메뉴 건너뛰기




Volumn 7, Issue 2, 1996, Pages 183-195

High-level tissue-specific expression of functional human factor VIII in mice

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD CLOTTING FACTOR 8; VIRUS VECTOR;

EID: 0030069229     PISSN: 10430342     EISSN: None     Source Type: Journal    
DOI: 10.1089/hum.1996.7.2-183     Document Type: Article
Times cited : (72)

References (65)
  • 1
    • 0022817678 scopus 로고
    • Cellular promoters incorporated into the adenovirus genome: Effects of viral regulatory elements on transcription rates and cell specificity of albumin and β-globin promoters
    • BABISS, L.E., FRIEDMAN, J.M., and DARNELL, J.E., JR. (1986). Cellular promoters incorporated into the adenovirus genome: Effects of viral regulatory elements on transcription rates and cell specificity of albumin and β-globin promoters. Mol. Cell. Biol. 6, 3798-3806.
    • (1986) Mol. Cell. Biol. , vol.6 , pp. 3798-3806
    • Babiss, L.E.1    Friedman, J.M.2    Darnell Jr., J.E.3
  • 2
    • 0028914687 scopus 로고
    • Strain related variations in adenovirally mediated transgene expression from mouse hepatocytes in vivo: Comparisons between immunocompetent and immunodeficient inbred strains
    • BARR, D., TUBB, J., FERGUSON, D., SCARIA, A., LIEBER, A., WILSON, C., PERKINS, J., and KAY, M.A. (1995). Strain related variations in adenovirally mediated transgene expression from mouse hepatocytes in vivo: Comparisons between immunocompetent and immunodeficient inbred strains. Gene Ther. 2, 151-155.
    • (1995) Gene Ther. , vol.2 , pp. 151-155
    • Barr, D.1    Tubb, J.2    Ferguson, D.3    Scaria, A.4    Lieber, A.5    Wilson, C.6    Perkins, J.7    Kay, M.A.8
  • 4
    • 0022296676 scopus 로고
    • Purified human factor VIII procoagulant protein: Comparative hemostatic response after infusions into hemophilic and von Willebrand disease dogs
    • BRINKHOUS, K.M., SANDBERG, H., GARRIS, J.B., MATTSSON, C., PALM, M., GRIGGS, T., and READ, M.S. (1985). Purified human factor VIII procoagulant protein: Comparative hemostatic response after infusions into hemophilic and von Willebrand disease dogs. Proc. Natl. Acad. Sci. USA 82, 8752-8756.
    • (1985) Proc. Natl. Acad. Sci. USA , vol.82 , pp. 8752-8756
    • Brinkhous, K.M.1    Sandberg, H.2    Garris, J.B.3    Mattsson, C.4    Palm, M.5    Griggs, T.6    Read, M.S.7
  • 6
    • 0023790358 scopus 로고
    • Comparison of intron-dependent and intron-independent gene expression
    • BUCHMAN, A.R., and BERG, P. (1988). Comparison of intron-dependent and intron-independent gene expression. Mol. Cell Biol. 8, 4395-4405.
    • (1988) Mol. Cell Biol. , vol.8 , pp. 4395-4405
    • Buchman, A.R.1    Berg, P.2
  • 7
    • 0025906388 scopus 로고
    • A generic intron increases gene expression in transgenic mice
    • CHOI, T., HUANG, M., GORMAN, C., and JAENISCH, R. (1991). A generic intron increases gene expression in transgenic mice. Mol. Cell Biol. 11, 3070-3074.
    • (1991) Mol. Cell Biol. , vol.11 , pp. 3070-3074
    • Choi, T.1    Huang, M.2    Gorman, C.3    Jaenisch, R.4
  • 8
    • 0023147790 scopus 로고
    • Expression of active human blood clotting factor IX in transgenic mice: Use of a cDNA with complete mRNA sequence
    • CHOO, K.H., RAPHAEL, K., McADAM, W., and PETERSON, M.G. (1987). Expression of active human blood clotting factor IX in transgenic mice: Use of a cDNA with complete mRNA sequence. Nucleic Acids Res. 15, 871-884.
