-
1
-
-
0028272242
-
Suppression of neointimal smooth muscle cell accumulation in vivo by antisense CDC2 and CDK2 oligonucleotides in rat carotid artery
-
Abe J., Zhou W., Taguchi J., et al. Suppression of neointimal smooth muscle cell accumulation in vivo by antisense CDC2 and CDK2 oligonucleotides in rat carotid artery. Biochem. Biophys. Res. Commun. 198 (1994) 16
-
(1994)
Biochem. Biophys. Res. Commun.
, vol.198
, pp. 16
-
-
Abe, J.1
Zhou, W.2
Taguchi, J.3
-
2
-
-
0028046810
-
In vivo treatment with antisense oligodeoxynucleotide to kappa-opioid receptors inhibited kappa-agonist-induced analgesia in rats.
-
Adams J.U., Chen X.H., de Riel J.K., et al. In vivo treatment with antisense oligodeoxynucleotide to kappa-opioid receptors inhibited kappa-agonist-induced analgesia in rats. Regul. Pept. 54 (1994) 1
-
(1994)
Regul. Pept.
, vol.54
, pp. 1
-
-
Adams, J.U.1
Chen, X.H.2
de Riel, J.K.3
-
3
-
-
0023755696
-
Oligodeoxynucleoside phosphoramidates and phosphorothioates as inhibitors of human immunodeficiency virus
-
Agrawal S., Goodchild J., Civeira M.P., et al. Oligodeoxynucleoside phosphoramidates and phosphorothioates as inhibitors of human immunodeficiency virus. Proc. Natl. Acad. Sci. U.S.A. 85 (1988) 7079
-
(1988)
Proc. Natl. Acad. Sci. U.S.A.
, vol.85
, pp. 7079
-
-
Agrawal, S.1
Goodchild, J.2
Civeira, M.P.3
-
4
-
-
0025743216
-
Pharmacokinetics, biodistribution and stability of oligodeoxynucleotide phosphorothioates in mice
-
Agrawal S., Temsamani J., and Tang J.Y. Pharmacokinetics, biodistribution and stability of oligodeoxynucleotide phosphorothioates in mice. Proc. Natl. Acad. Sci. U.S.A. 88 (1991) 7595
-
(1991)
Proc. Natl. Acad. Sci. U.S.A.
, vol.88
, pp. 7595
-
-
Agrawal, S.1
Temsamani, J.2
Tang, J.Y.3
-
5
-
-
0029100397
-
Absorption, tissue distribution and in vivo stability in rats of a hybrid antisense oligonucleotide following oral administration
-
Agrawal S., Zhang X., Lu Z., et al. Absorption, tissue distribution and in vivo stability in rats of a hybrid antisense oligonucleotide following oral administration. Biochem. Pharmacol. 50 (1995) 571
-
(1995)
Biochem. Pharmacol.
, vol.50
, pp. 571
-
-
Agrawal, S.1
Zhang, X.2
Lu, Z.3
-
6
-
-
0022972284
-
Inhibition of vesicular stomatitis virus protein synthesis and infection by sequence-specific oligodeoxyribonuclease methylphos-phonates
-
Agris C.H., Blake K.R., Miller P.S., et al. Inhibition of vesicular stomatitis virus protein synthesis and infection by sequence-specific oligodeoxyribonuclease methylphos-phonates. Biochemistry 25 (1986) 6268
-
(1986)
Biochemistry
, vol.25
, pp. 6268
-
-
Agris, C.H.1
Blake, K.R.2
Miller, P.S.3
-
7
-
-
0028157404
-
Specific inhibition of endogenous neuropeptide Y synthesis in arcuate nucleus by antisense oligonucleotides suppresses feeding behavior and insulin secretion
-
Akabayashi A., Wahlestedt C., Alexander J.T., et al. Specific inhibition of endogenous neuropeptide Y synthesis in arcuate nucleus by antisense oligonucleotides suppresses feeding behavior and insulin secretion. Mol. Brain Res. 21 (1994) 55
-
(1994)
Mol. Brain Res.
, vol.21
, pp. 55
-
-
Akabayashi, A.1
Wahlestedt, C.2
Alexander, J.T.3
-
8
-
-
0030031660
-
Antisense inhibition of parathyroid hormone-related peptide gene expression reduces malignant pituitary tumor progression and metastases in the rat
-
Akino K., Ohtsuru A., Yano H., et al. Antisense inhibition of parathyroid hormone-related peptide gene expression reduces malignant pituitary tumor progression and metastases in the rat. Cancer Res. 56 (1996) 77
-
(1996)
Cancer Res.
, vol.56
, pp. 77
-
-
Akino, K.1
Ohtsuru, A.2
Yano, H.3
-
10
-
-
0027267493
-
Inhibition of kinesin synthesis and rapid anterograde axonal transport in vivo by an antisense oligonucleotide
-
Amaratunga A., Morin P.J., Kosik K.S., et al. Inhibition of kinesin synthesis and rapid anterograde axonal transport in vivo by an antisense oligonucleotide. J. Biol. Chem. 268 (1993) 17427
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 17427
-
-
Amaratunga, A.1
Morin, P.J.2
Kosik, K.S.3
-
12
-
-
0027216834
-
Antiviral activity of a phosphorothioate oligonucleotide complementary to RNA of the human cytomegalovirus major immediate-early region
-
Azad R.F., Driver V.B., Tanaka K., et al. Antiviral activity of a phosphorothioate oligonucleotide complementary to RNA of the human cytomegalovirus major immediate-early region. Antimicrob. Agents Chemothe. 37 (1993) 1945
-
(1993)
Antimicrob. Agents Chemothe.
, vol.37
, pp. 1945
-
-
Azad, R.F.1
Driver, V.B.2
Tanaka, K.3
-
13
-
-
0000938504
-
Decapitation of a 5 capped oligoribonucleotide by ortho-phenanthroline:Cu(II).
-
Baker B. Decapitation of a 5 capped oligoribonucleotide by ortho-phenanthroline:Cu(II). J. Am. Chem. Soc. 115 (1993) 3378
-
(1993)
J. Am. Chem. Soc.
, vol.115
, pp. 3378
-
-
Baker, B.1
-
14
-
-
0026648540
-
Modulation of eukaryotic initiation factor-4E binding to 5′ capped oligoribonucleotides by modified antisense oligonucleotides
-
Baker B.F., Miraglia L., and Hagedorn C.H. Modulation of eukaryotic initiation factor-4E binding to 5′ capped oligoribonucleotides by modified antisense oligonucleotides. J. Biol. Chem. 267 (1992) 11495
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 11495
-
-
Baker, B.F.1
Miraglia, L.2
Hagedorn, C.H.3
-
15
-
-
0016176432
-
Inhibitory effect of a complex formation with oligodeoxyribonucleotide ethyl phosphotriesters on transfer ribonucleic acid aminoacylation
-
Barrett J.C., Miller P.S., and Ts'o P.O.P. Inhibitory effect of a complex formation with oligodeoxyribonucleotide ethyl phosphotriesters on transfer ribonucleic acid aminoacylation. Biochemistry 13 (1974) 4897
-
(1974)
Biochemistry
, vol.13
, pp. 4897
-
-
Barrett, J.C.1
Miller, P.S.2
Ts'o, P.O.P.3
-
16
-
-
0028953137
-
Antisense oligonucleotides directed against p53 have antiproliferative effects unrelated to effects on p53 expression
-
Barton C.M., and Lemoine N.R. Antisense oligonucleotides directed against p53 have antiproliferative effects unrelated to effects on p53 expression. Br. J. Cancer 71 (1995) 429
-
(1995)
Br. J. Cancer
, vol.71
, pp. 429
-
-
Barton, C.M.1
Lemoine, N.R.2
-
17
-
-
0027729703
-
Systemic administration of a phosphorothioate oligonucleotide with a sequence complementary to p53 for acute myelogenous leukemia and myelodysplastic syndrome: Initial results of a phase 1 trial
-
Bayever E., Iversen P.L., Bishop M.R., et al. Systemic administration of a phosphorothioate oligonucleotide with a sequence complementary to p53 for acute myelogenous leukemia and myelodysplastic syndrome: Initial results of a phase 1 trial. Antisense Res. Dev. 3 (1993) 383
-
(1993)
Antisense Res. Dev.
, vol.3
, pp. 383
-
-
Bayever, E.1
Iversen, P.L.2
Bishop, M.R.3
-
18
-
-
0042798373
-
4-Thio RNA: A novel class of sugar-modified β-RNA
-
Sanghvi Y.S., and Cook P.D. (Eds), American Chemical Society, Washington, D.C.
-
Bellon L., Leydier C., Barascut J.-L., et al. 4-Thio RNA: A novel class of sugar-modified β-RNA. In: Sanghvi Y.S., and Cook P.D. (Eds). Carbohydrate Modifications in Antisense Research (1994), American Chemical Society, Washington, D.C. 68
-
(1994)
Carbohydrate Modifications in Antisense Research
, pp. 68
-
-
Bellon, L.1
Leydier, C.2
Barascut, J.-L.3
-
19
-
-
0001274077
-
Oligonucleotide-based inhibitors of cytokine expression and function
-
Henderson B., and Bodmer M.W. (Eds), CRC Press, Boca Raton, Florida.
-
Bennett C.F., and Crooke S.T. Oligonucleotide-based inhibitors of cytokine expression and function. In: Henderson B., and Bodmer M.W. (Eds). "Therapeutic Modulation of Cytokines," a volume in "Pharmacology and Toxicology: Basic and Clinical Aspects (1996), CRC Press, Boca Raton, Florida. 171-193
-
(1996)
"Therapeutic Modulation of Cytokines," a volume in "Pharmacology and Toxicology: Basic and Clinical Aspects
, pp. 171-193
-
-
Bennett, C.F.1
Crooke, S.T.2
-
20
-
-
0027092897
-
Cationic lipids enhance cellular uptake and activity of phosphorothioate antisense oligonucleotides
-
Bennett C.F., Chiang M.-Y., Chan H., et al. Cationic lipids enhance cellular uptake and activity of phosphorothioate antisense oligonucleotides. Mol. Pharmacol. 41 (1992) 1023
-
(1992)
Mol. Pharmacol.
, vol.41
, pp. 1023
-
-
Bennett, C.F.1
Chiang, M.-Y.2
Chan, H.3
-
21
-
-
0027513750
-
Use of cationic lipids to enhance the biological activity of antisense oligonucleotides
-
Bennett C.F., Chiang M.-Y., Chan H., et al. Use of cationic lipids to enhance the biological activity of antisense oligonucleotides. J. Liposome Res. 3 (1993) 85
-
(1993)
J. Liposome Res.
, vol.3
, pp. 85
-
-
Bennett, C.F.1
Chiang, M.-Y.2
Chan, H.3
-
22
-
-
85024003311
-
Cell penetration studies of oligonucleotides derivatized with cholesterol and porphyrins
-
(abstr.)
-
Boutorine A., Huet C., Saison T., et al. Cell penetration studies of oligonucleotides derivatized with cholesterol and porphyrins. Conf. Nucleic Acid Ther. (1991) 60 (abstr.)
-
(1991)
Conf. Nucleic Acid Ther.
, pp. 60
-
-
Boutorine, A.1
Huet, C.2
Saison, T.3
-
24
-
-
0026012338
-
Oligonucleotides antisense to the interleukin 1 receptor mRNA block the effects of interleukin 1 in cultured murine and human fibroblasts and in mice
-
Burch R.M., and Mahan L.C. Oligonucleotides antisense to the interleukin 1 receptor mRNA block the effects of interleukin 1 in cultured murine and human fibroblasts and in mice. J. Clin. Invest. 88 (1991) 1190
-
(1991)
J. Clin. Invest.
, vol.88
, pp. 1190
-
-
Burch, R.M.1
Mahan, L.C.2
-
25
-
-
0029001621
-
The antiproliferative activity of c-myb and c-myc antisense oligonucleotides in smooth muscle cells is caused by a nonantisense mechanism
-
Burgess T.L., Fisher E.F., Ross S.L., et al. The antiproliferative activity of c-myb and c-myc antisense oligonucleotides in smooth muscle cells is caused by a nonantisense mechanism. Proc. Natl. Acad. Sci. U.S.A. 92 (1995) 4051
-
(1995)
Proc. Natl. Acad. Sci. U.S.A.
, vol.92
, pp. 4051
-
-
Burgess, T.L.1
Fisher, E.F.2
Ross, S.L.3
-
26
-
-
0025346998
-
Oligodeoxynucleoside phosphorothioate stability in subcellular extracts, culture media, sera and cerebrospinal fluid
-
Campbell J.M., Bacon T.A., and Wickström E. Oligodeoxynucleoside phosphorothioate stability in subcellular extracts, culture media, sera and cerebrospinal fluid. J. Biochem. Biophys. Methods 20 (1990) 259
-
(1990)
J. Biochem. Biophys. Methods
, vol.20
, pp. 259
-
-
Campbell, J.M.1
Bacon, T.A.2
Wickström, E.3
-
27
-
-
0022144562
-
Gene synthesis machines: DNA chemistry and its uses
-
Caruthers M.H. Gene synthesis machines: DNA chemistry and its uses. Science 230 (1985) 281
-
(1985)
Science
, vol.230
, pp. 281
-
-
Caruthers, M.H.1
-
28
-
-
0027937816
-
Learning of the conditioned eye-blink response is impaired by an antisense insulin-like growth factor I oligonucleotide
-
Castro-Alamancos M.A., and Torres-Aleman I. Learning of the conditioned eye-blink response is impaired by an antisense insulin-like growth factor I oligonucleotide. Proc. Natl. Acad. Sci. U.S.A. 91 (1994) 10203
-
(1994)
Proc. Natl. Acad. Sci. U.S.A.
