-
1
-
-
0025343230
-
Signal transduction by receptors with tyrosine kinase activity
-
Ullrich A, Schlessinger J (1990) Signal transduction by receptors with tyrosine kinase activity. Cell 61: 203-212
-
(1990)
Cell
, vol.61
, pp. 203-212
-
-
Ullrich, A.1
Schlessinger, J.2
-
3
-
-
0027502045
-
Purified hybrid insulin/insulin-like growth factor-I receptors bind insulin-like growth factor-I, but not insulin, with high affinity
-
Soos MA, Field CE, Siddle K (1993) Purified hybrid insulin/insulin-like growth factor-I receptors bind insulin-like growth factor-I, but not insulin, with high affinity. Biochem J 290: 419-426
-
(1993)
Biochem J
, vol.290
, pp. 419-426
-
-
Soos, M.A.1
Field, C.E.2
Siddle, K.3
-
4
-
-
0023267760
-
Isolation of functional a-b heterodimers from he purified human placental α2-β2 heterotetrameric insulin receptor concept. Structural basis for high affinity ligand binding
-
Sweet LJ, Morrison BD, Pessin J (1987) Isolation of functional a-b heterodimers from (he purified human placental α2-β2 heterotetrameric insulin receptor concept. Structural basis for high affinity ligand binding. J Biol Chem 262: 6939-6942
-
(1987)
J Biol Chem
, vol.262
, pp. 6939-6942
-
-
Sweet, L.J.1
Morrison, B.D.2
Pessin, J.3
-
5
-
-
0023924374
-
Phosphorylation of insulin-like growth factor-I receptor by insulin receptor tyrosine kinase in intact cultured skeletal muscle cells
-
Beguinot F, Smith RJ, Kahn CR, Maron R, Moses AC, White MF (1988) Phosphorylation of insulin-like growth factor-I receptor by insulin receptor tyrosine kinase in intact cultured skeletal muscle cells. Biochemistry 27: 3222-3228
-
(1988)
Biochemistry
, vol.27
, pp. 3222-3228
-
-
Beguinot, F.1
Smith, R.J.2
Kahn, C.R.3
Maron, R.4
Moses, A.C.5
White, M.F.6
-
7
-
-
0028146822
-
The structural basis of insulin and insulin-like growth factor-I (IGF-I) receptor binding and negative co-opcrativity, and its relevance to mitogenic versus metabolic signalling
-
De Meyts P (1994) The structural basis of insulin and insulin-like growth factor-I (IGF-I) receptor binding and negative co-opcrativity, and its relevance to mitogenic versus metabolic signalling. Diabetologia 37[Suppl 2]:S135-S148
-
(1994)
Diabetologia
, vol.37
, Issue.2 SUPPL.
-
-
De Meyts, P.1
-
8
-
-
0027944978
-
The insulin-like growth factor-I receptor. Structure, ligand binding mechanism and signal transduclion
-
De Meyts P, Wallach B, Christoffersen CT et al. (1994) The insulin-like growth factor-I receptor. Structure, ligand binding mechanism and signal transduclion. Horm Res 42: 152-169
-
(1994)
Horm Res
, vol.42
, pp. 152-169
-
-
De Meyts, P.1
Wallach, B.2
Christoffersen, C.T.3
-
9
-
-
0028033666
-
The overexpression of insulin receptor makes CHO cells resistant to the action of IGF-I. Role of IRS-1
-
Maggi D, Laurino C, Andraghetti G, Cordera R (1994) The overexpression of insulin receptor makes CHO cells resistant to the action of IGF-I. Role of IRS-1. Biochem Biophys Res Commun 205: 693-699
-
(1994)
Biochem Biophys Res Commun
, vol.205
, pp. 693-699
-
-
Maggi, D.1
Laurino, C.2
Andraghetti, G.3
Cordera, R.4
-
10
-
-
0023184872
-
Activation of the transforming potential of the human insulin receptor gene
-
Wang LH, Lin B, Jong S-MJ, Dixon D, Ellis L, Roth RA, Rutter WJ (1987) Activation of the transforming potential of the human insulin receptor gene. Proc Natl Acad Sci USA 84: 5725-5729
-
(1987)
Proc Natl Acad Sci USA
, vol.84
, pp. 5725-5729
-
-
Wang, L.H.1
Lin, B.2
Jong, S.-M.J.3
Dixon, D.4
Ellis, L.5
Roth, R.A.6
Rutter, W.J.7
-
11
-
-
0001008384
-
Carcinogenic effect on female rats after 12 months administration of the insulin analogue BlO Asp
-
Abstract
-
Dideriksen LH, Jørgensen LN, Drejer K (1992) Carcinogenic effect on female rats after 12 months administration of the insulin analogue BlO Asp. Diabetes 41 [Suppl 1]:143A (Abstract)
-
(1992)
Diabetes
, vol.41
, Issue.1 SUPPL.
