-
2
-
-
0040668827
-
An oligomer complementary to c-myb encoded mRNA inhibits proliferation of human myeloid leukemia cell lines
-
Anfossi, G., Gewirtz, A. and Calabretta, B. (1989) An oligomer complementary to c-myb encoded mRNA inhibits proliferation of human myeloid leukemia cell lines. Proc. Natl Acad. Sci. USA 86, 3379-83.
-
(1989)
Proc. Natl Acad. Sci. USA
, vol.86
, pp. 3379-3383
-
-
Anfossi, G.1
Gewirtz, A.2
Calabretta, B.3
-
3
-
-
0026675078
-
Antisense probes targeted to an internal domain in U2 snRNP specifically inhibit the second step of pre-mRNA splicing
-
Barabino, S., Sproat, B. and Lamond, A. (1992) Antisense probes targeted to an internal domain in U2 snRNP specifically inhibit the second step of pre-mRNA splicing. Nucl. Acids Res. 20, 4457-64.
-
(1992)
Nucl. Acids Res.
, vol.20
, pp. 4457-4464
-
-
Barabino, S.1
Sproat, B.2
Lamond, A.3
-
4
-
-
0026134483
-
Visualization of RNA transcription and processing
-
Beyer, A. and Osheim, Y. (1991) Visualization of RNA transcription and processing. Seminars Cell Biol. 2, 131-40.
-
(1991)
Seminars Cell Biol.
, vol.2
, pp. 131-140
-
-
Beyer, A.1
Osheim, Y.2
-
5
-
-
0025199669
-
Mechanisms of mRNA decay
-
Brawerman, G. (1990) Mechanisms of mRNA decay. Trends Biotech. 8, 171-4.
-
(1990)
Trends Biotech.
, vol.8
, pp. 171-174
-
-
Brawerman, G.1
-
6
-
-
0026089494
-
Normal and leukemia hematopoietic cells manifest differential sensitivity to inhibitory effects of c-myb antisense oligodeoxynucleotides: An in vitro study relevant to bone marrow purging
-
Calabretta, B., Sims, R., Valtieri, M., Caracciolo, D., Szczylik, C., Venturelli, D., Ratajczak, M., Beran, M. and Gewirtz, A. (1991) Normal and leukemia hematopoietic cells manifest differential sensitivity to inhibitory effects of c-myb antisense oligodeoxynucleotides: an in vitro study relevant to bone marrow purging. Proc. Natl Acad. Sci. USA 88, 2351-5.
-
(1991)
Proc. Natl Acad. Sci. USA
, vol.88
, pp. 2351-2355
-
-
Calabretta, B.1
Sims, R.2
Valtieri, M.3
Caracciolo, D.4
Szczylik, C.5
Venturelli, D.6
Ratajczak, M.7
Beran, M.8
Gewirtz, A.9
-
7
-
-
0024357988
-
Specific gene suppression by engineered ribozymes in monkey cells
-
Cameron, F. and Jennings, P. (1989) Specific gene suppression by engineered ribozymes in monkey cells. Proc. Natl Acad. Sci. USA 86, 9139-43.
-
(1989)
Proc. Natl Acad. Sci. USA
, vol.86
, pp. 9139-9143
-
-
Cameron, F.1
Jennings, P.2
-
8
-
-
0025459760
-
Organ-specific modulation of gene expression in transgenic plants using antisense RNA
-
Cannon, M., Platz, J., Leary, M., Kokdeo, C. and Cannon, F. (1990) Organ-specific modulation of gene expression in transgenic plants using antisense RNA. Plant Mol. Biol. 15, 39-47.
-
(1990)
Plant Mol. Biol.
, vol.15
, pp. 39-47
-
-
Cannon, M.1
Platz, J.2
Leary, M.3
Kokdeo, C.4
Cannon, F.5
-
9
-
-
0024819020
-
Iron regulation of transferrin receptor mRNA levels requires iron-responsive elements and a rapid turnover determinant in the 3′ untranslated region of the mRNA
-
Casey, J., Koeller, D., Ramin, V., Klausner, R. and Harford, J. (1989) Iron regulation of transferrin receptor mRNA levels requires iron-responsive elements and a rapid turnover determinant in the 3′ untranslated region of the mRNA. EMBO J. 8, 3693-9.
-
(1989)
EMBO J.
, vol.8
, pp. 3693-3699
-
-
Casey, J.1
Koeller, D.2
Ramin, V.3
Klausner, R.4
Harford, J.5
-
10
-
-
0027048414
-
Biological and functional aspects of catalytic RNAs
-
Castanotto, D., Rossi, J. and Deshler, J. (1992) Biological and functional aspects of catalytic RNAs. Crit. Rev. Euk. Gene Exp. 2, 331-57.
-
(1992)
Crit. Rev. Euk. Gene Exp.
, vol.2
, pp. 331-357
-
-
Castanotto, D.1
Rossi, J.2
Deshler, J.3
-
11
-
-
0026779558
-
Multitarget-ribozyme directed to cleave at up to nine highly conserved HIV-1 env RNA regions inhibits HIV-1 replication-potential effectiveness against most presently sequenced HIV-1 isolates
-
Chen, C., Banerjea, A., Harmison, G., Haglaund, K. and Schubert, M. (1992) Multitarget-ribozyme directed to cleave at up to nine highly conserved HIV-1 env RNA regions inhibits HIV-1 replication-potential effectiveness against most presently sequenced HIV-1 isolates. Nucl. Acids Res. 20, 4581-9.
-
(1992)
Nucl. Acids Res.
, vol.20
, pp. 4581-4589
-
-
Chen, C.1
Banerjea, A.2
Harmison, G.3
Haglaund, K.4
Schubert, M.5
-
12
-
-
0026052924
-
Antisense oligonucleotides inhibit intercellular adhesion Molecule 1 expression by two distinct mechanisms
-
Chiang, M., Chan, H., Zounes, M., Freier, S., Lima, W. and Bennett, C. (1991) Antisense oligonucleotides inhibit intercellular adhesion Molecule 1 expression by two distinct mechanisms. J. Biol. Chem. 206, 18162-71.
