-
1
-
-
0028009619
-
Gene therapy and the hemophilias (see comments)
-
Lozier JN, Brinkhous KM Gene therapy and the hemophilias (see comments). J Am Med Assoc. 271:1994;47-51.
-
(1994)
J Am Med Assoc
, vol.271
, pp. 47-51
-
-
Lozier, J.N.1
Brinkhous, K.M.2
-
3
-
-
0028935440
-
Gene therapy for the haemophilias: Current status
-
Hoeben RC Gene therapy for the haemophilias: current status. Biologicals. 23:1995;27-29.
-
(1995)
Biologicals
, vol.23
, pp. 27-29
-
-
Hoeben, R.C.1
-
4
-
-
0030611287
-
Viral vector-mediated gene therapy for hemophilia B
-
Eisensmith RC, Woo SL Viral vector-mediated gene therapy for hemophilia B. Thromb Haemost. 78:1997;24-30.
-
(1997)
Thromb Haemost
, vol.78
, pp. 24-30
-
-
Eisensmith, R.C.1
Woo, S.L.2
-
5
-
-
0030797290
-
Gene therapy for hemophilia A
-
Connelly S, Kaleko M Gene therapy for hemophilia A. Thromb Haemost. 78:1997;31-36.
-
(1997)
Thromb Haemost
, vol.78
, pp. 31-36
-
-
Connelly, S.1
Kaleko, M.2
-
6
-
-
0026548761
-
Deficiencies in factors IX and VIII: What is now known
-
Kurachi K, Yao SN, Furukawa M et al. Deficiencies in factors IX and VIII: what is now known. Hosp Pract Off Ed. 27:1992;41-51.
-
(1992)
Hosp Pract off Ed
, vol.27
, pp. 41-51
-
-
Kurachi, K.1
Yao, S.N.2
Furukawa, M.3
-
8
-
-
0025766371
-
Status of gene transfer for hemophilia A and B
-
Thompson AR Status of gene transfer for hemophilia A and B. Thromb Haemost. 66:1991;119-122.
-
(1991)
Thromb Haemost
, vol.66
, pp. 119-122
-
-
Thompson, A.R.1
-
9
-
-
0029144825
-
Progress towards gene therapy for the hemophilias
-
Thompson AR Progress towards gene therapy for the hemophilias. Thromb Haemost. 74:1995;45-51.
-
(1995)
Thromb Haemost
, vol.74
, pp. 45-51
-
-
Thompson, A.R.1
-
10
-
-
0031048881
-
Factor VIII inhibitors in previously treated haemophilia A patients with a double virus-inactivated plasma derived factor VIII concentrate
-
Peerlinck K, Arnout J, Di Giambattista M et al. Factor VIII inhibitors in previously treated haemophilia A patients with a double virus-inactivated plasma derived factor VIII concentrate. Thromb Haemost. 77:1997;80-86.
-
(1997)
Thromb Haemost
, vol.77
, pp. 80-86
-
-
Peerlinck, K.1
Arnout, J.2
Di Giambattista, M.3
-
11
-
-
1842387143
-
An alternative approach to somatic cell gene therapy
-
St. Louis D, Verma IM An alternative approach to somatic cell gene therapy. Proc Natl Acad Sci USA. 85:1988;3150-3154.
-
(1988)
Proc Natl Acad Sci USA
, vol.85
, pp. 3150-3154
-
-
St. Louis, D.1
Verma, I.M.2
-
12
-
-
0025374283
-
Phenotypic correction of factor IX deficiency in skin fibroblasts of hemophilic dogs
-
Axelrod JH, Read MS, Brinkhous KM et al. Phenotypic correction of factor IX deficiency in skin fibroblasts of hemophilic dogs. Proc Natl Acad Sci USA. 87:1990;5173-5177.
-
(1990)
Proc Natl Acad Sci USA
, vol.87
, pp. 5173-5177
-
-
Axelrod, J.H.1
Read, M.S.2
Brinkhous, K.M.3
-
13
-
-
0025306056
-
Expression of functional factor VIII in primary human skin fibroblasts after retrovirus-mediated gene transfer
-
Hoeben RC, van der Jagt RC, Schoute F et al. Expression of functional factor VIII in primary human skin fibroblasts after retrovirus-mediated gene transfer. J Biol Chem. 265:1990;7318-7323.
-
(1990)
J Biol Chem
, vol.265
, pp. 7318-7323
-
-
Hoeben, R.C.1
Van Der Jagt, R.C.2
Schoute, F.3
-
14
-
-
0025257348
-
Retroviral-mediated transfer and amplification of a functional human factor VIII gene
-
Israel DI, Kaufman RJ Retroviral-mediated transfer and amplification of a functional human factor VIII gene. Blood. 75:1990;1074-1080.
-
(1990)
Blood
, vol.75
, pp. 1074-1080
-
-
Israel, D.I.1
Kaufman, R.J.2
-
15
-
-
0025753128
-
Long-term in vivo expression of retrovirus-mediated gene transfer in mouse fibroblast implants
-
Scharfmann R, Axelrod JH, Verma IM Long-term in vivo expression of retrovirus-mediated gene transfer in mouse fibroblast implants. Proc Natl Acad Sci USA. 88:1991;4626-4630.
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, pp. 4626-4630
-
-
Scharfmann, R.1
Axelrod, J.H.2
Verma, I.M.3
-
16
-
-
0027237331
-
Sequences in the coding region of clotting factor VIII act as dominant inhibitors of RNA accumulation and protein production
-
Lynch CM, Israel DI, Kaufman RJ et al. Sequences in the coding region of clotting factor VIII act as dominant inhibitors of RNA accumulation and protein production. Hum Gene Ther. 4:1993;259-272.
-
(1993)
Hum Gene Ther
, vol.4
, pp. 259-272
-
-
Lynch, C.M.1
Israel, D.I.2
Kaufman, R.J.3
-
17
-
-
0028805939
-
Development and analysis of retroviral vectors expressing human factor VIII as a potential gene therapy for hemophilia A
-
Chuah MK, Vandendriessche T, Morgan RA Development and analysis of retroviral vectors expressing human factor VIII as a potential gene therapy for hemophilia A. Hum Gene Ther. 6:1995;1363-1377.
-
(1995)
Hum Gene Ther
, vol.6
, pp. 1363-1377
-
-
Chuah, M.K.1
Vandendriessche, T.2
Morgan, R.A.3
-
18
-
-
0028842288
-
Gene therapy for hemophilia A: Production of therapeutic levels of human factor VIII in vivo in mice
-
Dwarki VJ, Belloni P, Nijjar T et al. Gene therapy for hemophilia A: production of therapeutic levels of human factor VIII in vivo in mice. Proc Natl Acad Sci USA. 92:1995;1023-1027.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 1023-1027
-
-
Dwarki, V.J.1
Belloni, P.2
Nijjar, T.3
-
19
-
-
44049120479
-
High efficient transfer and expression of human clotting factor IX cDNA in cultured human primary skin fibroblasts from hemophilia B patient by retroviral vectors
-
Dai YF, Qiu XF, Xue JL et al. High efficient transfer and expression of human clotting factor IX cDNA in cultured human primary skin fibroblasts from hemophilia B patient by retroviral vectors. Sci China B. 35:1992;183-193.
