Wortmannin-sensitive trafficking pathways in Chinese hamster ovary cells: Differential effects on endocytosis and lysosomal sorting

Journal of Biological Chemistry

Volumn 271, Issue 18, 1996, Pages 10953-10962

  Martys, Jayme L ^c   Wjasow, Christina ^a   Gangi, Dawn M ^a   Kielian, Margaret C ^b   McGraw, Timothy E ^c   Backer, Jonathan M ^a,b  

^a Department of Molecular Pharmacology ^*  (United States)

^b ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^c College of Physicians and Surgeons ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATHEPSIN D; CELL ENZYME; PHOSPHATIDYLINOSITOL 3 KINASE; TRANSFERRIN RECEPTOR; WORTMANNIN;

ANIMAL CELL; ARTICLE; CHO CELL; ENDOCYTOSIS; ENDOSOME; INTERNALIZATION; INTRACELLULAR KILLING; INTRACELLULAR TRANSPORT; LYSOSOME; NONHUMAN; PRIORITY JOURNAL; RECYCLING; SEMLIKI FOREST ALPHAVIRUS;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANDROSTADIENES; ANIMALS; BIOLOGICAL TRANSPORT; CHO CELLS; CRICETINAE; CRICETULUS; ENDOCYTOSIS; ENZYME INHIBITORS; HYDROGEN-ION CONCENTRATION; LYSOSOMES; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR);

EID: 15844427939     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.271.18.10953     Document Type: Article

References (74)