    • (1987) Nucleic Acids Res. , vol.15 , pp. 871-884
    • Choo, K.H.1    Raphael, K.2    McAdam, W.3    Peterson, M.G.4
  • 10
    • 0025813282 scopus 로고
    • The extracellular matrix coordinately modulates liver transcription factors and hepatocyte morphology
    • DIPERSIO, C.M., JACKSON, D.A., and ZARET, K.S. (1991). The extracellular matrix coordinately modulates liver transcription factors and hepatocyte morphology. Mol. Cell. Biol. 11, 4405-4414.
    • (1991) Mol. Cell. Biol. , vol.11 , pp. 4405-4414
    • Dipersio, C.M.1    Jackson, D.A.2    Zaret, K.S.3
  • 11
    • 0028291264 scopus 로고
    • The levels of endoplasmic reticulum proteins and ATP affect folding and secretion of selective proteins
    • DORNER, A.J., and KAUFMAN, R.J. (1994). The levels of endoplasmic reticulum proteins and ATP affect folding and secretion of selective proteins. Biologicals 22, 103-112.
    • (1994) Biologicals , vol.22 , pp. 103-112
    • Dorner, A.J.1    Kaufman, R.J.2
  • 12
    • 0026511824 scopus 로고
    • Overexpression of GRP78 mitigates stress induction of glucose regulated proteins and blocks secretion of selective proteins in Chinese hamster ovary cells
    • DORNER, A.J., WASLEY, L.C., and KAUFMAN, R.J. (1992). Overexpression of GRP78 mitigates stress induction of glucose regulated proteins and blocks secretion of selective proteins in Chinese hamster ovary cells. EMBO J. 11, 1563-1571.
    • (1992) EMBO J. , vol.11 , pp. 1563-1571
    • Dorner, A.J.1    Wasley, L.C.2    Kaufman, R.J.3
  • 13
    • 0023979999 scopus 로고
    • Heterogenous nuclear ribonucleoprotein particles and the pathway of mRNA formation
    • DREYFUSS, G., SWANSON, M.S., and PINOL-ROMA, S. (1988). Heterogenous nuclear ribonucleoprotein particles and the pathway of mRNA formation. Trends Biochem. Sci. 13, 86-91.
    • (1988) Trends Biochem. Sci. , vol.13 , pp. 86-91
    • Dreyfuss, G.1    Swanson, M.S.2    Pinol-Roma, S.3
  • 16
    • 0022814975 scopus 로고
    • Cellular promoters incorporated into the adenovirus genome: Cell specificity of albumin and immunoglobulin expression
    • FRIEDMAN, J.M., BABISS, L.E., CLAYTON, D.F., and DARNELL, J.E., JR. (1986). Cellular promoters incorporated into the adenovirus genome: Cell specificity of albumin and immunoglobulin expression. Mol. Cell. Biol. 6, 3791-3797.
    • (1986) Mol. Cell. Biol. , vol.6 , pp. 3791-3797
    • Friedman, J.M.1    Babiss, L.E.2    Clayton, D.F.3    Darnell Jr., J.E.4
  • 17
    • 0019973659 scopus 로고
    • A canine model of hemophilic (factor VIII:C deficiency) bleeding
    • GILES, A.R., TINLIN, S., and GREENWOOD, R. (1982). A canine model of hemophilic (factor VIII:C deficiency) bleeding. Blood 60, 727-731.
    • (1982) Blood , vol.60 , pp. 727-731
    • Giles, A.R.1    Tinlin, S.2    Greenwood, R.3
  • 18
    • 0022893665 scopus 로고
    • Tissue-specific in vitro transcription from the mouse albumin promoter
    • GORSKI, K., CARNEIRO, M., and SHIBLER, U. (1986). Tissue-specific in vitro transcription from the mouse albumin promoter. Cell 47, 767-776.