-
(1991)
J. Biol. Chem.
, vol.206
, pp. 18162-18171
-
-
Chiang, M.1
Chan, H.2
Zounes, M.3
Freier, S.4
Lima, W.5
Bennett, C.6
-
13
-
-
0024791135
-
Antisense RNA complementary to 3′ coding and noncoding sequences of creatine kinase is a potent inhibitor of translation in vivo
-
Ch'ng, J., Mulligan, R., Schimmel, P. and Holmes, E. (1989) Antisense RNA complementary to 3′ coding and noncoding sequences of creatine kinase is a potent inhibitor of translation in vivo. Proc. Natl Acad. Sci. USA 86, 10006-12.
-
(1989)
Proc. Natl Acad. Sci. USA
, vol.86
, pp. 10006-10012
-
-
Ch'ng, J.1
Mulligan, R.2
Schimmel, P.3
Holmes, E.4
-
14
-
-
0027473887
-
Ionic requirements for RNA binding, cleavage, and ligation by the hairpin ribozyme
-
Chowrira, B., Berzal-Herranz, A. and Burke, J. (1993) Ionic requirements for RNA binding, cleavage, and ligation by the hairpin ribozyme. Biochem. 32, 1088-95.
-
(1993)
Biochem.
, vol.32
, pp. 1088-1095
-
-
Chowrira, B.1
Berzal-Herranz, A.2
Burke, J.3
-
15
-
-
0028006824
-
Transgenic mice expressing antisense interleukin-3 RNA develop a B-cell lymphoproliferative syndrome or neurologic dysfunction
-
Cockayne, D., Bodine, D., Cline, A., Nienhaus, A. and Dunbar, C. (1994) Transgenic mice expressing antisense interleukin-3 RNA develop a B-cell lymphoproliferative syndrome or neurologic dysfunction. Blood 84, 2699-710.
-
(1994)
Blood
, vol.84
, pp. 2699-2710
-
-
Cockayne, D.1
Bodine, D.2
Cline, A.3
Nienhaus, A.4
Dunbar, C.5
-
16
-
-
0024978532
-
Nuclear and cytoplasmic sites for antisense control
-
Cornelissen, M. (1989) Nuclear and cytoplasmic sites for antisense control. Nucl. Acids Res. 17, 7203-9.
-
(1989)
Nucl. Acids Res.
, vol.17
, pp. 7203-7209
-
-
Cornelissen, M.1
-
17
-
-
0025199668
-
The in vivo application of ribozymes
-
Cotten, M. (1990) The in vivo application of ribozymes. Trends Biotech. 8, 174-8.
-
(1990)
Trends Biotech.
, vol.8
, pp. 174-178
-
-
Cotten, M.1
-
18
-
-
0022313127
-
Phenocopy of Discoiden 1-minus mutants by antisense transformation in Dictyostelium
-
Crowley, T., Nellen, W., Gomer, R. and Firtel, R. (1985) Phenocopy of Discoiden 1-minus mutants by antisense transformation in Dictyostelium. Cell 43, 633-41.
-
(1985)
Cell
, vol.43
, pp. 633-641
-
-
Crowley, T.1
Nellen, W.2
Gomer, R.3
Firtel, R.4
-
19
-
-
0027381517
-
Altered expression of nerve growth factor in the skin of transgenic mice leads to changes in response to mechanical stimuli
-
Davis, B., Lewin, G., Mendell, L., Jones, M. and Albers, K. (1993) Altered expression of nerve growth factor in the skin of transgenic mice leads to changes in response to mechanical stimuli. Neuroscience 56, 789-92.
-
(1993)
Neuroscience
, vol.56
, pp. 789-792
-
-
Davis, B.1
Lewin, G.2
Mendell, L.3
Jones, M.4
Albers, K.5
-
20
-
-
0028295284
-
Ribozyme-mediated attenuation of pancreatic β-cell glucokinase expression in transgenic mice results in impaired glucose-induced insulin secretion
-
Efrat, S., Lieser, M., Wu, Y., Fusco-DeMane, D., Emran, O., Surana, M., Jetton, T., Magnuson, M., Weir, G. and Fleischer, N. (1994) Ribozyme-mediated attenuation of pancreatic β-cell glucokinase expression in transgenic mice results in impaired glucose-induced insulin secretion. Proc. Natl Acad. Sci. USA 91, 2051-5.
-
(1994)
Proc. Natl Acad. Sci. USA
, vol.91
, pp. 2051-2055
-
-
Efrat, S.1
Lieser, M.2
Wu, Y.3
Fusco-DeMane, D.4
Emran, O.5
Surana, M.6
Jetton, T.7
Magnuson, M.8
Weir, G.9
Fleischer, N.10
-
21
-
-
0027430291
-
Creating a conditional mutation of Wnt-1 by antisense transgenesis provides evidence that Wnt-1 is not essential for spermatogenesis
-
Erickson, R.P., Lai, L.W. and Grimes, J. (1993) Creating a conditional mutation of Wnt-1 by antisense transgenesis provides evidence that Wnt-1 is not essential for spermatogenesis. Devel. Biol 14, 274-81.
-
(1993)
Devel. Biol
, vol.14
, pp. 274-281
-
-
Erickson, R.P.1
Lai, L.W.2
Grimes, J.3
-
22
-
-
0025265468
-
Substrate sequence effects on "hammerhead" RNA catalytic efficiency
-
Fedor, M. and Uhlenbeck, O. (1990) Substrate sequence effects on "hammerhead" RNA catalytic efficiency. Proc. Natl Acad. Sci. USA 87, 1668-72.
