-
1
-
-
0024358929
-
Signal transmission by the insulin-like growth factors
-
Czech MP 1989 Signal transmission by the insulin-like growth factors. Cell 59:235-238
-
(1989)
Cell
, vol.59
, pp. 235-238
-
-
Czech, M.P.1
-
2
-
-
0023188325
-
After insulin binds
-
Rosen OM 1987 After insulin binds. Science 237:1452-1458
-
(1987)
Science
, vol.237
, pp. 1452-1458
-
-
Rosen, O.M.1
-
3
-
-
0024062933
-
Insulin degradation: Mechanisms, products, and significance
-
Duckworth WC 1988 Insulin degradation: mechanisms, products, and significance. Endocr Rev 9:319-345
-
(1988)
Endocr Rev
, vol.9
, pp. 319-345
-
-
Duckworth, W.C.1
-
4
-
-
0022466733
-
Retroendocytosis of insulin in rat adipocytes
-
Levy JR, Olefsky JM 1986 Retroendocytosis of insulin in rat adipocytes. Endocrinology 119:572-579
-
(1986)
Endocrinology
, vol.119
, pp. 572-579
-
-
Levy, J.R.1
Olefsky, J.M.2
-
5
-
-
0027471458
-
Mutations in a zinc-binding domain of human insulin-degrading enzyme eliminate catalytic activity but not insulin binding
-
Gehm BD, Kuo W-L, Perlman RK, Rosner MR 1993 Mutations in a zinc-binding domain of human insulin-degrading enzyme eliminate catalytic activity but not insulin binding. J Biol Chem 268:7943-7948
-
(1993)
J Biol Chem
, vol.268
, pp. 7943-7948
-
-
Gehm, B.D.1
Kuo, W.-L.2
Perlman, R.K.3
Rosner, M.R.4
-
6
-
-
0023924128
-
Isolation of insulin degradation products from endosomes derived from intact rat liver
-
Hamel FG, Posner BI, Bergeron JJM, Frank BH, Duckworth WC 1988 Isolation of insulin degradation products from endosomes derived from intact rat liver. J Biol Chem 263:6703-6708
-
(1988)
J Biol Chem
, vol.263
, pp. 6703-6708
-
-
Hamel, F.G.1
Posner, B.I.2
Bergeron, J.J.M.3
Frank, B.H.4
Duckworth, W.C.5
-
7
-
-
0023906369
-
Degradation products of insulin generated by hepatocytes and insulin protease
-
Duckworth WC, Hamel FG, Peavey DE, Liepnieks JJ, Ryan MP, Hermodson MA, Frank BH 1988 Degradation products of insulin generated by hepatocytes and insulin protease. J Biol Chem 263:1826-1833
-
(1988)
J Biol Chem
, vol.263
, pp. 1826-1833
-
-
Duckworth, W.C.1
Hamel, F.G.2
Peavey, D.E.3
Liepnieks, J.J.4
Ryan, M.P.5
Hermodson, M.A.6
Frank, B.H.7
-
8
-
-
0024335103
-
Metalloprotease inhibitors which block the differentiation of L6 myoblasts inhibit insulin degradation by the endogenous insulin-degrading enzyme
-
Kayalar C, Wong WT 1989 Metalloprotease inhibitors which block the differentiation of L6 myoblasts inhibit insulin degradation by the endogenous insulin-degrading enzyme. J Biol Chem 264:8928-8934
-
(1989)
J Biol Chem
, vol.264
, pp. 8928-8934
-
-
Kayalar, C.1
Wong, W.T.2
-
9
-
-
0025198488
-
Differentiation of BC3H1 and primary skeletal muscle cells and the activity of their endogenous insulin-degrading enzyme are inhibited by the same metalloendoprotease inhibitors
-
Kayalar C, Wong WT, Hendrickson L 1990 Differentiation of BC3H1 and primary skeletal muscle cells and the activity of their endogenous insulin-degrading enzyme are inhibited by the same metalloendoprotease inhibitors. J Cell Biochem 44:137-151
-
(1990)
J Cell Biochem
, vol.44
, pp. 137-151
-
-
Kayalar, C.1
Wong, W.T.2
Hendrickson, L.3
-
10
-
-
0025809406
-
Regulation of insulin, epidermal growth factor and transforming growth factor alpha levels by growth factor degrading enzymes
