메뉴 건너뛰기




Volumn 109, Issue 4, 1996, Pages 749-762

The effect of wortmannin on the localisation of lysosomal type I integral membrane glycoproteins suggests a role for phosphoinositide 3-kinase activity in regulating membrane traffic late in the endocytic pathway

Author keywords

lgp120; PI 3 kinase; Wortmannin

Indexed keywords

GLYCOPROTEIN; MEMBRANE PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOTRANSFERASE; SOMATOMEDIN B RECEPTOR; WORTMANNIN;

EID: 0029863528     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (154)

References (66)
  • 1
    • 0024999529 scopus 로고
    • Purification and characterization of a major glycoprotein in rat liver lysosomal membrane
    • Akasaki, K., Yamaguchi, Y., Ohta, M., Matsura, F., Furuno, K. and Tsuji, H. (1990). Purification and characterization of a major glycoprotein in rat liver lysosomal membrane Chem. Pharm Bull. 38, 2766-2770.
    • (1990) Chem. Pharm Bull. , vol.38 , pp. 2766-2770
    • Akasaki, K.1    Yamaguchi, Y.2    Ohta, M.3    Matsura, F.4    Furuno, K.5    Tsuji, H.6
  • 2
    • 0029084767 scopus 로고
    • Biosynthetic transport of a major lysosomal membrane glycoprotein, Lamp-1: Convergence of biosynthetic and endocytic pathways occurs at three distinctive points
    • Akasaki, K., Michihara, A., Mibuka, K., Fujiwara, Y. and Tsuji, H. (1995). Biosynthetic transport of a major lysosomal membrane glycoprotein, Lamp-1: convergence of biosynthetic and endocytic pathways occurs at three distinctive points. Exp. Cell Res. 220, 464-473.
    • (1995) Exp. Cell Res. , vol.220 , pp. 464-473
    • Akasaki, K.1    Michihara, A.2    Mibuka, K.3    Fujiwara, Y.4    Tsuji, H.5
  • 3
    • 0021800788 scopus 로고
    • Characterization of protein transport between successive compartments of the Golgi appartus: Asymmetric properties of donor and acceptor activities in a cell-free system
    • Balch, W. E. and Rothman, J. E. (1985). Characterization of protein transport between successive compartments of the Golgi appartus: asymmetric properties of donor and acceptor activities in a cell-free system. Arch. Biochem. Biophys. 240, 413-425.
    • (1985) Arch. Biochem. Biophys. , vol.240 , pp. 413-425
    • Balch, W.E.1    Rothman, J.E.2
  • 5
    • 0029082330 scopus 로고
    • Cytotrophoblast cells: A barrier to maternofetal transmission of passive immunity?
    • Bright, N. A. and Ockleford, C. D. (1995). Cytotrophoblast cells: a barrier to maternofetal transmission of passive immunity? J. Histochem. Cytochem 43, 933-944.
    • (1995) J. Histochem. Cytochem , vol.43 , pp. 933-944
    • Bright, N.A.1    Ockleford, C.D.2
  • 6
    • 85177155547 scopus 로고
    • Role for phosphatidylinositol 3-kinase in the sorting and transport of newly synthesized lysosomal enzymes in mammalian cells
    • Brown, W. J., Emr, S. D., Plutner, H. and Balch, W. E. (1995). Role for phosphatidylinositol 3-kinase in the sorting and transport of newly synthesized lysosomal enzymes in mammalian cells. J Cell Biol. 130, 797-805.
    • (1995) J Cell Biol. , vol.130 , pp. 797-805
    • Brown, W.J.1    Emr, S.D.2    Plutner, H.3    Balch, W.E.4
  • 7
    • 0028979563 scopus 로고
    • Phosphatidylinositol 3-kinase regulation of fluid phase endocytosis
    • Clague, M., Thorpe, C. and Jones, A. T. (1995). Phosphatidylinositol 3-kinase regulation of fluid phase endocytosis. FEBS Letts 367, 272-274.
