-
1
-
-
0028884033
-
PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo
-
Alessi D. R., Cuenda A., Cohen P., Dudley D. T., Saltiel A. R. PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo. J. Biol. Chem. 270:1995;27489-27494.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 27489-27494
-
-
Alessi, D.R.1
Cuenda, A.2
Cohen, P.3
Dudley, D.T.4
Saltiel, A.R.5
-
2
-
-
0030344754
-
Neurotrophic factors in the treatment of peripheral neuropathy
-
Apfel S. C., Kessler J. A. Neurotrophic factors in the treatment of peripheral neuropathy. Ciba Found. Symp. 196:1996;98-108.
-
(1996)
Ciba Found. Symp.
, vol.196
, pp. 98-108
-
-
Apfel, S.C.1
Kessler, J.A.2
-
3
-
-
0028090302
-
The trk family of neurotrophin receptors
-
Barbacid M. The trk family of neurotrophin receptors. J. Neurobiol. 25:1994;1386-1403.
-
(1994)
J. Neurobiol.
, vol.25
, pp. 1386-1403
-
-
Barbacid, M.1
-
4
-
-
0024677597
-
Trophic factors and neuronal survival
-
Barde Y.-A. Trophic factors and neuronal survival. Neuron. 2:1989;1525-1534.
-
(1989)
Neuron
, vol.2
, pp. 1525-1534
-
-
Barde, Y.-A.1
-
5
-
-
0020338405
-
Purification of a new neurotrophic factor from mammalian brain
-
Barde Y.-A., Edgar D., Thoenen H. Purification of a new neurotrophic factor from mammalian brain. EMBO J. 1:1982;549-553.
-
(1982)
EMBO J.
, vol.1
, pp. 549-553
-
-
Barde, Y.-A.1
Edgar, D.2
Thoenen, H.3
-
6
-
-
0027966170
-
Disruption of NGF binding to the low affinity neurotrophin receptor p75LNTR reduces NGF binding to TrkA on PC12 cells
-
Barker P., Shooter E. Disruption of NGF binding to the low affinity neurotrophin receptor p75LNTR reduces NGF binding to TrkA on PC12 cells. Neuron. 13:1994;203-215.
-
(1994)
Neuron
, vol.13
, pp. 203-215
-
-
Barker, P.1
Shooter, E.2
-
7
-
-
0022137480
-
Microinjection of the ras oncogene protein into PC12 induces morphologic differentiation
-
Bar-Sagi D., Feramisco J. R. Microinjection of the ras oncogene protein into PC12 induces morphologic differentiation. Cell. 42:1985;841-848.
-
(1985)
Cell
, vol.42
, pp. 841-848
-
-
Bar-Sagi, D.1
Feramisco, J.R.2
-
8
-
-
0030932239
-
Intravenous basic fibroblast growth factor decreases brain injury resulting from focal ischemia in cats
-
Bethel A., Kirsch J. R., Koehler R. C., Finklestein S. P., Traystman R. J. Intravenous basic fibroblast growth factor decreases brain injury resulting from focal ischemia in cats. Stroke. 28:1997;609-615.
-
(1997)
Stroke
, vol.28
, pp. 609-615
-
-
Bethel, A.1
Kirsch, J.R.2
Koehler, R.C.3
Finklestein, S.P.4
Traystman, R.J.5
-
9
-
-
0030795798
-
Intrastriatal injection of an adenoviral vector expressing glial cell line-derived neurotrophic factor prevents dopaminergic neuron degeneration and behavioral impairment in a rat model of Parkinson disease
-
Bilang-Bleuel A., Revah F., Colin P., Locquet I., Robert J. J., Mallet J., Horellou P. Intrastriatal injection of an adenoviral vector expressing glial cell line-derived neurotrophic factor prevents dopaminergic neuron degeneration and behavioral impairment in a rat model of Parkinson disease. Proc. Natl. Acad. Sci. USA. 94:1997;8818-8823.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 8818-8823
-
-
Bilang-Bleuel, A.1
Revah, F.2
Colin, P.3
Locquet, I.4
Robert, J.J.5
Mallet, J.6
Horellou, P.7
-
10
-
-
0344086721
-
In vitro evaluation of GPI-1046, an immunophilin ligand with reported neurotrophic activity
-
Bilsland J., Young L., Williams B., Swain C., Hefti F., Harper S. In vitro evaluation of GPI-1046, an immunophilin ligand with reported neurotrophic activity. Eur. J. Neurosci. 10:1998;390.
-
(1998)
Eur. J. Neurosci.
, vol.10
, pp. 390
-
-
Bilsland, J.1
Young, L.2
Williams, B.3
Swain, C.4
Hefti, F.5
Harper, S.6
-
11
-
-
0027771191
-
Characterization of a pathway for ciliary neurotrophic factor signaling to the nucleus
-
Bonni A., Frank D. A., Schindler C., Greenberg M. E. Characterization of a pathway for ciliary neurotrophic factor signaling to the nucleus. Science. 262:1993;1575-1579.
-
(1993)
Science
, vol.262
, pp. 1575-1579
-
-
Bonni, A.1
Frank, D.A.2
Schindler, C.3
Greenberg, M.E.4
-
12
-
-
0032507611
-
CEP-1347/KT7515, a JNK pathway inhibitor, supports the in vitro survival of chick embryonic neurons
-
Borasio G. D., Horstmann S., Anneser J. M., Neff N. T., Glicksman M. A. CEP-1347/KT7515, a JNK pathway inhibitor, supports the in vitro survival of chick embryonic neurons. NeuroReport. 9:1998;1435-1439.
-
(1998)
NeuroReport
, vol.9
, pp. 1435-1439
-
-
Borasio, G.D.1
Horstmann, S.2
Anneser, J.M.3
Neff, N.T.4
Glicksman, M.A.5
-
13
-
-
0027256842
-
Involvement of ras p21 in neurotrophin-induced response of sensory, but not sympathetic neurons
-
Borasio G. D., Markus A., Wittinghofer A., Barde Y.-A., Heumann R. Involvement of ras p21 in neurotrophin-induced response of sensory, but not sympathetic neurons. J. Cell Biol. 121:1993;665-672.
-
(1993)
J. Cell Biol.
, vol.121
, pp. 665-672
-
-
Borasio, G.D.1
Markus, A.2
Wittinghofer, A.3
Barde, Y.-A.4
Heumann, R.5
-
14
-
-
0028916394
-
Functional interactions of neurotrophins and neurotrophin receptors
-
Bothwell M. Functional interactions of neurotrophins and neurotrophin receptors. Annu. Rev. Neurosci. 18:1995;223-253.
-
(1995)
Annu. Rev. Neurosci.
, vol.18
, pp. 223-253
-
-
Bothwell, M.1
-
15
-
-
0029609618
-
Telling axons where to grow: A role for Eph receptor tyrosine kinases in guidance
-
Brambilla R., Klein R. Telling axons where to grow: A role for Eph receptor tyrosine kinases in guidance. Mol. Cell. Neurosci. 6:1995;487-495.
-
(1995)
Mol. Cell. Neurosci.
, vol.6
, pp. 487-495
-
-
Brambilla, R.1
Klein, R.2
-
16
-
-
0028852791
-
Three-dimensional structure and actions of immunosuppressants and their immunophilins
-
Braun W., Kallen J., Mikol V., Walkinshaw M. D., Wuthrich K. Three-dimensional structure and actions of immunosuppressants and their immunophilins. FASEB J. 9:1995;63-72.
-
(1995)
FASEB J.
, vol.9
, pp. 63-72
-
-
Braun, W.1
Kallen, J.2
Mikol, V.3
Walkinshaw, M.D.4
Wuthrich, K.5
-
17
-
-
0032103082
-
Signaling by Eph receptors and their Ephrin ligands
-
Bruckner K., Klein R. Signaling by Eph receptors and their Ephrin ligands. Curr. Opin. Neurobiol. 8:1998;375-382.
-
(1998)
Curr. Opin. Neurobiol.