-
(1992)
Sci China B
, vol.35
, pp. 183-193
-
-
Dai, Y.F.1
Qiu, X.F.2
Xue, J.L.3
-
20
-
-
0030832442
-
An ex vivo keratinocyte model for gene therapy of hemophilia B
-
Page SM, Brownlee GG An ex vivo keratinocyte model for gene therapy of hemophilia B. J Invest Dermatol. 109:1997;139-145.
-
(1997)
J Invest Dermatol
, vol.109
, pp. 139-145
-
-
Page, S.M.1
Brownlee, G.G.2
-
21
-
-
0029918009
-
Loss of expression of a retrovirus-transduced gene in human keratinocytes
-
Fenjves ES, Yao SN, Kurachi K et al. Loss of expression of a retrovirus-transduced gene in human keratinocytes. J Invest Dermatol. 106:1996;576-578.
-
(1996)
J Invest Dermatol
, vol.106
, pp. 576-578
-
-
Fenjves, E.S.1
Yao, S.N.2
Kurachi, K.3
-
22
-
-
0025874746
-
Expression of human factor IX in rat capillary endothelial cells: Toward somatic gene therapy for hemophilia B
-
Yao SN, Wilson JM, Nabel EG et al. Expression of human factor IX in rat capillary endothelial cells: toward somatic gene therapy for hemophilia B. Proc Natl Acad Sci USA. 88:1991;8101-8105.
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, pp. 8101-8105
-
-
Yao, S.N.1
Wilson, J.M.2
Nabel, E.G.3
-
23
-
-
0029890737
-
Delivery of human factor IX in mice by encapsulated recombinant myoblasts: A novel approach towards allogeneic gene therapy of hemophilia B
-
Hortelano G, Al Hendy A, Ofosu FA et al. Delivery of human factor IX in mice by encapsulated recombinant myoblasts: a novel approach towards allogeneic gene therapy of hemophilia B. Blood. 87:1996;5095-5103.
-
(1996)
Blood
, vol.87
, pp. 5095-5103
-
-
Hortelano, G.1
Al Hendy, A.2
Ofosu, F.A.3
-
24
-
-
0026511128
-
Expression of human factor IX in mice after injection of genetically modified myoblasts
-
Yao SN, Kurachi K Expression of human factor IX in mice after injection of genetically modified myoblasts. Proc Natl Acad Sci USA. 89:1992;3357-3361.
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 3357-3361
-
-
Yao, S.N.1
Kurachi, K.2
-
25
-
-
0028386527
-
Primary myoblast-mediated gene transfer: Persistent expression of human factor IX in mice
-
Yao SN, Smith KJ, Kurachi K Primary myoblast-mediated gene transfer: persistent expression of human factor IX in mice. Gene Ther. 1:1994;99-107.
-
(1994)
Gene Ther
, vol.1
, pp. 99-107
-
-
Yao, S.N.1
Smith, K.J.2
Kurachi, K.3
-
26
-
-
0026486612
-
Gene therapy via primary myoblasts: Long-term expression of factor IX protein following transplantation in vivo
-
Dai Y, Roman M, Naviaux RK et al. Gene therapy via primary myoblasts: long-term expression of factor IX protein following transplantation in vivo. Proc Natl Acad Sci USA. 89:1992;10892-10895.
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 10892-10895
-
-
Dai, Y.1
Roman, M.2
Naviaux, R.K.3
-
27
-
-
0029548580
-
Retroviral-mediated in vivo gene transfer into muscle cells and synthesis of human factor IX in mice
-
Baru M, Sha'anani J, Nur I Retroviral-mediated in vivo gene transfer into muscle cells and synthesis of human factor IX in mice. Intervirology. 38:1995;356-360.
-
(1995)
Intervirology
, vol.38
, pp. 356-360
-
-
Baru, M.1
Sha'Anani, J.2
Nur, I.3
-
28
-
-
0029086718
-
Expression of biologically active human factor IX in human hematopoietic cells after retroviral vector-mediated gene transduction
-
Hao QL, Malik P, Salazar R et al. Expression of biologically active human factor IX in human hematopoietic cells after retroviral vector-mediated gene transduction. Hum Gene Ther. 6:1995;873-880.
-
(1995)
Hum Gene Ther
, vol.6
, pp. 873-880
-
-
Hao, Q.L.1
Malik, P.2
Salazar, R.3
-
29
-
-
0026534020
-
Toward gene therapy in haemophilia A: Retrovirus-mediated transfer of a factor VIII gene into murine haematopoietic progenitor cells
-
Hoeben RC, Einerhand MP, Briet E et al. Toward gene therapy in haemophilia A: retrovirus-mediated transfer of a factor VIII gene into murine haematopoietic progenitor cells. Thromb Haemost. 67:1992;341-345.
-
(1992)
Thromb Haemost
, vol.67
, pp. 341-345
-
-
Hoeben, R.C.1
Einerhand, M.P.2
Briet, E.3
-
30
-
-
16944363593
-
Systemic delivery of human growth hormone or human factor IX in dogs by reintroduced genetically modified autologous bone marrow stromal cells
-
Hurwitz DR, Kirchgesser M, Merrill W et al. Systemic delivery of human growth hormone or human factor IX in dogs by reintroduced genetically modified autologous bone marrow stromal cells. Hum Gene Ther. 8:1997;137-156.
-
(1997)
Hum Gene Ther
, vol.8
, pp. 137-156
-
-
Hurwitz, D.R.1
Kirchgesser, M.2
Merrill, W.3
-
31
-
-
0030758328
-
A factor IX-deficient mouse model for hemophilia B gene therapy
-
Wang L, Zoppe M, Hackeng TM et al. A factor IX-deficient mouse model for hemophilia B gene therapy. Proc Natl Acad Sci USA. 94:1997;11563-11566.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 11563-11566
-
-
Wang, L.1
Zoppe, M.2
Hackeng, T.M.3
-
32
-
-
0030817391
-
A coagulation factor IX-deficient mouse model for human hemophilia B
-
Lin HF, Maeda N, Smithies O et al. A coagulation factor IX-deficient mouse model for human hemophilia B. Blood. 90:1997;3962-3966.
-
(1997)
Blood
, vol.90
, pp. 3962-3966
-
-
Lin, H.F.1
Maeda, N.2
Smithies, O.3
-
33
-
-
0029011723
-
Targeted disruption of the mouse factor VIII gene produces a model of haemophilia A [letter]
-
Bi L, Lawler AM, Antonorakis SE et al. Targeted disruption of the mouse factor VIII gene produces a model of haemophilia A [letter]. Nat Genet. 10:1995;119-121.