-
-
Dideriksen, L.H.1
Jørgensen, L.N.2
Drejer, K.3
-
12
-
-
0025894102
-
Binding and biological effects of insulin, insulin analogues and insulin-like growth factors in rat aortic smooth muscle cells. Comparison of maximal growth-promoting activities
-
Bornfeldt KE, Gidlöf RA, Wasteson A, Lake M, Skottner A, Arnqvist HJ (1991) Binding and biological effects of insulin, insulin analogues and insulin-like growth factors in rat aortic smooth muscle cells. Comparison of maximal growth-promoting activities. Diabetologia 34: 307-313
-
(1991)
Diabetologia
, vol.34
, pp. 307-313
-
-
Bornfeldt, K.E.1
Gidlöf, R.A.2
Wasteson, A.3
Lake, M.4
Skottner, A.5
Arnqvist, H.J.6
-
13
-
-
0002276918
-
Insulin potency as a mitogen is determined by the half-life of the insulin-receptor complex
-
De Meyts P, Christoffersen CT, Ursø B et al. (1993) Insulin potency as a mitogen is determined by the half-life of the insulin-receptor complex. Exp Clin Endocrinol Leipzig 101: 22-23
-
(1993)
Exp Clin Endocrinol Leipzig
, vol.101
, pp. 22-23
-
-
De Meyts, P.1
Christoffersen, C.T.2
Ursø, B.3
-
14
-
-
0029862845
-
Sustained signalling from the insulin receptor after stimulation with insulin analogues exhibiting increased mitogenic potency
-
Hansen BF, Danielsen GM, Drejer K et al. (1996) Sustained signalling from the insulin receptor after stimulation with insulin analogues exhibiting increased mitogenic potency. Biochem J 315: 271-279
-
(1996)
Biochem J
, vol.315
, pp. 271-279
-
-
Hansen, B.F.1
Danielsen, G.M.2
Drejer, K.3
-
15
-
-
0029970843
-
Nutrition, hormones, and breast cancer: Is insulin the missing link?
-
Kaaks R (1996) Nutrition, hormones, and breast cancer: Is insulin the missing link? Cancer causes and control 7: 605-625
-
(1996)
Cancer Causes and Control
, vol.7
, pp. 605-625
-
-
Kaaks, R.1
-
16
-
-
0019434698
-
Insulin as a potent, specific growth factor in a rat hepatoma cell line
-
Koontz JW, Iwahashi M (1981) Insulin as a potent, specific growth factor in a rat hepatoma cell line. Science 211: 947-949
-
(1981)
Science
, vol.211
, pp. 947-949
-
-
Koontz, J.W.1
Iwahashi, M.2
-
17
-
-
0018343498
-
Insulin receptors and functions in normal and spontaneously transformed cloned rat hepatocytes
-
Petersen B, Blecher M (1979) Insulin receptors and functions in normal and spontaneously transformed cloned rat hepatocytes. Exp Cell Res 120: 119-125
-
(1979)
Exp Cell Res
, vol.120
, pp. 119-125
-
-
Petersen, B.1
Blecher, M.2
-
18
-
-
0019250910
-
Cultured hepatoma cells as a model system for studying insulin processing and biologic responsiveness
-
Hofmann C, Marsh JW, Miller B, Steiner DF (1980) Cultured hepatoma cells as a model system for studying insulin processing and biologic responsiveness. Diabetes 29: 865-874
-
(1980)
Diabetes
, vol.29
, pp. 865-874
-
-
Hofmann, C.1
Marsh, J.W.2
Miller, B.3
Steiner, D.F.4
-
19
-
-
0020378220
-
Insulin promotes the growth of F9 embryonal cells apparently by acting through its own receptor
-
Nagarajan L, Anderson WB (1982) Insulin promotes the growth of F9 embryonal cells apparently by acting through its own receptor. Biochem Biophys Res Commun 106: 974-980
-
(1982)
Biochem Biophys Res Commun
, vol.106
, pp. 974-980
-
-
Nagarajan, L.1
Anderson, W.B.2
-
20
-
-
0027303072
-
Insulin and IGF-I increase mitogenesis and glucose metabolism in the multiple myeloma cell line, RPMI-8226
-
Freund GG, Kulas DT, Mooney RA (1993) Insulin and IGF-I increase mitogenesis and glucose metabolism in the multiple myeloma cell line, RPMI-8226. J lmmunol 151: 1811-1820
-
(1993)
J Lmmunol
, vol.151
, pp. 1811-1820
-
-
Freund, G.G.1
Kulas, D.T.2
Mooney, R.A.3
-
21
-
-
0024351132
-
The insulin receptor as a transmitter of a mitogenic signal in Chinese hamster ovary CHO-K1 cells
-
Mamounas M, Gervin D, Englesberg E (1989) The insulin receptor as a transmitter of a mitogenic signal in Chinese hamster ovary CHO-K1 cells. Proc Natl Acad Sci U.S.A. 86: 9294-9298
-
(1989)
Proc Natl Acad Sci U.S.A.
