-
1
-
-
0029877297
-
3 dopamine receptor gene is associated with hyperactivity in mice
-
3 dopamine receptor gene is associated with hyperactivity in mice. Proc. Natl. Acad. Sci. USA 93: 1945-1949, 1996.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 1945-1949
-
-
Accili, D.1
Fishburn, C.S.2
Drago, J.3
Steiner, H.4
Lachowicz, J.E.5
Park, B.H.6
Gauda, E.B.7
Lee, E.J.8
Cool, M.H.9
Sibley, D.R.10
Gerfen, C.R.11
Westphal, H.12
Fuchs, S.13
-
2
-
-
0028592584
-
Intracerebroventricular treatment with an antisense oligodeoxy-nucleotide to kappa-opioid receptors inhibited kappa-agonist-induced analgesia in rats
-
ADAMS, J. U., X. CHEN, J. K. DERIEL, M. W. ADLER, AND C. L. LIU. Intracerebroventricular treatment with an antisense oligodeoxy-nucleotide to kappa-opioid receptors inhibited kappa-agonist-induced analgesia in rats. Brain Res. 667: 129-132, 1994.
-
(1994)
Brain Res.
, vol.667
, pp. 129-132
-
-
Adams, J.U.1
Chen, X.2
Deriel, J.K.3
Adler, M.W.4
Liu, C.L.5
-
3
-
-
0028139045
-
Reduced hippocampal long-term potentiation and context-specific deficit in associative learning in mGluR1 mutant mice
-
AIBA, A., C. CHEN, K. HERRUP, C. ROSENMUND, C. F. STEVENS, AND S. TONEGAWA. Reduced hippocampal long-term potentiation and context-specific deficit in associative learning in mGluR1 mutant mice. Cell 79: 365-375, 1994.
-
(1994)
Cell
, vol.79
, pp. 365-375
-
-
Aiba, A.1
Chen, C.2
Herrup, K.3
Rosenmund, C.4
Stevens, C.F.5
Tonegawa, S.6
-
4
-
-
0028216462
-
Antisense knockouts: Molecular scalpels for the dissection of signal transduction
-
ALBERT, P. R., AND S. J. MORRIS. Antisense knockouts: molecular scalpels for the dissection of signal transduction. Trends Pharmacol. Sci. 15: 250-254, 1994.
-
(1994)
Trends Pharmacol. Sci.
, vol.15
, pp. 250-254
-
-
Albert, P.R.1
Morris, S.J.2
-
5
-
-
0000136416
-
2 receptor knockout mice
-
2 receptor knockout mice. Biochem. Biophys, Res. Commun, 224: 625-630, 1996.
-
(1996)
Biochem. Biophys, Res. Commun
, vol.224
, pp. 625-630
-
-
Alfie, M.E.1
Yang, X.P.2
Hess, F.3
Carretero, O.A.4
-
7
-
-
0027316203
-
Site-directed point mutations in embryonic stem cells: A gene-targeting tag-and-exchange strategy
-
ASKEW, G. R., T. DOETSCHMAN, AND J. B. LINGREL. Site-directed point mutations in embryonic stem cells: a gene-targeting tag-and-exchange strategy. Mol. Cell. Biol. 13: 4115-4124, 1993.
-
(1993)
Mol. Cell. Biol.
, vol.13
, pp. 4115-4124
-
-
Askew, G.R.1
Doetschman, T.2
Lingrel, J.B.3
-
8
-
-
0029165456
-
2 receptors
-
2 receptors. Nature 377: 424-428, 1995.
-
(1995)
Nature
, vol.377
, pp. 424-428
-
-
Baik, J.H.1
Picetti, R.2
Saiardi, A.3
Thiriet, G.4
Dierich, A.5
Depaulis, A.6
Le, M.M.7
Borrelli, E.8
-
9
-
-
0028609612
-
Interaction of endothelin-3 with endothelin-B receptor is essential for development of epidermal melanocytes and enteric neurons
-
BAYNASH, A. G., K. HOSODA, A. GIAID, J. A. RICHARDSON, N. EMOTO, R. E. HAMMER, AND M. YANAGISAWA. Interaction of endothelin-3 with endothelin-B receptor is essential for development of epidermal melanocytes and enteric neurons. Cell 79: 1277-1285, 1994.
-
(1994)
Cell
, vol.79
, pp. 1277-1285
-
-
Baynash, A.G.1
Hosoda, K.2
Giaid, A.3
Richardson, J.A.4
Emoto, N.5
Hammer, R.E.6
Yanagisawa, M.7
-
11
-
-
0027370057
-
Specific atrial overexpression of G protein coupled human beta 1 adrenoceptors in transgenic mice
-
BERTIN, B., P. MANSIER, I. MAKEH, P. BRIAND, W. ROSTENE, B. SWYNGHEDAUW, AND A. D. STROSBERG. Specific atrial overexpression of G protein coupled human beta 1 adrenoceptors in transgenic mice. Cardiouosc. Res. 27: 1606-1612, 1993.
-
(1993)
Cardiouosc. Res.
, vol.27
, pp. 1606-1612
-
-
Bertin, B.1
Mansier, P.2
Makeh, I.3
Briand, P.4
Rostene, W.5
Swynghedauw, B.6
Strosberg, A.D.7
-
12
-
-
0030424478
-
Characterization of antinociception to opioid receptor selective agonists after antisense oligodeoxynucleotide-mediated "knock-down" of opioid receptor in vivo
-
BILSKY, E. J., R. N. BERNSTEIN, V. J. HRUBY, R. B. ROTHMAN, J. LAI, AND F. PORRECA. Characterization of antinociception to opioid receptor selective agonists after antisense oligodeoxynucleotide-mediated "knock-down" of opioid receptor in vivo. J. Pharmacol Exp. Ther. 277: 491-501, 1996.
-
(1996)
J. Pharmacol Exp. Ther.
, vol.277
, pp. 491-501
-
-
Bilsky, E.J.1
Bernstein, R.N.2
Hruby, V.J.3
Rothman, R.B.4
Lai, J.5
Porreca, F.6
-
13
-
-
0028987954
-
Physiological effects of inverse agonists in transgenic mice with myocardial overexpression of the beta 2-adrenoceptor
-
BOND, R. A., P. LEFF, T. D. JOHNSON, C. A. MILANO, H. A. ROCKMAN, T. R. MCMINN, S. APPARSUNDARAM, M. F. HYEK, T. P. KENAKIN, L. F. ALLEN, AND R. J. LEFKOWITZ. Physiological effects of inverse agonists in transgenic mice with myocardial overexpression of the beta 2-adrenoceptor (see comments). Nature 374: 272-276, 1995.
-
(1995)
Nature
, vol.374
, pp. 272-276
-
-
Bond, R.A.1
Leff, P.2
Johnson, T.D.3
Milano, C.A.4
Rockman, H.A.5
Mcminn, T.R.6
Apparsundaram, S.7
Hyek, M.F.8
Kenakin, T.P.9
Allen, L.F.10
Lefkowitz, R.J.11
-
14
-
-
0028979356
-
2 bradykinin receptor gene in mice eliminates bradykinin action in smooth muscle and neurons
-
2 bradykinin receptor gene in mice eliminates bradykinin action in smooth muscle and neurons. J. Biol. Chem. 270: 13706-13710, 1995.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 13706-13710
-
-
Borkowsm, J.A.1
Ransom, R.W.2
Seabrook, G.R.3
Trumbauer, M.4
Chen, H.5
Hill, R.G.6
Strader, C.D.7
Hess, J.P.8
-
15
-
-
0028981113
-
6 receptor in the rat brain: A study using antisense oligonucleotides
-
6 receptor in the rat brain: a study using antisense oligonucleotides. J, Pharmacol. Exp. Ther. 274: 173-180, 1995.
-
(1995)
J, Pharmacol. Exp. Ther.
, vol.274
, pp. 173-180
-
-
Bourson, A.1
Borroni, E.2
Austin, R.H.3
Monsma, F.J.4
Sleight, A.J.5
-
16
-
-
0029816638
-
Neurogenic amplification of immune complex inflammation
-
BOZIC, C. R., B. LU, U. E. HOPKEN, C. GERARD, AND N. P. GERARD. Neurogenic amplification of immune complex inflammation. Science 273: 1722-1725, 1996.
-
(1996)
Science
, vol.273
, pp. 1722-1725
-
-
Bozic, C.R.1
Lu, B.2
Hopken, U.E.3
Gerard, C.4
Gerard, N.P.5
-
17
-
-
0029786931
-
Single-copy transgenic mice with chosen-site integration
-
BRONSON, S. K., E. G. PLAEHN, K. D. KLUCKMAN, J. R. HAGAMAN, N. MAEDA, AND O. SMITHIES. Single-copy transgenic mice with chosen-site integration. Proc. Natl Acad. Sci. USA 93: 9067-9072, 1996.
-
(1996)
Proc. Natl Acad. Sci. USA
, vol.93
, pp. 9067-9072
-
-
Bronson, S.K.1
Plaehn, E.G.2
Kluckman, K.D.3
Hagaman, J.R.4
Maeda, N.5
Smithies, O.6
-
18
-
-
0030273253
-
General anosmia caused by a targeted disruption of the mouse olfactory cyclic nucleotidegated cation channel
-
BRUNET, L. J., G. H. GOLD, AND J. NGAI. General anosmia caused by a targeted disruption of the mouse olfactory cyclic nucleotidegated cation channel. Neuron 17: 681-693, 1996.
-
(1996)
Neuron
, vol.17
, pp. 681-693
-
-
Brunet, L.J.1
Gold, G.H.2
Ngai, J.3
-
19
-
-
0028095670
-
Targeted gene replacement
-
CAPECCHI, M. R. Targeted gene replacement. Sci. Am. 270: 52-59, 1994.
-
(1994)
Sci. Am.
, vol.270
, pp. 52-59
-
-
Capecchi, M.R.1
-
20
-
-
0027521914
-
Apoptosis: Final common pathway of photoreceptor death in rd, rds, and rhodopsin mutant mice
-
CHANG, G. Q., Y. HAO, AND F. WONG. Apoptosis: final common pathway of photoreceptor death in rd, rds, and rhodopsin mutant mice. Neuron 11: 595-605, 1993.
-
(1993)
Neuron
, vol.11
, pp. 595-605
-
-
Chang, G.Q.1
Hao, Y.2
Wong, F.3
-
21
-
-
0028985401
-
An antisense oligodeoxynucleotide to muopioid receptors inhibits mu-opioid receptor agonist-induced analgesia in rats
-
CHEN, X. H., J. U. ADAMS, E. B. GELLER, J. K. DERIEL, M. W. ADLER, AND C. L. LIU. An antisense oligodeoxynucleotide to muopioid receptors inhibits mu-opioid receptor agonist-induced analgesia in rats. Eur. J. Pharmacol. 275: 105-108, 1995.
-
(1995)
Eur. J. Pharmacol.
, vol.275
, pp. 105-108
-
-
Chen, X.H.1
Adams, J.U.2
Geller, E.B.3
Deriel, J.K.4
Adler, M.W.5
Liu, C.L.6
-
22
-
-
0027318238
-
Structural elements of G alpha subunits that interact with G beta gamma, receptors, and effectors
-
CONKLIN, B. R., AND H. R. BOURNE. Structural elements of G alpha subunits that interact with G beta gamma, receptors, and effectors. Cell 73: 631-641, 1993.
