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Volumn 7, Issue 1, 1997, Pages 7-16

Phosphorylation and proteolysis: Partners in the regulation of cell division in budding yeast

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN B; CYCLIN DEPENDENT KINASE; UBIQUITIN;

EID: 0031056127     PISSN: 0959437X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0959-437X(97)80103-7     Document Type: Article
Times cited : (84)

References (80)
  • 1
    • 0028292454 scopus 로고
    • Cell cycle regulated transcription in yeast
    • Koch C, Nasmyth K. Cell cycle regulated transcription in yeast. Curr Opin Cell Biol. 6:1994;451-459.
    • (1994) Curr Opin Cell Biol , vol.6 , pp. 451-459
    • Koch, C.1    Nasmyth, K.2
  • 2
    • 0028876046 scopus 로고
    • Starting the cell cycle: What's the point
    • Cross FR. Starting the cell cycle: what's the point. Curr Opin Cell Biol. 7:1994;790-797.
    • (1994) Curr Opin Cell Biol , vol.7 , pp. 790-797
    • Cross, F.R.1
  • 3
    • 0028828193 scopus 로고
    • The self-destructive personality of a cell cycle in transition
    • Deshaies RJ. The self-destructive personality of a cell cycle in transition. Curr Opin Cell Biol. 7:1995;781-789.
    • (1995) Curr Opin Cell Biol , vol.7 , pp. 781-789
    • Deshaies, R.J.1
  • 4
    • 0028935165 scopus 로고
    • Ubiquitin, proteasomes, and the regulation of intracellular protein degradation
    • Hochstrasser M. Ubiquitin, proteasomes, and the regulation of intracellular protein degradation. Curr Opin Cell Biol. 7:1995;215-223.
    • (1995) Curr Opin Cell Biol , vol.7 , pp. 215-223
    • Hochstrasser, M.1
  • 5
    • 0030598895 scopus 로고    scopus 로고
    • A deubiquitinating enzyme interacts with SIR4 and regulates silencing in S. cerevisiae
    • Moazed D, Johnson AD. A deubiquitinating enzyme interacts with SIR4 and regulates silencing in S. cerevisiae. Cell. 86:1996;667-677.
    • (1996) Cell , vol.86 , pp. 667-677
    • Moazed, D.1    Johnson, A.D.2
  • 6
    • 0029761435 scopus 로고    scopus 로고
    • 1 defines a 'point of no return' after which Cdc6 synthesis cannot promote DNA replication in yeast
    • 1 defines a 'point of no return' after which Cdc6 synthesis cannot promote DNA replication in yeast. Genes Dev. 10:1996;1516-1531.
    • (1996) Genes Dev , vol.10 , pp. 1516-1531
    • Piatti, S.1    Bohm, T.2    Cocker, J.H.3    Diffley, J.F.X.4    Nasmyth, K.5
  • 8
    • 0028800378 scopus 로고
    • CLN3, not positive feedback, determines the timing of CLN2 transcription in cycling cell
    • Stuart D, Wittenberg C. CLN3, not positive feedback, determines the timing of CLN2 transcription in cycling cell. Genes Dev. 9:1995;2780-2794.
    • (1995) Genes Dev , vol.9 , pp. 2780-2794
    • Stuart, D.1    Wittenberg, C.2
  • 9
    • 0029099463 scopus 로고
    • Roles and regulation of Cln - Cdc28 kinases at the start of the cell cycle of Saccharomyces cerevisiae
    • of special interest. CLN3, but not CLN1 and CLN2, activates SBF (and MBF) regulated gene expression (see also [8]). In contrast, the cell size at which cells acquire resistance to pheromone, initiate the assembly of a daughter bud, and commence DNA replication is determined by the level of CLN1 and CLN2 activity. The prolonged delay of S phase in cln1 cln2 mutants is suppressed by deletion of SIC1, which is consistent with the observation that CLNs are dispensable in a sic1 mutant [27, 28]. This study provides clear evidence that CLN3 and CLN1/CLN2 perform distinct functions in wild-type cells.
    • Dirick L, Böhm T, Nasmyth K. Roles and regulation of Cln - Cdc28 kinases at the start of the cell cycle of Saccharomyces cerevisiae. of special interest EMBO J. 14:1995;4803-4813 CLN3, but not CLN1 and CLN2, activates SBF (and MBF) regulated gene expression (see also [8]). In contrast, the cell size at which cells acquire resistance to pheromone, initiate the assembly of a daughter bud, and commence DNA replication is determined by the level of CLN1 and CLN2 activity. The prolonged delay of S phase in cln1 cln2 mutants is suppressed by deletion of SIC1, which is consistent with the observation that CLNs are dispensable in a sic1 mutant [27, 28]. This study provides clear evidence that CLN3 and CLN1/CLN2 perform distinct functions in wild-type cells.
    • (1995) EMBO J , vol.14 , pp. 4803-4813
    • Dirick, L.1    Böhm, T.2    Nasmyth, K.3
  • 10
    • 0026610360 scopus 로고
    • Regulation of p34CDC28 tyrosine phosphorylation is not required for entry into mitosis in S. cerevisiae
    • Amon A, Surana U, Muroff I, Nasmyth K. Regulation of p34CDC28 tyrosine phosphorylation is not required for entry into mitosis in S. cerevisiae. Nature. 355:1992;368-371.
