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Volumn 106, Issue 2, 1996, Pages 218-229

Preferential elimination of CD28+ T cells in systemic lupus erythematosus (SLE) and the relation with activation-induced apoptosis

Author keywords

apoptosis; CD28; systemic lupus erythematosus; T cell activation

Indexed keywords

CD28 ANTIGEN; CD3 ANTIGEN;

EID: 0029841476     PISSN: 00099104     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2249.1996.d01-849.x     Document Type: Article
Times cited : (68)

References (66)
  • 1
    • 0025339511 scopus 로고
    • A cell culture model for T lymphocyte clonal anergy
    • Schwartz RH. A cell culture model for T lymphocyte clonal anergy. Science 1990; 48:1349 56.
    • (1990) Science , vol.48 , pp. 1349-1356
    • Schwartz, R.H.1
  • 2
    • 0026537347 scopus 로고
    • CD28 mediated signaling costimulates murine T cells and prevents induction of anergy in T cell clones
    • Harding FA, McArthur JG, Gross JA et al. CD28 mediated signaling costimulates murine T cells and prevents induction of anergy in T cell clones. Nature 1992; 356:607-9.
    • (1992) Nature , vol.356 , pp. 607-609
    • Harding, F.A.1    McArthur, J.G.2    Gross, J.A.3
  • 3
    • 0025965167 scopus 로고
    • Receptor-stimulated death pathway is opened by antigen in mature T cells
    • Russell JH, White CL, Loh DY et al. Receptor-stimulated death pathway is opened by antigen in mature T cells. Proc Natl Acad Sci USA 1991; 88:2151 5.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 2151-2155
    • Russell, J.H.1    White, C.L.2    Loh, D.Y.3
  • 4
    • 0027264109 scopus 로고
    • Religation of the T cell receptor after primary activation of mature T cells inhibits proliferation and induces apoptotic cell death
    • Radvanyi LG, Mills GB, Miller RG. Religation of the T cell receptor after primary activation of mature T cells inhibits proliferation and induces apoptotic cell death. J Immunol 1993; 150: 5704-15.
    • (1993) J Immunol , vol.150 , pp. 5704-5715
    • Radvanyi, L.G.1    Mills, G.B.2    Miller, R.G.3
  • 5
    • 0027315279 scopus 로고
    • Induction of activation-driven death (apoptosis) in activated but not resting peripheral blood T cells
    • Wesselborg S, Janssen O, Kabelitz D. Induction of activation-driven death (apoptosis) in activated but not resting peripheral blood T cells. J Immunol 1993; 150:4338 45.
    • (1993) J Immunol , vol.150 , pp. 4338-4345
    • Wesselborg, S.1    Janssen, O.2    Kabelitz, D.3
  • 6
    • 0024511201 scopus 로고
    • An accessory cell-derived costimulatory signal acts independently of protein kinase C activation to allow T cell proliferation and prevent the induction of unresponsiveness
    • Mueller DL, Jenkins MK, Schwartz RH. An accessory cell-derived costimulatory signal acts independently of protein kinase C activation to allow T cell proliferation and prevent the induction of unresponsiveness. J Immunol 1989; 142:2617 28.
    • (1989) J Immunol , vol.142 , pp. 2617-2628
    • Mueller, D.L.1    Jenkins, M.K.2    Schwartz, R.H.3
  • 7
    • 0024444165 scopus 로고
    • B7, a new member of the Ig superfamily with unique expression on activated and neoplastic B cells
    • Freeman GJ, Freedman AS, Segil JM et al. B7, a new member of the Ig superfamily with unique expression on activated and neoplastic B cells. J Immunol 1989; 143:2714 22.
    • (1989) J Immunol , vol.143 , pp. 2714-2722
    • Freeman, G.J.1    Freedman, A.S.2    Segil, J.M.3
  • 8
    • 0023636171 scopus 로고
    • B7, a B cell-restricted antigen that identities preactivated B cells
    • Freedman AS, Freeman G, Horowitz JC et al. B7, a B cell-restricted antigen that identities preactivated B cells. J Immunol 1987; 139: 3260 7.
