-
1
-
-
0344330996
-
Molecular cloning of the von Hippel-Lindau tumor suppressor gene and its role in renal carcinoma
-
Gnarra JR, Duan DR, Weng Y et al. Molecular cloning of the von Hippel-Lindau tumor suppressor gene and its role in renal carcinoma. Biochim Biophys Acta 1996; 1242: 201-10.
-
(1996)
Biochim Biophys Acta
, vol.1242
, pp. 201-210
-
-
Gnarra, J.R.1
Duan, D.R.2
Weng, Y.3
-
2
-
-
0029825306
-
Interaction of von Hippel-Lindau tumor suppressor gene product with elongin
-
Pause A, Aso T, Linehan WM et al. Interaction of von Hippel-Lindau tumor suppressor gene product with elongin. Methods Enzymol 1996; 274: 436-41.
-
(1996)
Methods Enzymol
, vol.274
, pp. 436-441
-
-
Pause, A.1
Aso, T.2
Linehan, W.M.3
-
3
-
-
0030953635
-
The von Hippel-Lindau tumor-suppressor gene product forms a stable complex with human CUL-2, a member of the Cdc53 family of proteins
-
Pause A, Lee S, Worrell RA et al. The von Hippel-Lindau tumor-suppressor gene product forms a stable complex with human CUL-2, a member of the Cdc53 family of proteins. Proc Natl Acad Sci USA 1997; 94: 2156-61.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 2156-2161
-
-
Pause, A.1
Lee, S.2
Worrell, R.A.3
-
4
-
-
0029953780
-
cul-1 is required for cell cycle exit in C. elegans and identifies a novel gene family
-
Kipreos ET, Lander LE, Wing JP et al. cul-1 is required for cell cycle exit in C. elegans and identifies a novel gene family. Cell 1996; 85: 829-39.
-
(1996)
Cell
, vol.85
, pp. 829-839
-
-
Kipreos, E.T.1
Lander, L.E.2
Wing, J.P.3
-
5
-
-
0029024015
-
Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27
-
Pagano M, Tam SW, Theodoras AM et al. Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27. Science 1995; 269: 682-5.
-
(1995)
Science
, vol.269
, pp. 682-685
-
-
Pagano, M.1
Tam, S.W.2
Theodoras, A.M.3
-
6
-
-
0029785838
-
Post-transcriptional regulation of vascular endothelial growth factor mRNA by the product of the VHL tumor suppressor gene
-
Gnarra JR, Zhou S, Merrill MJ et al. Post-transcriptional regulation of vascular endothelial growth factor mRNA by the product of the VHL tumor suppressor gene. Proc Natl Acad Sci USA 1996; 93: 10589-94.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 10589-10594
-
-
Gnarra, J.R.1
Zhou, S.2
Merrill, M.J.3
-
8
-
-
0030848192
-
Frequency of Smad gene mutations in human cancers
-
Riggins GJ, Kinzler KW, Vogelstein B et al. Frequency of Smad gene mutations in human cancers. Cancer Res 1997; 57: 2578-80.
-
(1997)
Cancer Res
, vol.57
, pp. 2578-2580
-
-
Riggins, G.J.1
Kinzler, K.W.2
Vogelstein, B.3
-
9
-
-
0029834067
-
Partnership between DPC4 and SMAD proteins in TGF-beta signalling pathways
-
Lagna G, Hata A, Hemmati-Brivanlou A et al. Partnership between DPC4 and SMAD proteins in TGF-beta signalling pathways. Nature 1996; 383: 832-6.
-
(1996)
Nature
, vol.383
, pp. 832-836
-
-
Lagna, G.1
Hata, A.2
Hemmati-Brivanlou, A.3
-
10
-
-
0030837455
-
A structural basis for mutational inactivation of the tumour suppressor Smad4
-
Shi Y, Hata A, Lo R, Massague J et al. A structural basis for mutational inactivation of the tumour suppressor Smad4. Nature 1997; 388: 87-93.
