-
1
-
-
0021750055
-
Characterization of the human factor VIII gene
-
Gitschier J, Wood IW, Goralka TM, Wion KL, Chen EY, Eaton DH, Vehar GA. Capon DJ, Lawn RM. Characterization of the human factor VIII gene. Nature 1984; 312: 326-30.
-
(1984)
Nature
, vol.312
, pp. 326-330
-
-
Gitschier, J.1
Wood, I.W.2
Goralka, T.M.3
Wion, K.L.4
Chen, E.Y.5
Eaton, D.H.6
Vehar, G.A.7
Capon, D.J.8
Lawn, R.M.9
-
2
-
-
0021715169
-
Molecular cloning of a cDNA encoding human antihaemophilic factor
-
Toole JJ, Knopf JL, Wozney JM, Sultzman LA, Buecker JL, Pittman DD, Kaufman RJ, Brown E, Shoemaker C, Orr EC, Amphlett GW, Foster WB, Coe ML, Knutson GJ, Fass DN, Hewick RM. Molecular cloning of a cDNA encoding human antihaemophilic factor. Nature 1984; 312: 342-47.
-
(1984)
Nature
, vol.312
, pp. 342-347
-
-
Toole, J.J.1
Knopf, J.L.2
Wozney, J.M.3
Sultzman, L.A.4
Buecker, J.L.5
Pittman, D.D.6
Kaufman, R.J.7
Brown, E.8
Shoemaker, C.9
Orr, E.C.10
Amphlett, G.W.11
Foster, W.B.12
Coe, M.L.13
Knutson, G.J.14
Fass, D.N.15
Hewick, R.M.16
-
3
-
-
0021677942
-
Structure of human factor VIII
-
Vehar GA, Keyt B, Eaton D, Rodriguez H, O'Brien DP, Rotblat F, Opperman H, Keck R, Wood WI, Harkins RN, Tuddenham GD, Lawn RM, Capon DJ. Structure of human factor VIII. Nature 1984; 312: 337-42.
-
(1984)
Nature
, vol.312
, pp. 337-342
-
-
Vehar, G.A.1
Keyt, B.2
Eaton, D.3
Rodriguez, H.4
O'Brien, D.P.5
Rotblat, F.6
Opperman, H.7
Keck, R.8
Wood, W.I.9
Harkins, R.N.10
Tuddenham, G.D.11
Lawn, R.M.12
Capon, D.J.13
-
4
-
-
0025644310
-
Human recombinant DNA-derived antihemophilic factor (factor VIII) in the treatment of hemophilia A
-
Schwartz RS, Abildgaard CF, Aledort LM, Arkin S, Bloom AL, Brackmann HH, Brettler DB, Fukui H, Hilgartner MW, Inwood MJ, et al. Human recombinant DNA-derived antihemophilic factor (factor VIII) in the treatment of hemophilia A. N Engl J Med 1990; 323: 1800-5.
-
(1990)
N Engl J Med
, vol.323
, pp. 1800-1805
-
-
Schwartz, R.S.1
Abildgaard, C.F.2
Aledort, L.M.3
Arkin, S.4
Bloom, A.L.5
Brackmann, H.H.6
Brettler, D.B.7
Fukui, H.8
Hilgartner, M.W.9
Inwood, M.J.10
-
5
-
-
0026939127
-
Current status of clinical studies of recombinant factor VIII (Recombinate) in patients with hemophilia A
-
Bray GL. Current status of clinical studies of recombinant factor VIII (Recombinate) in patients with hemophilia A. Transfus Med Rev 1992; 6: 252-55.
-
(1992)
Transfus Med Rev
, vol.6
, pp. 252-255
-
-
Bray, G.L.1
-
6
-
-
0027473752
-
Kogenate Previously Untreated Patient Study Group. Recombinant factor VIII for the treatment of previously untreated patients with hemophilia A
-
Lusher JM, Arkin S, Abildgaard CF, Schwartz RS, Kogenate Previously Untreated Patient Study Group. Recombinant factor VIII for the treatment of previously untreated patients with hemophilia A. N Engl J Med 1993; 328: 453-59.