    • (1987) J Immunol , vol.139 , pp. 3260-3267
    • Freedman, A.S.1    Freeman, G.2    Horowitz, J.C.3
  • 9
    • 0027362823 scopus 로고
    • B70 antigen is a second ligand for CTLA-4 and CD28
    • Azuma M, Ito D, Yagita H et al. B70 antigen is a second ligand for CTLA-4 and CD28. Nature 1993; 366:76-79.
    • (1993) Nature , vol.366 , pp. 76-79
    • Azuma, M.1    Ito, D.2    Yagita, H.3
  • 10
    • 0027767762 scopus 로고
    • Cloning of B7-2; a CTLA-4 counter-receptor that costimulates human T cell proliferation
    • Freeman GJ, Gribben JG, Boussiotis VA et al. Cloning of B7-2; a CTLA-4 counter-receptor that costimulates human T cell proliferation. Science 1993; 262:909-11.
    • (1993) Science , vol.262 , pp. 909-911
    • Freeman, G.J.1    Gribben, J.G.2    Boussiotis, V.A.3
  • 11
    • 0026518418 scopus 로고
    • CD28 interaction with B7 co-stimulates primary allogeneic proliferative responses and cytotoxicity mediated by small, resting T lymphocytes
    • Azuma M, Cayabyab M, Buck D et al. CD28 interaction with B7 co-stimulates primary allogeneic proliferative responses and cytotoxicity mediated by small, resting T lymphocytes. J Exp Med 1992; 175:353-60.
    • (1992) J Exp Med , vol.175 , pp. 353-360
    • Azuma, M.1    Cayabyab, M.2    Buck, D.3
  • 12
    • 0028819315 scopus 로고
    • CDSO (B7) and CD86 (B70) provide similar costimulatory signals for T cell proliferation, cytokine production and generation of cytotoxic T lymphocytes
    • Lanier LL, O'Fallon S, Somoza C et al. CDSO (B7) and CD86 (B70) provide similar costimulatory signals for T cell proliferation, cytokine production and generation of cytotoxic T lymphocytes. J Immunol 1995; 154:97 105.
    • (1995) J Immunol , vol.154 , pp. 97-105
    • Lanier, L.L.1    O'Fallon, S.2    Somoza, C.3
  • 13
    • 0019271427 scopus 로고
    • Monoclonal antibodies identifying a novel T-cell antigen and la antigens of human lymphocytes
    • Hansen JA, Martin PJ, Nowinski RC. Monoclonal antibodies identifying a novel T-cell antigen and la antigens of human lymphocytes. Immunogenetics 1980; 10:247 60.
    • (1980) Immunogenetics , vol.10 , pp. 247-260
    • Hansen, J.A.1    Martin, P.J.2    Nowinski, R.C.3
  • 14
    • 0022397357 scopus 로고
    • Monoclonal antibody 9·3 and anti-CD11 antibodies define reciprocal subsets of lymphocytes
    • Yamada H, Martin PJ, Braun MP et al. Monoclonal antibody 9·3 and anti-CD11 antibodies define reciprocal subsets of lymphocytes. Eur J Immunol 1985; 15:1164 8.
    • (1985) Eur J Immunol , vol.15 , pp. 1164-1168
    • Yamada, H.1    Martin, P.J.2    Braun, M.P.3
  • 15
    • 0027252136 scopus 로고
    • CD28 T lymphocytes: Antigenic and functional properties
    • Azuma M, Phillips JH, Lanier LL. CD28 T lymphocytes: antigenic and functional properties. J Immunol 1993; 150:1147 59.
    • (1993) J Immunol , vol.150 , pp. 1147-1159
    • Azuma, M.1    Phillips, J.H.2    Lanier, L.L.3
  • 16
    • 0024444557 scopus 로고
    • + cells with a limited alloreactive T cell receptor repertoire
    • + cells with a limited alloreactive T cell receptor repertoire. J Immunol 1989; 143:2783 9.
