-
3
-
-
0028304143
-
Activation of src family kinase Lck following CD28 crosslinking in the Jurkat leukemic cell line
-
August, A., and B. Dupont. 1994. Activation of src family kinase Lck following CD28 crosslinking in the Jurkat leukemic cell line. Biochem. Biophys. Res. Commun. 199:1466-1473.
-
(1994)
Biochem. Biophys. Res. Commun.
, vol.199
, pp. 1466-1473
-
-
August, A.1
Dupont, B.2
-
4
-
-
0029810388
-
Differential association of protein tyrosine kinases with the T cell receptor is linked to induction of anergy and its prevention by B7 family-mediated costimulation
-
Boussiotis, V. A., D. L. Barber, B. J. Lee, J. G. Gribben, G. J. Freeman, and L. M. Nadler. 1996. Differential association of protein tyrosine kinases with the T cell receptor is linked to induction of anergy and its prevention by B7 family-mediated costimulation. J. Exp. Med. 184:365-376.
-
(1996)
J. Exp. Med.
, vol.184
, pp. 365-376
-
-
Boussiotis, V.A.1
Barber, D.L.2
Lee, B.J.3
Gribben, J.G.4
Freeman, G.J.5
Nadler, L.M.6
-
5
-
-
0029024880
-
The ras GTPase-activating protein (GAP) is an SH3 domain-binding protein and substrate for the Src-related tyrosine kinase, Hck
-
Briggs, S. D., S. S. Bryant, R. Jove, S. D. Sanderson, and T. E. Smithgall. 1995 The ras GTPase-activating protein (GAP) is an SH3 domain-binding protein and substrate for the Src-related tyrosine kinase, Hck. J. Biol. Chem. 270:14718-14724.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 14718-14724
-
-
Briggs, S.D.1
Bryant, S.S.2
Jove, R.3
Sanderson, S.D.4
Smithgall, T.E.5
-
6
-
-
0000082758
-
Phosphorylation of SLP-76 by the ZAP-70 protein tyrosine kinase is required for T cell receptor function
-
Bubeck-Wardenburg, J., C. F. Fu, J. Jackman, H. Flotow, S. Wilkinson, D. Williams, G. H. Kong, R. Johnson, A. C. Chan, and P. Findell. 1996. Phosphorylation of SLP-76 by the ZAP-70 protein tyrosine kinase is required for T cell receptor function. J. Biol. Chem. 271:19641-19644.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 19641-19644
-
-
Bubeck-Wardenburg, J.1
Fu, C.F.2
Jackman, J.3
Flotow, H.4
Wilkinson, S.5
Williams, D.6
Kong, G.H.7
Johnson, R.8
Chan, A.C.9
Findell, P.10
-
7
-
-
0000722327
-
New nomenclature for the Reth motif (or ARH1/TAM/ ARAM/YXXL)
-
Cambier, J. C. 1995. New nomenclature for the Reth motif (or ARH1/TAM/ ARAM/YXXL). Immunol. Today 16:110.
-
(1995)
Immunol. Today
, vol.16
, pp. 110
-
-
Cambier, J.C.1
-
8
-
-
0028288927
-
Role of protein tyrosine kinases and protein tyrosine phosphatases in T cell antigen receptor signal transduction
-
Chan, A., D. M. Desai, and A. Weiss. 1994. Role of protein tyrosine kinases and protein tyrosine phosphatases in T cell antigen receptor signal transduction. Annu. Rev. Immunol. 12:555-592.
-
(1994)
Annu. Rev. Immunol.
, vol.12
, pp. 555-592
-
-
Chan, A.1
Desai, D.M.2
Weiss, A.3
-
9
-
-
0028340167
-
ZAP-70 protein tyrosine kinase deficiency in an autosomal recessive form of severe combined immunodeficiency
-
Chan, A., T. Kadlecek, M. Elder, A. Filipovich, J. Grey, M. Iwashima, T. Parslow, and A. Weiss. 1994. ZAP-70 protein tyrosine kinase deficiency in an autosomal recessive form of severe combined immunodeficiency. Science 264:1599-1601.
-
(1994)
Science
, vol.264
, pp. 1599-1601
-
-
Chan, A.1
Kadlecek, T.2
Elder, M.3
Filipovich, A.4
Grey, J.5
Iwashima, M.6
Parslow, T.7
Weiss, A.8
-
10
-
-
0029071585
-
Activation of ZAP-70 kinase activity by phosphorylation of tyrosine 493 is required for lymphocyte antigen receptor function
-
Chan A. C., M. Dalton, R. Johnson, G.-H. Kong, T. Wang, R. Thoma, and T. Kurosaki. 1995. Activation of ZAP-70 kinase activity by phosphorylation of tyrosine 493 is required for lymphocyte antigen receptor function. EMBO J. 14:2499-2508.
-
(1995)
EMBO J.