1. Otsu, M., Hiles, I., Gout, I., Fry, M. J., Ruiz-Larrea, F., Panayotcu, G., Thompson, A., Dhand, R., Hsuan, J., Totty, N., Smith, A. D., Morgan, S. J., Courtneidge, S. A., Parker, P. J., and Waterfield, M. D. (1991) Cell 65, 91-104
2. Hues, I. D., Otsu, M., Volinia, S., Fry, M. J., Gout, I., Dhand, R., Panayotou, G., Ruiz-Larrea, F., Thompson, A., Totty, N. F., Hsuan, J. J., Courtneidge, S. A., Parker, P. J., and Waterfield, M. D. (1992) Cell 70, 419-429
3. Escobedo, J. A., Navankasattusas, S., Kavanaugh, W. M., Milfay, D., Fried, V. A., and Williams, L. T. (1991) Cell 65, 75-82
4. Skolnik, E. Y., Margolis, B., Mohammadi, M., Lowenstein, E., Fischer, R., Drepps, A., Ullrich, A., and Schlessinger, J. (1991) Cell 65, 83-90
5. Hu, P., Mondino, A., Skolnik, E. Y., and Schlessinger, J. (1993) Mol. Cell. Biol. 13, 7677-7688
6. Cantley, L. C., Auger, K. R., Carpenter, C., Duckworth, B., Graziani, A., Kapeller, R., and Soltoff, S. (1991) Cell 64, 281-302
7. Backer, J. M., Myers, M. G., Jr., Shoelson, S. E., Chin, D. J., Sun, X. J., Miralpeix, M., Hu, P., Margolis, B., Skolnik, E. Y., Schlessinger, J., and White, M. F. (1992) EMBO J. 11, 3469-3479
8. Carpenter, C. L., Auger, K. R., Chanudhuri, M., Yoakim, M., Schaflhausen, B., Shoelson, S., and Cantley, L. C. (1993) J. Biol Chem. 268, 9478-9483
9. Pleiman, C. M., Hertz, W. M., and Gambier, J. C. (1994) Science 263, 1609-1612
10. Zhang, J., King, W. G., Dillon, S., Hall, A., Feig, L., and Rittenhouse, S. E. (1993) J. Biol. Chem. 268, 22251-22254
11. Rodriguez-Viciana, P., Warne, P. H., Dhand, R., Vanhaesebroeck, B., Gout, I., Fry, M. J., Waterfield, M. D., and Downward, J. (1994) Nature 370, 527-532
12. Auger, K. R., Serunian, L. A., Soltoff, S. P., Libby, P., and Cantley, L. C. (1989) Cell 57, 167-175
13. Nakanishi, H., Brewer, K. A., and Exton, J. H. (1993) J. Biol. Chem. 268, 13-16
14. Toker, A., Meyer, M., Reddy, K. K., Falck, J. R., Aneja, R., Aneja, S., Parra, A., Burns, D. J., Balks, L. M., and Cantley, L. C. (1994) J. Biol. Chem. 269, 32358-32367
15. Dhand, R., Hiles, I., Panayotou, G., Roche, S., Fry, M. J., Gout, I., Totty, N. F., Truong, O., Vicendo, P., Yonezawa, K., Kasuga, M., Courtneidge, S. A., and Waterfield, M. D. (1994) EMBO J. 13, 522-533
16. Volinia, S., Dhand, R., Vanhaesebroeck, B., MacDougall, L. K., Stein, R., Zvelebil, M. J., Domin, J., Panaretou, C., and Waterfield, M. D. (1995) EMBO J. 14, 3339-3348
17. Stephens, L., Smrckq, A., Cooke, F. T., Jackson, T. R., Sternweis, P. C., and Hawkins, P. T. (1994) Cell 77, 83-93
18. Stoyanov, B., Volinia, S., Hanck, T., Rubio, I., Loubtahenkov, M., Malek, D., Stoyanova, S., Vanhaesebroeck, B., Dhand, R., Nurnberg, B., Gierschik, P., Seedorf, K., Hsuan, J. J., Waterfield, M. D., and Wetzker, R. (1995) Science 269, 690-693
19. Herman, P. K., Stack, J. H., and Emr, S. D. (1992) Trends Cell Biol. 2, 363-368
20. Schu, P. V., Takegawa, K., Fry, M. J., Stack, J. H., Waterfield, M. D., and Emr, S. D. (1993) Science 260, 88-91
21. Stack, J. H., and Emr, S. D. (1994) J. Biol. Chem. 269, 31552-31562
22. Kodaki, T., Woscholski, R., Emr, S., Waterfield, M. D., Nurse, P., and Parker, P. J. (1994) Eur. J. Biochem. 219, 775-780
23. Joly, M., Kazlauskas, A., and Corvera, S. (1995) J. Biol. Chem. 270, 13225-13230
24. Nishimura, R., Li, W., Kashishian, A., Mondino, A., Zhou, M., Cooper, J., and Schlessinger, J. (1993) Mol Cell Biol. 13, 6889-6896
25. Clarke, J. F., Young, P. W., Yonezawa, K., Kasuga, M., and Holman, G. D. (1994) Biochem. J. 300, 631-635
26. Yano, H., Nakanishi, S., Kimura, K., Hanai, N., Saitoh, Y., Fukui, Y., Nonomura, Y., and Matsuda, Y. (1993) J. Biol. Chem. 268, 25846-25856
27. Thelen, M., Wymann, M. P., and Langen, H. (1994) Proc. Natl. Acad. Sci. U. S. A. 91, 4960-4964
28. Arcaro, A., and Wymann, M. P. (1993) Biochem. J. 296, 297-301
29. Cheatham, B., Vlahos, C. J., Cheatham, L., Wang, L., Blenis, J., and Kahn, C. R. (1994) Mol. Cell. Biol. 14, 4902-4911
30. Lee, A. D., Hansen, P. A., and Holbszy, J. O. (1995) FEBS Lett. 361, 51-54
31. Yeh, J.-I., Gulve, E. A., Rameh, L., and Birnbaum, M. J. (1995) J. Biol. Chem. 270, 2107-2111
32. Nakanishi, S., Catt, K. J., and Balla, T. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 5317-5321
33. McGraw, T. E., Pytowski, B., Arzt, J., and Ferrone, C. (1991) J. Cell Biol. 112, 853-861