    • (1989) J Immunol , vol.143 , pp. 2783-2789
    • Morishita, Y.1    Sao, H.2    Hansen, J.A.3
  • 18
    • 0026582064 scopus 로고
    • Sequential paraformaldehyde and methanol fixation for simultaneous flow cytometric analysis of DNA, cell surface proteins, and intracellular proteins
    • Pollice AA, McCoy JPJ, Shackney SE et al. Sequential paraformaldehyde and methanol fixation for simultaneous flow cytometric analysis of DNA, cell surface proteins, and intracellular proteins. Cytometry 1992; 13:432 44.
    • (1992) Cytometry , vol.13 , pp. 432-444
    • Pollice, A.A.1    McCoy, J.P.J.2    Shackney, S.E.3
  • 19
  • 20
    • 0025912608 scopus 로고
    • + lymphocytes from bone marrow transplantated patients inhibits cell mediated cytolysis
    • + lymphocytes from bone marrow transplantated patients inhibits cell mediated cytolysis. Blood 1991; 77: 2237 41.
    • (1991) Blood , vol.77 , pp. 2237-2241
    • Autran, B.1    Leblond, V.2    Sadat-Soeti, B.3
  • 21
    • 0022476611 scopus 로고    scopus 로고
    • + suppressor lymphocytes in the blood of long-term surviving patients after allogeneic bone marrow transplantation
    • + suppressor lymphocytes in the blood of long-term surviving patients after allogeneic bone marrow transplantation. J Immunol 1996; 137: 2180 9.
    • (1996) J Immunol , vol.137 , pp. 2180-2189
    • Leroy, E.1    Calvo, C.F.2    Divine, M.3
  • 22
    • 0343670600 scopus 로고
    • Anomalous interaction of the acetylcholine receptor protein with the nonionic detergent Triton X-114
    • Maher PA, Singer SJ. Anomalous interaction of the acetylcholine receptor protein with the nonionic detergent Triton X-114. Proc Natl Acad Sci USA 1995; 82:958 62.
    • (1995) Proc Natl Acad Sci USA , vol.82 , pp. 958-962
    • Maher, P.A.1    Singer, S.J.2
  • 23
    • 0026726421 scopus 로고
    • Expression of perforin and cytolytic potential of human peripheral blood lymphocyte subpopulations
    • Nakata M, Kawasaki A, Azuma M et al. Expression of perforin and cytolytic potential of human peripheral blood lymphocyte subpopulations. Int Immunol 1992; 4:1049 54.
    • (1992) Int Immunol , vol.4 , pp. 1049-1054
    • Nakata, M.1    Kawasaki, A.2    Azuma, M.3
  • 24
    • 0028218419 scopus 로고
    • Lymphocytotoxic antibodies in SLE: A review of the literature
    • Osman C, Swaak AJG. Lymphocytotoxic antibodies in SLE: a review of the literature. Clin Rheumatol 1994; 13:21 27.
    • (1994) Clin Rheumatol , vol.13 , pp. 21-27
    • Osman, C.1    Swaak, A.J.G.2
  • 25
    • 0028909197 scopus 로고
    • Fas ligand mediates activation-induced cell death in human T lymphocytes
    • Alderson MR, Tough TW, Davis-Smith T et al. Fas ligand mediates activation-induced cell death in human T lymphocytes. J Exp Med 1993; 181:71 77.
    • (1993) J Exp Med , vol.181 , pp. 71-77
    • Alderson, M.R.1    Tough, T.W.2    Davis-Smith, T.3
  • 26
    • 0028893078 scopus 로고
    • Fas (CD95)/FasL interactions required for programmed cell death after T-cell activation
    • Ju ST, Panka DJ, Cui H et al. Fas (CD95)/FasL interactions required for programmed cell death after T-cell activation. Nature 1995; 373:444-8.
    • (1995) Nature , vol.373 , pp. 444-448
    • Ju, S.T.1    Panka, D.J.2    Cui, H.3
  • 27
    • 0028206650 scopus 로고
    • Autoimmunity and apoptosis
    • Tan EM. Autoimmunity and apoptosis. J Exp Med 1994; 179:1083 6.
