The O-linked fucose glycosylation pathway. Identification and characterization of a uridine diphosphoglucose: Fucose-β1,3-glucosyltransferase activity from Chinese hamster ovary cells

Glycobiology

Volumn 9, Issue 7, 1999, Pages 679-687

  Moloney, Daniel J ^a   Haltiwanger, Robert S ^a  

^a STONY BROOK UNIVERSITY   (United States)

Author keywords

Chinese hamster ovary cells; Glucosyltransferase; Glycosyltransferases; O linked fucose

Indexed keywords

FUCOSE; GLUCOSE; GLUCOSYLTRANSFERASE; GLYCOCONJUGATE; HYDROXYL GROUP; MANGANESE; SERINE; THREONINE; URIDINE DIPHOSPHATE GLUCOSE;

ANIMAL CELL; ARTICLE; CARBOHYDRATE ANALYSIS; CHICKEN; CHO CELL; ENZYME ACTIVITY; ENZYME SPECIFICITY; GLYCOSYLATION; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; TIME;

ANIMALS; CARBOHYDRATE CONFORMATION; CELL LINE; CHICKENS; CHO CELLS; CRICETINAE; FEMALE; FUCOSE; GLUCOSYLTRANSFERASES; GLYCOSYLATION; HUMANS; HYDROGEN-ION CONCENTRATION; KINETICS; MICE; RATS; SUBSTRATE SPECIFICITY; TEMPERATURE; TISSUE DISTRIBUTION;

EID: 0032805976     PISSN: 09596658     EISSN: None     Source Type: Journal    
DOI: 10.1093/glycob/9.7.679     Document Type: Article

References (35)