, vol.14
, pp. 2499-2508
-
-
Chan, A.C.1
Dalton, M.2
Johnson, R.3
Kong, G.-H.4
Wang, T.5
Thoma, R.6
Kurosaki, T.7
-
11
-
-
0030175744
-
Regulation of antigen receptor signal transduction by protein tyrosine kinases
-
Chan, A. C., and A. S. Shaw. 1996. Regulation of antigen receptor signal transduction by protein tyrosine kinases. Curr. Opin. Immunol. 8:394-401.
-
(1996)
Curr. Opin. Immunol.
, vol.8
, pp. 394-401
-
-
Chan, A.C.1
Shaw, A.S.2
-
12
-
-
0030886836
-
Arrested development of double negative thymocytes in mice lacking both the Syk and ZAP-70 tyrosine kinases
-
Cheng, A. M., I. Negishi, S. J. Anderson, A. C. Chan, J. Bolen, D. Y. Loh, and T. Pawson. 1997. Arrested development of double negative thymocytes in mice lacking both the Syk and ZAP-70 tyrosine kinases. Proc. Natl. Acad. Sci. USA 94:9797-9801.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 9797-9801
-
-
Cheng, A.M.1
Negishi, I.2
Anderson, S.J.3
Chan, A.C.4
Bolen, J.5
Loh, D.Y.6
Pawson, T.7
-
13
-
-
0029952988
-
The Syk protein tyrosine kinase can function independently of CD45 or Lck in T cell antigen receptor signaling
-
Chu, D. H., H. Spits, J.-F. Peyron, R. B. Rowley, J. B. Bolen, and A. Weiss. 1996. The Syk protein tyrosine kinase can function independently of CD45 or Lck in T cell antigen receptor signaling. EMBO J. 15:6251-6261.
-
(1996)
EMBO J.
, vol.15
, pp. 6251-6261
-
-
Chu, D.H.1
Spits, H.2
Peyron, J.-F.3
Rowley, R.B.4
Bolen, J.B.5
Weiss, A.6
-
14
-
-
0029962938
-
Physical and functional interaction of Nef with Lck. HIV-1 Nef-induced T-cell signaling defects
-
Collette, Y., H. Dutartre, A. Benziane, F. Romas-Morales, R. Benarous, M. Harris, and D. Olive. 1996. Physical and functional interaction of Nef with Lck. HIV-1 Nef-induced T-cell signaling defects. J. Biol. Chem. 271:6333-6341.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 6333-6341
-
-
Collette, Y.1
Dutartre, H.2
Benziane, A.3
Romas-Morales, F.4
Benarous, R.5
Harris, M.6
Olive, D.7
-
16
-
-
0029746173
-
Regulation of the Lck SH2 domain by tyrosine phosphorylation
-
Couture, C., Z. Songyang, T. Jascur, S. Williams, P. Tailor, L. C. Cantley, and T. Mustelin. 1996. Regulation of the Lck SH2 domain by tyrosine phosphorylation. J. Biol. Chem. 271:24880-24884.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 24880-24884
-
-
Couture, C.1
Songyang, Z.2
Jascur, T.3
Williams, S.4
Tailor, P.5
Cantley, L.C.6
Mustelin, T.7
-
18
-
-
0028239074
-
Clustering of the high affinity Fc receptor for immunoglobulin G (Fc gamma RI) results in phosphorylation of its gamma-chain
-
Duchemin, A. M., L. K. Ernst, and C. L. Anderson. 1994. Clustering of the high affinity Fc receptor for immunoglobulin G (Fc gamma RI) results in phosphorylation of its gamma-chain. J. Biol. Chem. 269:12111-12117.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 12111-12117
-
-
Duchemin, A.M.1
Ernst, L.K.2
Anderson, C.L.3
-
20
-
-
0028292001
-
Human severe combined immunodeficiency due to a defect in ZAP-70 - a T-cell receptor-associated tyrosine kinase
-
Elder, M., D. Lin, J. Clever, A. Chan, T. Hope, A. Weiss, and T. Parslow. 1994. Human severe combined immunodeficiency due to a defect in ZAP-70 - a T-cell receptor-associated tyrosine kinase. Science 264:1596-1599.
-
(1994)
Science
, vol.264
, pp. 1596-1599
-
-
Elder, M.1
Lin, D.2
Clever, J.3
Chan, A.4
Hope, T.5
Weiss, A.6
Parslow, T.7
-
21
-
-
0031042637
-
Syk kinase activation by a src kinase-initiated activation loop phosphorylation chain reaction
-
El-Hillal, O., T. Kurosaki, H. Yamamura, J.-P. Kinet, and A. M. Scharenberg. 1997. syk kinase activation by a src kinase-initiated activation loop phosphorylation chain reaction. Proc. Natl. Acad. Sci. USA 94:1919-1924.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 1919-1924
-
-
El-Hillal, O.1
Kurosaki, T.2
Yamamura, H.3
Kinet, J.-P.4
Scharenberg, A.M.5
-
22
-
-
0024004720
-
Purification of a RAS-responsive adenylyl cyclase complex from Saccharomyces cerevisiae by use of an epitope addition method
-
Field J., J.-I. Nikawa, D. Broek, B. MacDonald, L. Rodgers, I. A. Wilson, R. A. Lerner and M. Wigler. 1988. Purification of a RAS-responsive adenylyl cyclase complex from Saccharomyces cerevisiae by use of an epitope addition method. Mol. Cell. Biol. 8:2159-2165.