, vol.8
, pp. 375-382
-
-
Bruckner, K.1
Klein, R.2
-
18
-
-
0029160069
-
Protein kinase B (Akt) in phosphatidylinositol-3-OH kinase signal transduction
-
Burgering B., Coffer P. Protein kinase B (Akt) in phosphatidylinositol-3-OH kinase signal transduction. Nature. 376:1995;599-602.
-
(1995)
Nature
, vol.376
, pp. 599-602
-
-
Burgering, B.1
Coffer, P.2
-
19
-
-
0030608467
-
Medial septal cholinergic neurons express c-Jun but do not undergo DNA fragmentation after fornix-fimbria transections
-
Butterworth N. J., Dragunow M. Medial septal cholinergic neurons express c-Jun but do not undergo DNA fragmentation after fornix-fimbria transections. Mol. Brain Res. 43:1996;1-12.
-
(1996)
Mol. Brain Res.
, vol.43
, pp. 1-12
-
-
Butterworth, N.J.1
Dragunow, M.2
-
20
-
-
0029805770
-
Death of oligodendrocytes mediated by the interaction of nerve growth factor with its receptor p75
-
Casaccia-Bonnefil P., Carter B. D., Dobrowsky R. T., Chao M. V. Death of oligodendrocytes mediated by the interaction of nerve growth factor with its receptor p75. Nature. 383:1996;716-719.
-
(1996)
Nature
, vol.383
, pp. 716-719
-
-
Casaccia-Bonnefil, P.1
Carter, B.D.2
Dobrowsky, R.T.3
Chao, M.V.4
-
21
-
-
0026730310
-
Neurotrophin receptors: A window into neuronal differentiation
-
Chao M. V. Neurotrophin receptors: A window into neuronal differentiation. Neuron. 9:1992;583-593.
-
(1992)
Neuron
, vol.9
, pp. 583-593
-
-
Chao, M.V.1
-
23
-
-
0030781187
-
Ligand-induced changes in integrin expression regulate neuronal adhesion and neurite outgrowth
-
Condic M. L., Letourneau P. C. Ligand-induced changes in integrin expression regulate neuronal adhesion and neurite outgrowth. Nature. 389:1997;852-856.
-
(1997)
Nature
, vol.389
, pp. 852-856
-
-
Condic, M.L.1
Letourneau, P.C.2
-
24
-
-
0028228616
-
Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells
-
Cowley S., Paterson H., Kemp P., Marshall C. Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells. Cell. 77:1994;841-852.
-
(1994)
Cell
, vol.77
, pp. 841-852
-
-
Cowley, S.1
Paterson, H.2
Kemp, P.3
Marshall, C.4
-
25
-
-
0029834669
-
Mitogen-activated protein kinase-independent pathways mediate the effects of nerve growth factor and cAMP on neuronal survival
-
Creedon D. J., Johnson E. M. Jr., Lawrence J. C. Jr. Mitogen-activated protein kinase-independent pathways mediate the effects of nerve growth factor and cAMP on neuronal survival. J. Biol. Chem. 271:1996;20713-20718.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 20713-20718
-
-
Creedon, D.J.1
Johnson E.M., Jr.2
Lawrence J.C., Jr.3
-
26
-
-
0026539931
-
The primary structure of MEK, a protein kinase that phosphorylates the ERK gene product
-
Crews C., Alessandrini A., Erikson E. The primary structure of MEK, a protein kinase that phosphorylates the ERK gene product. Science. 258:1992;478-480.
-
(1992)
Science
, vol.258
, pp. 478-480
-
-
Crews, C.1
Alessandrini, A.2
Erikson, E.3
-
27
-
-
0027330994
-
P75-deficient trigeminal sensory neurons have an altered response to NGF but not to other neurotrophins
-
Davies A. M., Lee K. F., Jaenisch R. p75-deficient trigeminal sensory neurons have an altered response to NGF but not to other neurotrophins. Neuron. 11:1993;565-575.
-
(1993)
Neuron
, vol.11
, pp. 565-575
-
-
Davies, A.M.1
Lee, K.F.2
Jaenisch, R.3
-
28
-
-
0029761702
-
Signal-transducing protein phosphorylation cascades mediated by Ras/Rho proteins in the mammalian cell: The potential for multiplex signalling
-
Denhardt D. T. Signal-transducing protein phosphorylation cascades mediated by Ras/Rho proteins in the mammalian cell: The potential for multiplex signalling. Biochem. J. 318:1996;729-747.
-
(1996)
Biochem. J.
, vol.318
, pp. 729-747
-
-
Denhardt, D.T.1
-
29
-
-
0031054670
-
Insulin-like growth factor and potassium depolarization maintain neuronal survival by distinct pathways: Possible involvement of PI 3-kinase in IGF-1 signaling
-
D'Mello S. R., Borodezt K., Soltoff S. P. Insulin-like growth factor and potassium depolarization maintain neuronal survival by distinct pathways: Possible involvement of PI 3-kinase in IGF-1 signaling. J. Neurosci. 17:1997;1548-1560.
-
(1997)
J. Neurosci.
, vol.17
, pp. 1548-1560
-
-
D'Mello, S.R.1
Borodezt, K.2
Soltoff, S.P.3
-
30
-
-
0028108788
-
Activation of the sphingomyelin cycle through the low affinity neurotrophin receptor
-
Dobrowsky R., Werner M., Castellino A., Chao M., Hannun Y. Activation of the sphingomyelin cycle through the low affinity neurotrophin receptor. Science. 265:1994;1596-1599.
-
(1994)
Science
, vol.265
, pp. 1596-1599
-
-
Dobrowsky, R.1
Werner, M.2
Castellino, A.3
Chao, M.4
Hannun, Y.5
-
31
-
-
0023763087
-
Axon guidance and the patterning of neuronal projections in vertebrates
-
Dodd J., Jessell T. M. Axon guidance and the patterning of neuronal projections in vertebrates. Science. 242:1988;692-699.
-
(1988)
Science
, vol.242
, pp. 692-699
-
-
Dodd, J.1
Jessell, T.M.2
-
32
-
-
0343765729
-
Rediscovering an old friend, IGF-1: Potential use in the treatment of neurodegenerative diseases
-
Doré S., Kar S., Quirion R. Rediscovering an old friend, IGF-1: Potential use in the treatment of neurodegenerative diseases. Trends Neurosci. 20:1997;326-331.
-
(1997)
Trends Neurosci.
, vol.20
, pp. 326-331
-
-
Doré, S.1
Kar, S.2
Quirion, R.3
-
33
-
-
0031053586
-
Regulation of neuronal survival by the serine-threonine protein kinase Akt
-
Dudek H., Datta S. R., Franke T. F., Birnbaum M. J., Yao R., Cooper G. M., Segal R. A., Kaplan D. R., Greenberg M. E. Regulation of neuronal survival by the serine-threonine protein kinase Akt. Science. 275:1997;661-665.
-
(1997)
Science
, vol.275
, pp. 661-665
-
-
Dudek, H.1
Datta, S.R.2
Franke, T.F.3
Birnbaum, M.J.4
Yao, R.5
Cooper, G.M.6
Segal, R.A.7
Kaplan, D.R.8
Greenberg, M.E.9
-
34
-
-
0032518236
-
Bone morphogenetic proteins and their receptors: Potential functions in the brain
-
Ebendal T., Bengtsson H., Soderstrom S. Bone morphogenetic proteins and their receptors: Potential functions in the brain. J. Neurosci. Res. 51:1998;139-146.
-
(1998)
J. Neurosci. Res.
, vol.51
, pp. 139-146
-
-
Ebendal, T.1
Bengtsson, H.2
Soderstrom, S.3
-
35
-
-
0027601031
-
A golden age for cell adhesion
-
Edelman G. M. A golden age for cell adhesion. Cell Adh. Commun. 1:1993;1-7.
-
(1993)
Cell Adh. Commun.
, vol.1
, pp. 1-7
-
-
Edelman, G.M.1
-
36
-
-
0032032404
-
Role of the Jun kinase pathway in the regulation of c-Jun expression and apoptosis in sympathetic neurons
-
Eilers A., Whitfield J., Babij C., Rubin L., Ham J. Role of the Jun kinase pathway in the regulation of c-Jun expression and apoptosis in sympathetic neurons. J. Neurosci. 18:1998;1713-1724.