    • (1995) FEBS Letts , vol.367 , pp. 272-274
    • Clague, M.1    Thorpe, C.2    Jones, A.T.3
  • 8
    • 0028260280 scopus 로고
    • Inhibition of the translocation of GLUT1 and GLUT4 in 3T3-L1 cells by the phosphtidylinositol 3-kinase inhibitor, wortmannin
    • Clarke, J. F., Young, P. W., Yonezawa, K., Kasuga, M. and Holman, G. D. (1994). Inhibition of the translocation of GLUT1 and GLUT4 in 3T3-L1 cells by the phosphtidylinositol 3-kinase inhibitor, wortmannin. Biochem. J. 300, 631-635
    • (1994) Biochem. J. , vol.300 , pp. 631-635
    • Clarke, J.F.1    Young, P.W.2    Yonezawa, K.3    Kasuga, M.4    Holman, G.D.5
  • 9
    • 0002968981 scopus 로고
    • Dissection of endosomes
    • (ed. C. Steer and J. Hannover), Cambridge University Press, Cambridge and New York
    • Courtoy, P. J. (1991) Dissection of endosomes. In Intracellular Trafficking of Proteins (ed. C. Steer and J. Hannover), pp. 103-156 Cambridge University Press, Cambridge and New York.
    • (1991) Intracellular Trafficking of Proteins , pp. 103-156
    • Courtoy, P.J.1
  • 10
    • 0028850452 scopus 로고
    • Wortmannin and its structural analogue demethoxyviridin inhibit stimulated phospholipase A2 activity in Swiss 3T3 cells. Wortmannin is not a specific inhibitor of phosphatidylinositol 3-kinase
    • Cross, M. J., Stewart, A., Hodgkin, M. N., Kerr, D. J. and Wakelam, M. J. O. (1995). Wortmannin and its structural analogue demethoxyviridin inhibit stimulated phospholipase A2 activity in Swiss 3T3 cells. Wortmannin is not a specific inhibitor of phosphatidylinositol 3-kinase. J. Biol. Chem. 270, 25352-25355.
    • (1995) J. Biol. Chem. , vol.270 , pp. 25352-25355
    • Cross, M.J.1    Stewart, A.2    Hodgkin, M.N.3    Kerr, D.J.4    Wakelam, M.J.O.5
  • 11
    • 0029123267 scopus 로고
    • Wortmannin causes mis-targeting of procathepsin D. Evidence for the involvement of a phosphatidylinositol 3-kinase in vesicular transport to lysosomes
    • Davidson, H. (1995). Wortmannin causes mis-targeting of procathepsin D. Evidence for the involvement of a phosphatidylinositol 3-kinase in vesicular transport to lysosomes. J. Cell Biol. 130, 197-805.
    • (1995) J. Cell Biol. , vol.130 , pp. 197-805
    • Davidson, H.1
  • 12
    • 0024241414 scopus 로고
    • Sorting of mannose 6-phosphate receptors and lysosmal membrane proteins in endocytic vesicles
    • Geuze, H. J., Stoorvogel, W., Strous, G., Slot, S. W., Bleekemolen, S. J. and Mellman, I. (1988). Sorting of mannose 6-phosphate receptors and lysosmal membrane proteins in endocytic vesicles. J. Cell Biol. 107, 2491-2501.
    • (1988) J. Cell Biol. , vol.107 , pp. 2491-2501
    • Geuze, H.J.1    Stoorvogel, W.2    Strous, G.3    Slot, S.W.4    Bleekemolen, S.J.5    Mellman, I.6
  • 13
    • 0025287536 scopus 로고
    • Characterization and cloning of lgp110, a lysosomal membrane glycoprotein from mouse and rat cells
    • Granger, B. L., Green, S. A., Gabel, C. A., Howe, C. L., Mellman, I. and Helenius, A. (1990). Characterization and cloning of lgp110, a lysosomal membrane glycoprotein from mouse and rat cells J. Biol. Chem. 265, 12036-12043.
    • (1990) J. Biol. Chem. , vol.265 , pp. 12036-12043
    • Granger, B.L.1    Green, S.A.2    Gabel, C.A.3    Howe, C.L.4    Mellman, I.5    Helenius, A.6
  • 14
    • 0023839303 scopus 로고
    • The mannose 6-phosphate receptor and the biogenesis of lysosomes
    • Griffiths, G., Hoflack, B., Simons, K., Mellman, I. and Kornfeld, S. (1988). The mannose 6-phosphate receptor and the biogenesis of lysosomes. Cell 52, 329-341.