-
(1993)
N Engl J Med
, vol.328
, pp. 453-459
-
-
Lusher, J.M.1
Arkin, S.2
Abildgaard, C.F.3
Schwartz, R.S.4
-
7
-
-
85005490325
-
Considerations for current and future management of haemophilia and its complications
-
Lusher JM. Considerations for current and future management of haemophilia and its complications. Haemophilia 1995; 1: 2-10.
-
(1995)
Haemophilia
, vol.1
, pp. 2-10
-
-
Lusher, J.M.1
-
8
-
-
0028266130
-
A multicenter study of recombinant factor VIII (Recombinate): Safety, efficacy and inhibitor risk in previously untreated patients with hemophilia A
-
Bray GL, Gomperts ED, Courter S, Gruppe R, Gordon EM, Manco-Johnson M, Shapiro A, Scheibel E, White G, the Recombinate Study Group. A multicenter study of recombinant factor VIII (Recombinate): Safety, efficacy and inhibitor risk in previously untreated patients with hemophilia A. Blood 1994; 83: 2428-35.
-
(1994)
Blood
, vol.83
, pp. 2428-2435
-
-
Bray, G.L.1
Gomperts, E.D.2
Courter, S.3
Gruppe, R.4
Gordon, E.M.5
Manco-Johnson, M.6
Shapiro, A.7
Scheibel, E.8
White, G.9
-
9
-
-
0026548917
-
Incidence of development of factor VIII and factor IX inhibitors in haemophiliacs
-
Ehrenforth S, Kreutz W, Scharrer I, Linde R, Funk M, Gungor T, Krackhardt B, Kornhuber B. Incidence of development of factor VIII and factor IX inhibitors in haemophiliacs. Lancet 1992; 339: 594-98.
-
(1992)
Lancet
, vol.339
, pp. 594-598
-
-
Ehrenforth, S.1
Kreutz, W.2
Scharrer, I.3
Linde, R.4
Funk, M.5
Gungor, T.6
Krackhardt, B.7
Kornhuber, B.8
-
10
-
-
0027257566
-
Frequency of inhibitor development in haemophiliacs treated with low purity factor VIII
-
Addiego J, Kasper C, Abildgaard C, Hilgartner M, Lusher J, Glader B, Aledort L. Frequency of inhibitor development in haemophiliacs treated with low purity factor VIII. Lancet 1993; 342: 462-64.
-
(1993)
Lancet
, vol.342
, pp. 462-464
-
-
Addiego, J.1
Kasper, C.2
Abildgaard, C.3
Hilgartner, M.4
Lusher, J.5
Glader, B.6
Aledort, L.7
-
11
-
-
0029887182
-
Recombinant clotting factor concentrates
-
Baillière Tindall, W.B. Saunders Company Ltd, London
-
Lusher JM. Recombinant clotting factor concentrates. In: Ballière's Clinical Haematology. Baillière Tindall, W.B. Saunders Company Ltd, London 1996; 9: 291-303.
-
(1996)
Ballière's Clinical Haematology
, vol.9
, pp. 291-303
-
-
Lusher, J.M.1
-
12
-
-
0002715639
-
Detection of human parvovirus B19 DNA by polymerase chain reaction in different factor VIII concentrates: Correlation with infectivity? XXII Int Congr Wld Fed Hemophilia, Dublin, 1996
-
abstract
-
Laurian Y, Dussaix E, Rothschild C, Mauser-Bunschoten EP, Gomperts ED, d'Oiron R, Tchernia G. Detection of human parvovirus B19 DNA by polymerase chain reaction in different factor VIII concentrates: Correlation with infectivity? XXII Int Congr Wld Fed Hemophilia, Dublin, 1996. Haemophilia 1996; 2 (Suppl 1): 97 (abstract).
-
(1996)
Haemophilia
, vol.2
, Issue.1 SUPPL.
, pp. 97
-
-
Laurian, Y.1
Dussaix, E.2
Rothschild, C.3
Mauser-Bunschoten, E.P.4
Gomperts, E.D.5
D'Oiron, R.6
Tchernia, G.7
-
13
-
-
0344450955
-
Parvovirus B19 DNA is frequently present in recombinant coagulation factor VIII products
-
Eis-Hübinger AM, Sasowski U, Brackmann HH, Kaiser R, Matz B, Schneweis KE. Parvovirus B19 DNA is frequently present in recombinant coagulation factor VIII products. Thromb Haemost 1996; 76: 1120.