-
(1993)
Cell
, vol.73
, pp. 631-641
-
-
Conklin, B.R.1
Bourne, H.R.2
-
23
-
-
0030008312
-
Role of the thrombin receptor in development and evidence for a second receptor
-
CONNOLLY, A. J., H. ISHIHARA, M. L. KAHN, R. J. FARESE, AND S. R. COUGHLIN. Role of the thrombin receptor in development and evidence for a second receptor. Nature 381: 516-519, 1996.
-
(1996)
Nature
, vol.381
, pp. 516-519
-
-
Connolly, A.J.1
Ishihara, H.2
Kahn, M.L.3
Farese, R.J.4
Coughlin, S.R.5
-
24
-
-
0027997686
-
Motor deficit and impairment of synaptic plasticity in mice lacking mGluR1
-
CONQUET, F., Z. I. BASHIR, C. H. DAVIES, H. DANIEL, F. FERRAGUTI, F. BORDI, B. K. FRANZ, A. REGGIANI, V. MATARESE, F. CONDE, G. L. COLLINGRIDGE, AND F. CREPEL. Motor deficit and impairment of synaptic plasticity in mice lacking mGluR1. Nature 372: 237-243, 1994.
-
(1994)
Nature
, vol.372
, pp. 237-243
-
-
Conquet, F.1
Bashir, Z.I.2
Davies, C.H.3
Daniel, H.4
Ferraguti, F.5
Bordi, F.6
Franz, B.K.7
Reggiani, A.8
Matarese, V.9
Conde, F.10
Collingridge, G.L.11
Crepel, F.12
-
25
-
-
0029776391
-
1B serotonin receptors
-
1B serotonin receptors. Nat. Genet. 14: 98-101, 1996.
-
(1996)
Nat. Genet.
, vol.14
, pp. 98-101
-
-
Crabbe, J.C.1
Phillips, T.J.2
Feller, D.J.3
Hen, R.4
Wenger, C.D.5
Lessov, C.N.6
Schafer, G.L.7
-
26
-
-
0030000245
-
Progress in antisense oligonucleotide therapeutics
-
CROOKE, S. T., AND C. F. BENNETT. Progress in antisense oligonucleotide therapeutics. Annu. Rev. Pharmacol. Toxicol 36: 107-129, 1996.
-
(1996)
Annu. Rev. Pharmacol. Toxicol
, vol.36
, pp. 107-129
-
-
Crooke, S.T.1
Bennett, C.F.2
-
27
-
-
0030971394
-
Cardiovascular indexes in the conscious mouse at rest and with exercise: New tools to study transgenic models of cardiac disease
-
Heart Circ. Physiol 41
-
DESAI, K. H., R. SATO, E. SCHAUBLE, G. S. BARSH, B. K. KOBILKA, AND D. BERNSTEIN. Cardiovascular indexes in the conscious mouse at rest and with exercise: new tools to study transgenic models of cardiac disease. Am. J. Physiol. 272 (Heart Circ. Physiol 41): H1053-H1061, 1997.
-
(1997)
Am. J. Physiol.
, vol.272
-
-
Desai, K.H.1
Sato, R.2
Schauble, E.3
Barsh, G.S.4
Kobilka, B.K.5
Bernstein, D.6
-
28
-
-
0027938450
-
Deletion and replacement of the mouse adult beta-globin genes by a "plug and socket" repeated targeting strategy
-
DETLOFF, P. J., J. LEWIS, S. W. JOHN, W. R. SHEHEE, R. LANGENBACH, N. MAEDA, AND O. SMITHIES. Deletion and replacement of the mouse adult beta-globin genes by a "plug and socket" repeated targeting strategy. Mol Cell Biol 14: 6936-6943, 1994.
-
(1994)
Mol Cell Biol
, vol.14
, pp. 6936-6943
-
-
Detloff, P.J.1
Lewis, J.2
John, S.W.3
Shehee, W.R.4
Langenbach, R.5
Maeda, N.6
Smithies, O.7
-
29
-
-
0028589325
-
1A dopamine receptors
-
1A dopamine receptors. Proc. Natl Acad. Sci. USA 91: 12564-12568, 1994.
-
(1994)
Proc. Natl Acad. Sci. USA
, vol.91
, pp. 12564-12568
-
-
Drago, J.1
Gerfen, C.R.2
Lachowicz, J.E.3
Steiner, H.4
Hollon, T.R.5
Love, P.E.6
Ooi, G.T.7
Grinberg, A.8
Lee, E.J.9
Huang, S.P.10
Bartlett, P.F.11
Jose, P.A.12
Sibley, D.R.13
Westphal, H.14
-
30
-
-
0029845123
-
Medical therapy can improve the biological properties of the chronically failing heart. A new era in the treatment of heart failure
-
EICHHORN, E. J., AND M. R. BRISTOW. Medical therapy can improve the biological properties of the chronically failing heart. A new era in the treatment of heart failure. Circulation 94: 2285-2296, 1996.
-
(1996)
Circulation
, vol.94
, pp. 2285-2296
-
-
Eichhorn, E.J.1
Bristow, M.R.2
-
31
-
-
0029946644
-
Sensitivity to leptin and susceptibility to seizures of mice lacking neuropeptide Y
-
ERICKSON, J. C., K. E. CLEGG, AND R. D. PALMITER. Sensitivity to leptin and susceptibility to seizures of mice lacking neuropeptide Y. Nature 381: 415-421, 1996.
-
(1996)
Nature
, vol.381
, pp. 415-421
-
-
Erickson, J.C.1
Clegg, K.E.2
Palmiter, R.D.3
-
32
-
-
0028117777
-
A system for tissue-specific gene targeting: Transgenic mice susceptible to subgroup A avian leukosis virusbased retroviral vectors
-
FEDERSPIEL, M. J., P. BATES, J. A. YOUNG, H. E. VARMUS, AND S. H. HUGHES. A system for tissue-specific gene targeting: transgenic mice susceptible to subgroup A avian leukosis virusbased retroviral vectors. Proc. Natl Acad. Sci. USA 91: 11241-11245, 1994.
-
(1994)
Proc. Natl Acad. Sci. USA
, vol.91
, pp. 11241-11245
-
-
Federspiel, M.J.1
Bates, P.2
Young, J.A.3
Varmus, H.E.4
Hughes, S.H.5
-
33
-
-
0029978506
-
Expression of transduced genes in mice generated by infecting blastocysts with avian leukosis virus-based retroviral vectors
-
FEDERSPIEL, M. J., D. A. SWING, B. EAGLESON, S. W. REID, AND S. H. HUGHES. Expression of transduced genes in mice generated by infecting blastocysts with avian leukosis virus-based retroviral vectors. Proc. Natl. Acad. Sci. USA 93: 4931-4936, 1996.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 4931-4936
-
-
Federspiel, M.J.1
Swing, D.A.2
Eagleson, B.3
Reid, S.W.4
Hughes, S.H.5
-
34
-
-
0026684238
-
2 receptors in the chakragati mouse: Neurobehavioral dysfunction in a transgenic insertional mutant
-
2 receptors in the chakragati mouse: neurobehavioral dysfunction in a transgenic insertional mutant, Brain Res. 580: 18-26, 1992.
-
(1992)
Brain Res.
, vol.580
, pp. 18-26
-
-
Fitzgerald, L.W.1
Miller, K.J.2
Ratty, A.K.3
Click, S.D.4
Teitler, M.5
Gross, K.W.6
-
35
-
-
0028071115
-
Temporal control of gene expression in transgenic mice by a tetracycline-responsive promoter
-
FURTH, P. A., O. L. ST, H. BOGER, P. GRUSS, M. GOSSEN, A. KISTNER, H. BUJARD, AND L. HENNIGHAUSEN. Temporal control of gene expression in transgenic mice by a tetracycline-responsive promoter. Proc, Natl. Acad. Sci. USA 91: 9302-9306, 1994.
-
(1994)
Proc, Natl. Acad. Sci. USA
, vol.91
, pp. 9302-9306
-
-
Furth, P.A.1
St, O.L.2
Boger, H.3
Gruss, P.4
Gossen, M.5
Kistner, A.6
Bujard, H.7
Hennighausen, L.8
-
36
-
-
0028955960
-
Echocardiographic assessment of left ventricular mass and systolic function in mice
-
GARDIN, J. M., F. M. SIRI, R. N. KTTSIS, J. G. EDWARDS, AND L. A. LEINWAND. Echocardiographic assessment of left ventricular mass and systolic function in mice. Circ. Res. 76: 907-914, 1995.
-
(1995)
Circ. Res.
, vol.76
, pp. 907-914
-
-
Gardin, J.M.1
Siri, F.M.2
Kttsis, R.N.3
Edwards, J.G.4
Leinwand, L.A.5
-
37
-
-
0028987631
-
Sα protein in the hearts of transgenic mice
-
Sα protein in the hearts of transgenic mice. J. Clin. Invest. 95: 1676-1683, 1995.
-
(1995)
J. Clin. Invest.
, vol.95
, pp. 1676-1683
-
-
Gaudin, C.1
Ishikawa, Y.2
Wight, D.C.3
Mahdavi, V.4
Nadal, G.B.5
Wagner, T.E.6
Vatner, D.E.7
Homcy, C.J.8
-
38
-
-
0029940557
-
Gene-targeting studies of mammalian behavior: Is it the mutation or the background genotype?
-
GERLAI, R. Gene-targeting studies of mammalian behavior: is it the mutation or the background genotype? Trends Neurosci. 19: 177-181, 1996.
-
(1996)
Trends Neurosci.
, vol.19
, pp. 177-181
-
-
Gerlai, R.1
-
39
-
-
0029845423
-
Comparative hemodynamic, left ventricular functional, and antiadrenergic effects of chronic treatment with metoprolol versus carvedilol in the failing heart
-
GILBERT, E. M., W. T. ABRAHAM, S. OLSEN, B. HATTLER, M. WHITE, P. MEALY, P. LARRABEE, AND M. R. BRISTOW. Comparative hemodynamic, left ventricular functional, and antiadrenergic effects of chronic treatment with metoprolol versus carvedilol in the failing heart. Circulation 94: 2817-2825, 1996.
-
(1996)
Circulation
, vol.94
, pp. 2817-2825
-
-
Gilbert, E.M.1
Abraham, W.T.2
Olsen, S.3
Hattler, B.4
White, M.5
Mealy, P.6
Larrabee, P.7
Bristow, M.R.8
-
40
-
-
0030071106
-
Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter
-
GIROS, B., M. JABER, S. R. JONES, R. M. WIGHTMAN, AND M. G. CARON. Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter. Nature 379: 606-612, 1996.
-
(1996)
Nature
, vol.379
, pp. 606-612
-
-
Giros, B.1
Jaber, M.2
Jones, S.R.3
Wightman, R.M.4
Caron, M.G.5
-
41
-
-
0028858741
-
Functional abnormalities in transgenic mice expressing a mutant rhodopsin gene
-
GOTO, Y., N. S. PEACHEY, H. RIPPS, AND M. I. NAASH. Functional abnormalities in transgenic mice expressing a mutant rhodopsin gene. Invest. Ophthalmol Visual Sci. 36: 62-71, 1995.
-
(1995)
Invest. Ophthalmol Visual Sci.