-
(1995)
Nat Genet
, vol.10
, pp. 119-121
-
-
Bi, L.1
Lawler, A.M.2
Antonorakis, S.E.3
-
34
-
-
0021318961
-
Development of factor VIII:C antibodies in dogs with hemophilia A (factor VIII:C deficiency)
-
Giles AR, Tinlin S, Hoogendoorn H et al. Development of factor VIII:C antibodies in dogs with hemophilia A (factor VIII:C deficiency). Blood. 63:1984;451-456.
-
(1984)
Blood
, vol.63
, pp. 451-456
-
-
Giles, A.R.1
Tinlin, S.2
Hoogendoorn, H.3
-
35
-
-
0024805130
-
Canine hemophilia B resulting from a point mutation with unusual consequences
-
Evans JP, Brinkhous KM, Brayer GD et al. Canine hemophilia B resulting from a point mutation with unusual consequences. Proc Natl Acad Sci USA. 86:1989;10095-10099.
-
(1989)
Proc Natl Acad Sci USA
, vol.86
, pp. 10095-10099
-
-
Evans, J.P.1
Brinkhous, K.M.2
Brayer, G.D.3
-
36
-
-
0028290674
-
In vivo production of human factor VII in mice after intrasplenic implantation of primary fibroblasts transfected by receptor-mediated, adenovirus-augmented gene delivery
-
Zatloukal K, Cotten M, Berger M et al. In vivo production of human factor VII in mice after intrasplenic implantation of primary fibroblasts transfected by receptor-mediated, adenovirus-augmented gene delivery. Proc Natl Acad Sci USA. 91:1994;5148-5152.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 5148-5152
-
-
Zatloukal, K.1
Cotten, M.2
Berger, M.3
-
37
-
-
0028076792
-
Efficient transfection of primary cells in a canine hemophilia B model using adenovirus-polylysine-DNA complexes
-
Lozier JN, Thompson AR, Hu PC et al. Efficient transfection of primary cells in a canine hemophilia B model using adenovirus-polylysine-DNA complexes. Hum Gene Ther. 5:1994;313-322.
-
(1994)
Hum Gene Ther
, vol.5
, pp. 313-322
-
-
Lozier, J.N.1
Thompson, A.R.2
Hu, P.C.3
-
38
-
-
0021750055
-
Characterization of the human factor VIII gene
-
Gitschier J, Wood WI, Goralka TM et al. Characterization of the human factor VIII gene. Nature. 312:1984;326-330.
-
(1984)
Nature
, vol.312
, pp. 326-330
-
-
Gitschier, J.1
Wood, W.I.2
Goralka, T.M.3
-
39
-
-
0021715168
-
Expression of active human factor VIII from recombinant DNA clones
-
Wood WI, Capon DJ, Simonsen CC et al. Expression of active human factor VIII from recombinant DNA clones. Nature. 312:1984;330-337.
-
(1984)
Nature
, vol.312
, pp. 330-337
-
-
Wood, W.I.1
Capon, D.J.2
Simonsen, C.C.3
-
40
-
-
0021715169
-
Molecular cloning of a cDNA encoding human antihaemophilic factor
-
Toole JJ, Knopf JL, Wozney JM et al. Molecular cloning of a cDNA encoding human antihaemophilic factor. Nature. 312:1984;342-347.
-
(1984)
Nature
, vol.312
, pp. 342-347
-
-
Toole, J.J.1
Knopf, J.L.2
Wozney, J.M.3
-
41
-
-
0022760260
-
A large region (approximately equal to 95 kDa) of human factor VIII is dispensable for in vitro procoagulant activity
-
Toole JJ, Pittman DD, Orr EC et al. A large region (approximately equal to 95 kDa) of human factor VIII is dispensable for in vitro procoagulant activity. Proc Natl Acad Sci USA. 83:1986;5939-5942.
-
(1986)
Proc Natl Acad Sci USA
, vol.83
, pp. 5939-5942
-
-
Toole, J.J.1
Pittman, D.D.2
Orr, E.C.3
-
42
-
-
0030855794
-
Second generation, B-domain deleted recombinant factor VIII
-
Berntorp E Second generation, B-domain deleted recombinant factor VIII. Thromb Haemost. 78:1997;256-260.
-
(1997)
Thromb Haemost
, vol.78
, pp. 256-260
-
-
Berntorp, E.1
-
43
-
-
0028917478
-
Expression of the blood-clotting factor-VIII cDNA is repressed by a transcriptional silencer located in its coding region
-
Hoeben RC, Fallaux FJ, Cramer SJ et al. Expression of the blood-clotting factor-VIII cDNA is repressed by a transcriptional silencer located in its coding region. Blood. 85:1995;2447-2454.
-
(1995)
Blood
, vol.85
, pp. 2447-2454
-
-
Hoeben, R.C.1
Fallaux, F.J.2
Cramer, S.J.3
-
44
-
-
0029896502
-
The human clotting factor VIII cDNA contains an autonomously replicating sequence consensus- and matrix attachment region-like sequence that binds a nuclear factor, represses heterologous gene expression, and mediates the transcriptional effects of sodium butyrate
-
Fallaux FJ, Hoeben RC, Cramer SJ et al. The human clotting factor VIII cDNA contains an autonomously replicating sequence consensus- and matrix attachment region-like sequence that binds a nuclear factor, represses heterologous gene expression, and mediates the transcriptional effects of sodium butyrate. Mol Cell Biol. 16:1996;4264-4272.
-
(1996)
Mol Cell Biol
, vol.16
, pp. 4264-4272
-
-
Fallaux, F.J.1
Hoeben, R.C.2
Cramer, S.J.3
-
45
-
-
0029098922
-
Sequences within the coding regions of clotting factor VIII and CFTR block transcriptional elongation
-
Koeberl DD, Halbert CL, Krumm A et al. Sequences within the coding regions of clotting factor VIII and CFTR block transcriptional elongation. Hum Gene Ther. 6:1995;469-479.
-
(1995)
Hum Gene Ther
, vol.6
, pp. 469-479
-
-
Koeberl, D.D.1
Halbert, C.L.2
Krumm, A.3
-
46
-
-
0024587855
-
Structure-function relationships of factor VIII elucidated through recombinant DNA technology
-
Pittman DD, Kaufman RJ Structure-function relationships of factor VIII elucidated through recombinant DNA technology. Thromb Haemost. 61:1989;161-165.
-
(1989)
Thromb Haemost
, vol.61
, pp. 161-165
-
-
Pittman, D.D.1
Kaufman, R.J.2
-
47
-
-
0028291264
-
The levels of endoplasmic reticulum proteins and ATP affect folding and secretion of selective proteins
-
Dorner AJ, Kaufman RJ The levels of endoplasmic reticulum proteins and ATP affect folding and secretion of selective proteins. Biologicals. 22:1994;103-112.
-
(1994)
Biologicals
, vol.22
, pp. 103-112
-
-
Dorner, A.J.1
Kaufman, R.J.2
-
48
-
-
0023918719
-
Synthesis, processing, and secretion of recombinant human factor VIII expressed in mammalian cells
-
Kaufman RJ, Wasley LC, Dorner AJ Synthesis, processing, and secretion of recombinant human factor VIII expressed in mammalian cells. J Biol Chem. 263:1988;6352-6362.
