-
1
-
-
0010596568
-
Essentials of signal transduction
-
V. DeVita, S. Hellman, Rosenberg S. edn 5 Philadelphia, PA: Lippincott-Raven Press
-
Heimbrook DC, Oliff A, Gibbs JB. Essentials of signal transduction. DeVita V, Hellman S, Rosenberg S. edn 5 Cancer Principles and Practice of Oncology. 1997;35-43 Lippincott-Raven Press, Philadelphia, PA.
-
(1997)
Cancer Principles and Practice of Oncology
, pp. 35-43
-
-
Heimbrook, D.C.1
Oliff, A.2
Gibbs, J.B.3
-
3
-
-
0024376173
-
Ras oncogenes in human cancer: A review
-
Bos JL. Ras oncogenes in human cancer: a review. Cancer Res. 49:1989;4682-4689.
-
(1989)
Cancer Res
, vol.49
, pp. 4682-4689
-
-
Bos, J.L.1
-
4
-
-
0028331587
-
Farnesyl transferase inhibitors: Ras research yields a potential cancer therapeutic
-
Kohl NE, Oliff A, Gibbs JB. Farnesyl transferase inhibitors: Ras research yields a potential cancer therapeutic. Cell. 77:1994;175-178.
-
(1994)
Cell
, vol.77
, pp. 175-178
-
-
Kohl, N.E.1
Oliff, A.2
Gibbs, J.B.3
-
5
-
-
0027323459
-
Benzodiazepine peptidomimetics: Potent inhibitors of Ras farnesylation in animal cells
-
James GL, Goldstein JL, Brown MS, Rawson TE, Somers TC, McDowell RS, Crowley CW, Lucas BK, Levinson AD, Marsters JC Jr. Benzodiazepine peptidomimetics: potent inhibitors of Ras farnesylation in animal cells. Science. 260:1993;1937-1942.
-
(1993)
Science
, vol.260
, pp. 1937-1942
-
-
James, G.L.1
Goldstein, J.L.2
Brown, M.S.3
Rawson, T.E.4
Somers, T.C.5
McDowell, R.S.6
Crowley, C.W.7
Lucas, B.K.8
Levinson, A.D.9
Marsters J.C., Jr.10
-
6
-
-
0027248872
-
Selective inhibition of ras-dependent transformation by a farnesyltransferase inhibitor
-
Kohl NE, Mosser SD, deSolms SJ, Giuliani EA, Pompliano DL, Graham SL, Smith RL, Scolnick EM, Oliff A, Gibbs JB. Selective inhibition of ras-dependent transformation by a farnesyltransferase inhibitor. Science. 260:1993;1934-1937.
-
(1993)
Science
, vol.260
, pp. 1934-1937
-
-
Kohl, N.E.1
Mosser, S.D.2
Desolms, S.J.3
Giuliani, E.A.4
Pompliano, D.L.5
Graham, S.L.6
Smith, R.L.7
Scolnick, E.M.8
Oliff, A.9
Gibbs, J.B.10
-
7
-
-
0029150669
-
Inhibition of farnesyltransferase induces regression of mammary and salivary carcinomas in ras transgenic mice
-
Kohl NE, Omer CA, Conner MW, Anthony NJ, Davide JP, deSolms J, Giuliani EA, Gomez RP, Graham SL, Hamilton K, et al. Inhibition of farnesyltransferase induces regression of mammary and salivary carcinomas in ras transgenic mice. Nat Med. 1:1995;792-797.
-
(1995)
Nat Med
, vol.1
, pp. 792-797
-
-
Kohl, N.E.1
Omer, C.A.2
Conner, M.W.3
Anthony, N.J.4
Davide, J.P.5
Desolms, J.6
Giuliani, E.A.7
Gomez, R.P.8
Graham, S.L.9
Hamilton, K.10
-
8
-
-
0028958919
-
Polylysine and CVIM sequences of K-RasB dictate specificity of prenylation and confer resistance to benzodiazepine peptidomimetic in vitro
-
James GL, Goldstein JL, Brown MS. Polylysine and CVIM sequences of K-RasB dictate specificity of prenylation and confer resistance to benzodiazepine peptidomimetic in vitro. J Biol Chem. 270:1995;6221-6226.