, vol.36
, pp. 62-71
-
-
Goto, Y.1
Peachey, N.S.2
Ripps, H.3
Naash, M.I.4
-
42
-
-
0028535198
-
Reporter gene expression in cones in transgenic mice carrying bovine rhodopsin promoter/lacZ transgenes
-
GOURAS, P., H. KJELDBYE, AND D. J. ZACK, Reporter gene expression in cones in transgenic mice carrying bovine rhodopsin promoter/lacZ transgenes. Vis. Neurosci. 11: 1227-1231, 1994.
-
(1994)
Vis. Neurosci.
, vol.11
, pp. 1227-1231
-
-
Gouras, P.1
Kjeldbye, H.2
Zack, D.J.3
-
44
-
-
0028059099
-
Deletion of a DNA polymerase beta gene segment in T cells using cell type-specific gene targeting
-
GU, H., J. D. MARTH, P. C. ORBAN, H. MOSSMANN, AND K. RAJEWSKY. Deletion of a DNA polymerase beta gene segment in T cells using cell type-specific gene targeting, Science 265: 103-106, 1994.
-
(1994)
Science
, vol.265
, pp. 103-106
-
-
Gu, H.1
Marth, J.D.2
Orban, P.C.3
Mossmann, H.4
Rajewsky, K.5
-
46
-
-
0029762944
-
Doppler echocardiography of normal and abnormal embryonic mouse heart
-
GUI, Y., K. K. LINASK, P. KHOWSATHIT, AND J. C. HUHTA. Doppler echocardiography of normal and abnormal embryonic mouse heart. Pediatr. Res. 40: 633-642, 1996.
-
(1996)
Pediatr. Res.
, vol.40
, pp. 633-642
-
-
Gui, Y.1
Linask, K.K.2
Khowsathit, P.3
Huhta, J.C.4
-
47
-
-
0029885744
-
Development of retroviral vectors as safe, targeted gene delivery systems
-
GUNZBURG, W. H., AND B. SALMONS. Development of retroviral vectors as safe, targeted gene delivery systems. J. Mol. Med. 74: 171-182, 1996.
-
(1996)
J. Mol. Med.
, vol.74
, pp. 171-182
-
-
Gunzburg, W.H.1
Salmons, B.2
-
48
-
-
0027333008
-
Antisense inhibition of ATi receptor mRNA and angiotensinogen mRNA in the brain of spontaneously hypertensive rats reduces hypertension of neurogenic origin
-
GYURKO, R., D. WIELBO, AND M. I. PHILLIPS. Antisense inhibition of ATi receptor mRNA and angiotensinogen mRNA in the brain of spontaneously hypertensive rats reduces hypertension of neurogenic origin. Regul. Pept. 49: 167-174, 1993.
-
(1993)
Regul. Pept.
, vol.49
, pp. 167-174
-
-
Gyurko, R.1
Wielbo, D.2
Phillips, M.I.3
-
49
-
-
0026429190
-
Introduction of a subtle mutation into the Hox-2.6 locus in embryonic stem cells
-
Erratum. Nature 353: 94, 1991
-
HASTY, P., S. R. RAMIREZ, R. KRUMLAUF, AND A. BRADLEY. Introduction of a subtle mutation into the Hox-2.6 locus in embryonic stem cells. Nature 350: 243-246, 1991. [Erratum. Nature 353: 94, 1991.]
-
(1991)
Nature
, vol.350
, pp. 243-246
-
-
Hasty, P.1
Ramirez, S.R.2
Krumlauf, R.3
Bradley, A.4
-
50
-
-
0029953818
-
Beta-adrenoceptor blocking agents for the treatment of heart failure
-
HEILBRON, B. G., AND K. G. GIN. Beta-adrenoceptor blocking agents for the treatment of heart failure. Int. J. Clin. Pharmacol Ther. 34: 231-235, 1996.
-
(1996)
Int. J. Clin. Pharmacol Ther.
, vol.34
, pp. 231-235
-
-
Heilbron, B.G.1
Gin, K.G.2
-
51
-
-
0028885773
-
Behavioural and cardiovascular effects of disrupting the angiotensin II type-2 receptor in mice
-
HEIN, L, G. S. BARSH, R. E. PRATT, V.J. DZAU, AND B. K. KOBILKA. Behavioural and cardiovascular effects of disrupting the angiotensin II type-2 receptor in mice. Nature 377: 744-747, 1995.
-
(1995)
Nature
, vol.377
, pp. 744-747
-
-
Hein, L.1
Barsh, G.S.2
Pratt, R.E.3
Dzau, V.J.4
Kobilka, B.K.5
-
52
-
-
0025339373
-
Specific regulation of gene expression by antisense, sense and antigene nucleic acids
-
HELENE, C., AND J. J. TOULME. Specific regulation of gene expression by antisense, sense and antigene nucleic acids. Biochim. Biophys. Acta 1049: 99-125, 1990.
-
(1990)
Biochim. Biophys. Acta
, vol.1049
, pp. 99-125
-
-
Helene, C.1
Toulme, J.J.2
-
53
-
-
0028845670
-
A mouse model of human familial hypocalciuric hypercalcemia and neonatal severe hyperparathyroidism
-
HO, C., D. A. CONNER, M. R. POLLAK, D. J. LADD, O. KIFOR, H. B. WARREN, E. M. BROWN, J. G. SEIDMAN, AND C. E. SEIDMAN. A mouse model of human familial hypocalciuric hypercalcemia and neonatal severe hyperparathyroidism. Nat. Genet. 11: 389-394, 1995.
-
(1995)
Nat. Genet.
, vol.11
, pp. 389-394
-
-
Ho, C.1
Conner, D.A.2
Pollak, M.R.3
Ladd, D.J.4
Kifor, O.5
Warren, H.B.6
Brown, E.M.7
Seidman, J.G.8
Seidman, C.E.9
-
54
-
-
0029154871
-
In vivo echocardiographic detection of enhanced left ventricular function in gene-targeted mice with phospholamban deficiency
-
HOIT, B. D., S. F. KHOURY, E. G. KRANIAS, N. BALL, AND R. A. WALSH. In vivo echocardiographic detection of enhanced left ventricular function in gene-targeted mice with phospholamban deficiency. Circ. Res. 77: 632-637, 1995.
-
(1995)
Circ. Res.
, vol.77
, pp. 632-637
-
-
Hoit, B.D.1
Khoury, S.F.2
Kranias, E.G.3
Ball, N.4
Walsh, R.A.5
-
55
-
-
0028639196
-
Targeted and natural (piebald-lethal) mutations of endothelin-B receptor gene produce megacolon associated with spotted coat color in mice
-
HOSODA, K, R. E. HAMMER, J. A. RICHARDSON, A. G. BAYNASH, J. C. CHEUNG, A. GIAID, AND M. YANAGISAWA. Targeted and natural (piebald-lethal) mutations of endothelin-B receptor gene produce megacolon associated with spotted coat color in mice. Cell 79: 1267-1276, 1994.
-
(1994)
Cell
, vol.79
, pp. 1267-1276
-
-
Hosoda, K.1
Hammer, R.E.2
Richardson, J.A.3
Baynash, A.G.4
Cheung, J.C.5
Giaid, A.6
Yanagisawa, M.7
-
56
-
-
0028829134
-
Evidence against a role for metabotropic glutamate receptors in mossy fiber LTP: The use of mutant mice and pharmacological antagonists
-
HSIA, A.Y., P.A. SALIN, P.E. CASTILLO, A. AIBA, A. ABELIOVICH, S. TONEGAWA, AND R. A. NICOLL. Evidence against a role for metabotropic glutamate receptors in mossy fiber LTP: the use of mutant mice and pharmacological antagonists. Neuropharmacology 34: 1567-1572, 1995.
-
(1995)
Neuropharmacology
, vol.34
, pp. 1567-1572
-
-
Hsia, A.Y.1
Salin, P.A.2
Castillo, P.E.3
Aiba, A.4
Abeliovich, A.5
Tonegawa, S.6
Nicoll, R.A.7
-
57
-
-
0027260657
-
Cellular interactions implicated in the mechanism of photoreceptor degeneration in transgenic mice expressing a mutant rhodopsin gene
-
HUANG, P. C., A. E. GAITAN, Y. HAO, R. M. FETTERS, AND F. WONG. Cellular interactions implicated in the mechanism of photoreceptor degeneration in transgenic mice expressing a mutant rhodopsin gene. Proc. Natl. Acad. Sci. USA 90: 8484-8488, 1993.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 8484-8488
-
-
Huang, P.C.1
Gaitan, A.E.2
Hao, Y.3
Fetters, R.M.4
Wong, F.5
-
59
-
-
0031045876
-
Retinopathy induced in mice by targeted disruption of the rhodopsin gene
-
HUMPHRIES, M. M., D. RANCOURT, G. J. FARRAR, P. KENNA, M. HAZEL, R. A. BUSH, P. A. SIEVING, D. M. SHEILS, N. MCNALLY, P. CREIGHTON, A. ERVEN, A. BOROS, K. GULYA, M. R. CAPECCHI, AND P. HUMPHRIES. Retinopathy induced in mice by targeted disruption of the rhodopsin gene. Nat. Genet. 15: 216-219, 1997.
-
(1997)
Nat. Genet.
, vol.15
, pp. 216-219
-
-
Humphries, M.M.1
Rancourt, D.2
Farrar, G.J.3
Kenna, P.4
Hazel, M.5
Bush, R.A.6
Sieving, P.A.7
Sheils, D.M.8
Mcnally, N.9
Creighton, P.10
Erven, A.11
Boros, A.12
Gulya, K.13
Capecchi, M.R.14
Humphries, P.15
-
60
-
-
0030889192
-
Targeted disruption of the melanocortin-4 receptor results in obesity in mice
-
HUSZAR, D., C. A. LYNCH, V. FAIRCHILD-HUNTRESS, J. H. DUNMORE, Q. FANG, L. R. BERKEMEIER, W. GU, R. A. KESTERSON, B. A. BOSTON, R. D. CONE, F. J. SMITH, L. A. CAMPFIELD, P. BURN, AND F. LEE. Targeted disruption of the melanocortin-4 receptor results in obesity in mice. Cell 88: 131-141, 1997.
-
(1997)
Cell
, vol.88
, pp. 131-141
-
-
Huszar, D.1
Lynch, C.A.2
Fairchild-Huntress, V.3
Dunmore, J.H.4
Fang, Q.5
Berkemeier, L.R.6
Gu, W.7
Kesterson, R.A.8
Boston, B.A.9
Cone, R.D.10
Smith, F.J.11
Campfield, L.A.12
Burn, P.13
Lee, F.14
-
61
-
-
0028858478
-
Effects on blood pressure and exploratory behaviour of mice lacking angiotensin II Type-2 receptor
-
ICHIKI, T., P. A. LABOSKY, C. SHIOTA, S. OKUYAMA, Y. IMAGAWA, A. FOGO, F. NIIMURA, I. ICHIKAWA, B. L. HOGAN, AND T. INAGAMI. Effects on blood pressure and exploratory behaviour of mice lacking angiotensin II Type-2 receptor. Nature 377: 748-750, 1995.
-
(1995)
Nature
, vol.377
, pp. 748-750
-
-
Ichiki, T.1
Labosky, P.A.2
Shiota, C.3
Okuyama, S.4
Imagawa, Y.5
Fogo, A.6
Niimura, F.7
Ichikawa, I.8
Hogan, B.L.9
Inagami, T.10
-
62
-
-
0029560924
-
2 receptor cDNA into rat striatum
-
2 receptor cDNA into rat striatum. Mol. Brain Res. 34: 315-320, 1995.
-
(1995)
Mol. Brain Res.