-
(1988)
Mol. Cell. Biol.
, vol.8
, pp. 2159-2165
-
-
Field, J.1
Nikawa, J.-I.2
Broek, D.3
MacDonald, B.4
Rodgers, L.5
Wilson, I.A.6
Lerner, R.A.7
Wigler, M.8
-
23
-
-
0029051695
-
The SH3 domain-binding T cell tyrosyl phosphoprotein p120. Demonstration of its identity with the c-cbl protooncogene product and in vivo complexes with Fyn, Grb2, and phosphatidylinositol 3-kinase
-
Fukazawa, T., K. A. Reedquist, T. Trub, S. Soltoff, G. Panchamoorthy, B. Druker, L. Cantley, S. E. Shoelson, and H. Band. 1995. The SH3 domain-binding T cell tyrosyl phosphoprotein p120. Demonstration of its identity with the c-cbl protooncogene product and in vivo complexes with Fyn, Grb2, and phosphatidylinositol 3-kinase. J. Biol. Chem. 270:19141-19150.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 19141-19150
-
-
Fukazawa, T.1
Reedquist, K.A.2
Trub, T.3
Soltoff, S.4
Panchamoorthy, G.5
Druker, B.6
Cantley, L.7
Shoelson, S.E.8
Band, H.9
-
25
-
-
0029087530
-
Absence of ZAP-70 prevents signaling through the antigen receptor on peripheral blood T cells but not on thymocytes
-
Gelfand, E. W., K. Weiberg, B. D. Mazer, T. A. Kadlecek, and A. Weiss. 1995. Absence of ZAP-70 prevents signaling through the antigen receptor on peripheral blood T cells but not on thymocytes. J. Exp. Med. 182:1057-1065.
-
(1995)
J. Exp. Med.
, vol.182
, pp. 1057-1065
-
-
Gelfand, E.W.1
Weiberg, K.2
Mazer, B.D.3
Kadlecek, T.A.4
Weiss, A.5
-
26
-
-
0029989312
-
Functional lck is required for optimal CD28-mediated activation of the tec family tyrosine kinase EMT/ITK
-
Gibson, S., A. August, D. Branch, B. Dupont, and G. M. Mills. 1996. Functional lck is required for optimal CD28-mediated activation of the tec family tyrosine kinase EMT/ITK. J. Biol. Chem. 271:7079-7083.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 7079-7083
-
-
Gibson, S.1
August, A.2
Branch, D.3
Dupont, B.4
Mills, G.M.5
-
27
-
-
0030584837
-
The EMT/ITK/TSK (EMT) tyrosine kinase is activated during TCR signaling: Lck is required for optimal activation of EMT
-
Gibson, S., A. August, Y. Kawakami, T. Kawakami, B. Dupont, and G. B. Mills. 1996. The EMT/ITK/TSK (EMT) tyrosine kinase is activated during TCR signaling: Lck is required for optimal activation of EMT. J. Immunol. 156:2716-2722.
-
(1996)
J. Immunol.
, vol.156
, pp. 2716-2722
-
-
Gibson, S.1
August, A.2
Kawakami, Y.3
Kawakami, T.4
Dupont, B.5
Mills, G.B.6
-
28
-
-
0023429078
-
Isolation and characterization of a T-lymphocyte somatic mutant with altered signal transduction by the antigen receptor
-
Goldsmith, M. A., and A. Weiss. 1987. Isolation and characterization of a T-lymphocyte somatic mutant with altered signal transduction by the antigen receptor. Proc. Natl. Acad. Sci. USA 84:6879-6883.
-
(1987)
Proc. Natl. Acad. Sci. USA
, vol.84
, pp. 6879-6883
-
-
Goldsmith, M.A.1
Weiss, A.2
-
30
-
-
0030863780
-
Proximity and orientation underlie signaling by the non-receptor tyrosine kinase ZAP-70
-
Graef, I. A., L. J. Holsinger, S. Diver, S. L. Schreiber, and G. Crabtree. 1997. Proximity and orientation underlie signaling by the non-receptor tyrosine kinase ZAP-70. EMBO J. 16:5618-5628.
-
(1997)
EMBO J.
, vol.16
, pp. 5618-5628
-
-
Graef, I.A.1
Holsinger, L.J.2
Diver, S.3
Schreiber, S.L.4
Crabtree, G.5
-
31
-
-
0030294283
-
Fyn can partially substitute for Lck in T lymphocyte development
-
Groves, T., P. Smiley, M. P. Cooke, K. Forbush, R. M. Perlmutter, and C. J. Guidos. 1996. Fyn can partially substitute for Lck in T lymphocyte development. Immunity 5:417-428.