-
(1995)
J Biol Chem
, vol.270
, pp. 6221-6226
-
-
James, G.L.1
Goldstein, J.L.2
Brown, M.S.3
-
9
-
-
0030923192
-
K- And N-Ras are geranylgeranylated in cells treated with farnesyl protein transferase inhibitors
-
of special interest. A quantitative examination of the prenylation patterns of Ras proteins in intact cells. The study clearly shows that geranylgeranylation of N- and K-Ras is dramatically enhanced if the farnesylation pathway is inhibited.
-
Whyte DB, Kirschmeier P, Hockenberry TN, Nunez-Oliva I, James L. K- and N-Ras are geranylgeranylated in cells treated with farnesyl protein transferase inhibitors. of special interest J Biol Chem. 272:1997;14459-14464 A quantitative examination of the prenylation patterns of Ras proteins in intact cells. The study clearly shows that geranylgeranylation of N- and K-Ras is dramatically enhanced if the farnesylation pathway is inhibited.
-
(1997)
J Biol Chem
, vol.272
, pp. 14459-14464
-
-
Whyte, D.B.1
Kirschmeier, P.2
Hockenberry, T.N.3
Nunez-Oliva, I.4
James, L.5
-
10
-
-
0030968859
-
Direct demonstration of geranylgeranylation and farnesylation of Ki-Ras in vivo
-
Rowell CA, Kowalczyk JJ, Lewis MD, Garcia AM. Direct demonstration of geranylgeranylation and farnesylation of Ki-Ras in vivo. J Biol Chem. 272:1997;14093-14097.
-
(1997)
J Biol Chem
, vol.272
, pp. 14093-14097
-
-
Rowell, C.A.1
Kowalczyk, J.J.2
Lewis, M.D.3
Garcia, A.M.4
-
11
-
-
0026659959
-
Specific isoprenoid modification is required for function of normal, but not oncogenic, Ras protein
-
Cox AD, Hisaka MM, Buss JE, Der CJ. Specific isoprenoid modification is required for function of normal, but not oncogenic, Ras protein. Mol Cell Biol. 12:1992;2606-2615.
-
(1992)
Mol Cell Biol
, vol.12
, pp. 2606-2615
-
-
Cox, A.D.1
Hisaka, M.M.2
Buss, J.E.3
Der, C.J.4
-
12
-
-
0030943198
-
Characterization of Ha-ras, N-ras, Ki-Ras4A, and Ki-Ras4B as in vitro substrates for farnesyl protein transferase and geranylgeranyl protein transferase type I
-
Zhang FL, Kirschmeier P, Carr D, James L, Bond RW, Wang L, Patton R, Windsor WT, Syto R, Zhang R, et al. Characterization of Ha-ras, N-ras, Ki-Ras4A, and Ki-Ras4B as in vitro substrates for farnesyl protein transferase and geranylgeranyl protein transferase type I. J Biol Chem. 272:1997;10232-10239.
-
(1997)
J Biol Chem
, vol.272
, pp. 10232-10239
-
-
Zhang, F.L.1
Kirschmeier, P.2
Carr, D.3
James, L.4
Bond, R.W.5
Wang, L.6
Patton, R.7
Windsor, W.T.8
Syto, R.9
Zhang, R.10
-
13
-
-
0030909826
-
Crystal structure of protein farnesyltransferase at 2.25 Å resolution
-
of special interest. Resolution of the crystal structure of FTase at 2.25 Å reveals the zinc binding site at the juncture of two clefts that appear to bind the reaction substrates.
-
Park HW, Boduluri SR, Moomaw JF, Casey PJ, Beese LS. Crystal structure of protein farnesyltransferase at 2.25 Å resolution. of special interest Science. 275:1997;1800-1804 Resolution of the crystal structure of FTase at 2.25 Å reveals the zinc binding site at the juncture of two clefts that appear to bind the reaction substrates.
-
(1997)
Science
, vol.275
, pp. 1800-1804
-
-
Park, H.W.1
Boduluri, S.R.2
Moomaw, J.F.3
Casey, P.J.4
Beese, L.S.5
-
14
-
-
0026747866
-
Isoprenoid addition to Ras protein is the critical modification for its membrane association and transforming activity
-
Kato K, Cox AD, Hisaka MM, Graham SM, Buss JE, Der CJ. Isoprenoid addition to Ras protein is the critical modification for its membrane association and transforming activity. Proc Natl Acad Sci USA. 89:1992;6403-6407.