-
(1996)
Thromb Haemost
, vol.76
, pp. 1120
-
-
Eis-Hübinger, A.M.1
Sasowski, U.2
Brackmann, H.H.3
Kaiser, R.4
Matz, B.5
Schneweis, K.E.6
-
14
-
-
0001933829
-
Virus safety considerations for recombinant factor VIII (rFVIII, Kogenate)
-
Arnold D. Virus safety considerations for recombinant factor VIII (rFVIII, Kogenate). Haemophilia 1995; 1 (Suppl 2): 22-23.
-
(1995)
Haemophilia
, vol.1
, Issue.2 SUPPL.
, pp. 22-23
-
-
Arnold, D.1
-
15
-
-
0029133142
-
Novel forms of B-domain-deleted recombinant factor VIII molecules. Construction and biochemical characterization
-
Lind P, Larsson K, Spira J, Sydow-Bäckman M, Almstedt A, Gray E, Sandberg H. Novel forms of B-domain-deleted recombinant factor VIII molecules. Construction and biochemical characterization. Eur J Biochem 1995; 232: 19-27.
-
(1995)
Eur J Biochem
, vol.232
, pp. 19-27
-
-
Lind, P.1
Larsson, K.2
Spira, J.3
Sydow-Bäckman, M.4
Almstedt, A.5
Gray, E.6
Sandberg, H.7
-
16
-
-
0001064088
-
Glycosylation pattern of a B-domain-deleted recombinant factor VIII molecule (r-VIII SQ)
-
Jerusalem, abstract
-
Sandberg H, Brandt J, Ålin P, Strömberg S, Gray E, Bartfai J, Castro V. Glycosylation pattern of a B-domain-deleted recombinant factor VIII molecule (r-VIII SQ). XVth Cong Int Soc Thromb Haemost, Jerusalem, 1995 (abstract).
-
(1995)
XVth Cong Int Soc Thromb Haemost
-
-
Sandberg, H.1
Brandt, J.2
Ålin, P.3
Strömberg, S.4
Gray, E.5
Bartfai, J.6
Castro, V.7
-
17
-
-
1842277677
-
Biochemical characteristics of a recombinant human factor VIII with a deleted B-domain
-
Athens, abstract
-
Sandberg H, Bartfai J. Brandt J, Holmquist L, Kenne L, Lewin M, Lind P, Nilsson B, Sandberg M, Sebring S, Strömberg S, Ålin P. Biochemical characteristics of a recombinant human factor VIII with a deleted B-domain. XXth Int Congr Wld Fed Hemophilia, Athens, 1992 (abstract).
-
(1992)
XXth Int Congr Wld Fed Hemophilia
-
-
Sandberg, H.1
Bartfai, J.2
Brandt, J.3
Holmquist, L.4
Kenne, L.5
Lewin, M.6
Lind, P.7
Nilsson, B.8
Sandberg, M.9
Sebring, S.10
Strömberg, S.11
Ålin, P.12
-
18
-
-
1842278657
-
Prophylactic treatment with a B-domain-deleted recombinant factor VIII (r-VIII SQ) in previously treated patients with severe haemophilia A
-
Jerusalem, abstract
-
Berntorp E, Brackmann HH, Dechavanne M, Gazengel Cl, Johnsson H, Laurian Y, Tengborn L, Stahl C, Holm R. Prophylactic treatment with a B-domain-deleted recombinant factor VIII (r-VIII SQ) in previously treated patients with severe haemophilia A. XVth Congr Int Soc Thromb Haemost, Jerusalem, 1995 (abstract).
-
(1995)
XVth Congr Int Soc Thromb Haemost
-
-
Berntorp, E.1
Brackmann, H.H.2
Dechavanne, M.3
Gazengel, Cl.4
Johnsson, H.5
Laurian, Y.6
Tengborn, L.7
Stahl, C.8
Holm, R.9
-
19
-
-
1842266959
-
Comparison of factor VIII:C methods and reagents in the assay of factor VIII concentrates and post-injection patient plasma samples
-
Mexico City, abstract
-
Oswaldsson U, Frank L, Sandberg H, Mikaelsson M. Comparison of factor VIII:C methods and reagents in the assay of factor VIII concentrates and post-injection patient plasma samples. XXI Int Congr Wld Fed Hemophilia, Mexico City, 1994 (abstract).
