E.; Pugh, R. E.; Belt, R. J.; Alberts, D. S. A Southwest Oncology Group study on the use of a human tumor cloning assay for predicting response iii patients with ovarian cancer. Cancer 67:20-27; 1991.
-
E.; Turner, J.; Green, J. B.; Bonorris, J. S.; Moorhead, E. L.; Hynes, H. E.; Pugh, R. E.; Belt, R. J.; Alberts, D. S. A Southwest Oncology Group Study on the Use of A Human Tumor Cloning Assay for Predicting Response Iii Patients with Ovarian Cancer. Cancer 67:20-27
-
-
Von Hoff, D.1
-
24
-
-
44149117673
-
-
1992:55-85.
-
Finlay, G. J. In vitro systems for anti-cancer drug screening. In: Waring, M. J.; Ponder, B. A., eds. The search for new anti-cancer drugs, 1st ed. Dordrecht: Kluwer; 1992:55-85.
-
In Vitro Systems for Anti-cancer Drug Screening. In: Waring, M. J.; Ponder, B. A., Eds. the Search for New Anti-cancer Drugs, 1st Ed. Dordrecht: Kluwer
-
-
Finlay, G.1
-
25
-
-
0031747832
-
West, C
-
2371-2375; 1998.
-
Bjork-Eriksson, T.; West, C. M. L.; Karlsson, E.; Slevin, N. J.; Davidson, S. E.; James, R. D.; Mercke, C. The in vitro radiosensitivity of human head and neck cancers. Br. J. Cancer 77:2371-2375; 1998.
-
M. L.; Karlsson, E.; Slevin, N. J.; Davidson, S. E.; James, R. D.; Mercke, C. the in Vitro Radiosensitivity of Human Head and Neck Cancers. Br. J. Cancer 77
-
-
Bjork-Eriksson, T.1
-
27
-
-
0030842655
-
Zhang, y
-
1034-1036; 1997.
-
Waldman, T.; Zhang, Y. G.; Dillehay, L.; Yu, J.; Kinzler, K.; Vogelstein, B.; Williams, J. Cell-cycle arrest versus cell death in cancer therapy. Nat. Med. 3:1034-1036; 1997.
-
G.; Dillehay, L.; Yu, J.; Kinzler, K.; Vogelstein, B.; Williams, J. Cell-cycle Arrest Versus Cell Death in Cancer Therapy. Nat. Med. 3
-
-
Waldman, T.1
-
28
-
-
0026602982
-
S.; Finlay, G
-
1992.
-
Marshall, E. S.; Finlay, G. J.; Matthews, J. H. L.; Shaw, J. H. F.; Nixon, J.; Baguley, B. C. Microculture-bascd chemosensitivity testing: A feasibility study comparing freshly explanted human melanoma cells with human melanoma cell lines. J. Nail. Cancer. Inst. 84:340-345; 1992.
-
J.; Matthews, J. H. L.; Shaw, J. H. F.; Nixon, J.; Baguley, B. C. Microculture-bascd Chemosensitivity Testing: A Feasibility Study Comparing Freshly Explanted Human Melanoma Cells with Human Melanoma Cell Lines. J. Nail. Cancer. Inst. 84:340-345
-
-
Marshall, E.1
-
29
-
-
0032101824
-
C.; Marshall, e
-
1086-1090; 1998.
-
Baguley, B. C.; Marshall, E. S.; Holdaway, K. M.; Rewcastle, G. W.; Denny, W. A. Inhibition of growth of primary human tumour cell cultures by a 4-aniIinoquinazoline inhibitor of the epidermal growth factor receptor family of tyrosine kinases. Eur. J. Cancer 34:1086-1090; 1998.
-
S.; Holdaway, K. M.; Rewcastle, G. W.; Denny, W. A. Inhibition of Growth of Primary Human Tumour Cell Cultures by A 4-aniIinoquinazoline Inhibitor of the Epidermal Growth Factor Receptor Family of Tyrosine Kinases. Eur. J. Cancer 34
-
-
Baguley, B.1
-
31
-
-
0025125820
-
F.; Steinbcrg, S
-
1990.