-
(1988)
J Biol Chem
, vol.263
, pp. 6352-6362
-
-
Kaufman, R.J.1
Wasley, L.C.2
Dorner, A.J.3
-
49
-
-
0026942117
-
Expression and structure-function properties of recombinant factor VIII
-
Kaufman RJ Expression and structure-function properties of recombinant factor VIII. Transfus Med Rev. 6:1992;235-246.
-
(1992)
Transfus Med Rev
, vol.6
, pp. 235-246
-
-
Kaufman, R.J.1
-
51
-
-
0027243120
-
Use of retroviral vectors for gene transfer and expression
-
Miller AD, Miller DG, Garcia JV et al. Use of retroviral vectors for gene transfer and expression. Methods Enzymol. 217:1993;581-599.
-
(1993)
Methods Enzymol
, vol.217
, pp. 581-599
-
-
Miller, A.D.1
Miller, D.G.2
Garcia, J.V.3
-
52
-
-
0026131054
-
Safety issues related to retroviral-mediated gene transfer in humans
-
Cornetta K, Morgan RA, Anderson WF Safety issues related to retroviral-mediated gene transfer in humans. Hum Gene Ther. 2:1991;5-14.
-
(1991)
Hum Gene Ther
, vol.2
, pp. 5-14
-
-
Cornetta, K.1
Morgan, R.A.2
Anderson, W.F.3
-
53
-
-
0027169443
-
Report to the NIH Recombinant DNA Advisory Committee on murine replication-competent retrovirus (RCR) assays (February 17, 1993)
-
Anderson WF, McGarrity GJ, Moen RC Report to the NIH Recombinant DNA Advisory Committee on murine replication-competent retrovirus (RCR) assays (February 17, 1993). Hum Gene Ther. 4:1993;311-321.
-
(1993)
Hum Gene Ther
, vol.4
, pp. 311-321
-
-
Anderson, W.F.1
McGarrity, G.J.2
Moen, R.C.3
-
54
-
-
0026641562
-
Helper virus induced T cell lymphoma in nonhuman primates after retroviral mediated gene transfer
-
Donahue RE, Kessler SW, Bodine D et al. Helper virus induced T cell lymphoma in nonhuman primates after retroviral mediated gene transfer. J Exp Med. 176:1992;1125-1135.
-
(1992)
J Exp Med
, vol.176
, pp. 1125-1135
-
-
Donahue, R.E.1
Kessler, S.W.2
Bodine, D.3
-
55
-
-
0018572719
-
Splicing and the formation of stable RNA
-
Hamer DH, Leder P Splicing and the formation of stable RNA. Cell. 18:1979;1299-1302.
-
(1979)
Cell
, vol.18
, pp. 1299-1302
-
-
Hamer, D.H.1
Leder, P.2
-
57
-
-
0030120158
-
Expression levels by retroviral vectors based upon the N2 and the MFG backbones (letter)
-
Krall W, Kohn DB Expression levels by retroviral vectors based upon the N2 and the MFG backbones (letter). Gene Ther. 3:1996;365.
-
(1996)
Gene Ther
, vol.3
, pp. 365
-
-
Krall, W.1
Kohn, D.B.2
-
58
-
-
0027283419
-
Toward gene therapy for hemophilia A: Long-term persistence of factor VIII-secreting fibroblasts after transplantation into immunodeficient mice
-
Hoeben RC, Fallaux FJ, Van Tilburg NH et al. Toward gene therapy for hemophilia A: long-term persistence of factor VIII-secreting fibroblasts after transplantation into immunodeficient mice. Hum Gene Ther. 4:1993;179-186.
-
(1993)
Hum Gene Ther
, vol.4
, pp. 179-186
-
-
Hoeben, R.C.1
Fallaux, F.J.2
Van Tilburg, N.H.3
-
59
-
-
0026625668
-
Gene therapy model for stromal precursor cells of hematopoietic microenvironment
-
Drize NJ, Surin VL, Gan OI et al. Gene therapy model for stromal precursor cells of hematopoietic microenvironment. Leukemia. 6:1992;1749-1755.
-
(1992)
Leukemia
, vol.6
, pp. 1749-1755
-
-
Drize, N.J.1
Surin, V.L.2
Gan, O.I.3
-
60
-
-
0030889354
-
Marrow stromal cells as stem cells for nonhematopoietic tissues
-
Prockop DJ Marrow stromal cells as stem cells for nonhematopoietic tissues. Science. 276:1997;71-74.
-
(1997)
Science
, vol.276
, pp. 71-74
-
-
Prockop, D.J.1
-
61
-
-
0028783263
-
Retroviral-mediated gene transfer into human bone marrow stromal cells: Studies of efficiency and in vivo survival in SCID mice
-
Li KJ, Dilber MS, Abedi MR et al. Retroviral-mediated gene transfer into human bone marrow stromal cells: studies of efficiency and in vivo survival in SCID mice. Eur J Haematol. 55:1995;302-306.
-
(1995)
Eur J Haematol
, vol.55
, pp. 302-306
-
-
Li, K.J.1
Dilber, M.S.2
Abedi, M.R.3
-
62
-
-
0028325345
-
Sustained human hematopoiesis in immunodeficient mice by cotransplantation of marrow stroma expressing human interleukin-3: Analysis of gene transduction of long-lived progenitors
-
Nolta JA, Hanley MB, Kohn DB Sustained human hematopoiesis in immunodeficient mice by cotransplantation of marrow stroma expressing human interleukin-3: analysis of gene transduction of long-lived progenitors. Blood. 83:1994;3041-3051.
-
(1994)
Blood
, vol.83
, pp. 3041-3051
-
-
Nolta, J.A.1
Hanley, M.B.2
Kohn, D.B.3
-
63
-
-
0027686238
-
In vivo gene therapy of hemophilia B: Sustained partial correction in factor IX-deficient dogs (see comments)
-
Kay MA, Rothenberg S, Landen CN et al. In vivo gene therapy of hemophilia B: sustained partial correction in factor IX-deficient dogs (see comments). Science. 262:1993;117-119.
-
(1993)
Science
, vol.262
, pp. 117-119
-
-
Kay, M.A.1
Rothenberg, S.2
Landen, C.N.3
-
64
-
-
0028158811
-
Liver-directed gene therapy: Quantitative evaluation of promoter elements by using in vivo retroviral transduction
-
Rettinger SD, Kennedy SC, Wu X et al. Liver-directed gene therapy: quantitative evaluation of promoter elements by using in vivo retroviral transduction. Proc Natl Acad Sci USA. 91:1994;1460-1464.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 1460-1464
-
-
Rettinger, S.D.1
Kennedy, S.C.2
Wu, X.3
-
65
-
-
0029862497
-
A stable human-derived packaging cell line for production of high titer retrovirus/vesicular stomatitis virus G pseudotypes
-
Ory DS, Neugeboren BA, Mulligan RC A stable human-derived packaging cell line for production of high titer retrovirus/vesicular stomatitis virus G pseudotypes. Proc Natl Acad Sci USA. 93:1996;11400-11406.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 11400-11406
-
-
Ory, D.S.1
Neugeboren, B.A.2
Mulligan, R.C.3
-
66
-
-
0030070191
-
Sensitization of cells and retroviruses to human serum by α-1,3-galactosyltransferase
-
Takeuchi Y, Porter CD, Strahan KM et al. Sensitization of cells and retroviruses to human serum by α-1,3-galactosyltransferase. Nature. 379:1996;85-88.
