메뉴 건너뛰기




Volumn 9, Issue 4, 1998, Pages 275-289

Physiological, pathophysiological and therapeutic roles of 5-HT systems in learning and memory

Author keywords

5 HT receptors; Learning; Memory; Serotonin

Indexed keywords

SEROTONIN 1A AGONIST; SEROTONIN 2 ANTAGONIST; SEROTONIN 3 ANTAGONIST; SEROTONIN 4 AGONIST; SEROTONIN RECEPTOR;

EID: 0032416852     PISSN: 03341763     EISSN: None     Source Type: Journal    
DOI: 10.1515/REVNEURO.1998.9.4.275     Document Type: Review
Times cited : (84)

References (89)
  • 2
    • 0024158068 scopus 로고
    • What is the nature of the role of the serotonergic nervous system in learning and memory? Prospects for development of an effective treatment strategy for senile dementia
    • Altman HJ, Normile HJ. What is the nature of the role of the serotonergic nervous system in learning and memory? Prospects for development of an effective treatment strategy for senile dementia. Neurobiol Aging 1988; 9: 627-638.
    • (1988) Neurobiol Aging , vol.9 , pp. 627-638
    • Altman, H.J.1    Normile, H.J.2
  • 3
    • 0004602869 scopus 로고    scopus 로고
    • Monoamines and acetylcholine influences on higher cognitive functions in nonhuman primates: Relevance of the treatment of Alzheimer's disease
    • Brioni JD, Decker MW, eds. New York: Wiley-Liss
    • Arnsten AFT, van Dyck CH. Monoamines and acetylcholine influences on higher cognitive functions in nonhuman primates: relevance of the treatment of Alzheimer's disease. In: Brioni JD, Decker MW, eds. Neuropathology and Functional Anatomy of Alzheimer's Disease. Pharmacological Treatment of Alzheimer's Disease. New York: Wiley-Liss, 1997; 63-86.
    • (1997) Neuropathology and Functional Anatomy of Alzheimer's Disease. Pharmacological Treatment of Alzheimer's Disease , pp. 63-86
    • Arnsten, A.F.T.1    Van Dyck, C.H.2
  • 4
    • 0002048563 scopus 로고    scopus 로고
    • Development and adult plasticity of serotoninergic neurons and their target cells
    • Baumgarten HG, Gother M, eds. Berlin: Springer-Verlag
    • Azmitia EC, Whitaker-Azmitia P. Development and adult plasticity of serotoninergic neurons and their target cells. In: Baumgarten HG, Gother M, eds. Serotoninergic Neurons and 5-HT Receptors in the CNS. Berlin: Springer-Verlag, 1997; 1-39.
    • (1997) Serotoninergic Neurons and 5-HT Receptors in the CNS , pp. 1-39
    • Azmitia, E.C.1    Whitaker-Azmitia, P.2
  • 5
    • 0041999544 scopus 로고    scopus 로고
    • Attenuated MK-801 -induced impairment of radial maze performance in rats. A possible model predicting efficacy in Alzheimer's disease
    • Bartolomeo AC, Morris H, Moyer JA, Boast CA. Attenuated MK-801 -induced impairment of radial maze performance in rats. A possible model predicting efficacy in Alzheimer's disease. Soc Neurosci Abst 1996; 22: 143.
    • (1996) Soc Neurosci Abst , vol.22 , pp. 143
    • Bartolomeo, A.C.1    Morris, H.2    Moyer, J.A.3    Boast, C.A.4
  • 7
    • 0031004070 scopus 로고    scopus 로고
    • Serotonin receptors in cognitive behaviors
    • Buhot MC. Serotonin receptors in cognitive behaviors. Curr Opin Neurobiol 1997; 7: 243-254.
    • (1997) Curr Opin Neurobiol , vol.7 , pp. 243-254
    • Buhot, M.C.1
  • 8
    • 0026543763 scopus 로고
    • 8-Hydroxy-2-(di-n-propylamino) tetralin impairs spatial learning in a water maze: Role of postsynaptic 5-HT1A
    • Carli M, Samanin R. 8-Hydroxy-2-(di-n-propylamino) tetralin impairs spatial learning in a water maze: role of postsynaptic 5-HT1A. Br J Pharmacol 1992; 105: 720-726.
    • (1992) Br J Pharmacol , vol.105 , pp. 720-726
    • Carli, M.1    Samanin, R.2
  • 10
    • 0029080364 scopus 로고
    • Serotonergic modulation of cholinergic function in the central nervous system: Cognitive implications
    • Cassel JC, Jeltsch H. Serotonergic modulation of cholinergic function in the central nervous system: cognitive implications. Neuroscience 1995; 69: 1-41.
