SAP30, a novel protein conserved between human and yeast, is a component of a histone deacetylase complex

Molecular Cell

Volumn 1, Issue 7, 1998, Pages 1021-1031

  Zhang, Yi ^a   Sun, Zu Wen ^a   Iratni, Rabah ^a   Erdjument Bromage, Hediye ^b   Tempst, Paul ^b   Hampsey, Michael ^a   Reinberg, Danny ^a  

^a UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY   (United States)

^b MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FUNGAL PROTEIN; HISTONE DEACETYLASE; PROTEIN; REPRESSOR PROTEIN; RPD3 PROTEIN, S CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEIN; SAP30 PROTEIN, HUMAN; SAP30 PROTEIN, S CEREVISIAE; SIN3 PROTEIN, S CEREVISIAE; TRANSCRIPTION FACTOR;

AMINO ACID SEQUENCE; ARTICLE; CHEMISTRY; ENZYMOLOGY; GENETICS; HELA CELL; HUMAN; METABOLISM; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; PHYSIOLOGY; SACCHAROMYCES CEREVISIAE; SEQUENCE HOMOLOGY;

AMINO ACID SEQUENCE; CONSERVED SEQUENCE; FUNGAL PROTEINS; HELA CELLS; HISTONE DEACETYLASES; HUMANS; MOLECULAR SEQUENCE DATA; PROTEINS; REPRESSOR PROTEINS; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; TRANSCRIPTION FACTORS;

EID: 0032088533     PISSN: 10972765     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1097-2765(00)80102-1     Document Type: Article

References (66)