-
Gazdar, A. F.; Steinbcrg, S. M.; Russell, E. K.; Linnoila, R. I.; Oie, H. K.; Ghosh, B. C; Cotelingam, J. D.; Johnson, B. E.: Minna, J. D.; Ihde, D. C. Correlation of in vitro drug-sensitivity testing results with response to chemotherapy and survival in extensive-stage small cell lung cancer: A prospective clinical trial. J. Natl. Cancer. Inst. 82:117-124; 1990.
-
M.; Russell, E. K.; Linnoila, R. I.; Oie, H. K.; Ghosh, B. C; Cotelingam, J. D.; Johnson, B. E.: Minna, J. D.; Ihde, D. C. Correlation of in Vitro Drug-sensitivity Testing Results with Response to Chemotherapy and Survival in Extensive-stage Small Cell Lung Cancer: A Prospective Clinical Trial. J. Natl. Cancer. Inst. 82:117-124
-
-
Gazdar, A.1
-
32
-
-
0022550431
-
L.; Spitzer, G.; Ajani, J
-
1263-1274; 1986.
-
Baker, F. L.; Spitzer, G.; Ajani, J. A.; Brock, W. A.; Lukcman, J.; Pathak, S.; Tomasovic, B.; Thielvoldt, D.; Williams, M.; Vines, C.; Tofilon, P. Drug and radiation sensitivity measurements of successful primary monolayer culturing of human tumour cells using cell-adhesive matrix and supplemented medium. Cancer Res. 46:1263-1274; 1986.
-
A.; Brock, W. A.; Lukcman, J.; Pathak, S.; Tomasovic, B.; Thielvoldt, D.; Williams, M.; Vines, C.; Tofilon, P. Drug and Radiation Sensitivity Measurements of Successful Primary Monolayer Culturing of Human Tumour Cells Using Cell-adhesive Matrix and Supplemented Medium. Cancer Res. 46
-
-
Baker, F.1
-
34
-
-
0027395776
-
Lubin, R.; Pignon, J
-
1993.
-
Girinsky, T.; Lubin, R.; Pignon, J. P.; Chavaudra, N.; Gazeau, J.; Dubray, B.; Cosset, J. M.; Socie, G.; Fertil, B. Predictive value of in vitro radiosensitivity parameters in head and neck cancers and cervical carcinomas: Preliminary correlations with local control and overall survival. Int. J. Radiât. Oncol. Biol. Phys. 25:3-7; 1993.
-
P.; Chavaudra, N.; Gazeau, J.; Dubray, B.; Cosset, J. M.; Socie, G.; Fertil, B. Predictive Value of in Vitro Radiosensitivity Parameters in Head and Neck Cancers and Cervical Carcinomas: Preliminary Correlations with Local Control and Overall Survival. Int. J. Radiât. Oncol. Biol. Phys. 25:3-7
-
-
Girinsky, T.1
-
35
-
-
0029763896
-
Kitaoka, A.; Yamakawa, M.; Tanisaka, K.; Kobayashi, H
-
1925-1930; 1996.
-
Tanigawa, N.; Kitaoka, A.; Yamakawa, M.; Tanisaka, K.; Kobayashi, H. In vitro chemosensitivity testing of human tumours by collagen gel droplet culture and image analysis. Anticancer Res. 16:1925-1930; 1996.
-
In Vitro Chemosensitivity Testing of Human Tumours by Collagen Gel Droplet Culture and Image Analysis. Anticancer Res. 16
-
-
Tanigawa, N.1
-
36
-
-
0030984734
-
Stunz, L
-
1997.
-
Kovar, J.; Stunz, L. L.; Stewart, B. C.; Kriegerbeckova, K.; Ashman, R. F.; Kemp, J. D. Direct evidence that iron deprivation induces apoptosis in murine lymphoma 38C13. Pathobiology 65: 61-68; 1997.
-
L.; Stewart, B. C.; Kriegerbeckova, K.; Ashman, R. F.; Kemp, J. D. Direct Evidence That Iron Deprivation Induces Apoptosis in Murine Lymphoma 38C13. Pathobiology 65: 61-68
-
-
Kovar, J.1
-
37
-
-
0029741901
-
Raab, B.; Maurer, S.; Rosick, U.; Brigelius-Flohe, R
-
1996.
-
Leist, M.; Raab, B.; Maurer, S.; Rosick, U.; Brigelius-Flohe, R. Conventional cell culture media do not adequately supply cells with antioxidants and thus facilitate peroxide-induced genotoxicity. Free Radie. Biol. Med. 21:297-306; 1996.