, vol.91
, pp. 10203
-
-
Castro-Alamancos, M.A.1
Torres-Aleman, I.2
-
29
-
-
0024407164
-
Comparative inhibition of rabbit globin mRNA translation by modified antisense oligodeoxynucleotides
-
Cazenave C., Stein C.A., Loreau N., et al. Comparative inhibition of rabbit globin mRNA translation by modified antisense oligodeoxynucleotides. Nucleic Acids Res. 17 (1989) 4255
-
(1989)
Nucleic Acids Res.
, vol.17
, pp. 4255
-
-
Cazenave, C.1
Stein, C.A.2
Loreau, N.3
-
30
-
-
0028828438
-
Opioid peptide receptor studies. 4. Antisense oligodeoxynucleotide to the δ-opiod receptor delineates opiod receptor subtypes
-
Cha X.Y., Xu H., Ni Q., et al. Opioid peptide receptor studies. 4. Antisense oligodeoxynucleotide to the δ-opiod receptor delineates opiod receptor subtypes. Regul. Pept. 59 (1995) 247
-
(1995)
Regul. Pept.
, vol.59
, pp. 247
-
-
Cha, X.Y.1
Xu, H.2
Ni, Q.3
-
31
-
-
0026334812
-
Against human immunodeficiency virus and herpes viruses
-
Cheng Y.-C., Gao W., and Han F. Against human immunodeficiency virus and herpes viruses. Nucleosides Nucleotides 10 (1991) 155
-
(1991)
Nucleosides Nucleotides
, vol.10
, pp. 155
-
-
Cheng, Y.-C.1
Gao, W.2
Han, F.3
-
32
-
-
0026052924
-
Antisense oligonucleotides inhibit ICAM-1 expression by two distinct mechanisms
-
Chiang M.Y., Chan H., Zounes M.A., et al. Antisense oligonucleotides inhibit ICAM-1 expression by two distinct mechanisms. J. Biol. Chem. 266 (1991) 18162
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 18162
-
-
Chiang, M.Y.1
Chan, H.2
Zounes, M.A.3
-
33
-
-
0026497249
-
Antisense oligonucleotide eliminates in vivo expression of c-fos in mammalian brain
-
Chiasson B.J., Hooper M.L., Murphy P.R., et al. Antisense oligonucleotide eliminates in vivo expression of c-fos in mammalian brain. Eur. J. Pharmacol. 227 (1992) 451
-
(1992)
Eur. J. Pharmacol.
, vol.227
, pp. 451
-
-
Chiasson, B.J.1
Hooper, M.L.2
Murphy, P.R.3
-
34
-
-
0027760969
-
Internalization of oligodeoxyribonucleotides by Vibrio parahaemolyticus.
-
Chrissey L.A., Walz S.E., Pazirandeh M., et al. Internalization of oligodeoxyribonucleotides by Vibrio parahaemolyticus. Antisense Res. Dev. 3 (1993) 367
-
(1993)
Antisense Res. Dev.
, vol.3
, pp. 367
-
-
Chrissey, L.A.1
Walz, S.E.2
Pazirandeh, M.3
-
35
-
-
0003126130
-
Phosphorothioate oligodeoxynucleotides
-
Crooke S.T., and Lebleu B. (Eds), CRC Press, Boca Raton, Florida.
-
Cohen J.S. Phosphorothioate oligodeoxynucleotides. In: Crooke S.T., and Lebleu B. (Eds). Antisense Research and Applications (1993), CRC Press, Boca Raton, Florida. 205
-
(1993)
Antisense Research and Applications
, pp. 205
-
-
Cohen, J.S.1
-
36
-
-
0015182075
-
The induction of interferon by natural and synthetic polynucleotides
-
Colby C. The induction of interferon by natural and synthetic polynucleotides. Prog. Nucleic Acid Res. Mol. Biol. 11 (1971) 1
-
(1971)
Prog. Nucleic Acid Res. Mol. Biol.
, vol.11
, pp. 1
-
-
Colby, C.1
-
37
-
-
0003098462
-
Medicinal chemistry strategies for antisense research
-
Crooke S.T., and Lebleu B. (Eds), CRC Press, Boca Raton, Florida.
-
Cook P.D. Medicinal chemistry strategies for antisense research. In: Crooke S.T., and Lebleu B. (Eds). Antisense Research and Applications (1993), CRC Press, Boca Raton, Florida. 303
-
(1993)
Antisense Research and Applications
, pp. 303
-
-
Cook, P.D.1
-
38
-
-
0027182233
-
Cardiovascular effects of a phosphorothioate oligonucleotide with sequence antisense to p53 in the conscious rhesus monkey
-
Cornish K.G., Iversen P., Smith L., et al. Cardiovascular effects of a phosphorothioate oligonucleotide with sequence antisense to p53 in the conscious rhesus monkey. Pharmacol. Commun. 3 (1993) 239
-
(1993)
Pharmacol. Commun.
, vol.3
, pp. 239
-
-
Cornish, K.G.1
Iversen, P.2
Smith, L.3
-
39
-
-
0027786912
-
14C-labeled phosphorothioate oligonucleotide ISIS 2105 after intravenous administration to rats
-
14C-labeled phosphorothioate oligonucleotide ISIS 2105 after intravenous administration to rats. J. Pharmacol. Exp. Ther. 267 (1993) 1181
-
(1993)
J. Pharmacol. Exp. Ther.
, vol.267
, pp. 1181
-
-
Cossum, P.A.1
Sasmor, H.2
Dellinger, D.3
-
40
-
-
0028183175
-
14C labeled phosphorothioate oligonucleotide, ISIS 2105, after intradermal administration to rats
-
14C labeled phosphorothioate oligonucleotide, ISIS 2105, after intradermal administration to rats. J. Pharmacol. Exp. Ther. 269 (1994) 89
-
(1994)
J. Pharmacol. Exp. Ther.
, vol.269
, pp. 89
-
-
Cossum, P.A.1
Truong, L.2
Owens, S.R.3
-
41
-
-
0011185924
-
Antiviral activities of oligonucleotides
-
Crooke S.T., and Lebleu B. (Eds), CRC Press, Boca Raton, Florida.
-
Cowsert L.M. Antiviral activities of oligonucleotides. In: Crooke S.T., and Lebleu B. (Eds). Antisense Research and Applications (1993), CRC Press, Boca Raton, Florida. 521
-
(1993)
Antisense Research and Applications
, pp. 521
-
-
Cowsert, L.M.1
-
43
-
-
0026356572
-
In vitro toxicology and pharmacokinetics of antisense oligonucleotides.
-
Crooke R.M. In vitro toxicology and pharmacokinetics of antisense oligonucleotides. Anti-Cancer Drug Des. 6 (1991) 609
-
(1991)
Anti-Cancer Drug Des.
, vol.6
, pp. 609
-
-
Crooke, R.M.1
-
44
-
-
0002442281
-
Cellular uptake, distribution and metabolism of phosphorothioate, phosphorodiester and methylphosphonate oligonucleotides
-
Crooke S.T., and Lebleu B. (Eds), CRC Press, Boca Raton, Florida.
-
Crooke R.M. Cellular uptake, distribution and metabolism of phosphorothioate, phosphorodiester and methylphosphonate oligonucleotides. In: Crooke S.T., and Lebleu B. (Eds). Antisense Research and Applications (1993), CRC Press, Boca Raton, Florida. 427
-
(1993)
Antisense Research and Applications
, pp. 427
-
-
Crooke, R.M.1
-
45
-
-
0002442281
-
In vitro and in vivo toxicology of first generation analogs
-
Crooke S.T., and Lebleu B. (Eds), CRC Press, Boca Raton, Florida.
-
Crooke R.M. In vitro and in vivo toxicology of first generation analogs. In: Crooke S.T., and Lebleu B. (Eds). Antisense Research and Applications (1993), CRC Press, Boca Raton, Florida. 471
-
(1993)
Antisense Research and Applications
, pp. 471
-
-
Crooke, R.M.1
-
46
-
-
0028856820
-
In vitro pharmacokinetics of phosphorothioate antisense oligonucleotides.
-
Crooke R.M., Graham M.J., Cooke M.E., et al. In vitro pharmacokinetics of phosphorothioate antisense oligonucleotides. J. Pharmacol. Toxicol. 275 (1995) 462
-
(1995)
J. Pharmacol. Toxicol.
, vol.275
, pp. 462
-
-
Crooke, R.M.1
Graham, M.J.2
Cooke, M.E.3
-
47
-
-
0030245626
-
Effect of antisense oligonucleotides on cytokine release from human keratinocytes in an in vitro model of skin
-
Crooke R.M., Crooke S.T., Graham M.J., et al. Effect of antisense oligonucleotides on cytokine release from human keratinocytes in an in vitro model of skin. Toxicol. Appl. Pharmacol. 140 (1996) 85-93
-
(1996)
Toxicol. Appl. Pharmacol.
, vol.140
, pp. 85-93
-
-
Crooke, R.M.1
Crooke, S.T.2
Graham, M.J.3
-
48
-
-
0026721173
-
Therapeutic applications of oligonucleotides
-
Crooke S.T. Therapeutic applications of oligonucleotides. Annu. Rev. Pharmacol. Toxicol. 32 (1992) 329
-
(1992)
Annu. Rev. Pharmacol. Toxicol.
, vol.32
, pp. 329
-
-
Crooke, S.T.1
-
49
-
-
0027481659
-
Progress toward oligonucleotide therapeutics: Pharmacodynamic properties
-
Crooke S.T. Progress toward oligonucleotide therapeutics: Pharmacodynamic properties. FASEB J. 7 (1993) 533
-
(1993)
FASEB J.
, vol.7
, pp. 533
-
-
Crooke, S.T.1
-
52
-
-
0004244327
-
-
Crooke S.T., and Lebleu B. (Eds), CRC Press, Boca Raton, Florida.
-
In: Crooke S.T., and Lebleu B. (Eds). "Antisense Research and Applications." (1993), CRC Press, Boca Raton, Florida.
-
(1993)
"Antisense Research and Applications."
-
-
-
54
-
-
0029619816
-
Kinetic characteristics of E. coli RNase H1: Cleavage of various antisense oligonucleotide-RNA duplexes
-
Crooke S.T., Lemonidis K.M., Neilson L., et al. Kinetic characteristics of E. coli RNase H1: Cleavage of various antisense oligonucleotide-RNA duplexes. Biochem. J. 312 (1995) 599
-
(1995)
Biochem. J.
, vol.312
, pp. 599
-
-
Crooke, S.T.1
Lemonidis, K.M.2
Neilson, L.3
-
55
-
-
12644302203
-
Pharmacokinetic properties of several novel oligonucleotide analogs in mice.
-
Crooke S.T., Graham M.J., Zuckerman J.E., et al. Pharmacokinetic properties of several novel oligonucleotide analogs in mice. J. Pharmacol. Exp. Ther. 277 2 (1996) 923-937
-
(1996)
J. Pharmacol. Exp. Ther.
, vol.277
, Issue.2
, pp. 923-937
-
-
Crooke, S.T.1
Graham, M.J.2
Zuckerman, J.E.3
-
56
-
-
0001711937
-
Ribonucleases H
-
Linn S.M., and Roberts R.J. (Eds), Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York.
-
Crouch R.J., and Dirksen M.-L. Ribonucleases H. In: Linn S.M., and Roberts R.J. (Eds). Nucleases (1985), Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York. 211
-
(1985)
Nucleases
, pp. 211
-
-
Crouch, R.J.1
Dirksen, M.-L.2
-
57
-
-
0024296810
-
Complementary oligodeoxynucleotide mediated inhibition of tobacco mosaic virus RNA translation in vitro.
-
Crum C., Johnson J.D., Nelson A., et al. Complementary oligodeoxynucleotide mediated inhibition of tobacco mosaic virus RNA translation in vitro. Nucleic Acid Res. 16 (1988) 4569
-
(1988)
Nucleic Acid Res.
, vol.16
, pp. 4569
-
-
Crum, C.1
Johnson, J.D.2
Nelson, A.3
-
58
-
-
0028062847
-
Inhibition of PKC-α expression in mice after systemic administration of phosphorothioate antisense oligonucleotides
-
Dean N.M., and McKay R. Inhibition of PKC-α expression in mice after systemic administration of phosphorothioate antisense oligonucleotides. Proc. Natl. Acad. Sci. U.S.A. 91 (1994) 11762
-
(1994)
Proc. Natl. Acad. Sci. U.S.A.
, vol.91
, pp. 11762
-
-
Dean, N.M.1
McKay, R.2
-
59
-
-
8944231156
-
Inhibition of growth of human tumor cell lines in nude mice by an antisense oligonucleotide inhibitor of PKC-α expression
-
Dean N.M., McKay R., Miraglia L., et al. Inhibition of growth of human tumor cell lines in nude mice by an antisense oligonucleotide inhibitor of PKC-α expression. Cancer Res. 56 (1996) 3499-3507
-
(1996)
Cancer Res.
, vol.56
, pp. 3499-3507
-
-
Dean, N.M.1
McKay, R.2
Miraglia, L.3
-
60
-
-
0014672877
-
Interferon induction increased through chemical modification of a synthetic polyribonucleotide.