, vol.86
, pp. 9294-9298
-
-
Mamounas, M.1
Gervin, D.2
Englesberg, E.3
-
22
-
-
0025782888
-
Analysis of the genes involved in the transmembrane mitogenic signal in Chinese hamster ovary cells, CHO-K1, utilizing insulin-independent mutants
-
Mamounas M, Ross S, Luong CL et al. (1991) Analysis of the genes involved in the transmembrane mitogenic signal in Chinese hamster ovary cells, CHO-K1, utilizing insulin-independent mutants. Proc Natl Acad Sci USA 88: 3524-3530
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, pp. 3524-3530
-
-
Mamounas, M.1
Ross, S.2
Luong, C.L.3
-
23
-
-
0024358801
-
Differential signalling potential of insulin- and IGF-I-receptor cytoplasmic domains
-
Lammers R, Gray A, Schlessinger J, Ullrich A (1989) Differential signalling potential of insulin- and IGF-I-receptor cytoplasmic domains. EMBO J 8: 1369-1375
-
(1989)
EMBO J
, vol.8
, pp. 1369-1375
-
-
Lammers, R.1
Gray, A.2
Schlessinger, J.3
Ullrich, A.4
-
24
-
-
0029550646
-
Mitogenic potential of insulin on lymphoma cells lacking IGF-I receptors
-
Ish-Shalom D, Tzivion G, Christoffersen CT, Ursø B, De Meyts P Naor D (1995) Mitogenic potential of insulin on lymphoma cells lacking IGF-I receptors. Ann N Y Acad Sci 766: 409-415
-
(1995)
Ann N Y Acad Sci
, vol.766
, pp. 409-415
-
-
Ish-Shalom, D.1
Tzivion, G.2
Christoffersen, C.T.3
Ursø, B.4
De Meyts, P.5
Naor, D.6
-
25
-
-
0029032423
-
Lymph node (but not spleen) invasion by murine lymphoma is both CD44- and hyaluronate dependent
-
Zahalka AM, Okon E, Gosslar U, Holzmann B, Naor D (1995) Lymph node (but not spleen) invasion by murine lymphoma is both CD44- and hyaluronate dependent. J Immunol 154: 5345-5355
-
(1995)
J Immunol
, vol.154
, pp. 5345-5355
-
-
Zahalka, A.M.1
Okon, E.2
Gosslar, U.3
Holzmann, B.4
Naor, D.5
-
26
-
-
0021955971
-
"Concomitant immunity" in murine tumours of non-detectable immunogenicity
-
Ruggiero RA, Bustuoabad OD, Bonfil RD, Meiss RP, Pasqualini CD (1985) "Concomitant immunity" in murine tumours of non-detectable immunogenicity. Brit J Cancer 51: 37-48
-
(1985)
Brit J Cancer
, vol.51
, pp. 37-48
-
-
Ruggiero, R.A.1
Bustuoabad, O.D.2
Bonfil, R.D.3
Meiss, R.P.4
Pasqualini, C.D.5
-
27
-
-
0022590502
-
Histologie aspects of concomitant resistance induced by non-immunogenic murine tumours
-
Meiss RP, Bonfil RD, Ruggiero RA, Pasqualini CD (1986) Histologie aspects of concomitant resistance induced by non-immunogenic murine tumours. J Natl Cancer Inst 76: 1163-1175
-
(1986)
J Natl Cancer Inst
, vol.76
, pp. 1163-1175
-
-
Meiss, R.P.1
Bonfil, R.D.2
Ruggiero, R.A.3
Pasqualini, C.D.4
-
29
-
-
0027523609
-
Insulin dependence of murine T-cell lymphoma. 2. Insulin-deficient mice and mice fed low-energy diet develop resistance to lymphoma growth
-
Sharon R, Pillemer G, Ish-Shalom D et al. (1993) Insulin dependence of murine T-cell lymphoma. 2. Insulin-deficient mice and mice fed low-energy diet develop resistance to lymphoma growth. Int J Cancer 53: 843-849
-
(1993)
Int J Cancer
, vol.53
, pp. 843-849
-
-
Sharon, R.1
Pillemer, G.2
Ish-Shalom, D.3
-
30
-
-
0028235085
-
Negative co-operativity in the insulin-like growth factor-I (IGF-I) receptor and a chimeric IGF-I/insulin receptor