-
Conventional Cell Culture Media Do Not Adequately Supply Cells with Antioxidants and Thus Facilitate Peroxide-induced Genotoxicity. Free Radie. Biol. Med. 21:297-306
-
-
Leist, M.1
-
38
-
-
0022654024
-
Carney, D
-
1986.
-
Brower, M.; Carney, D. N.; Oie, H. K.; Gazdar, A. F.; Minna, J. D. Growth of cell lines and clinical specimens of human nonsmall cell lung cancer in a serum-free defined medium. Cancer Res. 46:798-806; 1986.
-
N.; Oie, H. K.; Gazdar, A. F.; Minna, J. D. Growth of Cell Lines and Clinical Specimens of Human Nonsmall Cell Lung Cancer in A Serum-free Defined Medium. Cancer Res. 46:798-806
-
-
Brower, M.1
-
40
-
-
4244006599
-
F.; Stefan, C.; Nobel, I.; van den Dobbelsteen, D
-
1995.
-
Slater, A. F.; Stefan, C.; Nobel, I.; van den Dobbelsteen, D. J.; Orrenius, S. Signalling mechanisms and oxidative stress in apoptosis. Toxicol. Lett. 82-83:149-153; 1995.
-
J.; Orrenius, S. Signalling Mechanisms and Oxidative Stress in Apoptosis. Toxicol. Lett. 82-83:149-153
-
-
Slater, A.1
-
42
-
-
0025341331
-
Storeng, R.; Scudiero, D.; Monks, A.; McMahon, J.; Vistica, D.; Warren, J
-
1107-1112; 1990.
-
Skehan, P.; Storeng, R.; Scudiero, D.; Monks, A.; McMahon, J.; Vistica, D.; Warren, J. T.; Bokesch, H.; Kenney, S.; Boyd, M. R. New colorimetric cytotoxicity assay for anlicancer-drug screening. J. Nail. Cancer Inst. 82:1107-1112; 1990.
-
T.; Bokesch, H.; Kenney, S.; Boyd, M. R. New Colorimetric Cytotoxicity Assay for Anlicancer-drug Screening. J. Nail. Cancer Inst. 82
-
-
Skehan, P.1
-
43
-
-
0021061819
-
Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
-
1983.
-
Mosmann, T. Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays. J. Immunol. Methods 65:55-63; 1983.
-
J. Immunol. Methods 65:55-63
-
-
Mosmann, T.1
-
45
-
-
0023792919
-
A.; Shoemaker, R
-
4827-4833; 1988.
-
Scudiero, D. A.; Shoemaker, R. H.; Paull, K. D.; Monks, A.; Tierney, S.; Nofziger, T. H.; Currens, M. J.; Seniff, D.; Boyd, M. R. Evaluation of a soluble tetrazolium/formazan assay for cell growth and drug sensitivity in culture using human and other tumour cell lines. Cancer Res. 48:4827-4833; 1988.
-
H.; Paull, K. D.; Monks, A.; Tierney, S.; Nofziger, T. H.; Currens, M. J.; Seniff, D.; Boyd, M. R. Evaluation of A Soluble Tetrazolium/formazan Assay for Cell Growth and Drug Sensitivity in Culture Using Human and Other Tumour Cell Lines. Cancer Res. 48
-
-
Scudiero, D.1
-
46
-
-
0025294320
-
K.; Sargent, J
-
1990.
-
Wilson, J. K.; Sargent, J. M.; Elgie, A. W.; Hill, J. G.; Taylor, C. G. A feasibility study of the MTT assay for chemosensitivity testing in ovarian malignancy. Br. J. Cancer 62:189-194; 1990.
-
M.; Elgie, A. W.; Hill, J. G.; Taylor, C. G. A Feasibility Study of the MTT Assay for Chemosensitivity Testing in Ovarian Malignancy. Br. J. Cancer 62:189-194
-
-
Wilson, J.1
-
49
-
-
0024273710
-
K.; Hurst, T.; Webb, M
-
1988.
-
Khoo, S. K.; Hurst, T.; Webb, M. J.; Dickie, G.; Kearsley, J.; Parsons, P. G.; Mackay, E. V. Cisplatin chemotherapy of ovarian cancer: Is short-term in vitro chemosensitivity predictive of longterm patient survival? Aust. N. Z. J. Obstet. Gynaecol. 28:313-317; 1988.