34. Ullrich, A., Bell, J. R., Chen, E. Y., Herrera, R., Petruzzelli, L. M., Dull, T. J., Gray, A., Coussens, L., Liao, Y.-C., Tsubokawa, M., Mason, A., Seeburg, P. H., Grunfeld, C., Rosen, O. M., and Ramachandran, J. (1985) Nature 313, 756-761
35. White, M. F., Livingston, J. N., Backer, J. M., Lauris, V., Dull, T. J., Ullrich, A., and Kahn, C. R. (1988) Cell 54, 641-649
36. Wiley, H. S., and Cunningham, D. D. (1982) J. Biol. Chem. 257, 4222-4229
37. Backer, J. M., Shoelson, S. E., Haring E., and White, M. F. (1991) J. Cell Biol. 115, 1535-1545
38. Dunn, K. W., McGraw, T. E., and Maxfield, F. R. (1989) J. Cell Biol. 109, 3303-3314
39. Kielian, M. C., and Helenius, A. (1984) J. Virol. 52, 281-283
40. Kielian, M., Jungerwirth, S., Sayad, K. U., and DeCandido, S. (1990) J. Virol. 64, 4614-4624
41. Phalen, T., and Kielian, M. (1991) J. Cell Biol. 112, 615-623
42. Duffus, W. A., Levy-Mintz, P., Klimjack, M. R., and Kielian, M. (1995) J. Virol. 69, 2471-2479
43. Laemmli, U. K. (1970) Nature 227, 680-685
44. Rosenwald, A. G., Machamer, C. E., and Pagano, R. E. (1992) Biochemistry 31, 3581-3590
45. Richo, G. R., and Conner, G. E. (1994) J. Biol. Chem. 269, 14806-14812
46. Watts, C. (1985) J. Cell Biol. 100, 633-637
47. Carpentier, J. L., Paccaud, J. P., Gorden, P., Rutter, W. J., and Orci, L. (1992) Proc. Natl. Acad. Sci. U. S. A. 89, 162-166
48. Goncalves, E., Yamada, K., Thatte, H. S., Backer, J. M., Golan, D. E., Kahn, C. R., and Shoelson, S. E. (1993) Proc. Natl. Acad. Sci. U. S. A. 90, 5762-5766
49. Marsh, M., and Helenius, A. (1989) Adv. Virus Res. 36, 107-151
50. Strous, G. J. A. M., and Lodish, H. F. (1980) Cell 22, 709-717
51. deCurtis, I., and Simons, K. (1988) Proc. Natl. Acad. Sci. U.S.A. 852, 8052-8056
52. Kornfeld, S. (1987) FASEB J. 1, 462-468
53. Dong, J. M., Prence, E. M., and Sahagian, G. G. (1989) J. Biol. Chem. 264, 7377-7383
54. Brown, W. J., DeWald, D. B., Emr, S. D., Plutner, H., and Balch, W. E. (1995) J. Cell Biol. 130, 781-796
55. Davidson, H. W. (1995) J. Cell Biol. 130, 797-805
56. Braulke, T., Geuze, H. J., Slot, J. W., Hasilik, A., and von Figura, K. (1987) Eur. J. Cell Biol. 43, 316-321
57. Nakanishi, S., Kakita, S., Takahashi, I., Kawahara, K., Tsukuda, E., Sano, T., Yamada, K., Yoshida, M., Kase, H., Matsuda, Y., Hashimoto, Y., and Nonomura, Y. (1992) J. Biol. Chem. 267, 2157-2163
58. Powis, G., Bonjouklian, R., Berggren, M. M., Gallegos, A., Abraham, R., Ashendel, C., Zalkow, L., Matter, W. F., Dodge, J., Grindey, G., and Vlahos, C. J. (1994) Cancer Res. 54, 2419-2423
59. Woscholski, R., Kodaki, T., McKinnon, M., Watcrficld, M. D., and Parker, P. J. (1994) FEBS Lett. 342, 109-114
60. Beck, K. A., and Keen, J. H. (1991) J. Biol. Chem. 266, 4442-4447
61. Goldschmidt-Clermont, P. J., Machesky, L. M., Baldessare, J. J., and Pollard, T. D. (1990) Science 247, 1575-1578
62. Hay, J. C., Fisette, P. L., Jenkins, G. H., Fukami, K., Takenawa, T., Anderson, R. A., and Martin, T. F. (1995) Nature 374, 173-177
63. Harlan, J. E., Hajduk, P. J., Yoon, H. S., and Fesik, S. W. (1994) Nature 371, 168-170
64. Presley, J. F., Mayor, S., Dunn, K. W., Johnson, L. S., McGraw, T. E., and Maxfield, F. R. (1993) J. Cell Biol. 122, 1231-1241
65. Johnson, L. S., Dunn, K. W., Pytowski, B., and McGraw, T. E. (1993) Mol. Biol. Cell 4, 1251-1266
66. Li, G., D'Souza-Schorey, C., Barbieri, M. A., Roberts, R. L., Klippel, A., Williams, L. T., and Stahl, P. D. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 10207-10211
67. Marsh, E. W., Leopold, N. L., Jones, N. L., and Maxfield, F. R. (1995) J. Cell Biol. 129, 1509-1522
68. Weigel, P. H. (1992) in Glycoconjugates (Allen, H. J., and Kisailus, E. C., eds) pp. 421-498, Marcel Dekker, Inc., New York
69. Stockert, R. J., Potvin, B., Tao, L., Stanley, P., and Wolkoff, A. W. (1995) J. Biol. Chem. 270, 16107-16113
70. Endemann, G., Yonezawa, K., and Roth, R. A. (1990) J. Biol. Chem. 265, 396-400
71. Ruderman, N., Kapeller, R., White, M. F., and Cantley, L. C. (1990) Proc. Natl. Acad. Sci. U. S. A. 87, 1411-1415
72. Kapeller, R., Chem, K. S., Yoakim, M., Schaflhausen, B. S., Backer, J. M., White, M. F., Cantley, L. C., and Ruderman, N. B. (1991) Mol. Endocrinol. 5, 769-777
73. Backer, J. M., Shoelson, S. E., Weiss, M. A., Hua, Q. X., Cheatham, R. B., Haring, E., Cahill, D. C., and White, M. F. (1992) J. Cell Biol. 118, 831-839
74. Shepherd, P. R., Soos, M. A., and Siddle, K. (1995) Biochem. Biophys. Res. Commun. 211, 535-539