    • (1992) Nature , vol.355 , pp. 368-371
    • Amon, A.1    Surana, U.2    Muroff, I.3    Nasmyth, K.4
  • 11
    • 0023053590 scopus 로고
    • Schizosaccharomyces pombe and Saccharmomyces cerevisiae - A look at yeast divided
    • Russell P, Nurse P. Schizosaccharomyces pombe and Saccharmomyces cerevisiae - a look at yeast divided. Cell. 45:1986;781-782.
    • (1986) Cell , vol.45 , pp. 781-782
    • Russell, P.1    Nurse, P.2
  • 12
    • 0023712476 scopus 로고
    • The RAD9 gene controls the cell cycle response to DNA damage in Saccharomyces cerevisiae
    • Weinert TA, Hartwell LH. The RAD9 gene controls the cell cycle response to DNA damage in Saccharomyces cerevisiae. Science. 241:1988;322-371.
    • (1988) Science , vol.241 , pp. 322-371
    • Weinert, T.A.1    Hartwell, L.H.2
  • 13
    • 0025726792 scopus 로고
    • Uptake of endocytic markers into mitotic yeast cells
    • Nevalainen LT, Makarow M. Uptake of endocytic markers into mitotic yeast cells. FEBS Lett. 282:1991;166-169.
    • (1991) FEBS Lett , vol.282 , pp. 166-169
    • Nevalainen, L.T.1    Makarow, M.2
  • 14
    • 0028788937 scopus 로고
    • Budding yeast morphogenesis: Signalling, cytoskeleton and cell cycle
    • Kron SJ, Gow NA. Budding yeast morphogenesis: signalling, cytoskeleton and cell cycle. Curr Opin Cell Biol. 7:1995;845-855.
    • (1995) Curr Opin Cell Biol , vol.7 , pp. 845-855
    • Kron, S.J.1    Gow, N.A.2
  • 15
    • 0028915943 scopus 로고
    • A cell cycle checkpoint monitors cell morphogenesis in budding yeast
    • Lew DJ, Reed SI. A cell cycle checkpoint monitors cell morphogenesis in budding yeast. J Cell Biol. 129:1995;739-749.
    • (1995) J Cell Biol , vol.129 , pp. 739-749
    • Lew, D.J.1    Reed, S.I.2
  • 16
    • 0025291669 scopus 로고
    • Mitotic role for the Cdc28 protein kinase of Sacchraromyces cerevisiae
    • Reed SI, Wittenberg C. Mitotic role for the Cdc28 protein kinase of Sacchraromyces cerevisiae. Proc Natl Acad Sci USA. 87:1990;5697-5701.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 5697-5701
    • Reed, S.I.1    Wittenberg, C.2
  • 17
    • 0030052137 scopus 로고    scopus 로고
    • From DNA damage to cell cycle arrest and suicide: A budding yeast perspective
    • Lydall D, Weinert T. From DNA damage to cell cycle arrest and suicide: a budding yeast perspective. Curr Opin Genet Dev. 6:1996;4-11.
    • (1996) Curr Opin Genet Dev , vol.6 , pp. 4-11
    • Lydall, D.1    Weinert, T.2
  • 18
    • 0029670828 scopus 로고    scopus 로고
    • 1 cyclins.
    • of special interest. Repeated rounds of DNA replication that occur upon depletion of CDC13 (S. pombe cyclin B) require the CIG1 and CIG2 cyclins. S phase is postponed in cig1 cig2 cells until CDC13 begins to accumulate, and CDC13-depleted cig1 cig2 cells are unable to replicate DNA, suggesting that the mitotic cyclin CDC13 promotes both DNA synthesis and mitosis in the absence of CIG1 and CIG2 function. It is proposed that low levels of CDC13/CDK activity trigger S phase in cig1 cig2 cells, whereas high levels are required to trigger mitosis. It remains unclear whether other unidentified cyclins collaborate with CDC13 to effect S and M phase.
    • 1 cyclins. of special interest EMBO J. 15:1996;850-860 Repeated rounds of DNA replication that occur upon depletion of CDC13 (S. pombe cyclin B) require the CIG1 and CIG2 cyclins. S phase is postponed in cig1 cig2 cells until CDC13 begins to accumulate, and CDC13-depleted cig1 cig2 cells are unable to replicate DNA, suggesting that the mitotic cyclin CDC13 promotes both DNA synthesis and mitosis in the absence of CIG1 and CIG2 function. It is proposed that low levels of CDC13/CDK activity trigger S phase in cig1 cig2 cells, whereas high levels are required to trigger mitosis. It remains unclear whether other unidentified cyclins collaborate with CDC13 to effect S and M phase.
    • (1996) EMBO J , vol.15 , pp. 850-860
    • Fisher, D.L.1    Nurse, P.2
  • 20
    • 0029082391 scopus 로고
    • 1 is important for the onset of S phase and for preventing a 'reduction' anaphase in the budding yeast saccharomyces cerevisiae
    • 1 is important for the onset of S phase and for preventing a 'reduction' anaphase in the budding yeast saccharomyces cerevisiae. EMBO J. 14:1995;3788-3799.