-
(1996)
Nature
, vol.379
, pp. 85-88
-
-
Takeuchi, Y.1
Porter, C.D.2
Strahan, K.M.3
-
67
-
-
0028839609
-
High-titer packaging cells producing recombinant retroviruses resistant to human serum
-
Cosset FL, Takeuchi Y, Battini JL et al. High-titer packaging cells producing recombinant retroviruses resistant to human serum. J Virol. 69:1995;7430-7436.
-
(1995)
J Virol
, vol.69
, pp. 7430-7436
-
-
Cosset, F.L.1
Takeuchi, Y.2
Battini, J.L.3
-
68
-
-
0029088057
-
A modified urokinase plasminogen activator induces liver regeneration without bleeding
-
Lieber A, Peeters MJ, Gown A et al. A modified urokinase plasminogen activator induces liver regeneration without bleeding. Hum Gene Ther. 6:1995;1029-1037.
-
(1995)
Hum Gene Ther
, vol.6
, pp. 1029-1037
-
-
Lieber, A.1
Peeters, M.J.2
Gown, A.3
-
69
-
-
0030452791
-
Proliferation induced by keratinocyte growth factor enhances in vivo retroviral-mediated gene transfer to mouse hepatocytes
-
Bosch A, McCray PB Jr, Chang SM et al. Proliferation induced by keratinocyte growth factor enhances in vivo retroviral-mediated gene transfer to mouse hepatocytes. J Clin Invest. 98:1996;2683-2687.
-
(1996)
J Clin Invest
, vol.98
, pp. 2683-2687
-
-
Bosch, A.1
McCray P.B., Jr.2
Chang, S.M.3
-
70
-
-
0028908522
-
Efficient in vivo transduction of the neonatal mouse liver with pseudotyped retroviral vectors
-
Miyanohara A, Yee JK, Bouic K et al. Efficient in vivo transduction of the neonatal mouse liver with pseudotyped retroviral vectors. Gene Ther. 2:1995;138-142.
-
(1995)
Gene Ther
, vol.2
, pp. 138-142
-
-
Miyanohara, A.1
Yee, J.K.2
Bouic, K.3
-
71
-
-
0029993858
-
Efficient transfer, integration, and sustained long-term expression of the transgene in adult rat brains injected with a lentiviral vector
-
Naldini L, Blomer U, Gage FH et al. Efficient transfer, integration, and sustained long-term expression of the transgene in adult rat brains injected with a lentiviral vector. Proc Natl Acad Sci USA. 93:1996;11382-11388.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 11382-11388
-
-
Naldini, L.1
Blomer, U.2
Gage, F.H.3
-
72
-
-
0029996147
-
In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector (see comments)
-
Naldini L, Blomer U, Gallay P et al. In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector (see comments). Science. 272:1996;263-267.
-
(1996)
Science
, vol.272
, pp. 263-267
-
-
Naldini, L.1
Blomer, U.2
Gallay, P.3
-
73
-
-
1842411367
-
Highly efficient and sustained gene transfer in adult neurons with a lentivirus vector
-
Blomer U, Naldini L, Kafri T et al. Highly efficient and sustained gene transfer in adult neurons with a lentivirus vector. J Virol. 71:1997;6641-6649.
-
(1997)
J Virol
, vol.71
, pp. 6641-6649
-
-
Blomer, U.1
Naldini, L.2
Kafri, T.3
-
74
-
-
0030819379
-
Multiply attenuated lentiviral vector achieves efficient gene delivery in vivo
-
Zufferey R, Nagy D, Mandel RJ et al. Multiply attenuated lentiviral vector achieves efficient gene delivery in vivo. Nat Biotechnol. 15:1997;871-875.
-
(1997)
Nat Biotechnol
, vol.15
, pp. 871-875
-
-
Zufferey, R.1
Nagy, D.2
Mandel, R.J.3
-
75
-
-
0023764622
-
Development of adenovirus vectors for the expression of heterologous genes
-
Berkner KL Development of adenovirus vectors for the expression of heterologous genes. Biotechniques. 6:1988;616-629.
-
(1988)
Biotechniques
, vol.6
, pp. 616-629
-
-
Berkner, K.L.1
-
76
-
-
0028991820
-
In vivo gene delivery and expression of physiological levels of functional human factor VIII in mice
-
Connelly S, Smith TA, Dhir G et al. In vivo gene delivery and expression of physiological levels of functional human factor VIII in mice. Hum Gene Ther. 6:1995;185-193.
-
(1995)
Hum Gene Ther
, vol.6
, pp. 185-193
-
-
Connelly, S.1
Smith, T.A.2
Dhir, G.3
-
77
-
-
0030069229
-
High-level tissue-specific expression of functional human factor VIII in mice
-
Connelly S, Gardner JM, McClelland A et al. High-level tissue-specific expression of functional human factor VIII in mice. Hum Gene Ther. 7:1996;183-195.
-
(1996)
Hum Gene Ther
, vol.7
, pp. 183-195
-
-
Connelly, S.1
Gardner, J.M.2
McClelland, A.3
-
78
-
-
0029943193
-
Sustained expression of therapeutic levels of human factor VIII in mice
-
Connelly S, Gardner JM, Lyons RM et al. Sustained expression of therapeutic levels of human factor VIII in mice. Blood. 87:1996;4671-4677.
-
(1996)
Blood
, vol.87
, pp. 4671-4677
-
-
Connelly, S.1
Gardner, J.M.2
Lyons, R.M.3
-
79
-
-
0029850534
-
Complete short-term correction of canine hemophilia A by in vivo gene therapy
-
Connelly S, Mount J, Mauser A et al. Complete short-term correction of canine hemophilia A by in vivo gene therapy. Blood. 88:1996;3846-3853.
-
(1996)
Blood
, vol.88
, pp. 3846-3853
-
-
Connelly, S.1
Mount, J.2
Mauser, A.3
-
80
-
-
0027521773
-
Adenovirus mediated expression of therapeutic plasma levels of human factor IX in mice
-
Smith TA, Mehaffey MG, Kayda DB et al. Adenovirus mediated expression of therapeutic plasma levels of human factor IX in mice. Nat Genet. 5:1993;397-402.
