Central nervous system delivery of interleukin 4 by a nonreplicative herpes simplex type 1 viral vector ameliorates autoimmune demyelination

Human Gene Therapy

Volumn 9, Issue 17, 1998, Pages 2605-2617

  Furlan, R ^a   Poliani, P L ^a   Galbiati, F ^b   Bergami, A ^a   Grimaldi, L M E ^a   Comi, G ^a   Adorini, L ^b   Martino, G ^a  

^a SAN RAFFAELE HOSPITAL   (Italy)

^b ROCHE MILANO RICERCHE   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 4; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; VIRUS VECTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOIMMUNE DISEASE; BRAIN VENTRICLE; CENTRAL NERVOUS SYSTEM; CEREBROSPINAL FLUID; CISTERNA MAGNA; CONTROLLED STUDY; CYTOKINE PRODUCTION; DEMYELINATION; EPENDYMA CELL; GENE TARGETING; GENETIC ENGINEERING; HERPES SIMPLEX VIRUS 1; MOUSE; MULTIPLE SCLEROSIS; NONHUMAN; PARENCHYMA; SUBARACHNOID SPACE; T LYMPHOCYTE;

ANIMALS; CELL DIVISION; CENTRAL NERVOUS SYSTEM; DEFECTIVE VIRUSES; DEMYELINATING DISEASES; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; FEMALE; GENETIC VECTORS; HERPESVIRUS 1, HUMAN; IMMUNOHISTOCHEMISTRY; INTERFERON TYPE II; INTERLEUKIN-4; MICE; MICE, INBRED BALB C; T-LYMPHOCYTES;

ANIMALIA; DNA VIRUSES; HERPES; HUMAN HERPESVIRUS 1;

EID: 0032553682     PISSN: 10430342     EISSN: None     Source Type: Journal    
DOI: 10.1089/10430349850019445     Document Type: Article

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