    • (1994) J Exp Med , vol.179 , pp. 1083-1086
    • Tan, E.M.1
  • 28
    • 0020436689 scopus 로고
    • The 1982 revised criteria for the classification of systemic lupus erythematosus
    • Tan EM, Cohen A, Fries JF et al. The 1982 revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum 1982; 25:1271-7.
    • (1982) Arthritis Rheum , vol.25 , pp. 1271-1277
    • Tan, E.M.1    Cohen, A.2    Fries, J.F.3
  • 29
    • 0028095477 scopus 로고
    • Apoptotic signaling through CD95 (Fas/Apo-1) activates an acidic sphingomyelinase
    • Cifone MG, de Maniai R, Roncaioli P et al. Apoptotic signaling through CD95 (Fas/Apo-1) activates an acidic sphingomyelinase. J Exp Med 1994; 177:1547 52.
    • (1994) J Exp Med , vol.177 , pp. 1547-1552
    • Cifone, M.G.1    De Maniai, R.2    Roncaioli, P.3
  • 32
    • 0020527852 scopus 로고
    • T lymphocyte subsets in systemic lupus erythematosus
    • Bakke AC, Kirkland PA, Kitridou RC et al. T lymphocyte subsets in systemic lupus erythematosus. Arthritis Rheum 1983; 26: 745 50.
    • (1983) Arthritis Rheum , vol.26 , pp. 745-750
    • Bakke, A.C.1    Kirkland, P.A.2    Kitridou, R.C.3
  • 33
    • 0002645277 scopus 로고
    • T lymphocyte, cytokine, and immune regulation in systemic lupus erythematosus
    • Wallace DJ, Hahn BH, eds. London: Lea & Febiger
    • Horwitz DA, Stohl W, T lymphocyte, cytokine, and immune regulation in systemic lupus erythematosus. In: Wallace DJ, Hahn BH, eds. Dubois' lupus erythematosus, 4th edn. London: Lea & Febiger, 1993:83 96.
    • (1993) Dubois' Lupus Erythematosus, 4th Edn. , pp. 83-96
    • Horwitz, D.A.1    Stohl, W.2
  • 34
    • 0028330345 scopus 로고
    • Accelerated in vitro apoptosis of lymphocytes from patients with systemic lupus erythematosus
    • Emlen W, Niebur J, Kadera R. Accelerated in vitro apoptosis of lymphocytes from patients with systemic lupus erythematosus. J Immunol 1994; 152:3685 92.
    • (1994) J Immunol , vol.152 , pp. 3685-3692
    • Emlen, W.1    Niebur, J.2    Kadera, R.3
  • 35
    • 0025726216 scopus 로고
    • A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry
    • Nieoletti I, Migliorati G, Paglieei MC et al. A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry. J Immunol Methods 1941; 139:271 9.
    • (1941) J Immunol Methods , vol.139 , pp. 271-279
    • Nieoletti, I.1    Migliorati, G.2    Paglieei, M.C.3
  • 36
    • 0028911126 scopus 로고
    • Up-regulated expression of Fas antigen (CD95) by peripheral naive and memory T cell subsets in patients with systemic lupus erythematosus (SLE): A possible mechamism for lymphopenia
    • Amasaki Y, Kobayashi S, Takeda T et al. Up-regulated expression of Fas antigen (CD95) by peripheral naive and memory T cell subsets in patients with systemic lupus erythematosus (SLE): a possible mechamism for lymphopenia. Clin Exp Immunol 1995; 99:245 50.
    • (1995) Clin Exp Immunol , vol.99 , pp. 245-250
    • Amasaki, Y.1    Kobayashi, S.2    Takeda, T.3
  • 37
    • 0028329009 scopus 로고
    • The apoptosis-1/Fas protein in human systemic lupus erythematosus
    • Mysler E, Bini P, Drappa J et al. The apoptosis-1/Fas protein in human systemic lupus erythematosus. J Clin Invest 1994; 93:1029 34.