-
(1998)
J. Neurosci.
, vol.18
, pp. 1713-1724
-
-
Eilers, A.1
Whitfield, J.2
Babij, C.3
Rubin, L.4
Ham, J.5
-
37
-
-
0005868926
-
Intracerebroventricular infusion of nerve growth factor in three patients with Alzheimer's disease
-
Eriksdotter J. M., Nordberg A., Amberla K., Backman L., Ebendal T., Meyerson B., Olson L., Seiger A., Shigeta M., Theodorsson E., Viitanen M., Winblad B., Wahlund L. O. Intracerebroventricular infusion of nerve growth factor in three patients with Alzheimer's disease. Dement. Geriatr. Cogn. Disord. 9:1998;246-257.
-
(1998)
Dement. Geriatr. Cogn. Disord.
, vol.9
, pp. 246-257
-
-
Eriksdotter, J.M.1
Nordberg, A.2
Amberla, K.3
Backman, L.4
Ebendal, T.5
Meyerson, B.6
Olson, L.7
Seiger, A.8
Shigeta, M.9
Theodorsson, E.10
Viitanen, M.11
Winblad, B.12
Wahlund, L.O.13
-
38
-
-
0027946686
-
Altered gene expression in neurons during programmed cell death: Identification ofc-jun
-
Estus S., Zaks W. J., Freeman R. S., Gruda M., Bravo R., Johnson E. M. Jr. Altered gene expression in neurons during programmed cell death: Identification ofc-jun. J. Cell Biol. 127:1994;1717-1727.
-
(1994)
J. Cell Biol.
, vol.127
, pp. 1717-1727
-
-
Estus, S.1
Zaks, W.J.2
Freeman, R.S.3
Gruda, M.4
Bravo, R.5
Johnson E.M., Jr.6
-
39
-
-
0031044561
-
MEKKs, GCKs, MLKs, PAKs, TAKs, and TPLs: Upstream regulators of the c-Jun amino-terminal kinases
-
Fanger G. R., Gerwins P., Widmann C., Jarpe M. B., Johnson G. L. MEKKs, GCKs, MLKs, PAKs, TAKs, and TPLs: Upstream regulators of the c-Jun amino-terminal kinases. Curr. Opin. Genet. Dev. 7:1997;67-74.
-
(1997)
Curr. Opin. Genet. Dev.
, vol.7
, pp. 67-74
-
-
Fanger, G.R.1
Gerwins, P.2
Widmann, C.3
Jarpe, M.B.4
Johnson, G.L.5
-
40
-
-
0027398553
-
Blood-brain barrier penetration and in vivo activity of an NGF conjugate
-
Friden P. M., Walus L. R., Watson P., Doctrow S. R., Kozarich J. W., Bäckman C., Bergman H., Hoffer B., Bloom F., Granholm A.-C. Blood-brain barrier penetration and in vivo activity of an NGF conjugate. Science. 259:1993;373-377.
-
(1993)
Science
, vol.259
, pp. 373-377
-
-
Friden, P.M.1
Walus, L.R.2
Watson, P.3
Doctrow, S.R.4
Kozarich, J.W.5
Bäckman, C.6
Bergman, H.7
Hoffer, B.8
Bloom, F.9
Granholm, A.-C.10
-
41
-
-
0028276809
-
Implanted fibroblasts genetically engineered to produce brain-derived neurotrophic factor prevent 1-methyl-4-phenylpyridinium toxicity to dopaminergic neurons in the rat
-
Frim D. M., Uhler T. A., Galpern W. R., Beal M. F., Breakefield X. O., Isacson O. Implanted fibroblasts genetically engineered to produce brain-derived neurotrophic factor prevent 1-methyl-4-phenylpyridinium toxicity to dopaminergic neurons in the rat. Proc. Natl. Acad. Sci. USA. 91:1994;5104-5108.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 5104-5108
-
-
Frim, D.M.1
Uhler, T.A.2
Galpern, W.R.3
Beal, M.F.4
Breakefield, X.O.5
Isacson, O.6
-
42
-
-
0028153969
-
Effect of AIT-082, a purine analog, on working memory in normal and aged mice
-
Glasky A. J., Melchior C. L., Pirzadeh B., Heydari N., Ritzmann R. F. Effect of AIT-082, a purine analog, on working memory in normal and aged mice. Pharmacol. Biochem. Behav. 47:1994;325-329.
-
(1994)
Pharmacol. Biochem. Behav.
, vol.47
, pp. 325-329
-
-
Glasky, A.J.1
Melchior, C.L.2
Pirzadeh, B.3
Heydari, N.4
Ritzmann, R.F.5
-
43
-
-
0030801584
-
AIT-082, a novel purine derivative with neuroregenerative properties
-
Glasky A. J., Glasky M. S., Ritzmann R. F., Rathbone M. P. AIT-082, a novel purine derivative with neuroregenerative properties. Exp. Opin. Invest. Drugs. 6:1997;1413-1417.
-
(1997)
Exp. Opin. Invest. Drugs
, vol.6
, pp. 1413-1417
-
-
Glasky, A.J.1
Glasky, M.S.2
Ritzmann, R.F.3
Rathbone, M.P.4
-
44
-
-
0031309575
-
FK506 and the role of the immunophilins in nerve regeneration
-
Gold B. G. FK506 and the role of the immunophilins in nerve regeneration. Mol. Neurobiol. 15:1997;285-306.
-
(1997)
Mol. Neurobiol.
, vol.15
, pp. 285-306
-
-
Gold, B.G.1
-
45
-
-
0027351577
-
Developmental mechanisms that generate precise patterns of neuronal connectivity
-
Goodman C. S., Shatz C. J. Developmental mechanisms that generate precise patterns of neuronal connectivity. Cell/Neuron. 72:1993;77-98.
-
(1993)
Cell/Neuron
, vol.72
, pp. 77-98
-
-
Goodman, C.S.1
Shatz, C.J.2
-
46
-
-
0028019114
-
Neurotrophin-6 is a new member of the nerve growth factor family
-
Götz R., Köster R., Winkler C., Raulf F., Lottspeich F., Schartl M., Thoenen H. Neurotrophin-6 is a new member of the nerve growth factor family. Nature. 372:1994;266-269.
-
(1994)
Nature
, vol.372
, pp. 266-269
-
-
Götz, R.1
Köster, R.2
Winkler, C.3
Raulf, F.4
Lottspeich, F.5
Schartl, M.6
Thoenen, H.7
-
47
-
-
16944366150
-
Cellular delivery of neurotrophin-3 promotes corticospinal axonal growth and partial functional recovery after spinal cord injury
-
Grill R., Murai K., Blesch A., Gage F. H., Tuszynski M. H. Cellular delivery of neurotrophin-3 promotes corticospinal axonal growth and partial functional recovery after spinal cord injury. J. Neurosci. 17:1997;5560-5572.
-
(1997)
J. Neurosci.
, vol.17
, pp. 5560-5572
-
-
Grill, R.1
Murai, K.2
Blesch, A.3
Gage, F.H.4
Tuszynski, M.H.5
-
48
-
-
0025907893
-
Evolutionary studies of the nerve growth factor family reveal a novel member abundantly expressed in Xenopus ovary
-
Hallböök F., Ibáñez C. F., Persson H. Evolutionary studies of the nerve growth factor family reveal a novel member abundantly expressed in Xenopus ovary. Neuron. 6:1991;845-858.
-
(1991)
Neuron
, vol.6
, pp. 845-858
-
-
Hallböök, F.1
Ibáñez, C.F.2
Persson, H.3
-
49
-
-
0030953519
-
Gene therapy of murine motor neuron disease using adenoviral vectors for neurotrophic factors
-
Haase G., Kennel P., Pettmann B., Vigne E., Akli S., Revah F., Schmalbruch H., Kahn A. Gene therapy of murine motor neuron disease using adenoviral vectors for neurotrophic factors. Nat. Med. 3:1997;429-436.
-
(1997)
Nat. Med.