    • (1988) Cell , vol.52 , pp. 329-341
    • Griffiths, G.1    Hoflack, B.2    Simons, K.3    Mellman, I.4    Kornfeld, S.5
  • 15
    • 0025240118 scopus 로고
    • Characterization of the cation-independent mannose-6-phosphate receptor enriched prelysosomal compartment in NRK cells
    • Griffiths, G., Matteoni, R., Back, R. and Hoflack, B. (1990) Characterization of the cation-independent mannose-6-phosphate receptor enriched prelysosomal compartment in NRK cells. J. Cell Sci. 95, 441-461.
    • (1990) J. Cell Sci. , vol.95 , pp. 441-461
    • Griffiths, G.1    Matteoni, R.2    Back, R.3    Hoflack, B.4
  • 16
    • 0025817708 scopus 로고
    • The arguments for pre-existing early and late endosomes
    • Griffiths, G. and Gruenberg, J. (1991). The arguments for pre-existing early and late endosomes. Trends Cell Biol. 1, 5-9.
    • (1991) Trends Cell Biol. , vol.1 , pp. 5-9
    • Griffiths, G.1    Gruenberg, J.2
  • 18
    • 0023655624 scopus 로고
    • Production and characterization of monoclonal antibodies to insulin secretory granule membranes
    • Grimaldi, K. A., Hutton, J. C. and Siddle, K. (1987). Production and characterization of monoclonal antibodies to insulin secretory granule membranes. Biochem. J. 245, 557-566.
    • (1987) Biochem. J. , vol.245 , pp. 557-566
    • Grimaldi, K.A.1    Hutton, J.C.2    Siddle, K.3
  • 19
    • 0027396163 scopus 로고
    • The motif tyr-X-X-hydrophobic residue mediates lysosomal membrane targeting of lysosome-associated membrane protein 1
    • Guarnieri, F. G., Arterburn, L. M., Penno, M. B., Cha, Y. and August, J. T. (1993). The motif tyr-X-X-hydrophobic residue mediates lysosomal membrane targeting of lysosome-associated membrane protein 1. J. Biol. Chem. 268, 1941-1946.
    • (1993) J. Biol. Chem. , vol.268 , pp. 1941-1946
    • Guarnieri, F.G.1    Arterburn, L.M.2    Penno, M.B.3    Cha, Y.4    August, J.T.5
  • 20
    • 0028862325 scopus 로고
    • Wortmannin, an inhibitor of phosphoinositide 3-kinase, inhibits transcytosis in polarized epithelial cells
    • Hansen, S. H., Olsson, A. and Casanova, J. E. (1995). Wortmannin, an inhibitor of phosphoinositide 3-kinase, inhibits transcytosis in polarized epithelial cells. J. Biol. Chem. 270, 28425-28432.
    • (1995) J. Biol. Chem. , vol.270 , pp. 28425-28432
    • Hansen, S.H.1    Olsson, A.2    Casanova, J.E.3
  • 22
    • 0027640355 scopus 로고
    • Antigen processing and intracellular traffic of antigens and MHC molecules
    • Harding, C. V. and Geuze, H. J. (1993). Antigen processing and intracellular traffic of antigens and MHC molecules. Curr. Opin. Cell Biol. 5. 596-605
    • (1993) Curr. Opin. Cell Biol. , vol.5 , pp. 596-605
    • Harding, C.V.1    Geuze, H.J.2
  • 23
    • 0026545549 scopus 로고
    • Transport of the lysosomal membrane glycoprotein lgp120 (lgp-A) to lysosomes does not require appearance on the plasma membrane
    • Harter, C. and Mellman, I. (1992). Transport of the lysosomal membrane glycoprotein lgp120 (lgp-A) to lysosomes does not require appearance on the plasma membrane. J. Cell Biol. 117, 311-325.
    • (1992) J. Cell Biol. , vol.117 , pp. 311-325
    • Harter, C.1    Mellman, I.2
  • 24
    • 0025200830 scopus 로고
    • Charcterization of VPS34, a gene required for vacuolar protein sorting and vacuole segregation in Saccharomyces cerevisiae
    • Herman, P. K. and Emr, S. D. (1990). Charcterization of VPS34, a gene required for vacuolar protein sorting and vacuole segregation in Saccharomyces cerevisiae. Mol Cell. Biol 10, 6742-6754.
    • (1990) Mol Cell. Biol , vol.10 , pp. 6742-6754
    • Herman, P.K.1    Emr, S.D.2
  • 25
    • 0024504568 scopus 로고
    • Isolation and sequencing of a cDNA clone encoding the 107 kDa sialoglycoprotein in rat liver membranes
    • Himeno, M., Noguchi, Y., Sasaki, H., Tanaka, Y., Furuno, K., Kono, A., Sakaki, Y. and Kato, K. (1989). Isolation and sequencing of a cDNA clone encoding the 107 kDa sialoglycoprotein in rat liver membranes. FEBS Letts. 244, 351-356.
