Proteolytic cleavage of phospholipase C-γ1 during apoptosis in Molt-4 cells

FASEB Journal

Volumn 14, Issue 9, 2000, Pages 1083-1092

  Bae, Sun Sik ^a   Perry, David K ^b   Oh, Yong Seok ^a   Choi, Jang Hyun ^a   Galadari, Sehamuddin H ^c   Ghayur, Tariq ^d   Ryu, Sung Ho ^a   Hannun, Yusuf A ^b   Suh, Pann Ghill ^a  

^a Pohang University of Science and Technology (POSTECH)   (South Korea)

^b MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^c UNITED ARAB EMIRATES UNIVERSITY   (United Arab Emirates)

^d BASF Bioresearch Corporation   (United States)

Author keywords

PLC 1; Proteolysis; Tyrosine phosphorylation

Indexed keywords

CASPASE; PHOSPHOLIPASE C;

APOPTOSIS; ARTICLE; CONTROLLED STUDY; ENZYME ANALYSIS; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

EID: 0001455392     PISSN: 08926638     EISSN: None     Source Type: Journal    
DOI: 10.1096/fasebj.14.9.1083     Document Type: Article

References (47)

1. Steller, H. (1995) Mechanisms and genes of cellular suicide. Science 267, 1445-1449
2. Ellis, H. M., and Horvitz, H. R. (1986) Genetic control of programmed cell death in the nematode C. elegans. Cell 44, 817-829
3. Yuan, J., Shaham, S., Ledoux, S., Ellis, H., and Horvitz, H. R. (1993) The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1 beta-converting enzyme. Cell 75, 641-652
4. Alnemri, E. S., Livingston, D. J., Nicholson, D. W., Salvesen, G., Thornberry, N. A., Wong, W. W., and Yuan, J. (1996) Human ICE/CED-3 protease nomenclature. Cell 87, 171
5. Cohen, G. M. (1997) Caspases: the executioners of apoptosis. Biochem. J. 326, 1-16
6. Salvesen, G. S., and Dixit, V. M. (1997) Caspases: Intracellular signaling by proteolysis. Cell 91, 443-446
7. Boldin M. P., Goncharov T. M., Goltsev Y. V., and Wallach D. (1996) Involvement of MACH, a novel MORTI/FADD-interacting protease, in Fas/APO-1-and TNF receptor-induced cell death. Cell 85, 803-815
8. Cryns, V., and Yuan, J. (1998) Proteases to die for. Genes Dev. 12, 1551-1570
9. Luo, X., Budihardjo, I., Zou, H., Slaughter, C., and Wang, X. (1998) Bid, a Bcl-2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors, Cell 94, 481-490
10. Shimizu, S., Narita, M., and Tsujimoto, Y. (1999) Bcl-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDAC. Nature (London) 399, 483-487
11. Zou, H., Henzel, W. J., Liu, X., Lutschg, A., and Wang, X. (1997) Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3. Cell 90, 405-413
12. Li, P., Nijhawan, D., Budihardjo, I., Srinivasula, S. M., Ahmad, M., Alnemri, E. S., and Wang, X. (1997) Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade. Cell 91, 479-489
13. Liu, X., Zou, H., Slaughter, C., and Wang, X. (1997) DFF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis. Cell 89, 175-184
14. Xue, D., and Horvitz, H. R. (1997) Caenorhabditis elegans CED-9 protein is a bifunctional cell-death inhibitor. Nature (London) 390, 305-308
15. Kothakota, S., Azuma, T., Reinhard, C., Klippel, A., Tang, J., Chu, K., McGarry, T. J., Kirschner, M. W., Koths, K., Kwiatkowski, D. J., and Williams, L. T. (1997) Caspase-3-generated fragment of gelsolin: effector of morphological change in apoptosis. Science 278, 294-298