    • (1995) EMBO J , vol.14 , pp. 3788-3799
    • Piatti, S.1    Lengauer, C.2    Nasmyth, K.3
  • 21
    • 0026699308 scopus 로고
    • CLB5: A novel B cyclin from budding yeast with a role in S phase
    • Epstein CB, Cross FR. CLB5: a novel B cyclin from budding yeast with a role in S phase. Genes Dev. 6:1992;1695-1706.
    • (1992) Genes Dev , vol.6 , pp. 1695-1706
    • Epstein, C.B.1    Cross, F.R.2
  • 22
    • 0027220020 scopus 로고
    • CLB5 and CLB6, a new pair of B cyclins involved in DNA replication in Saccharomyces cerevisiae
    • Schwob E, Nasmyth K. CLB5 and CLB6, a new pair of B cyclins involved in DNA replication in Saccharomyces cerevisiae. Genes Dev. 7:1993;1160-1175.
    • (1993) Genes Dev , vol.7 , pp. 1160-1175
    • Schwob, E.1    Nasmyth, K.2
  • 24
    • 0029033504 scopus 로고
    • Genes involved in sister chromatid separation are needed for B-type cyclin proteolysis in building yeast
    • Irniger S, Piatti S, Michaelis C, Nasmyth K. Genes involved in sister chromatid separation are needed for B-type cyclin proteolysis in building yeast. Cell. 81:1995;269-277.
    • (1995) Cell , vol.81 , pp. 269-277
    • Irniger, S.1    Piatti, S.2    Michaelis, C.3    Nasmyth, K.4
  • 25
    • 0029791262 scopus 로고    scopus 로고
    • The transcription factor SWI5 regulates expression of the cyclin kinase inhibitor p40SIC1
    • Knapp D, Bhoite L, Stillman DJ, Nasmyth K. The transcription factor SWI5 regulates expression of the cyclin kinase inhibitor p40SIC1. Mol Cell Biol. 16:1996;5701-5707.
    • (1996) Mol Cell Biol , vol.16 , pp. 5701-5707
    • Knapp, D.1    Bhoite, L.2    Stillman, D.J.3    Nasmyth, K.4
  • 27
    • 0029923035 scopus 로고    scopus 로고
    • Linkage of replication to START by the CDK inhibitor Sic1
    • of special interest. CLN and CDC34 function are shown to be interdependent, implying a direct role for CLN/CDC28 activity in the maintenance of SIC1 proteolysis. Unexpected, deletion of SIC1 bypasses the essential requirement for CLN function, which suggests that the activation of SIC1 proteolysis is the sole non-redundant essential function of CLNs. Mutant sic1 cells enter S phase precociously; thus, SIC1 appears to play a crucial role in restraining S phase.
    • Schneider BL, Yang QH, Futcher AB. Linkage of replication to START by the CDK inhibitor Sic1. of special interest Science. 272:1996;560-562 CLN and CDC34 function are shown to be interdependent, implying a direct role for CLN/CDC28 activity in the maintenance of SIC1 proteolysis. Unexpected, deletion of SIC1 bypasses the essential requirement for CLN function, which suggests that the activation of SIC1 proteolysis is the sole non-redundant essential function of CLNs. Mutant sic1 cells enter S phase precociously; thus, SIC1 appears to play a crucial role in restraining S phase.
    • (1996) Science , vol.272 , pp. 560-562
    • Schneider, B.L.1    Yang, Q.H.2    Futcher, A.B.3
  • 28
    • 0029842867 scopus 로고    scopus 로고
    • 1 cyclin function at Start
    • 1 cyclin function at Start. Proc Natl Acad Sci USA. 93:1996;7772-7776.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 7772-7776
    • Tyers, M.1
  • 29
    • 0030602813 scopus 로고    scopus 로고
    • SKP1 connects cell cycle regulators to the ubiquitin proteolysis machinery through a novel motif, the F-box
    • ts cells also arrest in mitosis, perhaps because of the participation of SKP1 in the kinetochore-binding CBF3 complex [39,40]
    • ts cells also arrest in mitosis, perhaps because of the participation of SKP1 in the kinetochore-binding CBF3 complex [39,40].
    • (1996) Cell , vol.86 , pp. 263-274
    • Bai, C.1    Sen, P.2    Hofmann, K.3    Ma, L.4    Goebl, M.5    Harper, J.W.6    Elledge, S.J.7
  • 31
    • 0030576515 scopus 로고    scopus 로고
    • 1 cyclins for degradation by the ubiquitin proteolytic pathway
    • of special interest. CDC53 is a tightly-bound subunit of CLN2/CDC28 complexes. CDC53 also binds the ubiquitin-conjugating enzyme CDC34 and like CDC34 is required for rapid proteolysis of phosphorylated CLN2. CDC53 associates with phosphorylated CLN2, which is unstable, but not with unmodified CLN2, which is stable. Taken together, these results suggest that CDC53 targets phosphorylated CLN2 for CDC34-dependent ubiquitination.