-
(1997)
Nature
, vol.388
, pp. 87-93
-
-
Shi, Y.1
Hata, A.2
Lo, R.3
Massague, J.4
-
11
-
-
0029964257
-
Taxol induces bcl-2 phosphorylation and death of prostate cancer cells
-
Haldar S, Chintapalli J, Croce CM. Taxol induces bcl-2 phosphorylation and death of prostate cancer cells. Cancer Res 1996; 56: 1253-5.
-
(1996)
Cancer Res
, vol.56
, pp. 1253-1255
-
-
Haldar, S.1
Chintapalli, J.2
Croce, C.M.3
-
12
-
-
0031558022
-
The FHIT gene, a multiple tumor suppressor gene encompassing the carcinogen sensitive chromosome fragile site, FRA3B
-
Huebner K, Hadaczek P, Siprashvili Z et al. The FHIT gene, a multiple tumor suppressor gene encompassing the carcinogen sensitive chromosome fragile site, FRA3B. Biochim Biophys Acta 1997; 1332: M65-M70.
-
(1997)
Biochim Biophys Acta
, vol.1332
-
-
Huebner, K.1
Hadaczek, P.2
Siprashvili, Z.3
-
13
-
-
0030974681
-
Association between cigarette smoking and FHIT gene alterations in lung cancer
-
Sozzi G, Sard L, De Gregorio L et al. Association between cigarette smoking and FHIT gene alterations in lung cancer. Cancer Res 1997; 57: 2121-3.
-
(1997)
Cancer Res
, vol.57
, pp. 2121-2123
-
-
Sozzi, G.1
Sard, L.2
De Gregorio, L.3
-
14
-
-
0030936323
-
PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast and prostate cancer
-
Li J, Clifford Y, Liaw D et al. PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast and prostate cancer. Science 1997; 275: 1943-7.
-
(1997)
Science
, vol.275
, pp. 1943-1947
-
-
Li, J.1
Clifford, Y.2
Liaw, D.3
-
15
-
-
0031004088
-
Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome
-
Liaw D, Marsh DJ, Dahia PL et al. Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome. Nature Genet 1997; 16: 64-7.
-
(1997)
Nature Genet
, vol.16
, pp. 64-67
-
-
Liaw, D.1
Marsh, D.J.2
Dahia, P.L.3
-
16
-
-
0028972375
-
p65cdc18 plays a major role controlling the initiation of DNA replication in fission yeast
-
Nishitani H, Nurse P. p65cdc18 plays a major role controlling the initiation of DNA replication in fission yeast. Cell 1995; 83: 397-405.
-
(1995)
Cell
, vol.83
, pp. 397-405
-
-
Nishitani, H.1
Nurse, P.2
-
17
-
-
0030612753
-
Accumulation of p/6INK4a in mouse fibroblasts as a function of replicative senescence and not of retinoblastoma gene status
-
Palmero I, McConnell B, Parry D et al. Accumulation of p/6INK4a in mouse fibroblasts as a function of replicative senescence and not of retinoblastoma gene status. Oncogene 1997; 15: 495-503.
-
(1997)
Oncogene
, vol.15
, pp. 495-503
-
-
Palmero, I.1
McConnell, B.2
Parry, D.3
-
18
-
-
0030916209
-
Inhibition of cyclin D1 phosphorylation on threonine-286 prevents its rapid degradation via the ubiquitin-proteasome pathway
-
Diehl JA, Zindy F, Sherr CJ. Inhibition of cyclin D1 phosphorylation on threonine-286 prevents its rapid degradation via the ubiquitin-proteasome pathway. Genes Dev 1997; 11: 957-72.
-
(1997)
Genes Dev
, vol.11
, pp. 957-972
-
-
Diehl, J.A.1
Zindy, F.2
Sherr, C.J.3
-
19
-
-
16944363001
-
Decreased levels of the cell-cycle inhibitor p27/Kipl protein: Prognostic implications in primary breast cancer
-
Catzavelos C, Bhattacharya N, Ung YC et al. Decreased levels of the cell-cycle inhibitor p27/Kipl protein: Prognostic implications in primary breast cancer. Nature Med 1997; 3: 227-30.