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 6403-6407
-
-
Kato, K.1
Cox, A.D.2
Hisaka, M.M.3
Graham, S.M.4
Buss, J.E.5
Der, C.J.6
-
15
-
-
0030909336
-
Modulation of Ras and a-factor function by carboxyl-terminal proteolysis
-
of special interest. The RCE1 and AFC1 genes encodes proteases which appear to be responsible for processing of prenylated proteins in yeast. Inactivation of RCE1 causes defects in Ras localization and suppresses Ras activity.
-
Boyartchuk VL, Ashby MN, Rine J. Modulation of Ras and a-factor function by carboxyl-terminal proteolysis. of special interest Science. 275:1997;1796-1800 The RCE1 and AFC1 genes encodes proteases which appear to be responsible for processing of prenylated proteins in yeast. Inactivation of RCE1 causes defects in Ras localization and suppresses Ras activity.
-
(1997)
Science
, vol.275
, pp. 1796-1800
-
-
Boyartchuk, V.L.1
Ashby, M.N.2
Rine, J.3
-
16
-
-
0031584827
-
Inhibition of anchorage-independent growth of ras-transformed cells on polyHEMA surface by antisense oligodeoxynucleotides directed against K-ras
-
Kawada M, Fukazawa H, Mizuno S, Uehara Y. Inhibition of anchorage-independent growth of ras-transformed cells on polyHEMA surface by antisense oligodeoxynucleotides directed against K-ras. Biochem Biophys Res Comm. 231:1997;735-737.
-
(1997)
Biochem Biophys Res Comm
, vol.231
, pp. 735-737
-
-
Kawada, M.1
Fukazawa, H.2
Mizuno, S.3
Uehara, Y.4
-
17
-
-
0030920066
-
Specific hammerhead ribozyme-mediated cleavage of mutant N-ras mRNA in vitro and ex vivo. Oligoribonucleotides as therapeutic agents
-
Scherr M, Grez M, Ganser A, Engels JW. Specific hammerhead ribozyme-mediated cleavage of mutant N-ras mRNA in vitro and ex vivo. Oligoribonucleotides as therapeutic agents. J Biol Chem. 272:1997;14304-14313.
-
(1997)
J Biol Chem
, vol.272
, pp. 14304-14313
-
-
Scherr, M.1
Grez, M.2
Ganser, A.3
Engels, J.W.4
-
18
-
-
0028948382
-
Multiple Ras functions can contribute to mammalian cell transformation
-
White MA, Nicoletter C, Minden A, Polverino A, van Aelst L, Karin M, Wigler MH. Multiple Ras functions can contribute to mammalian cell transformation. Cell. 80:1995;533-541.
-
(1995)
Cell
, vol.80
, pp. 533-541
-
-
White, M.A.1
Nicoletter, C.2
Minden, A.3
Polverino, A.4
Van Aelst, L.5
Karin, M.6
Wigler, M.H.7
-
19
-
-
0029890896
-
Oncogenic Ras activation of Raf/mitogen-activated protein kinase-independent pathways is sufficient to cause tumorigenic transformation
-
Khosravi-Far R, White MA, Westwick JK, Solski PA, Chrzanowska-Wodnicka M, van Aelst L, Wigler MH, Der CJ. Oncogenic Ras activation of Raf/mitogen-activated protein kinase-independent pathways is sufficient to cause tumorigenic transformation. Mol Cell Biol. 16:1996;3923-3933.
-
(1996)
Mol Cell Biol
, vol.16
, pp. 3923-3933
-
-
Khosravi-Far, R.1
White, M.A.2
Westwick, J.K.3
Solski, P.A.4
Chrzanowska-Wodnicka, M.5
Van Aelst, L.6
Wigler, M.H.7
Der, C.J.8
-
21
-
-
0028903247
-
An essential role for Rac in Ras transformation
-
Qiu RG, Chen J, Kirn D, McCormick D, Symons M. An essential role for Rac in Ras transformation. Nature. 374:1995;457-459.