    • 1 cyclins for degradation by the ubiquitin proteolytic pathway. of special interest Cell. 86:1996;453-463 CDC53 is a tightly-bound subunit of CLN2/CDC28 complexes. CDC53 also binds the ubiquitin-conjugating enzyme CDC34 and like CDC34 is required for rapid proteolysis of phosphorylated CLN2. CDC53 associates with phosphorylated CLN2, which is unstable, but not with unmodified CLN2, which is stable. Taken together, these results suggest that CDC53 targets phosphorylated CLN2 for CDC34-dependent ubiquitination.
    • (1996) Cell , vol.86 , pp. 453-463
    • Willems, A.R.1    Lanker, S.2    Patton, E.E.3    Craig, K.L.4    Nason, T.F.5    Kobayashi, R.6    Wittenberg, C.7    Tyers, M.8
  • 33
    • 0029953780 scopus 로고    scopus 로고
    • Cul-1 is required for cell cycle exit in C. elegans and identifies a novel gene family
    • of special interest. A nematode gene, cul-1, which is required to limit cell divisions during embryonic development is found to be closely related to CDC53. Expressed sequence tag databank searches reveal that CDC53 and cul-1 are members of a multigene family conserved from budding yeast to humans. Humans express at least six CDC53 homologs, which are dubbed 'cullins'.
    • Kipreos ET, Lander LE, Wing JP, He WW, Hedgecock EM. cul-1 is required for cell cycle exit in C. elegans and identifies a novel gene family. of special interest Cell. 85:1996;1-20 A nematode gene, cul-1, which is required to limit cell divisions during embryonic development is found to be closely related to CDC53. Expressed sequence tag databank searches reveal that CDC53 and cul-1 are members of a multigene family conserved from budding yeast to humans. Humans express at least six CDC53 homologs, which are dubbed 'cullins'.
    • (1996) Cell , vol.85 , pp. 1-20
    • Kipreos, E.T.1    Lander, L.E.2    Wing, J.P.3    He, W.W.4    Hedgecock, E.M.5
  • 34
    • 0028980273 scopus 로고
    • P19(SKP1) and p45(SKP2) are essential elements of the cyclin A - CK2 S phase kinase
    • Zhang H, Kobayashi R, Galaktionov K, Beach D. p19(SKP1) and p45(SKP2) are essential elements of the cyclin A - CK2 S phase kinase. Cell. 82:1995;912-925.
    • (1995) Cell , vol.82 , pp. 912-925
    • Zhang, H.1    Kobayashi, R.2    Galaktionov, K.3    Beach, D.4
  • 35
    • 0028076764 scopus 로고
    • The ancient regulatory-protein family of WD-repeat proteins
    • Neer EJ, Schmidt CJ, Nambudripad R, Smith TF. The ancient regulatory-protein family of WD-repeat proteins. Nature. 371:1994;297-300.
    • (1994) Nature , vol.371 , pp. 297-300
    • Neer, E.J.1    Schmidt, C.J.2    Nambudripad, R.3    Smith, T.F.4
  • 37
    • 0028607143 scopus 로고
    • Regulated degradation of the transcription factor GCN4
    • Kornitzer D, Raboy B, Kulka RG, Fink GR. Regulated degradation of the transcription factor GCN4. EMBO J. 13:1994;6021-6030.
    • (1994) EMBO J , vol.13 , pp. 6021-6030
    • Kornitzer, D.1    Raboy, B.2    Kulka, R.G.3    Fink, G.R.4
  • 38
    • 0028986667 scopus 로고
    • G(1) cyclin turnover and nutrient-uptake are controlled by a common pathway in yeast
    • Barral Y, Jentsch S, Mann C. G(1) cyclin turnover and nutrient-uptake are controlled by a common pathway in yeast. Genes Dev. 9:1995;399-409.
    • (1995) Genes Dev , vol.9 , pp. 399-409
    • Barral, Y.1    Jentsch, S.2    Mann, C.3
  • 39
    • 0030602823 scopus 로고    scopus 로고
    • Budding yeast SKP1 encodes an evolutionary conserved kinetochore protein required for cell cycle progression
    • Connelly C, Hieter P. Budding yeast SKP1 encodes an evolutionary conserved kinetochore protein required for cell cycle progression. Cell. 86:1996;275-285.
    • (1996) Cell , vol.86 , pp. 275-285
    • Connelly, C.1    Hieter, P.2
  • 40
    • 0029977360 scopus 로고    scopus 로고
    • The Saccharomyces cerevisiae kinetochore contains a cyclin-cdk complexing homolog as identified by in vitro reconstitution
    • Stemmann O, Lechner J. The Saccharomyces cerevisiae kinetochore contains a cyclin-cdk complexing homolog as identified by in vitro reconstitution. EMBO J. 15:1996;3611-3620.
    • (1996) EMBO J , vol.15 , pp. 3611-3620
    • Stemmann, O.1    Lechner, J.2
  • 41
    • 0029114757 scopus 로고
    • Genetic and biochemical interactions between an essential kinetochore protein, Cbf2p/Ndc10p, and the CDC34 ubiquitin-conjugating enzyme
    • Yoon H-J, Carbon J. Genetic and biochemical interactions between an essential kinetochore protein, Cbf2p/Ndc10p, and the CDC34 ubiquitin-conjugating enzyme. Mol Cell Biol. 15:1995;4835-4842.
