H+ permeation and pH regulation at a mammalian serotonin transporter

Journal of Neuroscience

Volumn 17, Issue 7, 1997, Pages 2257-2266

  Cao, Yongwei ^a   Mager, Sela ^a   Lester, Henry A ^a  

^a CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

5 HT; protons; serotonin; SERT; sodium; Xenopus oocyte

Indexed keywords

ANIMAL CELL; ARTICLE; BINDING SITE; ION CURRENT; KINETICS; MEMBRANE CURRENT; NONHUMAN; PH; PRIORITY JOURNAL; PROTON TRANSPORT; SEROTONINERGIC SYSTEM; XENOPUS;

EID: 0030898821     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.17-07-02257.1997     Document Type: Article

References (14)

1. Billups B, Attwell D (1996) Modulation of non-vesicular glutamate release by pH. Nature 379:171-174.
2. Cammack JN, Schwartz EA (1996) Channel behavior in a GABA transporter. Proc Natl Acad Sci USA 93:723-727.
3. Cammack JN, Rakhilin SV, Schwartz EA (1994) A GABA transporter operates asymmetrically and with variable stoichiometry. Neuron 13:949-960.
4. Csiba L, Paschen W, Hossmann K-A (1983) A topographic quantitative method for measuring brain tissue pH under physiological and pathophysiological conditions. Brain Res 289:334-337.
5. Deamer DW, Nichols JW (1989) Proton flux mechanisms in model and biological membranes. J Membr Biol 107:91-103.
6. Nagle JF, Morowitz HJ (1978) Molecular mechanisms for proton transport in membranes. Proc Natl Acad Sci USA 75:298-302.
7. + translocation along the single-file water chain in the gramicidin A channel. Biophys J 71:19-39.
8. Quick MW, Lester HA (1994) Methods for expression of excitability proteins in Xenopus oocytes. In: Ion channels of excitable cells (Narahashi T, ed), pp 261-279. San Diego: Academic.
9. Robinson RA, Stokes RH (1965) Electrolyte solutions; the measurement and interpretation of conductance, chemical potential, and diffusion in solutions of simple electrolytes. London: Butterworths.
10. Rudnick G, Clark J (1993) From synapse to vesicle: the reuptake and storage of biogenic amine neurotransmitters. Biochim Biophys Acta 1144:249-263.
11. Sasaki S, Ishibashi K, Nagai T, Marumo F (1992) Regulation mechanisms of intracellular pH of Xenopus laevis oocyte. Biochim Biophys Acta 1137:45-51.
12. Vandenberg RJ, Arriza JL, Amara SG, Kavanaugh MP (1995) Constitutive ion fluxes and substrate binding domains of human glutamate transporters. J Biol Chem 270:17668-17671.
13. B receptors. Mol Brain Res 16:204-210.
14. Zeidel ML, Nielsen S, Smoth BL, Ambudkar SV, Maunsbach AB, Agre P (1994) Ultrastructure, phamacologic inhibition, and transport selectivity of aquaporin channel-forming integral protein in proteoliposomes. Biochemistry 33:1606-1615.