16. Wen, L.-P., Fahrni, J. A., Troie, S., Guan, J.-L., Orth, K., and Rosen, G. D. (1997) Cleavage of focal adhesion kinase by caspases during apoptosis. J. Biol. Chem. 272, 26056-26061
17. Rudel, T., and Bokoch, G. M. (1997) Membrane and morphological changes in apoptotic cells regulated by caspase-mediated activation of PAK2. Science 276, 1571-1574
18. Jarpe, M. B., Widmann, C., Knall, C., Schlesinger, T. R., Gibson, S., Yujiri, T., Fanger, G. R., Gelfand, E. W., and Johnson, G. L. (1998) Anti-apoptotic versus pro-apoptotic signal transduction: checkpoints and stop signs along the road to death. Oncogene 17, 1475-1482
19. Franke, T. F., Kaplan, D. R., and Cantley, L. C. (1997) PI3K: downstream AKTion blocks apoptosis. Cell 88, 435-437
20. Bae, Y. S., Cantley, L. G., Chen, C. S., Kim, S. R., Kwon, K. S., and Rhee, S. G. (1998) Activation of phospholipase C.-γ by phosphatidylinositol 3,4,5-trisphosphate. J. Biol. Chem. 273, 4465-4469
21. Rhee, S. G., Suh, P.-G., Ryu, S. H., and Lee, S. Y. (1989) Studies of inositol phospholipid-specific phospholipase C. Science 244, 546-550
22. Huang, P. S., Davis, L., Huber, H., Goodhart, P. J., Wegrzyn, R. E., Oliff, A., and Heimbrook, D. C. (1995) An SH3 domain is required for the mitogenic activity of microinjected phospholipase C-γ1. FEBS Lett. 358, 287-292
23. Chang, J. S., Noh, D. Y., Park, I. A., Kim, M. J., Song, H., Ryu, S. H., and Suh, P.-G. (1997) Overexpression of phospholipase C-γ1 in rat 3Y1 fibroblast cells leads to malignant transformation. Cancer Res. 57, 5465-5468
24. Bielawska, A., Crane, H. M., Loitta, D., Obeid, L. M., and Hannun, Y. H. (1993) Selectivity of ceramide-mediated biology. Lack of activity of erythro-dihydroceramide. J. Biol. Chem. 268, 26226-26232
25. Suh, P.-G., Ryu, S. H., Choi, W. C., Lee, K.-Y., and Rhee, S. G. (1988) Monoclonal antibodies to three phospholipase C isozymes from bovine brain. J. Biol. Chem. 263, 14497-14504
26. Harlow, E., and Lane, D. (1988) Antibodies: A Laboratory Manual, pp. 53-119, Cold Spring Harbor Laboratory, Cold Spring Harbor, New York
27. Talanian, R. V., Quinlan, C., Trautz, S., Hackett, M. C., Mankovich, J. A., Banach, D., Ghayur, T., Brady, K. D., and Wong, W. W. (1997) Substrate specificities of caspase family proteases. J. Biol. Chem. 272, 9677-9682
28. Zhang, J., Alter, N., Reed, J. C., Borner, C., Obeid, L. M., and Hannun, Y. A. (1996) Bcl-2 interrupts the ceramide-mediated pathway of cell death. Proc. Natl. Acad. Sci. USA 93, 5325-5328
29. Dietrich, A., Meister, M., Spicher, K., Schultz, G., Camps, M., and Gierschik, P. (1992) Expression, characterization and purification of soluble G-protein beta gamma dimers composed of defined subunits in baculovirus-infected insect cells. FEBS Lett. 313, 220-224
30. Perry, D. K., Smyth, M. J., Wang, H.-G., Reed, J. C., Duriez, P., Poirier, G. G., Obeid, L. M., and Hannun, Y. A. (1997) Bcl-2 acts upstream of the PARP protease and prevents its activation. Cell Death Differ. 4, 29-33
31. Ho, S. N., Hunt, H. D., Horton, R. M., Pullen, J. K., and Pease, L. R. (1989) Site-directed mutagenesis by overlap extension using the polymerase chain reaction. Gene (Amst.) 77, 51-59