    • (1995) Mol Cell Biol , vol.15 , pp. 4835-4842
    • Yoon, H.-J.1    Carbon, J.2
  • 43
    • 0029670193 scopus 로고    scopus 로고
    • 1 cyclin Cln2 induced by CDK-dependent phosphorylation
    • 4T3S polypeptide, which is seven-fold more stable than wild-type CLN2.
    • 4T3S polypeptide, which is seven-fold more stable than wild-type CLN2.
    • (1996) Science , vol.271 , pp. 1597-1601
    • Lanker, S.1    Valdivieso, M.H.2    Wittenberg, C.3
  • 44
    • 0029787091 scopus 로고    scopus 로고
    • Mutagenic analysis of the destruction signal of mitotic cyclins and structural characterization of ubiquitinated intermediates
    • King RW, Glotzer M, Kirschner MW. Mutagenic analysis of the destruction signal of mitotic cyclins and structural characterization of ubiquitinated intermediates. Mol Biol Cell. 7:1996;1343-1357.
    • (1996) Mol Biol Cell , vol.7 , pp. 1343-1357
    • King, R.W.1    Glotzer, M.2    Kirschner, M.W.3
  • 46
    • 0029004815 scopus 로고
    • A 20S complex containing CDC27 and CDC16 catalyzes the mitosis-specific conjugation of ubiquitin to cyclin B
    • King RW, Peters JM, Tugendreich S, Rolfe M, Hieter P, Kirschner MW. A 20S complex containing CDC27 and CDC16 catalyzes the mitosis-specific conjugation of ubiquitin to cyclin B. Cell. 81:1995;279-288.
    • (1995) Cell , vol.81 , pp. 279-288
    • King, R.W.1    Peters, J.M.2    Tugendreich, S.3    Rolfe, M.4    Hieter, P.5    Kirschner, M.W.6
  • 47
    • 0030113930 scopus 로고    scopus 로고
    • Identification of a novel ubiquitin-conjugating enzyme involved in mitotic cyclin degradation
    • Yu H, King RW, Peters J-M, Kirschner MW. Identification of a novel ubiquitin-conjugating enzyme involved in mitotic cyclin degradation. Curr Biol. 6:1996;455-466.
    • (1996) Curr Biol , vol.6 , pp. 455-466
    • Yu, H.1    King, R.W.2    Peters, J.-M.3    Kirschner, M.W.4
  • 48
    • 0029025606 scopus 로고
    • The cyclosome, a large complex containing cyclin-selective ubiquitin ligase activity, targets cyclins for destruction at the end of mitosis
    • Sudakin V, Ganoth D, Dahan A, Heller H, Hershko J, Luca FC, Ruderman JV, Hershko A. The cyclosome, a large complex containing cyclin-selective ubiquitin ligase activity, targets cyclins for destruction at the end of mitosis. Mol Biol Cell. 6:1995;185-197.
    • (1995) Mol Biol Cell , vol.6 , pp. 185-197
    • Sudakin, V.1    Ganoth, D.2    Dahan, A.3    Heller, H.4    Hershko, J.5    Luca, F.C.6    Ruderman, J.V.7    Hershko, A.8
  • 49
    • 0029863734 scopus 로고    scopus 로고
    • E2-C, a cyclin-selective ubiquitin carrier protein required for the destruction of mitotic cylins
    • Aristarkhov A, Eytan E, Moghe A, Admon A, Hersko A, Ruderman JV. E2-C, a cyclin-selective ubiquitin carrier protein required for the destruction of mitotic cylins. Proc Natl Acad Sci USA. 93:1996;4294-4299.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 4294-4299
    • Aristarkhov, A.1    Eytan, E.2    Moghe, A.3    Admon, A.4    Hersko, A.5    Ruderman, J.V.6
  • 50
    • 0343829343 scopus 로고    scopus 로고
    • Identification of subunits of the anaphase-promoting complex of Saccharomyces cerevisiae
    • Zachariae W, Shin TH, Galova M, Obermaier B, Nasmyth K. Identification of subunits of the anaphase-promoting complex of Saccharomyces cerevisiae. Science. 274:1996;1201-1204.
    • (1996) Science , vol.274 , pp. 1201-1204
    • Zachariae, W.1    Shin, T.H.2    Galova, M.3    Obermaier, B.4    Nasmyth, K.5
  • 51
    • 85030289838 scopus 로고    scopus 로고
    • Identification of BIME as a subunit of the anaphase-promoting complex
    • in press
    • Peters J-M, King RW, Höög C, Kirschner MW. Identification of BIME as a subunit of the anaphase-promoting complex. Science. 1997;. in press.
    • (1997) Science
    • Peters, J.-M.1    King, R.W.2    Höög, C.3    Kirschner, M.W.4
  • 52
    • 0029924373 scopus 로고    scopus 로고
    • TPR proteins required for anaphase progression mediate ubiquitination of mitotic B-type cyclins in yeast
    • Zachariae W, Nasmyth K. TPR proteins required for anaphase progression mediate ubiquitination of mitotic B-type cyclins in yeast. Mol Biol Cell. 7:1996;791-806.