-
(1990)
Proc. Natl Acad. Sci. USA
, vol.87
, pp. 1668-1672
-
-
Fedor, M.1
Uhlenbeck, O.2
-
23
-
-
0023643095
-
Self-cleavage of virusoid RNA is performed by the proposed 55-nucleotide active site
-
Forster, A. and Symons, R. (1987a) Self-cleavage of virusoid RNA is performed by the proposed 55-nucleotide active site. Cell 50, 9-16.
-
(1987)
Cell
, vol.50
, pp. 9-16
-
-
Forster, A.1
Symons, R.2
-
24
-
-
0023663396
-
Self-cleavage of plus and minus RNAs of a virusoid and a structural model for the active sites
-
Forster, A. and Symons, R. (1987b) Self-cleavage of plus and minus RNAs of a virusoid and a structural model for the active sites. Cell 49, 211-20.
-
(1987)
Cell
, vol.49
, pp. 211-220
-
-
Forster, A.1
Symons, R.2
-
25
-
-
0017351102
-
5′ terminal structure and mRNA stability
-
Furuichi, Y., LaFiandra, A. and Shatkin, A. (1977) 5′ terminal structure and mRNA stability. Nature 266, 235-9.
-
(1977)
Nature
, vol.266
, pp. 235-239
-
-
Furuichi, Y.1
LaFiandra, A.2
Shatkin, A.3
-
26
-
-
0003799787
-
Inhibition of human immunodeficiency virus replication by antisense oligodeoxynucleotides
-
Goodchild, J., Agrawal, S., Civeira, M., Sarin, P., Sun, D. and Zamecnik, P. (1988) Inhibition of human immunodeficiency virus replication by antisense oligodeoxynucleotides. Proc. Natl Acad. Sci. USA 85, 5507-11.
-
(1988)
Proc. Natl Acad. Sci. USA
, vol.85
, pp. 5507-5511
-
-
Goodchild, J.1
Agrawal, S.2
Civeira, M.3
Sarin, P.4
Sun, D.5
Zamecnik, P.6
-
27
-
-
0022555863
-
The role of antisense RNA in gene regulation
-
Green, P., Pines, O. and Inouye, M. (1986) The role of antisense RNA in gene regulation. Ann. Rev. Biochem. 55, 569-97.
-
(1986)
Ann. Rev. Biochem.
, vol.55
, pp. 569-597
-
-
Green, P.1
Pines, O.2
Inouye, M.3
-
28
-
-
0024976556
-
Metal ion requirements for sequence-specific endoribonuclease activity of the Tetrahymena ribozyme
-
Grosshans, C. and Cech, T. (1989) Metal ion requirements for sequence-specific endoribonuclease activity of the Tetrahymena ribozyme. Biochem. 28, 6888-94.
-
(1989)
Biochem.
, vol.28
, pp. 6888-6894
-
-
Grosshans, C.1
Cech, T.2
-
29
-
-
0025876622
-
Inhibition of Moloney murine leukemia virus-induced leukemia in transgenic mice expressing antisense RNA complementary to the retroviral packaging sequences
-
Han, L., Yun, J.S. and Wagner, T.E. (1991) Inhibition of Moloney murine leukemia virus-induced leukemia in transgenic mice expressing antisense RNA complementary to the retroviral packaging sequences. Proc. Natl Acad. Sci. USA 88, 4313-7.
-
(1991)
Proc. Natl Acad. Sci. USA
, vol.88
, pp. 4313-4317
-
-
Han, L.1
Yun, J.S.2
Wagner, T.E.3
-
30
-
-
0027489464
-
Attentuation of white gene expression in transgenic Drosophila melanogaster: Possible role of catalytic antisense RNA
-
Heinrich, J.C., Tabler, M. and Louis, C. (1993) Attentuation of white gene expression in transgenic Drosophila melanogaster: Possible role of catalytic antisense RNA. Devel. Genet. 14, 258-65.
-
(1993)
Devel. Genet.
, vol.14
, pp. 258-265
-
-
Heinrich, J.C.1
Tabler, M.2
Louis, C.3
-
31
-
-
0025938440
-
Determinants and regulation of cytoplasmic mRNA stability in eukaryotic cells
-
Hentze, D. (1991) Determinants and regulation of cytoplasmic mRNA stability in eukaryotic cells. Biochem. Biophys. Acta 1090, 281-92.
-
(1991)
Biochem. Biophys. Acta
, vol.1090
, pp. 281-292
-
-
Hentze, D.1
-
32
-
-
0025085590
-
Catalysis of RNA cleavage by the Tetrahymena thermophila ribozyme. 1. Kinetic description of the reaction of an RNA substrate complementary to the active site
-
Herschlag, D. and Cech, T. (1990) Catalysis of RNA cleavage by the Tetrahymena thermophila ribozyme. 1. Kinetic description of the reaction of an RNA substrate complementary to the active site. Biochem. 29, 10159-71.
-
(1990)
Biochem.
, vol.29
, pp. 10159-10171
-
-
Herschlag, D.1
Cech, T.2
-
33
-
-
0026770382
-
Differential antisense transcription from the Dictyostelium EB4 gene locus: Implications on antisense-mediated regulation of mRNA stability
-
Hildebrandt, M. and Nellen, W. (1992) Differential antisense transcription from the Dictyostelium EB4 gene locus: Implications on antisense-mediated regulation of mRNA stability. Cell 69, 197-204.
-
(1992)
Cell
, vol.69
, pp. 197-204
-
-
Hildebrandt, M.1
Nellen, W.2
-
34
-
-
0027328396
-
Incorporation of the catalytic domain of a hammerhead ribozyme into antisense RNA enhances its inhibitory effect on the replication of human immunodeficiency virus type 1
-
Homann, M., Tzortzakaki, S., Rittner, K., Sczakiel, G. and Tabler, M. (1993) Incorporation of the catalytic domain of a hammerhead ribozyme into antisense RNA enhances its inhibitory effect on the replication of human immunodeficiency virus type 1. Nucl. Acids Res. 21, 2809-14.
