Chimeric vesicular monoamine transporters identify structural domains that influence substrate affinity and sensitivity to tetrabenazine

Journal of Biological Chemistry

Volumn 271, Issue 6, 1996, Pages 2979-2986

  Peter, Doris ^a   Vu, Trung ^a   Edwards, Robert H ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARRIER PROTEIN; CHIMERIC PROTEIN; HISTAMINE; MONOAMINE; SEROTONIN; TETRABENAZINE;

ANIMAL CELL; ARTICLE; MEMBRANE VESICLE; MONKEY; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY;

ANIMALS; CELL MEMBRANE; CERCOPITHECUS AETHIOPS; HISTAMINE; KINETICS; MEMBRANE GLYCOPROTEINS; MEMBRANE TRANSPORT PROTEINS; MUTAGENESIS, SITE-DIRECTED; NEUROPEPTIDES; NEUROTRANSMITTER AGENTS; POINT MUTATION; PROTEIN STRUCTURE, SECONDARY; RATS; RECOMBINANT FUSION PROTEINS; RESERPINE; SEROTONIN; SUBSTRATE SPECIFICITY; TETRABENAZINE; TRANSFECTION; VESICULAR BIOGENIC AMINE TRANSPORT PROTEINS; VESICULAR MONOAMINE TRANSPORT PROTEINS;

EID: 0030038198     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.271.6.2979     Document Type: Article

References (28)

1. Sudhof, T. C., and Jahn, R. (1991) Neuron 6, 665-677
2. Edwards, R. H. (1992) Curr. Opin Neurobiol. 2, 586-594
3. Schuldiner, S., Shirvan, A., and Linial, M (1995) Physiol. Rev. 75, 369-392
4. Rudnick, G (1986) Annu. Rev Physiol. 48, 403-413
5. Forgac, M (1089) Physiol. Rev 69, 765-796
6. Knoth, J., Zallakian, M , and Njus, D. (1981) Biochemistry 20, 6625-6629
7. Kanner, B I., and Schuldiner, S (1987) CRC Crit Rev. Biochem. 22, 1-38
8. Johnson, R. G. (1988) Physiol. Rev. 68, 232-307
9. Daniels, A. J., and Reinhard, J F (1988) J. Biol. Chem. 263, 5034-5036
10. Scherman, D , Darchen, F., Desnos, C., and Henry, J. P. (1988) Eur. J. Pharmacol 146, 359-360
11. Liu, Y., Roghani, A , and Edwards, R. H. (1992) Proc. Natl. Acad. Sci. U. S. A. 89, 9074-9078
12. Liu, Y., Peter, D., Roghani, A., Schuldiner, S., Prive, G. G., Eisenberg, D., Brecha, N., and Edwards, R. H. (1992) Cell 70, 539-551
13. Monyama, Y., Amakatsu, K., and Futai, M (1993) Arch. Biochem Biophys. 305, 271-277
14. Weaver, J. H., and Deupree, J. D. (1982) Eur. J. Pharmacol 80, 437-438
15. Scherman, D , and Henry, J P (1984) Mol Pharmacol. 25, 113-122
16. Darchen, F., Scherman, D., and Henry, J. P. (1989) Biochemistry 28, 1692-1697
17. Enrikson, J. D , Eiden, L E , and Hoffman, B. J. (1992) Proc. Natl. Acad. Sci. U. S. A. 89, 10993-10997
18. Peter, D , Liu, Y , Sternini, C , de Giorgio, R., Brecha, N., and Edwards, R. H. (1995) J. Neurosci. 15, 6179-6188
19. Peter, D., Jimenez, J , Liu, Y., Kim, J., and Edwards, R H (1994) J. Biol. Chem. 269, 7231-7237
20. Moore, K. R., and Blakely, R D. (1994) BioTechniques 17, 130-137
21. Buck, K. J, and Amara, S. G. (1994) Proc. Natl Acad Sci U S.A. 91, 12584-12588
22. Sanger, F , Nicklen, S , and Coulson, A. (1977) Proc. Natl. Acad Sci. U S. A. 74, 5463-5467
23. Merickel, A., and Edwards, R H (1990) Neuropharmacology 34, 1543-1547
24. Barker, E. L., Kimmel, H L , and Blakely, R. D. (1994) Mol. Pharmacol. 46, 799-807
25. Giros, B., Wang, Y M., Suter, S., McLeskey, S. B., Pifl, C., and Caron, M. G. (1994) J. Biol Chem 269, 15985-15988
26. Fukami, M H., Holmsen, H., and Ugurbil, K. (1984) Biochem. Pharmacol. 33, 3869-3874
27. Menckel, A, Rosandich, P., Peter, D., and Edwards, R. H. (1995) J. Biol. Chem. 270, 25798-25804
28. Schuldiner, S., Liu, Y., and Edwards, R H. (1993) J Biol. Chem. 268, 29-34