-
(1996)
Immunity
, vol.5
, pp. 417-428
-
-
Groves, T.1
Smiley, P.2
Cooke, M.P.3
Forbush, K.4
Perlmutter, R.M.5
Guidos, C.J.6
-
32
-
-
0028203261
-
Activation-dependent phosphorylation of the T-lymphocyte surface receptor CD28 and associated proteins
-
Hutchcroft, J. E., and B. E. Bierer. 1994. Activation-dependent phosphorylation of the T-lymphocyte surface receptor CD28 and associated proteins. Proc. Natl. Acad. Sci. USA 91:3260-3264.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 3260-3264
-
-
Hutchcroft, J.E.1
Bierer, B.E.2
-
33
-
-
0028209548
-
The sequential interaction of two cytoplasmic protein tyrosine kinases in T cell antigen receptor signaling
-
Iwashima, M., B. Irving, N. van Oers, A. Chan, and A. Weiss. 1994. The sequential interaction of two cytoplasmic protein tyrosine kinases in T cell antigen receptor signaling. Science 263:1136-1139.
-
(1994)
Science
, vol.263
, pp. 1136-1139
-
-
Iwashima, M.1
Irving, B.2
Van Oers, N.3
Chan, A.4
Weiss, A.5
-
35
-
-
0026611039
-
lck deficiency on the growth and cytolytic effector function of an interleukin-2-dependent cytotoxic T-cell line
-
lck deficiency on the growth and cytolytic effector function of an interleukin-2-dependent cytotoxic T-cell line. Mol. Cell. Biol. 12:4521-4530.
-
(1992)
Mol. Cell. Biol.
, vol.12
, pp. 4521-4530
-
-
Karnitz, L.1
Sutor, S.L.2
Torigoe, T.3
Reed, J.C.4
Bell, M.P.5
McKean, D.J.6
Leibson, P.J.7
Abraham, R.T.8
-
36
-
-
0026630060
-
Expression of the human epidermal growth factor receptor in a murine T-cell hybridoma. A transmembrane protein tyrosine kinase can synergize with the T-cell antigen receptor
-
Kennedy, I. C., C. H. June, and J. J. O'Shea. 1992. Expression of the human epidermal growth factor receptor in a murine T-cell hybridoma. A transmembrane protein tyrosine kinase can synergize with the T-cell antigen receptor. J. Biol. Chem. 267:4924-4929.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 4924-4929
-
-
Kennedy, I.C.1
June, C.H.2
O'Shea, J.J.3
-
37
-
-
0029864882
-
syk by tyrosine phosphorylation or by binding of phosphorylated immunoreceptor tyrosine-based activation motif peptides
-
syk by tyrosine phosphorylation or by binding of phosphorylated immunoreceptor tyrosine-based activation motif peptides. Mol. Cell. Biol. 16:1471-1478.
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 1471-1478
-
-
Kimura, T.1
Sakamoto, H.2
Appella, E.3
Siraganian, R.P.4
-
38
-
-
0027185152
-
T cell activation by clustered tyrosine kinases
-
Kolanus, W., C. Romeo, and B. Seed. 1993. T cell activation by clustered tyrosine kinases. Cell 74:171-184.
-
(1993)
Cell
, vol.74
, pp. 171-184
-
-
Kolanus, W.1
Romeo, C.2
Seed, B.3
-
39
-
-
0029783430
-
Distinct tyrosine phosphorylation sites in ZAP-70 mediate activation and negative regulation of antigen receptor function
-
Kong, G., M. Dalton, J. B. Wardenburg, D. Straus, T. Kurosaki, and A. C. Chan. 1996. Distinct tyrosine phosphorylation sites in ZAP-70 mediate activation and negative regulation of antigen receptor function. Mol. Cell. Biol. 16:5026-5035.
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 5026-5035
-
-
Kong, G.1
Dalton, M.2
Wardenburg, J.B.3
Straus, D.4
Kurosaki, T.5
Chan, A.C.6
-
40
-
-
0029076731
-
Reconstitution of syk function by the ZAP-70 protein tyrosine kinase
-
Kong, G. H., J. Y. Bu, T. Kurosaki, A. S. Shaw, and A. C. Chan. 1995. Reconstitution of syk function by the ZAP-70 protein tyrosine kinase. Immunity 2:485-492.
-
(1995)
Immunity
, vol.2
, pp. 485-492
-
-
Kong, G.H.1
Bu, J.Y.2
Kurosaki, T.3
Shaw, A.S.4
Chan, A.C.5
-
41
-
-
0345720492
-
Role of Syk autophosphorylation site and SH2 domains in B cell antigen receptor function
-
Kurosaki, T., S. A. Johnson, L. Pao, K. Sada, H. Yamamura, and J. C. Cambier. 1996. Role of Syk autophosphorylation site and SH2 domains in B cell antigen receptor function. J. Exp. Med. 182:1816-1821.