, vol.3
, pp. 429-436
-
-
Haase, G.1
Kennel, P.2
Pettmann, B.3
Vigne, E.4
Akli, S.5
Revah, F.6
Schmalbruch, H.7
Kahn, A.8
-
50
-
-
0029012476
-
A c-Jun dominant negative mutant protects sympathetic neurons against programmed cell death
-
Ham J., Babij C., Whitfield J., Pfarr C. M., Lallemand D., Yaniv M., Rubin L. L. A c-Jun dominant negative mutant protects sympathetic neurons against programmed cell death. Neuron. 14:1995;927-939.
-
(1995)
Neuron
, vol.14
, pp. 927-939
-
-
Ham, J.1
Babij, C.2
Whitfield, J.3
Pfarr, C.M.4
Lallemand, D.5
Yaniv, M.6
Rubin, L.L.7
-
51
-
-
0019796498
-
Neuronal death in the spinal ganglia of the chick embyro and its reduction by nerve growth factor
-
Hamburger V., Brunso-Bechthold J. K., Yip J. W. Neuronal death in the spinal ganglia of the chick embyro and its reduction by nerve growth factor. J. Neurosci. 1:1981;60-71.
-
(1981)
J. Neurosci.
, vol.1
, pp. 60-71
-
-
Hamburger, V.1
Brunso-Bechthold, J.K.2
Yip, J.W.3
-
52
-
-
0344517861
-
Small molecule neurotrophic factor mimetics
-
Hefti F., Harper S., Bristow L., Boyce S., Swain C. Small molecule neurotrophic factor mimetics. Int. J. Neuropsychopharmacol. 1:1998;S10.
-
(1998)
Int. J. Neuropsychopharmacol.
, vol.1
, pp. 10
-
-
Hefti, F.1
Harper, S.2
Bristow, L.3
Boyce, S.4
Swain, C.5
-
53
-
-
0028897113
-
Transcriptional regulation by extracellular signals: Mechanisms and specificity
-
Hill C., Treisman R. Transcriptional regulation by extracellular signals: Mechanisms and specificity. Cell. 80:1995;199-211.
-
(1995)
Cell
, vol.80
, pp. 199-211
-
-
Hill, C.1
Treisman, R.2
-
54
-
-
0032524763
-
Inhibitors of p38 mitogen-activated protein kinase promote neuronal survival in vitro
-
Horstmann S., Kahle P. J., Borasio G. D. Inhibitors of p38 mitogen-activated protein kinase promote neuronal survival in vitro. J. Neurosci. Res. 52:1998;483-490.
-
(1998)
J. Neurosci. Res.
, vol.52
, pp. 483-490
-
-
Horstmann, S.1
Kahle, P.J.2
Borasio, G.D.3
-
55
-
-
0029064557
-
Neurotrophic factors: From structure-function studies to designing effective therapeutics
-
Ibáñez C. F. Neurotrophic factors: From structure-function studies to designing effective therapeutics. TIBTECH. 13:1995;217-227.
-
(1995)
TIBTECH
, vol.13
, pp. 217-227
-
-
Ibáñez, C.F.1
-
56
-
-
0029940555
-
The neurotrophins and CNTF: Two families of collaborative neurotrophic factors
-
Ip N. Y., Yancopoulos G. D. The neurotrophins and CNTF: Two families of collaborative neurotrophic factors. Annu. Rev. Neurosci. 19:1996;491-515.
-
(1996)
Annu. Rev. Neurosci.
, vol.19
, pp. 491-515
-
-
Ip, N.Y.1
Yancopoulos, G.D.2
-
57
-
-
0028031527
-
The mitogen-activated protein kinase cascade is activated by B-Raf in response to nerve growth factor through interaction with p21ras
-
Jaiswal R. K., Moodie S. A., Wolfman A., Landreth G. E. The mitogen-activated protein kinase cascade is activated by B-Raf in response to nerve growth factor through interaction with p21ras. Mol. Cell. Biol. 14:1994;6944-6953.
-
(1994)
Mol. Cell. Biol.
, vol.14
, pp. 6944-6953
-
-
Jaiswal, R.K.1
Moodie, S.A.2
Wolfman, A.3
Landreth, G.E.4
-
58
-
-
0027050178
-
Nerve growth factor mediates signal transduction through trk homodimer receptors
-
Jing S., Tapley P., Barbacid M. Nerve growth factor mediates signal transduction through trk homodimer receptors. Neuron. 9:1992;1067-1079.
-
(1992)
Neuron
, vol.9
, pp. 1067-1079
-
-
Jing, S.1
Tapley, P.2
Barbacid, M.3
-
59
-
-
0030997674
-
Schizophrenia and neurotrophin-3 alleles
-
Jonsson E., Brene S., Zhang X. R., Nimgaonkar V. L., Tylec A., Schalling M., Sedvall G. Schizophrenia and neurotrophin-3 alleles. Acta Psychiatr. Scand. 1997;414-419.
-
(1997)
Acta Psychiatr. Scand.
, pp. 414-419
-
-
Jonsson, E.1
Brene, S.2
Zhang, X.R.3
Nimgaonkar, V.L.4
Tylec, A.5
Schalling, M.6
Sedvall, G.7
-
60
-
-
15144358619
-
Neurotrophic 3,9-bis[(alkylthio)methyl]- And -bis(alkoxymethyl)-K-252a derivatives
-
Kaneko M., Saito Y., Saito H., Matsumoto T., Matsuda Y., Vaught J. L., Dionne C. A., Angeles T. S., Glicksman M. A., Neff N. T., Rotella D. P., Kauer J. C., Mallamo J. P., Hudkins R. L., Murakata C. Neurotrophic 3,9-bis[(alkylthio)methyl]- and -bis(alkoxymethyl)-K-252a derivatives. J. Med. Chem. 40:1997;1863-1869.
-
(1997)
J. Med. Chem.
, vol.40
, pp. 1863-1869
-
-
Kaneko, M.1
Saito, Y.2
Saito, H.3
Matsumoto, T.4
Matsuda, Y.5
Vaught, J.L.6
Dionne, C.A.7
Angeles, T.S.8
Glicksman, M.A.9
Neff, N.T.10
Rotella, D.P.11
Kauer, J.C.12
Mallamo, J.P.13
Hudkins, R.L.14
Murakata, C.15
-
61
-
-
0031028730
-
Suppression of c-Myc-induced apoptosis by Ras signalling through PI(3)K and PKB
-
Kauffmann-Zeh A., Rodriguez-Viciana P., Ulrich E., Gilbert C., Coffer P., Downward J., Evan G. Suppression of c-Myc-induced apoptosis by Ras signalling through PI(3)K and PKB. Nature. 385:1997;544-548.
-
(1997)
Nature
, vol.385
, pp. 544-548
-
-
Kauffmann-Zeh, A.1
Rodriguez-Viciana, P.2
Ulrich, E.3
Gilbert, C.4
Coffer, P.5
Downward, J.6
Evan, G.7
-
62
-
-
0030760175
-
Intracisternal basic fibroblast growth factor enhances functional recovery and up-regulates the expression of a molecular marker of neuronal sprouting following focal cerebral infarction
-
Kawamata T., Dietrich W. D., Schallert T., Gotts J. E., Cocke R. R., Benowitz L. I., Finklestein S. P. Intracisternal basic fibroblast growth factor enhances functional recovery and up-regulates the expression of a molecular marker of neuronal sprouting following focal cerebral infarction. Proc. Natl. Acad. Sci. USA. 94:1997;8179-8184.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 8179-8184
-
-
Kawamata, T.1
Dietrich, W.D.2
Schallert, T.3
Gotts, J.E.4
Cocke, R.R.5
Benowitz, L.I.6
Finklestein, S.P.7
-
63
-
-
0030808984
-
Apoptosis induced by withdrawal of trophic factors is mediated by p38 mitogen-activated protein kinase
-
Kummer J. L., Rao P. K., Heidenreich K. A. Apoptosis induced by withdrawal of trophic factors is mediated by p38 mitogen-activated protein kinase. J. Biol. Chem. 272:1997;20490-20494.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 20490-20494
-
-
Kummer, J.L.1
Rao, P.K.2
Heidenreich, K.A.3
-
64
-
-
0029744885
-
Sounding the alarm: Protein kinase cascades activated by stress and inflammation
-
Kyriakis J. M., Avruch J. Sounding the alarm: protein kinase cascades activated by stress and inflammation. J. Biol. Chem. 271:1996;24313-24316.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 24313-24316
-
-
Kyriakis, J.M.1
Avruch, J.2
-
65
-
-
0031861901
-
Cloning and expression of a novel neurotrophin, NT-7, from carp
-
Lai K.-O., Fu W.-Y., Ip F. C. F., Ip N. Y. Cloning and expression of a novel neurotrophin, NT-7, from carp. Mol. Cell. Neurosci. 11:1998;64-76.