32. Ruvolo, P. P., Deng, X., Carr, B. K., and May, W. S. (1998) A functional role for mitochondrial protein kinase Cα in Bcl-2 phosphorylation and suppression of apoptosis. J. Biol. Chem. 273, 25436-25442
33. Nagata, S. (1997) Apoptosis by death factor. Cell 88, 355-365
34. Yang, J., Liu, X., Bhalla, K., Kim, C. N., Ibrado, A. M., Cai, J., Peng, T.-I., Jones, D. P., and Wang, X. (1997) Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked. Science 275, 1129-1132
35. Thornberry, N. A., Rano, T. A., Peterson, E. P., Rasper, D. M., Timkey, T., Garcia-Calvo, M., Houtzager, V. M., Nordstrom, P. A., Roy, S., Vaillancourt, J. P., Chapman, K. T., and Nicholson, D. W. (1997) A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis. J. Biol. Chem. 272, 17907-17911
36. Oh, W. K., Yoo, J. C., Jo, D., Song, Y. H., Kim, M. G., Park, D. (1997) Cloning of a SH3 domain-containing proline-rich protein, p85SPR, and its localization in focal adhesion. Biochem. Biophys. Res. Commun. 235, 794-798
37. Noh, D.-Y., Shin, S. H., and Rhee, S. G. (1995) Phosphoinositide-specific phospholipase C and mitogenic signaling. Biochim. Biophys. Acta 1242, 99-114
38. Kim, H. K., Kim, J. W., Zilberstein, A., Margolis, B., Kim, J. G., Schlessinger, J., and Rhee, S. G. (1991) PDGF stimulation of inositol phospholipid hydrolysis requires PLC-γ1 phosphorylation on tyrosine residues 783 and 1254. Cell 65, 435-441
39. Widmann, C., Gibson, S., and Johnson, G. L. (1998) Caspase-dependent cleavage of signaling proteins during apoptosis. A turn-off mechanism for anti-apoptotic signals. J. Biol. Chem. 273, 7141-7147
40. Barkett, M., Xue, D., Horvitz, H. R., and Gilmore, T. D. (1997) Phosphorylation of IkB-α inhibits its cleavage by caspase CPP32 in vitro. J. Biol. Chem. 272, 29419-29422
41. Yang, L. J., Rhee, S. G., and Williamson, J. R. (1994) Epidermal growth factor-induced activation and translocation of phospholipase C-γ1 to the cytoskeleton in rat hepatocytes. J. Biol. Chem. 269, 7156-7162
42. Chandler, J. M., Cohen, G. M., MacFarlane, M. (1998) Different subcellular distribution of caspase-3 and caspase-7 following Fas-induced apoptosis in mouse liver. J. Biol. Chem. 273, 10815-10818
43. Fernald, A. W., Jones, G. A., and Carpenter, G. (1994) Limited proteolysis of phospholipase C-g1 indicates stable association of X and Y domains with enhanced catalytic activity. Biochem. J. 302, 503-509
44. Datta, S. R., Dudek, H., Tao, X., Masters, S., Fu, H., Gotoh, Y., and Greenberg, M. E. (1997) Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery. Cell 91, 231-241
45. Cardone, M. H., Roy, N., Steinnicke, H. R., Salvesen, G. S., Franke, T. F., Stanbridge, E., Frisch, S., and Reed, J. C. (1998) Regulation of cell death protease caspase-9 by phosphorylation. Science 282, 1318-1321
46. Cheng, E. H., Kirsch, D. G., Clem, R. J., Ravi, R., Kastan, M. B., Bedi, A., Ueno, K., and Hardwick, J. M. (1997) Conversion of Bcl-2 to a Bax-like death effector by caspases. Science 278, 1966-1968
47. Santoro, M. F., Annand, R. R., Robertson, M. M., Peng, Y.-W., Brady, M. J., Mankovich, J. A., Hackett, M. C., Ghayur, T., Walter, G., Wong, W. W., and Giegel, D. A. (1998) Regulation of protein phosphatase 2A activity by caspase-3 during apoptosis. J. Biol. Chem. 273, 13119-13128