V(D)J recombination frequency is affected by the sequence interposed between a pair of recombination signals: Sequence comparison reveals a putative recombinational enhancer element

Nucleic Acids Research

Volumn 25, Issue 12, 1997, Pages 2303-2310

  Roch, Florence A ^a,b   Hobi, Reinhard ^a   Berchtold, Martin W ^a,c   Kuenzle, Clive C ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

^b UNIVERSITY OF LAUSANNE   (Switzerland)

^c UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN HEAVY CHAIN;

ARTICLE; B LYMPHOCYTE; DNA FLANKING REGION; DNA RECOMBINATION; ENHANCER REGION; GENETIC TRANSFECTION; IMMUNOGLOBULIN GENE; INTRON; PLASMID; PRIORITY JOURNAL;

ANIMALS; ANTIBODY DIVERSITY; B-LYMPHOCYTES; BASE COMPOSITION; BASE SEQUENCE; CELL LINE; CONSENSUS SEQUENCE; ENHANCER ELEMENTS (GENETICS); GENE REARRANGEMENT, B-LYMPHOCYTE; HUMANS; IMMUNOGLOBULIN HEAVY CHAINS; IMMUNOGLOBULIN JOINING REGION; IMMUNOGLOBULIN VARIABLE REGION; INTRONS; MICE; MOLECULAR SEQUENCE DATA; PROTEIN SORTING SIGNALS; RECOMBINANT PROTEINS; RECOMBINATION, GENETIC; REGULATORY SEQUENCES, NUCLEIC ACID; TRANSCRIPTION, GENETIC; TRANSFECTION;

DROMAIUS NOVAEHOLLANDIAE; PROKARYOTA;

EID: 0030788616     PISSN: 03051048     EISSN: None     Source Type: Journal    
DOI: 10.1093/nar/25.12.2303     Document Type: Article

References (58)