-
(1993)
Nat Genet
, vol.5
, pp. 397-402
-
-
Smith, T.A.1
Mehaffey, M.G.2
Kayda, D.B.3
-
81
-
-
0027389602
-
The development of homologous (canine/anti-canine) antibodies in dogs with haemophilia A (factor VIII deficiency): A 10-year longitudinal study
-
Tinlin S, Webster S, Giles AR The development of homologous (canine/anti-canine) antibodies in dogs with haemophilia A (factor VIII deficiency): a 10-year longitudinal study. Thromb Haemost. 69:1993;21-24.
-
(1993)
Thromb Haemost
, vol.69
, pp. 21-24
-
-
Tinlin, S.1
Webster, S.2
Giles, A.R.3
-
82
-
-
0028484704
-
MHC class I-restricted cytotoxic T lymphocytes to viral antigens destroy hepatocytes in mice infected with E1-deleted recombinant adenoviruses
-
Yang Y, Ertl HC, Wilson JM MHC class I-restricted cytotoxic T lymphocytes to viral antigens destroy hepatocytes in mice infected with E1-deleted recombinant adenoviruses. Immunity. 1:1994;433-442.
-
(1994)
Immunity
, vol.1
, pp. 433-442
-
-
Yang, Y.1
Ertl, H.C.2
Wilson, J.M.3
-
83
-
-
0028328261
-
Cellular immunity to viral antigens limits E1-deleted adenoviruses for gene therapy
-
Yang Y, Nunes FA, Berencsi K et al. Cellular immunity to viral antigens limits E1-deleted adenoviruses for gene therapy. Proc Natl Acad Sci USA. 91:1994;4407-4411.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 4407-4411
-
-
Yang, Y.1
Nunes, F.A.2
Berencsi, K.3
-
84
-
-
0029655456
-
Efficient dual transcomplementation of adenovirus E1 and E4 regions from a 293-derived cell line expressing a minimal E4 functional unit
-
Yeh P, Dedieu JF, Orsini C et al. Efficient dual transcomplementation of adenovirus E1 and E4 regions from a 293-derived cell line expressing a minimal E4 functional unit. J Virol. 70:1996;559-565.
-
(1996)
J Virol
, vol.70
, pp. 559-565
-
-
Yeh, P.1
Dedieu, J.F.2
Orsini, C.3
-
85
-
-
0028863880
-
Characterization of an adenovirus gene transfer vector containing an E4 deletion
-
Armentano D, Sookdeo CC, Hehir KM et al. Characterization of an adenovirus gene transfer vector containing an E4 deletion. Hum Gene Ther. 6:1995;1343-1353.
-
(1995)
Hum Gene Ther
, vol.6
, pp. 1343-1353
-
-
Armentano, D.1
Sookdeo, C.C.2
Hehir, K.M.3
-
86
-
-
0029582770
-
A packaging cell line for propagation of recombinant adenovirus vectors containing two lethal gene-region deletions
-
Wang Q, Jia XC, Finer MH A packaging cell line for propagation of recombinant adenovirus vectors containing two lethal gene-region deletions. Gene Ther. 2:1995;775-783.
-
(1995)
Gene Ther
, vol.2
, pp. 775-783
-
-
Wang, Q.1
Jia, X.C.2
Finer, M.H.3
-
87
-
-
0029959867
-
Biology of adenovirus vectors with E1 and E4 deletions for liver-directed gene therapy
-
Gao GP, Yang Y, Wilson JM Biology of adenovirus vectors with E1 and E4 deletions for liver-directed gene therapy. J Virol. 70:1996;8934-8943.
-
(1996)
J Virol
, vol.70
, pp. 8934-8943
-
-
Gao, G.P.1
Yang, Y.2
Wilson, J.M.3
-
88
-
-
0029054932
-
Rescue, propagation, and partial purification of a helper virus-dependent adenovirus vector
-
Mitani K, Graham FL, Caskey CT et al. Rescue, propagation, and partial purification of a helper virus-dependent adenovirus vector. Proc Natl Acad Sci USA. 92:1995;3854-3858.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 3854-3858
-
-
Mitani, K.1
Graham, F.L.2
Caskey, C.T.3
-
89
-
-
0029857641
-
In vivo muscle gene transfer of full-length dystrophin with an adenoviral vector that lacks all viral genes
-
Clemens PR, Kochanek S, Sunada Y et al. In vivo muscle gene transfer of full-length dystrophin with an adenoviral vector that lacks all viral genes. Gene Ther. 3:1996;965-972.
-
(1996)
Gene Ther
, vol.3
, pp. 965-972
-
-
Clemens, P.R.1
Kochanek, S.2
Sunada, Y.3
-
90
-
-
0029943155
-
A new adenoviral vector: Replacement of all viral coding sequences with 28 kb of DNA independently expressing both full-length dystrophin and β-galactosidase
-
Kochanek S, Clemens PR, Mitani K et al. A new adenoviral vector: Replacement of all viral coding sequences with 28 kb of DNA independently expressing both full-length dystrophin and β-galactosidase. Proc Natl Acad Sci USA. 93:1996;5731-5736.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 5731-5736
-
-
Kochanek, S.1
Clemens, P.R.2
Mitani, K.3
-
91
-
-
0031049699
-
Persistence in muscle of an adenoviral vector that lacks all viral genes
-
Chen HH, Mack LM, Kelly R et al. Persistence in muscle of an adenoviral vector that lacks all viral genes. Proc Natl Acad Sci USA. 94:1997;1645-1650.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 1645-1650
-
-
Chen, H.H.1
MacK, L.M.2
Kelly, R.3
-
92
-
-
0030462599
-
A helper-dependent adenovirus vector system: Removal of helper virus by Cre-mediated excision of the viral packaging signal
-
Parks RJ, Chen L, Anton M et al. A helper-dependent adenovirus vector system: removal of helper virus by Cre-mediated excision of the viral packaging signal. Proc Natl Acad Sci USA. 93:1996;13565-13570.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 13565-13570
-
-
Parks, R.J.1
Chen, L.2
Anton, M.3
-
93
-
-
0030900511
-
A helper-dependent system for adenovirus vector production helps define a lower limit for efficient DNA packaging
-
Parks RJ, Graham FL A helper-dependent system for adenovirus vector production helps define a lower limit for efficient DNA packaging. J Virol. 71:1997;3293-3298.
-
(1997)
J Virol
, vol.71
, pp. 3293-3298
-
-
Parks, R.J.1
Graham, F.L.2
-
94
-
-
0029861452
-
Recombinant adenoviruses with large deletions generated by Cre-mediated excision exhibit different biological properties compared with first-generation vectors in vitro and in vivo
-
Lieber A, He CY, Kirillova I et al. Recombinant adenoviruses with large deletions generated by Cre-mediated excision exhibit different biological properties compared with first-generation vectors in vitro and in vivo. J Virol. 70:1996;8944-8960.
-
(1996)
J Virol
, vol.70
, pp. 8944-8960
-
-
Lieber, A.1
He, C.Y.2
Kirillova, I.3
-
95
-
-
0029934048
-
Transient immunosuppression permits successful repetitive intravenous administration of an adenovirus vector
-
Smith TA, White BD, Gardner JM et al. Transient immunosuppression permits successful repetitive intravenous administration of an adenovirus vector. Gene Ther. 3:1996;496-502.