    • (1986) Cell , vol.47 , pp. 767-776
    • Gorski, K.1    Carneiro, M.2    Shibler, U.3
  • 19
    • 0027992935 scopus 로고
    • Quantitative evaluation of liver-specific promoters from retroviral vectors after in vivo transduction of hepatocytes
    • HAFENRICHTER, D.G., WU, X., RETTINGER, S.D., KENNEDY, S.C., FLYE, M.W., and PONDER, K.P. (1994). Quantitative evaluation of liver-specific promoters from retroviral vectors after in vivo transduction of hepatocytes. Blood 10, 3394-3404.
    • (1994) Blood , vol.10 , pp. 3394-3404
    • Hafenrichter, D.G.1    Wu, X.2    Rettinger, S.D.3    Kennedy, S.C.4    Flye, M.W.5    Ponder, K.P.6
  • 21
    • 0028124788 scopus 로고
    • Expression of a thyroid hormone-responsive recombinant gene introduced into adult mice livers by replication-defective adenovirus can be regulated by endogenous thyroid hormone receptor
    • HAYASHI, Y., DEPAOLI, A.M., BURANT, C.F., and REFETOFF, S. (1994). Expression of a thyroid hormone-responsive recombinant gene introduced into adult mice livers by replication-defective adenovirus can be regulated by endogenous thyroid hormone receptor. J. Biol. Chem. 269, 23872-23875.
    • (1994) J. Biol. Chem. , vol.269 , pp. 23872-23875
    • Hayashi, Y.1    Depaoli, A.M.2    Burant, C.F.3    Refetoff, S.4
  • 23
    • 0026534020 scopus 로고
    • Toward gene therapy in haemophilia A: Retrovirus-mediated transfer of a factor VIII gene into murine haematopoietic progenitor cells
    • HOEBEN, R.C., EINERHAND, M.P., BRIET, E., VAN ORMONDT, H., VALERIO, D., and VAN DER EB, A.J. (1992). Toward gene therapy in haemophilia A: retrovirus-mediated transfer of a factor VIII gene into murine haematopoietic progenitor cells. Thromb. Haemost. 67, 341-345.
    • (1992) Thromb. Haemost. , vol.67 , pp. 341-345
    • Hoeben, R.C.1    Einerhand, M.P.2    Briet, E.3    Van Ormondt, H.4    Valerio, D.5    Van Der Eb, A.J.6
  • 24
    • 0027283419 scopus 로고
    • Toward gene therapy for hemophilia A: Long-term persistence of factor VIII-secreting fibroblasts after transplantation into immunodeficient mice
    • HOEBEN, R.C., FALLAUX, F.J., VAN TILBURG, N.H., CRAMER, S.J., VAN ORMONDT, H., BRIET, E., and VAN DER EB, A.J. (1993). Toward gene therapy for hemophilia A: Long-term persistence of factor VIII-secreting fibroblasts after transplantation into immunodeficient mice. Hum. Gene Ther. 4, 179-186.
    • (1993) Hum. Gene Ther. , vol.4 , pp. 179-186
    • Hoeben, R.C.1    Fallaux, F.J.2    Van Tilburg, N.H.3    Cramer, S.J.4    Van Ormondt, H.5    Briet, E.6    Van Der Eb, A.J.7
  • 25
    • 0028917478 scopus 로고
    • Expression of the blood-clotting factor-VIII cDNA is repressed by a transcriptional silencer located in its coding region
    • HOEBEN, R.C., FALLAUX, F.J., CRAMER, S.J., VAN DEN WOLLENBERG, J.M., VAN ORMONDT, H., BRIET, E., and VAN DER EB, A.J. (1995). Expression of the blood-clotting factor-VIII cDNA is repressed by a transcriptional silencer located in its coding region. Blood 85, 2447-2454.
    • (1995) Blood , vol.85 , pp. 2447-2454
    • Hoeben, R.C.1    Fallaux, F.J.2    Cramer, S.J.3    Van Den Wollenberg, J.M.4    Van Ormondt, H.5    Briet, E.6    Van Der Eb, A.J.7
  • 27
    • 0025269031 scopus 로고
    • Intervening sequences increase efficiency of RNA 3′ processing and accumulation of cytoplasmic RNA
    • HUANG, M.T.F., and GORMAN, C.M. (1990). Intervening sequences increase efficiency of RNA 3′ processing and accumulation of cytoplasmic RNA. Nucleic Acids Res. 18, 937-947.