1. Alland, L., Muhle, R., Hou, H., Jr., Potes, J., Chin, L., Schreiber-Agus, N., and DePinho, R.A. (1997). Role for N-CoR and histone deacetylase in Sin3-mediated transcriptional repression. Nature 387, 49-55.
2. Allfrey, V., Faulkner, R.M., and Mirsky, A.E. (1964). Acetylation and methylation of histones and their possible role in the regulation of RNA synthesis. Proc. Natl. Acad. Sci. USA 51, 786-794.
3. Aparicio, O.M., Billington, B.L., and Gottschling, D.E. (1991). Modifiers of position effect are shared between telomeric and silent mating-type loci in S. cerevisiae. Cell 66, 1279-1287.
4. Ausio, J., and van Holde, K.E. (1986). Histone hyperacetylation: its effects on nucleosome conformation and stability. Biochemistry 25, 1421-1428.
5. Braunstein, M., Rose, A.B., Holmes, S.G., Allis, C.D., and Broach, J.R. (1993). Transcriptional silencing in yeast is associated with reduced nucleosome acetylation. Genes Dev. 7, 592-604.
6. Braunstein, M., Sobel, R.E., Allis, C.D., Turner, B.M., and Broach, J.R. (1996). Efficient transcriptional silencing in Saccharomyces cerevisiae requires a heterochromatin histone acetylation pattern. Mol. Cell. Biol. 16, 4349-4356.
7. Brehm, A., Miska, E.A., McCance, D.J., Reid, J.L., Bannister, A.J., and Kouzarides, T. (1998). Retinoblastoma protein recruits histone deacetylase to repress transcription. Nature 391, 601-605.
8. Brownell, J.E.,and Allis, C.D. (1996). Special HATs for special occasions: linking histone acetylation to chromatin assembly and gene activation. Curr. Opin. Genet. Dev. 6, 176-184.
9. Cairns, B.R. (1998).Chromatin remodeling machines:similar motors, ulterior motives. Trends Biochem. Sci. 23, 20-25.
10. Carmen, A.A., Rundlett, S.E., and Grunstein, M. (1996). HDA1 and HDA3 are components of a yeast histone deacetylase (HDA) complex. J. Biol. Chem. 271, 15837-15844.
11. De Rubertis, F., Kadosh, D., Henchoz, S., Pauli, D., Reuter, G., Struhl, K., and Spierer, P. (1996). The histone deacetylase RPD3 counteracts genomic silencing in Drosophila and yeast. Nature 384, 589-591.
12. Edmondson, D.G., Smith, M.M., and Roth, S.Y. (1996). Repression domain of the yeast global repressor Tup1 interacts directly with histones H3 and H4. Genes Dev. 10, 1247-1259.
13. Ekwall, K., Olsson, T., Turner, B.M., Cranston, G., and Allshire, R.C. (1997). Transient inhibition of histonedeacetylation alters the structural and functional imprint at fission yeast centromeres. Cell 91, 1021-1032.
14. Gottschling, D.E., Aparicio, O.M., Billington, B.L., and Zakian, V.A. (1990). Position effect at S. cerevisiae telomeres: reversible repression of pol II transcription. Cell 63, 751-762.
15. Grunstein, M. (1997). Histone acetylation in chromatin structure and transcription. Nature 389, 349-352.
16. Gu, W., and Roeder, R.G. (1997). Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain. Cell 90, 595-606.
17. Harlow, E., and Lane, D. (1988). Antibodies: A Laboratory Manual (Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press).
18. Hassig, C.A., Fleischer, T.C., Billin, A.N., Schreiber, S.L., and Ayer, D.E. (1997). Histone deacetylase activity is required for full transcriptional repression by mSin3A. Cell 89, 431-347.
19. Hebbes, T.R., Thorne, A.W., and Crane-Robinson, C. (1988). A direct link between core histone acetylation and transcriptionally active chromatin. EMBO J. 7, 1395-1402.
20. Hecht, A., Laroche, T., Strahl-Bolsinger, S., Gasser, S.M., and Grunstein, M. (1995). Histone H3 and H4 N termini interact with SIR3 and SIR4 proteins: a molecular model for the formation of heterochromatin in yeast. Cell 80, 583-592.
21. Heinzel, T., Lavinsky, B.M., Mullen, T.-M., Söderström, M., Laherty, C.D., Torchia, J., Yang, W.-M., Brard, G., Ngo, S.D., Davie, J.R., et al. (1997). A complex containing N-CoR, mSin3 and histone deacetylase mediates transcription repression. Nature 387, 43-48.
22. Hendzel, M.J., Delcuve, G.P., and Davie, J.R. (1991). Histone deacetylase is a component of the internal nuclear matrix. J. Biol. Chem. 266, 21936-21942.
