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A control experiment was performed to determine if a portion of the dihydropyridone product is removed by 1. Dihydropyridone 9 was shaken with 3.4 equivalents of poly-amine resin 1 in a one to one mixture of dichloromethane and acetonitrile for four hours. A 99% yield of 9 was recovered after filtration and concentration
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18. A control experiment was performed to determine if a portion of the dihydropyridone product is removed by 1. Dihydropyridone 9 was shaken with 3.4 equivalents of poly-amine resin 1 in a one to one mixture of dichloromethane and acetonitrile for four hours. A 99% yield of 9 was recovered after filtration and concentration.
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For this small scale array a large excess of polymer-suported amine and morpholine resins were used out of convenience of measuring the resin, but it is not normally necessary to use a large excess
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23. For this small scale array a large excess of polymer-suported amine and morpholine resins were used out of convenience of measuring the resin, but it is not normally necessary to use a large excess.
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