-
Gehm BD, Rosner MR 1991 Regulation of insulin, epidermal growth factor and transforming growth factor alpha levels by growth factor degrading enzymes. Endocrinology 128:1603-1610
-
(1991)
Endocrinology
, vol.128
, pp. 1603-1610
-
-
Gehm, B.D.1
Rosner, M.R.2
-
11
-
-
0022445076
-
Inhibition of insulin degradation by hepatoma cells after microinjection of monoclonal antibodies to a specific cytosolic protease
-
Shii K, Roth RA 1986 Inhibition of insulin degradation by hepatoma cells after microinjection of monoclonal antibodies to a specific cytosolic protease. Proc Natl Acad Sci USA 83:4174-4151
-
(1986)
Proc Natl Acad Sci USA
, vol.83
, pp. 4174-14151
-
-
Shii, K.1
Roth, R.A.2
-
12
-
-
0023164755
-
125I]-insulin with a cytosolic insulin-degrading enzyme: Detection by covalent cross-linking and immunoprecipitation with a monoclonal antibody
-
125I]-insulin with a cytosolic insulin-degrading enzyme: detection by covalent cross-linking and immunoprecipitation with a monoclonal antibody. Endocrinology 120:829-831
-
(1987)
Endocrinology
, vol.120
, pp. 829-831
-
-
Hari, J.1
Shii, K.2
Roth, R.A.3
-
13
-
-
0026049145
-
Regulation of insulin degradation: Expression of an evolutionarily conserved insulin-degrading enzyme increases degradation by an intracellular pathway
-
Kuo W-L, Gehm BD, Rosner MR 1991 Regulation of insulin degradation: expression of an evolutionarily conserved insulin-degrading enzyme increases degradation by an intracellular pathway. Mol Endocrinol 5:1467-1476
-
(1991)
Mol Endocrinol
, vol.5
, pp. 1467-1476
-
-
Kuo, W.-L.1
Gehm, B.D.2
Rosner, M.R.3
-
14
-
-
0026661263
-
Processing and presentation of insulin. III. Insulin degrading enzyme: A neutral metalloendoproteinase that is non-homologous to classical endoproteinases mediates the processing of insulin epitopes for helper T cells
-
Semple JW, Lang Y, Speck ER, Delovitch TL1992 Processing and presentation of insulin. III. Insulin degrading enzyme: a neutral metalloendoproteinase that is non-homologous to classical endoproteinases mediates the processing of insulin epitopes for helper T cells. Int Immunol 4:1161-1167
-
(1992)
Int Immunol
, vol.4
, pp. 1161-1167
-
-
Semple, J.W.1
Lang, Y.2
Speck, E.R.3
Delovitch, T.L.4
-
15
-
-
0021195660
-
Degradation of insulin-like growth factors I and II by a human insulin-degrading enzyme
-
Roth RA, Mesirow ML, Yokono K, Baba S 1984 Degradation of insulin-like growth factors I and II by a human insulin-degrading enzyme. Endocr Res 10:101-112
-
(1984)
Endocr Res
, vol.10
, pp. 101-112
-
-
Roth, R.A.1
Mesirow, M.L.2
Yokono, K.3
Baba, S.4
-
16
-
-
0024454036
-
An evolutionarily conserved enzyme degrades transforming growth factor-alpha as well as insulin
-
Garcia JV, Gehm BD, Rosner MR 1989 An evolutionarily conserved enzyme degrades transforming growth factor-alpha as well as insulin. J Cell Biol 109:1301-1307
-
(1989)
J Cell Biol
, vol.109
, pp. 1301-1307
-
-
Garcia, J.V.1
Gehm, B.D.2
Rosner, M.R.3
-
17
-
-
0026471959
-
Rat insulin-degrading enzyme: Cleavage pattern of the natriuretic peptide hormones ANP, BNP, and CNP revealed by HPLC and mass spectrometry
-
