Electrophysiological, biochemical, neurohormonal and behavioural studies with WAY-100635, a potent, selective and silent 5-HT1A receptor antagonist

Behavioural Brain Research

Volumn 73, Issue 1-2, 1995, Pages 337-353

  Fletcher, Allan ^a   Forster, Elaine A ^a   Bill, David J ^a   Brown, Geraldine ^a   Cliffe, Ian A ^a   Hartley, Jane E ^a   Jones, Deborah E ^a   McLenachan, Anne ^a   Stanhope, Kelly J ^a   Critchley, David J P ^a   Childs, Kirstie J ^a   Middlefell, Vicki C ^a   Lanfumey, Laurence ^b   Corradetti, Renato ^b   Laporte, Anne Marie ^b   Gozlan, Henri ^b   Hamon, Michel ^b   Dourish, Colin T ^a  

^a PFIZER INC   (United States)

^b PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

Author keywords

5 HT1A receptor; ACTH; Anxiety; Behaviour; Binding; Cognition; Radioligand; Silent antagonist; WAY 100635

Indexed keywords

2 DIPROPYLAMINO 8 HYDROXYTETRALIN; CORTICOTROPIN; N [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] N (2 PYRIDYL)CYCLOHEXANECARBOXAMIDE; N TERT BUTYL 3 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL] 2 PHENYLPROPIONAMIDE; SEROTONIN 1A RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANXIETY; COGNITION; CONFERENCE PAPER; CONTROLLED STUDY; FEMALE; INTRAVENOUS DRUG ADMINISTRATION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RAT; SUBCUTANEOUS DRUG ADMINISTRATION;

ADRENOCORTICOTROPIC HORMONE; ANIMALS; BEHAVIOR, ANIMAL; BRAIN CHEMISTRY; COGNITION; ELECTROPHYSIOLOGY; FEMALE; HIPPOCAMPUS; HYPERPHAGIA; HYPOTHERMIA, INDUCED; MALE; MICE; NEUROTRANSMITTER AGENTS; PIPERAZINES; PYRAMIDAL CELLS; PYRIDINES; RAPHE NUCLEI; RATS; RATS, SPRAGUE-DAWLEY; SEROTONIN ANTAGONISTS;

EID: 0030070276     PISSN: 01664328     EISSN: None     Source Type: Journal    
DOI: 10.1016/0166-4328(96)00118-0     Document Type: Article

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