    • (1989) FEBS Letts. , vol.244 , pp. 351-356
    • Himeno, M.1    Noguchi, Y.2    Sasaki, H.3    Tanaka, Y.4    Furuno, K.5    Kono, A.6    Sakaki, Y.7    Kato, K.8
  • 27
    • 0028232868 scopus 로고
    • Okadaic acid treatment leads to a fragmentation of the trans-Golgi network and an increase in expression of TGN38 at the cell surface
    • Horn, M. and Banting, G. (1994). Okadaic acid treatment leads to a fragmentation of the trans-Golgi network and an increase in expression of TGN38 at the cell surface. Biochem J. 301, 69-73.
    • (1994) Biochem J. , vol.301 , pp. 69-73
    • Horn, M.1    Banting, G.2
  • 28
    • 2142856613 scopus 로고
    • Derived protein sequence, oligosaccharides, and membrane insertion of the 120-kDa lysosomal membrane glycoprotein (lgp120): Identification of a highly conserved family of lysosomal membrane glycoproteins
    • Howe, C. L., Granger, B. L., Hull, M., Green, S. A., Gabel, C. A., Helenius, A. and Mellman, I. (1988) Derived protein sequence, oligosaccharides, and membrane insertion of the 120-kDa lysosomal membrane glycoprotein (lgp120): Identification of a highly conserved family of lysosomal membrane glycoproteins. Proc. Nat. Acad Sci. USA 85, 7577-7581.
    • (1988) Proc. Nat. Acad Sci. USA , vol.85 , pp. 7577-7581
    • Howe, C.L.1    Granger, B.L.2    Hull, M.3    Green, S.A.4    Gabel, C.A.5    Helenius, A.6    Mellman, I.7
  • 29
    • 0028126073 scopus 로고
    • Evidence for retrograde traffic between terminal lysosomes and the prelysosomal/late endosome compartment
    • Jahraus, A., Storrie, B., Griffiths, G. and Desjardins, M. (1994). Evidence for retrograde traffic between terminal lysosomes and the prelysosomal/late endosome compartment. J. Cell Sci. 107, 145-157.
    • (1994) J. Cell Sci. , vol.107 , pp. 145-157
    • Jahraus, A.1    Storrie, B.2    Griffiths, G.3    Desjardins, M.4
  • 30
    • 0028351218 scopus 로고
    • Disruption of PDGF receptor trafficking by mutation of its PI-3 kinase binding sites
    • Joly, M., Kazlauskas, A., Fay, F. S. and Corvera, S. (1994). Disruption of PDGF receptor trafficking by mutation of its PI-3 kinase binding sites. Science 263, 684-687.
    • (1994) Science , vol.263 , pp. 684-687
    • Joly, M.1    Kazlauskas, A.2    Fay, F.S.3    Corvera, S.4
  • 31
    • 0029058288 scopus 로고
    • Phosphatidylinositol 3-kinase activity is required at a postendocytic step in platelet-derived growth factor receptor trafficking
    • Joly, M., Kazlauskas, A. and Corvera, S. (1995). Phosphatidylinositol 3-kinase activity is required at a postendocytic step in platelet-derived growth factor receptor trafficking. J. Biol. Chem. 270, 13225-13230.
    • (1995) J. Biol. Chem. , vol.270 , pp. 13225-13230
    • Joly, M.1    Kazlauskas, A.2    Corvera, S.3
  • 32
    • 0029151540 scopus 로고
    • Phosphatidylinositol 3-kinase activity is required for early endosome fusion
    • Jones, A. T. and Clague, M. (1995). Phosphatidylinositol 3-kinase activity is required for early endosome fusion. Biochem J 311, 31-34
    • (1995) Biochem J , vol.311 , pp. 31-34
    • Jones, A.T.1    Clague, M.2
  • 34
    • 0022572229 scopus 로고
    • Trafficking of lysosomal enzymes in normal and disease states
    • Kornfeld, S. (1986). Trafficking of lysosomal enzymes in normal and disease states. J. Clin. Invest. 77, 1-6.