Müller D, Schulze C, Baumeister H, Buck F, Richter D 1992 Rat insulin-degrading enzyme: cleavage pattern of the natriuretic peptide hormones ANP, BNP, and CNP revealed by HPLC and mass spectrometry. Biochemistry 31:11138-11143
-
(1992)
Biochemistry
, vol.31
, pp. 11138-11143
-
-
Müller, D.1
Schulze, C.2
Baumeister, H.3
Buck, F.4
Richter, D.5
-
18
-
-
0025916307
-
Purification of a protease in red blood cells that degrades oxidatively damaged haemoglobin
-
Fagan JM, Waxman L 1991 Purification of a protease in red blood cells that degrades oxidatively damaged haemoglobin. Biochem J 277:779-786
-
(1991)
Biochem J
, vol.277
, pp. 779-786
-
-
Fagan, J.M.1
Waxman, L.2
-
19
-
-
0023046298
-
Complete nucleotide sequence of the E. coli ptr gene encoding protease III
-
Finch PW, Wilson RE, Brown K, Hickson ID, Emmerson PT 1986 Complete nucleotide sequence of the E. coli ptr gene encoding protease III. Nucleic Acids Res 14:7695-7703
-
(1986)
Nucleic Acids Res
, vol.14
, pp. 7695-7703
-
-
Finch, P.W.1
Wilson, R.E.2
Brown, K.3
Hickson, I.D.4
Emmerson, P.T.5
-
20
-
-
0024215473
-
Human insulin-degrading enzyme shares structural and functional homology with E. coli protease III
-
Affholter JA, Fried VA, Roth RA 1988 Human insulin-degrading enzyme shares structural and functional homology with E. coli protease III. Science 242:1415-1418
-
(1988)
Science
, vol.242
, pp. 1415-1418
-
-
Affholter, J.A.1
Fried, V.A.2
Roth, R.A.3
-
21
-
-
0025080986
-
Cloning and expression of the cDNA for a Drosophila insulin degrading enzyme
-
Kuo W-L, Gehm BD, Rosner MR 1991 Cloning and expression of the cDNA for a Drosophila insulin degrading enzyme. Mol Endocrinol 4:1580-1591
-
(1991)
Mol Endocrinol
, vol.4
, pp. 1580-1591
-
-
Kuo, W.-L.1
Gehm, B.D.2
Rosner, M.R.3
-
22
-
-
0027410472
-
The rat insulin-degrading enzyme: Molecular cloning and characterization of tissue-specific transcripts
-
Baumeister H, Müller D, Rehbein M, Richtet D 1993 The rat insulin-degrading enzyme: molecular cloning and characterization of tissue-specific transcripts. FEBS Lett 317:250-254
-
(1993)
FEBS Lett
, vol.317
, pp. 250-254
-
-
Baumeister, H.1
Müller, D.2
Rehbein, M.3
Richtet, D.4
-
23
-
-
0028879135
-
Role of yeast insulin-degrading enzyme homologs in propheromone processing and bud site selection
-
Adames N, Blundell K, Ashby MN, Boone C 1995 Role of yeast insulin-degrading enzyme homologs in propheromone processing and bud site selection. Science 270:464-467
-
(1995)
Science
, vol.270
, pp. 464-467
-
-
Adames, N.1
Blundell, K.2
Ashby, M.N.3
Boone, C.4
-
24
-
-
0027454093
-
Functional analysis of conserved residues in the active site of the insulin degrading enzyme
-
Perlman RK, Gehm BD, Kuo W-L, Rosner MR 1993 Functional analysis of conserved residues in the active site of the insulin degrading enzyme. J Biol Chem 268:21538-21544
-
(1993)
J Biol Chem
, vol.268
, pp. 21538-21544
-
-
Perlman, R.K.1
Gehm, B.D.2
Kuo, W.-L.3
Rosner, M.R.4
-
25
-
-
0024521811
-
A conserved tripeptide sorts proteins to peroxisomes
-
Gould SJ, Keller G-A, Hosken N, Wilkinson J, Subramani S 1989 A conserved tripeptide sorts proteins to peroxisomes. J Cell Biol 108:1657-1664
-
(1989)
J Cell Biol
, vol.108
, pp. 1657-1664
-
-
Gould, S.J.1
Keller, G.-A.2
Hosken, N.3
Wilkinson, J.4
Subramani, S.5
-
26
-
-
0026643496
-