1. Tonegawa,S. (1983) Nature, 302, 575-581.
2. Alt,F.W., Oltz,M., Young,F., Gorman,J., Taccioli,G. and Chen,J. (1992) Immunol. Today, 13, 306-314.
3. Schatz,D., Oettinger,M.A. and Schlissel,M.S. (1992) Annu. Rev. Immunol., 10, 359-383.
4. Roth,D.B., Menetski,J.P., Nakajima,P.B., Bosma,M.J. and Gellert,M. (1992) Cell, 70, 983-991.
5. Smider,V., Kimrin Rathmell,W., Lieber,M.R. and Chu,G. (1994) Science, 266, 288-291.
6. Taccioli,G.E., Gottlieb,T.M., Blunt,T., Priestly,A., Demengeot,J., Mizuta,R., Lehman,A.R., Alt,F.W., Jackson,S.P. and Jeggo,P.A. (1994) Science, 265, 1442-1445.
7. Boubnov,N.V., Hall,K.T., Wills,Z., Lee,S.E., He,D.M., Benjamin,D.M., Pulaski,C.R., Band,H., Reeves,W., Hendrickson,E.A. and Weaver,D.T. (1995) Proc. Natl. Acad. Sci. USA, 92, 890-894.
8. Blunt,T., Finnie,N.J., Taccioli,G.E., Smith,G.C.M., Demengeot,J., Gottlieb,T.M., Mizuta,R., Varghese,A.J., Alt,F.W., Jeggo,P.A. and Jackson,S.P. (1995) Cell, 80, 813-823.
9. Van Gent,D.C., McBlane,J.F., Ramsden,D.A., Sadowsky,M.J., Hesse,J.E. and Gellert,M. (1995) Cell, 81, 1-20.
10. Van Gent,D.C., Mizuuchi,K. and Gellert,M. (1996) Science, 271, 1592-1594.
11. Van Gent,D.C., Ramsden,D.A. and Gellert,M. (1996) Cell, 85, 107-113.
12. McBlane,J.F., van Gent,D.C., Ramsden,D.A., Romeo,C., Cuomo,C.A., Gellert,M. and Oettinger,M.A. (1995) Cell, 83, 387-396.
13. Eastman,Q.M., Leu,T.M.J. and Schatz,D.G. (1996) Nature, 380, 85-88.
14. Roman,C.A.J. and Baltimore,D. (1996) Proc. Natl. Acad. Sci. USA, 93, 2333-2338.
15. Difilippantonio,M.J., McMahan,C.J., Eastman,Q.M., Spanopoulou,E. and Schatz,D.G. (1996) Cell, 87, 253-262.
16. Spanopoulou,E., Zaitseva,F., Wang,F.-H., Santagata,S., Baltimore,D. and Panayotou,G. (1996) Cell, 87, 263-276.
17. Menetski,J.P. and Gellert,M. (1990) Proc. Natl. Acad. Sci. USA 87, 9324-9328.
18. Takahama,Y. and Singer,A. (1992) Science, 258, 1456-1462.
19. Neale,G.A.M., Fitzgerald,T.J. and Goorha,R.M. (1992) Mol. Immunol., 29, 1457-1466.
20. Takeda,S., Zou,Y.-R., Bluethmann,H., Kitamura,D., Muller,U. and Rajewsky,K. (1993) EMBO J., 12, 2329-2336.
21. Chen,J., Young,F., Bottaro,A., Stewart,V., Smith,R.K. and Alt,F.W. (1993) EMBO J., 12,4635-4645.
22. Serwe,M. and Sablitzky,F. (1993) EMBO J., 12, 2321-2327.
23. Oltz,E.M., Alt,F.W., Lin,W.-C. Chen,J., Taccioli,G., Desiderio,S. and Rathbun,G. (1993) Mol Cell. Biol., 13, 6223-6230.
24. Lin,W.-C. and Desiderio,S. (1993) Science, 260, 953-959.
25. Lin,W.-C. and Desiderio,S. (1994) Proc. Natl. Acad. Sci. USA, 91, 2733-2737.
26. Ferguson,S.E., Accavitti,M.A., Wang,D.D., Chen,C.-L. and Thompson,C.B. (1994) Mol. Cell. Biol., 14, 7298-7305.
27. Femex,C., Caillol,D., Capone,M., Krippl,B. and Ferrier,P. (1994) Nucleic Acids Res., 22, 792-798.
28. Fernex,C., Capone,M. and Ferrier,P. (1995) Mol. Cell. Biol., 15, 3217-3226.
29. Xu,Y., Davidson,L., Alt,F.W. and Baltimore,D. (1996) Immunity, 4, 377-385.
30. Döbbeling,U., Hobi,R., Berchtold,M.W. and Kuenzle,C.C. (1996) J. Mol. Biol., 261, 309-314.
31. Lauster,R., Reynaud,C.-A., Martensson,I.-L., Peter,A., Bucchini,D., Jami, J. and Weill,J.-C. (1993) EMBO J., 12, 4615-4623.
32. Capone,M., Watrin,F., Fernex,C., Horvat,B., Krippl,B., Wu,L., Scollay,R. and Ferner,P. (1993) EMBO J., 12, 4335-4346.
33. Bories,J.-C., Demengeot, J., Davidson,L. and Alt,F.W. (1996) Proc. Natl. Acad. Sci. USA, 93, 7871-7876.
34. Bouvier,G., Watrin,F., Naspetti,M., Verthuy,C., Naquet,P. and Ferrier,P. (1996) Proc. Natl. Acad. Sci. USA, 93, 7877-7881.
35. Kallenbach,S., Goodhart,M. and Rougeon,F. (1990) Nucleic Acids Res., 18, 6730.
36. Romig,H., Ruff,J., Fackelmayer,F.O., Patil,M.S. and Richter,A. (1994) Eur. J. Biochem., 221, 411-419.
37. Kunze,N., Klein,M., Richter,A. and Knippers,R. (1990) Eur. J. Biochem., 194, 323-330.
38. Stief,A., Winter,D.M., Strätling,W.H. and Sippel,A.E. (1989) Nature, 341, 343-345.
39. Phi-Van,L. and StrStling,W.H. (1988) EMBO J., 7, 655-664.
40. Gasser,S.M. and Laemmli,U.K. (1986) Cell, 46, 521-530.
41. Banerji,J., Olson,L. and Schaffner,W. (1983) Cell, 33, 729-740.
42. Cockerill,P.N., Yuen,M.-H. and Garrard,W.T. (1987) J. Biol. Chem., 262, 5394-5397.
43. Spitzner,J.R., Chung,J.K. and Muller,M.T. (1989) Nucleic Acids Res., 18, 1-11.
44. Alt,F.W., Rosenberg,S., Lewis,E.T. and Baltimore,D. (1981) Cell, 27, 381-390.
45. Leu,T.M.J. and Schatz,D.G. (1995) Mol. Cell. Biol. 15, 5657-5670.
46. Hesse,J.E., Lieber,M.R., Gellert,M. and Mizuuchi,K. (1987) Cell, 49, 775-783.
47. Sambrook,J., Fritsch,E.F. and Maniatis,T. (1989) Molecular Cloning: A Laboratory Manual, 2nd edition. Cold Spring Harbor Press, NY.
48. Inoue,H., Nojima,H. and Okayama,H. (1990) Gene, 96, 23-28.
49. Gerstein,R.M. and Lieber,M.R. (1993) Genes Dev., 7, 1459-1469.
50. Ferradini,L., Gu,H., De Smet,A., Rajewsky,K., Reynaud,C.-A. and Weill,J.-C. (1996) Science, 271, 1416-1420.
51. Staudt,L.M. and Lenardo,M.J. (1991) Annu. Rev. Immunol, 9, 373-398.
52. Romig,H., Fackelmayer,F.O., Renz,A., Ramsperger,U. and Richter,A. (1992) EMBO J., 11, 3431-3440.
53. Hesse,J.E., Lieber,M.R., Mizuuchi,K. and Gellert,M. (1989) Genes Dev., 3, 1053-1061.
54. Akamatsu,Y., Tsurushita,N., Nagawa,F., Matsuoka,M., Okazaki,K., Imai,M. and Sakano,H. (1994) J. Immunol., 153, 4520-4529.
55. Ramsden,D.A., McBlane,J.F., Van Gent,D.C. and Gellert,M. (1996) EMBO J., 15, 3197-3206.
56. Lieber,M.R., Hesse,J.E., Mizuuchi,K. and Gellert,M. (1987) Genes Dev., 1, 751-761.
57. Boubnov,N.V., Wills,Z.P. and Weaver,D.T. (1995) Nucleic Acids Res., 23, 1060-1067.
58. Ezekiel,U.R., Engler,P., Stern,D. and Storb,U. (1995) Immunity, 2, 381-389.