    • (1986) J. Clin. Invest. , vol.77 , pp. 1-6
    • Kornfeld, S.1
  • 36
    • 0026472647 scopus 로고
    • The trans-Golgi network can be dissected structurally and functionally from the cisternae of the Golgi complex by brefeldin A
    • Ladinsky, M. S. and Howell, K. E. (1992). The trans-Golgi network can be dissected structurally and functionally from the cisternae of the Golgi complex by brefeldin A Eur. J. Cell Biol 59, 92-105.
    • (1992) Eur. J. Cell Biol , vol.59 , pp. 92-105
    • Ladinsky, M.S.1    Howell, K.E.2
  • 39
    • 0023644927 scopus 로고
    • Cycling of the integral membrane glycoprotein, LEP100 between plasma membrane and lysosomes: Kinetic and morphological analysis
    • Lippincott-Schwartz, J. and Fambrough, D. (1987). Cycling of the integral membrane glycoprotein, LEP100 between plasma membrane and lysosomes: kinetic and morphological analysis. Cell 49, 669-677.
    • (1987) Cell , vol.49 , pp. 669-677
    • Lippincott-Schwartz, J.1    Fambrough, D.2
  • 40
    • 0025148186 scopus 로고
    • Identification, sequencing and expression of an integral membrane protein of the trans-Golgi network (TGN38)
    • Luzio, J. P., Brake, B., Banting, G., Howell, K. E., Braghetta, P. and Stanley, K. K. (1990). Identification, sequencing and expression of an integral membrane protein of the trans-Golgi network (TGN38) Biochem. J. 270, 97-102.
    • (1990) Biochem. J. , vol.270 , pp. 97-102
    • Luzio, J.P.1    Brake, B.2    Banting, G.3    Howell, K.E.4    Braghetta, P.5    Stanley, K.K.6
  • 41
    • 1842369773 scopus 로고
    • Lysosomes
    • (ed. J. Kendrew), Blackwell Science, Ltd, Oxford, UK
    • Luzio, J. P. (1994). Lysosomes. In The Encyclopaedia of Molecular Biology (ed. J. Kendrew), pp. 597-600. Blackwell Science, Ltd, Oxford, UK
    • (1994) The Encyclopaedia of Molecular Biology , pp. 597-600
    • Luzio, J.P.1
  • 42
    • 0027243406 scopus 로고
    • Sorting of membrane components from endosomes and subsequent recycling to the cell surface occurs by a bulk flow process
    • Mayor, S., Presley, J. F. and Maxfield, F. R. (1993). Sorting of membrane components from endosomes and subsequent recycling to the cell surface occurs by a bulk flow process. J. Cell Biol. 121, 127-1269.
    • (1993) J. Cell Biol. , vol.121 , pp. 127-1269
    • Mayor, S.1    Presley, J.F.2    Maxfield, F.R.3
  • 44
    • 0028017706 scopus 로고
    • Lysosomes can fuse with a late endosomal compartment in a cell-free system from rat liver
    • Mullock, B. M., Perez, J. H., Kuwana, T., Gray, S. R. and Luzio, J. P. (1994). Lysosomes can fuse with a late endosomal compartment in a cell-free system from rat liver. J. Cell Biol. 126, 1173-1182.
    • (1994) J. Cell Biol. , vol.126 , pp. 1173-1182
    • Mullock, B.M.1    Perez, J.H.2    Kuwana, T.3    Gray, S.R.4    Luzio, J.P.5
  • 45
    • 0027997975 scopus 로고
    • +-ATPase-defective yeast: Identification of six new END genes
    • +-ATPase-defective yeast: identification of six new END genes. J. Cell Biol. 127, 373-386.
    • (1994) J. Cell Biol. , vol.127 , pp. 373-386
    • Munn, A.L.1    Riezman, H.2
  • 46
    • 0025808286 scopus 로고
    • Maturation models for endosome and lysosome biogenesis
    • Murphy, R. F. (1991). Maturation models for endosome and lysosome biogenesis. Trends Cell Biol. 1, 77-82.
    • (1991) Trends Cell Biol. , vol.1 , pp. 77-82
    • Murphy, R.F.1
  • 47
    • 0024423420 scopus 로고
    • Isolation and sequencing of a cDNA clone encoding a 96 kDa sialoglycoprotein in rat liver lysosomal membranes
    • Noguchi, Y., Himeno, M., Sasaki, H., Tanaka, Y., Kono, A., Sakaki, Y. and Kato, K. (1989). Isolation and sequencing of a cDNA clone encoding a 96 kDa sialoglycoprotein in rat liver lysosomal membranes. Biochem. Biophys. Res. Commun. 164, 1113-1120.