Carboxyl-terminal consensus Ser-Lys-Leu-related tripeptide of peroxisomal proteins functions in vitro as a minimal peroxisome-targeting signal
-
Miura S, Kasuya-Arai I, Mori H, Miyazawa S, Osumi T, Hashimoto T, Fujiki Y 1992 Carboxyl-terminal consensus Ser-Lys-Leu-related tripeptide of peroxisomal proteins functions in vitro as a minimal peroxisome-targeting signal. J Biol Chem 267:14405-14411
-
(1992)
J Biol Chem
, vol.267
, pp. 14405-14411
-
-
Miura, S.1
Kasuya-Arai, I.2
Mori, H.3
Miyazawa, S.4
Osumi, T.5
Hashimoto, T.6
Fujiki, Y.7
-
27
-
-
0027333416
-
Protein import into peroxisomes and biogenesis of the organelle
-
Subramani S 1993 Protein import into peroxisomes and biogenesis of the organelle. Annu Rev Cell Biol 9:445-478
-
(1993)
Annu Rev Cell Biol
, vol.9
, pp. 445-478
-
-
Subramani, S.1
-
29
-
-
0025941962
-
A novel, cleavable peroxisomal targeting signal at the amino-terminus of the rat 3-ketoacyl-CoA thiolase
-
Swinkels BW, Gould SJ, Bodnar AG, Rachubinski RA, Subramani S 1991 A novel, cleavable peroxisomal targeting signal at the amino-terminus of the rat 3-ketoacyl-CoA thiolase. EMBO J 10:3255-3262
-
(1991)
EMBO J
, vol.10
, pp. 3255-3262
-
-
Swinkels, B.W.1
Gould, S.J.2
Bodnar, A.G.3
Rachubinski, R.A.4
Subramani, S.5
-
30
-
-
0028040778
-
Endosomal proteolysis of insulin by an acidic thiol metalloprotease unrelated to insulin degrading enzyme
-
Authier F, Rachubinski RA, Posner BI, Bergeron M 1994 Endosomal proteolysis of insulin by an acidic thiol metalloprotease unrelated to insulin degrading enzyme. J Biol Chem 269:3010-3016
-
(1994)
J Biol Chem
, vol.269
, pp. 3010-3016
-
-
Authier, F.1
Rachubinski, R.A.2
Posner, B.I.3
Bergeron, M.4
-
31
-
-
0027964969
-
Inducible expression and cellular localization of insulin-degrading enzyme in a stably transfected cell line
-
Kuo W-L, Gehm BD, Rosner MR, Li W, Keller G 1994 Inducible expression and cellular localization of insulin-degrading enzyme in a stably transfected cell line. J Biol Chem 269:22599-22606
-
(1994)
J Biol Chem
, vol.269
, pp. 22599-22606
-
-
Kuo, W.-L.1
Gehm, B.D.2
Rosner, M.R.3
Li, W.4
Keller, G.5
-
32
-
-
0029024878
-
Degradation of the cleaved leader peptide of thiolase by a peroxisomal proteinase
-
Authier F, Bergeron JJM, Ou W-J, Rachubinski RA, Posner BI, Walton PA 1995 Degradation of the cleaved leader peptide of thiolase by a peroxisomal proteinase. Proc Natl Acad Sci USA 92:3859-3863
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 3859-3863
-
-
Authier, F.1
Bergeron, J.J.M.2
Ou, W.-J.3
Rachubinski, R.A.4
Posner, B.I.5
Walton, P.A.6
-
33
-
-
0027452730
-
Insulin degrading enzyme is differentially expressed and developmentally regulated in various rat tissues
-
Kuo W-L, Montag AG, Rosner MR 1993 Insulin degrading enzyme is differentially expressed and developmentally regulated in various rat tissues. Endocrinology 132:604-611
-
(1993)
Endocrinology
, vol.132
, pp. 604-611
-
-
Kuo, W.-L.1
Montag, A.G.2
Rosner, M.R.3
-
34
-
-
0017184389
-
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
-
Bradford MM 1976 A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72:248-254
-
(1976)
Anal Biochem
, vol.72
, pp. 248-254
-
-
Bradford, M.M.1
-
35
-
-
0014949207
-
Cleavage of structural proteins during the assembly of the head of bacteriophage T4
-