-
(1996)
J. Exp. Med.
, vol.182
, pp. 1816-1821
-
-
Kurosaki, T.1
Johnson, S.A.2
Pao, L.3
Sada, K.4
Yamamura, H.5
Cambier, J.C.6
-
42
-
-
0031172201
-
Interaction between the SH2 domains of ZAP-70 and the tyrosine-based activation motif 1 sequence of the zeta subunit of the T-cell receptor
-
Labadia, M. E., S. Jakes, C. A. Grygon, D. J. Greenwood, J. Schembri-King, S. M. Lukas, T. C. Warren, and R. H. Ingraham. 1997. Interaction between the SH2 domains of ZAP-70 and the tyrosine-based activation motif 1 sequence of the zeta subunit of the T-cell receptor. Arch. Biochem. Biophys. 342:117-125.
-
(1997)
Arch. Biochem. Biophys.
, vol.342
, pp. 117-125
-
-
Labadia, M.E.1
Jakes, S.2
Grygon, C.A.3
Greenwood, D.J.4
Schembri-King, J.5
Lukas, S.M.6
Warren, T.C.7
Ingraham, R.H.8
-
43
-
-
0029788103
-
Differential intrinsic enzymatic activity of Syk and ZAP-70 protein-tyrosine kinases
-
Latour, S., L. M. L. Chow, and A. Veillette. 1996. Differential intrinsic enzymatic activity of Syk and ZAP-70 protein-tyrosine kinases. J. Biol. Chem. 271:22782-22790.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 22782-22790
-
-
Latour, S.1
Chow, L.M.L.2
Veillette, A.3
-
44
-
-
0030795305
-
Regulation of T-cell antigen receptor signalling by Syk tyrosine protein kinase
-
Latour, S., M. Fournel, and A. Veillette. 1997. Regulation of T-cell antigen receptor signalling by Syk tyrosine protein kinase. Mol. Cell. Biol. 17:4434-4441.
-
(1997)
Mol. Cell. Biol.
, vol.17
, pp. 4434-4441
-
-
Latour, S.1
Fournel, M.2
Veillette, A.3
-
45
-
-
0031229746
-
The lck SH2 phosphotyrosine binding site is critical for efficient TCR-induced processive tyrosine phosphorylation of the zeta chain and IL-2 production
-
Lewis, L. A., C. D. Chung, J. Y. Chen, J. R. Parnes, M. Moran, V. P. Patel, and M. C. Miceli. 1997. The lck SH2 phosphotyrosine binding site is critical for efficient TCR-induced processive tyrosine phosphorylation of the zeta chain and IL-2 production. J. Immunol. 159:2292-2300.
-
(1997)
J. Immunol.
, vol.159
, pp. 2292-2300
-
-
Lewis, L.A.1
Chung, C.D.2
Chen, J.Y.3
Parnes, J.R.4
Moran, M.5
Patel, V.P.6
Miceli, M.C.7
-
46
-
-
9544246859
-
Disruption of epithelial gamma delta T cell repertoires by mutation of the Syk tyrosine kinase
-
Mallick-Wood, C. A., W. Pao, A. M. Cheng, J. M. Lewis, S. Klukarni, J. B. Bolen, B. Rowley, R. E. Rigelaar, T. Pawson, and A. C. Hayday. 1996. Disruption of epithelial gamma delta T cell repertoires by mutation of the Syk tyrosine kinase. Proc. Natl. Acad. Sci. USA 93:9704-9709.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 9704-9709
-
-
Mallick-Wood, C.A.1
Pao, W.2
Cheng, A.M.3
Lewis, J.M.4
Klukarni, S.5
Bolen, J.B.6
Rowley, B.7
Rigelaar, R.E.8
Pawson, T.9
Hayday, A.C.10
-
47
-
-
0031017838
-
Activation of the Src-family tyrosine kinase by SH3 domain displacement
-
Moarefi, I., M. LaFevre-Bernt, F. Sicheri, M. Huse, C.-H. Lee, J. Kuriyan, and W. T. Miller. 1997. Activation of the Src-family tyrosine kinase by SH3 domain displacement. Nature 385:650-653.
-
(1997)
Nature
, vol.385
, pp. 650-653
-
-
Moarefi, I.1
LaFevre-Bernt, M.2
Sicheri, F.3
Huse, M.4
Lee, C.-H.5
Kuriyan, J.6
Miller, W.T.7
-
48
-
-
0026522204
-
lck
-
lck. Nature 357:161-164.
-
(1992)
Nature
, vol.357
, pp. 161-164
-
-
Molina, T.J.1
Kishihara, K.2
Siderovski, D.P.3
Van Ewijk, W.4
Narendran, A.5
Timms, E.6
Wakeham, A.7
Paige, C.J.8
Hartmann, K.U.9
Veillette, A.10
Davidson, D.11
Mak, T.W.12
-
49
-
-
0029133646
-
Essential role for ZAP-70 in both positive and negative selection of thymocytes
-
Negishi, I., N. Motoyama, K.-I. Nakayama, K. Nakayama, S. Senju, S. Hatakeyama, Q. Zhang, A. C. Chan, and D. Y. Loh. 1995. Essential role for ZAP-70 in both positive and negative selection of thymocytes. Nature 376: 435-438.