-
(1996)
Gene Ther
, vol.3
, pp. 496-502
-
-
Smith, T.A.1
White, B.D.2
Gardner, J.M.3
-
96
-
-
0029944988
-
Transient immune blockade prevents formation of neutralizing antibody to recombinant adenovirus and allows repeated gene transfer to mouse liver
-
Yang Y, Greenough K, Wilson JM Transient immune blockade prevents formation of neutralizing antibody to recombinant adenovirus and allows repeated gene transfer to mouse liver. Gene Ther. 3:1996;412-420.
-
(1996)
Gene Ther
, vol.3
, pp. 412-420
-
-
Yang, Y.1
Greenough, K.2
Wilson, J.M.3
-
97
-
-
0028978493
-
Recombinant IL-12 prevents formation of blocking IgA antibodies to recombinant adenovirus and allows repeated gene therapy to mouse lung [see comments]
-
Yang Y, Trinchieri G, Wilson JM Recombinant IL-12 prevents formation of blocking IgA antibodies to recombinant adenovirus and allows repeated gene therapy to mouse lung [see comments]. Nat Med. 1:1995;890-893.
-
(1995)
Nat Med
, vol.1
, pp. 890-893
-
-
Yang, Y.1
Trinchieri, G.2
Wilson, J.M.3
-
98
-
-
0028170362
-
Prospects for the use of adeno-associated virus as a vector for human gene therapy
-
Kotin RM Prospects for the use of adeno-associated virus as a vector for human gene therapy. Hum Gene Ther. 5:1994;793-801.
-
(1994)
Hum Gene Ther
, vol.5
, pp. 793-801
-
-
Kotin, R.M.1
-
99
-
-
0029843596
-
Efficient long-term gene transfer into muscle tissue of immunocompetent mice by adeno-associated virus vector
-
Xiao X, Li J, Samulski RJ Efficient long-term gene transfer into muscle tissue of immunocompetent mice by adeno-associated virus vector. J Virol. 70:1996;8098-8108.
-
(1996)
J Virol
, vol.70
, pp. 8098-8108
-
-
Xiao, X.1
Li, J.2
Samulski, R.J.3
-
100
-
-
0028169741
-
Long-term gene expression and phenotypic correction using adeno-associated virus vectors in the mammalian brain
-
Kaplitt MG, Leone P, Samulski RJ et al. Long-term gene expression and phenotypic correction using adeno-associated virus vectors in the mammalian brain. Nat Genet. 8:1994;148-154.
-
(1994)
Nat Genet
, vol.8
, pp. 148-154
-
-
Kaplitt, M.G.1
Leone, P.2
Samulski, R.J.3
-
101
-
-
0030997346
-
Persistent and therapeutic concentrations of human factor IX in mice after hepatic gene transfer of recombinant AAV vectors
-
Snyder RO, Miao CH, Patijn GA et al. Persistent and therapeutic concentrations of human factor IX in mice after hepatic gene transfer of recombinant AAV vectors. Nat Genet. 16:1997;270-276.
-
(1997)
Nat Genet
, vol.16
, pp. 270-276
-
-
Snyder, R.O.1
Miao, C.H.2
Patijn, G.A.3
-
102
-
-
0027133660
-
Hepatic gene therapy: Efficient gene delivery and expression in primary hepatocytes utilizing a conjugated adenovirus-DNA complex
-
Cristiano RJ, Smith LC, Kay MA et al. Hepatic gene therapy: efficient gene delivery and expression in primary hepatocytes utilizing a conjugated adenovirus-DNA complex. Proc Natl Acad Sci USA. 90:1993;11548-11552.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 11548-11552
-
-
Cristiano, R.J.1
Smith, L.C.2
Kay, M.A.3
-
104
-
-
0030962380
-
Extravascular administration of factor IX: Potential for replacement therapy of canine and human hemophilia B
-
Liles D, Landen CN, Monroe DM et al. Extravascular administration of factor IX: potential for replacement therapy of canine and human hemophilia B. Thromb Haemost. 77:1997;944-948.
-
(1997)
Thromb Haemost
, vol.77
, pp. 944-948
-
-
Liles, D.1
Landen, C.N.2
Monroe, D.M.3
-
106
-
-
0026098571
-
Inactivation of the Moloney murine leukemia virus long terminal repeat in murine fibroblast cell lines is associated with methylation and dependent on its chromosomal position
-
Hoeben RC, Migchielsen AA, van der Jagt RC et al. Inactivation of the Moloney murine leukemia virus long terminal repeat in murine fibroblast cell lines is associated with methylation and dependent on its chromosomal position. J Virol. 65:1991;904-912.
-
(1991)
J Virol
, vol.65
, pp. 904-912
-
-
Hoeben, R.C.1
Migchielsen, A.A.2
Van Der Jagt, R.C.3
-
107
-
-
43949164137
-
Long-term expression of human factor IX cDNA in rabbits
-
Zhou JM, Qiu XF, Lu DR et al. Long-term expression of human factor IX cDNA in rabbits. Sci China B. 36:1993;1333-1341.
-
(1993)
Sci China B
, vol.36
, pp. 1333-1341
-
-
Zhou, J.M.1
Qiu, X.F.2
Lu, D.R.3
-
108
-
-
43949163969
-
Stage I clinical trial of gene therapy for hemophilia B
-
Lu DR, Zhou JM, Zheng B et al. Stage I clinical trial of gene therapy for hemophilia B. Sci China B. 36:1993;1342-1351.
-
(1993)
Sci China B
, vol.36
, pp. 1342-1351
-
-
Lu, D.R.1
Zhou, J.M.2
Zheng, B.3
-
109
-
-
0030275393
-
Implantation of autologous skin fibroblast genetically modified to secrete clotting factor IX partially corrects the hemorrhagic tendencies in two hemophilia B patients
-
Qiu X, Lu D, Zhou J et al. Implantation of autologous skin fibroblast genetically modified to secrete clotting factor IX partially corrects the hemorrhagic tendencies in two hemophilia B patients. Chin Med J Engl. 109:1996;832-839.
-
(1996)
Chin Med J Engl
, vol.109
, pp. 832-839
-
-
Qiu, X.1
Lu, D.2
Zhou, J.3
-
110
-
-
0026730993
-
Circulating human or canine factor IX from retrovirally transduced primary myoblasts and established myoblast cell lines grafted into murine skeletal muscle
-
Roman M, Axelrod JH, Dai Y et al. Circulating human or canine factor IX from retrovirally transduced primary myoblasts and established myoblast cell lines grafted into murine skeletal muscle. Somat Cell Mol Genet. 18:1992;247-258.