-
J.; Dickie, G.; Kearsley, J.; Parsons, P. G.; Mackay, E. V. Cisplatin Chemotherapy of Ovarian Cancer: Is Short-term in Vitro Chemosensitivity Predictive of Longterm Patient Survival? Aust. N. Z. J. Obstet. Gynaecol. 28:313-317
-
-
Khoo, S.1
-
51
-
-
0028904536
-
C.; Marshall, e
-
1995.
-
Baguley, B. C.; Marshall, E. S.; Whiltaker, J. R.; Dotchin, M. C; Nixon, J.; McCrystal, M. R.; Finlay, G. J.; Matthews, J. H. L.; Holdaway, K. M.; van Zijl, P. Resistance mechanisms determining the in vitro sensitivity to paclitaxcl of tumour cells cultured from patients with ovarian cancer. Eur. J. Cancer 3IA:230-237; 1995.
-
S.; Whiltaker, J. R.; Dotchin, M. C; Nixon, J.; McCrystal, M. R.; Finlay, G. J.; Matthews, J. H. L.; Holdaway, K. M.; Van Zijl, P. Resistance Mechanisms Determining the in Vitro Sensitivity to Paclitaxcl of Tumour Cells Cultured from Patients with Ovarian Cancer. Eur. J. Cancer 3IA:230-237
-
-
Baguley, B.1
-
56
-
-
0030020158
-
A.; Wendeil, K.; Gardiner, S.; Deny, W
-
1996.
-
Jordan, M. A.; Wendeil, K.; Gardiner, S.; Deny, W. B.; Copp, H.; Wilson, L. Mitotic block induced in HeLa cells by low concentrations of paclitaxel (taxol) results in abnormal mitotic exit and apoptotic cell death. Cancer Res. 56:816-825; 1996.
-
B.; Copp, H.; Wilson, L. Mitotic Block Induced in HeLa Cells by Low Concentrations of Paclitaxel (Taxol) Results in Abnormal Mitotic Exit and Apoptotic Cell Death. Cancer Res. 56:816-825
-
-
Jordan, M.1
-
60
-
-
0029130763
-
W.; Denny, W
-
3482-3487; 1995.
-
Rewcastle, G. W.; Denny, W. A.; Bridges, A. J.; Zhou, H. R.; Cody, D. R.; McMichael, A.; Fry, D. \V. Tyrosine kinase inhibitors. 5. Synthesis and structure-activity relationships for 4-((phenylmethyl)amino)- and 4-(phenyIamino)quinazolines as potent adenosine 5'-triphosphate binding site inhibitors of the tyrosine kinase domain of the epidermal growth factor receptor. J. Med. Chem. 38:3482-3487; 1995.
-
A.; Bridges, A. J.; Zhou, H. R.; Cody, D. R.; McMichael, A.; Fry, D. \V. Tyrosine Kinase Inhibitors. 5. Synthesis and Structure-activity Relationships for 4-((phenylmethyl)amino)- and 4-(phenyIamino)quinazolines As Potent Adenosine 5'-triphosphate Binding Site Inhibitors of the Tyrosine Kinase Domain of the Epidermal Growth Factor Receptor. J. Med. Chem. 38
-
-
Rewcastle, G.1
-
61
-
-
0030039555
-
J.; Zhou, H.; Cody, D
-
153035, a potent inhibitor of the epidermal growth factor receptor. J. Med. Chem. 39:267-276; 1996.
-
Bridges, A. J.; Zhou, H.; Cody, D. R.; Rewcastle, G. W.; McMichael, A.; Showalter, H. D.; Fry, D. W.; Kraker, A. J.; Denny, W. A. Tyrosine kinase inhibitors. 8. An unusually steep structure-activity relationship for analogues of 4-(3-bromoanilino)-6,7-dimelhoxyquinazoline (PD 153035), a potent inhibitor of the epidermal growth factor receptor. J. Med. Chem. 39:267-276; 1996.