    • (1990) Nucleic Acids Res. , vol.18 , pp. 937-947
    • Huang, M.T.F.1    Gorman, C.M.2
  • 28
    • 0027258140 scopus 로고
    • Hypercholesterolemia in low density lipoprotein receptor knockout mice and its reversal by adenovirus-mediated gene delivery
    • ISHIBASHI, S., BROWN, M.S., GOLDSTEIN, J.L., GERARD, R.D., HAMMER, E.R., and HERZ, J. (1993). Hypercholesterolemia in low density lipoprotein receptor knockout mice and its reversal by adenovirus-mediated gene delivery. J. Clin. Invest. 92, 883-893.
    • (1993) J. Clin. Invest. , vol.92 , pp. 883-893
    • Ishibashi, S.1    Brown, M.S.2    Goldstein, J.L.3    Gerard, R.D.4    Hammer, E.R.5    Herz, J.6
  • 29
    • 0025257348 scopus 로고
    • Retroviral-mediated transfer and amplification of a functional human factor VIII gene
    • ISRAEL, D.I., and KAUFMAN, R.J. (1990). Retroviral-mediated transfer and amplification of a functional human factor VIII gene. Blood 75, 1074-1080.
    • (1990) Blood , vol.75 , pp. 1074-1080
    • Israel, D.I.1    Kaufman, R.J.2
  • 30
    • 0025063533 scopus 로고
    • Characterization of recombinant human Factor IX expressed in transgenic mice and in derived trans-immortalized hepatic cell lines
    • JALLAT, S., PERRAUND, F., DALEMANS, W., BALLAND, A., DIETERIE, A., FAURE, T., MEULIEN, P., and PAVIRANI, A. (1990). Characterization of recombinant human Factor IX expressed in transgenic mice and in derived trans-immortalized hepatic cell lines. EMBO J. 9, 3295-3301.
    • (1990) EMBO J. , vol.9 , pp. 3295-3301
    • Jallat, S.1    Perraund, F.2    Dalemans, W.3    Balland, A.4    Dieterie, A.5    Faure, T.6    Meulien, P.7    Pavirani, A.8
  • 31
    • 0024597022 scopus 로고
    • Effect of von Willebrand factor coexpression on the synthesis and secretion of factor VIII in Chinese hamster ovary cells
    • KAUFMAN, R.J., WASLEY, L.C., DAVIES, M.V., WISE, R.J., ISRAEL, D.I., and DORNER, A.J. (1989). Effect of von Willebrand factor coexpression on the synthesis and secretion of factor VIII in Chinese hamster ovary cells. Mol. Cell. Biol. 9, 1233-1242.
    • (1989) Mol. Cell. Biol. , vol.9 , pp. 1233-1242
    • Kaufman, R.J.1    Wasley, L.C.2    Davies, M.V.3    Wise, R.J.4    Israel, D.I.5    Dorner, A.J.6
  • 32
    • 0026762462 scopus 로고
    • Biological regulation of factor VIII activity
    • KAUFMAN, R.J. (1992). Biological regulation of factor VIII activity. Annu. Rev. Med. 43, 325-339.
    • (1992) Annu. Rev. Med. , vol.43 , pp. 325-339
    • Kaufman, R.J.1
  • 33
    • 0023918719 scopus 로고
    • Synthesis, processing, and secretion of recombinant human factor VIII expressed in mammalian cells
    • KAUFMAN, R.J., WASLEY, L.C., and DORNER, A.J. (1988). Synthesis, processing, and secretion of recombinant human factor VIII expressed in mammalian cells. J. Biol. Chem. 263, 6352-6362.
    • (1988) J. Biol. Chem. , vol.263 , pp. 6352-6362
    • Kaufman, R.J.1    Wasley, L.C.2    Dorner, A.J.3
  • 35
    • 0029098922 scopus 로고
    • Sequences within the coding regions of clotting factor VIII and CFTR block transcriptional elongation
    • KOEBERL, D.D., HALBERT, C.L., KRUMM, A., and MILLER, A.D. (1995). Sequences within the coding regions of clotting factor VIII and CFTR block transcriptional elongation. Hum. Gene Ther. 6, 469-479.