-
(1998)
Mol. Cell. Neurosci.
, vol.11
, pp. 64-76
-
-
Lai, K.-O.1
Fu, W.-Y.2
Ip, F.C.F.3
Ip, N.Y.4
-
66
-
-
0028074621
-
Ras-dependent growth factor regulation of MEK kinase in PC12 cells
-
Lange-Carter C. A., Johnson G. L. Ras-dependent growth factor regulation of MEK kinase in PC12 cells. Science. 265:1994;1458-1461.
-
(1994)
Science
, vol.265
, pp. 1458-1461
-
-
Lange-Carter, C.A.1
Johnson, G.L.2
-
67
-
-
0026747063
-
Targeted mutation of the gene encoding the low affinity NGF receptor p75 leads to deficits in the peripheral sensory nervous system
-
Lee K.-F., Li E., Huber L. J., Landis S. C., Sharpe A. H., Chao M. V., Jaenisch R. Targeted mutation of the gene encoding the low affinity NGF receptor p75 leads to deficits in the peripheral sensory nervous system. Cell. 69:1992;737-749.
-
(1992)
Cell
, vol.69
, pp. 737-749
-
-
Lee, K.-F.1
Li, E.2
Huber, L.J.3
Landis, S.C.4
Sharpe, A.H.5
Chao, M.V.6
Jaenisch, R.7
-
68
-
-
0024451643
-
Molecular cloning and expression of brain-derived neurotrophic factor
-
Leibrock J., Lottspeich F., Hohn A., Hofer M., Hengerer B., Masiakowski P., Thoenen H., Barde Y.-A. Molecular cloning and expression of brain-derived neurotrophic factor. Nature. 341:1989;149-152.
-
(1989)
Nature
, vol.341
, pp. 149-152
-
-
Leibrock, J.1
Lottspeich, F.2
Hohn, A.3
Hofer, M.4
Hengerer, B.5
Masiakowski, P.6
Thoenen, H.7
Barde, Y.-A.8
-
69
-
-
0028912281
-
Small peptide mimics of nerve growth factor bind TrkA receptors and affect biological responses
-
LeSauteur L., Wei L., Gibbs B. F., Saragovi H. U. Small peptide mimics of nerve growth factor bind TrkA receptors and affect biological responses. J. Biol. Chem. 270:1995;6564-6569.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 6564-6569
-
-
Lesauteur, L.1
Wei, L.2
Gibbs, B.F.3
Saragovi, H.U.4
-
70
-
-
0023236055
-
The nerve growth factor 35 years later
-
Levi-Montalcini R. The nerve growth factor 35 years later. Science. 237:1987;1154-1162.
-
(1987)
Science
, vol.237
, pp. 1154-1162
-
-
Levi-Montalcini, R.1
-
71
-
-
0030273438
-
GDNF in a bind with known orphan: Accessory implicated in a new twist
-
Lindsay R. M., Yancopoulos G. D. GDNF in a bind with known orphan: Accessory implicated in a new twist. Neuron. 17:1996;571-574.
-
(1996)
Neuron
, vol.17
, pp. 571-574
-
-
Lindsay, R.M.1
Yancopoulos, G.D.2
-
72
-
-
0029879308
-
TrkA activation is sufficient to rescue axotomized cholinergic neurons
-
Lucidi-Phillipi C. A., Clary D. O., Reichardt L. F., Gage F. H. TrkA activation is sufficient to rescue axotomized cholinergic neurons. Neuron. 16:1996;653-663.
-
(1996)
Neuron
, vol.16
, pp. 653-663
-
-
Lucidi-Phillipi, C.A.1
Clary, D.O.2
Reichardt, L.F.3
Gage, F.H.4
-
73
-
-
17344374130
-
Motoneuron apoptosis is blocked by CEP-1347 (KT 7515), a novel inhibitor of the JNK signaling pathway
-
Maroney A. C., Glicksman M. C., Basma A. N., Walton K. M., Knight E. Jr., Murphy C. A., Bartlett B. A., Finn J. P., Angeles T., Matsuda Y., Neff N. T., Dionne C. A. Motoneuron apoptosis is blocked by CEP-1347 (KT 7515), a novel inhibitor of the JNK signaling pathway. J. Neurosci. 18:1998;104-111.
-
(1998)
J. Neurosci.
, vol.18
, pp. 104-111
-
-
Maroney, A.C.1
Glicksman, M.C.2
Basma, A.N.3
Walton, K.M.4
Knight E., Jr.5
Murphy, C.A.6
Bartlett, B.A.7
Finn, J.P.8
Angeles, T.9
Matsuda, Y.10
Neff, N.T.11
Dionne, C.A.12
-
74
-
-
0030884103
-
PKB/Akt: Connecting phosphoinositide 3-kinase to cell survival and beyond
-
Marte B. M., Downward J. PKB/Akt: connecting phosphoinositide 3-kinase to cell survival and beyond. Trends Biochem. Sci. 22:1997;355-358.
-
(1997)
Trends Biochem. Sci.
, vol.22
, pp. 355-358
-
-
Marte, B.M.1
Downward, J.2
-
75
-
-
0028305243
-
Encapsulated genetically engineered fibroblasts: Release of nerve growth factor and effects in vivo on recovery of cholinergic markers after devascularizing cortical lesions
-
Maysinger D., Piccardo P., Liberini P., Jalsenjak I., Cuello C. Encapsulated genetically engineered fibroblasts: Release of nerve growth factor and effects in vivo on recovery of cholinergic markers after devascularizing cortical lesions. Neurochem. Int. 24:1994;495-503.
-
(1994)
Neurochem. Int.
, vol.24
, pp. 495-503
-
-
Maysinger, D.1
Piccardo, P.2
Liberini, P.3
Jalsenjak, I.4
Cuello, C.5
-
76
-
-
0026766860
-
The nerve growth factor family of receptors
-
Meakin S. O., Shooter E. M. The nerve growth factor family of receptors. Trends Neurosci. 15:1992;323-331.
-
(1992)
Trends Neurosci.
, vol.15
, pp. 323-331
-
-
Meakin, S.O.1
Shooter, E.M.2
-
77
-
-
0030793114
-
Sonic hedgehog promotes the survival of specific CNS neuron populations and protects these cells from toxic insultin vitro
-
Miao N., Wang M., Ott J. A., D'Alessandro J. S., Woolf T. M., Bumcrot D. A., Mahanthappa K., Pang K. Sonic hedgehog promotes the survival of specific CNS neuron populations and protects these cells from toxic insultin vitro. J. Neurosci. 17:1997;5891-5899.
-
(1997)
J. Neurosci.
, vol.17
, pp. 5891-5899
-
-
Miao, N.1
Wang, M.2
Ott, J.A.3
D'Alessandro, J.S.4
Woolf, T.M.5
Bumcrot, D.A.6
Mahanthappa, K.7
Pang, K.8
-
78
-
-
0029952139
-
Toxicity and tolerability of recombinant human ciliary neurotrophic factor in patients with amyotrophic lateral sclerosis
-
Miller R. G., Bryan W. W., Dietz M. A., Munsat T. L., Petajan J. H., Smith S. A., Goodpasture J. C. Toxicity and tolerability of recombinant human ciliary neurotrophic factor in patients with amyotrophic lateral sclerosis. Neurology. 47:1996a;1329-1331.
