Requirement for PP1 phosphatase and 20S cyclosome/APC for the onset of anaphase is lessened by the dosage increase of a novel gene sds23+

EMBO Journal

Volumn 15, Issue 23, 1996, Pages 6629-6640

  Ishii, Kojiro ^a   Kumada, Kazuki ^a   Toda, Takashi ^b   Yanagida, Mitsuhiro ^a  

^a KYOTO UNIVERSITY   (Japan)

^b IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

Author keywords

20S E3 ubiquitin ligase; Cyclosome APC; Mitosis; Proteasome; Schizosaccharomyces pombe

Indexed keywords

ANTIBODY; PHOSPHOPROTEIN PHOSPHATASE; UBIQUITIN;

ANAPHASE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL SHAPE; CELL VIABILITY; CONTROLLED STUDY; CYTOKINESIS; DELETION MUTANT; DEPHOSPHORYLATION; GENE DOSAGE; GENE MUTATION; NONHUMAN; PLASMID; PRIORITY JOURNAL; PROTEIN DEGRADATION; SUPPRESSOR GENE;

SCHIZOSACCHAROMYCES POMBE;

EID: 0029826437     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1002/j.1460-2075.1996.tb01053.x     Document Type: Article

References (52)

1. Axton, J.M., Dombradi, V., Cohen, P.T.W. and Glover, D.M. (1990) One of the protein phosphatase 1 isozymes in Drosophila is essential for mitosis. Cell, 63, 33-46.
2. Beach, D. and Nurse, P. (1981) High-frequency transformation of the fission yeast Schizosaccharomyces pombe. Nature, 290, 140-142.
3. Dohadwala, M., da Cruz e Silva, E.F., Hall, F.L., Williams, R.T., Carbonard-Hall, D.A., Nairn, A.C., Greengard, P. and Berndt, N. (1994) Phosphorylation and inactivation of protein phosphatase I by cyclin-dependent kinases. Proc. Natl Acad. Sci. USA, 91, 6408-6412.
4. Doonan, J.H. and Morris, N.R. (1989) The WmG gene of Aspergillus, required for completion of anaphase, encodes a homolog of mammalian phosphoprotein phosphatase 1. Cell, 57, 987-996.
5. Funabiki, H., Yamano, H., Kumada, K., Nagao, K., Hunt, T. and Yanagida, M. (1996) Cut2 proteolysis required for sister-chromatid separation in fission yeast. Nature, 381, 438-441.
6. Ghislain, M., Udvardy, A. and Mann, C. (1993) S.cerevisiae 26S protease mutants arrest cell division in G2/metaphase. Nature, 366, 358-361.
7. Glotzer, M. (1995) The only way out of mitosis. Curr. Biol. 5, 970-972.
8. Glotzer, M., Murray, A.W. and Kirschner, M.W. (1991) Cyclin is degraded by the ubiquitin pathway. Nature, 349, 132-138.
9. Goebl, M. and Yanagida, M. (1991) The TPR snap helix: a novel protein repeat motif from mitosis to transcription. Trends Biochem. Sci., 16, 173-177.
10. Gordon, C. McGurk, G., Dillon, P., Rosen, C. and Hastie, N.D. (1993) Defective mitosis due to a mutation in the gene for a fission yeast 26S protease subunit. Nature, 366, 355-357.
11. Hagan, I. and Hyams, J.S. (1988) The use of cell division cycle mutants to investigate the control of microtubule distribution in the fission yeast Schizosaccharomyces pombe. J. Cell Sci., 89, 343-357.
12. + associates with the fission yeast spindle pole body and is essential for viability. J. Cell Biol., 129, 1033-1047.
13. Heichman, K.A. and Roberts, J.M. (1996) The yeast CDC16 and CDC27 genes restrict DNA replication to once per cell cycle. Cell, 85, 39-48.
14. Hershko, A., Ganoth, D., Pehrson, D., Palazzo, R. and Cohen, L.H. (1991) Methylated ubiquitin inhibits cyclin degradation in clam embryo extracts. J. Biol. Chem., 266, 16376-16379.