-
DeClercq E., Eckstein F., and Merigan T.C. Interferon induction increased through chemical modification of a synthetic polyribonucleotide. Science 165 (1969) 1137
-
(1969)
Science
, vol.165
, pp. 1137
-
-
DeClercq, E.1
Eckstein, F.2
Merigan, T.C.3
-
62
-
-
0028910689
-
Cholesteryl-conjugated phosphorothioate oligodeoxynucleotides modulate CYP2B1 expression in vivo.
-
Desjardins J., Mata J., Brown T., et al. Cholesteryl-conjugated phosphorothioate oligodeoxynucleotides modulate CYP2B1 expression in vivo. J. Drug Target. 2 (1995) 477
-
(1995)
J. Drug Target.
, vol.2
, pp. 477
-
-
Desjardins, J.1
Mata, J.2
Brown, T.3
-
63
-
-
0027284424
-
Restoration of correct splicing in thalassemic pre-mRNA by antisense oligonucleotides
-
Dominski Z., and Kole R. Restoration of correct splicing in thalassemic pre-mRNA by antisense oligonucleotides. Proc. Natl. Acad. Sci. U.S.A. 90 (1993) 673
-
(1993)
Proc. Natl. Acad. Sci. U.S.A.
, vol.90
, pp. 673
-
-
Dominski, Z.1
Kole, R.2
-
64
-
-
0018788204
-
Site specific enzymatic cleavage of RNA
-
Doris-Keller H. Site specific enzymatic cleavage of RNA. Nucleic Acids Res. 7 (1979) 179
-
(1979)
Nucleic Acids Res.
, vol.7
, pp. 179
-
-
Doris-Keller, H.1
-
65
-
-
0011927936
-
Strategies for invasion of RNA secondary structure
-
Crooke S.T., and Lebleu B. (Eds), CRC Press, Boca Raton, Florida.
-
Ecker D.J. Strategies for invasion of RNA secondary structure. In: Crooke S.T., and Lebleu B. (Eds). Antisense Research and Applications (1993), CRC Press, Boca Raton, Florida. 387
-
(1993)
Antisense Research and Applications
, pp. 387
-
-
Ecker, D.J.1
-
67
-
-
0025911370
-
Ribonuclease H from K562 human erythroleukemia cells
-
Eder P.S., and Walder J.A. Ribonuclease H from K562 human erythroleukemia cells. J. Biol. Chem. 206 (1991) 6472
-
(1991)
J. Biol. Chem.
, vol.206
, pp. 6472
-
-
Eder, P.S.1
Walder, J.A.2
-
68
-
-
0027295993
-
Arginine vasopressin levels after daily infusions of antisense oligonucleotides into the supraoptic nucleus
-
Flanagan L.M., McCarthy M.M., Brooks P.J., Pfaff D.W., and McEwen B.S. Arginine vasopressin levels after daily infusions of antisense oligonucleotides into the supraoptic nucleus. Ann. N. Y. Acad. Sci. 689 (1993) 520
-
(1993)
Ann. N. Y. Acad. Sci.
, vol.689
, pp. 520
-
-
Flanagan, L.M.1
McCarthy, M.M.2
Brooks, P.J.3
Pfaff, D.W.4
McEwen, B.S.5
-
69
-
-
0002326455
-
Hybridization: Considerations affecting antisense drugs
-
Crooke S.T., and Lebleu B. (Eds), CRC Press, Boca Raton, Florida.
-
Freier S.M. Hybridization: Considerations affecting antisense drugs. In: Crooke S.T., and Lebleu B. (Eds). Antisense Research and Applications (1993), CRC Press, Boca Raton, Florida. 67
-
(1993)
Antisense Research and Applications
, pp. 67
-
-
Freier, S.M.1
-
70
-
-
0024326585
-
RNase H cleavage of RNA hybridized to oligonucleotides containing methylphosphonate, phosphorothioate and phosphodiester bonds
-
Furdon P., Dominski Z., and Kole R. RNase H cleavage of RNA hybridized to oligonucleotides containing methylphosphonate, phosphorothioate and phosphodiester bonds. Nucleic Acids Res. 17 (1989) 9193
-
(1989)
Nucleic Acids Res.
, vol.17
, pp. 9193
-
-
Furdon, P.1
Dominski, Z.2
Kole, R.3
-
71
-
-
0023573266
-
α-DNA. VI: Comparative study of α-and β-anomeric oligodeoxyribonucleotides in hybridization to mRNA and in cell free translation inhibition
-
Gagnor C., Bertrand J., Thenet S., et al. α-DNA. VI: Comparative study of α-and β-anomeric oligodeoxyribonucleotides in hybridization to mRNA and in cell free translation inhibition. Nucleic Acids Res. 15 (1987) 10419
-
(1987)
Nucleic Acids Res.
, vol.15
, pp. 10419
-
-
Gagnor, C.1
Bertrand, J.2
Thenet, S.3
-
72
-
-
0024412596
-
α-DNA. IX. Parallel annealing of α-anomeric oligodeoxyribonucleotides to natural mRNA is required for interference in RNase H mediated hydrolysis and reverse transcription
-
Gagnor C., Rayner B., Leonetti J.-P., et al. α-DNA. IX. Parallel annealing of α-anomeric oligodeoxyribonucleotides to natural mRNA is required for interference in RNase H mediated hydrolysis and reverse transcription. Nucleic Acids Res. 17 (1989) 5107
-
(1989)
Nucleic Acids Res.
, vol.17
, pp. 5107
-
-
Gagnor, C.1
Rayner, B.2
Leonetti, J.-P.3
-
73
-
-
0028596461
-
Complement activation and hemodynamic changes following intravenous administration of phosphorothioate oligonucleotides in the monkey
-
Galbraith W.M., Hobson W.C., Giclas P.C., et al. Complement activation and hemodynamic changes following intravenous administration of phosphorothioate oligonucleotides in the monkey. Antisense Res. Dev. 4 (1994) 201
-
(1994)
Antisense Res. Dev.
, vol.4
, pp. 201
-
-
Galbraith, W.M.1
Hobson, W.C.2
Giclas, P.C.3
-
74
-
-
0024411480
-
Effect of phosphorothioate homooligodeoxynucleotides on herpes simplex virus type 2-induced DNA polymerase
-
Gao W., Stein C.A., Cohen J.S., et al. Effect of phosphorothioate homooligodeoxynucleotides on herpes simplex virus type 2-induced DNA polymerase. J. Biol. Chem. 264 (1989) 11521
-
(1989)
J. Biol. Chem.
, vol.264
, pp. 11521
-
-
Gao, W.1
Stein, C.A.2
Cohen, J.S.3
-
75
-
-
0026573769
-
Phosphorothioate oligonucleotides are inhibitors of human DNA polymerases and RNase H: Implications for antisense technology
-
Gao W.-Y., Han F.-S., Storm C., et al. Phosphorothioate oligonucleotides are inhibitors of human DNA polymerases and RNase H: Implications for antisense technology. Mol. Pharmacol. 41 (1991) 223
-
(1991)
Mol. Pharmacol.
, vol.41
, pp. 223
-
-
Gao, W.-Y.1
Han, F.-S.2
Storm, C.3
-
76
-
-
0026588983
-
Increased specificity for antisense oligodeoxynucleotide targeting of RNA cleavage of RNase H using chimeric methylphosphorodiester structures
-
Giles R.V., and Tidd D.M. Increased specificity for antisense oligodeoxynucleotide targeting of RNA cleavage of RNase H using chimeric methylphosphorodiester structures. Nucleic Acids Res. 20 (1992) 763
-
(1992)
Nucleic Acids Res.
, vol.20
, pp. 763
-
-
Giles, R.V.1
Tidd, D.M.2
-
77
-
-
0029089239
-
Detection of ribonuclease H-generated mRNA fragments in human leukemia cells following reversible membrane permeabilization in the presence of antisense oligodeoxynucleotides
-
Giles R.V., Spiller D.G., and Tidd D.M. Detection of ribonuclease H-generated mRNA fragments in human leukemia cells following reversible membrane permeabilization in the presence of antisense oligodeoxynucleotides. Antisense Res. Dev. 5 (1995) 23
-
(1995)
Antisense Res. Dev.
, vol.5
, pp. 23
-
-
Giles, R.V.1
Spiller, D.G.2
Tidd, D.M.3
-
78
-
-
0028181829
-
Inhibition of c-fos protein expression in rat spinal cord by antisense oligodeoxynucleotide superfusion
-
Gillardon F., Beck H., Uhlmann E., et al. Inhibition of c-fos protein expression in rat spinal cord by antisense oligodeoxynucleotide superfusion. Eur. J. Neurosci. 6 (1994) 880
-
(1994)
Eur. J. Neurosci.
, vol.6
, pp. 880
-
-
Gillardon, F.1
Beck, H.2
Uhlmann, E.3
-
79
-
-
0013786552
-
A quantitative assay for DNA-RNA hybrids with DNA immobilized on a membrane
-
Gillespie D., and Spiegelman S. A quantitative assay for DNA-RNA hybrids with DNA immobilized on a membrane. J. Mol. Biol. 12 (1965) 829-842
-
(1965)
J. Mol. Biol.
, vol.12
, pp. 829-842
-
-
Gillespie, D.1
Spiegelman, S.2
-
80
-
-
0030987678
-
Phase I safety and pharmacokinetic profile of an ICAM-1 antisense oligonucleotide (ISIS 2302)
-
In press.
-
Glover J.M., Leeds J.M., and Mant T.G.K. Phase I safety and pharmacokinetic profile of an ICAM-1 antisense oligonucleotide (ISIS 2302). J. Pharmacol. Exp. Ther. (1997) In press.
-
(1997)
J. Pharmacol. Exp. Ther.
-
-
Glover, J.M.1
Leeds, J.M.2
Mant, T.G.K.3
-
81
-
-
0003799787
-
Inhibition of human immunodeficiency virus replication by antisense oligonucleotides
-
Goodchild J., Agrawal S., Civeira M.P., et al. Inhibition of human immunodeficiency virus replication by antisense oligonucleotides. Proc. Natl. Acad. Sci. U.S.A. 85 (1988) 5507
-
(1988)
Proc. Natl. Acad. Sci. U.S.A.
, vol.85
, pp. 5507
-
-
Goodchild, J.1
Agrawal, S.2
Civeira, M.P.3
-
82
-
-
0027279436
-
Tritium labeling of antisense oligonucleotides by exchange with tritiated water
-
Graham M.J., Freier S.M., Crooke R.M., et al. Tritium labeling of antisense oligonucleotides by exchange with tritiated water. Nucleic Acids Res. 21 (1993) 3737
-
(1993)
Nucleic Acids Res.
, vol.21
, pp. 3737
-
-
Graham, M.J.1
Freier, S.M.2
Crooke, R.M.3
-
83
-
-
0028124707
-
5-Heteroaryl-2-deoxyuridine analogs. Synthesis and incorporation into high-affinity oligonucleotides
-
Gutierrez A.J., Terhorst T.J., Matteucci M.D., et al. 5-Heteroaryl-2-deoxyuridine analogs. Synthesis and incorporation into high-affinity oligonucleotides. J. Am. Chem. Soc. 116 (1994) 5540
-
(1994)
J. Am. Chem. Soc.
, vol.116
, pp. 5540
-
-
Gutierrez, A.J.1
Terhorst, T.J.2
Matteucci, M.D.3
-
84
-
-
0027333008
-
1 receptor mRNA and angiotensinogen mRNA in the brain of spontaneously hypertensive rats reduces hypertension of neurogenic origin
-
1 receptor mRNA and angiotensinogen mRNA in the brain of spontaneously hypertensive rats reduces hypertension of neurogenic origin. Regul. Pept. 49 (1993) 167
-
(1993)
Regul. Pept.
, vol.49
, pp. 167
-
-
Gyurko, F.1
Wielbo, D.2
Phillips, M.I.3
-
85
-
-
0023046569
-
Translation arrest by oligodeoxynucleotides complementary to mRNA coding sequences yields polypeptides of predetermined length
-
Haeuptle M.T., Frank R., and Dobberstein B. Translation arrest by oligodeoxynucleotides complementary to mRNA coding sequences yields polypeptides of predetermined length. Nucleic Acids Res. 14 (1986) 1427
-
(1986)
Nucleic Acids Res.
, vol.14
, pp. 1427
-
-
Haeuptle, M.T.1
Frank, R.2
Dobberstein, B.3
-
87
-
-
0028533862
-
Efficient sequence-specific cleavage of RNA using novel europium complexes conjugated to oligonucleotides
-
Hall J., Husken D., Pieles U., et al. Efficient sequence-specific cleavage of RNA using novel europium complexes conjugated to oligonucleotides. Chem. Biol. 1 (1994) 185
-
(1994)
Chem. Biol.