Laemmli UK 1970 Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227:680-685
-
(1970)
Nature
, vol.227
, pp. 680-685
-
-
Laemmli, U.K.1
-
36
-
-
0028587344
-
Identification of zinc ligands of the insulin-degrading enzyme
-
Perlman RK, Rosner MR 1994 Identification of zinc ligands of the insulin-degrading enzyme. J Biol Chem 269:33140-33145
-
(1994)
J Biol Chem
, vol.269
, pp. 33140-33145
-
-
Perlman, R.K.1
Rosner, M.R.2
-
37
-
-
0026601458
-
Site-directed mutagenesis of virtually any plasmid by eliminating a unique site
-
Deng WP, Nickoloff JA 1992 Site-directed mutagenesis of virtually any plasmid by eliminating a unique site. Anal Biochem 200:81-88
-
(1992)
Anal Biochem
, vol.200
, pp. 81-88
-
-
Deng, W.P.1
Nickoloff, J.A.2
-
40
-
-
0025255475
-
The 70-kDa peroxisomal membrane protein is a member of the Mdr (P-glvcoprotein)-related ATP-binding protein superfamily
-
Kamijo K, Taketani S, Yokota S, Osumi T, Hashimoto T 1990 The 70-kDa peroxisomal membrane protein is a member of the Mdr (P-glvcoprotein)-related ATP-binding protein superfamily. J Biol Chem 265:4534-4540
-
(1990)
J Biol Chem
, vol.265
, pp. 4534-4540
-
-
Kamijo, K.1
Taketani, S.2
Yokota, S.3
Osumi, T.4
Hashimoto, T.5
-
41
-
-
0024076281
-
Identification of peroxisomal targeting signals located at the carboxy terminus of four peroxisomal proteins
-
Gould SJ, Keller G-A, Subramani S 1988 Identification of peroxisomal targeting signals located at the carboxy terminus of four peroxisomal proteins. J Cell Biol 107:897-905
-
(1988)
J Cell Biol
, vol.107
, pp. 897-905
-
-
Gould, S.J.1
Keller, G.-A.2
Subramani, S.3
-
42
-
-
0026027138
-
Assembly of alcohol oxidase in the cytosol of a peroxisome-deficient mutant of Hansenula polymorpha - Properties of the protein and architecture of the crystals
-
Van der Klei IJ, Suiter GJ, Harder W, Veenhuis M 1991 Assembly of alcohol oxidase in the cytosol of a peroxisome-deficient mutant of Hansenula polymorpha - properties of the protein and architecture of the crystals. Yeast 7:15-24
-
(1991)
Yeast
, vol.7
, pp. 15-24
-
-
Van Der Klei, I.J.1
Suiter, G.J.2
Harder, W.3
Veenhuis, M.4
-
43
-
-
0027168271
-
The pas8 mutant of Pichia pastoris exhibits the peroxisomal protein import deficiencies of Zellweger syndrome cells - The PAS8 protein binds to the COOH-terminal tripeptide peroxisomal targeting signal, and is a member of the TPR protein family
-
McCollum D, Monosov E, Subramani S 1993 The pas8 mutant of Pichia pastoris exhibits the peroxisomal protein import deficiencies of Zellweger syndrome cells - the PAS8 protein binds to the COOH-terminal tripeptide peroxisomal targeting signal, and is a member of the TPR protein family. J Cell Biol 121:761-774
-
(1993)
J Cell Biol
, vol.121
, pp. 761-774
-
-
McCollum, D.1
Monosov, E.2
Subramani, S.3
-
45
-
-
0029811040
-
Association of insulin-degrading enzyme with a 70 kDa cytosolic protein in hepatoma cells
-
Authier F, Cameron PH, Taupin V 1996 Association of insulin-degrading enzyme with a 70 kDa cytosolic protein in hepatoma cells. Biochem J 319:149-158
-
(1996)
Biochem J
, vol.319
, pp. 149-158
-
-
Authier, F.1
Cameron, P.H.2
Taupin, V.3
-
46
-
-
0029869726
-
Cytoplasmic and peroxisomal catalases of the guinea pig liver: Evidence for two distinct proteins
-