15. Hershko, A., Ganoth, D., Sudakin, V., Dahan, A., Cohen, L.H., Luca, F.C., Ruderman, J.V. and Eytan, E. (1994) Components of a system that ligates cyclin to ubiquitin and their regulation by the protein kinase cdc2. J. Biol. Chem., 269, 4940-4946.
16. Hirano, T., Funahashi, S., Uemura, T. and Yanagida, M. (1986) Isolation and characterization of Schizosaccharomyces pombe cut mutants that block nuclear division but not cytokinesis. EMBO J., 5, 2973-2979.
17. + that encodes a nuclear scaffold-like protein blocks spindle elongation in mitotic anaphase. J. Cell Biol., 106, 1171-1183.
18. +. Cell, 60, 319-328.
19. Hisamoto, N., Frederick, D.L., Sugimoto, K., Tatchell, K. and Matsumoto, K. (1995) The EGP1 gene may be a positive regulator of protein phosphatase type 1 in the growth control of Saccharomyces cerevisiae. Mol. Cell. Biol., 15, 3767-3776.
20. Hofer, F., Hollenstein, H., Janner, F., Minet, M., Thuriaux, P. and Leupold, U. (1979) The genetic fine structure of nonsense suppressor in Schizosaccharomyces pombe. I. sup3 and sup9. Curr. Genet., 1, 45-61.
21. Holloway, S., Glotzer, M., King, R.W. and Murray, A.W. (1993) Anaphase is initiated by proteolysis rather than by the inactivation of maturation-promoting factor. Cell, 73, 1393-1402.
22. Irniger, S., Piatti, S. and Nasmyth, K. (1995) Genes involved in sister chromatid separation are needed for B-type cyclin proteolysis in budding yeast. Cell, 81, 269-278.
23. Ito, H., Fukuda, Y., Murata, K. and Kimura, A. (1983) Transformation of intact yeast cells treated with alkalications. J. Bacteriol., 153, 163-168.
24. King, R.W., Peters, J.-M., Tugendreich, S., Rolfe, M., Hieter, P. and Kirschner, M.W. ( 1995) A 20S complex containing CDC27 and CDC16 catalyzes the mitosis-specific conjugation of ubiquitin to cyclin B. Cell, 81, 279-288.
25. Kinoshita, N., Ohkura, H. and Yanagida, M. (1990) Distinct, essential roles of type 1 and 2A protein phosphatases in the control of the fission yeast cell division cycle. Cell, 63, 405-415.
26. Kinoshita, N. et al. (1991) Sister-chromatid separation and protein dephosphorylation in mitosis. Cold Spring Harbor Symp. Quant. Biol., 56, 621-628.
27. Kumada, K., Su, S., Yanagida, M. and Toda, T. (1995). Fission yeast TPR-family protein nuc2 is required for G1-arrest upon nitrogen starvation and is an inhibitor of septum formation. J. Cell Sci., 108, 895-905.
28. Lamb, J.R., Michaud, W.A., Sikorski, R.S. and Hieter, P.A. (1994) Cdc16p, Cdc23p and Cdc27p form a complex essential for mitosis. EMBO J. 13, 4321-4328.
29. MacKelvie, S.H., Andrews, P.D. and Stark, M.J.R. (1995) The Saccharomyces cerevisiae gene SDS22 encodes a potential regulator of the mitotic function of yeast type 1 protein phosphatase. Mol. Cell. Biol., 15, 3777-3785.
30. MacNeil, S.A. and Fantes, P.A. (1993) Methods for analysis of the fission yeast cell cycle. In Fantes, P. and Brooks, R. (eds), The Cell Cycle: A Practical Approach. IRL Press at Oxford University Press, Oxford, UK, pp. 93-125.
31. Maundrell, K. (1990) nmt1 of fission yeast. J. Biol. Chem., 265, 10857-10864.
32. Mitchison, J.M. (1970) Physiological and cytological methods for Schizosaccharomyces pombe. Methods Cell Physiol., 4, 131-165.
33. Mizukami, T. et al. (1993) A 13 kb resolution cosmid map of the 14 Mb fission yeast genome by nonrandom sequence-tagged site mapping. Cell, 73, 121-132.
34. dis1, which is required for sister chromatid separation, is a novel microtubule and spindle pole body-associating protein phosphorylated at the Cdc2 target sites. Genes Dev., 9, 1572-1585.