, vol.1
, pp. 185
-
-
Hall, J.1
Husken, D.2
Pieles, U.3
-
88
-
-
0027104702
-
Antisense and antigene properties of peptide nucleic acids
-
Hanvey J.C., Peffer N.J., Bisi J.E., et al. Antisense and antigene properties of peptide nucleic acids. Science 258 (1992) 1481
-
(1992)
Science
, vol.258
, pp. 1481
-
-
Hanvey, J.C.1
Peffer, N.J.2
Bisi, J.E.3
-
89
-
-
0023227831
-
A c-myc antisense oligonucleotide inhibits entry into S phase but not progress from G0 to G1
-
Heikkila R., Schwab G., and Wickström E. A c-myc antisense oligonucleotide inhibits entry into S phase but not progress from G0 to G1. Nature (London) 328 (1987) 445
-
(1987)
Nature (London)
, vol.328
, pp. 445
-
-
Heikkila, R.1
Schwab, G.2
Wickström, E.3
-
90
-
-
0027310376
-
c-fos antisense in the nucleus accumbens blocks the locomotor stimulant action of cocaine
-
Heilig M., Engel J.A., and Soderpalm B. c-fos antisense in the nucleus accumbens blocks the locomotor stimulant action of cocaine. Eur. J. Pharmacol. 236 (1993) 339
-
(1993)
Eur. J. Pharmacol.
, vol.236
, pp. 339
-
-
Heilig, M.1
Engel, J.A.2
Soderpalm, B.3
-
91
-
-
0039121646
-
Control of gene expression by oligonucleotides covalently linked to intercalating agents and nucleic acid-cleaving reagents
-
Cohen J.S. (Ed), CRC Press, Boca Raton, Florida.
-
Helene C., and Toulme J.J. Control of gene expression by oligonucleotides covalently linked to intercalating agents and nucleic acid-cleaving reagents. In: Cohen J.S. (Ed). Oligodeoxynucleotides: Antisense Inhibitors of Gene Expression (1989), CRC Press, Boca Raton, Florida. 137
-
(1989)
Oligodeoxynucleotides: Antisense Inhibitors of Gene Expression
, pp. 137
-
-
Helene, C.1
Toulme, J.J.2
-
92
-
-
0031036843
-
Comparison of the toxicities profile of ISIS 1082 and ISIS 2105, phosphorothioate oligonucleotides, following subacute intradermal administration in Sprague-Dawley rats
-
Henry S.P., Orr J.L., Bruner R.H., et al. Comparison of the toxicities profile of ISIS 1082 and ISIS 2105, phosphorothioate oligonucleotides, following subacute intradermal administration in Sprague-Dawley rats. Toxicology 116 1-3 (1997) 77-88
-
(1997)
Toxicology
, vol.116
, Issue.1-3
, pp. 77-88
-
-
Henry, S.P.1
Orr, J.L.2
Bruner, R.H.3
-
93
-
-
0030806664
-
Evaluation of the toxicity profile of ISIS 2302, a phosphorothioate oligonucleotide. 1. 4-week study in CD-I mice
-
In press
-
Henry S.P., Taylor J., Midgley L., et al. Evaluation of the toxicity profile of ISIS 2302, a phosphorothioate oligonucleotide. 1. 4-week study in CD-I mice. Antisense Nucleic Drug Dev. (1997) In press
-
(1997)
Antisense Nucleic Drug Dev.
-
-
Henry, S.P.1
Taylor, J.2
Midgley, L.3
-
94
-
-
0030918233
-
Evaluation of the toxicity of ISIS 2302, a phosphorothioate oligonucleotide. 2. 4-week study in cynomolgus monkeys
-
In press
-
Henry S.P., Bolte H., Auletta C., et al. Evaluation of the toxicity of ISIS 2302, a phosphorothioate oligonucleotide. 2. 4-week study in cynomolgus monkeys. Toxicology (1997) In press
-
(1997)
Toxicology
-
-
Henry, S.P.1
Bolte, H.2
Auletta, C.3
-
95
-
-
0030922755
-
Activation of the alternative pathway of complement by a phosphorothioate oligonucleotide: Potential mechanism of action
-
In press
-
Henry S.P., Giclas P., Leeds J., et al. Activation of the alternative pathway of complement by a phosphorothioate oligonucleotide: Potential mechanism of action. J. Pharmacol. Exp. Ther. (1997) In press
-
(1997)
J. Pharmacol. Exp. Ther.
-
-
Henry, S.P.1
Giclas, P.2
Leeds, J.3
-
96
-
-
77956754086
-
Inhibition of clotting parameters by a phosphorothioate oligonucleotide
-
In preparation
-
S.P. Henry, W. Novotny, J. Leeds, (1997e). Inhibition of clotting parameters by a phosphorothioate oligonucleotide. In preparation.
-
(1997)
-
-
Henry, S.P.1
Novotny, W.2
Leeds, J.3
-
97
-
-
0031018954
-
Toxicologic properties of several novel oligonucleotide analogs in mice
-
Henry S.P., Zuckerman J.E., Rojko J., et al. Toxicologic properties of several novel oligonucleotide analogs in mice. Anti-cancer Drug Des. 12 1 (1997) 1-14
-
(1997)
Anti-cancer Drug Des.
, vol.12
, Issue.1
, pp. 1-14
-
-
Henry, S.P.1
Zuckerman, J.E.2
Rojko, J.3
-
98
-
-
0028989878
-
Inhibition of interferon-γ-induced intercellular adhesion molecule-1 expression on human keratinocytes by phosphorothioate antisense oligodeoxynucleotides is the consequence of antisense-specific and antisense-non-specific effects
-
Hertl M., Neckers L.M., and Katz S.I. Inhibition of interferon-γ-induced intercellular adhesion molecule-1 expression on human keratinocytes by phosphorothioate antisense oligodeoxynucleotides is the consequence of antisense-specific and antisense-non-specific effects. J. Invest. Dermatol. 104 (1995) 813
-
(1995)
J. Invest. Dermatol.
, vol.104
, pp. 813
-
-
Hertl, M.1
Neckers, L.M.2
Katz, S.I.3
-
99
-
-
0027377107
-
Antisense inhibition of the p65 subunit of NF-B blocks tumorigenicity and causes tumor regression
-
Higgins K.A., Perez J.R., Coleman T.A., et al. Antisense inhibition of the p65 subunit of NF-B blocks tumorigenicity and causes tumor regression. Proc. Natl. Acad. Sci. U.S.A. 90 (1993) 9901
-
(1993)
Proc. Natl. Acad. Sci. U.S.A.
, vol.90
, pp. 9901
-
-
Higgins, K.A.1
Perez, J.R.2
Coleman, T.A.3
-
100
-
-
0028325486
-
Biological and therapeutic significance of MYB expression in human melanoma
-
Hijiya N., Zhang J., Ratajczak M.Z., et al. Biological and therapeutic significance of MYB expression in human melanoma. Proc. Natl. Acad. Sci. U.S.A. 91 (1994) 4499
-
(1994)
Proc. Natl. Acad. Sci. U.S.A.
, vol.91
, pp. 4499
-
-
Hijiya, N.1
Zhang, J.2
Ratajczak, M.Z.3
-
101
-
-
0028822483
-
Inhibition of wild-type and mutated luciferase-adenovirus pre-mRNAs by antisense oligonucleotides
-
Hodges D., and Crooke S.T. Inhibition of wild-type and mutated luciferase-adenovirus pre-mRNAs by antisense oligonucleotides. Mol. Pharmacol. 48 (1995) 905
-
(1995)
Mol. Pharmacol.
, vol.48
, pp. 905
-
-
Hodges, D.1
Crooke, S.T.2
-
102
-
-
0026048056
-
Effects of phosphorothioate capping on antisense oligonucleotide stability, hybridization and antiviral efficacy versus herpes simplex virus infection
-
Hoke G.D., Draper K., Freier S.M., et al. Effects of phosphorothioate capping on antisense oligonucleotide stability, hybridization and antiviral efficacy versus herpes simplex virus infection. Nucleic Acids Res. 19 (1991) 5743
-
(1991)
Nucleic Acids Res.
, vol.19
, pp. 5743
-
-
Hoke, G.D.1
Draper, K.2
Freier, S.M.3
-
103
-
-
0028150874
-
Infusion into the brain of an antisense oligonucleotide to the immediate-early gene c-fos suppresses production of fos and produces a behavioral effect
-
Hooper M.L., Chiasson B.J., and Robertson H.A. Infusion into the brain of an antisense oligonucleotide to the immediate-early gene c-fos suppresses production of fos and produces a behavioral effect. Neuroscience 63 (1994) 917
-
(1994)
Neuroscience
, vol.63
, pp. 917
-
-
Hooper, M.L.1
Chiasson, B.J.2
Robertson, H.A.3
-
104
-
-
0029077765
-
Radiolabeling of methylphosphonate and phosphorothioate oligonucleotides and evaluation of their transport in everted rat jejunum sacs
-
Hughes J.A., Avrutskaya A.V., Brouwer K.L.R., et al. Radiolabeling of methylphosphonate and phosphorothioate oligonucleotides and evaluation of their transport in everted rat jejunum sacs. Pharmacol. Res. 12 (1995) 817
-
(1995)
Pharmacol. Res.
, vol.12
, pp. 817
-
-
Hughes, J.A.1
Avrutskaya, A.V.2
Brouwer, K.L.R.3
-
106
-
-
0022423650
-
Synthesis and hybridization of dodecadeoxyribonucleotides containing a fluorescent pyridopyrimidine deoxynucleoside
-
Inoue H., and Ohtsuka E. Synthesis and hybridization of dodecadeoxyribonucleotides containing a fluorescent pyridopyrimidine deoxynucleoside. Nucleic Acids Res. 13 (1985) 7119
-
(1985)
Nucleic Acids Res.
, vol.13
, pp. 7119
-
-
Inoue, H.1
Ohtsuka, E.2
-
107
-
-
0026335873
-
In vivo studies with phosphorothioate oligonucleotides: Pharamcokinetic prologue.
-
Iversen P. In vivo studies with phosphorothioate oligonucleotides: Pharamcokinetic prologue. Anti-Cancer Drug Des. 6 (1991) 531
-
(1991)
Anti-Cancer Drug Des.
, vol.6
, pp. 531
-
-
Iversen, P.1
-
108
-
-
0014481514
-
Determination of binding constants of serum albumin for penicillin
-
Joos R.W., and Hall W.H. Determination of binding constants of serum albumin for penicillin. J. Pharmacol. Exp. Ther. 166 (1969) 113
-
(1969)
J. Pharmacol. Exp. Ther.
, vol.166
, pp. 113
-
-
Joos, R.W.1
Hall, W.H.2
-
109
-
-
0027479864
-
Uniformly modified 2-deoxy-2-fluoro phosphorothioate oligonucleotides as nuclease resistant antisense compounds with high affinity and specificity for RNA targets
-
Kawasaki A.M., Casper M.D., Freier S.M., et al. Uniformly modified 2-deoxy-2-fluoro phosphorothioate oligonucleotides as nuclease resistant antisense compounds with high affinity and specificity for RNA targets. J. Med. Chem. 36 (1993) 831
-
(1993)
J. Med. Chem.
, vol.36
, pp. 831
-
-
Kawasaki, A.M.1
Casper, M.D.2
Freier, S.M.3
-
110
-
-
0028177208
-
NMDA receptor inhibition using antisense oligonucleotides prevents delayed neuronal death in gerbil hippocampus following cerebral ischemia
-
Kindy M.S. NMDA receptor inhibition using antisense oligonucleotides prevents delayed neuronal death in gerbil hippocampus following cerebral ischemia. Neurosci. Res. Commun. 14 (1994) 175
-
(1994)
Neurosci. Res. Commun.
, vol.14
, pp. 175
-
-
Kindy, M.S.1
-
111
-
-
0027058137
-
Ablation of transplanted HTLV-1 tax-transformed tumors in mice by antisense inhibition of NF-B
-
Kitajima I., Shinohara T., Bilakovics J., et al. Ablation of transplanted HTLV-1 tax-transformed tumors in mice by antisense inhibition of NF-B. Science 258 (1992) 1792
-
(1992)
Science
, vol.258
, pp. 1792
-
-
Kitajima, I.1
Shinohara, T.2
Bilakovics, J.3
-
112
-
-
0028018276
-
Amphetamine regulates gene expression in rat striatum via transcription factor CREB
-
Konradi C., Cole R.L., Heckers S., et al. Amphetamine regulates gene expression in rat striatum via transcription factor CREB. J. Neurosci. 14 (1994) 5623
-
(1994)
J. Neurosci.
, vol.14
, pp. 5623
-
-
Konradi, C.1
Cole, R.L.2
Heckers, S.3
-
113
-
-
0028931102
-
CpG motifs in bacterial DNA trigger direct B-cell activation
-
Krieg A.M., Yi A.-K., and Matson S. CpG motifs in bacterial DNA trigger direct B-cell activation. Nature (London) 374 (1995) 546
-
(1995)
Nature (London)
, vol.374
, pp. 546
-
-
Krieg, A.M.1
Yi, A.-K.2
Matson, S.3
-
114
-
-
0007684104
-
Site specificity of the inhibitory effects of oligo(nucleoside methylphosphonates) complementary to the acceptor splice junction of herpes simplex virus type 1 immediately early mRNA
-
Kulka M., Smith C., Aurelian L., et al. Site specificity of the inhibitory effects of oligo(nucleoside methylphosphonates) complementary to the acceptor splice junction of herpes simplex virus type 1 immediately early mRNA. Proc. Natl. Acad. Sci. U.S.A. 86 (1989) 6868
-
(1989)
Proc. Natl. Acad. Sci. U.S.A.
, vol.86
, pp. 6868
-
-
Kulka, M.1
Smith, C.2
Aurelian, L.3
-
115
-
-
0027052546
-
Oligonucleotide sequences required for natural killer cell activation
-
Kuramoto E., Yano O., Kimura Y., et al. Oligonucleotide sequences required for natural killer cell activation. Jpn. J. Cancer Res. 83 (1992) 1128
-
(1992)
Jpn. J. Cancer Res.