, vol.34
, pp. 315-320
-
-
Ikari, H.1
Zhang, L.2
Chernak, J.M.3
Mastrangeli, A.4
Kato, S.5
Kuo, H.6
Crystal, R.G.7
Ingram, D.K.8
Roth, G.S.9
-
63
-
-
0029847231
-
1 receptors
-
1 receptors. Proc. Natl. Acad. Sci. USA 93: 13316-13320, 1996.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 13316-13320
-
-
Inoue, I.1
Yanai, K.2
Kitamura, D.3
Taniuchi, I.4
Kobayashi, T.5
Niimura, K.6
Watanabe, T.7
Watanabe, T.8
-
64
-
-
0028952503
-
Regulation of blood pressure by the type 1A angiotensin II receptor gene
-
ITO, M., M. I. OLIVERIO, P. J. MANNON, C. F. BEST, N. MAEDA, O. SMITHIES, AND T. M. COFFMAN. Regulation of blood pressure by the type 1A angiotensin II receptor gene. Proc. Natl. Acad. Sci. USA 92: 3521-3525, 1995.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 3521-3525
-
-
Ito, M.1
Oliverio, M.I.2
Mannon, P.J.3
Best, C.F.4
Maeda, N.5
Smithies, O.6
Coffman, T.M.7
-
65
-
-
0029793010
-
Chronic control of high blood pressure in the spontaneously hypertensive rat by delivery of angiotensin type 1 receptor antisense
-
IYER, S. N., D, LU, M. J. KATOVICH, AND M. K. RAIZADA. Chronic control of high blood pressure in the spontaneously hypertensive rat by delivery of angiotensin type 1 receptor antisense. Proc. Natl. Acad. Sci. USA 93: 9960-9965, 1996.
-
(1996)
. Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 9960-9965
-
-
Iyer, S.N.1
Lu, D.2
Katovich, M.J.3
Raizada, M.K.4
-
66
-
-
0021799874
-
Constitutive and conditional suppression of exogenous and endogenous genes by anti-sense RNA
-
IZANT, J. G., AND H. WEINTRAUB. Constitutive and conditional suppression of exogenous and endogenous genes by anti-sense RNA. Science 229: 345-352, 1985.
-
(1985)
Science
, vol.229
, pp. 345-352
-
-
Izant, J.G.1
Weintraub, H.2
-
67
-
-
10544242967
-
Essential role of beta-adrenergic receptor kinase 1 in cardiac development and function
-
JABER, M., W. J. KOCH, H. ROCKMAN, B. SMITH, R. A. BOND, K. K. SULIK, J. J. ROSS, R. J. LEFKOWITZ, M. G. CARON, AND B. GIROS. Essential role of beta-adrenergic receptor kinase 1 in cardiac development and function. Proc. Natl. Acad. Sci. USA 93: 12974-12979, 1996.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 12974-12979
-
-
Jaber, M.1
Koch, W.J.2
Rockman, H.3
Smith, B.4
Bond, R.A.5
Sulik, K.K.6
Ross, J.J.7
Lefkowitz, R.J.8
Caron, M.G.9
Giros, B.10
-
68
-
-
0026563167
-
NMDAreceptor-independent long-term potentiation
-
JOHNSTON, D., S. WILLIAMS, D. JAFFE, AND R. GRAY. NMDAreceptor-independent long-term potentiation. Annu. Rev. Physiol. 54: 489-505, 1992.
-
(1992)
Annu. Rev. Physiol.
, vol.54
, pp. 489-505
-
-
Johnston, D.1
Williams, S.2
Jaffe, D.3
Gray, R.4
-
69
-
-
0028567517
-
Tissue-specific targeting of retroviral vectors through ligand-receptor interactions
-
KASAHARA, N., A. M. DOZY, AND Y. W. KAN. Tissue-specific targeting of retroviral vectors through ligand-receptor interactions. Science 266: 1373-1376, 1994.
-
(1994)
Science
, vol.266
, pp. 1373-1376
-
-
Kasahara, N.1
Dozy, A.M.2
Kan, Y.W.3
-
70
-
-
0028944631
-
Genetic control of blood pressure and the angiotensinogen locus
-
KIM, H. S., J. H. KREGE, K. D. KLUCKMAN, J. R. HAGAMAN, J. B. HODGIN, C. F. BEST, J. C. JENNETTE, T. M. COFFMAN, N. MAEDA, AND O. SMITHIES. Genetic control of blood pressure and the angiotensinogen locus. Proc. Natl. Acad. Sci. USA 92: 2735-2739, 1995.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 2735-2739
-
-
Kim, H.S.1
Krege, J.H.2
Kluckman, K.D.3
Hagaman, J.R.4
Hodgin, J.B.5
Best, C.F.6
Jennette, J.C.7
Coffman, T.M.8
Maeda, N.9
Smithies, O.10
-
71
-
-
0029763587
-
Doxycycline-mediated quantitative and tissue-specific control of gene expression in transgenic mice
-
KISTNER, A., M. GOSSEN, F. ZIMMERMANN, J. JERECIC, C. ULLMER, H. LUBBERT, AND H. BUJARD. Doxycycline-mediated quantitative and tissue-specific control of gene expression in transgenic mice. Proc. Natl. Acad. Sci. USA 93: 10933-10938, 1996.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 10933-10938
-
-
Kistner, A.1
Gossen, M.2
Zimmermann, F.3
Jerecic, J.4
Ullmer, C.5
Lubbert, H.6
Bujard, H.7
-
72
-
-
0029004532
-
Ectopic expression of the Agouti gene in transgenic mice causes obesity, features of type II diabetes, and yellow fur
-
KLEBIG, M. L., J. E. WILKINSON, J. G. GEISLER, AND R. P. WOYCHIK. Ectopic expression of the Agouti gene in transgenic mice causes obesity, features of type II diabetes, and yellow fur. Proc. Natl. Acad. Sci. USA 92: 4728-4732, 1995.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 4728-4732
-
-
Klebig, M.L.1
Wilkinson, J.E.2
Geisler, J.G.3
Woychik, R.P.4
-
73
-
-
0028858477
-
Targeted disruption of the tyrosine hydroxylase locus results in severe catecholamine depletion and perinatal lethality in mice
-
KOBAYASHI, K., S. MORITA, H. SAWADA, T. MIZUGUCHI, K. YAMADA, I. NAGATSU, T. HATA, Y. WATANABE, K. FUJITA, AND T. NAGATSU. Targeted disruption of the tyrosine hydroxylase locus results in severe catecholamine depletion and perinatal lethality in mice. J. Biol. Chem. 270: 27235-27243, 1995.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 27235-27243
-
-
Kobayashi, K.1
Morita, S.2
Sawada, H.3
Mizuguchi, T.4
Yamada, K.5
Nagatsu, I.6
Hata, T.7
Watanabe, Y.8
Fujita, K.9
Nagatsu, T.10
-
74
-
-
0029092795
-
Alteration of catecholamine phenotype in transgenic mice influences expression of adrenergic receptor subtypes
-
KOBAYASHI, K., A. OTA, A. TOGARI, S. MORITA, T. MIZUGUCHI, H. SAWADA, K. YAMADA, I. NAGATSU, S. MATSUMOTO, K. FUJITA, AND T. NAGATSU. Alteration of catecholamine phenotype in transgenic mice influences expression of adrenergic receptor subtypes. J. Neurochem. 65: 492-501, 1995.
-
(1995)
J. Neurochem.
, vol.65
, pp. 492-501
-
-
Kobayashi, K.1
Ota, A.2
Togari, A.3
Morita, S.4
Mizuguchi, T.5
Sawada, H.6
Yamada, K.7
Nagatsu, I.8
Matsumoto, S.9
Fujita, K.10
Nagatsu, T.11
-
75
-
-
0030590255
-
Decrease in exploratory behavior in naturally occurring cholecystokinin (CCK)-A receptor gene knockout rats
-
KOBAYASHI, S., M. OHTA, K. MIYASAKA, AND A. FUNAKOSHI. Decrease in exploratory behavior in naturally occurring cholecystokinin (CCK)-A receptor gene knockout rats. Neurosci. Lett. 214: 61-64, 1996.
-
(1996)
Neurosci. Lett.
, vol.214
, pp. 61-64
-
-
Kobayashi, S.1
Ohta, M.2
Miyasaka, K.3
Funakoshi, A.4
-
76
-
-
0029061324
-
Cardiac function in mice overexpressing the beta-adrenergic receptor kinase or a beta ARK inhibitor
-
KOCH, W. J., H. A. ROCKMAN, P. SAMAMA, R. A. HAMILTON, R. A. BOND, C. A. MILANO, AND R. J. LEFKOWITZ. Cardiac function in mice overexpressing the beta-adrenergic receptor kinase or a beta ARK inhibitor. Science 268: 1350-1353, 1995.
-
(1995)
Science
, vol.268
, pp. 1350-1353
-
-
Koch, W.J.1
Rockman, H.A.2
Samama, P.3
Hamilton, R.A.4
Bond, R.A.5
Milano, C.A.6
Lefkowitz, R.J.7
-
77
-
-
0030042726
-
Overexpression of an Agouti cDNA in the skin of transgenic mice recapitulates dominant coat color phenotypes of spontaneous mutants
-
KUCERA, G. T., D. M. BORTNER, AND M. P. ROSENBERG. Overexpression of an Agouti cDNA in the skin of transgenic mice recapitulates dominant coat color phenotypes of spontaneous mutants. Dev. Biol. 173: 162-173, 1996.
-
(1996)
Dev. Biol.
, vol.173
, pp. 162-173
-
-
Kucera, G.T.1
Bortner, D.M.2
Rosenberg, M.P.3
-
78
-
-
0029155706
-
Inducible gene targeting in mice
-
KUHN, R., F. SCHWENK, M. AGUET, AND K. RAJEWSKY. Inducible gene targeting in mice. Science 269: 1427-1429, 1995.
-
(1995)
Science
, vol.269
, pp. 1427-1429
-
-
Kuhn, R.1
Schwenk, F.2
Aguet, M.3
Rajewsky, K.4
-
79
-
-
0028360062
-
Elevated blood pressure and craniofacial abnormalities in mice deficient in endothelin-1
-
KURIHARA, Y., H. KURIHARA, H. SUZUKI, T. KODAMA, K. MAEMURA, R. NAGAI, H. ODA, T. KUWAKI, W. H. CAO, N. KAMADA, K. JISHAGE, K. OUCHI, Y. AZUMA, Y. TOYODA, T. ISHIKAWA, M. KUMADA, AND Y. YAZAKI. Elevated blood pressure and craniofacial abnormalities in mice deficient in endothelin-1. Nature 368: 703-710, 1994.
-
(1994)
Nature
, vol.368
, pp. 703-710
-
-
Kurihara, Y.1
Kurihara, H.2
Suzuki, H.3
Kodama, T.4
Maemura, K.5
Nagai, R.6
Oda, H.7
Kuwaki, T.8
Cao, W.H.9
Kamada, N.10
Jishage, K.11
Ouchi, K.12
Azuma, Y.13
Toyoda, Y.14
Ishikawa, T.15
Kumada, M.16
Yazaki, Y.17
-
80
-
-
0028981589
-
1 vasopressin receptor antisense oligodeoxynucleotide into septum reduces vasopressin binding, social discrimination abilities, and anxiety-related behavior in rats
-
1 vasopressin receptor antisense oligodeoxynucleotide into septum reduces vasopressin binding, social discrimination abilities, and anxiety-related behavior in rats. J. Neurosci. 15: 4250-4258, 1995.