-
(1996)
Neurology
, vol.47
, pp. 1329-1331
-
-
Miller, R.G.1
Bryan, W.W.2
Dietz, M.A.3
Munsat, T.L.4
Petajan, J.H.5
Smith, S.A.6
Goodpasture, J.C.7
-
79
-
-
9044219848
-
A placebo-controlled trial of recombinant human ciliary neurotrophic (rhCNTF) factor in amyotrophic lateral sclerosis. rhCNTF ALS Study Group
-
Miller R. G., Petajan J. H., Bryan W. W., Armon C., Barohn R. J., Goodpasture J. C., Hoagland R. J., Parry G. J., Ross M. A., Stromatt S. C. A placebo-controlled trial of recombinant human ciliary neurotrophic (rhCNTF) factor in amyotrophic lateral sclerosis. rhCNTF ALS Study Group. Ann. Neurol. 39:1996b;256-260.
-
(1996)
Ann. Neurol.
, vol.39
, pp. 256-260
-
-
Miller, R.G.1
Petajan, J.H.2
Bryan, W.W.3
Armon, C.4
Barohn, R.J.5
Goodpasture, J.C.6
Hoagland, R.J.7
Parry, G.J.8
Ross, M.A.9
Stromatt, S.C.10
-
80
-
-
0029039180
-
Evidence for multiple activators for stress-activated protein kinases/c-Jun amino-terminal kinases
-
Moriguchi T., Kawasaki H., Matsuda S., Gotoh Y., Nishida E. Evidence for multiple activators for stress-activated protein kinases/c-Jun amino-terminal kinases. J. Biol. Chem. 270:1995;12969-12972.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 12969-12972
-
-
Moriguchi, T.1
Kawasaki, H.2
Matsuda, S.3
Gotoh, Y.4
Nishida, E.5
-
81
-
-
0027955091
-
Production and characterization of recombinant rat brain-derived neurotrophic factor and neurotrophin-3 from insect cells
-
Negro A., Tavella A., Grandi C., Skaper S. D. Production and characterization of recombinant rat brain-derived neurotrophic factor and neurotrophin-3 from insect cells. J. Neurochem. 62:1994;471-478.
-
(1994)
J. Neurochem.
, vol.62
, pp. 471-478
-
-
Negro, A.1
Tavella, A.2
Grandi, C.3
Skaper, S.D.4
-
84
-
-
0026058318
-
Cell death during development of the nervous system
-
Oppenheim R. W. Cell death during development of the nervous system. Annu. Rev. Neurosci. 14:1991;451-501.
-
(1991)
Annu. Rev. Neurosci.
, vol.14
, pp. 451-501
-
-
Oppenheim, R.W.1
-
85
-
-
0026334203
-
The phosphorylation and activation of B-raf in PC12 cells stimulated by nerve growth factor
-
Oshima M., Sithanandam G., Rapp U., Guroff G. The phosphorylation and activation of B-raf in PC12 cells stimulated by nerve growth factor. J. Biol. Chem. 266:1993;23753-23760.
-
(1993)
J. Biol. Chem.
, vol.266
, pp. 23753-23760
-
-
Oshima, M.1
Sithanandam, G.2
Rapp, U.3
Guroff, G.4
-
86
-
-
0029082202
-
Deletion of a conserved juxtamembrane sequence in Trk abolishes NGF-promoted neuritogenesis
-
Peng X., Greene L., Kaplan D., Stephens R. Deletion of a conserved juxtamembrane sequence in Trk abolishes NGF-promoted neuritogenesis. Neuron. 15:1995;395-406.
-
(1995)
Neuron
, vol.15
, pp. 395-406
-
-
Peng, X.1
Greene, L.2
Kaplan, D.3
Stephens, R.4
-
87
-
-
0031028248
-
Intrathecal ciliary neurotrophic factor delivery for treatment of amyotrophic lateral sclerosis (phase I trial)
-
Penn R. D., Kroin J. S., York M. M., Cederbaum J. M. Intrathecal ciliary neurotrophic factor delivery for treatment of amyotrophic lateral sclerosis (phase I trial). Neurosurgery. 40:1997;94-99.
-
(1997)
Neurosurgery
, vol.40
, pp. 94-99
-
-
Penn, R.D.1
Kroin, J.S.2
York, M.M.3
Cederbaum, J.M.4
-
88
-
-
0030694175
-
Activated phosphatidylinositol 3-kinase and Akt kinase promote survival of superior cervical neurons
-
Philpott K. L., McCarthy M. J., Klippel A., Rubin L. L. Activated phosphatidylinositol 3-kinase and Akt kinase promote survival of superior cervical neurons. J. Cell Biol. 139:1997;809-815.
-
(1997)
J. Cell Biol.
, vol.139
, pp. 809-815
-
-
Philpott, K.L.1
McCarthy, M.J.2
Klippel, A.3
Rubin, L.L.4
-
89
-
-
0031428894
-
TGF-beta in the central nervous system: Potential roles in ischemic injury and neurodegenerative diseases
-
Pratt B. M., McPherson J. M. TGF-beta in the central nervous system: Potential roles in ischemic injury and neurodegenerative diseases. Cytokine Growth Factor Rev. 8:1997;267-292.
-
(1997)
Cytokine Growth Factor Rev.
, vol.8
, pp. 267-292
-
-
Pratt, B.M.1
McPherson, J.M.2
-
90
-
-
0028938420
-
Okadaic acid increases nerve growth factor secretion, mRNA stability, and gene transcription in primary cultures of cortical astrocytes
-
Pshenichkin S. P., Wise B. C. Okadaic acid increases nerve growth factor secretion, mRNA stability, and gene transcription in primary cultures of cortical astrocytes. J. Biol. Chem. 270:1995;5994-5999.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 5994-5999
-
-
Pshenichkin, S.P.1
Wise, B.C.2
-
92
-
-
0027395119
-
SNT, a differentiation-specific target of neurotrophic factor-induced tyrosine kinase activity in neurons and PC12 cells
-
Rabin S., Cleghorn V., Kaplan D. SNT, a differentiation-specific target of neurotrophic factor-induced tyrosine kinase activity in neurons and PC12 cells. Mol. Cell. Biol. 13:1993;2203-2213.
-
(1993)
Mol. Cell. Biol.
, vol.13
, pp. 2203-2213
-
-
Rabin, S.1
Cleghorn, V.2
Kaplan, D.3
-
93
-
-
0027237273
-
A dominant-negative mutant of raf blocks mitogen-activated protein kinase activation by growth factors and oncogenic p21ras
-
Schaap D., van der Wal J., Howe L. R., Marshall C. J., van Blitterswijk W. J. A dominant-negative mutant of raf blocks mitogen-activated protein kinase activation by growth factors and oncogenic p21ras. J. Biol. Chem. 268:1993;20232-20236.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 20232-20236
-
-
Schaap, D.1
Van Der Wal, J.2
Howe, L.R.3
Marshall, C.J.4
Van Blitterswijk, W.J.5
-
95
-
-
0025291340
-
Activin is a nerve cell survival molecule
-
Schubert D., Kimura H., LaCorbiere M., Vaughan J., Karr D., Fischer W. H. Activin is a nerve cell survival molecule. Nature. 344:1990;868-870.
-
(1990)
Nature
, vol.344
, pp. 868-870
-
-
Schubert, D.1
Kimura, H.2
Lacorbiere, M.3
Vaughan, J.4
Karr, D.5
Fischer, W.H.6
-
96
-
-
0029925683
-
Intracellular signaling pathways activated by neurotrophic factors
-
Segal R. A., Greenberg M. E. Intracellular signaling pathways activated by neurotrophic factors. Annu. Rev. Neurosci. 19:1996;463-489.
-
(1996)
Annu. Rev. Neurosci.
, vol.19
, pp. 463-489
-
-
Segal, R.A.1
Greenberg, M.E.2
-
97
-
-
0027731159
-
Intracranial infusion of purified nerve growth factor to an Alzheimer patient: The first attempt of a possible future treatment strategy
-
Seiger A., Nordberg A., von Holst H., Backman L., Ebendal T., Alafuzoff I., Amberla K., Hartvig P., Herlitz A., Lilja A. Intracranial infusion of purified nerve growth factor to an Alzheimer patient: The first attempt of a possible future treatment strategy. Behav. Brain Res. 57:1993;255-261.