Bulitta C, Ganea C, Fahimi HD, Völkl A 1996 Cytoplasmic and peroxisomal catalases of the guinea pig liver: evidence for two distinct proteins. Biochim Biophys Acta 1293:55-62
-
(1996)
Biochim Biophys Acta
, vol.1293
, pp. 55-62
-
-
Bulitta, C.1
Ganea, C.2
Fahimi, H.D.3
Völkl, A.4
-
47
-
-
0026722418
-
Direct stimulation of immediate-early genes by intranuclear insulin in trypsin-treated H35 hepatoma cells
-
Lin YJ, Harada S, Loten EG, Smith RM, Jarett L 1992 Direct stimulation of immediate-early genes by intranuclear insulin in trypsin-treated H35 hepatoma cells. Proc Natl Acad Sci USA 89:9691-9694
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 9691-9694
-
-
Lin, Y.J.1
Harada, S.2
Loten, E.G.3
Smith, R.M.4
Jarett, L.5
-
48
-
-
0027157869
-
Inhibition of insulin-degrading enzyme increases translocation of insulin to the nucleus in H35 rat hepatoma cells: Evidence of a cytosolic pathway
-
Harada S, Smith RM, Smith J-A, Jarret L 1993 Inhibition of insulin-degrading enzyme increases translocation of insulin to the nucleus in H35 rat hepatoma cells: evidence of a cytosolic pathway. Endocrinology 132:2293-2298
-
(1993)
Endocrinology
, vol.132
, pp. 2293-2298
-
-
Harada, S.1
Smith, R.M.2
Smith, J.-A.3
Jarret, L.4
-
49
-
-
0029043047
-
Electron microscopic visualization of insulin translocation into the cytoplasm and nuclei of intact H35 hepatoma cells using covalently linked nanogold-insulin
-
Shah N, Zhang S, Harada S, Smith SM, Jarett L 1995 Electron microscopic visualization of insulin translocation into the cytoplasm and nuclei of intact H35 hepatoma cells using covalently linked nanogold-insulin. Endocrinology 136:2825-2835
-
(1995)
Endocrinology
, vol.136
, pp. 2825-2835
-
-
Shah, N.1
Zhang, S.2
Harada, S.3
Smith, S.M.4
Jarett, L.5
-
50
-
-
0025991780
-
Multiple pathways for ligand internalization in rat hepatocytes II: Effect of hyperosmolarity and contribution of fluid-phase endocytosis
-
Moss AL, Ward WF 1991 Multiple pathways for ligand internalization in rat hepatocytes II: effect of hyperosmolarity and contribution of fluid-phase endocytosis. J Cell Physiol 149:319-323
-
(1991)
J Cell Physiol
, vol.149
, pp. 319-323
-
-
Moss, A.L.1
Ward, W.F.2
-
51
-
-
0026343342
-
Insulin receptors internalize by a rapid, saturable pathway requiring receptor autophosphorylation and an intact juxtamembrane region
-
Backer JM, Shoelson SE, Haring E, White MF 1991 Insulin receptors internalize by a rapid, saturable pathway requiring receptor autophosphorylation and an intact juxtamembrane region. J Cell Biol 115:1535-1545
-
(1991)
J Cell Biol
, vol.115
, pp. 1535-1545
-
-
Backer, J.M.1
Shoelson, S.E.2
Haring, E.3
White, M.F.4
-
52
-
-
0029066902
-
1 complex evolutionary relics of a processing protease
-
1 complex evolutionary relics of a processing protease. Trends Biochem Sci 20:171-175
-
(1995)
Trends Biochem Sci
, vol.20
, pp. 171-175
-
-
Braun, H.-P.1
Schmitz, U.2
-
53
-
-
0029039898
-
Purification and characterization of mitochondrial processing peptidase of Neurospora crassa
-
Brunner M, Neupert W 1995 Purification and characterization of mitochondrial processing peptidase of Neurospora crassa. Methods Enzymol 248:717-728
-
(1995)
Methods Enzymol
, vol.248
, pp. 717-728
-
-
Brunner, M.1
Neupert, W.2
|