-
(1995)
J. Neurosci.
, vol.15
, pp. 4250-4258
-
-
Landgraf, R.1
Gerstberger, R.2
Montkowski, A.3
Probst, J.C.4
Wotjak, C.T.5
Holsboer, F.6
Engelmann, M.7
-
82
-
-
0029852361
-
Gene modification via "plug and socket" gene targeting
-
LEWIS, J., B. YANG, P. DETLOFF, AND O. SMITHIES. Gene modification via "plug and socket" gene targeting. J. Clin. Invest. 97: 3-5, 1996.
-
(1996)
J. Clin. Invest.
, vol.97
, pp. 3-5
-
-
Lewis, J.1
Yang, B.2
Detloff, P.3
Smithies, O.4
-
83
-
-
0028947938
-
Constitutive activation of phototransduction by K296E opsin is not a cause of photoreceptor degeneration
-
LI, T., W. K. FRANSON, J. W. GORDON, E, L. BERSON, AND T. P. DRYJA. Constitutive activation of phototransduction by K296E opsin is not a cause of photoreceptor degeneration. Proc. Natl. Acad. Sei. USA 92: 3551-3555, 1995.
-
(1995)
Proc. Natl. Acad. Sei. USA
, vol.92
, pp. 3551-3555
-
-
Li, T.1
Franson, W.K.2
Gordon, J.W.3
Berson, E.L.4
Dryja, T.P.5
-
84
-
-
84993914892
-
Lesion versus lumen
-
LJBBY, P. Lesion versus lumen. Nat. Med. 1: 17-18, 1995.
-
(1995)
Nat. Med.
, vol.1
, pp. 17-18
-
-
Ljbby, P.1
-
85
-
-
0028973118
-
Chronic infusion of a CRH1 receptor antisense oligodeoxynucleotide into the central nucleus of the amygdala reduced anxiety-related behavior in socially defeated rats
-
LIEBSCH, G., R. LANDGRAF, R. GERSTBERGER, J. C. PROBST, C. T. WOTJAK, M. ENGELMANN, F. HOLSBOER, AND A. MONTKOWSKI. Chronic infusion of a CRH1 receptor antisense oligodeoxynucleotide into the central nucleus of the amygdala reduced anxiety-related behavior in socially defeated rats. Regul Pept, 59: 229-239, 1995.
-
(1995)
Regul Pept
, vol.59
, pp. 229-239
-
-
Liebsch, G.1
Landgraf, R.2
Gerstberger, R.3
Probst, J.C.4
Wotjak, C.T.5
Engelmann, M.6
Holsboer, F.7
Montkowski, A.8
-
86
-
-
0028823937
-
Regulation of the endothelin system in transgenic rats expressing the human endothelin-2 gene
-
UEFELDT, L., W. BOCKER, G. SCHONFELDER, M. ZINTZ, AND M. PAUL. Regulation of the endothelin system in transgenic rats expressing the human endothelin-2 gene. J. Cardiovasc. Pharmacol. 26, Suppl. 3: S32-S33, 1995.
-
(1995)
J. Cardiovasc. Pharmacol.
, vol.26
, Issue.3 SUPPL.
-
-
Uefeldt, L.1
Bocker, W.2
Schonfelder, G.3
Zintz, M.4
Paul, M.5
-
87
-
-
0029739504
-
2-adrenergic receptor subtypes b and c
-
2-adrenergic receptor subtypes b and c. Science 273: 803-805, 1996.
-
(1996)
Science
, vol.273
, pp. 803-805
-
-
Link, R.E.1
Desai, K.2
Hein, L.3
Stevens, M.E.4
Chruscinski, A.5
Bernstein, D.6
Barsh, G.S.7
Kobilka, B.K.8
-
89
-
-
0029833911
-
Antisense to NPY-Y1 demonstrates that Y1 receptors in the hypothalamus underlie NPY hypothermia and feeding in rats
-
LOPEZ, V. F., J. W. NYCE, B. T. GRIFFIN, J. C. ICE, AND R. D. MYERS. Antisense to NPY-Y1 demonstrates that Y1 receptors in the hypothalamus underlie NPY hypothermia and feeding in rats. Proc. R. Soc. Lond. B Biol. Sci. 263: 881-886, 1996.
-
(1996)
Proc. R. Soc. Lond. B Biol. Sci.
, vol.263
, pp. 881-886
-
-
Lopez, V.F.1
Nyce, J.W.2
Griffin, B.T.3
Ice, J.C.4
Myers, R.D.5
-
91
-
-
16044368159
-
1-adrenoceptors
-
Heart Circ. Physiol. 39
-
1-adrenoceptors. Am. J. Physiol. 270 (Heart Circ. Physiol. 39): H1465-H1472, 1996.
-
(1996)
Am. J. Physiol.
, vol.270
-
-
Mansier, P.1
Medigue, C.2
Charlotte, N.3
Vermeiren, C.4
Coraboeuf, E.5
Deroubai, E.6
Ratner, E.7
Chevalier, B.8
Clairambault, J.9
Carre, F.10
Dahkli, T.11
Bertin, B.12
Briand, P.13
Strosberg, D.14
Swynghedauw, B.15
-
92
-
-
0028937683
-
Specific deficit of the on response in visual transmission by targeted disruption of the mGluR6 gene
-
MASU, M., H. IWAKABE, Y. TAGAWA, T. MIYOSHI, M. YAMASHITA, Y. FUKUDA, H. SASAKI, K. HIROI, Y. NAKAMURA, R. SHIGEMOTO, M. TAKADA, K. NAKAMURA, K. NAKAO, M. KATSUM, AND S. NAKANISHI. Specific deficit of the ON response in visual transmission by targeted disruption of the mGluR6 gene. Cell 80: 757-765, 1995.
-
(1995)
Cell
, vol.80
, pp. 757-765
-
-
Masu, M.1
Iwakabe, H.2
Tagawa, Y.3
Miyoshi, T.4
Yamashita, M.5
Fukuda, Y.6
Sasaki, H.7
Hiroi, K.8
Nakamura, Y.9
Shigemoto, R.10
Takada, M.11
Nakamura, K.12
Nakao, K.13
Katsum, M.14
Nakanishi, S.15
-
93
-
-
0029970918
-
Chimeric mice carrying "regional" targeted deletion of the angiotensin type 1A receptor gene. Evidence against the role for local angiotensin in the in vivo feedback regulation of renin synthesis in juxtaglomerular cells
-
MATSUSAKA, T., H. NISHIMURA, H. UTSUNOMIYA, J. KAKUCHI, F. NIIMURA, T. INAGAMI, A. FOGO, AND I. ICHIKAWA. Chimeric mice carrying "regional" targeted deletion of the angiotensin type 1A receptor gene. Evidence against the role for local angiotensin in the in vivo feedback regulation of renin synthesis in juxtaglomerular cells. J. Clin. Invest. 98: 1867-1877, 1996.
-
(1996)
J. Clin. Invest.
, vol.98
, pp. 1867-1877
-
-
Matsusaka, T.1
Nishimura, H.2
Utsunomiya, H.3
Kakuchi, J.4
Niimura, F.5
Inagami, T.6
Fogo, A.7
Ichikawa, I.8
-
94
-
-
0029852678
-
Loss of morphine-induced analgesia, reward effect and withdrawal symptoms in mice lacking the mu-opioid-receptor gene
-
MATTHES, H. W., R. MALDONADO, F. SIMONIN, O. VALVERDE, S. SLOWE, I. KITCHEN, K. BEFORT, A. DIERICH, M. M. LE, P. DOLLE, E. TZAVARA, J. HANOUNE, B. P. ROQUES, AND B. L. KIEFFER. Loss of morphine-induced analgesia, reward effect and withdrawal symptoms in mice lacking the mu-opioid-receptor gene. Nature 383: 819-823, 1996.
-
(1996)
Nature
, vol.383
, pp. 819-823
-
-
Matthes, H.W.1
Maldonado, R.2
Simonin, F.3
Valverde, O.4
Slowe, S.5
Kitchen, I.6
Befort, K.7
Dierich, A.8
Le, M.M.9
Dolle, P.10
Tzavara, E.11
Hanoune, J.12
Roques, B.P.13
Kieffer, B.L.14
-
95
-
-
0028177565
-
Infusion of antisense oligodeoxynucleotides to the oxytocin receptor in the ventromedial hypothalamus reduces estrogeninduced sexual receptivity and oxytocin receptor binding in the female rat
-
MCCARTHY, M. M., S. P. KLEOPOULOS, C. V. MOBBS, AND D. W. PFAFF. Infusion of antisense oligodeoxynucleotides to the oxytocin receptor in the ventromedial hypothalamus reduces estrogeninduced sexual receptivity and oxytocin receptor binding in the female rat. Neuroendocrinology. 59: 432-440, 1994.
-
(1994)
Neuroendocrinology
, vol.59
, pp. 432-440
-
-
Mccarthy, M.M.1
Kleopoulos, S.P.2
Mobbs, C.V.3
Pfaff, D.W.4
-
96
-
-
0028263498
-
2-adrenergic receptor
-
2-adrenergic receptor. Science 264: 582-586, 1994.
-
(1994)
Science
, vol.264
, pp. 582-586
-
-
Milano, C.A.1
Allen, L.F.2
Rockman, H.A.3
Dolber, P.C.4
Mcminn, T.R.5
Chien, K.R.6
Johnson, T.D.7
Bond, R.A.8
Lefkowitz, R.J.9
-
97
-
-
0027940368
-
1B-adrenergic receptor in transgenic mice induces cardiac hypertrophy
-
1B-adrenergic receptor in transgenic mice induces cardiac hypertrophy. Proc. Natl. Acad. Sci. USA 91: 10109-10113, 1994.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 10109-10113
-
-
Milano, C.A.1
Dolber, P.C.2
Rockman, H.A.3
Bond, R.A.4
Venable, M.E.5
Allen, L.F.6
Lefkowitz, R.J.7
-
98
-
-
0028785081
-
Expression and transgenic studies of the mouse agouti gene provide insight into the mechanisms by which mammalian coat color patterns are generated
-
MILLAR, S. E., M. W. MILLER, M. E. STEVENS, AND G. S. BARSH. Expression and transgenic studies of the mouse agouti gene provide insight into the mechanisms by which mammalian coat color patterns are generated. Development 121: 3223-3232, 1995.
-
(1995)
Development
, vol.121
, pp. 3223-3232
-
-
Millar, S.E.1
Miller, M.W.2
Stevens, M.E.3
Barsh, G.S.4
-
99
-
-
0028196652
-
Orphan seven transmembrane domain receptors: Reversing pharmacology
-
MILLS, A., AND M. J. DUGGAN. Orphan seven transmembrane domain receptors: reversing pharmacology. Trends Biotechnol. 12: 47-49, 1994.
-
(1994)
Trends Biotechnol.
, vol.12
, pp. 47-49
-
-
Mills, A.1
Duggan, M.J.2
-
100
-
-
0029758145
-
2A adrenoceptor to be the subtype mediating the hypnotic response to the highly selective agonist, dexmedetomidine, in the locus coeruleus of the rat
-
2A adrenoceptor to be the subtype mediating the hypnotic response to the highly selective agonist, dexmedetomidine, in the locus coeruleus of the rat. J. Clin. Invest. 98: 1076-1080, 1996.