-
(1993)
Nucl. Acids Res.
, vol.21
, pp. 2809-2814
-
-
Homann, M.1
Tzortzakaki, S.2
Rittner, K.3
Sczakiel, G.4
Tabler, M.5
-
35
-
-
0023047510
-
Self-cleavage of plus and minus RNA transcripts of avocada sunblotch viroid
-
Hutchins, C., Rathjen, P., Forster, A. and Symons, R. (1986) Self-cleavage of plus and minus RNA transcripts of avocada sunblotch viroid. Nucl. Acids Res. 14, 3627-40.
-
(1986)
Nucl. Acids Res.
, vol.14
, pp. 3627-3640
-
-
Hutchins, C.1
Rathjen, P.2
Forster, A.3
Symons, R.4
-
36
-
-
0028979545
-
Inhibition of pancreatic β-cell glucokinase by antisense RNA expression in transgenic mice: Mouse strain-dependent alteration in glucose tolerance
-
Ishihara, H., Tashiro, F., Ikuta, K., Asano, T., Katagiri, H., Inukai, K., Kikuchi, M., Yazaki, Y., Oka, Y. and Miyazaki, J. (1995) Inhibition of pancreatic β-cell glucokinase by antisense RNA expression in transgenic mice: mouse strain-dependent alteration in glucose tolerance. FEBS Letters 371, 329-32.
-
(1995)
FEBS Letters
, vol.371
, pp. 329-332
-
-
Ishihara, H.1
Tashiro, F.2
Ikuta, K.3
Asano, T.4
Katagiri, H.5
Inukai, K.6
Kikuchi, M.7
Yazaki, Y.8
Oka, Y.9
Miyazaki, J.10
-
37
-
-
0021229867
-
Inhibition of thymidine kinase gene expression by anti-sense RNA: A molecular approach to genetic analysis
-
Izant, J. and Weintraub, H. (1984) Inhibition of thymidine kinase gene expression by anti-sense RNA: A molecular approach to genetic analysis. Cell 36, 1007-15.
-
(1984)
Cell
, vol.36
, pp. 1007-1015
-
-
Izant, J.1
Weintraub, H.2
-
38
-
-
0026093944
-
Inhibition of human immunodeficiency virus type 1 multiplication by antisense and sense RNA expression
-
Joshi, S., van Brunschot, A., Asad, S., van der Elst, I., Read, S. and Bernstein, A. (1991) Inhibition of human immunodeficiency virus type 1 multiplication by antisense and sense RNA expression. J. Virol. 65, 5524-30.
-
(1991)
J. Virol.
, vol.65
, pp. 5524-5530
-
-
Joshi, S.1
Van Brunschot, A.2
Asad, S.3
Van Der Elst, I.4
Read, S.5
Bernstein, A.6
-
39
-
-
0023724675
-
Determinants that contribute to cytoplasmic stability of human c-fos and beta globin mRNAs are located at several sites in each mRNA
-
Kabnick, K. and Housman, D. (1988) Determinants that contribute to cytoplasmic stability of human c-fos and beta globin mRNAs are located at several sites in each mRNA. Mol. Cell. Biol. 8, 3244-50.
-
(1988)
Mol. Cell. Biol.
, vol.8
, pp. 3244-3250
-
-
Kabnick, K.1
Housman, D.2
-
40
-
-
0023770931
-
Conversion of normal behavior to shiverer by myelin basic protein antisense cDNA in transgenic mice
-
Katsuki, M., Sato, M., Kimura., Yokoyama, M., Kobayashi, K. and Nomura, T. (1988) Conversion of normal behavior to shiverer by myelin basic protein antisense cDNA in transgenic mice. Science 241, 593-5.
-
(1988)
Science
, vol.241
, pp. 593-595
-
-
Katsuki, M.1
Sato, M.2
Kimura3
Yokoyama, M.4
Kobayashi, K.5
Nomura, T.6
-
41
-
-
0025992237
-
Site specific cleavage by metal ion cofactors and inhibitors of m1 RNA, the catalytic subunit of RNaseP from Escherichia coli
-
Kazakov, S. and Altman, S. (1991) Site specific cleavage by metal ion cofactors and inhibitors of m1 RNA, the catalytic subunit of RNaseP from Escherichia coli. Proc. Natl Acad. Sci. USA 88, 9139-97.
-
(1991)
Proc. Natl Acad. Sci. USA
, vol.88
, pp. 9139-9197
-
-
Kazakov, S.1
Altman, S.2
-
42
-
-
0001879591
-
The structure of viroids and virusoids
-
Semancik, J.S. ed. Boca Raton, FL, USA: CRC Press
-
Keese, P. and Symons, R. (1987) The structure of viroids and virusoids. In Semancik, J.S. ed. Viroids and Viroid-like Pathogens. pp. 1-47. Boca Raton, FL, USA: CRC Press.
-
(1987)
Viroids and Viroid-like Pathogens
, pp. 1-47
-
-
Keese, P.1
Symons, R.2
-
43
-
-
0028287235
-
Partial rescue of a lethal phenotype of fragile bones in transgenic mice with a chimeric antisense gene directed against a mutated collagen gene
-
Khillan, J., Li, S. and Prockop, D. (1994) Partial rescue of a lethal phenotype of fragile bones in transgenic mice with a chimeric antisense gene directed against a mutated collagen gene. Proc. Natl Acad. Sci. USA 91, 6298-302.
-
(1994)
Proc. Natl Acad. Sci. USA
, vol.91
, pp. 6298-6302
-
-
Khillan, J.1
Li, S.2
Prockop, D.3
-
44
-
-
0023462809
-
Three dimensional model of the active site of the self-splicing rRNA precursor of Tetrahymena
-
Kim, S. and Cech, T. (1987) Three dimensional model of the active site of the self-splicing rRNA precursor of Tetrahymena. Proc. Natl Acad. Sci. USA 84, 8788-92.