35. + essential for a midmitotic transition encodes a leucine-rich repeat protein that positively modulates protein phosphatase-1. Cell, 64, 149-157.
36. Ohkura, H., Adachi, Y. Kinoshita, N., Niwa, O., Toda, T. and Yanagida, M. (1988) Cold-sensitive and caffeine supersensitive mutants of the Schizosacharomyces pombe dis genes implicated in sister chromatid separation during mitosis. EMBO J., 7, 1465-1473.
37. + gene required for chromosome disjoining encodes one of two putative type 1 protein phosphatases. Cell, 57, 997-1007.
38. Renouf, S., Beullens, M., Wera, S., Van Eynde, A., Sikela, J., Stalmans, W. and Bollen, M. (1995) Molecular cloning of a human polypeptide related to yeast sds22, a regulator of protein phosphatase-1. FEBS Lett., 375, 75-78.
39. Rothstein, R.J. (1983) One-step gene disruption in yeast. Methods Enzymol., 101, 202-211.
40. + to initiate anaphase. J. Cell Biol., 127, 1655-1670.
41. Sikorski, R.S., Boguski, M.S., Goebl, M. and Hieter, P. (1990) A repeating amino acid motif in CDC23 defines a family of proteins and a new relationship among genes required for mitosis and RNA synthesis. Cell, 60, 307-317.
42. Stone, E.M., Yamano, H., Kinoshita, N. and Yanagida, M. (1993) Mitotic regulation of protein phosphatases by the fission yeast sds22 protein. Curr. Biol. 3, 13-26.
43. Studier, F.W. and Moffat, B.A. (1986) Use of bacteriophage T7 RNA polymerase to direct selective high-level expression of cloned genes. J. Mol. Biol., 189, 113-130.
44. Sudakin, V., Ganoth, D., Dahan, A., Heller, H., Hershko, J., Luca, F., Ruderman, J.V. and Hershko, A. (1995) The cyclosome, a large complex containing cyclin-selective ubiquitin ligase activity, targets cyclins for destruction at the end of mitosis. Mol. Biol. Cell, 6, 185-198.
45. Surana, U., Amon, A., Dowzer, C., McGrew, J., Byers, B. and Nasmyth, K. (1993) Destruction of the CDC28/CLB mitotic kinase is not required for the metaphase to anaphase transition in budding yeast. EMBO J., 12, 1969-1978.
46. Towbin, H., Staehelin, T. and Gordon, J. (1979) Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets; procedure and some applications. Proc. Natl Acad. Sci. USA, 76, 4350-4354.
47. Tugendreich, S., Tomkiel, J., Earnshaw, W. and Hieter, P. (1995) The CDC27HS protein co-localizes with the CDC16HS protein to the centrosome and mitotic spindle and is essential for the metaphase to anaphase transition. Cell, 81, 261-268.
48. Wilson, R. et al. (1994) 2.2 Mb of contiguous nucleotide sequence from chromosome III of C.elegans. Nature 368, 32-38.
49. Woods, A., Sherwin, T., Sasse, R., McRae, T.H., Baines, A.J. and Gull, K. (1989) Definition of individual components within the cytoskeleton of Trypanosoma brucei by a library of monoclonal antibodies. J. Cell Sci., 93, 491-500.
50. Yamano, H., Ishii, K. and Yanagida, M. (1994) Phosphorylation of dis2 protein phosphatase at the C-terminal cdc2 consensus and its potential role in cell cycle regulation. EMBO J., 13, 5310-5318.
51. Yanagida, M. (1989) Gene products required for chromosome separation. In Brooks, P., Fantes, P., Hunt, T. and Wheatley, D. (eds), The Cell Cycle. Journal of Cell Science Supplement. The Company of Biologists, Cambridge, UK, pp. 213-229.
52. Yanagida, M. (1995) Frontier questions about sister chromatin separation in anaphase. BioEssays, 17, 519-526.