-
(1996)
J. Clin. Invest.
, vol.98
, pp. 1076-1080
-
-
Mizobe, T.1
Maghsoudi, K.2
Sitwala, K.3
Tianzhi, G.4
Ou, J.5
Maze, M.6
-
101
-
-
0030016488
-
Use of antisense oligodeoxynucleotide to determine delta-opioid receptor involvement in [D-Ala2]deltorphin Il-induced locomotor hyperactivity
-
MIZOGUCHI, H., M. NARITA, H. NAGASE, T. SUZUKI, R. M. QUOCK, AND L. F. TSENG. Use of antisense oligodeoxynucleotide to determine delta-opioid receptor involvement in [D-Ala2]deltorphin Il-induced locomotor hyperactivity. Life Sci. 59: PL69-PL73, 1996.
-
(1996)
Life Sci.
, vol.59
-
-
Mizoguchi, H.1
Narita, M.2
Nagase, H.3
Suzuki, T.4
Quock, R.M.5
Tseng, L.F.6
-
103
-
-
0027527714
-
Transgenesis in nonmurine species
-
MULLINS, J. J., AND L. J. MULLINS. Transgenesis in nonmurine species. Hypertension 22: 630-633, 1993.
-
(1993)
Hypertension
, vol.22
, pp. 630-633
-
-
Mullins, J.J.1
Mullins, L.J.2
-
104
-
-
0029981571
-
Transgenesis in the rat and larger mammals
-
MULLINS, L, J., AND J. J. MULLINS. Transgenesis in the rat and larger mammals. J. Clin. Invest. 97: 1557-1560, 1996.
-
(1996)
J. Clin. Invest.
, vol.97
, pp. 1557-1560
-
-
Mullins, L.J.1
Mullins, J.J.2
-
105
-
-
0027251934
-
Simulation of human autosomal dominant retinitis pigmentosa in transgenic mice expressing a mutated marine opsin gene
-
NAASH, M. I., J. G. HOLLYFIELD, U. M. AL, AND W. BAEHR. Simulation of human autosomal dominant retinitis pigmentosa in transgenic mice expressing a mutated marine opsin gene. Proc. Natl. Acad. Sci USA 90: 5499-5503, 1993.
-
(1993)
Proc. Natl. Acad. Sci USA
, vol.90
, pp. 5499-5503
-
-
Naash, M.I.1
Hollyfield, J.G.2
Al, U.M.3
Baehr, W.4
-
106
-
-
0029972409
-
Light-induced acceleration of photoreceptor degeneration in transgenic mice expressing mutant rhodopsin
-
NAASH, M. L, N. S. PEACHEY, Z. Y. LI, C. C. GRYCZAN, Y. GOTO, J. BLANKS, A. H. MILAM, AND H. RIPPS. Light-induced acceleration of photoreceptor degeneration in transgenic mice expressing mutant rhodopsin. Invest. Ophthalmol. Visual Sci. 37: 775-782, 1996.
-
(1996)
Invest. Ophthalmol. Visual Sci.
, vol.37
, pp. 775-782
-
-
Naash, M.L.1
Peachey, N.S.2
Li, Z.Y.3
Gryczan, C.C.4
Goto, Y.5
Blanks, J.6
Milam, A.H.7
Ripps, H.8
-
108
-
-
0029865151
-
Ecdysone-indudble gene expression in mammalian cells and transgenic mice
-
NO, D., T. P. YAO, AND R. M. EVANS. Ecdysone-indudble gene expression in mammalian cells and transgenic mice. Proc. Natl. Acad. Sci. USA 93: 3346-3351, 1996.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 3346-3351
-
-
No, D.1
Yao, T.P.2
Evans, R.M.3
-
109
-
-
0031025249
-
DNA antisense therapy for asthma in an animal model
-
NYCE, J. W., AND W. J. METZGER. DNA antisense therapy for asthma in an animal model. Nature 385: 721-725, 1997.
-
(1997)
Nature
, vol.385
, pp. 721-725
-
-
Nyce, J.W.1
Metzger, W.J.2
-
110
-
-
0026463972
-
Transgenic mice with a rhodopsin mutation (Pro23His): A mouse model of autosomal dominant retinitis pigmentosa
-
OLSSON, J. E., J. W. GORDON, B. S. PAWLYK, D. ROOF, A. HAYES, R. S. MOLDAY, S. MUKAI, G. S. COWLEY, E. L. BERSON, AND T. P. DRYJA. Transgenic mice with a rhodopsin mutation (Pro23His): a mouse model of autosomal dominant retinitis pigmentosa. Neuron 9: 815-830, 1992.
-
(1992)
Neuron
, vol.9
, pp. 815-830
-
-
Olsson, J.E.1
Gordon, J.W.2
Pawlyk, B.S.3
Roof, D.4
Hayes, A.5
Molday, R.S.6
Mukai, S.7
Cowley, G.S.8
Berson, E.L.9
Dryja, T.P.10
-
112
-
-
0027369421
-
Somatic mutations in the thyrotropin receptor gene cause hyperfunctioning thyroid adenomas
-
PARMA, J., L DUPREZ, S. J. VAN, P. COCHAUX, C. GERVY, J. MOCKEL, J. DUMONT, AND G. VASSART. Somatic mutations in the thyrotropin receptor gene cause hyperfunctioning thyroid adenomas. Nature 365: 649-651, 1993.
-
(1993)
Nature
, vol.365
, pp. 649-651
-
-
Parma, J.1
Duprez, L.2
Van, S.J.3
Cochaux, P.4
Gervy, C.5
Mockel, J.6
Dumont, J.7
Vassart, G.8
-
113
-
-
0029814483
-
Impaired cerebellar synaptic plasticity and motor performance in mice lacking the mGluR4 subtype of metabotropic glutamate receptor
-
PEKHLETSKI, R., R, GERLAI, L. S. OVERSTREET, X. P. HUANG, N. AGOPYAN, N. T. SLATER, N. W. ABRAMOW, J. C. RODER, AND D. R. HAMPSON, Impaired cerebellar synaptic plasticity and motor performance in mice lacking the mGluR4 subtype of metabotropic glutamate receptor. J. Neurosci, 16: 6364-6373, 1996.
-
(1996)
J. Neurosci
, vol.16
, pp. 6364-6373
-
-
Pekhletski, R.1
Gerlai, R.2
Overstreet, L.S.3
Huang, X.P.4
Agopyan, N.5
Slater, N.T.6
Abramow, N.W.7
Roder, J.C.8
Hampson, D.R.9
-
114
-
-
0027957662
-
Apoptotic photoreceptor cell death in mouse models of retinitis pig-mentosa
-
PORTERA, C. C., C. H. SUNG, J. NATHANS, AND R. ADLER. Apoptotic photoreceptor cell death in mouse models of retinitis pig-mentosa. Proc. Natl. Acad. Sci. USA 91: 974-978, 1994.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 974-978
-
-
Portera, C.C.1
Sung, C.H.2
Nathans, J.3
Adler, R.4
-
117
-
-
0026437138
-
Genetic mapping of two DNA markers, D16Ros1 and D16Ros2, flanking the mutation site in the chakragati mouse, a transgenic insertional mutant
-
RATTY, A. K., Y. MATSUDA, R. W. ELLIOTT, V. M. CHAPMAN, AND K. W. GROSS. Genetic mapping of two DNA markers, D16Ros1 and D16Ros2, flanking the mutation site in the chakragati mouse, a transgenic insertional mutant. Mamm. Genome 3: 5-10, 1992.
-
(1992)
Mamm. Genome
, vol.3
, pp. 5-10
-
-
Ratty, A.K.1
Matsuda, Y.2
Elliott, R.W.3
Chapman, V.M.4
Gross, K.W.5
-
118
-
-
0030015497
-
Targeted disruption of the mouse betal-adrenergic receptor gene: Developmental and cardiovascular effects
-
ROHRER, D. K., K. H. DESAI, J. R. JASPER, M. E. STEVENS, D. J. REGULA, G. S. BARSH, D. BERNSTEIN, AND B. K. KOBILKA. Targeted disruption of the mouse betal-adrenergic receptor gene: developmental and cardiovascular effects. Proc. Natl. Acad. Sci. USA 93: 7375-7380, 1996.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 7375-7380
-
-
Rohrer, D.K.1
Desai, K.H.2
Jasper, J.R.3
Stevens, M.E.4
Regula, D.J.5
Barsh, G.S.6
Bernstein, D.7
Kobilka, B.K.8
-
119
-
-
0028110523
-
Rhodopsin accumulation at abnormal sites in retinas of mice with a human P23H rhodopsin transgene
-
ROOF, D. J., M. ADAMIAN, AND A. HAYES. Rhodopsin accumulation at abnormal sites in retinas of mice with a human P23H rhodopsin transgene. Invest. Ophthalmol. Visual Sci. 35: 4049-4062, 1994.
-
(1994)
Invest. Ophthalmol. Visual Sci.
, vol.35
, pp. 4049-4062
-
-
Roof, D.J.1
Adamian, M.2
Hayes, A.3
-
120
-
-
0027984808
-
Endothelins: Molecular biology, biochemistry, pharmacology, physiology, and pathophysiology
-
RUBANYI, G. M., AND M. A. POLOKOFF. Endothelins: molecular biology, biochemistry, pharmacology, physiology, and pathophysiology. Pharmacol. Rev. 46: 325-415, 1994.
-
(1994)
Pharmacol. Rev.
, vol.46
, pp. 325-415
-
-
Rubanyi, G.M.1
Polokoff, M.A.2
-
122
-
-
0031015266
-
Genetic alteration of alpha-2C-adrenoceptor expression in mice: Influence on locomotor, hypothermie, and neurochemical effects of dexmedetomidine, a subtype-nonselective alpha-2-adrenoceptor agonist
-
SALLINEN, J., R. E. LINK, A. HAAPALINNA, T. VIITAMAA, M. KULATUNGA, B. SJOHOLM, E. MACDONALD, M. PELTO-HUIKKO, T. LEINO, G. S. BARSH, B. K. KOBILKA, AND M. SCHEININ. Genetic alteration of alpha-2C-adrenoceptor expression in mice: influence on locomotor, hypothermie, and neurochemical effects of dexmedetomidine, a subtype-nonselective alpha-2-adrenoceptor agonist Mol. Pharmacol. 51: 36-46, 1997.
-
(1997)
Mol. Pharmacol.
, vol.51
, pp. 36-46
-
-
Sallinen, J.1
Link, R.E.2
Haapalinna, A.3
Viitamaa, T.4
Kulatunga, M.5
Sjoholm, B.6
Macdonald, E.7
Pelto-Huikko, M.8
Leino, T.9
Barsh, G.S.10
Kobilka, B.K.11
Scheinin, M.12
-
123
-
-
0028132273
-
1B receptor
-
1B receptor. Science 265: 1875-1878, 1994.
-
(1994)
Science
, vol.265
, pp. 1875-1878
-
-
Saudou, F.1
Amara, D.A.2
Dierich, A.3
Lemeur, M.4
Ramboz, S.5
Segu, L.6
Buhot, M.C.7
Hen, R.8
-
124
-
-
0028989520
-
1A dopamine receptor gene promoter directs expression of a reporter gene to the central nervous system in transgenic mice
-
1A dopamine receptor gene promoter directs expression of a reporter gene to the central nervous system in transgenic mice. Brain Res.. 30: 336-346, 1995.
-
(1995)
Brain Res
, vol.30
, pp. 336-346
-
-
Severynse, D.M.1
Colapietro, A.M.2
Box, T.L.3
Caron, M.G.4
-
125
-
-
0029045856
-
Strain-dependent epithelial defects in mice lacking the EGP receptor
-
published erratum appears in Science 269: 909, 1995
-
SIBILIA, M., AND E. F. WAGNER. Strain-dependent epithelial defects in mice lacking the EGP receptor (published erratum appears in Science 269: 909, 1995). Science 269: 234-238, 1995.
-
(1995)
Science
, vol.269
, pp. 234-238
-
-
Sibilia, M.1
Wagner, E.F.2
-
126
-
-
0028834822
-
Viral vectors in gene therapy
-
SMITH, A. E. Viral vectors in gene therapy. Annu. Rev. Microbiol 49: 807-838, 1995.
-
(1995)
Annu. Rev. Microbiol
, vol.49
, pp. 807-838
-
-
Smith, A.E.1
-
127
-
-
0028221030
-
Magnetic resonance microscopy of mouse embryos
-
SMITH, B. R., G. A. JOHNSON, E. V. GROMAN, AND E. LINNEY. Magnetic resonance microscopy of mouse embryos. Proc. Natl. Acad. Sci. USA 91: 3530-3533, 1994.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 3530-3533
-
-
Smith, B.R.1
Johnson, G.A.2
Groman, E.V.3
Linney, E.4
-
128
-
-
0030298588
-
Antisense and ribozyme constructs in transgenic animals
-
SOKOL, D. L., AND J. D. MURRAY. Antisense and ribozyme constructs in transgenic animals. Transgenic Res. 5: 363-371, 1996.
-
(1996)
Transgenic Res.
, vol.5
, pp. 363-371
-
-
Sokol, D.L.1
Murray, J.D.2
-
129
-
-
0031030042
-
Opiate receptor knockout mice define mu receptor roles in endogenous nociceptive responses and morphine-induced analgesia
-
SORA, I., N. TAKAHASHI, M. FUNADA, H. UJIKE, R. S. REVAY, D. M. DONOVAN, L. L. MINER, AND G. R. UHL. Opiate receptor knockout mice define mu receptor roles in endogenous nociceptive responses and morphine-induced analgesia, Proc. Natl. Acad. Sci. USA 94: 1544-1549, 1997.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 1544-1549
-
-
Sora, I.1
Takahashi, N.2
Funada, M.3
Ujike, H.4
Revay, R.S.5
Donovan, D.M.6
Miner, L.L.7
Uhl, G.R.8
-
130
-
-
0028158627
-
Use of double-replacement gene targeting to replace the murine alpha-lactalbumin gene with its human counterpart in embryonic stem cells and mice
-
STAGEY, A., A. SCHNIEKE, J. MCWHIR, J. COOPER, A. COLMAN, AND D. W. MELTON. Use of double-replacement gene targeting to replace the murine alpha-lactalbumin gene with its human counterpart in embryonic stem cells and mice. Mol. Cell. Biol 14: 1009-1016, 1994.
-
(1994)
Mol. Cell. Biol
, vol.14
, pp. 1009-1016
-
-
Stagey, A.1
Schnieke, A.2
Mcwhir, J.3
Cooper, J.4
Colman, A.5
Melton, D.W.6
-
131
-
-
0029032496
-
The family of G-protein-coupled receptors
-
STRADER, C. D., T. M. FONG, M. P. GRAZIANO, AND M. R. TOTA. The family of G-protein-coupled receptors. FASEB J. 9: 745-754, 1995.
-
(1995)
FASEB J.
, vol.9
, pp. 745-754
-
-
Strader, C.D.1
Fong, T.M.2
Graziano, M.P.3
Tota, M.R.4
-
132
-
-
0029095684
-
Angiotensin II type 1A receptor-deficient mice with hypotension and hyperreninemia
-
SUGAYA, T., S. NISHIMATSU, K. TANIMOTO, E. TAKIMOTO, T. YAMAGISHI, K. IMAMURA, S. GOTO, K. IMAIZUMI, Y. HISADA, A. OTSUKA, H. UCHIDA, M. SUGIURA, K. FUKUTA, A. FUKAMIZU, AND K. MURAKAMI. Angiotensin II type 1A receptor-deficient mice with hypotension and hyperreninemia. J. Biol Chem. 270: 18719-18722, 1995.
-
(1995)
J. Biol Chem.
, vol.270
, pp. 18719-18722
-
-
Sugaya, T.1
Nishimatsu, S.2
Tanimoto, K.3
Takimoto, E.4
Yamagishi, T.5
Imamura, K.6
Goto, S.7
Imaizumi, K.8
Hisada, Y.9
Otsuka, A.10
Uchida, H.11
Sugiura, M.12
Fukuta, K.13
Fukamizu, A.14
Murakami, K.15
-
133
-
-
0029876304
-
Effects of phosphorothioated neuropeptide Y Y1-receptor antisense oligodeoxynucleotide in conscious rats and in human vessels
-
SUN, X. Y., X.H. ZHAO, D. ERLINGE, L. EDVINSSON, B. FALLGREN, C. WAHLESTEDT, AND T. HEDNER. Effects of phosphorothioated neuropeptide Y Y1-receptor antisense oligodeoxynucleotide in conscious rats and in human vessels. Br. J. Phannacol 118: 131-136, 1996.
-
(1996)
Br. J. Phannacol
, vol.118
, pp. 131-136
-
-
Sun, X.Y.1
Zhao, X.H.2
Erlinge, D.3
Edvinsson, L.4
Fallgren, B.5
Wahlestedt, C.6
Hedner, T.7
-
134
-
-
0027935666
-
A rhodopsin gene mutation responsible for autosomal dominant retinitis pigmentosa results in a protein that is defective in localization to the photoreceptor outer segment
-
SUNG, C. H., C. MAKINO, D. BAYLOR, AND J. NATHANS. A rhodopsin gene mutation responsible for autosomal dominant retinitis pigmentosa results in a protein that is defective in localization to the photoreceptor outer segment. J. Neurosci. 14: 5818-5833, 1994.
-
(1994)
J. Neurosci.
, vol.14
, pp. 5818-5833
-
-
Sung, C.H.1
Makino, C.2
Baylor, D.3
Nathans, J.4
-
135
-
-
0028838836
-
3-adrenergic receptor gene
-
3-adrenergic receptor gene. J. Biol. Chem. 270: 29483-29492, 1995,
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 29483-29492
-
-
Susulic, V.S.1
Frederich, R.C.2
Lawitts, J.3
Tozzo, E.4
Kahn, B.B.5
Harper, M.E.6
Himms, H.J.7
Flier, J.S.8
Lowell, B.B.9
-
136
-
-
0028909857
-
2c serotonin receptors
-
2c serotonin receptors. Nature 374: 542-546, 1995.
-
(1995)
Nature
, vol.374
, pp. 542-546
-
-
Tecott, L.H.1
Sun, L.M.2
Akana, S.F.3
Strack, A.M.4
Lowenstein, D.H.5
Dallman, M.F.6
Julius, D.7
-
137
-
-
0028935117
-
Noradrenaline is essential for mouse fetal development
-
THOMAS, S. A., A. M. MATSUMOTO, AND R. D. PALMITER. Noradrenaline is essential for mouse fetal development. Nature 374: 643-646, 1995.
-
(1995)
Nature
, vol.374
, pp. 643-646
-
-
Thomas, S.A.1
Matsumoto, A.M.2
Palmiter, R.D.3
-
138
-
-
0029064203
-
Targeted disruption of mouse EGF receptor: Effect of genetic background on mutant phenotype
-
THREADGILL, D, W., A. A. DLUGOSZ, L. A. HANSEN, T. TENNENBAUM, U. LICHTI, D. YEE, C. LAMANTIA, T. MOURTON, K. HERRIIP, R. C. HARRIS, J. A. BARNARD, S. H. YUSPA, R. J. COFFEY, AND T. MAGNUSON. Targeted disruption of mouse EGF receptor: effect of genetic background on mutant phenotype. Science 269: 230-234, 1995.
-
(1995)
Science
, vol.269
, pp. 230-234
-
-
Threadgill, D.W.1
Dlugosz, A.A.2
Hansen, L.A.3
Tennenbaum, T.4
Lichti, U.5
Yee, D.6
Lamantia, C.7
Mourton, T.8
Herriip, K.9
Harris, R.C.10
Barnard, J.A.11
Yuspa, S.H.12
Coffey, R.J.13
Magnuson, T.14
-
139
-
-
0028053758
-
The 5′ flanking region of the serotonin 2 receptor gene directs brain specific expression in transgenic animals
-
TOTH, M., D. DING, AND T. SHENK. The 5′ flanking region of the serotonin 2 receptor gene directs brain specific expression in transgenic animals. Brain Res. 27: 315-319, 1994.
-
(1994)
Brain Res.
, vol.27
, pp. 315-319
-
-
Toth, M.1
Ding, D.2
Shenk, T.3
-
140
-
-
0027962922
-
Antisense oligodeoxynucleotlde to a delta-opioid receptor given intrathecally blocks icv administered beta-endorphin-induced antlnocieeption in the mouse
-
TSENG, L. F., AND K. A. COLLINS. Antisense oligodeoxynucleotlde to a delta-opioid receptor given intrathecally blocks icv administered beta-endorphin-induced antlnocieeption in the mouse. Life Sci. 55: PL127-PL131, 1994.
-
(1994)
Life Sci.
, vol.55
-
-
Tseng, L.F.1
Collins, K.A.2
-
141
-
-
0028178240
-
Antisense oligodeoxynucleotide to a delta-opioid receptor selectively blocks the spinal antinociception induced by delta-, but not mu- or kappaopioid receptor agonists in the mouse
-
TSENG, L. F., K. A. COLLINS, AND J. P. KAMPINE. Antisense oligodeoxynucleotide to a delta-opioid receptor selectively blocks the spinal antinociception induced by delta-, but not mu- or kappaopioid receptor agonists in the mouse. Eur. J. PharmacoL 258: R1-R3, 1994.
-
(1994)
Eur. J. PharmacoL
, vol.258
-
-
Tseng, L.F.1
Collins, K.A.2
Kampine, J.P.3
-
142
-
-
0030460425
-
Subregion- and cell type-restricted gene knockout in mouse brain
-
TSIEN, J. Z., D. F. CHEN, D. GERBER, C. TOM, E. MERCER, D. J. ANDERSON, M. MAYFORD, E. R. KANDEL, AND S. TONEGAWA. Subregion- and cell type-restricted gene knockout in mouse brain. Cell 87: 1315-1326, 1996.
-
(1996)
Cell
, vol.87
, pp. 1315-1326
-
-
Tsien, J.Z.1
Chen, D.F.2
Gerber, D.3
Tom, C.4
Mercer, E.5
Anderson, D.J.6
Mayford, M.7
Kandel, E.R.8
Tonegawa, S.9
-
143
-
-
0030446363
-
The essential role of hippocampal CA1 NMDA receptor-dependent synaptic plasticity in spatial memory
-
TSIEN, J. Z., P. T. HUERTA, AND S. TONEGAWA. The essential role of hippocampal CA1 NMDA receptor-dependent synaptic plasticity in spatial memory. Cell 87: 1327-1338, 1996.