-
(1987)
Proc. Natl Acad. Sci. USA
, vol.84
, pp. 8788-8792
-
-
Kim, S.1
Cech, T.2
-
45
-
-
0022410913
-
Stable reduction of thymidine kinase activity in cells expressing high levels of anti-sense RNA
-
Kim, S. and Wold, B. (1985) Stable reduction of thymidine kinase activity in cells expressing high levels of anti-sense RNA. Cell 42, 129-38.
-
(1985)
Cell
, vol.42
, pp. 129-138
-
-
Kim, S.1
Wold, B.2
-
46
-
-
0024424453
-
An antisense mRNA directs the covalent modification of the transcripts encoding fibroblast growth factor in Xenopus oocytes
-
Kimelman, D. and Kirschner, M. (1989) An antisense mRNA directs the covalent modification of the transcripts encoding fibroblast growth factor in Xenopus oocytes. Cell 59, 687-96.
-
(1989)
Cell
, vol.59
, pp. 687-696
-
-
Kimelman, D.1
Kirschner, M.2
-
47
-
-
0023189474
-
Antisense RNA inactivation of myosin heavy chain gene expression in Dictyostelium discoideum
-
Knecht, D. and Loomis, W. (1987) Antisense RNA inactivation of myosin heavy chain gene expression in Dictyostelium discoideum. Science 236, 1081-6.
-
(1987)
Science
, vol.236
, pp. 1081-1086
-
-
Knecht, D.1
Loomis, W.2
-
48
-
-
0025288707
-
N-myc mRNA forms an RNA-RNA duplex with endogenous antisense transcripts
-
Krystal, G., Armstrong, B. and Battey, J. (1990) N-myc mRNA forms an RNA-RNA duplex with endogenous antisense transcripts. Mol. Cell. Biol. 10, 4180-91.
-
(1990)
Mol. Cell. Biol.
, vol.10
, pp. 4180-4191
-
-
Krystal, G.1
Armstrong, B.2
Battey, J.3
-
49
-
-
0028177915
-
Reduced β2-microglobulin mRNA levels in transgenic mice expressing a designed hammerhead ribozyme
-
Larsson, S., Hotchkiss, G., Andang, M., Nyholm, T., Inzunza, J., Jansson, I. and Ahrlund-Richter, L. (1994) Reduced β2-microglobulin mRNA levels in transgenic mice expressing a designed hammerhead ribozyme. Nucl. Acids Res. 22, 2242-8.
-
(1994)
Nucl. Acids Res.
, vol.22
, pp. 2242-2248
-
-
Larsson, S.1
Hotchkiss, G.2
Andang, M.3
Nyholm, T.4
Inzunza, J.5
Jansson, I.6
Ahrlund-Richter, L.7
-
50
-
-
0026445371
-
Cytoplasmic delivery of ribozymes leads to efficient reduction of α-lactalbumin mRNA levels in C1271 mouse cells
-
L'Huillier, P., Davis, S. and Bellamy, A. (1992) Cytoplasmic delivery of ribozymes leads to efficient reduction of α-lactalbumin mRNA levels in C1271 mouse cells. EMBO J. 11, 4411-8.
-
(1992)
EMBO J.
, vol.11
, pp. 4411-4418
-
-
L'Huillier, P.1
Davis, S.2
Bellamy, A.3
-
51
-
-
0026785305
-
Inhibition of replication of HIV-1 by retroviral vectors expressing tat-antisense and anti-tat ribozyme RNA
-
Lo, K., Biasolo, M., Dehni, G., Palu, G. and Haseltine, W. (1992) Inhibition of replication of HIV-1 by retroviral vectors expressing tat-antisense and anti-tat ribozyme RNA. Virol. 190, 176-83.
-
(1992)
Virol.
, vol.190
, pp. 176-183
-
-
Lo, K.1
Biasolo, M.2
Dehni, G.3
Palu, G.4
Haseltine, W.5
-
52
-
-
0025305877
-
The IS10 antisense RNA blocks ribosome binding at the transposase translation initiation site
-
Ma, C. and Simons, R. (1990) The IS10 antisense RNA blocks ribosome binding at the transposase translation initiation site. EMBO J. 9, 1267-4.
-
(1990)
EMBO J.
, vol.9
, pp. 1267-1274
-
-
Ma, C.1
Simons, R.2
-
53
-
-
0027325826
-
Growth retardation in rats whose growth hormone gene expression was suppressed by antisense RNA transgene
-
Matsumoto, K., Kakidani, H., Takahashi, A., Nakagata, N., Anzai, M., Matsuzaki, Y., Miyata, K. and Utsumi, K. (1993) Growth retardation in rats whose growth hormone gene expression was suppressed by antisense RNA transgene. Mol. Reprod. Devel. 36, 53-8.
-
(1993)
Mol. Reprod. Devel.
, vol.36
, pp. 53-58
-
-
Matsumoto, K.1
Kakidani, H.2
Takahashi, A.3
Nakagata, N.4
Anzai, M.5
Matsuzaki, Y.6
Miyata, K.7
Utsumi, K.8
-
54
-
-
0029068474
-
Evaluation of an antisense RNA transgene for inhibiting growth hormone gene expression in transgenic rats
-
Matsumoto, K., Kakidani, H., Anzai, M., Nakagata, N., Takahashi, A., Takahashi, Y. and Miyata, K. (1995) Evaluation of an antisense RNA transgene for inhibiting growth hormone gene expression in transgenic rats. Devel. Genet. 16, 273-7.
-
(1995)
Devel. Genet.
, vol.16
, pp. 273-277
-
-
Matsumoto, K.1
Kakidani, H.2
Anzai, M.3
Nakagata, N.4
Takahashi, A.5
Takahashi, Y.6
Miyata, K.7
-
55
-
-
0343531938
-
Injected antisense RNAs specifically block messenger RNA translation in vivo
-
Melton, D. (1985) Injected antisense RNAs specifically block messenger RNA translation in vivo. Proc. Natl Acad. Sci. USA 82, 144-8.