    • (1995) Neuroscience , vol.69 , pp. 1-41
    • Cassel, J.C.1    Jeltsch, H.2
  • 11
    • 0028172231 scopus 로고
    • 1A receptor agonists improve the performance of normal and scopolamine-impaired rats in an operant delayed matching to position task
    • 1A receptor agonists improve the performance of normal and scopolamine-impaired rats in an operant delayed matching to position task. Psychopharmacology 1994; 116: 135-142.
    • (1994) Psychopharmacology , vol.116 , pp. 135-142
    • Cole, B.J.1    Jones, G.H.2    Turner, J.D.3
  • 15
    • 0001353661 scopus 로고
    • Strategies for testing learning and memory abilities in transplanted rats
    • Dunnett SD, Björklund A, eds. New York: Raven Press
    • Dunnett SB. Strategies for testing learning and memory abilities in transplanted rats. In: Dunnett SD, Björklund A, eds. Functional Neural Transplantation. New York: Raven Press, 1994; 217-251.
    • (1994) Functional Neural Transplantation , pp. 217-251
    • Dunnett, S.B.1
  • 26
    • 0002721710 scopus 로고
    • 5-HT receptors and cognitive function
    • Marsden CA, Heal DJ, eds. Oxford: Blackwell Scientific Publications
    • Gower AJ. 5-HT receptors and cognitive function. In: Marsden CA, Heal DJ, eds. Central serotonin receptors and psychotropic drugs. Oxford: Blackwell Scientific Publications, 1992; 239-259.
    • (1992) Central Serotonin Receptors and Psychotropic Drugs , pp. 239-259
    • Gower, A.J.1
  • 27
    • 0001252167 scopus 로고    scopus 로고
    • Regulation of 5-HT release in the CNS by presynaptic 5-HT autoreceptors and by 5-HT heteroreceptors
    • Baumgarten HG, Gother M, eds. Berlin: Springer-Verlag
    • Göthert M, Schlicker E. Regulation of 5-HT release in the CNS by presynaptic 5-HT autoreceptors and by 5-HT heteroreceptors. In: Baumgarten HG, Gother M, eds. Serotoninergic Neurons and 5-HT Receptors in the CNS. Berlin: Springer-Verlag, 1997; 307-350.
    • (1997) Serotoninergic Neurons and 5-HT Receptors in the CNS , pp. 307-350
    • Göthert, M.1    Schlicker, E.2
  • 28
    • 0030250008 scopus 로고    scopus 로고
    • Combined PCPA and muscarinic antagonist treatment produces a deficit in rat water maze acquisition
    • Harder JA, Kelley ME, Cheng CHK, Costall B. Combined PCPA and muscarinic antagonist treatment produces a deficit in rat water maze acquisition. Pharmacol Biochem Behav 1996; 55: 61-65.
    • (1996) Pharmacol Biochem Behav , vol.55 , pp. 61-65
    • Harder, J.A.1    Kelley, M.E.2    Cheng, C.H.K.3    Costall, B.4
  • 30
    • 13344269036 scopus 로고    scopus 로고
    • Serotonergic regulation of associate learning
    • Harvey JA. Serotonergic regulation of associate learning. Behav Brain Res 1996; 73: 47-50.
    • (1996) Behav Brain Res , vol.73 , pp. 47-50
    • Harvey, J.A.1
  • 31
    • 0030011343 scopus 로고    scopus 로고
    • 3 antagonists WAY-100579 and ondansetron on spatial learning in the water maze in rats with excitotoxic lesions of the forebrain cholinergic projection system
    • 3 antagonists WAY-100579 and ondansetron on spatial learning in the water maze in rats with excitotoxic lesions of the forebrain cholinergic projection system. Psychopharmacology 1996; 125: 146-161.
    • (1996) Psychopharmacology , vol.125 , pp. 146-161
    • Hodges, H.1    Sowinski, P.2    Turner, J.J.3    Fletcher, A.4
  • 34
    • 0028183017 scopus 로고
    • International Union of Pharmacology classification of receptors for 5-hydroxytryptamine (serotonin)
    • Hoyer D, Hartig PR, Humphrey PPA. International Union of Pharmacology classification of receptors for 5-hydroxytryptamine (serotonin). Pharmacol Rev 1994; 46: 157-203.
