Time resolved kinetics of direct G(β1γ2) interactions with the carboxyl terminus of Kir3.4 inward rectifier K+ channel subunits

Neuropharmacology

Volumn 35, Issue 7, 1996, Pages 923-931

  Doupnik, C A ^a   Dessauer, C W ^b   Slepak, V Z ^b   Gilman, A G ^b   Davidson, N ^a   Lester, H A ^a  

^a CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

^b NONE

Author keywords

G proteins; GST fusion proteins; Inwardly rectifying K channels; Protein protein interactions; Surface plasmon resonance

Indexed keywords

GLUTATHIONE TRANSFERASE; GUANINE NUCLEOTIDE BINDING PROTEIN; POTASSIUM CHANNEL;

ANIMAL CELL; ARTICLE; CHANNEL GATING; CONFORMATION; DISSOCIATION; KINETICS; NONHUMAN; OOCYTE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; XENOPUS;

EID: 0345017560     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/0028-3908(96)00125-6     Document Type: Article

References (37)

1. Clapham D.E. Direct G protein-activation of ion channels? A. Rev. Neurosci. 17:1994;441-464.
2. Dascal N., Doupnik C.A., Ivanina T., Bausch S., Wang W., Lin C., Garvey J., Chavkin C., Lester H.A. and Davidson N. (1995) Inhibition of function in Xenopus oocytes of the inwardly rectifying G protein-activated atrial K channel (GIRK1) by overexpression of a membrane-attached form of the C-terminal tail. Proc. Natl Acad. Sci. U.S.A. 92: 6758-6762.
3. Doupnik C.A., Davidson N., Lester H.A. The inward rectifier potassium channel family. Curr. Opin. Neurobiol. 5:1995;268-277.
4. + channel. J. Gen. Physiol. 106:1995;1-23.
5. + channel activity of neuronal and cardiac G protein-activated inward rectifiers. Biochem. Biophys. Res. Commun. 212:1995;657-663.
6. Fagerstam L.G., Frostell-Karlsson A., Karlsson R., Persson B., Ronnberg I. Biospecific interaction analysis using surface plasmon resonance detection applied to kinetic, binding site and concentration analysis. J. Chromatography. 597:1992;397-410.
7. + channel subunits which interact to form G protein-activated channels. J. Biol. Chem. 270:1995;26086-26091.
8. + channels. Proc. R. Soc. Lond. B 261:1995;251-261.
9. Hille B. G protein-coupled mechanisms and nervous signaling. Neuron. 9:1992;187-195.
10. Hille B. (1992b). Ionic Channels of Excitable Membranes. Sinauer Associates Inc., Sunderland.
11. + channel is important for channel activation. Neuron. 15:1995;1133-1143.
12. + channel, GIRK1. Biochem. Biophys. Res. Commun. 212:1995;1022-1028.
13. Iniguez-Lluhi J.A., Simon M.I., Robishaw J.D., Gilman A.G. G protein βγ subunits sythesized in Sf9 cells. J. Biol. Chem. 267:1992;23409-23417.
14. Jonsson U., Fagerstam L., Ivarsson B., Johnsson B., Karlsson R., Lundh K., Lofas S., Persson B., Roos H., Ronnberg I., Sjolander S., Stenberg E., Stahlberg R., Urbaniczky C., Ostlin H., Malmqvist M. Real-time biospecific interaction analysis using surface plasmon resonance and a sensor chip technology. BioTechniques. 11:1991;620-627.
15. + channels in heart. Proc. Natl Acad. Sci. U.S.A. 88:1991;5694-5698.
16. + channel mRNAs are differentially expressed in the adult rat brain. J. Neurosci. 16:1996;3559-3570.
17. + channel (mGIRK1) and distinct distributions of the three GIRK (GIRK1, 2, and 3) mRNAs in mouse brain. Biochem. Biophys. Res. Commun. 208:1995;1166-1173.
18. + channels are activated by Gβγ subunits and function as heteromultimers. Proc. Natl Acad. Sci. U.S.A. 92:1995;6542-6546.
19. Kozasa T., Gilman A.G. Purification of recombinant G proteins from Sf9 cells by hexahistidine tagging of associated subunits. J. Biol. Chem. 270:1995;1734-1741.
20. +-channel proteins. Nature. 374:1995;135-141.
21. KACh. J. Biol. Chem. 270:1995;29059-29062.
22. Kunkel M.T., Peralta E.G. Identification of domains conferring G protein regulation on inward rectifier potassium channels. Cell. 83:1995;443-449.
23. Lambright D.G., Sondek L., Bohm A., Skiba N.P., Hamm H.E., Sigler P.B. The 2.0 angstrom crystal structure of a heterotrimeric G protein. Nature. 379:1996;311-319.
24. + channels. J. Biol. Chem. 270:1995;28660-28667.
25. Musacchio A., Gibson T., Rice P., Thompson J., Saraste M. The PH domain: a common piece in the structural patchwork of signalling proteins. TIBS. 18:1993;343-348.
26. O'Shannessy D.J., Brigham-Burke M., Soneson K.K., Hensley P., Brooks I. Determination of rate and equilibrium binding constants for macromolecular interactions using surface plasmon resonance: use of nonlinear least squares analysis methods. Anal. Biochem. 212:1993;457-468.
27. Raghavan M., Bjorkman P.J. BIAcore: a microchip-based based system for analysing the formation of macromolecular complexes. Structure. 3:1995;331-333.
28. Reuveny E., Slesinger P.A., Inglese J., Morales J.M., Iniguez-Lluhl J.A., Lefkowitz R.L., Bourne H.R., Jan Y.N., Jan L.Y. Activation of the cloned muscarinic potassium channel by G protein βγ subunits. Nature. 370:1994;143-146.
29. Slepak V.Z., Artemyev N.O., Zhu Y., Dunike C.L., Sabacan L., Sondek J., Hamm H.E., Bownds M.D., Arshavsky V.Y. An effector site that stimulates G protein GTPase in photoreceptors. J. Biol. Chem. 270:1995;14319-14324.
30. Smith D.B. Purification of glutathione S-transferase fusion proteins. Meth. Mol. Cell. Biol. 4:1993;220-229.
31. + channel (GIRK4) from human hippocampus associates with other GIRK channels. J. Neurosci. 16:1996;930-938.
32. Touhara K., Inglese J., Pitcher J., Shaw G., Lefkowitz R.J. Binding of G protein βγ-subunits to pleckstrin homology domains. J. Biol. Chem. 269:1994;10217-10220.
33. Tsukada S., Simon M.I., Witte O.N., Katz A. Binding of βγ subunits of heterotrimeric G proteins to the PH domain of Bruton tyrosine kinase. Proc. Natl Acad. Sci. U.S.A. 91:1994;11256-11260.
34. + channel. FEBS Lett. 379:1996;31-37.
35. iα1β1γ2. Cell. 83:1995;1047-1058.
36. Xu J., Wu D., Slepak V.Z., Simon M.T. The N terminus of phosducin is involved in binding of βγ-subunits of G protein. Proc. Natl Acad. Sci. U.S.A. 92:1995;2086-2090.
37. Yang J., Jan Y.N. and Jan L.Y. (1995) Determination of the subunit stoichiometry of an inwardly rectifying potassium channel. Neuron 15: