Enteral nutrition with supplemented arginine, glutamine, RNA, and ω-3 fatty acids

Current Opinion in Critical Care

Volumn 4, Issue 4, 1998, Pages 263-268

  Gianotti, Luca ^a   Gentilini, Oreste ^a   Braga, Marco ^a  

^a SAN RAFFAELE HOSPITAL   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0001781307     PISSN: 10705295     EISSN: None     Source Type: Journal    
DOI: 10.1097/00075198-199808000-00010     Document Type: Article

References (67)

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50. Kemen M, Senkal M, Homann HH, Mumme A, Dauphin A-K, Baier J, Windeler J, Neumann H, Zumtobel V: Early postoperative enteral nutrition with arginine-omega 3 fatty acids and ribonucleic acid-supplemented diet versus placebo in cancer patients: an immunologic evaluation of Impact. Crit Care Med 1995, 23:652-659.
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53. Moore FA, Moore EE, Kudsk KA, Brown RO, Bower RH, Koruma MJ, Baker CC, Barbul A: Clinical benefits of an immune-enhancing diet for early postinjury enteral feeding. J Trauma 1994, 37:607-615.
54. Bower RH, Cerra FB, Bershadsky B, Licari JJ, Hoyt DB, Van Buren CT, Rothkopt MM, Daly JM, Adelsberg BR: Early entera administration of a formula (Impact) supplemented with arginine, nucleotides and fish oil in intensive care unit patients: results of a multicenter, prospective, randomized clinical trial. Crit Care Med 1995, 23:436-449.
55. Daly JM, Weintraub FN, Shou J, Rosato EF, Lucia M: Enteral nutrition during multimodality therapy in upper gastrointestinal cancer patients. Ann Surg 1995, 221:327-338.
56. Kudsk KA, Minard G, Croce MA, Brown RO, Lowrey TS, Prichard FE, Dickenson RN, Fabian TC: A randomized trial of isonitrogenous enteral diets after severe trauma: an immuno-enhancing diet reduces septic complications. Ann Surg 1996, 224:531-543.
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60. Gianotti L, Braga M, Vignali A, Balzano G, Zerbi A, Bisagni P, Di Carlo V. Effect of route of delivery and formulation of postoperative nutritional support in patients undergoing major operations for malignant neoplasms. Arch Surg 1997, 132:1222-1230. The largest published trial on the impact of early enteral immunonutrition on outcome in cancer surgical patients. The study reports good tolerance of enteral feeding and a reduction of severity of infection and length of stay in the immunonourished group.
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64. Gianotti L, Braga M, Vaiani R, Profili M, Socci C, Di Carlo V: Effect of composition of enteral solutions and timing of administration on outcome and bacterial translocation. Riv Ital Nutr Parenter Enteral 1996, 14:191-195.
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66. Braga M, Gianotti L, Cestari A, Vignali A, Pellegatta F, Dolci A, Di Carlo V: Gut function, immune and inflammatory responses in patients perioperatively fed with supplemented formulas. Arch Surg 1996, 131:1257-1265. The first clinical trial studying the effects of perioperative administration of immunonutrition. Intestinal oxygen metabolism and host response are studied by several sophisticated in vivo procedures.
67. Braga M, Gianotti L, Radaelli G, Vignali A, Mari G, Gentilini O, Di Carlo V: Perioperative immunonutrition: results of a randomized double-blind phase III trial in cancer patients. Ann Surg, in press.*