-
(1985)
Proc. Natl Acad. Sci. USA
, vol.82
, pp. 144-148
-
-
Melton, D.1
-
56
-
-
0026771009
-
Role of I-A molecules in early stages of B cell maturation
-
Miki, N., Hatano, M., Wakita, K., Imoto, S., Nishikawa, S., Nishikawa, S.I. and Tokuhisa, T. (1992) Role of I-A molecules in early stages of B cell maturation. J. Immunol. 149, 801-7.
-
(1992)
J. Immunol.
, vol.149
, pp. 801-807
-
-
Miki, N.1
Hatano, M.2
Wakita, K.3
Imoto, S.4
Nishikawa, S.5
Nishikawa, S.I.6
Tokuhisa, T.7
-
57
-
-
0029123504
-
Disruption of hypothalamic-putuitary-adrenocortical system in transgenic mice expressing type II glucocorticoid receptor antisense ribonucleic acid permanently impairs T cell function: Effects on T cell trafficking and T cell responsiveness during postnatal development
-
Morale, M.C., Batticane, N., Gallo, F., Barden, N. and Marchetti, B. (1995) Disruption of hypothalamic-putuitary-adrenocortical system in transgenic mice expressing type II glucocorticoid receptor antisense ribonucleic acid permanently impairs T cell function: Effects on T cell trafficking and T cell responsiveness during postnatal development. Endocrinol. 136, 3949-60.
-
(1995)
Endocrinol.
, vol.136
, pp. 3949-3960
-
-
Morale, M.C.1
Batticane, N.2
Gallo, F.3
Barden, N.4
Marchetti, B.5
-
58
-
-
0027249144
-
iα2-specific antisense RNA in vivo inhibits neonatal growth
-
iα2-specific antisense RNA in vivo inhibits neonatal growth. Science 260, 991-5.
-
(1993)
Science
, vol.260
, pp. 991-995
-
-
Moxham, C.1
Hod, Y.2
Malvon, C.3
-
60
-
-
0025104043
-
Antisense RNA production in transgenic mice
-
Munir, M., Rossiter, B. and Caskey, C. (1990) Antisense RNA production in transgenic mice. Somatic Cell Mol. Genet. 16, 383-94.
-
(1990)
Somatic Cell Mol. Genet.
, vol.16
, pp. 383-394
-
-
Munir, M.1
Rossiter, B.2
Caskey, C.3
-
61
-
-
0025721986
-
Inhibition of c-erbA mRNA splicing by a naturally occurring antisense RNA
-
Munroe, S. and Lazar, M. (1991) Inhibition of c-erbA mRNA splicing by a naturally occurring antisense RNA. J. Biol. Chem. 266, 22083-6.
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 22083-22086
-
-
Munroe, S.1
Lazar, M.2
-
62
-
-
0026782215
-
Antisense inhibition of gene expression: A tool for studying the role of NMYC in the growth and differentiation of neuroectoderm-derived cells
-
Neckers, L., Rosolen, A. and Whitesell, L. (1992) Antisense inhibition of gene expression: A tool for studying the role of NMYC in the growth and differentiation of neuroectoderm-derived cells. J. Immunotherapy 12, 162-6.
-
(1992)
J. Immunotherapy
, vol.12
, pp. 162-166
-
-
Neckers, L.1
Rosolen, A.2
Whitesell, L.3
-
63
-
-
0027152144
-
Inhibition of tobacco NaDH-hydroxypyruvate reductase by expression of a heterologous antisense RNA derived from a cucumber cDNA: Implications for the mechanism of action of antisense RNAs
-
Oliver, M., Ferguson, D., Burke, J. and Velten, J. (1993) Inhibition of tobacco NaDH-hydroxypyruvate reductase by expression of a heterologous antisense RNA derived from a cucumber cDNA: Implications for the mechanism of action of antisense RNAs. Mol. Gen. Genet. 239, 425-34.
-
(1993)
Mol. Gen. Genet.
, vol.239
, pp. 425-434
-
-
Oliver, M.1
Ferguson, D.2
Burke, J.3
Velten, J.4
-
64
-
-
0029045372
-
Transient inhibition of angiotensinogen production in transgenic mice bearing an antisense angiotensinogen gene
-
Pedrazzini, T., Cousin, P., Aubert, J.F. and Brunner, H.R. (1995) Transient inhibition of angiotensinogen production in transgenic mice bearing an antisense angiotensinogen gene. Kidney International 47, 1638-46.
-
(1995)
Kidney International
, vol.47
, pp. 1638-1646
-
-
Pedrazzini, T.1
Cousin, P.2
Aubert, J.F.3
Brunner, H.R.4
-
65
-
-
0026543152
-
Impaired type II glucocortocoid receptor function in mice bearing antisense RNA transgene
-
Pepin, M., Pothier, F. and Barden, N. (1992) Impaired type II glucocortocoid receptor function in mice bearing antisense RNA transgene. Nature 355, 725-8.
-
(1992)
Nature
, vol.355
, pp. 725-728
-
-
Pepin, M.1
Pothier, F.2
Barden, N.3
-
66
-
-
0027183545
-
Ribozymes: A distinct class of metalloenzymes
-
Pyle, A. (1993) Ribozymes: a distinct class of metalloenzymes. Science 261, 709-14.
-
(1993)
Science
, vol.261
, pp. 709-714
-
-
Pyle, A.1
-
67
-
-
0027070730
-
In vivo treatment of human leukemia in a SCID mouse model with c-myb antisense oligodeoxynucleotides
-
Ratajczak, M., Kant, J., Luger, S., Hijiya, N., Zhang, J., Zon, G. and Gewirtz, A. (1992) In vivo treatment of human leukemia in a SCID mouse model with c-myb antisense oligodeoxynucleotides. Proc. Natl Acad. Sci. USA 89, 11823-7.