    • (1996) Mol Biol Cell , vol.7 , pp. 791-806
    • Zachariae, W.1    Nasmyth, K.2
  • 54
    • 0028958186 scopus 로고
    • The Drosophila cell cycle gene fizzy is required for normal degradation of cyclins A and B during mitosis and has homology to the CDC20 gene of Saccharomyces cerevisiae
    • Dawson IA, Roth S, Artavanis-Tsakonas S. The Drosophila cell cycle gene fizzy is required for normal degradation of cyclins A and B during mitosis and has homology to the CDC20 gene of Saccharomyces cerevisiae. J Cell Biol. 129:1995;725-737.
    • (1995) J Cell Biol , vol.129 , pp. 725-737
    • Dawson, I.A.1    Roth, S.2    Artavanis-Tsakonas, S.3
  • 55
    • 0029964613 scopus 로고    scopus 로고
    • Requirement for cAMP-PKA pathway activation by M phase-promoting factor in the transition from mitosis to interphase
    • Grieco D, Porcellini A, Awedimento EV, Gottesman ME. Requirement for cAMP-PKA pathway activation by M phase-promoting factor in the transition from mitosis to interphase. Science. 271:1996;1718-1723.
    • (1996) Science , vol.271 , pp. 1718-1723
    • Grieco, D.1    Porcellini, A.2    Awedimento, E.V.3    Gottesman, M.E.4
  • 56
    • 0029917506 scopus 로고    scopus 로고
    • The yeast CDC16 and CDC27 genes restrict DNA replication to once per cell cycle
    • Heichman KA, Roberts JM. The yeast CDC16 and CDC27 genes restrict DNA replication to once per cell cycle. Cell. 85:1996;39-48.
    • (1996) Cell , vol.85 , pp. 39-48
    • Heichman, K.A.1    Roberts, J.M.2
  • 57
    • 0027319328 scopus 로고
    • Anaphase is initiated by proteolysis rather than by the inactivation of maturation-promoting factor
    • Holloway SL, Glotzer M, King RW, Murray AW. Anaphase is initiated by proteolysis rather than by the inactivation of maturation-promoting factor. Cell. 73:1993;1393-1402.
    • (1993) Cell , vol.73 , pp. 1393-1402
    • Holloway, S.L.1    Glotzer, M.2    King, R.W.3    Murray, A.W.4
  • 58
    • 0029960782 scopus 로고    scopus 로고
    • Pds1p, an inhibitor of anaphase in budding yeast, plays a critical role in the anaphase and checkpoint pathway(s)
    • of special interest. A pds mutant is identified among a collection of mutants that fail to survive transient exposure to nocodazole. FISH analysis reveals that PDS1 is required to maintain chromatid cohesion in nocodazole-arrested cells. Deletion of PDS1 relieves the metaphase arrest caused by damaged and incompletely replicated DNA or mutation of APC subunits. Coupled with [59], which establishes that PDS1 is an authentic APC substrate, these data suggest that PDS1 may correspond to the sister chromatid cohesion regulator hypothesized by Holloway et al. [57].
    • Yamamoto A, Guacci V, Koshland D. Pds1p, an inhibitor of anaphase in budding yeast, plays a critical role in the anaphase and checkpoint pathway(s). of special interest J Cell Biol. 133:1996;99-110 A pds mutant is identified among a collection of mutants that fail to survive transient exposure to nocodazole. FISH analysis reveals that PDS1 is required to maintain chromatid cohesion in nocodazole-arrested cells. Deletion of PDS1 relieves the metaphase arrest caused by damaged and incompletely replicated DNA or mutation of APC subunits. Coupled with [59], which establishes that PDS1 is an authentic APC substrate, these data suggest that PDS1 may correspond to the sister chromatid cohesion regulator hypothesized by Holloway et al. [57].
    • (1996) J Cell Biol , vol.133 , pp. 99-110
    • Yamamoto, A.1    Guacci, V.2    Koshland, D.3
  • 59
    • 0030448251 scopus 로고    scopus 로고
    • Anaphase initiation in Saccharomyces cerevisiae is controlled by the APC-dependent degradation of the anaphase inhibitor, Pds1p
    • of special interest. Degradation of PDS1 in yeast cells and in Xenopus extract requires both an intact destruction box and APC activity. PDS1 is ubiquitinated in the presence of purified APC and UBC4 or UBC-x. The destruction of PDS1 in vivo correlates with the onset of anaphase, and a mutant of PDS1 lacking a destruction box-like sequence (PDS1-ΔDB) causes a substantial delay in chromosome segregation, anaphase spindle elongation, and cell division. These phenotypes do not arise from a complete shutdown of APC as wild-type PDS1 is destroyed on schedule in cells expressing PDS1-ΔDB. These data, in conjunction with those of Yamamoto et al. [58] constitute the best evidence to date for the existence of APC-sensitive anaphase inhibitors.
    • Cohen-Fix O, Peters J-M, Kirschner MW, Koshland D. Anaphase initiation in Saccharomyces cerevisiae is controlled by the APC-dependent degradation of the anaphase inhibitor, Pds1p. of special interest Genes Dev. 10:1996;3081-3093 Degradation of PDS1 in yeast cells and in Xenopus extract requires both an intact destruction box and APC activity. PDS1 is ubiquitinated in the presence of purified APC and UBC4 or UBC-x. The destruction of PDS1 in vivo correlates with the onset of anaphase, and a mutant of PDS1 lacking a destruction box-like sequence (PDS1-ΔDB) causes a substantial delay in chromosome segregation, anaphase spindle elongation, and cell division. These phenotypes do not arise from a complete shutdown of APC as wild-type PDS1 is destroyed on schedule in cells expressing PDS1-ΔDB. These data, in conjunction with those of Yamamoto et al. [58] constitute the best evidence to date for the existence of APC-sensitive anaphase inhibitors.