    • (1995) Hum. Gene Ther. , vol.6 , pp. 469-479
    • Koeberl, D.D.1    Halbert, C.L.2    Krumm, A.3    Miller, A.D.4
  • 37
    • 0028900484 scopus 로고
    • Role of intron I in expression of the human factor IX gene
    • KURACHI, S., HITOMI, Y., FURUKAWA, M., and KURACHI, K. (1995). Role of intron I in expression of the human factor IX gene. J. Biol. Chem. 270, 5276-5281.
    • (1995) J. Biol. Chem. , vol.270 , pp. 5276-5281
    • Kurachi, S.1    Hitomi, Y.2    Furukawa, M.3    Kurachi, K.4
  • 38
    • 0024009589 scopus 로고
    • The mouse albumin promoter and a distal upstream site are simultaneously DNase I hypersensitive in liver chromatin and bind similar liver-abundant factors in vitro
    • LIU, J.-K., BERGMAN, Y., and ZARET, K.S. (1988). The mouse albumin promoter and a distal upstream site are simultaneously DNase I hypersensitive in liver chromatin and bind similar liver-abundant factors in vitro. Genes & Dev. 2, 528-541.
    • (1988) Genes & Dev. , vol.2 , pp. 528-541
    • Liu, J.-K.1    Bergman, Y.2    Zaret, K.S.3
  • 39
    • 0026089359 scopus 로고
    • Extracellular signals that regulate liver transcription factors during hepatic differentiation in vitro
    • LIU, J.-K., DIPERSIO, C.M., and ZARET, K.S. (1991). Extracellular signals that regulate liver transcription factors during hepatic differentiation in vitro. Mol. Cell. Biol. 11, 773-784.
    • (1991) Mol. Cell. Biol. , vol.11 , pp. 773-784
    • Liu, J.-K.1    Dipersio, C.M.2    Zaret, K.S.3
  • 40
  • 41
    • 0027237331 scopus 로고
    • Sequences in the coding region of clotting factor VIII act as dominant inhibitors of RNA accumulation and protein production
    • LYNCH, C.M., ISRAEL, D.I., KAUFMAN, R.J., and MILLER, A.D. (1993). Sequences in the coding region of clotting factor VIII act as dominant inhibitors of RNA accumulation and protein production. Hum. Gene Ther. 4, 259-272.
    • (1993) Hum. Gene Ther. , vol.4 , pp. 259-272
    • Lynch, C.M.1    Israel, D.I.2    Kaufman, R.J.3    Miller, A.D.4
  • 42
    • 0028240520 scopus 로고
    • Immune tolerance in hemophilia-principal results from the International Registry. Report of the factor VIII and IX Subcommitte
    • MARIANI, G., GHIRARDINI, A., and BELLOCCO, R. (1994). Immune tolerance in hemophilia-principal results from the International Registry. Report of the factor VIII and IX Subcommitte. Thromb. Haemost. 72, 155-158.
    • (1994) Thromb. Haemost. , vol.72 , pp. 155-158
    • Mariani, G.1    Ghirardini, A.2    Bellocco, R.3
  • 44
    • 0023339694 scopus 로고
    • An albumin enhancer located 10 kb upstream functions along with its promoter to direct efficient, liver-specific expression in transgenic mice
    • PINKERT, C.A., ORNITZ, D.M., BRINSTER, R.L., and PALMITER, R.D. (1987). An albumin enhancer located 10 kb upstream functions along with its promoter to direct efficient, liver-specific expression in transgenic mice. Genes & Dev. 1, 268-276.
    • (1987) Genes & Dev. , vol.1 , pp. 268-276
    • Pinkert, C.A.1    Ornitz, D.M.2    Brinster, R.L.3    Palmiter, R.D.4
  • 45
    • 0027527981 scopus 로고
    • Site directed mutagenesis and expression of coagulation factors VIII and V in mammalian cells
    • PITTMAN, D.D., and KAUFMAN, R.J. (1993). Site directed mutagenesis and expression of coagulation factors VIII and V in mammalian cells. Methods Enzymol. 222, 236-260.