    • (1994) Pharmacol Rev , vol.46 , pp. 157-203
    • Hoyer, D.1    Hartig, P.R.2    Humphrey, P.P.A.3
  • 35
    • 13344280365 scopus 로고    scopus 로고
    • Classification and nomenclature of 5-HT receptors: A comment on current issues
    • Hoyer D, Martin GR. Classification and nomenclature of 5-HT receptors: a comment on current issues. Behav Brain Res 1996; 73: 263-268.
    • (1996) Behav Brain Res , vol.73 , pp. 263-268
    • Hoyer, D.1    Martin, G.R.2
  • 36
    • 0026515597 scopus 로고
    • Structure and function of the brain serotonin system
    • Jacobs BL, Azmitia EC. Structure and function of the brain serotonin system. Physiol Rev 1992; 72: 165-229.
    • (1992) Physiol Rev , vol.72 , pp. 165-229
    • Jacobs, B.L.1    Azmitia, E.C.2
  • 40
    • 0001557644 scopus 로고
    • 1C receptors and their therapeutic relevance
    • 1C receptors and their therapeutic relevance. Curr Opin Invest Drugs 1993; 2: 317-362.
    • (1993) Curr Opin Invest Drugs , vol.2 , pp. 317-362
    • Kennett, G.A.1
  • 42
    • 0029657985 scopus 로고    scopus 로고
    • 1A receptors are expressed by a subpopulation of cholinergic neurons in the rat medial septum and diagonal band of Broca - A double immunocytochemical study
    • 1A receptors are expressed by a subpopulation of cholinergic neurons in the rat medial septum and diagonal band of Broca - a double immunocytochemical study. Neuroscience 1996; 74: 143-154.
    • (1996) Neuroscience , vol.74 , pp. 143-154
    • Kia, H.K.1    Brisorgueil, M.J.2    Daval3    Langlois, X.4    Hamon, M.5    Vergé, D.6
  • 46
    • 0031881937 scopus 로고    scopus 로고
    • The structure and signaling properties of 5-HT receptors: And endless diversity?
    • Martin GR, Eglen RM, Hamblin MW, Hoyer D, Yocca F. The structure and signaling properties of 5-HT receptors: and endless diversity? TIPS 1998; 19: 2-4.
    • (1998) TIPS , vol.19 , pp. 2-4
    • Martin, G.R.1    Eglen, R.M.2    Hamblin, M.W.3    Hoyer, D.4    Yocca, F.5
  • 47
    • 0030744239 scopus 로고    scopus 로고
    • Serotonin depletion during synaptogenesis leads to decreased synaptic density and learning deficits in the adult brain: A possible model of neurodevelopmental disorders with cognitive deficits
    • Mazer C, Muneyyirci J, Taheny K, Raio N, Borella A, Whitaker-Azmitia P. Serotonin depletion during synaptogenesis leads to decreased synaptic density and learning deficits in the adult brain: a possible model of neurodevelopmental disorders with cognitive deficits. Brain Res 1997; 760: 68-73.
    • (1997) Brain Res , vol.760 , pp. 68-73
    • Mazer, C.1    Muneyyirci, J.2    Taheny, K.3    Raio, N.4    Borella, A.5    Whitaker-Azmitia, P.6
  • 49
    • 0000476905 scopus 로고    scopus 로고
    • 5-HT receptors as targets for drugs in the treatment of learning and memory dysfunctions
    • Meneses A. 5-HT receptors as targets for drugs in the treatment of learning and memory dysfunctions. Curr Res Serotonin 1998; 3: 219-228.
    • (1998) Curr Res Serotonin , vol.3 , pp. 219-228
    • Meneses, A.1
  • 50
    • 2442737593 scopus 로고    scopus 로고
    • 2A/2B/2C receptors involved in learning and memory processes?
    • in press
    • 2A/2B/2C receptors involved in learning and memory processes? Curr Res Serotonin 1999; in press.
    • (1999) Curr Res Serotonin
    • Meneses, A.1
  • 51
    • 0029121238 scopus 로고
    • Effect of fluoxetine on learning and memory involve multiple 5-HT systems
    • Meneses A, Hong E. Effect of fluoxetine on learning and memory involve multiple 5-HT systems. Pharmacol Biochem Behav 1995; 52: 341-346.
    • (1995) Pharmacol Biochem Behav , vol.52 , pp. 341-346
    • Meneses, A.1    Hong, E.2
  • 52
    • 0030614807 scopus 로고    scopus 로고
    • 4 receptor agonists and antagonists in learning
    • 4 receptor agonists and antagonists in learning. Pharmacol Biochem Behav 1997; 56: 347-351.