-
(1992)
Somat Cell Mol Genet
, vol.18
, pp. 247-258
-
-
Roman, M.1
Axelrod, J.H.2
Dai, Y.3
-
111
-
-
0025160084
-
Expression of human factor IX in rabbit hepatocytes by retrovirus-mediated gene transfer: Potential for gene therapy of hemophilia B
-
Armentano D, Thompson AR, Darlington G et al. Expression of human factor IX in rabbit hepatocytes by retrovirus-mediated gene transfer: potential for gene therapy of hemophilia B. Proc Natl Acad Sci USA. 87:1990;6141-6145.
-
(1990)
Proc Natl Acad Sci USA
, vol.87
, pp. 6141-6145
-
-
Armentano, D.1
Thompson, A.R.2
Darlington, G.3
-
112
-
-
0027465539
-
Towards gene therapy for haemophilia B using primary human keratinocytes
-
Gerrard AJ, Hudson DL, Brownlee GG et al. Towards gene therapy for haemophilia B using primary human keratinocytes. Nat Genet. 3:1993;180-183.
-
(1993)
Nat Genet
, vol.3
, pp. 180-183
-
-
Gerrard, A.J.1
Hudson, D.L.2
Brownlee, G.G.3
-
113
-
-
0029955012
-
Recombinant factor IX secreted by transduced human keratinocytes is biologically active
-
Gerrard AJ, Austen DE, Brownlee GG Recombinant factor IX secreted by transduced human keratinocytes is biologically active. Br J Haematol. 95:1996;561-563.
-
(1996)
Br J Haematol
, vol.95
, pp. 561-563
-
-
Gerrard, A.J.1
Austen, D.E.2
Brownlee, G.G.3
-
114
-
-
0027257291
-
Expression of human factor IX by microencapsulated recombinant fibroblasts
-
Liu HW, Ofosu FA, Chang PL Expression of human factor IX by microencapsulated recombinant fibroblasts. Hum Gene Ther. 4:1993;291-301.
-
(1993)
Hum Gene Ther
, vol.4
, pp. 291-301
-
-
Liu, H.W.1
Ofosu, F.A.2
Chang, P.L.3
-
115
-
-
0029411921
-
Neovascularization of synthetic membranes directed by membrane microarchitecture
-
Brauker JH, Carr Brendel VE, Martinson LA et al. Neovascularization of synthetic membranes directed by membrane microarchitecture. J Biomed Mater Res. 29:1995;1517-1524.
-
(1995)
J Biomed Mater Res
, vol.29
, pp. 1517-1524
-
-
Brauker, J.H.1
Carr Brendel, V.E.2
Martinson, L.A.3
-
116
-
-
0030629554
-
Transplantation of cells in an immunoisolation device for gene therapy
-
Carr Brendel VE, Geller RL, Thomas TJ et al. Transplantation of cells in an immunoisolation device for gene therapy. Methods Mol Biol. 63:1997;373-387.
-
(1997)
Methods Mol Biol
, vol.63
, pp. 373-387
-
-
Carr Brendel, V.E.1
Geller, R.L.2
Thomas, T.J.3
-
117
-
-
0030920096
-
In vivo retrovirus-mediated gene transfer into multiple hematopoietic lineages in rabbits without preconditioning
-
Nelson DM, Metzger ME, Donahue RE et al. In vivo retrovirus-mediated gene transfer into multiple hematopoietic lineages in rabbits without preconditioning. Hum Gene Ther. 8:1997;747-754.
-
(1997)
Hum Gene Ther
, vol.8
, pp. 747-754
-
-
Nelson, D.M.1
Metzger, M.E.2
Donahue, R.E.3
-
118
-
-
0028274169
-
In vivo hepatic gene therapy: Complete albeit transient correction of factor IX deficiency in hemophilia B dogs
-
Kay MA, Landen CN, Rothenberg SR et al. In vivo hepatic gene therapy: complete albeit transient correction of factor IX deficiency in hemophilia B dogs. Proc Natl Acad Sci USA. 91:1994;2353-2357.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 2353-2357
-
-
Kay, M.A.1
Landen, C.N.2
Rothenberg, S.R.3
-
119
-
-
0028934815
-
Cellular and humoral immune responses to adenoviral vectors containing factor IX gene: Tolerization of factor IX and vector antigens allows for long-term expression
-
Dai Y, Schwarz EM, Gu D et al. Cellular and humoral immune responses to adenoviral vectors containing factor IX gene: tolerization of factor IX and vector antigens allows for long-term expression. Proc Natl Acad Sci USA. 92:1995;1401-1405.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 1401-1405
-
-
Dai, Y.1
Schwarz, E.M.2
Gu, D.3
-
120
-
-
0029154012
-
Gene therapy for hemophilia B: Host immunosuppression prolongs the therapeutic effect of adenovirus-mediated factor IX expression
-
Fang B, Eisensmith RC, Wang H et al. Gene therapy for hemophilia B: host immunosuppression prolongs the therapeutic effect of adenovirus-mediated factor IX expression. Hum Gene Ther. 6:1995;1039-1044.
-
(1995)
Hum Gene Ther
, vol.6
, pp. 1039-1044
-
-
Fang, B.1
Eisensmith, R.C.2
Wang, H.3
-
121
-
-
0029670374
-
Lack of persistence of E1-recombinant adenoviral vectors containing a temperature-sensitive E2A mutation in immunocompetent mice and hemophilia B dogs
-
Fang B, Wang H, Gordon G et al. Lack of persistence of E1-recombinant adenoviral vectors containing a temperature-sensitive E2A mutation in immunocompetent mice and hemophilia B dogs. Gene Ther. 3:1996;217-222.
-
(1996)
Gene Ther
, vol.3
, pp. 217-222
-
-
Fang, B.1
Wang, H.2
Gordon, G.3
-
122
-
-
16944362534
-
Gut epithelial cells as targets for gene therapy of hemophilia
-
Lozier JN, Yankaskas JR, Ramsey WJ et al. Gut epithelial cells as targets for gene therapy of hemophilia. Hum Gene Ther. 8:1997;1481-1490.
-
(1997)
Hum Gene Ther
, vol.8
, pp. 1481-1490
-
-
Lozier, J.N.1
Yankaskas, J.R.2
Ramsey, W.J.3
-
123
-
-
0031019819
-
Persistent expression of human clotting factor IX from mouse liver after intravenous injection of adeno-associated virus vectors
-
Koeberl DD, Alexander IE, Halbert CL et al. Persistent expression of human clotting factor IX from mouse liver after intravenous injection of adeno-associated virus vectors. Proc Natl Acad Sci USA. 94:1997;1426-1431.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 1426-1431
-
-
Koeberl, D.D.1
Alexander, I.E.2
Halbert, C.L.3
-
124
-
-
0030902985
-
Stable gene transfer and expression of human blood coagulation factor IX after intramuscular injection of recombinant adeno-associated virus
-
Herzog RW, Hagstrom JN, Kung SH et al. Stable gene transfer and expression of human blood coagulation factor IX after intramuscular injection of recombinant adeno-associated virus. Proc Natl Acad Sci USA. 94:1997;5804-5809.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 5804-5809
-
-
Herzog, R.W.1
Hagstrom, J.N.2
Kung, S.H.3
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