-
(1997)
Nature Med
, vol.3
, pp. 227-230
-
-
Catzavelos, C.1
Bhattacharya, N.2
Ung, Y.C.3
-
20
-
-
0030947356
-
High level expression of p27(kip1) and cyclin D1 in some human breast cancer cells: Inverse correlation between the expression of p27(kip1) and degree of malignancy in human breast and colorectal cancers
-
Fredersdorf S, Burns J. Milne AM et al. High level expression of p27(kip1) and cyclin D1 in some human breast cancer cells: Inverse correlation between the expression of p27(kip1) and degree of malignancy in human breast and colorectal cancers. Proc Natl Acad Sci USA 1997; 94: 6380-5.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 6380-6385
-
-
Fredersdorf, S.1
Burns, J.2
Milne, A.M.3
-
21
-
-
0031048236
-
Increased proteasome-dependent degradation of the cyclin-dependent kinase inhibitor p27 in aggressive colorectal carcinomas
-
Loda M, Cukor B, Tam SW et al. Increased proteasome-dependent degradation of the cyclin-dependent kinase inhibitor p27 in aggressive colorectal carcinomas. Nature Med 1997; 3: 231-4.
-
(1997)
Nature Med
, vol.3
, pp. 231-234
-
-
Loda, M.1
Cukor, B.2
Tam, S.W.3
-
22
-
-
0031048716
-
Expression of cell-cycle regulators p27/Kipl and cyclin E, alone or in combination, correlate with survival in young breast cancer patients
-
Porter PL, Malone KE, Heagerty PJ et al. Expression of cell-cycle regulators p27/Kipl and cyclin E, alone or in combination, correlate with survival in young breast cancer patients. Nature Med 1997; 3: 222-5.
-
(1997)
Nature Med
, vol.3
, pp. 222-225
-
-
Porter, P.L.1
Malone, K.E.2
Heagerty, P.J.3
-
23
-
-
0029822745
-
Growth arrest by the cyclin-dependent kinase inhibitor p27/Kipl is abrogated by c-myc
-
Vlach J, Hennecke S, Alevizopoulos K et al. Growth arrest by the cyclin-dependent kinase inhibitor p27/Kipl is abrogated by c-myc. EMBO J 1996; 15: 6595-604.
-
(1996)
EMBO J
, vol.15
, pp. 6595-6604
-
-
Vlach, J.1
Hennecke, S.2
Alevizopoulos, K.3
-
24
-
-
0029949784
-
E2F1 functions in mice to promote apoptosis and suppress proliferation
-
Field SJ, Tsai FY, Kuo A et al. E2F1 functions in mice to promote apoptosis and suppress proliferation. Cell 1996; 85: 549-61.
-
(1996)
Cell
, vol.85
, pp. 549-561
-
-
Field, S.J.1
Tsai, F.Y.2
Kuo, A.3
-
25
-
-
0029888359
-
Tumor induction and tissue atrophy in mice lacking E2F1
-
Yamasaki L, Jacks T, Bronson R et al. Tumor induction and tissue atrophy in mice lacking E2F1. Cell 1996; 85: 537-48.
-
(1996)
Cell
, vol.85
, pp. 537-548
-
-
Yamasaki, L.1
Jacks, T.2
Bronson, R.3
-
26
-
-
0030850752
-
E2F1-induced apoptosis requires DNA binding but not transactivation and is inhibited by the retinoblastoma protein through direct interaction
-
Hsieh JK, Fredersdorf S, Kouzarides T et al. E2F1-induced apoptosis requires DNA binding but not transactivation and is inhibited by the retinoblastoma protein through direct interaction. Genes Dev 1997; 11: 1840-52.
-
(1997)
Genes Dev
, vol.11
, pp. 1840-1852
-
-
Hsieh, J.K.1
Fredersdorf, S.2
Kouzarides, T.3
-
27
-
-
0028226679
-
Induction versus progression of brain tumour development: Differential functions for the pRb- and p53-targeting domains of SV40 T antigen
-
Saenz Robles MT, Symonds H, Chen J et al. Induction versus progression of brain tumour development: Differential functions for the pRb- and p53-targeting domains of SV40 T antigen. Mol Cell Biol 1994; 14: 2686-98.