    • (1996) Genes Dev , vol.10 , pp. 3081-3093
    • Cohen-Fix, O.1    Peters, J.-M.2    Kirschner, M.W.3    Koshland, D.4
  • 60
    • 0030013594 scopus 로고    scopus 로고
    • Cut2 proteolysis required for sister-chromatid separation in fission yeast
    • 1-arrested cells unless APC is mutated or the destruction box sequences of CUT2 are deleted (CUT2-ΔDB). Expression of CUTΔDB blocks sister chromosome segregation but does not block the exit from mitosis. These defects appear to be caused by the increased stability of CUT2-ΔDB because they can be complemented by grafting the destruction-box-containing amino terminus of CDC13 onto CUT2-ΔDB.
    • 1-arrested cells unless APC is mutated or the destruction box sequences of CUT2 are deleted (CUT2-ΔDB). Expression of CUTΔDB blocks sister chromosome segregation but does not block the exit from mitosis. These defects appear to be caused by the increased stability of CUT2-ΔDB because they can be complemented by grafting the destruction-box-containing amino terminus of CDC13 onto CUT2-ΔDB.
    • (1996) Nature , vol.381 , pp. 438-441
    • Funabiki, H.1    Yamano, H.2    Kumada, K.3    Nagao, K.4    Hunt, T.5    Yanagida, M.6
  • 61
    • 0029157332 scopus 로고
    • Two microtubule-associated proteins required for anaphase spindle movement in Saccharomyces cerevisiae
    • Pellman D, Bagget M, Tu H, Fink GR. Two microtubule-associated proteins required for anaphase spindle movement in Saccharomyces cerevisiae. J Cell Biol. 130:1995;1373-1385.
    • (1995) J Cell Biol , vol.130 , pp. 1373-1385
    • Pellman, D.1    Bagget, M.2    Tu, H.3    Fink, G.R.4
  • 62
    • 0028304675 scopus 로고
    • Type 1 protein phosphatase acts in opposition to Ip11 protein kinase in regulating yeast chromosome segregation
    • Francisco L, Wang W, Chan CSM. Type 1 protein phosphatase acts in opposition to Ip11 protein kinase in regulating yeast chromosome segregation. Mol Cell Biol. 14:1994;4731-4740.
    • (1994) Mol Cell Biol , vol.14 , pp. 4731-4740
    • Francisco, L.1    Wang, W.2    Chan, C.S.M.3
  • 63
    • 0028865511 scopus 로고
    • Regulation of chromosome segregation by Glc8p, a structural homolog of mammalian inhibitor 2 that functions as both an activator and an inhibitor of yeast protein phosphatase 1
    • Tung HYL, Wang W, Chan CSM. Regulation of chromosome segregation by Glc8p, a structural homolog of mammalian inhibitor 2 that functions as both an activator and an inhibitor of yeast protein phosphatase 1. Mol Cell Biol. 15:1995;6064-6074.
    • (1995) Mol Cell Biol , vol.15 , pp. 6064-6074
    • Tung, H.Y.L.1    Wang, W.2    Chan, C.S.M.3
  • 65
    • 0028962292 scopus 로고
    • The genetics of cell cycle checkpoints
    • Murray AW. The genetics of cell cycle checkpoints. Curr Opin Genet Dev. 5:1995;5-11.
    • (1995) Curr Opin Genet Dev , vol.5 , pp. 5-11
    • Murray, A.W.1
  • 66
    • 0028822203 scopus 로고
    • Single stranded DNA arising at telomeres in cdc13 mutants may constitute a specific signal for the RAD9 checkpoint
    • Garvik B, Carson M, Hartwell L. Single stranded DNA arising at telomeres in cdc13 mutants may constitute a specific signal for the RAD9 checkpoint. Mol Cell Biol. 15:1995;6128-6138.
    • (1995) Mol Cell Biol , vol.15 , pp. 6128-6138
    • Garvik, B.1    Carson, M.2    Hartwell, L.3
  • 67
    • 0028219886 scopus 로고
    • The Dbf2 and Dbf20 protein kinases of budding yeast are activated after the metaphase to anaphase cell cycle transition
    • Toyn JH, Johnston LH. The Dbf2 and Dbf20 protein kinases of budding yeast are activated after the metaphase to anaphase cell cycle transition. EMBO J. 13:1994;1103-1113.
    • (1994) EMBO J , vol.13 , pp. 1103-1113
    • Toyn, J.H.1    Johnston, L.H.2
  • 68
    • 0028062930 scopus 로고
    • The yeast TEM1 gene, which encodes a GTP-binding protein, is involved in termination of M phase
    • Shirayama M, Matsui Y, Tohe A. The yeast TEM1 gene, which encodes a GTP-binding protein, is involved in termination of M phase. Mol Cell Biol. 14:1994;7476-7482.