-
(1993)
Behav. Brain Res.
, vol.57
, pp. 255-261
-
-
Seiger, A.1
Nordberg, A.2
Von Holst, H.3
Backman, L.4
Ebendal, T.5
Alafuzoff, I.6
Amberla, K.7
Hartvig, P.8
Herlitz, A.9
Lilja, A.10
-
98
-
-
0030753359
-
+
-
+. Dev. Brain Res. 101:1997;197-206.
-
(1997)
Dev. Brain Res.
, vol.101
, pp. 197-206
-
-
Shimoke, K.1
Kubo, T.2
Numakawa, T.3
Abiru, Y.4
Enokido, Y.5
Takei, N.6
Ikeuchi, T.7
Hatanaka, H.8
-
99
-
-
0031978372
-
Neurotrophins rescue cerebellar granule neurons from oxidative stress-mediated apoptotic death: Selective involvement of phosphatidylinositol 3-kinase and the mitogen-activated protein kinase pathway
-
Skaper S. D., Floreani M., Negro A., Facci L., Giusti P. Neurotrophins rescue cerebellar granule neurons from oxidative stress-mediated apoptotic death: Selective involvement of phosphatidylinositol 3-kinase and the mitogen-activated protein kinase pathway. J. Neurochem. 70:1998;1859-1868.
-
(1998)
J. Neurochem.
, vol.70
, pp. 1859-1868
-
-
Skaper, S.D.1
Floreani, M.2
Negro, A.3
Facci, L.4
Giusti, P.5
-
100
-
-
0028238769
-
Functions of the neurotrophins during nervous system development: What the knockouts are teaching us
-
Snider W. D. Functions of the neurotrophins during nervous system development: What the knockouts are teaching us. Cell. 77:1994;627-638.
-
(1994)
Cell
, vol.77
, pp. 627-638
-
-
Snider, W.D.1
-
101
-
-
0027328343
-
The alphas, betas, and kinases of cytokine receptor complexes
-
Stahl N., Yancopoulos G. D. The alphas, betas, and kinases of cytokine receptor complexes. Cell. 74:1993;587-590.
-
(1993)
Cell
, vol.74
, pp. 587-590
-
-
Stahl, N.1
Yancopoulos, G.D.2
-
102
-
-
0028149838
-
The tripartite CNTF receptor complex: Activation and signaling involves components shared with other cytokines
-
Stahl N., Yancopoulos G. D. The tripartite CNTF receptor complex: Activation and signaling involves components shared with other cytokines. J. Neurobiol. 25:1994;1454-1466.
-
(1994)
J. Neurobiol.
, vol.25
, pp. 1454-1466
-
-
Stahl, N.1
Yancopoulos, G.D.2
-
103
-
-
0030975605
-
Neurotrophic actions of nonimmunosuppressive analogues of immunosuppressive drugs FK506, rapamycin and cyclosporin A
-
Steiner J. P., Connolly M. A., Valentine H. L., Hamilton G. S., Dawson T. M., Hester L., Snyder S. H. Neurotrophic actions of nonimmunosuppressive analogues of immunosuppressive drugs FK506, rapamycin and cyclosporin A. Nature. Med. 3:1997a;421-428.
-
(1997)
Nature. Med.
, vol.3
, pp. 421-428
-
-
Steiner, J.P.1
Connolly, M.A.2
Valentine, H.L.3
Hamilton, G.S.4
Dawson, T.M.5
Hester, L.6
Snyder, S.H.7
-
104
-
-
0026673772
-
High brain densities of the immunophilin FKBP colocalized with calcineurin
-
Steiner J. P., Dawson T. M., Fotuhi M., Glatt C. E., Snowman A. M., Cohen N., Snyder S. H. High brain densities of the immunophilin FKBP colocalized with calcineurin. Nature. 358:1992;584-587.
-
(1992)
Nature
, vol.358
, pp. 584-587
-
-
Steiner, J.P.1
Dawson, T.M.2
Fotuhi, M.3
Glatt, C.E.4
Snowman, A.M.5
Cohen, N.6
Snyder, S.H.7
-
105
-
-
12644257556
-
Neurotrophic immunophilin ligands stimulate structural and functional recovery in neurodegenerative animal models
-
Steiner J. P., Hamilton G. S., Ross D. T., Valentine H. L., Guo H., Connolly M. A., Liang S., Ramsey C., Li J.-H. J., Huang W., Howorth P., Soni R., Fuller M., Sauer H., Nowotnik A. C., Suzdak P. D. Neurotrophic immunophilin ligands stimulate structural and functional recovery in neurodegenerative animal models. Proc. Natl. Acad. Sci. USA. 94:1997b;2019-2024.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 2019-2024
-
-
Steiner, J.P.1
Hamilton, G.S.2
Ross, D.T.3
Valentine, H.L.4
Guo, H.5
Connolly, M.A.6
Liang, S.7
Ramsey, C.8
Li J.-H., J.9
Huang, W.10
Howorth, P.11
Soni, R.12
Fuller, M.13
Sauer, H.14
Nowotnik, A.C.15
Suzdak, P.D.16
-
106
-
-
0025075302
-
Effect of a dominant inhibitory Ha-ras mutation on neuronal differentiation of PC12 cells
-
Szeberenyi J., Cai H., Cooper G. Effect of a dominant inhibitory Ha-ras mutation on neuronal differentiation of PC12 cells. Mol. Cell. Biol. 10:1990;5324-5332.
-
(1990)
Mol. Cell. Biol.
, vol.10
, pp. 5324-5332
-
-
Szeberenyi, J.1
Cai, H.2
Cooper, G.3
-
107
-
-
0029959555
-
The molecular biology of axon guidance
-
Tessier-Lavigne M., Goodman C. S. The molecular biology of axon guidance. Science. 274:1996;1123-1133.
-
(1996)
Science
, vol.274
, pp. 1123-1133
-
-
Tessier-Lavigne, M.1
Goodman, C.S.2
-
108
-
-
0028866230
-
Neurotrophins and neuronal plasticity
-
Thoenen H. Neurotrophins and neuronal plasticity. Science. 270:1995;593-598.
-
(1995)
Science
, vol.270
, pp. 593-598
-
-
Thoenen, H.1
-
109
-
-
0019071287
-
Physiology of nerve growth factor
-
Thoenen H., Barde Y.-A. Physiology of nerve growth factor. Physiol. Rev. 60:1980;1284-1335.
-
(1980)
Physiol. Rev.
, vol.60
, pp. 1284-1335
-
-
Thoenen, H.1
Barde, Y.-A.2
-
110
-
-
0031912461
-
Neurotrophic factors and the maldevelopmental hypothesis of schizophrenic psychoses. Review article
-
Thome J., Foley P., Riederer P. Neurotrophic factors and the maldevelopmental hypothesis of schizophrenic psychoses. Review article. J. Neural Transm. 105:1998;85-100.
-
(1998)
J. Neural Transm.
, vol.105
, pp. 85-100
-
-
Thome, J.1
Foley, P.2
Riederer, P.3
-
111
-
-
0032504007
-
A small, nonpeptidyl mimic of granulocyte-colony-stimulating factor
-
Tian S.-S., Lamb P., King A. G., Miller S. G., Kessler L., Leungo J. I., Averill L., Johnson R. K., Gleason J. G., Pelus L. M., Dillon S. B., Rosen J. A small, nonpeptidyl mimic of granulocyte-colony-stimulating factor. Science. 281:1998;257-259.
-
(1998)
Science
, vol.281
, pp. 257-259
-
-
Tian, S.-S.1
Lamb, P.2
King, A.G.3
Miller, S.G.4
Kessler, L.5
Leungo, J.I.6
Averill, L.7
Johnson, R.K.8
Gleason, J.G.9
Pelus, L.M.10
Dillon, S.B.11
Rosen, J.12
-
112
-
-
0031059921
-
Neurotrophic factors in action - New dogs and new tricks
-
Tolkovsky A. Neurotrophic factors in action - New dogs and new tricks. Trends Neurosci. 20:1997;1-3.
-
(1997)
Trends Neurosci.