23. Hong, L., Schroth, G.P., Matthews, H.B., Yau, P., and Bradbury, E.M. (1993). Studies of the DNA binding properties of histone H4 amino terminus. Thermal denaturation studies reveal that acetylation markedly reduces the binding constant of the H4 "tail" to DNA. J. Biol. Chem. 268, 305-314.
24. Imhof, A., Yang, X.J., Ogryzko, V.V., Nakatani, Y., Wolffe, A.P., and Ge, H. (1997). Acetylation of general transcription factors by histone acetyltransferases. Curr. Biol. 7, 689-692.
25. Kadonaga, J.T. (1998). Eukaryotic transcription: an interlaced network of transcription factors and chromatin-modifying machines. Cell 92, 307-313.
26. Kadosh, D., and Struhl, K. (1997). Bepression by Ume6 involves recruitment of a complex containing Sin3 corepressor and Rpd3 histone deacetylase to target promoters. Cell 89, 365-371.
27. Kadosh, D., and Struhl, K. (1998). Histone deacetylase activity of Rpd3 is important for transcriptional repression in vivo. Genes Dev. 12, 797-805.
28. Kasten, M.M., Dorland, S., and Stillman, D.J. (1997). A large protein complex containing the yeast SinSp and RpdSp transcriptional regulators. Mol. Cell. Biol. 17, 4852-4858.
29. Kaufman, P.D., Kobayashi, R., and Stillman B. (1997). Ultraviolet radiation sensitivity and reduction of telomeric silencing in Saccharomyces cerevisiae cells lacking chromatin assembly factor-I. Genes Dev. 11, 345-357.
30. Keleher, C.A., Redd, M.J., Schultz, J., Carlson, M., and Johnson, A.D. (1992). Ssn6-Tup1 is a general repressor of transcription in yeast. Cell 68, 709-719.
31. Kingston, R.E., Bunker C.A., and Imbalzano, A.N. (1996). Bepression and activation by multiprotein complexes that alterchromatin structure. Genes Dev. 10, 905-920.
32. Laherty, C.D., Yang, W.-M., Sun, J.-M., Davie, J.R., Seto, E., and Eisenman, R.N. (1997). Histone deacetylases associated with the mSin3 corepressor mediate Mad transcriptional repression. Cell 89, 349-356.
33. Lee, D.Y., Hayes, J.J., Pruss, D., and Wolffe, A.P. (1993). A positive role for histone acetylation in transcription factor access to nucleosomal DNA. Cell 72, 73-84.
34. Lennox, R.W., and Cohen, L.H. (1989). Analysis of histone subtypes and their modified forms by polyacrylamide gel electrophoresis. Meth. Enzymol. 170, 532-549.
35. Li, Y., Bjorklund, S., Jiang, Y.W., Kim, Y.J., Lane, W.S., Stillman, D.J., and Kornberg, R.D. (1995). Yeast global transcriptional regulators Sin4 and Rgr1 are components of mediator complex RNApolymerase II holoenzyme. Proc. Natl. Acad. Sci. USA 92, 10864-10868.
36. Luger, K., Mader, A.W., Richmond, R.K., Sargent, D.F., and Richmond, T.J. (1997). Crystal structure of the nucleosome core particle at 2.8 Àresolution. Nature 389, 251-260.
37. Luo, R.X., Postigo, A.A., and Dean, D.C. (1998). Rb interacts with histone deacetylase to repress transcription. Cell 92, 463-473.
38. Magnaghi-Jaulin, L., Groisman, R., Naguibneva, I., Robin, P., Lorain, S., Le Villain, J.P., Troalen, F., Trouche, D., and Harel-Bellan, A. (1998). Retinoblastoma protein represses transcription by recruiting a histone deacetylase. Nature 391, 601-605.
39. Martinez-Balbas, M.A., Tsukiyama.T., Gdula, D., and Wu, C. (1998). Drosophila NURF-55, a WD repeat protein involved in histone me-tabolism. Proc. Natl. Acad. Sci. USA 95, 132-137.
40. Nagy, L., Kao, H.-Y., Chakravarti, D., Lin, R.J., Hassig, C.A., Ayer, D.E., Schreiber, S.L., and Evans, R.M. (1997). Nuclear receptor repression mediated by a complex containing SMRT, mSin3A, and histone deacetylase. Cell 89, 373-380.
41. Orphanides, G., LeRoy, G., Chang, C.-H., Luse, D., and Reinberg, D. (1998). FACT, a factor that facilitates transcript elongation through nucleosomes. Cell 92, 105-116.
42. Paranjape, S.M., Kamakaka, R.T., and Kadonaga, J.T. (1994). Role of chromatin structure in the regulation of transcription by RNA polymerase II. Annu. Rev. Biochem. 63, 265-297.
43. Parthun, M.R., Widom, J., and Gottschling, D.E. (1996). The major cytoplasmic histone acetyltransferase in yeast: links to chromatin replication and histone metabolism. Cell 87, 85-94.
44. Pazin, M.J., and Kadonaga, J.T. (1997). What's up and down with histone deacetylation and transcription? Cell 89, 325-328.