-
R.; Rewcastle, G. W.; McMichael, A.; Showalter, H. D.; Fry, D. W.; Kraker, A. J.; Denny, W. A. Tyrosine Kinase Inhibitors. 8. An Unusually Steep Structure-activity Relationship for Analogues of 4-(3-bromoanilino)-6,7-dimelhoxyquinazoline PD
-
-
Bridges, A.1
-
63
-
-
0030930366
-
Xia, Y.; Zweier, J
-
1997.
-
Polyak, K.; Xia, Y.; Zweier, J. L.; Kinzler, K. W.; Vogelstein, B. A model for p53-induced apoptosis. Nature 389:300-305; 1997.
-
L.; Kinzler, K. W.; Vogelstein, B. A Model for P53-induced Apoptosis. Nature 389:300-305
-
-
Polyak, K.1
-
64
-
-
0024988359
-
Activation of programmed cell death by anticancer agents: Cisplatin as a model system
-
1990.
-
Eastman, A. Activation of programmed cell death by anticancer agents: Cisplatin as a model system. Cancer Cells 2:275-280; 1990.
-
Cancer Cells 2:275-280
-
-
Eastman, A.1
-
65
-
-
8944263468
-
Giarola, M.; Righelti, S
-
1996.
-
Perego, P.; Giarola, M.; Righelti, S. C; Supino, R.; Caserini, C; Delia, D.; Pierotti, M. A.; Miyashita, T.; Reed, J. C.; Zunino, F. Association between cisplatin resistance and mutation of p53 gene and reduced bax expression in ovarian carcinoma cell systems. Cancer Res. 56:556-562; 1996.
-
C; Supino, R.; Caserini, C; Delia, D.; Pierotti, M. A.; Miyashita, T.; Reed, J. C.; Zunino, F. Association between Cisplatin Resistance and Mutation of P53 Gene and Reduced Bax Expression in Ovarian Carcinoma Cell Systems. Cancer Res. 56:556-562
-
-
Perego, P.1
-
67
-
-
0026687883
-
P.; Sakaguchi, K.; Ullrich, S
-
5041-5049; 1992.
-
Lees-Miller, S. P.; Sakaguchi, K.; Ullrich, S. J.; Appella, E.; Anderson, C. W. Human DNA-activated protein kinase phosphorylates serine-15 and serine-37 in the amino-terminal transactivation domain of human p53. Mol. Cell Biol. 12:5041-5049; 1992.
-
J.; Appella, E.; Anderson, C. W. Human DNA-activated Protein Kinase Phosphorylates Serine-15 and Serine-37 in the Amino-terminal Transactivation Domain of Human P53. Mol. Cell Biol. 12
-
-
Lees-Miller, S.1
-
68
-
-
0032514485
-
A.; McLure, K
-
1998.
-
Woo, R. A.; McLure, K. G.; Leesmiller, S. P.; Rancourt, D. E.; Lee, P. \V. K. DNA-dependent protein kinase acts upstream of p53 in response to DNA damage. Nature 394:700-704; 1998.
-
G.; Leesmiller, S. P.; Rancourt, D. E.; Lee, P. \V. K. DNA-dependent Protein Kinase Acts Upstream of P53 in Response to DNA Damage. Nature 394:700-704
-
-
Woo, R.1
-
69
-
-
0026318356
-
B.; Onyekwere, O.; Sidransky, D.; Vogelstein, B.; Craig, R
-
6304-6311; 1991.
-
Kastan, M. B.; Onyekwere, O.; Sidransky, D.; Vogelstein, B.; Craig, R. W. Participation of p53 protein in the cellular response to DNA damage. Cancer Res. 51:6304-6311; 1991.
-
W. Participation of P53 Protein in the Cellular Response to DNA Damage. Cancer Res. 51
-
-
Kastan, M.1
-
71
-
-
0032522463
-
S.; Burns, T
-
1593-1598; 1998.
-
Sheikh, M. S.; Burns, T. F.; Huang, Y.; Wu, G. S.; Amundson, S.; Brooks, K. S.; Fornace, A. J.; Eldeiry, W. S. P53-dependcnt and -independent regulation of the death receptor KILLER/DR5 gene expression in response to genotoxic stress and tumor necrosis factor o. Cancer Res. 58:1593-1598; 1998.
-
F.; Huang, Y.; Wu, G. S.; Amundson, S.; Brooks, K. S.; Fornace, A. J.; Eldeiry, W. S. P53-dependcnt and -Independent Regulation of the Death Receptor KILLER/DR5 Gene Expression in Response to Genotoxic Stress and Tumor Necrosis Factor O. Cancer Res. 58
-
-
Sheikh, M.1
-
73
-
-
0028294605
-
S.; Harper, J
-
1169-1174; 1994.