-
(1994)
Mol Cell Biol
, vol.14
, pp. 2686-2698
-
-
Saenz Robles, M.T.1
Symonds, H.2
Chen, J.3
-
28
-
-
0028169994
-
p53-dependent apoptosis suppresses tumor growth and progression in vivo
-
Symonds H, Krall L, Remington L et al. p53-dependent apoptosis suppresses tumor growth and progression in vivo. Cell 1994; 78: 703-11.
-
(1994)
Cell
, vol.78
, pp. 703-711
-
-
Symonds, H.1
Krall, L.2
Remington, L.3
-
29
-
-
0028859541
-
Bax-deficient mice with lymphoid hyperplasia and male germ cell death
-
Knudson CM, Tung KSK, Tourtelotte WG et al. Bax-deficient mice with lymphoid hyperplasia and male germ cell death. Science 1995; 270: 96-9.
-
(1995)
Science
, vol.270
, pp. 96-99
-
-
Knudson, C.M.1
Tung, K.S.K.2
Tourtelotte, W.G.3
-
30
-
-
0030905284
-
Mdm2 promotes the rapid degradation of p53
-
Haupt Y, Maya R, Kazaz A et al. Mdm2 promotes the rapid degradation of p53. Nature 1997; 387: 296-9.
-
(1997)
Nature
, vol.387
, pp. 296-299
-
-
Haupt, Y.1
Maya, R.2
Kazaz, A.3
-
32
-
-
0030829781
-
Pim-2 transgene induces lymphoid tumours, exhibiting potent synergy with c-myc
-
Allen JD, Verhoeven E, Domen J et al. Pim-2 transgene induces lymphoid tumours, exhibiting potent synergy with c-myc. Oncogene 1997; 15: 1133-41.
-
(1997)
Oncogene
, vol.15
, pp. 1133-1141
-
-
Allen, J.D.1
Verhoeven, E.2
Domen, J.3
-
33
-
-
0031050261
-
Identification of Bmi-1-interacting proteins as constituents of a multimeric mammalian polycomb complex
-
Alkema MJ, Bronk M,Verhoeven E et al. Identification of Bmi-1-interacting proteins as constituents of a multimeric mammalian polycomb complex. Genes Dev 1997; 11: 226-40.
-
(1997)
Genes Dev
, vol.11
, pp. 226-240
-
-
Alkema, M.J.1
Bronk, M.2
Verhoeven, E.3
-
34
-
-
0030057305
-
Expression of the MN antigen in cervical papanicolaou smears is an early diagnostic biomarker of cervical dysplasia
-
Liao SY, Stanbridge EJ. Expression of the MN antigen in cervical papanicolaou smears is an early diagnostic biomarker of cervical dysplasia. Cancer Epidemiol Biomarkers Prev 1996; 5: 549-57.
-
(1996)
Cancer Epidemiol Biomarkers Prev
, vol.5
, pp. 549-557
-
-
Liao, S.Y.1
Stanbridge, E.J.2
-
35
-
-
0030835515
-
Identification of the MN/CA9 protein as a reliable diagnostic biomarker of clear cell carcinoma of the kidney
-
Liao SY, Aurelio ON, Jan K et al. Identification of the MN/CA9 protein as a reliable diagnostic biomarker of clear cell carcinoma of the kidney. Cancer Res 1997; 57: 2827-31.
-
(1997)
Cancer Res
, vol.57
, pp. 2827-2831
-
-
Liao, S.Y.1
Aurelio, O.N.2
Jan, K.3
-
36
-
-
0030804368
-
High resolution analysis of chromosome 3p alterations in cervical carcinoma
-
Larson AA, Kern S, Curtiss S et al. High resolution analysis of chromosome 3p alterations in cervical carcinoma. Cancer Res 1997; 57: 4082-90.
-
(1997)
Cancer Res
, vol.57
, pp. 4082-4090
-
-
Larson, A.A.1
Kern, S.2
Curtiss, S.3
|