-
1
-
-
0028860983
-
Anti-inflammatory, analgesic, antipyretic and related properties of meloxicam, a new nonsteroidal anti-inflammatory agent
-
Engelhardt G, Homma D, Schnitzler Chr and Utzmann R, Anti-inflammatory, analgesic, antipyretic and related properties of meloxicam, a new nonsteroidal anti-inflammatory agent. Inflamm Res 44: 423-433, 1995.
-
(1995)
Inflamm Res
, vol.44
, pp. 423-433
-
-
Engelhardt, G.1
Homma, D.2
Schnitzler, Chr.3
Utzmann, R.4
-
2
-
-
0012073092
-
Meloxicam, a potent inhibitor of adjuvant arthritis in the rat
-
Abstr. No. 110
-
Engelhardt G, Meloxicam, a potent inhibitor of adjuvant arthritis in the rat. Scand J Rheumatol 98: (Suppl) Abstr. No. 110, 1994.
-
(1994)
Scand J Rheumatol
, vol.98
, Issue.SUPPL.
-
-
Engelhardt, G.1
-
3
-
-
0005109137
-
A double blind placebo controlled study of 7.5 and 15 mg of meloxicam in patients with rheumatoid arthritis (RA)
-
Abstr. 111
-
Lemmel EM, Bolten W, Bourgos-Vargas R, Platt PN, Nissilä M, Sahlberg D, Bjorneboe O, Baumgartner H, Valat JP, Franchimont P, Distel M, Bluhmki E and Hanft G. A double blind placebo controlled study of 7.5 and 15 mg of meloxicam in patients with rheumatoid arthritis (RA). Scand J Rheumatol 98: (Suppl) Abstr. 111, 1994.
-
(1994)
Scand J Rheumatol
, vol.98
, Issue.SUPPL.
-
-
Lemmel, E.M.1
Bolten, W.2
Bourgos-Vargas, R.3
Platt, P.N.4
Nissilä, M.5
Sahlberg, D.6
Bjorneboe, O.7
Baumgartner, H.8
Valat, J.P.9
Franchimont, P.10
Distel, M.11
Bluhmki, E.12
Hanft, G.13
-
4
-
-
0005108124
-
A double blind placebo controlled study of three different doses of meloxicam in patients with osteoarthritis of the knee
-
Abstr. 117
-
Lund B, Distel M, Bluhmki E, A double blind placebo controlled study of three different doses of meloxicam in patients with osteoarthritis of the knee. Scand J Rheumatol 98: (Suppl) Abstr. 117, 1994.
-
(1994)
Scand J Rheumatol
, vol.98
, Issue.SUPPL.
-
-
Lund, B.1
Distel, M.2
Bluhmki, E.3
-
5
-
-
0004428513
-
Mode of action of aspirin and similar compounds
-
(Eds. Robinson HJ and Vane RJ). Raven Press, New York
-
Vane JR, Mode of action of aspirin and similar compounds. In: Prostaglandin Synthetase Inhibitors (Eds. Robinson HJ and Vane RJ), pp. 155-163. Raven Press, New York, 1974.
-
(1974)
Prostaglandin Synthetase Inhibitors
, pp. 155-163
-
-
Vane, J.R.1
-
6
-
-
0015237292
-
Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs
-
Vane JR, Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs. Nature New Biol 231: 232-235, 1971.
-
(1971)
Nature New Biol
, vol.231
, pp. 232-235
-
-
Vane, J.R.1
-
7
-
-
0001208476
-
Temporal and pharmacological division of fibroblast cyclooxygenase expression into transcriptional and translational phases
-
Raz A, Wyche A and Needleman P, Temporal and pharmacological division of fibroblast cyclooxygenase expression into transcriptional and translational phases. Proc Natl Acad Sci USA 86: 1657-1661, 1989.