    • (1994) Mol Cell Biol , vol.14 , pp. 7476-7482
    • Shirayama, M.1    Matsui, Y.2    Tohe, A.3
  • 70
    • 0025034980 scopus 로고
    • Intercellular and extracellular levels of cyclic AMP during the cell cycle of Saccharomyces cerevisiae
    • Smith ME, Dickinson JR, Wheals AE. Intercellular and extracellular levels of cyclic AMP during the cell cycle of Saccharomyces cerevisiae. Yeast. 6:1990;53-60.
    • (1990) Yeast , vol.6 , pp. 53-60
    • Smith, M.E.1    Dickinson, J.R.2    Wheals, A.E.3
  • 72
    • 0027237551 scopus 로고
    • Saccharomyces cerevisiae cdc15 mutants arrested at a late stage in anaphase are rescued by Xenopus cDNAs encoding N-ras or a protein with β-transducin repeats
    • Spevak W, Keiper BD, Stratowa C, Castanon MJ. Saccharomyces cerevisiae cdc15 mutants arrested at a late stage in anaphase are rescued by Xenopus cDNAs encoding N-ras or a protein with β-transducin repeats. Mol Cell Biol. 13:1993;4953-4966.
    • (1993) Mol Cell Biol , vol.13 , pp. 4953-4966
    • Spevak, W.1    Keiper, B.D.2    Stratowa, C.3    Castanon, M.J.4
  • 73
    • 0023442858 scopus 로고
    • Rigorous feedback control of cAMP levels in Saccharomyces cerevisiae
    • Nikawa J-I, Cameron S, Toda T, Ferguson KM, Wigler M. Rigorous feedback control of cAMP levels in Saccharomyces cerevisiae. Genes Dev. 1:1987;931-937.
    • (1987) Genes Dev , vol.1 , pp. 931-937
    • Nikawa, J.-I.1    Cameron, S.2    Toda, T.3    Ferguson, K.M.4    Wigler, M.5
  • 74
  • 75
    • 0029155542 scopus 로고
    • Spindle dynamics and cell cycle regulation of dynein in the budding yeast, Saccharomyces cerevisiae
    • of special interest. Anaphase spindle dynamics in wild-type and dynein heavy-chain-deficient (dhc1 Δ) cells are monitored in real time using video-enhanced differential interference contrast microscopy. The observations on wild-type cells are similar to those reported by Kahana et al. [74]. In dhc1Δ cells that fail to localize the nucleus to the mother-bud junction, the nucleus undergoes anaphase entirely within the mother cell. Direct observation of anaphase in these cells reveals the existence of a checkpoint that restrains cytokinesis until the extended nucleus is translocated across the mother-bud junction.
    • Yeh E, Skibbens RV, Cheng JW, Salmon ED, Bloom K. Spindle dynamics and cell cycle regulation of dynein in the budding yeast, Saccharomyces cerevisiae. of special interest J Cell Biol. 130:1995;687-700 Anaphase spindle dynamics in wild-type and dynein heavy-chain-deficient (dhc1 Δ) cells are monitored in real time using video-enhanced differential interference contrast microscopy. The observations on wild-type cells are similar to those reported by Kahana et al. [74]. In dhc1Δ cells that fail to localize the nucleus to the mother-bud junction, the nucleus undergoes anaphase entirely within the mother cell. Direct observation of anaphase in these cells reveals the existence of a checkpoint that restrains cytokinesis until the extended nucleus is translocated across the mother-bud junction.
    • (1995) J Cell Biol , vol.130 , pp. 687-700
    • Yeh, E.1    Skibbens, R.V.2    Cheng, J.W.3    Salmon, E.D.4    Bloom, K.5
  • 78
    • 0029956016 scopus 로고    scopus 로고
    • 1 cyclins in yeast
    • 1 cyclins in yeast. Nature. 384:1996;279-282.
    • (1996) Nature , vol.384 , pp. 279-282
    • Blondel, M.1    Mann, C.2
  • 79
    • 0029843496 scopus 로고    scopus 로고
    • Fission yeast Cut1 and Cut 2 are essential for sister chromatid separation, concentrate along the metaphase spindle and form large complexes
    • Funabiki H, Kumada K, Yanagida M. Fission yeast Cut1 and Cut 2 are essential for sister chromatid separation, concentrate along the metaphase spindle and form large complexes. EMBO J. 15:1996;6617-6628.
    • (1996) EMBO J , vol.15 , pp. 6617-6628
    • Funabiki, H.1    Kumada, K.2    Yanagida, M.3
  • 80
    • 0029826437 scopus 로고    scopus 로고
    • Requirement for PP1 phosphatase and 20S cyclosome/APC for the onset of anaphase is lessened by the dosage increase of a novel gene sds23+
    • Ishii K, Kumada K, Toda T, Yanagida M. Requirement for PP1 phosphatase and 20S cyclosome/APC for the onset of anaphase is lessened by the dosage increase of a novel gene sds23+. EMBO J. 15:1996;6629-6640.
    • (1996) EMBO J , vol.15 , pp. 6629-6640
    • Ishii, K.1    Kumada, K.2    Toda, T.3    Yanagida, M.4


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