-
(1994)
XXI Int Congr Wld Fed Hemophilia
-
-
Oswaldsson, U.1
Frank, L.2
Sandberg, H.3
Mikaelsson, M.4
-
20
-
-
1842350607
-
Stability and compatibility of reconstituted recombinant factor VIII SQ (r-VIII SQ) in a system for continuous infusion
-
Dublin
-
Juhlin F, Moberg U, Oswaldsson U, Renlund S, Mikaelsson M. Stability and compatibility of reconstituted recombinant factor VIII SQ (r-VIII SQ) in a system for continuous infusion. XXII Int Congr Wld Fed Haemophilia, Dublin, 1996.
-
(1996)
XXII Int Congr Wld Fed Haemophilia
-
-
Juhlin, F.1
Moberg, U.2
Oswaldsson, U.3
Renlund, S.4
Mikaelsson, M.5
-
21
-
-
0004787122
-
The purification process for recombinant factor VIII SQ
-
Jerusalem, abstract
-
Smeds A-L, Ljungqvist Å, Östlin A, Ljungquist C, Gaal A, Sandberg H, Rosenquist J, Mikaelsson M. The purification process for recombinant factor VIII SQ. XVth Congr Int Soc Thromb Haemost, Jerusalem, 1995 (abstract).
-
(1995)
XVth Congr Int Soc Thromb Haemost
-
-
Smeds, A.-L.1
Ljungqvist, Å.2
Östlin, A.3
Ljungquist, C.4
Gaal, A.5
Sandberg, H.6
Rosenquist, J.7
Mikaelsson, M.8
-
22
-
-
26544443914
-
Development of a freeze-dried HSA-free formulation of a new recombinant factor VIII derivative, r-VIII SQ
-
New York, abstract
-
Österberg T, Fatouros A. Development of a freeze-dried HSA-free formulation of a new recombinant factor VIII derivative, r-VIII SQ. XIVth Congr Int Soc Thromb Haemost, New York, 1993 (abstract).
-
(1993)
XIVth Congr Int Soc Thromb Haemost
-
-
Österberg, T.1
Fatouros, A.2
-
24
-
-
1842350575
-
Preclinical characterization of recombinant factor VIII SQ
-
Mexico City, abstract
-
Mikaelsson M, Eriksson B, Ljungqvist Å, Löfström A, Sandberg H, Wikén M, Österberg T. Preclinical characterization of recombinant factor VIII SQ. XXI Int Congr Wld Fed Hemophilia, Mexico City, 1994 (abstract).
-
(1994)
XXI Int Congr Wld Fed Hemophilia
-
-
Mikaelsson, M.1
Eriksson, B.2
Ljungqvist, Å.3
Löfström, A.4
Sandberg, H.5
Wikén, M.6
Österberg, T.7
-
25
-
-
0019973659
-
A canine model of hemophilic (factor VIII:C deficiency) bleeding
-
Giles AR, Tinlin S, Greenwood R. A canine model of hemophilic (factor VIII:C deficiency) bleeding. Blood 1982; 60: 727-30.
-
(1982)
Blood
, vol.60
, pp. 727-730
-
-
Giles, A.R.1
Tinlin, S.2
Greenwood, R.3
-
26
-
-
0025847974
-
The design and analysis of half-life and recovery studies for factor VIII and IX
-
Morfini M, Lee M, Messori A. The design and analysis of half-life and recovery studies for factor VIII and IX. Thromb Haemost 1991; 66: 384-86.
-
(1991)
Thromb Haemost
, vol.66
, pp. 384-386
-
-
Morfini, M.1
Lee, M.2
Messori, A.3
-
27
-
-
1842310325
-
Deletion of the B-domain in a recombinant factor VIII (r-VIII SQ) does not affect its main kinetic properties. Three pharmacokinetic studies in 36 patients with severe haemophilia A
-
Jerusalem, abstract
-
Berntorp E, Johnsson H, Tengborn L, Fijnvandraat K, Peters M, ten Cate JW, Savidge G, Ståhl C, Holm R. Deletion of the B-domain in a recombinant factor VIII (r-VIII SQ) does not affect its main kinetic properties. Three pharmacokinetic studies in 36 patients with severe haemophilia A. XVth Congr Int Soc Thromb Haemost, Jerusalem, 1995 (abstract).