-
(1989)
Proc Natl Acad Sci USA
, vol.86
, pp. 1657-1661
-
-
Raz, A.1
Wyche, A.2
Needleman, P.3
-
8
-
-
0025754779
-
Expression of a mitogen-responsive gene encoding prostaglandin synthase is regulated by RNA splicing
-
Xie W, Chipman JG, Robertson DL, Erikson RC and Simmons DL, Expression of a mitogen-responsive gene encoding prostaglandin synthase is regulated by RNA splicing. Proc Natl Acad Sci USA 88: 2692-2696, 1991.
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, pp. 2692-2696
-
-
Xie, W.1
Chipman, J.G.2
Robertson, D.L.3
Erikson, R.C.4
Simmons, D.L.5
-
9
-
-
0026588961
-
Mitogen-inducible prostaglandin GIH synthase: A new target for nonsteroidal anti-inflammatory drugs
-
Xie W, Robertson DL and Simmons DL, Mitogen-inducible prostaglandin GIH synthase: A new target for nonsteroidal anti-inflammatory drugs. Drug Devel Res 25: 249-265, 1992.
-
(1992)
Drug Devel Res
, vol.25
, pp. 249-265
-
-
Xie, W.1
Robertson, D.L.2
Simmons, D.L.3
-
10
-
-
0017094798
-
An enzyme isolated from arteries transforms prostaglandin endoperoxides to an unstable substance that inhibits platelet aggregation
-
Moncada S, Gryglewski R, Buntnig S and Vane JR, An enzyme isolated from arteries transforms prostaglandin endoperoxides to an unstable substance that inhibits platelet aggregation. Nature 263: 663-665, 1976.
-
(1976)
Nature
, vol.263
, pp. 663-665
-
-
Moncada, S.1
Gryglewski, R.2
Buntnig, S.3
Vane, J.R.4
-
11
-
-
0018904225
-
Selective inhibition of prostaglandin production in inflammatory exudates and gastric mucosa
-
Whittle BJR, Higgs GA, Eakins KE, Moncada S and Vane JR, Selective inhibition of prostaglandin production in inflammatory exudates and gastric mucosa. Nature 284: 271-273, 1980.
-
(1980)
Nature
, vol.284
, pp. 271-273
-
-
Whittle, B.J.R.1
Higgs, G.A.2
Eakins, K.E.3
Moncada, S.4
Vane, J.R.5
-
12
-
-
0027146692
-
Selectivity of nonsteroidal anti-inflammatory drugs as inhibitors of constitutive and inducible cyclooxygenase
-
Mitchell JA, Akarasereenont P, Thiemerman Chr, Flower R and Vane JR, Selectivity of nonsteroidal anti-inflammatory drugs as inhibitors of constitutive and inducible cyclooxygenase. Proc Natl Acad Sci USA 90: 11693-11697, 1994.
-
(1994)
Proc Natl Acad Sci USA
, vol.90
, pp. 11693-11697
-
-
Mitchell, J.A.1
Akarasereenont, P.2
Thiemerman, Chr.3
Flower, R.4
Vane, J.R.5
-
13
-
-
0028044609
-
Towards a better aspirin
-
Vane J, Towards a better aspirin. Nature 367: 215-216, 1994.
-
(1994)
Nature
, vol.367
, pp. 215-216
-
-
Vane, J.1
-
14
-
-
0027480087
-
Differential inhibition of prostaglandin endoperoxide synthase (cyclooxygenase) isozymes by aspirin and other nonsteroidal anti-inflammatory drugs
-
Meade EA, Smith WL and DeWitt DL, Differential inhibition of prostaglandin endoperoxide synthase (cyclooxygenase) isozymes by aspirin and other nonsteroidal anti-inflammatory drugs. J Biol Chem 268: 6610-6614, 1993.
-
(1993)
J Biol Chem
, vol.268
, pp. 6610-6614
-
-
Meade, E.A.1
Smith, W.L.2
DeWitt, D.L.3
-
15
-
-
0024452740
-
A review of gastric ulcer and gastroduodenal injury in normal volunteers receiving aspirin and other nonsteroidal anti-inflammatory drugs
-
Lanza FL, A review of gastric ulcer and gastroduodenal injury in normal volunteers receiving aspirin and other nonsteroidal anti-inflammatory drugs. Scand J Gastroenterol 24: 24-31, 1989.