-
(1995)
Nature
, vol.374
, pp. 457-459
-
-
Qiu, R.G.1
Chen, J.2
Kirn, D.3
McCormick, D.4
Symons, M.5
-
22
-
-
0030916369
-
Farnesyltransferase inhibitors after the prenylation and growth-stimulating function of RhoB
-
of outstanding interest. The critical biological targets of farnesyltransferase inhibitors remains an area of controversy in this field. Clearly these drugs are not simply anti-Ras agents. RhoB has always been one of the leading alternate candidates for mediating the effects of FTase inhibitors. This paper now shows that these drugs can specifically antagonize the growth enhancing properties of RhoB.
-
Lebowitz PF, Casey PJ, Prendergast GC, Thissen JA. Farnesyltransferase inhibitors after the prenylation and growth-stimulating function of RhoB. of outstanding interest J Biol Chem. 272:1997;15591-15594 The critical biological targets of farnesyltransferase inhibitors remains an area of controversy in this field. Clearly these drugs are not simply anti-Ras agents. RhoB has always been one of the leading alternate candidates for mediating the effects of FTase inhibitors. This paper now shows that these drugs can specifically antagonize the growth enhancing properties of RhoB.
-
(1997)
J Biol Chem
, vol.272
, pp. 15591-15594
-
-
Lebowitz, P.F.1
Casey, P.J.2
Prendergast, G.C.3
Thissen, J.A.4
-
23
-
-
0030888163
-
The Ras-related protein Rheb is farnesylated and antagonizes Ras signaling and transformation
-
Clark GJ, Kinch MS, Rogers-Graham K, Sebti SM, Hamilton AD, Der CJ. The Ras-related protein Rheb is farnesylated and antagonizes Ras signaling and transformation. J Biol Chem. 272:1997;10608-10615.
-
(1997)
J Biol Chem
, vol.272
, pp. 10608-10615
-
-
Clark, G.J.1
Kinch, M.S.2
Rogers-Graham, K.3
Sebti, S.M.4
Hamilton, A.D.5
Der, C.J.6
-
24
-
-
0029977448
-
Antitumor activity of a phosphorothioate antisense oligodeoxynucleotide targeted against C-raf kinase
-
Monia BP, Johnston JF, Geiger T, Muller M, Fabbro D. Antitumor activity of a phosphorothioate antisense oligodeoxynucleotide targeted against C-raf kinase. Nat Med. 2:1996;675-688.
-
(1996)
Nat Med
, vol.2
, pp. 675-688
-
-
Monia, B.P.1
Johnston, J.F.2
Geiger, T.3
Muller, M.4
Fabbro, D.5
-
25
-
-
0030760355
-
First and second-generation antisense inhibitors targeted to human c-raf kinase: In vitro and in vivo studies
-
Monia BP. First and second-generation antisense inhibitors targeted to human c-raf kinase: in vitro and in vivo studies. Anti-Cancer Drug Design. 12:1997;327-339.
-
(1997)
Anti-Cancer Drug Design
, vol.12
, pp. 327-339
-
-
Monia, B.P.1
-
26
-
-
0029166667
-
PD 098059 is a specific inhibitor of the mitogen-activated protein kinase cascade
-
Alessi DR, Cuenda A, Cohen P, Dudley DT, Saltiel AR. PD 098059 is a specific inhibitor of the mitogen-activated protein kinase cascade. Proc Natl Acad Sci USA. 92:1995;7686-7689.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 7686-7689
-
-
Alessi, D.R.1
Cuenda, A.2
Cohen, P.3
Dudley, D.T.4
Saltiel, A.R.5
-
27
-
-
0030980641
-
Mitogenic signaling mediated by oxidants in Ras-transformed fibroblasts
-
Irani K, Xia Y, Zweier JL, Sollott SJ, Der CJ, Fearon ER, Sundaresan M, Finkel T, Goldschmidt-Clermont PJ. Mitogenic signaling mediated by oxidants in Ras-transformed fibroblasts. Science. 275:1997;1649-1652.
-
(1997)
Science
, vol.275
, pp. 1649-1652
-
-
Irani, K.1
Xia, Y.2
Zweier, J.L.3
Sollott, S.J.4
Der, C.J.5
Fearon, E.R.6
Sundaresan, M.7
Finkel, T.8
Goldschmidt-Clermont, P.J.9
-
28
-
-
0030805703
-
Phosphoinositide 3-kinases: A conserved family of signal transducers
-
of special interest. A concise but thorough review of the PI 3-K field.