-
Christoffersen CT, Bornfeldt KE, Rotella CM et al. (1994) Negative co-operativity in the insulin-like growth factor-I (IGF-I) receptor and a chimeric IGF-I/insulin receptor. Endocrinology 135: 472-475
-
(1994)
Endocrinology
, vol.135
, pp. 472-475
-
-
Christoffersen, C.T.1
Bornfeldt, K.E.2
Rotella, C.M.3
-
31
-
-
0002506909
-
Insulin and growth hormone receptors in human cultured lymphocytes and peripheral blood monocytes
-
Blecher M (ed) Marcel Dekker, New York
-
De Meyts P (1976) Insulin and growth hormone receptors in human cultured lymphocytes and peripheral blood monocytes. In: Blecher M (ed) Methods in receptor research. Marcel Dekker, New York, pp 301-383
-
(1976)
Methods in Receptor Research
, pp. 301-383
-
-
De Meyts, P.1
-
32
-
-
0017224874
-
Site-site interactions among insulin receptors: Characterization of the negative co-operativity
-
De Meyts P, Bianco AR, Roth J (1976) Site-site interactions among insulin receptors: characterization of the negative co-operativity. J Biol Chem 251: 1877-1888
-
(1976)
J Biol Chem
, vol.251
, pp. 1877-1888
-
-
De Meyts, P.1
Bianco, A.R.2
Roth, J.3
-
33
-
-
0018102801
-
Mapping of the residues of the receptor binding region of insulin responsible for the negative cooperativity
-
De Meyts P, Van Obberghen E, Roth J, Brandenburg D, Wollmer A (1978) Mapping of the residues of the receptor binding region of insulin responsible for the negative cooperativity. Nature 273: 504-509
-
(1978)
Nature
, vol.273
, pp. 504-509
-
-
De Meyts, P.1
Van Obberghen, E.2
Roth, J.3
Brandenburg, D.4
Wollmer, A.5
-
34
-
-
0025078913
-
Monomeric insulins and their experimental and clinical implications
-
Brange J, Owens D, Kang S, Vølund A (1990) Monomeric insulins and their experimental and clinical implications. Diabetes Care 13: 923-954
-
(1990)
Diabetes Care
, vol.13
, pp. 923-954
-
-
Brange, J.1
Owens, D.2
Kang, S.3
Vølund, A.4
-
35
-
-
0027097641
-
The bioactivity of insulin analogues from in vitro receptor binding to in vivo glucose uptake
-
Drejer K (1992) The bioactivity of insulin analogues from in vitro receptor binding to in vivo glucose uptake. Diabetes Metab Rev 8: 259-286
-
(1992)
Diabetes Metab Rev
, vol.8
, pp. 259-286
-
-
Drejer, K.1
-
36
-
-
0024845664
-
Substrate phosphorylation catalyzed by the insulin receptor tyrosine kinase. Kinetic correlation to autophosphorylation of specific sites in the beta subunit
-
Flores-Riveros JR, Sibley E, Kastelic C, Lane MD (1989) Substrate phosphorylation catalyzed by the insulin receptor tyrosine kinase. Kinetic correlation to autophosphorylation of specific sites in the beta subunit. J Biol Chem 264: 21557-21572
-
(1989)
J Biol Chem
, vol.264
, pp. 21557-21572
-
-
Flores-Riveros, J.R.1
Sibley, E.2
Kastelic, C.3
Lane, M.D.4
-
37
-
-
0026761432
-
Mutations in the insulin receptor gene
-
Taylor S, Cama A, Accili D et al. (1992) Mutations in the insulin receptor gene. Endocrine Rev 13: 566-595
-
(1992)
Endocrine Rev
, vol.13
, pp. 566-595
-
-
Taylor, S.1
Cama, A.2
Accili, D.3
-
38
-
-
0022643442
-