-
(1989)
Scand J Gastroenterol
, vol.24
, pp. 24-31
-
-
Lanza, F.L.1
-
16
-
-
0028327671
-
Risk of upper gastrointestinal bleeding and perforation associated with individual non-steroidal anti-inflammatory drugs
-
Garcia Rodriguez LA and Jick H, Risk of upper gastrointestinal bleeding and perforation associated with individual non-steroidal anti-inflammatory drugs. Lancet 343: 769-772, 1994.
-
(1994)
Lancet
, vol.343
, pp. 769-772
-
-
Garcia Rodriguez, L.A.1
Jick, H.2
-
17
-
-
0028012449
-
Differential interactions of prostaglandin endoperoxide synthases with nonsteroidal anti-inflammatory drugs
-
Smith WL and DeWitt D, Differential interactions of prostaglandin endoperoxide synthases with nonsteroidal anti-inflammatory drugs. Curr Opin Invest Drugs 3: 1-11, 1994.
-
(1994)
Curr Opin Invest Drugs
, vol.3
, pp. 1-11
-
-
Smith, W.L.1
DeWitt, D.2
-
18
-
-
0027218634
-
Induction of prostaglandin endoperoxide synthase isoform-2 in ovine cotyledonary tissue during late gestation
-
Wimsatt J, Nathanielsz PW and Sirois J, Induction of prostaglandin endoperoxide synthase isoform-2 in ovine cotyledonary tissue during late gestation. Endocrinology 133: 1068-1073, 1993.
-
(1993)
Endocrinology
, vol.133
, pp. 1068-1073
-
-
Wimsatt, J.1
Nathanielsz, P.W.2
Sirois, J.3
-
19
-
-
0015796477
-
Quantitative determination of prostaglandins and malondialdehyde formed by the arachinate oxygenase (prostaglandin synthetase) system of bovine seminal vesicle
-
Flower RJ, Cheung HS and Cushman DW, Quantitative determination of prostaglandins and malondialdehyde formed by the arachinate oxygenase (prostaglandin synthetase) system of bovine seminal vesicle. Prostaglandins 4: 325-341, 1973.
-
(1973)
Prostaglandins
, vol.4
, pp. 325-341
-
-
Flower, R.J.1
Cheung, H.S.2
Cushman, D.W.3
-
20
-
-
0016195398
-
A simple radiochemical assay for prostaglandin synthetase
-
White HL and Glassman J, A simple radiochemical assay for prostaglandin synthetase. Prostaglandins 7: 123-129, 1974.
-
(1974)
Prostaglandins
, vol.7
, pp. 123-129
-
-
White, H.L.1
Glassman, J.2
-
22
-
-
0000063441
-
A fundamental formula in the statistics of biological assay, and some applications
-
Fieller EC, A fundamental formula in the statistics of biological assay, and some applications. Q J Pharm Pharmacol 17: 117-123, 1944.
-
(1944)
Q J Pharm Pharmacol
, vol.17
, pp. 117-123
-
-
Fieller, E.C.1
-
23
-
-
0025005862
-
The induction and suppression of prostaglandin H2 synthase (cyclooxygenase) in human monocytes
-
Fu JY, Masferrer JL, Seibert K, Raz A and Needleman P, The induction and suppression of prostaglandin H2 synthase (cyclooxygenase) in human monocytes. J Biol Chem 265: 16737-16740, 1990.
-
(1990)
J Biol Chem
, vol.265
, pp. 16737-16740
-
-
Fu, J.Y.1
Masferrer, J.L.2
Seibert, K.3
Raz, A.4
Needleman, P.5
-
24
-
-
0026662385
-
Dexamethasone inhibits mitogen induction of the TIS 10 prostaglandin synthase cyclooxygenase gene
-
Kujubu DA and Herschman HR, Dexamethasone inhibits mitogen induction of the TIS 10 prostaglandin synthase cyclooxygenase gene. J Biol Chem 267: 7991-7994, 1992.