-
El-Deiry, W. S.; Harper, J. W.; O'Connor, P. M.; Velculescu, V. E.; Canman, C. E.; Jackman, J.; Pietenpol, J. A.; Burrell, M.; Hill, D. E.; Wang, Y. S.; Wiman, K. G.; Mercer, W. E.; Kastan, M. B.; Kohn, K. W.; Elledge, S. J.; Kinzler, K. W.; Vogelstein, B. Wafl/ cipl is induced in p53-mediated Gl arrest and apoptosis. Cancer Res. 54:1169-1174; 1994.
-
W.; O'Connor, P. M.; Velculescu, V. E.; Canman, C. E.; Jackman, J.; Pietenpol, J. A.; Burrell, M.; Hill, D. E.; Wang, Y. S.; Wiman, K. G.; Mercer, W. E.; Kastan, M. B.; Kohn, K. W.; Elledge, S. J.; Kinzler, K. W.; Vogelstein, B. Wafl/ Cipl Is Induced in P53-mediated Gl Arrest and Apoptosis. Cancer Res. 54
-
-
El-Deiry, W.1
-
74
-
-
0032553485
-
Dutriaux, A.; Waldman, T.; Zhou, S.; Brown, J
-
1497-1501; 1998.
-
Bunz, F.; Dutriaux, A.; Waldman, T.; Zhou, S.; Brown, J. P.; Sedivy, J. M.; Kinzler, K. W.; Vogelstein, B. Requirement of p53 and p21 to sustain G2 arrest after DNA damage. Science 282:1497-1501; 1998.
-
P.; Sedivy, J. M.; Kinzler, K. W.; Vogelstein, B. Requirement of P53 and P21 to Sustain G2 Arrest after DNA Damage. Science 282
-
-
Bunz, F.1
-
75
-
-
0029964158
-
P.; Clarkin, K
-
1996.
-
Linke, S. P.; Clarkin, K. C.; Dileonardo, A.; Tsou, A.; Wahl, G. M. A reversible, p53-dependent GJGi cell cycle arrest induced by ribonucleotide depletion in the absence of detectable DNA damage. Genes Dev. 10:934-947; 1996.
-
C.; Dileonardo, A.; Tsou, A.; Wahl, G. M. A Reversible, P53-dependent GJGi Cell Cycle Arrest Induced by Ribonucleotide Depletion in the Absence of Detectable DNA Damage. Genes Dev. 10:934-947
-
-
Linke, S.1
-
78
-
-
0025922083
-
Labbe, J
-
1991.
-
Strausfeld, U.; Labbe, J. C.; Fesquet, D.; Cavadore, J. C.; Picard, A.; Sadhu, K.; Russell, P.; Dorée, M. Dephosphorylation and activation of a p34cdc2 cyclin-B complex in vitro by human cdc25 protein. Nature 351:242-245; 1991.
-
C.; Fesquet, D.; Cavadore, J. C.; Picard, A.; Sadhu, K.; Russell, P.; Dorée, M. Dephosphorylation and Activation of A P34cdc2 Cyclin-B Complex in Vitro by Human Cdc25 Protein. Nature 351:242-245
-
-
Strausfeld, U.1
-
85
-
-
0023790164
-
U.; Peng, Z
-
1988.
-
Sevin, B. U.; Peng, Z. L.; Perras, J. P.; Ganjei, P.; Penalver, M.; Averette, H. E. Application of an ATP-bioluminescence assay in human tumor chemosensitivity testing. Gynecol. Oncol. 31:191-204; 1988.
-
L.; Perras, J. P.; Ganjei, P.; Penalver, M.; Averette, H. E. Application of An ATP-bioluminescence Assay in Human Tumor Chemosensitivity Testing. Gynecol. Oncol. 31:191-204
-
-
Sevin, B.1
-
87
-
-
0031036984
-
Juan, G.; Li, X.; Gorczyca, W.; Murakami, T.; Traganos, F
-
1997.
-
Darzynkiewicz, Z.; Juan, G.; Li, X.; Gorczyca, W.; Murakami, T.; Traganos, F. Cytometry in cell necrobiology-analysis of apoptosis and accidental cell death (necrosis). Cytometry 27:1-20; 1997.