-
(1992)
Proc. Natl Acad. Sci. USA
, vol.89
, pp. 11823-11827
-
-
Ratajczak, M.1
Kant, J.2
Luger, S.3
Hijiya, N.4
Zhang, J.5
Zon, G.6
Gewirtz, A.7
-
68
-
-
0024435363
-
Studies on the hammerhead RNA self-cleaving domain
-
Ruffner, D., Dahm, S. and Uhlenbeck, O. (1989) Studies on the hammerhead RNA self-cleaving domain. Gene 82, 31-42.
-
(1989)
Gene
, vol.82
, pp. 31-42
-
-
Ruffner, D.1
Dahm, S.2
Uhlenbeck, O.3
-
70
-
-
0025363891
-
Ribozymes as potential anti-HIV-1 therapeutic agents
-
Sarver, N., Cantin, E., Chang, P., Zaia, J., Ladne, P., Stephens, D. and Rossi, J. (1990) Ribozymes as potential anti-HIV-1 therapeutic agents. Science 247, 1222-5.
-
(1990)
Science
, vol.247
, pp. 1222-1225
-
-
Sarver, N.1
Cantin, E.2
Chang, P.3
Zaia, J.4
Ladne, P.5
Stephens, D.6
Rossi, J.7
-
71
-
-
0027650964
-
Transgenic mice with antisense RNA against the nucleocapsid protein mRNA of mouse hepatitis virus
-
Sasaki, N., Hayashi, M., Aoyama, S., Yamashita, T., Miyoshi, I., Kasai, N. and Namioka, S. (1993) Transgenic mice with antisense RNA against the nucleocapsid protein mRNA of mouse hepatitis virus. J. Vet. Med. Sci. 55, 549-54.
-
(1993)
J. Vet. Med. Sci.
, vol.55
, pp. 549-554
-
-
Sasaki, N.1
Hayashi, M.2
Aoyama, S.3
Yamashita, T.4
Miyoshi, I.5
Kasai, N.6
Namioka, S.7
-
72
-
-
0025051353
-
Ribozymes correctly cleave a model substrate and endogenous RNA in vivo
-
Saxena, S. and Ackerman, E. (1990) Ribozymes correctly cleave a model substrate and endogenous RNA in vivo. J. Biol. Chem. 265, 17106-9.
-
(1990)
J. Biol. Chem.
, vol.265
, pp. 17106-17109
-
-
Saxena, S.1
Ackerman, E.2
-
73
-
-
0025872121
-
Ribozyme-mediated cleavage of c-fos mRNA reduces gene expression of DNA synthesis enzymes and metallothionine
-
Scanlon, K., Jiao, L., Funato, T., Wang, W., Tone, T., Rossi, J.J. and Kashani-Sabet, M. (1991) Ribozyme-mediated cleavage of c-fos mRNA reduces gene expression of DNA synthesis enzymes and metallothionine. Proc. Natl Acad. Sci. USA 88, 10591-5.
-
(1991)
Proc. Natl Acad. Sci. USA
, vol.88
, pp. 10591-10595
-
-
Scanlon, K.1
Jiao, L.2
Funato, T.3
Wang, W.4
Tone, T.5
Rossi, J.J.6
Kashani-Sabet, M.7
-
74
-
-
0024253944
-
Biological regulation by antisense RNA in prokaryotes
-
Simons, R. and Kleckner, N. (1988) Biological regulation by antisense RNA in prokaryotes. Ann. Rev. Genet. 22, 567-600.
-
(1988)
Ann. Rev. Genet.
, vol.22
, pp. 567-600
-
-
Simons, R.1
Kleckner, N.2
-
75
-
-
0025864336
-
Prevention of human immunodeficiency virus type 1 integrase expression in Escherichia coli by a ribozyme
-
Sioud, M. and Drlica, K. (1991) Prevention of human immunodeficiency virus type 1 integrase expression in Escherichia coli by a ribozyme. Proc. Natl Acad. Sci. USA 88, 7303-7.
-
(1991)
Proc. Natl Acad. Sci. USA
, vol.88
, pp. 7303-7307
-
-
Sioud, M.1
Drlica, K.2
-
76
-
-
0000878486
-
Antisense RNA inhibition of polygalacturaonase gene expression in transgenic tomatoes
-
Smith, C., Watson, C., Rau, J., Bird, C., Morris, P., Schuch, W. and Grierson, D. (1988) Antisense RNA inhibition of polygalacturaonase gene expression in transgenic tomatoes. Nature 334, 724-6.
-
(1988)
Nature
, vol.334
, pp. 724-726
-
-
Smith, C.1
Watson, C.2
Rau, J.3
Bird, C.4
Morris, P.5
Schuch, W.6
Grierson, D.7
-
77
-
-
0028327292
-
Dexamethasone non-suppression in transgenic mice expressing antisense RNA to the glucocorticoid receptor
-
Stec, I., Barden, N., Reul, J.M.H. and Holsboer, F. (1994) Dexamethasone non-suppression in transgenic mice expressing antisense RNA to the glucocorticoid receptor. J. Psychiatr. Res. 28, 1-5.
-
(1994)
J. Psychiatr. Res.
, vol.28
, pp. 1-5
-
-
Stec, I.1
Barden, N.2
Reul, J.M.H.3
Holsboer, F.4
-
78
-
-
0026562551
-
Expression of a chimeric ribozyme gene results in endonucleolytic cleavage of target mRNA and a concomitant reduction of gene expression in vivo
-
Steinecke, P., Herget, T. and Schreier, P. (1992) Expression of a chimeric ribozyme gene results in endonucleolytic cleavage of target mRNA and a concomitant reduction of gene expression in vivo. EMBO J. 11, 1525-30.