, vol.83
, pp. 1128
-
-
Kuramoto, E.1
Yano, O.2
Kimura, Y.3
-
117
-
-
0027254030
-
Antisense oligonucleotides made of 2-O-alkyl RNA: Their properties and applications in RNA biochemistry
-
Lamond A.I., and Sproat B.S. Antisense oligonucleotides made of 2-O-alkyl RNA: Their properties and applications in RNA biochemistry. FEBS Lett. 325 (1993) 123
-
(1993)
FEBS Lett.
, vol.325
, pp. 123
-
-
Lamond, A.I.1
Sproat, B.S.2
-
118
-
-
0000359889
-
Specific antiviral activity of a poly(l-lysine)-conjugated oligodeoxyribonucleotide sequence complementary to vesicular stomatitis virus N-protein mRNA initiation site
-
Lemaitre M., Bayard B., and Lebleu B. Specific antiviral activity of a poly(l-lysine)-conjugated oligodeoxyribonucleotide sequence complementary to vesicular stomatitis virus N-protein mRNA initiation site. Proc. Natl. Acad. Sci. U.S.A. 84 (1987) 648
-
(1987)
Proc. Natl. Acad. Sci. U.S.A.
, vol.84
, pp. 648
-
-
Lemaitre, M.1
Bayard, B.2
Lebleu, B.3
-
119
-
-
0028973118
-
1 receptor antisense oligodeoxynucleotide into the central nucleus of the amygdala reduced anxiety-related behavior in socially defeated rats
-
1 receptor antisense oligodeoxynucleotide into the central nucleus of the amygdala reduced anxiety-related behavior in socially defeated rats. Regul. Pept. 59 (1995) 229
-
(1995)
Regul. Pept.
, vol.59
, pp. 229
-
-
Liebsch, G.1
Landgraf, R.2
Gerstberger, R.3
-
120
-
-
0026621339
-
Implication of RNA structure on antisense oligonucleotide hybridization kinetics
-
Lima W.F., Monia B.P., Ecker D.J., et al. Implication of RNA structure on antisense oligonucleotide hybridization kinetics. Biochemistry 31 (1992) 12055
-
(1992)
Biochemistry
, vol.31
, pp. 12055
-
-
Lima, W.F.1
Monia, B.P.2
Ecker, D.J.3
-
121
-
-
0024787895
-
Synthesis and duplex stability of oligonucleotides containing cytosine-thymine analogues
-
Lin K.T.P., and Brown D.M. Synthesis and duplex stability of oligonucleotides containing cytosine-thymine analogues. Nucleic Acids Res. 17 (1989) 10373
-
(1989)
Nucleic Acids Res.
, vol.17
, pp. 10373
-
-
Lin, K.T.P.1
Brown, D.M.2
-
122
-
-
0028908575
-
Tricyclic-2-deoxycytidine analogs: Syntheses and incorporation into oligodeoxynucleotides which have enhanced binding to complementary RNA
-
Lin K.-Y., Jone R.J., and Matteucci M. Tricyclic-2-deoxycytidine analogs: Syntheses and incorporation into oligodeoxynucleotides which have enhanced binding to complementary RNA. J. Am. Chem. Soc. 117 (1995) 3873
-
(1995)
J. Am. Chem. Soc.
, vol.117
, pp. 3873
-
-
Lin, K.-Y.1
Jone, R.J.2
Matteucci, M.3
-
123
-
-
0345570537
-
Characterization of oligonucleotide transport into living cells
-
Loke S.L., Stein C.A., Zhang X.H., et al. Characterization of oligonucleotide transport into living cells. Proc. Natl. Acad. Sci. U.S.A. 86 (1989) 3474
-
(1989)
Proc. Natl. Acad. Sci. U.S.A.
, vol.86
, pp. 3474
-
-
Loke, S.L.1
Stein, C.A.2
Zhang, X.H.3
-
124
-
-
0024357372
-
Inhibition of DNA binding properties by oligonucleotide-directed triple helix formation
-
Maher III J.L., Wold B., and Dervan P.G. Inhibition of DNA binding properties by oligonucleotide-directed triple helix formation. Science 245 (1989) 725
-
(1989)
Science
, vol.245
, pp. 725
-
-
Maher III, J.L.1
Wold, B.2
Dervan, P.G.3
-
125
-
-
0025186452
-
Extension of the life-span of human endothelial cells by an interleukin-1α antisense oligomer
-
Maier J.A.M., Voulalas P., Roeder D., et al. Extension of the life-span of human endothelial cells by an interleukin-1α antisense oligomer. Science 249 (1990) 1570
-
(1990)
Science
, vol.249
, pp. 1570
-
-
Maier, J.A.M.1
Voulalas, P.2
Roeder, D.3
-
126
-
-
0024505583
-
Stepwise mechanism of HIV reverse transcriptase: Primer function of phosphorothioate oligodeoxynucleotide
-
Majumdar C., Stein C.A., Cohen J.S., et al. Stepwise mechanism of HIV reverse transcriptase: Primer function of phosphorothioate oligodeoxynucleotide. Biochemistry 28 (1989) 1340
-
(1989)
Biochemistry
, vol.28
, pp. 1340
-
-
Majumdar, C.1
Stein, C.A.2
Cohen, J.S.3
-
127
-
-
0028136392
-
Inhibition of rat sexual behavior by antisense oligonucleotides to the progesterone receptor
-
Mani S.K., Blaustein J.D., and Allen J.M.C. Inhibition of rat sexual behavior by antisense oligonucleotides to the progesterone receptor. Endocrinology (Baltimore) 135 (1994) 278
-
(1994)
Endocrinology (Baltimore)
, vol.135
, pp. 278
-
-
Mani, S.K.1
Blaustein, J.D.2
Allen, J.M.C.3
-
128
-
-
0001674585
-
Designer antisense oligonucleotides: Conjugation chemistry and functionality placement
-
Crooke S.T., and Lebleu B. (Eds), CRC Press, Boca Raton, Florida.
-
Manoharan M. Designer antisense oligonucleotides: Conjugation chemistry and functionality placement. In: Crooke S.T., and Lebleu B. (Eds). Antisense Research and Therapeutics (1993), CRC Press, Boca Raton, Florida. 303
-
(1993)
Antisense Research and Therapeutics
, pp. 303
-
-
Manoharan, M.1
-
129
-
-
0023261982
-
Comparative inhibition of chloramphenicol acetyltransferase gene expression by antisense oligonucleotide analogues having alkyl phosphotriester, methylphosphonate and phosphorothioate linkages
-
Marcus-Sekura C.J., Woerner A.M., Shinozuka K., et al. Comparative inhibition of chloramphenicol acetyltransferase gene expression by antisense oligonucleotide analogues having alkyl phosphotriester, methylphosphonate and phosphorothioate linkages. Nucleic Acids Res. 15 (1987) 5749
-
(1987)
Nucleic Acids Res.
, vol.15
, pp. 5749
-
-
Marcus-Sekura, C.J.1
Woerner, A.M.2
Shinozuka, K.3
-
130
-
-
0022429804
-
Base pairing involving deoxyinosine: Implications for probe design
-
Martin F.H., Castro M.M., Aboul-ela F., et al. Base pairing involving deoxyinosine: Implications for probe design. Nucleic Acids Res. 13 (1985) 8927
-
(1985)
Nucleic Acids Res.
, vol.13
, pp. 8927
-
-
Martin, F.H.1
Castro, M.M.2
Aboul-ela, F.3
-
131
-
-
0029099305
-
New access to 2-O-alkylated ribonucleosides and properties of 2-O-alkylated oligoribonucleotides
-
Martin P. New access to 2-O-alkylated ribonucleosides and properties of 2-O-alkylated oligoribonucleotides. Helv. Chitn. Acta 78 (1995) 486
-
(1995)
Helv. Chitn. Acta
, vol.78
, pp. 486
-
-
Martin, P.1
-
132
-
-
0023447274
-
Phosphorothioate analogs of oligodeoxyribonucleotides: Inhibitors of replication and cytopathic effects of human immunodeficiency virus
-
Matsukura M., Shinozuka K., Zon G., et al. Phosphorothioate analogs of oligodeoxyribonucleotides: Inhibitors of replication and cytopathic effects of human immunodeficiency virus. Proc. Natl. Acad. Sci. U.S.A. 84 (1987) 7706
-
(1987)
Proc. Natl. Acad. Sci. U.S.A.
, vol.84
, pp. 7706
-
-
Matsukura, M.1
Shinozuka, K.2
Zon, G.3
-
134
-
-
0028876310
-
Antisense oligonucleotide inhibition of tryptophan hydroxylase activity in mouse brain
-
McCarthy M.M., Nielsen D.A., and Goldman D. Antisense oligonucleotide inhibition of tryptophan hydroxylase activity in mouse brain. Regul. Pept. 59 (1995) 163
-
(1995)
Regul. Pept.
, vol.59
, pp. 163
-
-
McCarthy, M.M.1
Nielsen, D.A.2
Goldman, D.3
-
135
-
-
0025312339
-
Tumour-specific inhibition of lymphoma growth by an antisense oligodeoxynucleotide
-
McManaway M.E., Neckers L.M., Loke S.L., et al. Tumour-specific inhibition of lymphoma growth by an antisense oligodeoxynucleotide. Lancet 335 (1990) 808
-
(1990)
Lancet
, vol.335
, pp. 808
-
-
McManaway, M.E.1
Neckers, L.M.2
Loke, S.L.3
-
136
-
-
0026006734
-
Stimulation of in vitro murine lymphocyte proliferation by bacterial DNA
-
Messina J.P., Gilkeson G.S., and Pisetsky D.S. Stimulation of in vitro murine lymphocyte proliferation by bacterial DNA. J. Immunol. 147 (1991) 1759
-
(1991)
J. Immunol.
, vol.147
, pp. 1759
-
-
Messina, J.P.1
Gilkeson, G.S.2
Pisetsky, D.S.3
-
138
-
-
0023057552
-
The use of single-stranded DNA and RNase H to promote quantitative hybrid arrest of translation of mRNA/DNA hybrids in reticulocyte lysate cell-free translations
-
Minshull J., and Hunt T. The use of single-stranded DNA and RNase H to promote quantitative hybrid arrest of translation of mRNA/DNA hybrids in reticulocyte lysate cell-free translations. Nucleic Acids Res. 14 (1986) 6433
-
(1986)
Nucleic Acids Res.
, vol.14
, pp. 6433
-
-
Minshull, J.1
Hunt, T.2
-
139
-
-
0002468854
-
Antisense oligonucleotides in the context of modern molecular drug discovery and development
-
Crooke S.T., and Lebleu B. (Eds), CRC Press, Boca Raton, Florida.
-
Mirabelli C.K., and Crooke S.T. Antisense oligonucleotides in the context of modern molecular drug discovery and development. In: Crooke S.T., and Lebleu B. (Eds). Antisense Research and Applications (1993), CRC Press, Boca Raton, Florida. 7
-
(1993)
Antisense Research and Applications
, pp. 7
-
-
Mirabelli, C.K.1
Crooke, S.T.2
-
140
-
-
0026356573
-
In vitro and in vivo pharmacologic activities of antisense oligonucleotides.
-
Mirabelli C.K., Bennett C.F., Anderson K., et al. In vitro and in vivo pharmacologic activities of antisense oligonucleotides. Anti-Cancer Drug Des. 6 (1991) 647
-
(1991)
Anti-Cancer Drug Des.
, vol.6
, pp. 647
-
-
Mirabelli, C.K.1
Bennett, C.F.2
Anderson, K.3
-
141
-
-
0029160070
-
Stability and pharmacokinetic characteristics of oligonucleotides modified at terminal linkages in mice
-
Miyao T., Takakura Y., Akiyama T., et al. Stability and pharmacokinetic characteristics of oligonucleotides modified at terminal linkages in mice. Antisense Res. Dev. 5 (1995) 115
-
(1995)
Antisense Res. Dev.
, vol.5
, pp. 115
-
-
Miyao, T.1
Takakura, Y.2
Akiyama, T.3
-
142
-
-
0028793465
-
Antisense oligodeoxynucleotide to a δ-opioid receptor blocks the antinociception induced by cold water swimming
-
Mizoguchi H., Narita M., Nagase H., et al. Antisense oligodeoxynucleotide to a δ-opioid receptor blocks the antinociception induced by cold water swimming. Regul. Pept. 59 (1995) 255
-
(1995)
Regul. Pept.
, vol.59
, pp. 255
-
-
Mizoguchi, H.1
Narita, M.2
Nagase, H.3
-
143
-
-
0026774939
-
Selective inhibition of mutant Ha-ras mRNA expression by antisense oligonucleotides
-
Monia B.P., Johnston J.F., Ecker D.J., et al. Selective inhibition of mutant Ha-ras mRNA expression by antisense oligonucleotides. J. Biol. Chem. 267 (1992) 19954
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 19954
-
-
Monia, B.P.1
Johnston, J.F.2
Ecker, D.J.3
-
144
-
-
0027168725
-
Evaluation of 2-modified oligonucleotides containing 2-deoxy gaps as antisense inhibitors of gene expression
-
Monia B.P., Lesnik E.A., and Gonzalez C. Evaluation of 2-modified oligonucleotides containing 2-deoxy gaps as antisense inhibitors of gene expression. J. Biol. Chem. 268 (1993)
-
(1993)
J. Biol. Chem.
, vol.268
-
-
Monia, B.P.1
Lesnik, E.A.2
Gonzalez, C.3
-
145
-
-
0029977448
-
Antitumor activity of a phosphorothioate antisense oligodeoxynucleotide targeted against c-raf kinase
-
Monia B.P., Johnston J.F., Geiger T., et al. Antitumor activity of a phosphorothioate antisense oligodeoxynucleotide targeted against c-raf kinase. Nat. Med. 2 6 (1996) 668-675
-
(1996)
Nat. Med.