-
Cytometry in Cell Necrobiology-analysis of Apoptosis and Accidental Cell Death (Necrosis). Cytometry 27:1-20
-
-
Darzynkiewicz, Z.1
-
88
-
-
0026565780
-
W.; Camacho, e
-
1992.
-
Wilbur, D. W.; Camacho, E. S.; Milliard, D. A.; Dill, P. L.; Weisenthal, L. M. Chemotherapy of non-small cell lung carcinoma guided by an in vitro drug resistance assay measuring total tumour cell kill. Br. J. Cancer 65:27-32; 1992.
-
S.; Milliard, D. A.; Dill, P. L.; Weisenthal, L. M. Chemotherapy of Non-small Cell Lung Carcinoma Guided by An in Vitro Drug Resistance Assay Measuring Total Tumour Cell Kill. Br. J. Cancer 65:27-32
-
-
Wilbur, D.1
-
90
-
-
0029671112
-
Krajewski, S.; Miyashita, T.; Krajewska, M.; Rccd, J
-
1996.
-
Kitada, S.; Krajewski, S.; Miyashita, T.; Krajewska, M.; Rccd, J. C. Gamma-radiation induces uprcgulation of bax protein and apoptosis in radiosensitive cells m vivo. Oncogene 12:187-192; 1996.
-
C. Gamma-radiation Induces Uprcgulation of Bax Protein and Apoptosis in Radiosensitive Cells M Vivo. Oncogene 12:187-192
-
-
Kitada, S.1
-
91
-
-
0027989808
-
Reutelingsperger, C
-
1415-1420; 1994.
-
Koopman, G.; Reutelingsperger, C. P.; Kuijten, G. A.; Rechnen, R. M.; Pals, S. T.; van-Ocrs, M. H. Annexin V for flow cytomelric detection of phosphatidylserine expression on B cells undergoing apoptosis. Blood 84:1415-1420; 1994.
-
P.; Kuijten, G. A.; Rechnen, R. M.; Pals, S. T.; Van-Ocrs, M. H. Annexin v for Flow Cytomelric Detection of Phosphatidylserine Expression on B Cells Undergoing Apoptosis. Blood 84
-
-
Koopman, G.1
-
92
-
-
0030067696
-
D.; Cooke, T
-
1996.
-
Stanton, P. D.; Cooke, T. G.; Forster, G.; Smith, D.; Going, J. J. Cell kinetics in vivo of human breast cancer. Br. J. Surg. 83:98-102; 1996.
-
G.; Forster, G.; Smith, D.; Going, J. J. Cell Kinetics in Vivo of Human Breast Cancer. Br. J. Surg. 83:98-102
-
-
Stanton, P.1
-
93
-
-
0027869680
-
S.; Holdaway, K
-
1993.
-
Marshall, E. S.; Holdaway, K. M.; Shaw, J. H. R; Finlay, G. J.; Matthews, J. H. L.; Baguley, B. C. Anticancer drug sensitivity profiles of new and established melanoma cell lines. Oncol. Res. 5:301-309; 1993.
-
M.; Shaw, J. H. R; Finlay, G. J.; Matthews, J. H. L.; Baguley, B. C. Anticancer Drug Sensitivity Profiles of New and Established Melanoma Cell Lines. Oncol. Res. 5:301-309
-
-
Marshall, E.1
-
94
-
-
0027447244
-
J.; Marshall, e
-
1993.
-
Finlay, G. J.; Marshall, E. S.; Matthews, J. H. L.; Paull, K. D.; Baguley, B. C. In vitro assessment of N-(2-(dimcthylamino)ethyl)acridine-4-carboxamide, a DNA-intercalating antitumour drug with reduced sensitivity to multidrug resistance. Cancer Chemothcr. Pharmacol. 31:401-406; 1993.
-
S.; Matthews, J. H. L.; Paull, K. D.; Baguley, B. C. in Vitro Assessment of N-(2-(dimcthylamino)ethyl)acridine-4-carboxamide, A DNA-intercalating Antitumour Drug with Reduced Sensitivity to Multidrug Resistance. Cancer Chemothcr. Pharmacol. 31:401-406
-
-
Finlay, G.1
|