-
(1992)
J Biol Chem
, vol.267
, pp. 7991-7994
-
-
Kujubu, D.A.1
Herschman, H.R.2
-
25
-
-
0026548935
-
Endogenous glucocorticoids regulate inducible cyclooxygenase enzyme
-
Masferrer JL, Seibert K, Zweifel B and Needleman P, Endogenous glucocorticoids regulate inducible cyclooxygenase enzyme. Proc Natl Acad Sci USA 89: 3917-3921, 1992.
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 3917-3921
-
-
Masferrer, J.L.1
Seibert, K.2
Zweifel, B.3
Needleman, P.4
-
26
-
-
0025187588
-
Selective regulation of cellular cyclooxygenase by dexamethasone and endotoxin in mice
-
Masferrer JL, Zweifel BS, Seibert K and Needleman P, Selective regulation of cellular cyclooxygenase by dexamethasone and endotoxin in mice. J Clin Invest 86: 1375-1379, 1990.
-
(1990)
J Clin Invest
, vol.86
, pp. 1375-1379
-
-
Masferrer, J.L.1
Zweifel, B.S.2
Seibert, K.3
Needleman, P.4
-
27
-
-
0025185021
-
Inhibition of eicosanoid biosynthesis by glucocorticoids in humans
-
Sebaldt RJ, Shelter JR, Oates JA, Roberts LJ and Fitzgerald GA. Inhibition of eicosanoid biosynthesis by glucocorticoids in humans. Proc Natl Acad Sci USA 87: 6974-6978, 1990.
-
(1990)
Proc Natl Acad Sci USA
, vol.87
, pp. 6974-6978
-
-
Sebaldt, R.J.1
Shelter, J.R.2
Oates, J.A.3
Roberts, L.J.4
Fitzgerald, G.A.5
-
28
-
-
85029991266
-
The induction of a second and different cyclooxygenase is important in inflammation
-
(Ed. Vane JR), Sept. 28-29, London Abstr.
-
Vane JR, The induction of a second and different cyclooxygenase is important in inflammation. In: William Harvey Research Conference (Ed. Vane JR), Sept. 28-29, London 1992, Vol. 3, Abstr. p. 3.
-
(1992)
William Harvey Research Conference
, vol.3
, pp. 3
-
-
Vane, J.R.1
-
29
-
-
0028926813
-
New insights into the mode of action of anti-inflammatory drugs
-
Vane JR and Botting RM, New insights into the mode of action of anti-inflammatory drugs. Inflamm Res 44: 1-10, 1995.
-
(1995)
Inflamm Res
, vol.44
, pp. 1-10
-
-
Vane, J.R.1
Botting, R.M.2
-
30
-
-
0039119700
-
Some pharmacologic and biochemical aspects of prostaglandin biosynthesis and its inhibition
-
(Eds. Robinson HJ and Vane JR). Raven Press, New York
-
Flower RJ and Vane JR, Some pharmacologic and biochemical aspects of prostaglandin biosynthesis and its inhibition. In: Prostaglandin Synthetase Inhibitors (Eds. Robinson HJ and Vane JR), pp. 9-18. Raven Press, New York, 1974.
-
(1974)
Prostaglandin Synthetase Inhibitors
, pp. 9-18
-
-
Flower, R.J.1
Vane, J.R.2
-
31
-
-
13144274917
-
Zur pharmakologie der schwach wirksamen analgetika
-
(Ed. Forth W). Braun, Karlsruhe
-
Engelhardt G, Zur Pharmakologie der schwach wirksamen Analgetika. In: Zur Problematik der Schwach Wirksamen Analgetika (Ed. Forth W), pp. 100-108. Braun, Karlsruhe, 1986.