, vol.20
, pp. 1-3
-
-
Tolkovsky, A.1
-
113
-
-
0030786344
-
Mitogen-activated kinase kinase 7 is an activator of the c-Jun amino terminal kinase
-
Tournier C., Whitmarsh A. J., Cavanagh J., Barrett T., Davis R. J. Mitogen-activated kinase kinase 7 is an activator of the c-Jun amino terminal kinase. Proc. Natl. Acad. Sci. USA. 94:1997;7337-7342.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 7337-7342
-
-
Tournier, C.1
Whitmarsh, A.J.2
Cavanagh, J.3
Barrett, T.4
Davis, R.J.5
-
114
-
-
0029125589
-
Activation of p44 and p42 MAP kinases is not essential for the survival of rat sympathetic neurons
-
Virdee K., Tolkovsky A. M. Activation of p44 and p42 MAP kinases is not essential for the survival of rat sympathetic neurons. Eur. J. Neurosci. 7:1995;2159-2169.
-
(1995)
Eur. J. Neurosci.
, vol.7
, pp. 2159-2169
-
-
Virdee, K.1
Tolkovsky, A.M.2
-
115
-
-
0029800940
-
Inhibition of p42 and p44 mitogen-activated protein kinase activity by PD98059 does not suppress nerve growth factor-induced survival of sympathetic neurones
-
Virdee K., Tolkovsky A. M. Inhibition of p42 and p44 mitogen-activated protein kinase activity by PD98059 does not suppress nerve growth factor-induced survival of sympathetic neurones. J. Neurochem. 67:1996;1801-1805.
-
(1996)
J. Neurochem.
, vol.67
, pp. 1801-1805
-
-
Virdee, K.1
Tolkovsky, A.M.2
-
116
-
-
0030751556
-
Comparison between the timing of JNK activation, c-Jun phosphorylation, and onset of death commitment in sympathetic neurons
-
Virdee K., Bannister A. J., Hunt S. P., Tolkovsky A. M. Comparison between the timing of JNK activation, c-Jun phosphorylation, and onset of death commitment in sympathetic neurons. J. Neurochem. 69:1997;550-561.
-
(1997)
J. Neurochem.
, vol.69
, pp. 550-561
-
-
Virdee, K.1
Bannister, A.J.2
Hunt, S.P.3
Tolkovsky, A.M.4
-
117
-
-
0029120950
-
Loss of neurofibromin results in neurotrophin-independent survival of embryonic sensory and sympathetic neurons
-
Vogel K. S., Brannan C. I., Jenkins N. A., Copeland N. G., Parada L. F. Loss of neurofibromin results in neurotrophin-independent survival of embryonic sensory and sympathetic neurons. Cell. 82:1995;733-742.
-
(1995)
Cell
, vol.82
, pp. 733-742
-
-
Vogel, K.S.1
Brannan, C.I.2
Jenkins, N.A.3
Copeland, N.G.4
Parada, L.F.5
-
118
-
-
0024504895
-
Novel neurotrophic factors, receptors, and oncogenes
-
Walicke P. A. Novel neurotrophic factors, receptors, and oncogenes. Annu. Rev. Neurosci. 12:1989;103-126.
-
(1989)
Annu. Rev. Neurosci.
, vol.12
, pp. 103-126
-
-
Walicke, P.A.1
-
119
-
-
0031439129
-
Neural cell adhesion molecules of the immunoglobulin superfamily: Role in axon growth and guidance
-
Walsh F. S., Doherty P. Neural cell adhesion molecules of the immunoglobulin superfamily: Role in axon growth and guidance. Annu. Rev. Cell. Dev. Biol. 13:1997;425-456.
-
(1997)
Annu. Rev. Cell. Dev. Biol.
, vol.13
, pp. 425-456
-
-
Walsh, F.S.1
Doherty, P.2
-
120
-
-
0032493859
-
Switching signals on or off by receptor dimerization
-
Weiss A., Schlessinger J. Switching signals on or off by receptor dimerization. Cell. 94:1998;277-280.
-
(1998)
Cell
, vol.94
, pp. 277-280
-
-
Weiss, A.1
Schlessinger, J.2
-
121
-
-
0030437247
-
Glial cell line-derived neurotrophic factor sustains axotomized basal forebrain cholinergic neurons in vivo: Dose-response comparison to nerve growth factor and brain-derived neurotrophic factor
-
Williams L. R., Inouye G., Cummins V., Pelleymounter M. A. Glial cell line-derived neurotrophic factor sustains axotomized basal forebrain cholinergic neurons in vivo: Dose-response comparison to nerve growth factor and brain-derived neurotrophic factor. J. Pharmacol. Exp. Ther. 277:1997;1140-1151.
-
(1997)
J. Pharmacol. Exp. Ther.
, vol.277
, pp. 1140-1151
-
-
Williams, L.R.1
Inouye, G.2
Cummins, V.3
Pelleymounter, M.A.4
-
122
-
-
0027164311
-
The cytoplasmic raf oncogene induces a neuronal phenotype in PC12 cells: A potential role for cellular rat kinases in neuronal growth factor signal transduction
-
Wood K. W., Qi H., D'Arcangelo G., Armstrong R. C., Roberts T. M., Halegoua S. The cytoplasmic raf oncogene induces a neuronal phenotype in PC12 cells: A potential role for cellular rat kinases in neuronal growth factor signal transduction. Proc. Natl. Acad. Sci. USA. 90:1993;5016-5020.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 5016-5020
-
-
Wood, K.W.1
Qi, H.2
D'Arcangelo, G.3
Armstrong, R.C.4
Roberts, T.M.5
Halegoua, S.6
-
123
-
-
0026523559
-
Ras mediates nerve growth factor receptor modulation of three signal-transduction protein kinases: MAP kinase, Raf-1, and RSK
-
Wood K. W., Sarnecki C., Roberts T. M., Blenis J. Ras mediates nerve growth factor receptor modulation of three signal-transduction protein kinases: MAP kinase, Raf-1, and RSK. Cell. 68:1992;1041-1050.
-
(1992)
Cell
, vol.68
, pp. 1041-1050
-
-
Wood, K.W.1
Sarnecki, C.2
Roberts, T.M.3
Blenis, J.4
-
124
-
-
0028880006
-
Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis
-
Xia Z., Dickens M., Raingeaud J., Davis R. J., Greenberg M. E. Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis. Science. 270:1995;1326-1331.
-
(1995)
Science
, vol.270
, pp. 1326-1331
-
-
Xia, Z.1
Dickens, M.2
Raingeaud, J.3
Davis, R.J.4
Greenberg, M.E.5
-
125
-
-
0031081164
-
Orally active NGF synthesis stimulators: Potential therapeutic agents in Alzheimer's disease
-
Yamada K., Nitta A., Hasegawa T., Fuji K., Hiramatsu M., Kameyama T., Furukawa Y., Hayashi K., Nabeshima T. Orally active NGF synthesis stimulators: Potential therapeutic agents in Alzheimer's disease. Behav. Brain Res. 83:1997;117-122.
-
(1997)
Behav. Brain Res.
, vol.83
, pp. 117-122
-
-
Yamada, K.1
Nitta, A.2
Hasegawa, T.3
Fuji, K.4
Hiramatsu, M.5
Kameyama, T.6
Furukawa, Y.7
Hayashi, K.8
Nabeshima, T.9
-
126
-
-
0028963084
-
Requirement for phosphatidylinositol 3-kinase in the prevention of apoptosis by nerve growth factor
-
Yao R., Cooper G. M. Requirement for phosphatidylinositol 3-kinase in the prevention of apoptosis by nerve growth factor. Science. 267:1995;2003-2006.
-
(1995)
Science
, vol.267
, pp. 2003-2006
-
-
Yao, R.1
Cooper, G.M.2
-
127
-
-
0029812881
-
Therapeutic potential of neurotrophic factors for neurological disorders
-
Yuen E. C., Mobley W. C. Therapeutic potential of neurotrophic factors for neurological disorders. Ann. Neurol. 40:1996;346-354.
-
(1996)
Ann. Neurol.
, vol.40
, pp. 346-354
-
-
Yuen, E.C.1
Mobley, W.C.2
|