, vol.2
, Issue.6
, pp. 668-675
-
-
Monia, B.P.1
Johnston, J.F.2
Geiger, T.3
-
146
-
-
15844400778
-
Nuclease resistance and antisense activity of modified oligonucleotides targeted to Ha-ras
-
Monia B.P., Johnston J.F., and Sasmor H. Nuclease resistance and antisense activity of modified oligonucleotides targeted to Ha-ras. J. Biol. Chem. 271 24 (1996) 14533-14540
-
(1996)
J. Biol. Chem.
, vol.271
, Issue.24
, pp. 14533-14540
-
-
Monia, B.P.1
Johnston, J.F.2
Sasmor, H.3
-
147
-
-
0027323303
-
Single intraluminal delivery of antisense cdc2 kinase and proliferating-cell nuclear antigen oligonucleotides results in chronic inhibition of neointimal hyperplasia
-
Morishita R., Gibbons G.H., Ellison K.E., et al. Single intraluminal delivery of antisense cdc2 kinase and proliferating-cell nuclear antigen oligonucleotides results in chronic inhibition of neointimal hyperplasia. Proc. Natl. Acad. Sci. U.S.A. 90 (1993) 8474
-
(1993)
Proc. Natl. Acad. Sci. U.S.A.
, vol.90
, pp. 8474
-
-
Morishita, R.1
Gibbons, G.H.2
Ellison, K.E.3
-
148
-
-
0027960909
-
1 and CDC 2 kinase) in the vessel wall in vivo: Enhanced therapeutic utility for restenosis by HVJ-liposome delivery
-
1 and CDC 2 kinase) in the vessel wall in vivo: Enhanced therapeutic utility for restenosis by HVJ-liposome delivery. Gene 149 (1994) 13
-
(1994)
Gene
, vol.149
, pp. 13
-
-
Morishita, R.1
Gibbons, G.H.2
Kaneda, Y.3
-
149
-
-
0026323454
-
α-Oligonucleotides: A unique class of modified chimeric nucleic acids
-
Morvan F., Rayner B., and Imbach J.-L. α-Oligonucleotides: A unique class of modified chimeric nucleic acids. Anti-Cancer Drug Des. 6 (1991) 521
-
(1991)
Anti-Cancer Drug Des.
, vol.6
, pp. 521
-
-
Morvan, F.1
Rayner, B.2
Imbach, J.-L.3
-
151
-
-
0001014648
-
Cellular internalization of oligodeoxynucleotides
-
Crooke S.T., and Lebleu B. (Eds), CRC Press, Boca Raton, Florida.
-
Neckers L.M. Cellular internalization of oligodeoxynucleotides. In: Crooke S.T., and Lebleu B. (Eds). Antisense Research and Applications (1993), CRC Press, Boca Raton, Florida. 451
-
(1993)
Antisense Research and Applications
, pp. 451
-
-
Neckers, L.M.1
-
152
-
-
0029050664
-
A single injection protein kinase α-directed antisense treatment to inhibit tumor growth
-
Nesterova M., and Cho-Chung Y.S. A single injection protein kinase α-directed antisense treatment to inhibit tumor growth. Nat. Med. 1 (1995) 528
-
(1995)
Nat. Med.
, vol.1
, pp. 528
-
-
Nesterova, M.1
Cho-Chung, Y.S.2
-
153
-
-
0028056021
-
Rapid effect on suckling of an oxytocin antisense oligonucleotide administered into rat supraoptc nucleus
-
Neumann I., Porter D.W.F., Landgraf R., et al. Rapid effect on suckling of an oxytocin antisense oligonucleotide administered into rat supraoptc nucleus. Bull. Am. Phys. Soc. (1994) R852
-
(1994)
Bull. Am. Phys. Soc.
-
-
Neumann, I.1
Porter, D.W.F.2
Landgraf, R.3
-
154
-
-
0025767285
-
The synthesis of oligodeoxynucleotides containing 4-thiothymidine residues
-
Nikiforov T.T., and Connolly B.A. The synthesis of oligodeoxynucleotides containing 4-thiothymidine residues. Tetrahedron Lett. 32 (1991) 3851
-
(1991)
Tetrahedron Lett.
, vol.32
, pp. 3851
-
-
Nikiforov, T.T.1
Connolly, B.A.2
-
155
-
-
0027528518
-
In vivo inhibition of duck hepatitis B virus replication and gene expression by phosphorothioate modified antisense oligodeoxynucleotides.
-
Offensperger W.-B., Offensperger S., Walter E., et al. In vivo inhibition of duck hepatitis B virus replication and gene expression by phosphorothioate modified antisense oligodeoxynucleotides. EMBO J. 12 (1993) 1257
-
(1993)
EMBO J.
, vol.12
, pp. 1257
-
-
Offensperger, W.-B.1
Offensperger, S.2
Walter, E.3
-
156
-
-
0027988645
-
Modulation of substance P/neurokinin-1 receptor in human astrocytoma cells by antisense oligodeoxynucleotides
-
Ogo H., Hirai Y., Miki S., et al. Modulation of substance P/neurokinin-1 receptor in human astrocytoma cells by antisense oligodeoxynucleotides. Gen. Pharmacol. 25 (1994) 1131
-
(1994)
Gen. Pharmacol.
, vol.25
, pp. 1131
-
-
Ogo, H.1
Hirai, Y.2
Miki, S.3
-
157
-
-
0027306854
-
Inhibition of axonal growth by SNAP-25 antisense oligonucleotides in vitro and in vivo
-
Osen-Sand A., Catsicas M., and Staple J.K. Inhibition of axonal growth by SNAP-25 antisense oligonucleotides in vitro and in vivo. Nature (London) 364 (1993) 445
-
(1993)
Nature (London)
, vol.364
, pp. 445
-
-
Osen-Sand, A.1
Catsicas, M.2
Staple, J.K.3
-
158
-
-
0028337111
-
A convergent synthesis of 2-O-methyl uridine
-
Parmentier G., Schmitt G., Dolle F., et al. A convergent synthesis of 2-O-methyl uridine. Tetrahedron 50 (1994) 5361
-
(1994)
Tetrahedron
, vol.50
, pp. 5361
-
-
Parmentier, G.1
Schmitt, G.2
Dolle, F.3
-
159
-
-
0027469799
-
Growth inhibition of human tumor cell lines by antisense oligonucleotides designed to inhibit p120 expression
-
Perlaky L., Saijo Y., Busch R.K., et al. Growth inhibition of human tumor cell lines by antisense oligonucleotides designed to inhibit p120 expression. Anti-Cancer Drug Des. 8 (1993) 3
-
(1993)
Anti-Cancer Drug Des.
, vol.8
, pp. 3
-
-
Perlaky, L.1
Saijo, Y.2
Busch, R.K.3
-
160
-
-
0028151713
-
Antisense inhibition of hypertension: A new strategy for renin-angiotensin candidate genes
-
Phillips M.I., Wielbo D., and Gyurko R. Antisense inhibition of hypertension: A new strategy for renin-angiotensin candidate genes. Kidney Int. 46 (1994) 1554
-
(1994)
Kidney Int.
, vol.46
, pp. 1554
-
-
Phillips, M.I.1
Wielbo, D.2
Gyurko, R.3
-
161
-
-
84987367507
-
Pyranosyl-RNA ("p-RNA"): Base-pairing selectivity and potential to replicate
-
Pitsch S., Krishnamurthy R., Bolli M., et al. Pyranosyl-RNA ("p-RNA"): Base-pairing selectivity and potential to replicate. Helv. Chim. Acta 78 (1995) 1621
-
(1995)
Helv. Chim. Acta
, vol.78
, pp. 1621
-
-
Pitsch, S.1
Krishnamurthy, R.2
Bolli, M.3
-
162
-
-
0027213081
-
Antisense oligonucleotide blocks progesterone-induced lordosis behavior in ovariectomized rats
-
Pollio G., Xue P., Zanisi M., et al. Antisense oligonucleotide blocks progesterone-induced lordosis behavior in ovariectomized rats. Mol. Brain Res. 19 (1993) 135
-
(1993)
Mol. Brain Res.
, vol.19
, pp. 135
-
-
Pollio, G.1
Xue, P.2
Zanisi, M.3
-
163
-
-
0027954331
-
Stimulation of murine lymphocyte proliferation by a phosphorothioate oligonucleotide with antisense activity for herpes simplex virus
-
Psietsky D.S., and Reich C.F. Stimulation of murine lymphocyte proliferation by a phosphorothioate oligonucleotide with antisense activity for herpes simplex virus. Life Sci. 54 (1993) 101
-
(1993)
Life Sci.
, vol.54
, pp. 101
-
-
Psietsky, D.S.1
Reich, C.F.2
-
165
-
-
0024425723
-
Number and distribution of methylphosphonate linkages in oligodeoxynucleotides affect exo- and endonuclease sensitivity and ability to form RNase H substrates
-
Quartin R., Brakel C., and Wetmur J. Number and distribution of methylphosphonate linkages in oligodeoxynucleotides affect exo- and endonuclease sensitivity and ability to form RNase H substrates. Nucleic Acids Res. 17 (1989) 7253
-
(1989)
Nucleic Acids Res.
, vol.17
, pp. 7253
-
-
Quartin, R.1
Brakel, C.2
Wetmur, J.3
-
166
-
-
0028610299
-
Intracellular enhancement of intact antisense oligonucleotide steady-state levels by cationic lipids
-
Quattrone A., Papucci L., Schiavone, et al. Intracellular enhancement of intact antisense oligonucleotide steady-state levels by cationic lipids. Anti-Cancer Drug Des. 9 (1994) 549
-
(1994)
Anti-Cancer Drug Des.
, vol.9
, pp. 549
-
-
Quattrone, A.1
Papucci, L.2
Schiavone3
-
167
-
-
0029031695
-
Transport of phosphorothioate oligonucleotides in kidney: Implications for molecular therapy
-
Rappaport J., Hanss B., Kopp J.B., et al. Transport of phosphorothioate oligonucleotides in kidney: Implications for molecular therapy. Kidney Int. 47 (1995) 1462
-
(1995)
Kidney Int.
, vol.47
, pp. 1462
-
-
Rappaport, J.1
Hanss, B.2
Kopp, J.B.3
-
168
-
-
0027070730
-
In vivo treatment of human leukemia in a scid mouse model with c-myb antisense oligodeoxynucleotides.
-
Ratajczak M.Z., Kant J.A., Luger S.M., et al. In vivo treatment of human leukemia in a scid mouse model with c-myb antisense oligodeoxynucleotides. Proc. Natl. Acad. Sci. U.S.A. 89 (1992) 11823
-
(1992)
Proc. Natl. Acad. Sci. U.S.A.
, vol.89
, pp. 11823
-
-
Ratajczak, M.Z.1
Kant, J.A.2
Luger, S.M.3
-
169
-
-
0025050969
-
Antisense inhibition of single copy N-myc expression results in decreased cell growth without reduction of c-myc protein in a neuroepithelioma cell line
-
Rosolen A., Whitesell L., Olegalo M., et al. Antisense inhibition of single copy N-myc expression results in decreased cell growth without reduction of c-myc protein in a neuroepithelioma cell line. Cancer Res. 50 (1990) 6316
-
(1990)
Cancer Res.
, vol.50
, pp. 6316
-
-
Rosolen, A.1
Whitesell, L.2
Olegalo, M.3
-
170
-
-
0028788962
-
1) receptor antisense oligonucleotide attenuates thirst in the rat
-
1) receptor antisense oligonucleotide attenuates thirst in the rat. Regul. Pept. 59 (1995) 183
-
(1995)
Regul. Pept.
, vol.59
, pp. 183
-
-
Sakai, R.R.1
Ma, L.Y.2
He, P.F.3
-
171
-
-
0028241377
-
3H-labeled oligonucleotides. I. Comparion of a phosphodiester and a phosphorothioate
-
3H-labeled oligonucleotides. I. Comparion of a phosphodiester and a phosphorothioate. Mol. Pharmacol. 45 (1994) 932
-
(1994)
Mol. Pharmacol.
, vol.45
, pp. 932
-
-
Sands, H.1
Gorey-Feret, L.J.2
Cocuzza, A.J.3
-
173
-
-
0007940905
-
Heterocyclic base modifications in nucleic acids and their applications in antisense oligonucleotides
-
Crooke S.T., and Lebleu B. (Eds), CRC Press, Boca Raton, Florida.
-
Sanghvi Y.S. Heterocyclic base modifications in nucleic acids and their applications in antisense oligonucleotides. In: Crooke S.T., and Lebleu B. (Eds). Antisense Research and Applications (1993), CRC Press, Boca Raton, Florida. 273
-
(1993)
Antisense Research and Applications
, pp. 273
-
-
Sanghvi, Y.S.1
-
174
-
-
0003847116
-
-
Sanghvi Y.S., and Cook P.D. (Eds), American Chemical Society, Washington, D.C.