    • (1994) J Clin Invest , vol.93 , pp. 1029-1034
    • Mysler, E.1    Bini, P.2    Drappa, J.3
  • 38
    • 0027282044 scopus 로고
    • Bcl-x, a bcl-2-related gene that functions as a dominant regular of apoptotic cell death
    • Boise LH, Ding L, Lindsten T et al. bcl-x, a bcl-2-related gene that functions as a dominant regular of apoptotic cell death. Cell 1993; 74:597 608.
    • (1993) Cell , vol.74 , pp. 597-608
    • Boise, L.H.1    Ding, L.2    Lindsten, T.3
  • 40
    • 0028295331 scopus 로고
    • Lymphocyte activation in HIV-1 infection. II. Functional defects of CD28 T cells
    • Borthwick NJ, Bofill M, Gombert WM et al. Lymphocyte activation in HIV-1 infection. II. Functional defects of CD28 T cells. AIDS 1994; 8:431 41.
    • (1994) AIDS , vol.8 , pp. 431-441
    • Borthwick, N.J.1    Bofill, M.2    Gombert, W.M.3
  • 42
    • 0343111252 scopus 로고
    • B cell abnormalities characteristic of systemic lupus erythematosus
    • Wallace DJ, Hahn BH, eds. London: Lea & Febiger
    • Klinman DM. B cell abnormalities characteristic of systemic lupus erythematosus. In: Wallace DJ, Hahn BH, eds. Dubois' lupus erythematosus, 4th edn. London: Lea & Febiger, 1993:77 82.
    • (1993) Dubois' Lupus Erythematosus, 4th Edn. , pp. 77-82
    • Klinman, D.M.1
  • 43
    • 0027372258 scopus 로고
    • B-cell and T-cell function in systemic lupus erythematosus
    • Via CS, Handwerger BS. B-cell and T-cell function in systemic lupus erythematosus. Curr Opin Rheumatol 1993; 5:570 4.
    • (1993) Curr Opin Rheumatol , vol.5 , pp. 570-574
    • Via, C.S.1    Handwerger, B.S.2
  • 44
    • 0028238287 scopus 로고
    • B7/BB1 provides an important costimulatory signal for CD3-mediated T lymphocyte proliferation in patients with systemic lupus eythematosus (SLE)
    • Sfikakis PP, Oglesby R, Sfikakis P et al. B7/BB1 provides an important costimulatory signal for CD3-mediated T lymphocyte proliferation in patients with systemic lupus eythematosus (SLE). Clin J Immunol 1994; 96:8 14.
    • (1994) Clin J Immunol , vol.96 , pp. 8-14
    • Sfikakis, P.P.1    Oglesby, R.2    Sfikakis, P.3
  • 45
    • 0025021762 scopus 로고
    • + cylotoxic and suppressor T cell clones
    • + cylotoxic and suppressor T cell clones. J Immunol 1990; 144:32 40.
    • (1990) J Immunol , vol.144 , pp. 32-40
    • Koide, J.1    Engleman, E.G.2
  • 46
    • 0028020329 scopus 로고
    • Effect of CD28 antibody on T cells from patients with systemic lupus erythematosus
    • Alvarado C, Alcocer-Varela J, Llorente L et al. Effect of CD28 antibody on T cells from patients with systemic lupus erythematosus. J Autoimmun 1994; 7:763 73.
    • (1994) J Autoimmun , vol.7 , pp. 763-773
    • Alvarado, C.1    Alcocer-Varela, J.2    Llorente, L.3
  • 47
    • 0028924414 scopus 로고
    • CD28 expression on T cell subsets in vivo and CD28-mediated T cell response in vitro in patients with rheumatoid arthritis
    • Sfikakis PP, Zografou A, Viglis V et al. CD28 expression on T cell subsets in vivo and CD28-mediated T cell response in vitro in patients with rheumatoid arthritis. Arthritis Rheum 1995; 38:649 54.