-
(1995)
XVth Congr Int Soc Thromb Haemost
-
-
Berntorp, E.1
Johnsson, H.2
Tengborn, L.3
Fijnvandraat, K.4
Peters, M.5
Ten Cate, J.W.6
Savidge, G.7
Ståhl, C.8
Holm, R.9
-
28
-
-
0028810479
-
Inter-individual variation in half-life of infused recombinant factor VIII is related to pre-infusion von Willeband factor antigen levels
-
Fijnvandraat K, Peters M, Ten Cate KW. Inter-individual variation in half-life of infused recombinant factor VIII is related to pre-infusion von Willeband factor antigen levels. Br J Haematol 1995; 91: 474-76.
-
(1995)
Br J Haematol
, vol.91
, pp. 474-476
-
-
Fijnvandraat, K.1
Peters, M.2
Ten Cate, K.W.3
-
29
-
-
1842380618
-
Clinical efficacy of clotting factor concentrates: Survival, recovery and hemostatic capacity
-
Smit Sibinga T, Das PM, Mannucci PM, eds. Kluwer Academic Publishers
-
Nilsson IM, Berntorp E. Clinical efficacy of clotting factor concentrates: Survival, recovery and hemostatic capacity. In: Coagulation and Blood Transfusion. Smit Sibinga T, Das PM, Mannucci PM, eds. Kluwer Academic Publishers 1991, pp 193-206.
-
(1991)
Coagulation and Blood Transfusion
, pp. 193-206
-
-
Nilsson, I.M.1
Berntorp, E.2
-
30
-
-
1842346740
-
One-year use of recombinant factor VIII SQ (r-VIII SQ, Pharmacia, Sweden) in patients with haemophilia A. XXII Ing Congr Wld Fed Hemophilia, Dublin, 1996
-
abstract
-
Tusell Puigbert J, Spira J. One-year use of recombinant factor VIII SQ (r-VIII SQ, Pharmacia, Sweden) in patients with haemophilia A. XXII Ing Congr Wld Fed Hemophilia, Dublin, 1996. Hemophilia 1996; 2 (Suppl 1): 37 (abstract).
-
(1996)
Hemophilia
, vol.2
, Issue.1 SUPPL.
, pp. 37
-
-
Tusell Puigbert, J.1
Spira, J.2
-
31
-
-
84980270757
-
Guidelines for therapy and optimal dosages of coagulation factors for treatment of bleeding and surgery in haemophilia
-
Rickard KA. Guidelines for therapy and optimal dosages of coagulation factors for treatment of bleeding and surgery in haemophilia. Haemopilia 1995;1 (Suppl 1): 8-13.
-
(1995)
Haemopilia
, vol.1
, Issue.1 SUPPL.
, pp. 8-13
-
-
Rickard, K.A.1
-
32
-
-
1842400091
-
Management of surgery in patients with haemophilia A using recombinant factor VIII (r-VIII SQ, Pharmacia, Sweden). XXII Int Congr Wld Fed Haemophilia, Dublin, 1996
-
abstract
-
Hay CRM, Spira J. Management of surgery in patients with haemophilia A using recombinant factor VIII (r-VIII SQ, Pharmacia, Sweden). XXII Int Congr Wld Fed Haemophilia, Dublin, 1996. Haemophilia 1996; 2 (Suppl 1): 53 (abstract).
-
(1996)
Haemophilia
, vol.2
, Issue.1 SUPPL.
, pp. 53
-
-
Hay, C.R.M.1
Spira, J.2
-
33
-
-
1842357549
-
Results from the first year of a recombinant factor VIII SQ (r-VIII SQ, Pharmacia, Sweden) study in previously untreated patients with haemophilia A. XXII Int Congr Wld Fed Hemophilia, Dublin, 1996
-
abstract
-
Kreuz W, Spira J. Results from the first year of a recombinant factor VIII SQ (r-VIII SQ, Pharmacia, Sweden) study in previously untreated patients with haemophilia A. XXII Int Congr Wld Fed Hemophilia, Dublin, 1996. Haemophilia 1996; 2 (Suppl 1): 37 (abstract).
-
(1996)
Haemophilia
, vol.2
, Issue.1 SUPPL.
, pp. 37
-
-
Kreuz, W.1
Spira, J.2
|