Characterization of insulin, insulin-like growth factors I and II, and growth hormone receptors on human leukemic lymphoblasts
-
Lee PD, Rosenfeld RG, Hintz RL, Smith SD (1986) Characterization of insulin, insulin-like growth factors I and II, and growth hormone receptors on human leukemic lymphoblasts. J Clin Endo Metab 62: 28-35
-
(1986)
J Clin Endo Metab
, vol.62
, pp. 28-35
-
-
Lee, P.D.1
Rosenfeld, R.G.2
Hintz, R.L.3
Smith, S.D.4
-
39
-
-
0019947098
-
Inducible expression of insulin receptors on T lymphocyte clones
-
Braciale VL, Gavin JRI, Braciale TJ (1982) Inducible expression of insulin receptors on T lymphocyte clones. J Exp Med 156: 664-669
-
(1982)
J Exp Med
, vol.156
, pp. 664-669
-
-
Braciale, V.L.1
Gavin, J.R.I.2
Braciale, T.J.3
-
41
-
-
0029391379
-
Role of the time factor in signalling specificity. Application to mitogenic and metabolic signalling by the insulin and insulin-like growth factor-I receptor tyrosine kinases
-
De Meyts P, Christoffersen CT, Ursø B et al. (1995) Role of the time factor in signalling specificity. Application to mitogenic and metabolic signalling by the insulin and insulin-like growth factor-I receptor tyrosine kinases. Metabolism 44[Suppl4]:1-11
-
(1995)
Metabolism
, vol.44
, Issue.4 SUPPL.
, pp. 1-11
-
-
De Meyts, P.1
Christoffersen, C.T.2
Ursø, B.3
-
42
-
-
0029550774
-
Mechanism of insulin and IGF-I receptor activation and signal transduction specificity. Receptor dimer crosslinking, bell-shaped curves, and sustained versus transient signalling
-
De Meyts P, Ursø B, Christoffersen CT, Shymko RM (1995) Mechanism of insulin and IGF-I receptor activation and signal transduction specificity. Receptor dimer crosslinking, bell-shaped curves, and sustained versus transient signalling. Ann New York Acad Sci 766: 388-401
-
(1995)
Ann New York Acad Sci
, vol.766
, pp. 388-401
-
-
De Meyts, P.1
Ursø, B.2
Christoffersen, C.T.3
Shymko, R.M.4
-
43
-
-
0001314221
-
The hemoglobin system. VI. The oxygen dissociation curve of hemoglobin
-
Adair GS (1925) The hemoglobin system. VI. The oxygen dissociation curve of hemoglobin. J Biol Chem 63: 529-545
-
(1925)
J Biol Chem
, vol.63
, pp. 529-545
-
-
Adair, G.S.1
-
44
-
-
0001758651
-
Developmental regulation of the rat insulin-like growth factor-I receptor gene
-
Werner H, Woloschak M, Adamo M, Shen-Orr Z, Roberts CT Jr, LeRoith D (1989) Developmental regulation of the rat insulin-like growth factor-I receptor gene. Proc Natl Acad Sci 86: 7451-7455
-
(1989)
Proc Natl Acad Sci
, vol.86
, pp. 7451-7455
-
-
Werner, H.1
Woloschak, M.2
Adamo, M.3
Shen-Orr, Z.4
Roberts Jr., C.T.5
LeRoith, D.6
-
45
-
-
8544236387
-
Membrane linked insulin receptor tyrosine kinase stimulates the insulin specific response
-
Goren HJ, Hollenberg MD, Roncari DAK (eds) Raven Press. New York
-
Rutter WJ, Morgan D, Ebina Y, Wang LH, Roth R, Ellis L (1988) Membrane linked insulin receptor tyrosine kinase stimulates the insulin specific response. In: Goren HJ, Hollenberg MD, Roncari DAK (eds) Insulin action and diabetes. Raven Press. New York, pp 1-12
-
(1988)
Insulin Action and Diabetes
, pp. 1-12
-
-
Rutter, W.J.1
Morgan, D.2
Ebina, Y.3
Wang, L.H.4
Roth, R.5
Ellis, L.6
|