-
(1995)
Nature
, vol.376
, pp. 435-438
-
-
Negishi, I.1
Motoyama, N.2
Nakayama, K.-I.3
Nakayama, K.4
Senju, S.5
Hatakeyama, S.6
Zhang, Q.7
Chan, A.C.8
Loh, D.Y.9
-
50
-
-
0029031806
-
Binding of ZAP-70 to phosphorylated T-cell receptor ζ and η enhances its autophosphorylation and generates specific binding sites for SH2 domain-containing proteins
-
Neumeister, E. N., Y. Zhu, S. Richard, C. Terhorst, A. C. Chan, and A. Y. Shaw. 1995. Binding of ZAP-70 to phosphorylated T-cell receptor ζ and η enhances its autophosphorylation and generates specific binding sites for SH2 domain-containing proteins. Mol. Cell. Biol. 15:3171-3178.
-
(1995)
Mol. Cell. Biol.
, vol.15
, pp. 3171-3178
-
-
Neumeister, E.N.1
Zhu, Y.2
Richard, S.3
Terhorst, C.4
Chan, A.C.5
Shaw, A.Y.6
-
51
-
-
0030002817
-
Characterization of the roles of SH2 domain-containing proteins in T-lymphocyte activation by using dominant negative SH2 domains
-
Northrop, J. P., M. J. Pustelnik, A. T. Lu, and J. R. Grove. 1996. Characterization of the roles of SH2 domain-containing proteins in T-lymphocyte activation by using dominant negative SH2 domains. Mol. Cell. Biol. 16: 2255-2263.
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 2255-2263
-
-
Northrop, J.P.1
Pustelnik, M.J.2
Lu, A.T.3
Grove, J.R.4
-
52
-
-
0029832707
-
Differential regulation of activation-induced tyrosine phosphorylation and recruitment of SLP-76 to Vav by distinct isoforms of the CD45 protein-tyrosine phosphatase
-
Onodera, H., D. G. Motto, G. A. Koretzky, and D. M. Rothstein. 1996. Differential regulation of activation-induced tyrosine phosphorylation and recruitment of SLP-76 to Vav by distinct isoforms of the CD45 protein-tyrosine phosphatase. J. Biol. Chem. 271:22225-22230.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 22225-22230
-
-
Onodera, H.1
Motto, D.G.2
Koretzky, G.A.3
Rothstein, D.M.4
-
53
-
-
0029904138
-
Direct regulation of ZAP-70 by SHP-1 in T cell antigen receptor signaling
-
Plas, D. R., R. Johnson, J. T. Pingel, R. J. Matthews, M. Dalton, G. Roy, A. C. Chan, and M. L. Thomas. 1996. Direct regulation of ZAP-70 by SHP-1 in T cell antigen receptor signaling. Science 272:1173-1176.
-
(1996)
Science
, vol.272
, pp. 1173-1176
-
-
Plas, D.R.1
Johnson, R.2
Pingel, J.T.3
Matthews, R.J.4
Dalton, M.5
Roy, G.6
Chan, A.C.7
Thomas, M.L.8
-
55
-
-
0030046923
-
Dominant-negative zeta-associated protein 70 inhibits T cell antigen receptor signaling
-
Qian, D., M. N. Mollenauer, and A. Weiss. 1996. Dominant-negative zeta-associated protein 70 inhibits T cell antigen receptor signaling. J. Exp. Med. 183:611-620.
-
(1996)
J. Exp. Med.
, vol.183
, pp. 611-620
-
-
Qian, D.1
Mollenauer, M.N.2
Weiss, A.3
-
56
-
-
0030906543
-
Regulation of Vav-SLP-76 binding by ZAP-70 and its relevance to TCRζ/CD3 induction of interleukin-2
-
Raab, M., J. da Silva, P. R. Findell, and C. E. Rudd. 1997. Regulation of Vav-SLP-76 binding by ZAP-70 and its relevance to TCRζ/CD3 induction of interleukin-2. Immunity 6:155-164.
-
(1997)
Immunity
, vol.6
, pp. 155-164
-
-
Raab, M.1
Da Silva, J.2
Findell, P.R.3
Rudd, C.E.4
-
57
-
-
0028905060
-
Syk is activated by phosphotyrosine-containing peptides representing the tyrosine-based activation motifs of the high affinity receptor for IgE
-
Shiue, L., M. J. Zoller, and J. S. Brugge. 1995. Syk is activated by phosphotyrosine-containing peptides representing the tyrosine-based activation motifs of the high affinity receptor for IgE. J. Biol. Chem. 270:10498-10502.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 10498-10502
-
-
Shiue, L.1
Zoller, M.J.2
Brugge, J.S.3
-
58
-
-
0031034930
-
Crystal structure of the Src-family tyrosine kinase Hck
-
Sicheri, F., I. Moarefi, and J. Kuriyan. 1997. Crystal structure of the Src-family tyrosine kinase Hck. Nature 385:602-609.
