Inhibition of cAMP accumulation via recombinant human serotonin 5-HT(1A) receptors: Considerations on receptor effector coupling across systems

Neuropharmacology

Volumn 36, Issue 4-5, 1997, Pages 429-437

  Schoeffter, P ^a   Bobirnac, I ^a   Boddeke, E ^a   Hoyer, D ^a  

^a NOVARTIS PHARMA AG   (Switzerland)

Author keywords

5 HT(1A) receptor; Calcium mobilization; cAMP; Recombinant human 5 HT(1A) receptor

Indexed keywords

1 (2 METHOXYPHENYL) 4 (4 PHTHALIMIDOBUTYL)PIPERAZINE; 2 DIPROPYLAMINO 8 HYDROXYTETRALIN; 4 [4 [4 (1,1,3 TRIOXO 2H 1,2 BENZISOTHIAZOL 2 YL)BUTYL] 1 PIPERAZINYL] 1H INDOLE 2 CARBOXYLIC ACID METHYL ESTER; 8 [2 [(2,3 DIHYDRO 1,4 BENZODIOXIN 2 YL)METHYLAMINO]ETHYL] 8 AZASPIRO[4.5]DECANE 7,9 DIONE; BUSPIRONE; CYCLIC AMP; FORSKOLIN; N [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] N (2 PYRIDYL)CYCLOHEXANECARBOXAMIDE; N TERT BUTYL 3 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL] 2 PHENYLPROPIONAMIDE; PARTIAL AGONIST; PINDOLOL; PROPRANOLOL; SEROTONIN; SEROTONIN 1A AGONIST; SEROTONIN 1A ANTAGONIST; SEROTONIN 1A RECEPTOR;

AGONIST; ARTICLE; BRAIN MEMBRANE; CALCIUM MOBILIZATION; CATTLE; CELL LINE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG ANTAGONISM; DRUG POTENCY; GENE EXPRESSION; GENETIC TRANSFECTION; HELA CELL; HIPPOCAMPUS; HUMAN; HUMAN CELL; MODEL; PRIORITY JOURNAL; RECEPTOR DENSITY; RECEPTOR INTRINSIC ACTIVITY; RECOMBINANT DNA TECHNOLOGY; SECOND MESSENGER; SIGNAL TRANSDUCTION;

ADENYLATE CYCLASE; ANIMALS; CALCIUM; CATTLE; CELL LINE; CYCLIC AMP; FORSKOLIN; HELA CELLS; HIPPOCAMPUS; HUMANS; MEMBRANES; RADIOLIGAND ASSAY; RECEPTORS, SEROTONIN; RECOMBINANT PROTEINS; SEROTONIN AGONISTS; SEROTONIN ANTAGONISTS;

EID: 0030987865     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0028-3908(97)00043-9     Document Type: Article

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