    • (1993) Methods Enzymol. , vol.222 , pp. 236-260
    • Pittman, D.D.1    Kaufman, R.J.2
  • 46
    • 0027319588 scopus 로고
    • Biochemical, Immunological, and in vivo functional characterization of B-domain-deleted factor VIII
    • PITTMAN, D.D., ALDERMAN, E.M., TOMKINSON, K.N., WANG, J.H., GILES, A.R., and KAUFMAN, R.J. (1993). Biochemical, Immunological, and in vivo functional characterization of B-domain-deleted factor VIII. Blood 81, 2925-2935.
    • (1993) Blood , vol.81 , pp. 2925-2935
    • Pittman, D.D.1    Alderman, E.M.2    Tomkinson, K.N.3    Wang, J.H.4    Giles, A.R.5    Kaufman, R.J.6
  • 47
    • 0021659730 scopus 로고
    • Transcriptional and posttranscriptional control of specific messenger RNAs in adult and embryonic liver
    • POWELL, D.J., FRIEDMAN, J.M., OULETTE, A.J., KRAUTER, K.S., and DARNELL, J.E., JR. (1984). Transcriptional and posttranscriptional control of specific messenger RNAs in adult and embryonic liver. J. Mol. Biol. 179, 21-35.
    • (1984) J. Mol. Biol. , vol.179 , pp. 21-35
    • Powell, D.J.1    Friedman, J.M.2    Oulette, A.J.3    Krauter, K.S.4    Darnell Jr., J.E.5
  • 50
    • 0023634360 scopus 로고
    • Continuous high-dose factor VIII for the induction of immune tolerance in haemophilia a patients with high responder state: A description of eleven patients treated
    • SCHEIBEL, E., INGERSLEV, J., DALSGAARD-NIELSEN, J., STENBJERG, S., and KNUDSEN, J.B. (1987). Continuous high-dose factor VIII for the induction of immune tolerance in haemophilia A patients with high responder state: a description of eleven patients treated. Thromb. Haemost. 58, 1049-1052.
    • (1987) Thromb. Haemost. , vol.58 , pp. 1049-1052
    • Scheibel, E.1    Ingerslev, J.2    Dalsgaard-Nielsen, J.3    Stenbjerg, S.4    Knudsen, J.B.5
  • 52
    • 0025487393 scopus 로고
    • Evaluation of the transfer and expression in mice of an enzyme-encoding gene using a human adenovirus vector
    • STRATFORD-PERRICAUDET, L.D., LEVRERO, M., CHASSE, J., PERRICAUDET, M., and BRIAND, P. (1990). Evaluation of the transfer and expression in mice of an enzyme-encoding gene using a human adenovirus vector. Hum. Gene Ther. 1, 241-256.
    • (1990) Hum. Gene Ther. , vol.1 , pp. 241-256
    • Stratford-Perricaudet, L.D.1    Levrero, M.2    Chasse, J.3    Perricaudet, M.4    Briand, P.5
  • 54
    • 0026864920 scopus 로고
    • High level expression of human apolipoprotein A-1 in transgenic rats raises total serum high density lipoprotein cholesterol and lowers rat apolipoprotein A-1
    • SWANSON, M.E., HUGHES, T.E., ST. DENNY, I., FRANCE, D.S., PATERNITI, J.R., TAPPARELLI, C., GFELLER, P., and BURKI, K. (1992). High level expression of human apolipoprotein A-1 in transgenic rats raises total serum high density lipoprotein cholesterol and lowers rat apolipoprotein A-1. Transgenic Res. 1, 142-147.
    • (1992) Transgenic Res. , vol.1 , pp. 142-147
    • Swanson, M.E.1    Hughes, T.E.2    St. Denny, I.3    France, D.S.4    Paterniti, J.R.5    Tapparelli, C.6    Gfeller, P.7    Burki, K.8
  • 55
    • 0020425067 scopus 로고
    • Adenovirus VAI RNA is required for efficient translation of viral mRNAs at late times after infection
    • THIMMAPPAYA, B., WEINBERGER, C., SCHNEIDER, R.J., and SHENK, T. (1982). Adenovirus VAI RNA is required for efficient translation of viral mRNAs at late times after infection. Cell 3, 543-551.