-
(1997)
Nature
, vol.385
, pp. 602-609
-
-
Sicheri, F.1
Moarefi, I.2
Kuriyan, J.3
-
59
-
-
0027389272
-
CD45 specifically modulates binding of Lck to a phosphopeptide encompassing the negative regulatory tyrosine of Lck
-
Sieh, M., J. B. Bolen, and A. Weiss. 1993. CD45 specifically modulates binding of Lck to a phosphopeptide encompassing the negative regulatory tyrosine of Lck. EMBO J. 12:315-321.
-
(1993)
EMBO J.
, vol.12
, pp. 315-321
-
-
Sieh, M.1
Bolen, J.B.2
Weiss, A.3
-
60
-
-
0029933309
-
Altered peptide ligand-induced partial T cell activation: Molecular mechanisms and role in T cell biology
-
Sloan-Lancaster, J., and P. M. Allen. 1996. Altered peptide ligand-induced partial T cell activation: molecular mechanisms and role in T cell biology. Annu. Rev. Immunol. 14:1-27.
-
(1996)
Annu. Rev. Immunol.
, vol.14
, pp. 1-27
-
-
Sloan-Lancaster, J.1
Allen, P.M.2
-
61
-
-
0029939787
-
SH2 domain function is essential for the role of the lck tyrosine kinase in T cell receptor signal transduction
-
Straus, D., A. C. Chan, B. Patai, and A. Weiss. 1996. SH2 domain function is essential for the role of the lck tyrosine kinase in T cell receptor signal transduction. J. Biol. Chem. 271:9976-9981.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 9976-9981
-
-
Straus, D.1
Chan, A.C.2
Patai, B.3
Weiss, A.4
-
62
-
-
0026705903
-
Genetic evidence for the involvement of the lck tyrosine kinase in signal transduction through the T cell antigen receptor
-
Straus, D., and A. Weiss. 1992. Genetic evidence for the involvement of the lck tyrosine kinase in signal transduction through the T cell antigen receptor. Cell 70:585-593.
-
(1992)
Cell
, vol.70
, pp. 585-593
-
-
Straus, D.1
Weiss, A.2
-
65
-
-
0031016575
-
Differential activation of the tyrosine kinases ZAP-70 and Syk after Fc gamma RI stimulation
-
Taylor, N., T. Jahn, S. Smith, T. Lamkin, L. Uribe, Y. Liu, D. L. Durden, and K. Weinberg. 1997. Differential activation of the tyrosine kinases ZAP-70 and Syk after Fc gamma RI stimulation. Blood 89:388-396.
-
(1997)
Blood
, vol.89
, pp. 388-396
-
-
Taylor, N.1
Jahn, T.2
Smith, S.3
Lamkin, T.4
Uribe, L.5
Liu, Y.6
Durden, D.L.7
Weinberg, K.8
-
67
-
-
0029658306
-
vav associates with tyrosine-phosphorylated SLP-76 in antigen-stimulated T cells
-
vav associates with tyrosine-phosphorylated SLP-76 in antigen-stimulated T cells. J. Exp. Med. 184: 1161-1166.
-
(1996)
J. Exp. Med.
, vol.184
, pp. 1161-1166
-
-
Tuosto, L.1
Michel, F.2
Acuto, O.3
-
68
-
-
0030293791
-
αβ T cell development is abolished in mice lacking both lck and fyn protein tyrosine kinases
-
van Oers, N. S. C., B. Lowin-Kropf, D. Finlay, K. Connolly, and A. Weiss. 1996. αβ T cell development is abolished in mice lacking both lck and fyn protein tyrosine kinases. Immunity 5:429-436.
-
(1996)
Immunity
, vol.5
, pp. 429-436
-
-
Van Oers, N.S.C.1
Lowin-Kropf, B.2
Finlay, D.3
Connolly, K.4
Weiss, A.5
-
70
-
-
0029151944
-
Activating and inhibitory mutations in adjacent tyrosines in the kinase domain of ZAP-70
-
Wange, R. L., R. Guitian, N. Isakov, J. D. Watts, R. Aebersold, and L. E. Samuelson. 1995. Activating and inhibitory mutations in adjacent tyrosines in the kinase domain of ZAP-70. J. Biol. Chem. 270:18730-18733.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 18730-18733
-
-
Wange, R.L.1
Guitian, R.2
Isakov, N.3
Watts, J.D.4
Aebersold, R.5
Samuelson, L.E.6
-
71
-
-
0030250114
-
Complex complexes: Signaling at the TCR
-
Wange, R. L., and L. E. Samelson. 1996. Complex complexes: signaling at the TCR. Immunity 5:197-205.
-
(1996)
Immunity
, vol.5
, pp. 197-205
-
-
Wange, R.L.1
Samelson, L.E.2
-
72
-
-
0000987148
-
Antigen presentation by supported planar membranes containing affinity-purified I-Ad
-
Watts, T. H., A. A. Brian, J. W. Kappler, P. Marrack, and H. McConnell. 1984. Antigen presentation by supported planar membranes containing affinity-purified I-Ad. Proc. Natl. Acad. Sci. USA 81:7564-7568.