-
(1986)
Zur Problematik der Schwach Wirksamen Analgetika
, pp. 100-108
-
-
Engelhardt, G.1
-
32
-
-
0015511847
-
Inhibition of prostaglandin synthetase in brain explains the anti-pyretic activity of paracetamol (4-Acetamidophenol)
-
Flower R and Vane JR, Inhibition of prostaglandin synthetase in brain explains the anti-pyretic activity of paracetamol (4-Acetamidophenol). Nature 240: 410-411, 1972.
-
(1972)
Nature
, vol.240
, pp. 410-411
-
-
Flower, R.1
Vane, J.R.2
-
33
-
-
0027290813
-
Expression of a mitogen-inducible cyclooxygenase in brain neurons: Regulation by synaptic activity and glucocorticoids
-
Yamagata K, Andreasson KL, Kaufmann WE, Barbes CA and Worley PF, Expression of a mitogen-inducible cyclooxygenase in brain neurons: regulation by synaptic activity and glucocorticoids. Neuron 11: 371-386, 1993.
-
(1993)
Neuron
, vol.11
, pp. 371-386
-
-
Yamagata, K.1
Andreasson, K.L.2
Kaufmann, W.E.3
Barbes, C.A.4
Worley, P.F.5
-
34
-
-
0028984596
-
Expression of cyclooxygenase 2 in rat brain following kainate treatment
-
Chen Y, Marsh T, Zhang JS and Graham SH, Expression of cyclooxygenase 2 in rat brain following kainate treatment. Neuro Rep 6: 245-248, 1995.
-
(1995)
Neuro Rep
, vol.6
, pp. 245-248
-
-
Chen, Y.1
Marsh, T.2
Zhang, J.S.3
Graham, S.H.4
-
35
-
-
0028902109
-
Characterization of inducible cyclooxygenase in rat brain
-
Breder CD, DeWitt D and Kraig RP, Characterization of inducible cyclooxygenase in rat brain. J Comp Neurol 355: 196-215, 1995.
-
(1995)
J Comp Neurol
, vol.355
, pp. 196-215
-
-
Breder, C.D.1
DeWitt, D.2
Kraig, R.P.3
-
36
-
-
85029998519
-
Selective inhibition of the human PGH-synthase-1 and -2 (cyclooxygenase) isoenzymes by aspirin and other non-steroidal anti-inflammatory drugs
-
Abstract
-
De Witt DL, Lanenville O, Lecomte M, Hla T, Funk C and Smith M, Selective inhibition of the human PGH-synthase-1 and -2 (cyclooxygenase) isoenzymes by aspirin and other non-steroidal anti-inflammatory drugs. In: World Congress Inflammation '93, IAIS, Vienna, October 10-15, 1993, (Abstract) pp. 154.
-
World Congress Inflammation '93, IAIS, Vienna, October 10-15, 1993
, pp. 154
-
-
De Witt, D.L.1
Lanenville, O.2
Lecomte, M.3
Hla, T.4
Funk, C.5
Smith, M.6
-
37
-
-
85029999601
-
An anti-inflammatory agent, NS-398, selectively inhibits PGHS-2 activity in rat endotoxin shock
-
Abstract
-
Futaki N, Takahashi S, Yokoyama M, Arai J, Higuchi S and Otomo S, An anti-inflammatory agent, NS-398, selectively inhibits PGHS-2 activity in rat endotoxin shock. In: World Congress Inflammation '93, IAIS, Vienna, October 10-15, 1993, (Abstract) p. 52.
-
World Congress Inflammation '93, IAIS, Vienna, October 10-15, 1993
, pp. 52
-
-
Futaki, N.1
Takahashi, S.2
Yokoyama, M.3
Arai, J.4
Higuchi, S.5
Otomo, S.6
-
38
-
-
0040897814
-
Prostaglandin G/H synthase isozymes: A new target for drug discovery
-
Sircar JC, Prostaglandin G/H synthase isozymes: A new target for drug discovery. Curr Opin Invest Drugs 2: 403-407, 1993.
-
(1993)
Curr Opin Invest Drugs
, vol.2
, pp. 403-407
-
-
Sircar, J.C.1
|