-
(1996)
Cell
, vol.87
, pp. 1327-1338
-
-
Tsien, J.Z.1
Huerta, P.T.2
Tonegawa, S.3
-
145
-
-
0030463433
-
Mitogenic signalling via G protein-coupled receptors
-
VAN BIESEN, T., L. M. LUTTRELL, B. E, HAWES, AND R. J. LEFKOWITZ. Mitogenic signalling via G protein-coupled receptors. Endocr. Rev. 17: 698-714, 1996.
-
(1996)
Endocr. Rev.
, vol.17
, pp. 698-714
-
-
Van Biesen, T.1
Luttrell, L.M.2
Hawes, B.E.3
Lefkowitz, R.J.4
-
146
-
-
0010498843
-
Efficient insertion of genes into the mouse germ line via retroviral vectors
-
VAN DER PUTTEN, H., F. M. BOTTERI, A. D. MILLER, M. G. ROSENFELD, H. FAN, R. M. EVANS, AND I. M. VERMA. Efficient insertion of genes into the mouse germ line via retroviral vectors. Proc. Natl. Acad. Sci. USA 82: 6148-6152, 1985.
-
(1985)
Proc. Natl. Acad. Sci. USA
, vol.82
, pp. 6148-6152
-
-
Van Der Putten, H.1
Botteri, F.M.2
Miller, A.D.3
Rosenfeld, M.G.4
Fan, H.5
Evans, R.M.6
Verma, I.M.7
-
148
-
-
0028603394
-
Creatine kinase (CK) in skeletal muscle energy metabolism: A study of mouse mutants with graded reduction in muscle CK expression
-
VAN DEURSEN, J., W. RUITENBEEK, A. HEERSCHAP, P. JAP, L. H. TER, AND B. WIERINGA. Creatine kinase (CK) in skeletal muscle energy metabolism: a study of mouse mutants with graded reduction in muscle CK expression. Proc. Natl. Acad. Sci. USA 91: 9091-9095, 1994.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 9091-9095
-
-
Van Deursen, J.1
Ruitenbeek, W.2
Heerschap, A.3
Jap, P.4
Ter, L.H.5
Wieringa, B.6
-
149
-
-
17544403138
-
Approaching the multifaceted nature of energy metabolism: Inactivation of the cytosolic creatine kinases via homologous recombination in mouse embryonic stem cells
-
VAN DEURSEN, J., AND B. WIERINGA. Approaching the multifaceted nature of energy metabolism: inactivation of the cytosolic creatine kinases via homologous recombination in mouse embryonic stem cells. Mol Cell Biochem. 134: 263-274, 1994.
-
(1994)
Mol Cell Biochem.
, vol.134
, pp. 263-274
-
-
Van Deursen, J.1
Wieringa, B.2
-
151
-
-
0028820032
-
Altered cAMP levels in retinas from transgenic mice expressing a rhodopsin mutant
-
WEISS, E. R., Y. HAO, C. D. DICKERSON, S. OSAWA, W. SHI, L. ZHANG, AND F. WONG. Altered cAMP levels in retinas from transgenic mice expressing a rhodopsin mutant. Biochem. Biophys. Res. Commun. 216: 755-761, 1995.
-
(1995)
Biochem. Biophys. Res. Commun.
, vol.216
, pp. 755-761
-
-
Weiss, E.R.1
Hao, Y.2
Dickerson, C.D.3
Osawa, S.4
Shi, W.5
Zhang, L.6
Wong, F.7
-
152
-
-
0028948661
-
Structure and function of ASP, the human homolog of the mouse agouti gene
-
WILSON, B. D., M. M. OLLMANN, L. KANG, M. STOFFEL, G. I. BELL, AND G. S. BARSH. Structure and function of ASP, the human homolog of the mouse agouti gene. Hum. Mol. Genet. 4: 223-230, 1995.
-
(1995)
Hum. Mol. Genet.
, vol.4
, pp. 223-230
-
-
Wilson, B.D.1
Ollmann, M.M.2
Kang, L.3
Stoffel, M.4
Bell, G.I.5
Barsh, G.S.6
-
153
-
-
0030563195
-
Adenoviruses as gene-delivery vehicles
-
WILSON, J. M. Adenoviruses as gene-delivery vehicles. N. Engl. J. Med. 334: 1185-1187, 1996.
-
(1996)
N. Engl. J. Med.
, vol.334
, pp. 1185-1187
-
-
Wilson, J.M.1
-
154
-
-
0025231388
-
Direct gene transfer into mouse muscle in vivo
-
WOLFF, J. A., R. W. MALONE, P. WILLIAMS, W. CHONG, G. ACSADI, A. JANI, AND P. L. FELGNER. Direct gene transfer into mouse muscle in vivo. Science 1465-1468, 1990.
-
(1990)
Science
, pp. 1465-1468
-
-
Wolff, J.A.1
Malone, R.W.2
Williams, P.3
Chong, W.4
Acsadi, G.5
Jani, A.6
Felgner, P.L.7
-
155
-
-
0028333746
-
Double replacement: Strategy for efficient introduction of subtle mutations into the murine Colla1 gene by homologous recombination in embryonic
-
WU, H., X. LIU, AND R. JAENISCH. Double replacement: strategy for efficient introduction of subtle mutations into the murine Colla1 gene by homologous recombination in embryonic stem cells. Proc. Natl. Acad. Sci. USA 91: 2819-2823, 1994.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 2819-2823
-
-
Wu, H.1
Liu, X.2
Jaenisch, R.3
-
156
-
-
0028987214
-
2-adrenoceptor to a pertussis toxin-sensitive G protein in cardiac myocytes
-
2-adrenoceptor to a pertussis toxin-sensitive G protein in cardiac myocytes. Mol. Pharmacol. 47: 322-329, 1995.
-
(1995)
Mol. Pharmacol.
, vol.47
, pp. 322-329
-
-
Xiao, R.P.1
Ji, X.2
Lakatta, E.G.3
-
157
-
-
0028605680
-
1 receptor mutant mice
-
1 receptor mutant mice. Cell 79: 945-955, 1994.
-
(1994)
Cell
, vol.79
, pp. 945-955
-
-
Xu, M.1
Hit, X.T.2
Cooper, D.C.3
Moratalla, R.4
Graybiel, A.M.5
White, F.J.6
Tonegawa, S.7
-
158
-
-
0027945523
-
1 receptor mutant mice are deficient in striatal expression of dynorhin and in ciopamine-mediated behavioral responses
-
1 receptor mutant mice are deficient in striatal expression of dynorhin and in ciopamine-mediated behavioral responses. Cell 79: 729-742, 1994.
-
(1994)
Cell
, vol.79
, pp. 729-742
-
-
Xu, M.1
Moratalla, R.2
Gold, L.H.3
Hiroi, N.4
Koob, G.F.5
Graybiel, A.M.6
Tonegawa, S.7
-
159
-
-
9344255435
-
Impairment of hippocanipal mossy fiber LTD in mice lacking muluR2
-
YOKOI, M., K. KOBAYASHI, T. MANABE, T. TAKAHASHI, I. SAKAGUCHI, G. KATSUURA, R. SHIGEMOTO, H. OHISHI, S. NOMURA, K. NAKAMURA, K. NAKAO, M. KATSUKI. AND S. NAKANISHI. Impairment of hippocanipal mossy fiber LTD in mice lacking muluR2. Science 273: 645-47. 1996.
-
(1996)
Science
, vol.273
, pp. 645-647
-
-
Yokoi, M.1
Kobayashi, K.2
Manabe, T.3
Takahashi, T.4
Sakaguchi, I.5
Katsuura, G.6
Shigemoto, R.7
Ohishi, H.8
Nomura, S.9
Nakamura, K.10
Nakao, K.11
Katsuki, M.12
Nakanishi, S.13
-
160
-
-
0027158027
-
Reversal of left-right asymmetry: A situs inversus mutation
-
YOKOYAMA, T., N. G. COPELAND, N. A. JENKINS, C. A. MONTGOMERY, F. F. ELDER, AND P. A. OVERBEEK. Reversal of left-right asymmetry: a situs inversus mutation. Science 260: 679-682, 1993.
-
(1993)
Science
, vol.260
, pp. 679-682
-
-
Yokoyama, T.1
Copeland, N.G.2
Jenkins, N.A.3
Montgomery, C.A.4
Elder, F.F.5
Overbeek, P.A.6
-
161
-
-
0027956203
-
Reduction in muscarinic receptors by antisense oligodeoxynucleotide
-
ZANG, Z., W. FLORIJN, AND I. CREESE. Reduction in muscarinic receptors by antisense oligodeoxynucleotide. Biochem. Pharrnacol 48: 225-228, 1994.
-
(1994)
Biochem. Pharrnacol
, vol.48
, pp. 225-228
-
-
Zang, Z.1
Florijn, W.2
Creese, I.3
-
162
-
-
0027490804
-
2 receptors: Behavioral correlates
-
2 receptors: behavioral correlates. Neurosci. Lett. 161: 223-226, 1993.
-
(1993)
Neurosci. Lett.
, vol.161
, pp. 223-226
-
-
Zhang, M.1
Creese, I.2
-
163
-
-
0028170936
-
1 dopamine receptor-mediated behaviors in normal mice and in mice lesioned with 6-hydroxydopamine
-
1 dopamine receptor-mediated behaviors in normal mice and in mice lesioned with 6-hydroxydopamine. J. Pharmacol. Exp. Ther. 271: 1462-1470, 1994.
-
(1994)
J. Pharmacol. Exp. Ther.
, vol.271
, pp. 1462-1470
-
-
Zhang, S.P.1
Zhou, L.W.2
Weiss, B.3
-
164
-
-
0029962975
-
Inducible site-directed recombination in mouse embryonic stem cells
-
ZHANG, Y., C. RIESTERER, A. M. AYRALL, F. SABUTZKY, T. D. LITTLEWOOD, AND M. RETH. Inducible site-directed recombination in mouse embryonic stem cells. Nucleic Adds Res. 24: 543-548, 1996.
-
(1996)
Nucleic Adds Res.
, vol.24
, pp. 543-548
-
-
Zhang, Y.1
Riesterer, C.2
Ayrall, A.M.3
Sabutzky, F.4
Littlewood, T.D.5
Reth, M.6
-
166
-
-
0029588435
-
Dopamine-deflcient mice are severely hypoactive, adipsic, and aphagic
-
ZHOU, Q. Y., AND R. D. PALMITER. Dopamine-deflcient mice are severely hypoactive, adipsic, and aphagic. Cell 83: 1197-1209, 1995.
-
(1995)
Cell
, vol.83
, pp. 1197-1209
-
-
Zhou, Q.Y.1
Palmiter, R.D.2
-
167
-
-
0028912476
-
Targeted disruption of the tyrosine hydroxylase gene reveals that catecholamines are required for mouse fetal development
-
ZHOU, Q. Y., C. J. QUAIFE, AND R. D. PALMITER, Targeted disruption of the tyrosine hydroxylase gene reveals that catecholamines are required for mouse fetal development. Nature 374: 640-643, 1995.
-
(1995)
Nature
, vol.374
, pp. 640-643
-
-
Zhou, Q.Y.1
Quaife, C.J.2
Palmiter, R.D.3
-
168
-
-
0029588560
-
Antisense phosphorothioate oligodeoxynucleotides: Introductory concepts and possible molecular mechanisms of toxicity
-
ZON, G. Antisense phosphorothioate oligodeoxynucleotides: introductory concepts and possible molecular mechanisms of toxicity. Toxicol. Lett. 83: 419-424, 1995.
-
(1995)
Toxicol. Lett.
, vol.83
, pp. 419-424
-
-
Zon, G.1
|