    • (1997) Pharmacol Biochem Behav , vol.56 , pp. 347-351
    • Meneses, A.1    Hong, E.2
  • 53
    • 0030980481 scopus 로고    scopus 로고
    • A pharmacological analysis of serotonergic receptors: Effects of their activation or blockade in learning
    • Meneses A, Hong E. A pharmacological analysis of serotonergic receptors: effects of their activation or blockade in learning. Prog Neuro-Psychopharmacol Biol Psychiat 1997; 21: 273-296.
    • (1997) Prog Neuro-Psychopharmacol Biol Psychiat , vol.21 , pp. 273-296
    • Meneses, A.1    Hong, E.2
  • 54
    • 0030920341 scopus 로고    scopus 로고
    • 1A receptors in acquisition, consolidation and retrieval of learning
    • 1A receptors in acquisition, consolidation and retrieval of learning. CNS Drug Rev 1997; 3: 68-82.
    • (1997) CNS Drug Rev , vol.3 , pp. 68-82
    • Meneses, A.1    Hong, E.2
  • 56
    • 0031954591 scopus 로고    scopus 로고
    • Spontaneous hypertensive rat: A potential model to identify drugs for treatment of learning disorders
    • Meneses A, Hong E. Spontaneous hypertensive rat: a potential model to identify drugs for treatment of learning disorders. Hypertension 1998; 31: 968-972.
    • (1998) Hypertension , vol.31 , pp. 968-972
    • Meneses, A.1    Hong, E.2
  • 57
    • 0032588309 scopus 로고    scopus 로고
    • 1A receptors modulate the consolidation of learning in normal and cognitively impaired rats
    • in press
    • 1A receptors modulate the consolidation of learning in normal and cognitively impaired rats. Neurobiol Learning Memory 1999; in press.
    • (1999) Neurobiol Learning Memory
    • Meneses, A.1    Hong, E.2
  • 62
    • 0026032356 scopus 로고
    • Involvement of central cholinergic mechanism in RU-24969-induced behavioral deficits
    • Noda Y, Ochi Y, Shimada E, Oka M. Involvement of central cholinergic mechanism in RU-24969-induced behavioral deficits. Pharmacol Biochem Behav 1991; 38: 441-446.
    • (1991) Pharmacol Biochem Behav , vol.38 , pp. 441-446
    • Noda, Y.1    Ochi, Y.2    Shimada, E.3    Oka, M.4
  • 64
    • 0031148396 scopus 로고    scopus 로고
    • Chicks injected with antisera to either S-100α or S-100β protein develop amnesia for a passive avoidance task
    • O'Dowd BS, Zhao WQ, Ng KT, Robinson SR. Chicks injected with antisera to either S-100α or S-100β protein develop amnesia for a passive avoidance task. Neurobiol Learning Memory 1997; 67: 197-206.
    • (1997) Neurobiol Learning Memory , vol.67 , pp. 197-206
    • O'Dowd, B.S.1    Zhao, W.Q.2    Ng, K.T.3    Robinson, S.R.4
  • 65
    • 0030038264 scopus 로고    scopus 로고
    • 3 receptor antagonist, in the treatment of central nervous system disorders
    • 3 receptor antagonist, in the treatment of central nervous system disorders. CNS Drug Rev 1996; 2: 195-213.
    • (1996) CNS Drug Rev , vol.2 , pp. 195-213
    • Passani, M.B.1    Corradetti, R.2
  • 66
    • 0030880031 scopus 로고    scopus 로고
    • 1B/1D receptor antagonists
    • 1B/1D receptor antagonists. Gen Pharmac 1997; 29: 293-303.
    • (1997) Gen Pharmac , vol.29 , pp. 293-303
    • Pauwels, P.1
  • 71
    • 0029415354 scopus 로고
    • 1A receptor agonist and muscarinic acetylcholine receptor antagonist disrupts water maze navigation behavior
    • 1A receptor agonist and muscarinic acetylcholine receptor antagonist disrupts water maze navigation behavior. Psychopharmacology 1995; 122: 137-146.
    • (1995) Psychopharmacology , vol.122 , pp. 137-146
    • Riekkinen, M.1    Sirvio, J.2    Toivanen, T.3    Riekkinen, P.4
  • 73
    • 0345196000 scopus 로고    scopus 로고
    • The role of the dorsal raphe-serotonergic system and cholinergic receptors in the modulation of working memory
    • Ruotsalainen S, Miettinen R, Macdonald E, Riekkinen M, Sirvio J. The role of the dorsal raphe-serotonergic system and cholinergic receptors in the modulation of working memory. Neurosci Biobehav Rev 1998; 22: 21-31.