    • (1989) Biochem. Biophys. Res. Commun. , vol.164 , pp. 1113-1120
    • Noguchi, Y.1    Himeno, M.2    Sasaki, H.3    Tanaka, Y.4    Kono, A.5    Sakaki, Y.6    Kato, K.7
  • 48
    • 0028146616 scopus 로고
    • Blockage of chemotactic peptide-induced stimulation of neutrophils by wortmannin as a result of selective inhibition of phosphatidylinositol 3-kinase
    • Okada, T., Sakuma, L., Fukui, Y., Hazeki, O. and Ui, M. (1994). Blockage of chemotactic peptide-induced stimulation of neutrophils by wortmannin as a result of selective inhibition of phosphatidylinositol 3-kinase. J. Biol. Chem. 269, 3563-3567.
    • (1994) J. Biol. Chem. , vol.269 , pp. 3563-3567
    • Okada, T.1    Sakuma, L.2    Fukui, Y.3    Hazeki, O.4    Ui, M.5
  • 49
    • 0023856926 scopus 로고
    • The human cation-independent mannose 6-phosphate receptor
    • Oshima, A., Nolan, C. M., Kyle, J. W., Grubb, J. H. and Sly, W. S. (1988) The human cation-independent mannose 6-phosphate receptor. J. Biol. Chem. 263, 2553-2562.
    • (1988) J. Biol. Chem. , vol.263 , pp. 2553-2562
    • Oshima, A.1    Nolan, C.M.2    Kyle, J.W.3    Grubb, J.H.4    Sly, W.S.5
  • 51
    • 0023373003 scopus 로고
    • The endosomal concentration of a mannose-6-phosphate receptor is unchanged in the absence of ligand synthesis
    • Pfeffer, S. R. (1987). The endosomal concentration of a mannose-6-phosphate receptor is unchanged in the absence of ligand synthesis. J. Cell Biol. 105, 229-234.
    • (1987) J. Cell Biol. , vol.105 , pp. 229-234
    • Pfeffer, S.R.1
  • 52
    • 0027945432 scopus 로고
    • 3-methyladenine inhibits transport from late endosomes to lysosomes in cultured rat and mouse fibroblasts
    • Punnonen, E.-L., Marjomaki, V. S. and Reunanen, H. (1994). 3-methyladenine inhibits transport from late endosomes to lysosomes in cultured rat and mouse fibroblasts Eur. J. Cell Biol. 65, 14-25.
    • (1994) Eur. J. Cell Biol. , vol.65 , pp. 14-25
    • Punnonen, E.-L.1    Marjomaki, V.S.2    Reunanen, H.3
  • 53
    • 0026570788 scopus 로고
    • Perturbation of the morphology of the trans-Golgi network following brefeldin a treatment: Redistribution of a TGN-specific integral membrane protein, TGN38
    • Reaves, B. and Banting, G. (1992). Perturbation of the morphology of the trans-Golgi network following brefeldin A treatment: Redistribution of a TGN-specific integral membrane protein, TGN38. J. Cell Biol. 116, 85-94.
    • (1992) J. Cell Biol. , vol.116 , pp. 85-94
    • Reaves, B.1    Banting, G.2
  • 54
    • 0027447921 scopus 로고
    • Effects of brefeldin a upon recycling between the trans-Golgi network and the cell surface in NRK cells
    • Reaves, B., Horn, M. and Banting, G. (1993). Effects of brefeldin A upon recycling between the trans-Golgi network and the cell surface in NRK cells. Mol. Biol Cell. 4, 93-105.
    • (1993) Mol. Biol Cell. , vol.4 , pp. 93-105
    • Reaves, B.1    Horn, M.2    Banting, G.3
  • 55
    • 0028224561 scopus 로고
    • Lysosome biogenesis requires Rab9 function and receptor recycling from endosomes to the trans-Golgi network
    • Riederer, M. A., Soldati, T., Shapiro, A. D., Lin, J. and Pfeffer, S. R. (1994). Lysosome biogenesis requires Rab9 function and receptor recycling from endosomes to the trans-Golgi network. J. Cell Biol. 125, 573-582.