-
(1984)
Proc. Natl. Acad. Sci. USA
, vol.81
, pp. 7564-7568
-
-
Watts, T.H.1
Brian, A.A.2
Kappler, J.W.3
Marrack, P.4
McConnell, H.5
-
74
-
-
0021678703
-
Requirement for the coexpression of T3 and the T cell antigen receptor on a malignant human T cell line
-
Weiss, A., and J. D. Stobo. 1984. Requirement for the coexpression of T3 and the T cell antigen receptor on a malignant human T cell line. J. Exp. Med. 160:1284-1299.
-
(1984)
J. Exp. Med.
, vol.160
, pp. 1284-1299
-
-
Weiss, A.1
Stobo, J.D.2
-
75
-
-
0030970079
-
Reconstitution of T cell antigen receptor-induced Erk2 kinase activation in Lck-negative JCaM1 cells by Syk
-
Williams, S., C. Couture, J. Gilman, T. Jascur, M. Deckert, A. Altman, and T. Mustelin. 1997. Reconstitution of T cell antigen receptor-induced Erk2 kinase activation in Lck-negative JCaM1 cells by Syk. Eur. J. Biochem. 245: 84-90.
-
(1997)
Eur. J. Biochem.
, vol.245
, pp. 84-90
-
-
Williams, S.1
Couture, C.2
Gilman, J.3
Jascur, T.4
Deckert, M.5
Altman, A.6
Mustelin, T.7
-
76
-
-
0001584956
-
Vav and SLP-76 interact and are functionally cooperative in IL-2 gene activation
-
Wu, J., D. G. Motto, G. A. Koretzky, and A. Weiss. 1996. Vav and SLP-76 interact and are functionally cooperative in IL-2 gene activation. Immunity 4:593-602.
-
(1996)
Immunity
, vol.4
, pp. 593-602
-
-
Wu, J.1
Motto, D.G.2
Koretzky, G.A.3
Weiss, A.4
-
77
-
-
0027257445
-
A kinase-independent function of Lck in potentiating antigen-specific T cell activation
-
Xu, H., and D. R. Littman. 1993. A kinase-independent function of Lck in potentiating antigen-specific T cell activation. Cell 74:633-643.
-
(1993)
Cell
, vol.74
, pp. 633-643
-
-
Xu, H.1
Littman, D.R.2
-
78
-
-
0027469994
-
Identification of HS1 protein as a major substate of protein-tyrosine kinase(s) upon B-cell antigen receptor-mediated signaling
-
Yamanashi, Y., M. Okada, T. Semba, T. Yamori, H. Umemori, S. Tsunasawa, K. Toyoshima, D. Kitamura, T. Watanabe, and T. Yamamoto. 1993. Identification of HS1 protein as a major substate of protein-tyrosine kinase(s) upon B-cell antigen receptor-mediated signaling. Proc. Natl. Acad. Sci. USA 90:3631-3635.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 3631-3635
-
-
Yamanashi, Y.1
Okada, M.2
Semba, T.3
Yamori, T.4
Umemori, H.5
Tsunasawa, S.6
Toyoshima, K.7
Kitamura, D.8
Watanabe, T.9
Yamamoto, T.10
-
79
-
-
0029909498
-
The kinase, SH3, and SH2 domains of Lck play critical roles in T-cell activation after ZAP-70 membrane localization
-
Yamasaki, S., M. Takamatsu, and M. Iwashima. 1996. The kinase, SH3, and SH2 domains of Lck play critical roles in T-cell activation after ZAP-70 membrane localization. Mol. Cell. Biol. 16:7151-7160.
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 7151-7160
-
-
Yamasaki, S.1
Takamatsu, M.2
Iwashima, M.3
-
80
-
-
0024238959
-
Generation of an active protein-tyrosine kinase from lymphocytes by proteolysis
-
Zioncheck, T. F., M. L. Harrison, C. C. Isaacson, and R. L. Geahlen. 1988. Generation of an active protein-tyrosine kinase from lymphocytes by proteolysis. J. Biol. Chem. 263:19195-19202.
-
(1988)
J. Biol. Chem.
, vol.263
, pp. 19195-19202
-
-
Zioncheck, T.F.1
Harrison, M.L.2
Isaacson, C.C.3
Geahlen, R.L.4
-
81
-
-
0031568534
-
Protein tyrosine kinases Syk and ZAP-70 display distinct requirements for Src family kinases in immune response receptor signal transduction
-
Zoller, K. E., I. A. MacNeil, and J. S. Brugge. 1997. Protein tyrosine kinases Syk and ZAP-70 display distinct requirements for Src family kinases in immune response receptor signal transduction. J. Immunol. 158:1650-1659.
-
(1997)
J. Immunol.
, vol.158
, pp. 1650-1659
-
-
Zoller, K.E.1
MacNeil, I.A.2
Brugge, J.S.3
|