    • (1998) Neurosci Biobehav Rev , vol.22 , pp. 21-31
    • Ruotsalainen, S.1    Miettinen, R.2    Macdonald, E.3    Riekkinen, M.4    Sirvio, J.5
  • 74
    • 0344770107 scopus 로고
    • Impairment of spatial learning induced by intrahippocampal scopolamine: Its reversal by arecoline, ondansetron and intrahippocampal (+)-WAY 100135
    • Samanin R, Luschi R, Vezzani A, Carli M. Impairment of spatial learning induced by intrahippocampal scopolamine: its reversal by arecoline, ondansetron and intrahippocampal (+)-WAY 100135. Soc Neurosci Abstr 1994; 20: 149.
    • (1994) Soc Neurosci Abstr , vol.20 , pp. 149
    • Samanin, R.1    Luschi, R.2    Vezzani, A.3    Carli, M.4
  • 75
    • 0030051587 scopus 로고    scopus 로고
    • Excessive serotonin release, not depletion, leads to memory impairments in rats
    • Santucci AC, Knott PJ, Haroutunian V. Excessive serotonin release, not depletion, leads to memory impairments in rats. Eur J Pharmacol 1996; 295: 7-17.
    • (1996) Eur J Pharmacol , vol.295 , pp. 7-17
    • Santucci, A.C.1    Knott, P.J.2    Haroutunian, V.3
  • 79
    • 0000982288 scopus 로고    scopus 로고
    • Neuropathology and functional anatomy of Alzheimer's disease
    • Brioni JD, Decker MW, eds. New York: Wiley-Liss
    • Solodkin A, van Hoesen GW. Neuropathology and functional anatomy of Alzheimer's disease. In: Brioni JD, Decker MW, eds. Pharmacological Treatment of Alzheimer's Disease. New York: Wiley-Liss, 1997; 151-177.
    • (1997) Pharmacological Treatment of Alzheimer's Disease , pp. 151-177
    • Solodkin, A.1    Van Hoesen, G.W.2
  • 80
    • 0028810472 scopus 로고
    • Dissociation between cognitive and motor/motivational deficits in the delayed matching to position test: Effects of scopolamine, 8-OH-DPAT and EAA antagonists
    • Stanhope KJ, McLenachan AP, Dourish CT. Dissociation between cognitive and motor/motivational deficits in the delayed matching to position test: effects of scopolamine, 8-OH-DPAT and EAA antagonists. Psychopharmacology 1995; 122: 268-280.
    • (1995) Psychopharmacology , vol.122 , pp. 268-280
    • Stanhope, K.J.1    McLenachan, A.P.2    Dourish, C.T.3
  • 81
    • 0028955454 scopus 로고
    • 3 receptor antagonism on hippocampal theta rhythm, memory, and LTP induction in the freely moving rat
    • 3 receptor antagonism on hippocampal theta rhythm, memory, and LTP induction in the freely moving rat. J Neurosci 1995; 15: 2445-2452.
    • (1995) J Neurosci , vol.15 , pp. 2445-2452
    • Staubli, U.1    Xu, F.B.2
  • 82
    • 0028924167 scopus 로고
    • The role of serotonergic-cholinergic interactions in the mediation of cognitive behavior
    • Steckler T, Sahgal A. The role of serotonergic-cholinergic interactions in the mediation of cognitive behavior. Behav Brain Res 1995; 67: 165-199.
    • (1995) Behav Brain Res , vol.67 , pp. 165-199
    • Steckler, T.1    Sahgal, A.2
  • 86
    • 0028985633 scopus 로고
    • Comparative localization of serotonin IA, 1C and 2 receptor subtype mRNAs in rat brain
    • Wright, DE., Seroogy, KB., Lundgren, KH., Davis, BM. and Jennes, L. Comparative localization of serotonin IA, 1C and 2 receptor subtype mRNAs in rat brain. J Comp Neurol. 1995; 351: 357-373.
    • (1995) J Comp Neurol. , vol.351 , pp. 357-373
    • Wright, D.E.1    Seroogy, K.B.2    Lundgren, K.H.3    Davis, B.M.4    Jennes, L.5
  • 88
    • 0026761109 scopus 로고
    • 5-Hydroxytryptamine receptors
    • Zifa E, Fillion G. 5-Hydroxytryptamine receptors. Pharmacol Rev 1992; 44: 401-458.
    • (1992) Pharmacol Rev , vol.44 , pp. 401-458
    • Zifa, E.1    Fillion, G.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.