-
Vanhaesebroeck B, Leevers SJ, Panayotou G, Waterfield MD. Phosphoinositide 3-kinases: a conserved family of signal transducers. of special interest Trends Biol Sci. 22:1997;267-272 A concise but thorough review of the PI 3-K field.
-
(1997)
Trends Biol Sci
, vol.22
, pp. 267-272
-
-
Vanhaesebroeck, B.1
Leevers, S.J.2
Panayotou, G.3
Waterfield, M.D.4
-
29
-
-
0028074316
-
Phosphatidylinositol-3-OH kinase as a direct target of Ras
-
Rodriguez-Viciana P, Warne PH, Dhand R, Vanhaesebroeck B, Gout I, Fry MJ, Waterfield MD, Downward J. Phosphatidylinositol-3-OH kinase as a direct target of Ras. Nature. 370:1994;527-532.
-
(1994)
Nature
, vol.370
, pp. 527-532
-
-
Rodriguez-Viciana, P.1
Warne, P.H.2
Dhand, R.3
Vanhaesebroeck, B.4
Gout, I.5
Fry, M.J.6
Waterfield, M.D.7
Downward, J.8
-
30
-
-
0030911052
-
Role of phosphoinositide 3-OH kinase in cell transformation and control of the actin cytoskeleton by Ras
-
of special interest. The data presented in this manuscript suggest that PI 3-K is necessary for Ras-induced membrane ruffling, and this pathway is required for efficient Ras-dependent transformation, PI 3-K activity is also shown to be sufficient to cause membrane ruffling, and this activity is mediated by Rac.
-
Rodriguez-Viciana P, Warne PH, Khwaja A, Marte BM, Pappin D, Das P, Waterfield MD, Ridley A, Downward J. Role of phosphoinositide 3-OH kinase in cell transformation and control of the actin cytoskeleton by Ras. of special interest Cell. 89:1997;457-467 The data presented in this manuscript suggest that PI 3-K is necessary for Ras-induced membrane ruffling, and this pathway is required for efficient Ras-dependent transformation, PI 3-K activity is also shown to be sufficient to cause membrane ruffling, and this activity is mediated by Rac.
-
(1997)
Cell
, vol.89
, pp. 457-467
-
-
Rodriguez-Viciana, P.1
Warne, P.H.2
Khwaja, A.3
Marte, B.M.4
Pappin, D.5
Das, P.6
Waterfield, M.D.7
Ridley, A.8
Downward, J.9
-
31
-
-
0029160069
-
Protein Kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction
-
Burgering BM, Coffer PJ. Protein Kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction. Nature. 376:1995;599-602.
-
(1995)
Nature
, vol.376
, pp. 599-602
-
-
Burgering, B.M.1
Coffer, P.J.2
-
32
-
-
10544219605
-
Distinct specificity in the recognition of phosphoinositides by the pleckstrin homology domains of dynamin and Bruton's tyrosine kinase
-
of special interest. These studies demonstrate that different PH domains bind to liposomes containing different phosphoinositides with distinct specificities.
-
Salim K, Bottomley MJ, Querfurth E, Zvelebil MJ, Gout I, Scaife R, Margolis RL, Gigg R, Smith CI, Driscoll PC, et al. Distinct specificity in the recognition of phosphoinositides by the pleckstrin homology domains of dynamin and Bruton's tyrosine kinase. of special interest EMBO J. 15:1996;6241-6250 These studies demonstrate that different PH domains bind to liposomes containing different phosphoinositides with distinct specificities.
-
(1996)
EMBO J
, vol.15
, pp. 6241-6250
-
-
Salim, K.1
Bottomley, M.J.2
Querfurth, E.3
Zvelebil, M.J.4
Gout, I.5
Scaife, R.6
Margolis, R.L.7
Gigg, R.8
Smith, C.I.9
Driscoll, P.C.10
-
33
-
-
0030907987
-
PI3K: Downstream of AKTion blocks apoptosis
-
Franke TF, Kaplan DR, Cantley LC. PI3K: downstream of AKTion blocks apoptosis. Cell. 88:1997;435-437.
-
(1997)
Cell
, vol.88
, pp. 435-437
-
-
Franke, T.F.1
Kaplan, D.R.2
Cantley, L.C.3
-
34
-
-
0031039024
-
Direct regulation of the Akt proto-oncogene product by phosphatidylinositol-3,4-bisphosphate
-
Franke TF, Kaplan DR, Cantley LC, Toker A. Direct regulation of the Akt proto-oncogene product by phosphatidylinositol-3,4-bisphosphate. Science. 275:1997;665-668.