    • (1982) Cell , vol.3 , pp. 543-551
    • Thimmappaya, B.1    Weinberger, C.2    Schneider, R.J.3    Shenk, T.4
  • 58
    • 0022760260 scopus 로고
    • A large region (≈95 kDa) of human factor VIII is dispensable for in vitro procoagulant activity
    • TOOLE, J.J., PITTMAN, D.D., ORR, E.C., MURTHA, P., WASLEY, L.C., and KAUFMAN, R.J. (1986). A large region (≈95 kDa) of human factor VIII is dispensable for in vitro procoagulant activity. Proc. Natl. Acad. Sci. USA 83, 5939-5942.
    • (1986) Proc. Natl. Acad. Sci. USA , vol.83 , pp. 5939-5942
    • Toole, J.J.1    Pittman, D.D.2    Orr, E.C.3    Murtha, P.4    Wasley, L.C.5    Kaufman, R.J.6
  • 59
    • 0003378938 scopus 로고
    • Factor VIII and factor V: Biochemistry and pathophysiology
    • Curr. Stud. Hematol. Blood. Transf. A. Albertini, C.L. Lenfant, P.M. Mannucci, and J.J. Sixmaeds, eds. (Karger, Base)
    • VEHAR, G.A., LAWN, R.M., TUDDENHAM, E.G.D., and WOOD, W.I. (1991). Factor VIII and factor V: Biochemistry and pathophysiology. In Biotechnology of plasma proteins. Curr. Stud. Hematol. Blood. Transf. A. Albertini, C.L. Lenfant, P.M. Mannucci, and J.J. Sixmaeds, eds. (Karger, Base) pp. 2155-2170.
    • (1991) Biotechnology of Plasma Proteins , pp. 2155-2170
    • Vehar, G.A.1    Lawn, R.M.2    Tuddenham, E.G.D.3    Wood, W.I.4
  • 61
    • 0027196615 scopus 로고
    • An approach for treating the hepatobiliary disease of cystic fibrosis by somatic gene transfer
    • YANG, Y., RAPER, S.E., COHN, J.A., ENGELHARDT, J.F., and WILSON, J.M. (1993). An approach for treating the hepatobiliary disease of cystic fibrosis by somatic gene transfer. Proc. Natl. Acad. Sci. USA 90, 4601-4605.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 4601-4605
    • Yang, Y.1    Raper, S.E.2    Cohn, J.A.3    Engelhardt, J.F.4    Wilson, J.M.5
  • 63
    • 0027377523 scopus 로고
    • Adenovirus-mediated gene transfer transiently corrects the chloride transport defect in nasal epithelia of patients with cystic fibrosis
    • ZABNER, J., COUTURE, L.A., GREGORY, R.J., GRAHAM, S.M., SMITH, A.E., and WELSH, M.J. (1993). Adenovirus-mediated gene transfer transiently corrects the chloride transport defect in nasal epithelia of patients with cystic fibrosis. Cell 75, 207-216.
    • (1993) Cell , vol.75 , pp. 207-216
    • Zabner, J.1    Couture, L.A.2    Gregory, R.J.3    Graham, S.M.4    Smith, A.E.5    Welsh, M.J.6
  • 65
    • 0028290674 scopus 로고
    • In vivo production of human factor VIII in mice after intrasplenic implantation of primary fibroblasts transfected by receptor-mediated, adenovirus-augmented gene delivery
    • ZATLOUKAL, K., COTTEN, M., BERGER, M., SCHMIDT, W., WAGNER, E., and BIRNSTIEL, M.L. (1994). In vivo production of human factor VIII in mice after intrasplenic implantation of primary fibroblasts transfected by receptor-mediated, adenovirus-augmented gene delivery. Proc. Natl. Acad. Sci. USA 91, 5148-5152.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 5148-5152
    • Zatloukal, K.1    Cotten, M.2    Berger, M.3    Schmidt, W.4    Wagner, E.5    Birnstiel, M.L.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.