    • (1995) Arthritis Rheum , vol.38 , pp. 649-654
    • Sfikakis, P.P.1    Zografou, A.2    Viglis, V.3
  • 48
    • 0027166048 scopus 로고
    • Bcl-2 heterodimerizes in vivo with a conserved homolog, bax, that accelerates programed cell death
    • Oltvai ZN, Milliman CL, Korsmeyer SJ. Bcl-2 heterodimerizes in vivo with a conserved homolog, bax, that accelerates programed cell death. Cell 1993; 74:609 19.
    • (1993) Cell , vol.74 , pp. 609-619
    • Oltvai, Z.N.1    Milliman, C.L.2    Korsmeyer, S.J.3
  • 49
    • 0027161158 scopus 로고
    • Effect of bcl-2 on Fas antigen-mediated cell death
    • Itoh N, Tsujimoto Y, Nagata S. Effect of bcl-2 on Fas antigen-mediated cell death. J Immunol 1993; 151:621 7.
    • (1993) J Immunol , vol.151 , pp. 621-627
    • Itoh, N.1    Tsujimoto, Y.2    Nagata, S.3
  • 50
    • 0026568919 scopus 로고
    • Lymphocyte proliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis
    • Watanabe-Fukunaga R, Brannan CI, Copeland NG et al. Lymphocyte proliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis. Nature 1992; 356:314 7.
    • (1992) Nature , vol.356 , pp. 314-317
    • Watanabe-Fukunaga, R.1    Brannan, C.I.2    Copeland, N.G.3
  • 51
    • 0026487088 scopus 로고
    • The Ipr and gld genes in systemic autoimmunity: Life and death in the Fas lane
    • Cohen PL, Eisenberg RA. The Ipr and gld genes in systemic autoimmunity: life and death in the Fas lane. Immunol Today 1992; 13:427 8.
    • (1992) Immunol Today , vol.13 , pp. 427-428
    • Cohen, P.L.1    Eisenberg, R.A.2
  • 52
    • 0026497684 scopus 로고
    • Differential expression of apoptosis-related Fas antigen on lymphocyte subpopulations in human peripheral blood
    • Miyawaki T, Uehara T, Nibu R et al. Differential expression of apoptosis-related Fas antigen on lymphocyte subpopulations in human peripheral blood. J Immunol 1992; 149:3753 8.
    • (1992) J Immunol , vol.149 , pp. 3753-3758
    • Miyawaki, T.1    Uehara, T.2    Nibu, R.3
  • 53
    • 0026524523 scopus 로고
    • DNA fragmentation and cell death is selectively triggered in activated human lymphocytes by Fas antigen engagement
    • Owen-Schaub LB, Yonehara S, Crump III WL et al. DNA fragmentation and cell death is selectively triggered in activated human lymphocytes by Fas antigen engagement. Cell Immunol 1992; 140: 197 205.
    • (1992) Cell Immunol , vol.140 , pp. 197-205
    • Owen-Schaub, L.B.1    Yonehara, S.2    Crump III, W.L.3
  • 54
    • 0027183703 scopus 로고
    • Activation interferes with the APO-1 pathway in mature human T cells
    • Klas C, Debatin K-M, Jonker RR et al. Activation interferes with the APO-1 pathway in mature human T cells. Int Immunol 1993; 5:625 30.
    • (1993) Int Immunol , vol.5 , pp. 625-630
    • Klas, C.1    Debatin, K.-M.2    Jonker, R.R.3
  • 55
    • 0028053599 scopus 로고
    • Human Fas ligand: Gene structure, ehromosomal location and species specificity
    • Takahashi T, Tanaka M, Inazuwa J et al. Human Fas ligand: gene structure, ehromosomal location and species specificity. Int Immunol 1994; 6:1567 74.
    • (1994) Int Immunol , vol.6 , pp. 1567-1574
    • Takahashi, T.1    Tanaka, M.2    Inazuwa, J.3
  • 56
    • 0028804857 scopus 로고
    • Metalloproteinase-mediated release of human Fas ligand
    • Kayagaki N, Kawasaki A, Ebata T et al. Metalloproteinase-mediated release of human Fas ligand. J Exp Med 1995; 182:1777 82.