-
(1997)
Science
, vol.275
, pp. 665-668
-
-
Franke, T.F.1
Kaplan, D.R.2
Cantley, L.C.3
Toker, A.4
-
35
-
-
0030799706
-
Dual role of phosphatidylinositol-3,4,5-trisphosphate in the activation of protein kinase B
-
of outstanding interest. See annotation to [37].
-
Stokoe D, Stephens LR, Copeland T, Gaffney PRJ, Reese CB, Painter GF, Holmes AB, McCormick F, Hawkins PT. Dual role of phosphatidylinositol-3,4,5-trisphosphate in the activation of protein kinase B. of outstanding interest Science. 277:1997;567-570 See annotation to [37].
-
(1997)
Science
, vol.277
, pp. 567-570
-
-
Stokoe, D.1
Stephens, L.R.2
Copeland, T.3
Gaffney, P.R.J.4
Reese, C.B.5
Painter, G.F.6
Holmes, A.B.7
McCormick, F.8
Hawkins, P.T.9
-
36
-
-
0031127305
-
Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase B-alpha
-
of outstanding interest. These two references [36,37] characterize the phosphoinositide-activated Akt kinase(s) responsible for phosphorylation of residue Thr308 of Akt.
-
Alessi DR, James SR, Downes CP, Holmes AB, Gaffney PR, Reese CB, Cohen P. Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase B-alpha. of outstanding interest Curr Biol. 7:1997;261-269 These two references [36,37] characterize the phosphoinositide-activated Akt kinase(s) responsible for phosphorylation of residue Thr308 of Akt.
-
(1997)
Curr Biol
, vol.7
, pp. 261-269
-
-
Alessi, D.R.1
James, S.R.2
Downes, C.P.3
Holmes, A.B.4
Gaffney, P.R.5
Reese, C.B.6
Cohen, P.7
-
37
-
-
0030847535
-
Ptdlns(3,4,5)P3 gets its message across
-
Hemmings BA. Ptdlns(3,4,5)P3 gets its message across. Science. 277:1997;534.
-
(1997)
Science
, vol.277
, pp. 534
-
-
Hemmings, B.A.1
-
38
-
-
0030916669
-
The proto-oncogene Bcl-2 and its role in regulating apoptosis
-
Kroemer G. The proto-oncogene Bcl-2 and its role in regulating apoptosis. Nat Med. 3:1997;614-620.
-
(1997)
Nat Med
, vol.3
, pp. 614-620
-
-
Kroemer, G.1
-
39
-
-
1842333237
-
Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt
-
of outstanding interest. The pro-apoptotic activity of the bcl-2 homolog, BAD, is inhibited by phosphorylation at specific serine residues. The data in this manuscript demonstrate that active Akt phosphorylates BAD on these specific serines in response to growth factor stimulation of intact cells.
-
del Peso L, Gonzalez-Garcia M, Page C, Herrera R, Nunez G. Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt. of outstanding interest Science. 278:1997;687-689 The pro-apoptotic activity of the bcl-2 homolog, BAD, is inhibited by phosphorylation at specific serine residues. The data in this manuscript demonstrate that active Akt phosphorylates BAD on these specific serines in response to growth factor stimulation of intact cells.
-
(1997)
Science
, vol.278
, pp. 687-689
-
-
Del Peso, L.1
Gonzalez-Garcia, M.2
Page, C.3
Herrera, R.4
Nunez, G.5
-
40
-
-
0031053586
-
Regulation of neuronal survival by the serine-threonine protein kinase Akt
-
Dudek H, Datta SR, Franke TF, Birnbaum MJ, Yao R, Cooper GM, Segal RA, Kaplan DR, Greenberg ME. Regulation of neuronal survival by the serine-threonine protein kinase Akt. Science. 275:1997;661-665.
-
(1997)
Science
, vol.275
, pp. 661-665
-
-
Dudek, H.1
Datta, S.R.2
Franke, T.F.3
Birnbaum, M.J.4
Yao, R.5
Cooper, G.M.6
Segal, R.A.7
Kaplan, D.R.8
Greenberg, M.E.9
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