45. Qian, Y.-W., and Lee, E.Y.-H.P. (1995). Dual retinoblastoma-binding proteins with properties related to a negative regulator of Ras in yeast. J. Biol. Chem. 270, 25507-25513.
46. Qian, Y.-W., Wang, Y.-C.J., Hollingsworth, R.E.J., Jones, D., Ling, N., and Lee, E.Y.-H.P. (1993). A retinoblastoma-binding protein related to a negative regulator of Ras in yeast. Nature 364, 648-652.
47. Rundlett, S.E., Carmen, A.A., Kobayashi, R., Bavykin, S., Turner, B.M., and Grunstein, M. (1996). HDA1 and RPD3 are members of distinct yeast histone deacetylase complexes that regulate silencing and transcription. Proc. Natl. Acad. Sci. USA 93, 14503-14508.
48. Sheridan, P.L., Mayall, T.P., Verdin, E., and Jones, K.A. (1997). Histone acetyltransferases regulate HIV-1 enhancer activity in vitro. Genes Dev. 11, 3327-3340.
49. Sommer, A., Hilfenhaus, S., Menkel, A., Kremmer, E., Seiser, C., Loidl, P., and Luscher, B. (1997). Cell growth inhibition by the Mad/ Max complex through recruitment of histone deacetylase activity. Curr. Biol. 7, 357-365.
50. Struhl, K. (1998). Histone acetylation and transcriptional regulatory mechanisms. Genes Dev. 12, 599-606.
51. Taunton, J., Hassig, C.A., and Schreiber, S.L. (1996). A mammalian histone deacetylase related to the yeast transcriptional regulator RPDSp. Science 272, 408-411.
52. Tsukiyama, T., and Wu, C. (1995). Purification and properties of an ATP-dependent nucleosome remodeling factor. Cell 83, 1011-1020.
53. Turner, B.M., Birley, A.J., and Lavender, J. (1992). Histone H4 isoforms acetylated at specific lysine residues define individual chromosomes and chromatin domains in Drosophila polytene nuclei. Cell 69, 375-384.
54. Tyler, J.K., Bulger, M., Kamakaka, R.T., Kobayashi, R., and Kadonaga, J.T. (1996). The p55 subunit of Drosophila chromatin assembly factor 1 is homologous to a histone deacetylase-associated protein. Mol. Cell. Biol. 16, 6149-6159.
55. Van Holde, K.E. (1989). Chromatin, A. Rich, ed. (Berlin, Germany: Springer-Verlag).
56. Van Lint, C., Emiliani, S., and Verdin, E. (1996). The expression of a small fraction of cellular genes is changed in response to histone hyperacetylation. Gene Expr. 5, 245-253.
57. Vannier, D., Balderes, D., and Shore, D. (1996). Evidence that the transcriptional regulators SIN3 and RPD3, and a novel gene (SDS3) with similar functions, are involved in transcriptional silencing in S. cerevisiae. Genetics 144, 1343-1353.
58. Verreault, A., Kaufman, P.D., Kobayashi, R., and Stillman, B. (1996). Nucleosome assembly by a complex of CAF-1 and acetylated histones H3/H4. Cell 87, 95-104.
59. Verreault, A., Kaufman, P.D., Kobayashi, R., and Stillman, B. (1997). Nucleosomal DNA regulates the core-histone-binding subunit of the human hat1 acetyltransferase. Curr. Biol. 8, 96-108.
60. Vettese-Dadey, M., Grant, P.A., Hebbes, T.R., Crane-Robinson, C., Allis, C.D., and Workman, J.L. (1996). Acetylation of histone H4 plays a primary role in enhancing transcription factor binding to nucleosomal DNA in vitro. EMBO J. 15, 2508-2518.
61. Vidai, M., and Gaber, R.F. (1991). RPD3 encodes a second factor required to achieve maximum positive and negative transcriptional states in Saccharomyces cevisiae. Mol. Cell. Biol. 11, 6317-6327.
62. Vidai, M., Strich, R., Esposito, R.E., and Gaber, R.F. (1991). RPD1 (SIN3/UME4) is required for maximal activation and repression of diverse yeast genes. Mol. Cell. Biol. 11, 6306-6316.
63. Wade, P.A., Pruss, D., and Wolffe, A.P. (1997). Histone acetylation: chromatin in action. Trends Biochem Sci. 22, 128-132.
64. Wu, C. (1997). Chromatin remodeling and the control of gene expression. J. Biol. Chem. 272, 28171-28174.
65. Yang, W.-M., Inouye, C., Zeng, Y.Y., Bearss, D.,and Seto, E. (1996). Transcriptional repression by YY1 is mediated by interaction with a mammalian homolog of the yeast global regulator RPD3. Proc. Natl. Acad. Sci. USA 93, 12845-12850.
66. Zhang, Y., Iratni, R., Erdjument-Bromage, H., Tempst, P., and Reinberg, D. (1997). Histone deacetylases and SAP18, a novel polypeptide, are components of a human Sin3 complex. Cell 89, 357-364.