-
(1992)
EMBO J.
, vol.11
, pp. 1525-1530
-
-
Steinecke, P.1
Herget, T.2
Schreier, P.3
-
79
-
-
0025201180
-
Expression of chimeric tRNA-driven antisense transcripts renders NIH 3T3 cells highly resistant to Moloney murine leukemia virus replication
-
Sullenger, G.B., Lee, T., Smith, C., Ungers, G. and Gilboa, E. (1990) Expression of chimeric tRNA-driven antisense transcripts renders NIH 3T3 cells highly resistant to Moloney murine leukemia virus replication. Mol. Cell. Biol. 10, 6512-23.
-
(1990)
Mol. Cell. Biol.
, vol.10
, pp. 6512-6523
-
-
Sullenger, G.B.1
Lee, T.2
Smith, C.3
Ungers, G.4
Gilboa, E.5
-
80
-
-
0026879273
-
Making sense from antisense: A review of experimental data and developing ideas on sense-antisense peptide recognition
-
Tropsha, A., Kizer, J. and Chaiken, F. (1992) Making sense from antisense: a review of experimental data and developing ideas on sense-antisense peptide recognition. J. Mol. Recognition 5, 43-54.
-
(1992)
J. Mol. Recognition
, vol.5
, pp. 43-54
-
-
Tropsha, A.1
Kizer, J.2
Chaiken, F.3
-
81
-
-
0027370258
-
Protein enhancement of hammerhead ribozyme catalysis
-
Tsuchihashi, Z., Khosia, M. and Herschlag, D. (1993) Protein enhancement of hammerhead ribozyme catalysis. Science 262, 99-102.
-
(1993)
Science
, vol.262
, pp. 99-102
-
-
Tsuchihashi, Z.1
Khosia, M.2
Herschlag, D.3
-
82
-
-
0023221419
-
A small catalytic oligoribonucleotide
-
Uhlenbeck, O. (1987) A small catalytic oligoribonucleotide. Nature 328, 596-600.
-
(1987)
Nature
, vol.328
, pp. 596-600
-
-
Uhlenbeck, O.1
-
83
-
-
0028073946
-
Expression of GLUT-2 antisense RNA in beta-cells of transgenic mice leads to diabetes
-
Valera, A., Solanes, G., Fernandez-Alvarez, J., Pujol, A., Ferrer, J., Asins, G., Gomis, R. and Bosch, F. (1994) Expression of GLUT-2 antisense RNA in beta-cells of transgenic mice leads to diabetes. J. Biol. Chem. 269, 28543-416.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 28543-29416
-
-
Valera, A.1
Solanes, G.2
Fernandez-Alvarez, J.3
Pujol, A.4
Ferrer, J.5
Asins, G.6
Gomis, R.7
Bosch, F.8
-
84
-
-
0024238223
-
Modulation of eukaryotic gene expression by complementary RNA or DNA sequences
-
van der Krol, A., Mol, J. and Stuitje, A. (1988a) Modulation of eukaryotic gene expression by complementary RNA or DNA sequences. Biotechniques 6, 958-76.
-
(1988)
Biotechniques
, vol.6
, pp. 958-976
-
-
Van Der Krol, A.1
Mol, J.2
Stuitje, A.3
-
85
-
-
0000137303
-
An anti-sense chalcone synthase gene in transgenic plants inhibits flower pigmentation
-
van der Krol, A., Lenting, P., Veenstra, J., vander Meer, I., Koes, R., Gerats, A., Mol, J. and Stuitje, A. (1988b) An anti-sense chalcone synthase gene in transgenic plants inhibits flower pigmentation. Nature 333, 866-9.
-
(1988)
Nature
, vol.333
, pp. 866-869
-
-
Van Der Krol, A.1
Lenting, P.2
Veenstra, J.3
Vander Meer, I.4
Koes, R.5
Gerats, A.6
Mol, J.7
Stuitje, A.8
-
86
-
-
0027310938
-
In vivo infection of sheep by bovine leukemia virus mutants
-
Willems, L., Kettmann, R., Dequiedst, F., Portetelle, D., Voneche, V., Cornil, I., Kerkhofs, P., Burny, A. and Mammerick, M. (1993) In vivo infection of sheep by bovine leukemia virus mutants. J. Virol. 67, 4078-85.
-
(1993)
J. Virol.
, vol.67
, pp. 4078-4085
-
-
Willems, L.1
Kettmann, R.2
Dequiedst, F.3
Portetelle, D.4
Voneche, V.5
Cornil, I.6
Kerkhofs, P.7
Burny, A.8
Mammerick, M.9
-
87
-
-
0026026139
-
The protein coding region of c-myc mRNA contains a sequence that specifies rapid turnover and induction by protein synthesis inhibitors
-
Wisdom, R. and Lee, W. (1991) The protein coding region of c-myc mRNA contains a sequence that specifies rapid turnover and induction by protein synthesis inhibitors. Genes Devel. 5, 232-43.
-
(1991)
Genes Devel.
, vol.5
, pp. 232-243
-
-
Wisdom, R.1
Lee, W.2
-
88
-
-
0024117032
-
Ribosome pausing and stacking during translation of an eukaryotic mRNA
-
Wolin, S. and Walter, P. (1988) Ribosome pausing and stacking during translation of an eukaryotic mRNA. EMBO J. 7, 3559-69.
-
(1988)
EMBO J.
, vol.7
, pp. 3559-3569
-
-
Wolin, S.1
Walter, P.2
-
89
-
-
0027418252
-
Higher level organization of individual gene transcription and RNA splicing
-
Xing, Y., Johnson, C., Dobner, P. and Lawrence, J. (1993) Higher level organization of individual gene transcription and RNA splicing. Science 259, 1326-30.
-
(1993)
Science
, vol.259
, pp. 1326-1330
-
-
Xing, Y.1
Johnson, C.2
Dobner, P.3
Lawrence, J.4
|