-
In: Sanghvi Y.S., and Cook P.D. (Eds). "Carbohydrate Modifications in Antisense Research." (1994), American Chemical Society, Washington, D.C.
-
(1994)
"Carbohydrate Modifications in Antisense Research."
-
-
-
175
-
-
0027240213
-
Antisense oligonucleotides: Synthesis and biological evaluation of oligodeoxynucleotides containing modified pyrimidines
-
Sanghvi Y.S., Hoke G.D., Freier S.M., et al. Antisense oligonucleotides: Synthesis and biological evaluation of oligodeoxynucleotides containing modified pyrimidines. Nucleic Acids Res. 21 (1993) 3197
-
(1993)
Nucleic Acids Res.
, vol.21
, pp. 3197
-
-
Sanghvi, Y.S.1
Hoke, G.D.2
Freier, S.M.3
-
176
-
-
12044257509
-
Functional group substitutions as probes of hydrogen bonding between GA mismatches in RNA internal loops
-
Santa Lucia J., Kierzek R., and Turner D.H. Functional group substitutions as probes of hydrogen bonding between GA mismatches in RNA internal loops. J. Am. Chem. Soc. 113 (1991) 4314
-
(1991)
J. Am. Chem. Soc.
, vol.113
, pp. 4314
-
-
Santa Lucia, J.1
Kierzek, R.2
Turner, D.H.3
-
177
-
-
0001476029
-
Inhibition of acquired immunodeficiency syndrome virus by oligodeoxynucleoside methylphosphonates
-
Sarin P.S., Agrawal S., and Civeira M.P. Inhibition of acquired immunodeficiency syndrome virus by oligodeoxynucleoside methylphosphonates. Proc. Natl. Acad. Sci. U.S.A. 85 (1988) 7448
-
(1988)
Proc. Natl. Acad. Sci. U.S.A.
, vol.85
, pp. 7448
-
-
Sarin, P.S.1
Agrawal, S.2
Civeira, M.P.3
-
178
-
-
0025248128
-
Microinjected oligonucleotides complementary to the α-sarcin loop of 28 S RNA abolish protein synthesis in Xenopus oocytes
-
Saxena S.K., and Ackerman E.J. Microinjected oligonucleotides complementary to the α-sarcin loop of 28 S RNA abolish protein synthesis in Xenopus oocytes. J. Biol. Chem. 265 (1990) 3263
-
(1990)
J. Biol. Chem.
, vol.265
, pp. 3263
-
-
Saxena, S.K.1
Ackerman, E.J.2
-
180
-
-
0028037219
-
Antisense oligonucleotides adsorbed to polyalkylcyanoacrylate nanoparticles specifically inhibit mutated Ha-ras mediated cell proliferation and tumorigenicity in nude mice
-
Schwab G., Chavany C., Duroux I., et al. Antisense oligonucleotides adsorbed to polyalkylcyanoacrylate nanoparticles specifically inhibit mutated Ha-ras mediated cell proliferation and tumorigenicity in nude mice. Proc. Natl. Acad. Sci. U.S.A. 91 (1994) 10460
-
(1994)
Proc. Natl. Acad. Sci. U.S.A.
, vol.91
, pp. 10460
-
-
Schwab, G.1
Chavany, C.2
Duroux, I.3
-
181
-
-
0024354250
-
6-methylated 7-dazaadenine and 8-aza-7-deazaadenine: Solid phase synthesis of oligodeoxyribonucleotides and properties of self-complementary duplexes
-
6-methylated 7-dazaadenine and 8-aza-7-deazaadenine: Solid phase synthesis of oligodeoxyribonucleotides and properties of self-complementary duplexes. Helv. Chim. Acta 72 (1989) 868
-
(1989)
Helv. Chim. Acta
, vol.72
, pp. 868
-
-
Seela, F.1
Kaiser, K.2
Bindig, U.3
-
182
-
-
0028827079
-
Oligonucleotide duplex stability controlled by the 7-substituents of 7-deazaguanine bases
-
Seela F., Ramzaeva N., and Chen Y. Oligonucleotide duplex stability controlled by the 7-substituents of 7-deazaguanine bases. Bioorg. Med. Chem. Lett. 5 (1995) 3049
-
(1995)
Bioorg. Med. Chem. Lett.
, vol.5
, pp. 3049
-
-
Seela, F.1
Ramzaeva, N.2
Chen, Y.3
-
183
-
-
0026641052
-
Antisense c-myb oligonucleotides inhibit intimal arterial smooth muscle cell accumulation in vivo
-
Simons M., Edelman E.R., and De Keyser J.-L. Antisense c-myb oligonucleotides inhibit intimal arterial smooth muscle cell accumulation in vivo. Nature (London) 359 (1992) 67
-
(1992)
Nature (London)
, vol.359
, pp. 67
-
-
Simons, M.1
Edelman, E.R.2
De Keyser, J.-L.3
-
184
-
-
0028246149
-
Antisense proliferating cell nuclear antigen oligonucleotides inhibit intimal hyperplasia in a rat carotid artery injury model
-
Simons M., Edelman E.R., and Rosenberg R.D. Antisense proliferating cell nuclear antigen oligonucleotides inhibit intimal hyperplasia in a rat carotid artery injury model. J. Clin. Invest. 9 (1994) 2351
-
(1994)
J. Clin. Invest.
, vol.9
, pp. 2351
-
-
Simons, M.1
Edelman, E.R.2
Rosenberg, R.D.3
-
186
-
-
0028267577
-
Ventral tegmental area (VTA) injections of tyrosine hydroxylase phosphorothioate antisense oligonucleotide suppress operant behavior in rats
-
Skutella T., Probst J.C., Jirikowski G.F., et al. Ventral tegmental area (VTA) injections of tyrosine hydroxylase phosphorothioate antisense oligonucleotide suppress operant behavior in rats. Neurosci. Lett. 167 (1994) 55
-
(1994)
Neurosci. Lett.
, vol.167
, pp. 55
-
-
Skutella, T.1
Probst, J.C.2
Jirikowski, G.F.3
-
187
-
-
0001508918
-
Antiviral effect of an oligo(nucleoside methylphosphonate) complementary to the splice junction of herpes simplex virus type 1 immediate early pre-mRNAs 4 and 5
-
Smith C.C., Aurelian L., Reddy M.P., et al. Antiviral effect of an oligo(nucleoside methylphosphonate) complementary to the splice junction of herpes simplex virus type 1 immediate early pre-mRNAs 4 and 5. Proc. Natl. Acad. Sci. U.S.A. 83 (1986) 2787
-
(1986)
Proc. Natl. Acad. Sci. U.S.A.
, vol.83
, pp. 2787
-
-
Smith, C.C.1
Aurelian, L.2
Reddy, M.P.3
-
188
-
-
0002693117
-
2-O-Alkyloligoribonucleotides
-
Crooke S.T., and Lebleu B. (Eds), CRC Press, Boca Raton, Florida.
-
Sproat B.S., and Lamond A.I. 2-O-Alkyloligoribonucleotides. In: Crooke S.T., and Lebleu B. (Eds). Antisense Research and Applications (1993), CRC Press, Boca Raton, Florida. 351
-
(1993)
Antisense Research and Applications
, pp. 351
-
-
Sproat, B.S.1
Lamond, A.I.2
-
189
-
-
0024519705
-
Highly efficient chemical synthesis of 2-0-methyloligoribonucleotides and tetrabiotinylated derivatives; novel probes that are resistant to degradation by RNA or DNA specific nucleases
-
Sproat B.S., Lamond A.L., Beijer B., et al. Highly efficient chemical synthesis of 2-0-methyloligoribonucleotides and tetrabiotinylated derivatives; novel probes that are resistant to degradation by RNA or DNA specific nucleases. Nucleic Acids Res. 17 (1989) 3373
-
(1989)
Nucleic Acids Res.
, vol.17
, pp. 3373
-
-
Sproat, B.S.1
Lamond, A.L.2
Beijer, B.3
-
190
-
-
0025963388
-
New synthetic routes to synthons suitable for 2-O-aliyloligoribonucleotide assembly
-
Sproat B.S., Iribarren A.M., et al. New synthetic routes to synthons suitable for 2-O-aliyloligoribonucleotide assembly. Nucleic Acids Res. 19 (1991) 733
-
(1991)
Nucleic Acids Res.
, vol.19
, pp. 733
-
-
Sproat, B.S.1
Iribarren, A.M.2
-
191
-
-
0029086725
-
Characterization of binding sites, extent of binding and drug interactions of oligonucleotides with albumin
-
Srinivasan S.K., Tewary H.K., and Iversen P.L. Characterization of binding sites, extent of binding and drug interactions of oligonucleotides with albumin. Antisense Res. Dev. 5 (1995) 131
-
(1995)
Antisense Res. Dev.
, vol.5
, pp. 131
-
-
Srinivasan, S.K.1
Tewary, H.K.2
Iversen, P.L.3
-
192
-
-
0027376439
-
Antisense oligonucleotides as therapeutic agents. Is the bullet really magic?
-
Stein C.A., and Cheng Y.-C. Antisense oligonucleotides as therapeutic agents. Is the bullet really magic?. Science 261 (1993) 1004
-
(1993)
Science
, vol.261
, pp. 1004
-
-
Stein, C.A.1
Cheng, Y.-C.2
-
193
-
-
0003082218
-
Phosphorothioate oligodeoxynucleotide analogues.
-
Cohen J.S. (Ed), CRC Press, Boca Raton, Florida.
-
Stein C.A., and Cohen J.S. Phosphorothioate oligodeoxynucleotide analogues. In: Cohen J.S. (Ed). "Oligodeoxynucleotides: Antisense Inhibitors of Gene Expression" (1989), CRC Press, Boca Raton, Florida. 97
-
(1989)
"Oligodeoxynucleotides: Antisense Inhibitors of Gene Expression"
, pp. 97
-
-
Stein, C.A.1
Cohen, J.S.2
-
194
-
-
0026058794
-
Phosphorothioate oligodeoxycytidine interferes with binding of HIV-1 with gpl20 to CD4
-
Stein C.A., Neckers L.M., Nair B.C., et al. Phosphorothioate oligodeoxycytidine interferes with binding of HIV-1 with gpl20 to CD4. J. AIDS 4 (1991) 686
-
(1991)
J. AIDS
, vol.4
, pp. 686
-
-
Stein, C.A.1
Neckers, L.M.2
Nair, B.C.3
-
195
-
-
0027987972
-
Blocking of heart allograft rejection by intercellular adhesion molecule-1 antisense oligonucleotides alone or in combination with other immunosuppressive modalities
-
Stepkowski S.M., Tu Y., Condon T.P., et al. Blocking of heart allograft rejection by intercellular adhesion molecule-1 antisense oligonucleotides alone or in combination with other immunosuppressive modalities. J. Immunol. 10 (1994) 5336
-
(1994)
J. Immunol.
, vol.10
, pp. 5336
-
-
Stepkowski, S.M.1
Tu, Y.2
Condon, T.P.3
-
196
-
-
0028278976
-
c-fos antisense in rostral ventral medulla reduces arterial blood pressure
-
Suzuki S., Pilowsky P., and Minson J. c-fos antisense in rostral ventral medulla reduces arterial blood pressure. J. Physiol. (London) R1418 (1994)
-
(1994)
J. Physiol. (London)
, vol.R1418
-
-
Suzuki, S.1
Pilowsky, P.2
Minson, J.3
-
197
-
-
0029146596
-
Uptake, intracellular distribution, and stability of oligodeoxynucleotide phosphorothioate by
-
Tao L.-F., Marz K.A., Wongwit W., et al. Uptake, intracellular distribution, and stability of oligodeoxynucleotide phosphorothioate by. Schistosoma mansoni. Antisense Res. Dev. 5 (1995) 123
-
(1995)
Schistosoma mansoni. Antisense Res. Dev.
, vol.5
, pp. 123
-
-
Tao, L.-F.1
Marz, K.A.2
Wongwit, W.3
-
198
-
-
0027756125
-
Pharmacokinetics, biodistribution and stability of capped oligodeoxynucleotide phosphorothioates in mice
-
Temsamani J., Tang J.-Y., Padmapriya A., et al. Pharmacokinetics, biodistribution and stability of capped oligodeoxynucleotide phosphorothioates in mice. Antisense Res. Dev. 3 (1993) 277
-
(1993)
Antisense Res. Dev.
, vol.3
, pp. 277
-
-
Temsamani, J.1
Tang, J.-Y.2
Padmapriya, A.3
-
199
-
-
0025160649
-
Current concepts in quantitative molecular hybridization
-
Thompson J.D., and Gillespie D. Current concepts in quantitative molecular hybridization. Clin. Biochem. 23 (1990) 261-266
-
(1990)
Clin. Biochem.
, vol.23
, pp. 261-266
-
-
Thompson, J.D.1
Gillespie, D.2
-
200
-
-
1542532735
-
Oligodeoxynucleotides covalently linked to intercalating and reactive substances: Synthesis, characterization and physicochemical studies
-
Cohen J.S. (Ed), CRC Press, Boca Raton, Florida.