    • (1995) J Exp Med , vol.182 , pp. 1777-1782
    • Kayagaki, N.1    Kawasaki, A.2    Ebata, T.3
  • 57
    • 0029163387 scopus 로고
    • CD28 costimulation can promote T cell survival by enhancing the expression of bcl-xL
    • Boise LH, Minn AJ, Noel PJ et al. CD28 costimulation can promote T cell survival by enhancing the expression of bcl-xL. Immunity 1995; 3:87 98.
    • (1995) Immunity , vol.3 , pp. 87-98
    • Boise, L.H.1    Minn, A.J.2    Noel, P.J.3
  • 58
    • 0029036715 scopus 로고
    • CD28 signals through acidic sphingomyelinase
    • Boucher L-M, Wiegmann K, Fütterer A et al. CD28 signals through acidic sphingomyelinase. J Exp Med 1995; 181:2059-68.
    • (1995) J Exp Med , vol.181 , pp. 2059-2068
    • Boucher, L.-M.1    Wiegmann, K.2    Fütterer, A.3
  • 59
    • 0029035315 scopus 로고
    • Sphingomyelin-ceramid turnover in CD28 costimulatory signaling
    • Chan G, Ochi A. Sphingomyelin-ceramid turnover in CD28 costimulatory signaling. Eur J Immunol 1995; 25:1999 2004.
    • (1995) Eur J Immunol , vol.25 , pp. 1999-2004
    • Chan, G.1    Ochi, A.2
  • 60
    • 0028287960 scopus 로고
    • Ionizing radiation acts on cellular membranes to generate ceramide and initiate apoptosis
    • Haimovitz-Friedman A, Kan C-C, Ehleiter D et al. Ionizing radiation acts on cellular membranes to generate ceramide and initiate apoptosis. J Exp Med 1994; 180:525-35.
    • (1994) J Exp Med , vol.180 , pp. 525-535
    • Haimovitz-Friedman, A.1    Kan, C.-C.2    Ehleiter, D.3
  • 61
    • 0028964917 scopus 로고
    • Fas-induced apoptosis is mediated via a ceramid-initiated RAS signaling pathway
    • Gulbins E, Bissonnette R, Mahboubi A et al. Fas-induced apoptosis is mediated via a ceramid-initiated RAS signaling pathway. Immunity 1995; 2:341 51.
    • (1995) Immunity , vol.2 , pp. 341-351
    • Gulbins, E.1    Bissonnette, R.2    Mahboubi, A.3
  • 63
    • 0029120245 scopus 로고
    • CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation
    • Klummel MF, Allison JP. CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation. J Exp Med 1995; 182:459 65.
    • (1995) J Exp Med , vol.182 , pp. 459-465
    • Klummel, M.F.1    Allison, J.P.2
  • 64
    • 0028484545 scopus 로고
    • CTLA-4 can function as a negative regulator of T cell activation
    • Walunus TL, Lenshow DJ, Bakker CY et al. CTLA-4 can function as a negative regulator of T cell activation. Immunity 1994; 1:405 13.
    • (1994) Immunity , vol.1 , pp. 405-413
    • Walunus, T.L.1    Lenshow, D.J.2    Bakker, C.Y.3
  • 65
    • 0028791059 scopus 로고
    • Lymphoproliferative disorders with early lethality in mice deficient in Ctla-4
    • Waterhouse P, Penninger JM, Timms E et al. Lymphoproliferative disorders with early lethality in mice deficient in Ctla-4. Science 1995; 270:985 8.
    • (1995) Science , vol.270 , pp. 985-988
    • Waterhouse, P.1    Penninger, J.M.2    Timms, E.3
  • 66
    • 0028867420 scopus 로고
    • Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4
    • Tivol EA, Borriello F, Schweitzer N et al. Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4. Immunity 1995; 3:541-7.
    • (1995) Immunity , vol.3 , pp. 541-547
    • Tivol, E.A.1    Borriello, F.2    Schweitzer, N.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.