    • (1994) J. Cell Biol. , vol.125 , pp. 573-582
    • Riederer, M.A.1    Soldati, T.2    Shapiro, A.D.3    Lin, J.4    Pfeffer, S.R.5
  • 56
    • 0029075197 scopus 로고
    • Inhibitors of phosphoinositide 3-kinase block exocytosis but not endocytosis of transferrin receptors in 3T3-L1 adipocytes
    • Shepherd, P. R., Soos, M. A. and Siddle, K. (1995). Inhibitors of phosphoinositide 3-kinase block exocytosis but not endocytosis of transferrin receptors in 3T3-L1 adipocytes. Biochem Biophys. Res. Commun. 211, 535-539.
    • (1995) Biochem Biophys. Res. Commun. , vol.211 , pp. 535-539
    • Shepherd, P.R.1    Soos, M.A.2    Siddle, K.3
  • 57
    • 0343113545 scopus 로고
    • The use of Protein A-colloidal gold (PAG) complexes as immunolabels in ultrathin frozen sections
    • (ed. A. C Cuello), John Wiley & Sons, Chichester
    • Slot, J. W. and Geuze, H. J. (1983). The use of Protein A-colloidal gold (PAG) complexes as immunolabels in ultrathin frozen sections In Immunohistochemistry (ed. A. C Cuello), pp. 323-346. John Wiley & Sons, Chichester
    • (1983) Immunohistochemistry , pp. 323-346
    • Slot, J.W.1    Geuze, H.J.2
  • 58
    • 0021806048 scopus 로고
    • A new method of preparing gold probes for multiple-labeling cytochemistry
    • Slot, J. W. and Geuze, H. J. (1985) A new method of preparing gold probes for multiple-labeling cytochemistry. Eur. J. Cell Biol. 38, 87-93.
    • (1985) Eur. J. Cell Biol. , vol.38 , pp. 87-93
    • Slot, J.W.1    Geuze, H.J.2
  • 59
    • 0027639720 scopus 로고
    • Genetic and biochemical studies of protein sorting to the yeast vacuole
    • Stack, J. H. and Emr, S. D. (1993). Genetic and biochemical studies of protein sorting to the yeast vacuole. Curr. Biol. 5, 641-646.
    • (1993) Curr. Biol. , vol.5 , pp. 641-646
    • Stack, J.H.1    Emr, S.D.2
  • 60
    • 0028110018 scopus 로고
    • Vps34p required for yeast vacuolar protein sorting is a multiple specificity kinase that exhibits both protein kinase and phosphatidylinositol-specific PI 3-kinase activities
    • Stack, J. H. and Emr, S. D. (1994) Vps34p required for yeast vacuolar protein sorting is a multiple specificity kinase that exhibits both protein kinase and phosphatidylinositol-specific PI 3-kinase activities. J. Biol. Chem. 269, 31552-31562.
    • (1994) J. Biol. Chem. , vol.269 , pp. 31552-31562
    • Stack, J.H.1    Emr, S.D.2
  • 61
    • 0027366440 scopus 로고
    • Agonist-stimulated synthesis of phosphatidylinositol (3, 4, 5)-trisphosphate: A new intracellular signalling system?
    • Stephens, L. R., Jackson, T. R. and Hawkins, P. T. (1993). Agonist-stimulated synthesis of phosphatidylinositol (3, 4, 5)-trisphosphate: a new intracellular signalling system? Bioch. Biophys. Acta. 1179, 27-75.
    • (1993) Bioch. Biophys. Acta. , vol.1179 , pp. 27-75
    • Stephens, L.R.1    Jackson, T.R.2    Hawkins, P.T.3
  • 64
    • 0018148591 scopus 로고
    • A study of positive staining of ultrathin frozen sections
    • Tokuyasu, K. T. (1978). A study of positive staining of ultrathin frozen sections. J. Ultrastructure Res. 63, 287-307.
    • (1978) J. Ultrastructure Res. , vol.63 , pp. 287-307
    • Tokuyasu, K.T.1
  • 65
    • 0028170210 scopus 로고
    • A specific inhibitor of phosphatidyl 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002)
    • Vlahos, C. J., Matter, W. F., Hui, K. Y. and Brown, R. F. (1994). A specific inhibitor of phosphatidyl 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002). J. Biol. Chem. 269, 5241-5248.
    • (1994) J. Biol. Chem. , vol.269 , pp. 5241-5248
    • Vlahos, C.J.1    Matter, W.F.2    Hui, K.Y.3    Brown, R.F.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.