-
Thuong N.T., Asseline U., and Monteney-Garestier T. Oligodeoxynucleotides covalently linked to intercalating and reactive substances: Synthesis, characterization and physicochemical studies. In: Cohen J.S. (Ed). Oligodeoxynucleotides: Antisense Inhibitors of Gene Expression (1989), CRC Press, Boca Raton, Florida. 25
-
(1989)
Oligodeoxynucleotides: Antisense Inhibitors of Gene Expression
, pp. 25
-
-
Thuong, N.T.1
Asseline, U.2
Monteney-Garestier, T.3
-
201
-
-
0027998495
-
Sequence-specific impairment of learning by c-jun antisense oligonucleotides
-
Tischmeyer W., Grimm R., Schicknick H., et al. Sequence-specific impairment of learning by c-jun antisense oligonucleotides. NeuroReport 5 (1994) 1501
-
(1994)
NeuroReport
, vol.5
, pp. 1501
-
-
Tischmeyer, W.1
Grimm, R.2
Schicknick, H.3
-
202
-
-
0342432406
-
Nucleic acid analogs with targeted delivery at chemotherapeutic agents
-
Cheng Y.C., Gox B., and Minkoff M. (Eds), Raven Press, New York
-
Ts'o P.O.P., Miller P.S., and Greene J.J. Nucleic acid analogs with targeted delivery at chemotherapeutic agents. In: Cheng Y.C., Gox B., and Minkoff M. (Eds). Development of Target-Oriented Anticancer Drugs (1983), Raven Press, New York 189
-
(1983)
Development of Target-Oriented Anticancer Drugs
, pp. 189
-
-
Ts'o, P.O.P.1
Miller, P.S.2
Greene, J.J.3
-
203
-
-
0024826733
-
Modulation of drug resistance in a daunorubicin resistant subline with oligonucleoside methylphosphonates
-
Vasanthakumar G., and Ahmed N.K. Modulation of drug resistance in a daunorubicin resistant subline with oligonucleoside methylphosphonates. Cancer Commun. 1 (1989) 225
-
(1989)
Cancer Commun.
, vol.1
, pp. 225
-
-
Vasanthakumar, G.1
Ahmed, N.K.2
-
204
-
-
0025834035
-
Inhibition of HIV-LTR gene expression by oligonucleotides targeted to the TAR element
-
Vickers T., Baker B.F., Cook P.D., et al. Inhibition of HIV-LTR gene expression by oligonucleotides targeted to the TAR element. Nucleic Acids Res. 19 (1991) 3359
-
(1991)
Nucleic Acids Res.
, vol.19
, pp. 3359
-
-
Vickers, T.1
Baker, B.F.2
Cook, P.D.3
-
206
-
-
0027246678
-
Antisense gene inhibition by oligonucleotides containing C-5 propyne pyrimidines
-
Wagner R.W., Matteucci M.D., Lewis J.G., et al. Antisense gene inhibition by oligonucleotides containing C-5 propyne pyrimidines. Science 260 (1993) 1510
-
(1993)
Science
, vol.260
, pp. 1510
-
-
Wagner, R.W.1
Matteucci, M.D.2
Lewis, J.G.3
-
207
-
-
0027450169
-
Modulation of anxiety and neuropeptide Y-Y1 receptors by antisense oligodeoxynucleotides
-
Wahlestedt C., Pich E.M., Koob G.F., et al. Modulation of anxiety and neuropeptide Y-Y1 receptors by antisense oligodeoxynucleotides. Science 259 (1993) 528
-
(1993)
Science
, vol.259
, pp. 528
-
-
Wahlestedt, C.1
Pich, E.M.2
Koob, G.F.3
-
208
-
-
0024041180
-
Role of RNase H in hybrid-arrested translation by antisense oligonucleotides
-
Walder R.Y., and Walder J.A. Role of RNase H in hybrid-arrested translation by antisense oligonucleotides. Proc. Natl. Acad. Sci. U.S.A. 85 (1988) 5011
-
(1988)
Proc. Natl. Acad. Sci. U.S.A.
, vol.85
, pp. 5011
-
-
Walder, R.Y.1
Walder, J.A.2
-
209
-
-
0025306161
-
Inhibition of protein synthesis by anti-5.8S rRNA oligodeoxyribonucleotides
-
Walker K., Elela S.A., and Nazar R.N. Inhibition of protein synthesis by anti-5.8S rRNA oligodeoxyribonucleotides. J. Biol. Chem. 265 (1990) 2428
-
(1990)
J. Biol. Chem.
, vol.265
, pp. 2428
-
-
Walker, K.1
Elela, S.A.2
Nazar, R.N.3
-
210
-
-
0028924955
-
Delivery of antisense oligodeoxyribonucleotides against the human epidermal growth factor receptor into cultured KB cells with liposomes conjugated to folate via polyethylene glycol
-
Wang S., Lee R.J., Cauchon G., et al. Delivery of antisense oligodeoxyribonucleotides against the human epidermal growth factor receptor into cultured KB cells with liposomes conjugated to folate via polyethylene glycol. Proc. Natl. Acad. Sci. U.S.A. 92 (1995) 3318
-
(1995)
Proc. Natl. Acad. Sci. U.S.A.
, vol.92
, pp. 3318
-
-
Wang, S.1
Lee, R.J.2
Cauchon, G.3
-
211
-
-
0038497542
-
Molecular structure of nucleic acids: A structure for deoxyribose nucleic acid
-
Watson J.D., and Crick F.H.C. Molecular structure of nucleic acids: A structure for deoxyribose nucleic acid. Nature (London) 171 (1953) 737
-
(1953)
Nature (London)
, vol.171
, pp. 737
-
-
Watson, J.D.1
Crick, F.H.C.2
-
213
-
-
0024517255
-
Inhibition of expression of SV40 virus large T-antigen by antisense oligodeoxyribonucleotides
-
Westerman P., Gross B., and Hoinkis G. Inhibition of expression of SV40 virus large T-antigen by antisense oligodeoxyribonucleotides. Biomed. Biochem. Acta 48 (1989) 85
-
(1989)
Biomed. Biochem. Acta
, vol.48
, pp. 85
-
-
Westerman, P.1
Gross, B.2
Hoinkis, G.3
-
214
-
-
0026295042
-
In vivo modulation of N-myc expression by continuous perfusion with an antisense oligonucleotide.
-
Whitesell L., Rosolen A., and Neckers L.M. In vivo modulation of N-myc expression by continuous perfusion with an antisense oligonucleotide. Antisense Res. Dev. 1 (1991) 343
-
(1991)
Antisense Res. Dev.
, vol.1
, pp. 343
-
-
Whitesell, L.1
Rosolen, A.2
Neckers, L.M.3
-
215
-
-
0022780091
-
Oligodeoxynucleotide stability in subcellular extracts and culture media
-
Wickström E. Oligodeoxynucleotide stability in subcellular extracts and culture media. J. Biochem. Biophys. Methods 13 (1986) 97
-
(1986)
J. Biochem. Biophys. Methods
, vol.13
, pp. 97
-
-
Wickström, E.1
-
216
-
-
0024565153
-
Anti-c-myc DNA increases differentiation and decreases colony formation by HL-60 cells in vitro.
-
Wickström E.L., Bacon T.A., Gonzalez A., et al. Anti-c-myc DNA increases differentiation and decreases colony formation by HL-60 cells in vitro. Cell Dev. Biol. 25 (1989) 297
-
(1989)
Cell Dev. Biol.
, vol.25
, pp. 297
-
-
Wickström, E.L.1
Bacon, T.A.2
Gonzalez, A.3
-
217
-
-
0028151678
-
The effect of c-fos antisense in the formalin-paw test
-
Woodburn V.L., Hunter J.C., Durieux C., Poat J.A., and Hughes J. The effect of c-fos antisense in the formalin-paw test. Regul. Pept. 54 (1994) 327
-
(1994)
Regul. Pept.
, vol.54
, pp. 327
-
-
Woodburn, V.L.1
Hunter, J.C.2
Durieux, C.3
Poat, J.A.4
Hughes, J.5
-
218
-
-
0027983025
-
Combinatorially selected guanosine-quartet structure is a potent inhibitor of human immunodeficiency virus envelope-mediated cell fusion
-
Wyatt J.R., Vickers T.A., Roberson J.L., et al. Combinatorially selected guanosine-quartet structure is a potent inhibitor of human immunodeficiency virus envelope-mediated cell fusion. Proc. Natl. Acad. Sci. U.S.A. 91 (1994) 1356
-
(1994)
Proc. Natl. Acad. Sci. U.S.A.
, vol.91
, pp. 1356
-
-
Wyatt, J.R.1
Vickers, T.A.2
Roberson, J.L.3
-
219
-
-
0041582974
-
Inhibition of Rous sarcoma virus replication and cell transformation by a specific oligodeoxynucleotide
-
Zamecnik P.C., and Stephenson M.L. Inhibition of Rous sarcoma virus replication and cell transformation by a specific oligodeoxynucleotide. Proc. Natl. Acad. Sci. U.S.A. 75 (1978) 280
-
(1978)
Proc. Natl. Acad. Sci. U.S.A.
, vol.75
, pp. 280
-
-
Zamecnik, P.C.1
Stephenson, M.L.2
-
220
-
-
0001477721
-
Inhibition of replication and expression of human T-cell lymphotropic virus type III in cultured cells by exogenous synthetic oligonucleotides complementary to viral RNA
-
Zamecnik P.C., Goodchild J., Taguchi Y., et al. Inhibition of replication and expression of human T-cell lymphotropic virus type III in cultured cells by exogenous synthetic oligonucleotides complementary to viral RNA. Proc. Natl. Acad. Sci. U.S.A. 83 (1986) 4143
-
(1986)
Proc. Natl. Acad. Sci. U.S.A.
, vol.83
, pp. 4143
-
-
Zamecnik, P.C.1
Goodchild, J.2
Taguchi, Y.3
-
221
-
-
0023507398
-
Selective inhibition of the cytopathic effect of type A influenza viruses by oligodeoxynucleotides covalently linked to an intercalating agent
-
Zerial A., Thuong N.T., and Helene C. Selective inhibition of the cytopathic effect of type A influenza viruses by oligodeoxynucleotides covalently linked to an intercalating agent. Nucleic Acids Res. 15 (1987) 9909
-
(1987)
Nucleic Acids Res.
, vol.15
, pp. 9909
-
-
Zerial, A.1
Thuong, N.T.2
Helene, C.3
-
222
-
-
0027490804
-
2 receptors: Behavioral correlates
-
2 receptors: Behavioral correlates. Neurosci. Lett. 161 223 (1993) 4947
-
(1993)
Neurosci. Lett.
, vol.161
, Issue.223
, pp. 4947
-
-
Zhang, M.1
Creese, I.2
-
223
-
-
0029127845
-
Pharmacokinetics of an anti-human immunodeficiency virus antisense oligodeoxynucleotide phosphorothioate (GEM 91) in HIV-infected subjects
-
Zhang R., Yan J., Shahinian H., et al. Pharmacokinetics of an anti-human immunodeficiency virus antisense oligodeoxynucleotide phosphorothioate (GEM 91) in HIV-infected subjects. Clin. Pharmacol. Ther. 58 (1995) 44
-
(1995)
Clin. Pharmacol. Ther.
, vol.58
, pp. 44
-
-
Zhang, R.1
Yan, J.2
Shahinian, H.3
-
224
-
-
0029002066
-
In vivo stability and disposition of a self-stabilized oligodeoxynucleotide phosphorothioate in rats
-
Zhang R., Lu Z., Zhang X., et al. In vivo stability and disposition of a self-stabilized oligodeoxynucleotide phosphorothioate in rats. Clin. Chem. (Winston-Salem, N.C.) 41 (1995) 836
-
(1995)
Clin. Chem. (Winston-Salem, N.C.)
, vol.41
, pp. 836
-
-
Zhang, R.1
Lu, Z.2
Zhang, X.3
-
225
-
-
0028170936
-
1 dopamine receptor-mediated behaviors in normal mice and in mice lesioned with 6-hydroxydopamine
-
1 dopamine receptor-mediated behaviors in normal mice and in mice lesioned with 6-hydroxydopamine. J. Pharmacol. Exp. Ther. 271 (1994) 1462
-
(1994)
J. Pharmacol. Exp. Ther.
, vol.271
, pp. 1462
-
-
Zhang, S.-P.1
Zhou, L.-W.2
Weiss, B.3
-
226
-
-
0029123285
-
Syntheses and properties of novel thiono triester modified antisense oligodeoxynucleotide phosphorothioates
-
Zhang Z., Tang J.X., and Tang J.Y. Syntheses and properties of novel thiono triester modified antisense oligodeoxynucleotide phosphorothioates. Bioorg. Med. Chem. Lett. 5 (1995) 1735
-
(1995)
Bioorg. Med. Chem. Lett.
, vol.5
, pp. 1735
-
-
Zhang, Z.1
Tang, J.X.2
Tang, J.Y.3
-
227
-
-
0343455224
-
Specific inhibition of cell-surface T-cell receptor expression by antisense oligodeoxynucleotides and its effect on the production of an antigen-specific regulatory T-cell factor
-
Zheng H., Sahai B.M., Kilgannon P., et al. Specific inhibition of cell-surface T-cell receptor expression by antisense oligodeoxynucleotides and its effect on the production of an antigen-specific regulatory T-cell factor. Proc. Natl. Acad. Sci. U.S.A. 86 (1989) 3758
-
(1989)
Proc. Natl. Acad. Sci. U.S.A.
, vol.86
, pp. 3758
-
-
Zheng, H.1
Sahai, B.M.2
Kilgannon, P.3
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