1. Abmayr, S.M. and Workman, J.L. (1990) Preparation of nuclear and cytoplasmic extracts from mammalian cells. In Current Protocols in Molecular Biology. John Wiley and Sons, New York, pp. 12.1.1-12.1.9.
2. Amado, M., Almeida, R., Cameiro, F., Levery, S.B., Holmes, E.H., Nomoto, M., Hollingsworth, M.A., Hassan, H., Schwientek, T., Nielsen, P.A., Bennett, E.P. and Clausen, H. (1998) A family of human β3-galactosyltransferases - characterization of four members of a UDP-galactose:β-N-acetyl-glucosamine/βN-acetyl-galactosamine β-1,3-galactosyltransferase family. J. Biol. Chem., 273, 12770-12778.
3. Beug, H., von Kirchbach, A., Doderlein, G., Conscience, J.F. and Graf, T. (1979) Chicken hematopoietic cells transformed by seven strains of defective avian leukemia viruses display three distinct phenotypes of differentiation. Cell. 18, 375-390.
4. Beyer, T.A., Sadler, J.E., Rearick, J.I., Paulson, J.C. and Hill, R.L. (1981) Glycosyltransferases and their use in assessing oligosaccharide structure and structure -function relationships. Adv. Enzymol., 52, 23-175.
5. Bjoern, S., Foster, D.C., Thim, L., Wiberg, F.C., Christensen, M., Komiyama, Y. Pedersen, A.H. and Kisiel, W. (1991) Human plasma and recombinant factor VII: characterization of O-glycosylation at serine residues 52 and 60 and effects of site-directed mutagenesis of serine 52 to alanine. J. Biol. Chem., 266, 11051-11057.
6. Cummings, R.D. (1992) Synthesis of Asparagine-linked oligosaccharides: pathways, genetics and metabolic regulation. In Allen, H.J. and Kisailus, E.C. (eds.), Glycoconjugates: Composition, Structure and Function. Marcel Dekker, New York, pp. 333-360.
7. Dahms, N.M., Lobel, P. and Kornfeld, S. (1989) Mannose 6-phosphate receptors and lysosomal enzyme targeting. J. Biol. Chem., 264, 12115-12118.
8. Fleming, R.J., Purcell, K. and Artavanis-Tsakonas, S. (1997) The NOTCH receptor and its ligands. Trends Cell Biol., 7, 437-441.
9. Gohlke, M., Baude, G., Nuck, R., Grunow, D., Kannicht, C., Bringmann, P., Donner, P. and Reutter, W. (1996) O-Linked L-fucose is present in Desmodus rotundus salivary plasminogen activator. J. Biol. Chem., 271, 7381-7386.
10. Haltiwanger, R.S., Holt, G.D. and Hart, G.W. (1990) Enzymatic addition of O-GlcNAc to nuclear and cytoplasmic proteins. Identification of a uridine diphospho-N-acetylglucosamine:peptide β-N-acetylglucosaminyltransferase. J. Biol. Chem., 265, 2563-2568.
11. Harris, R.J., Leonard, C.K., Guzzetta, A.W. and Spellman, M.W. (1991) Tissue plasminogen activator has an O-linked fucose attached to threonine-61 in the epidermal growth factor domain. Biochemistry, 30, 2311-2314.
12. Harris, R.J., Ling, V.T. and Spellman, M.W. (1992) O-Linked fucose is present in the first epidermal growth factor domain of factor XII but protein C. J. Biol. Chem., 267, 5102-5107.
13. Harris, R.J. and Spellman, M.W. (1993) O-linked fucose and other post-translational modifications unique to EGF modules. Glycobiology. 3, 219-224.
14. Harris, R.J., Van Halbeek, H., Glushka, J., Basa, L.J., Ling, V.T., Smith, K.J. and Spellman, M.W. (1993) Identification and structural analysis of the tetrasaccharide NeuAcα (2→6)Galβ (1→4)GlcNAcβ (1→3)Fucα1→O-linked to serine 61 of human factor IX. Biochemistry, 32, 6539-6547.
15. Hebert, D.N., Foellmer, B. and Helenius, A. (1995) Glucose trimming and reglucosylation determine glycoprotein association with calnexin in the endoplasmic reticulum. Cell, 81, 425-433.
16. Hirschberg, C.B. and Snider, M.D. (1987) Topography of glycosylation in the rough endoplasmic reticulum and Golgi apparatus. Annu. Rev. Biochem., 56, 63-87.
17. Holt, G.D. and Hart, G.W. (1986) The subcellular distribution of terminal N-acetylglucosamine moieties. Localization of a novel protein-saccharide linkage. O-linked GlcNAc. J. Biol. Chem., 261, 8049-8057.
18. Jensen, C.H., Krogh, T.N., Hojrup, P., Clausen, P.R., Skjodt, K., Larsson, L.I., Enghild, J.J. and Teisner, B. (1994) Protein structure of fetal antigen 1 (FA1). A novel circulating human epidermal growth factor-like protein expressed in neuroendocrine tumors and its relation to the gene products of dlk and pG2. Eur. J. Biochem., 225, 83-92.
19. Kentzer, E.J., Buko, A.M., Menon, G. and Sarin, V.K. (1990) Carbohydrate composition and presence of a fucose-protein linkage in recombinant human pro-urokinase. Biochem. Biophys. Res. Commun., 171, 401-406.
20. Kundu, S.K. (1992) Glycolipids: structure, synthesis, functions. In Allen, H.J. and Kisailus, E.C. (eds.). Glycoconjugates: Composition, Structure and Function. Marcel Dekker, New York, pp. 203-262.
21. Lang, L., Reitman, M.L., Tang, J., Roberts, R.M. and Kornfeld, S. (1984) Lysosomal enzyme phosphorylation. Recognition of a protein-dependent determinant allows specific phosphorylation of oligosaccharides present on lysosomal enzymes. J. Biol. Chem., 259, 14663-14671.
22. McEver, R.P, Moore, K.L. and Cummings, R.D. (1995) Leukocyte trafficking mediated by selectin-carbohydrate interactions. J. Biol. Chem., 270, 11025-11028.
23. Moloney, D.J. and Haltiwanger, R.S. (1998) O-Linked carbohydrate modifications on the epidermal growth factor-like modules of mammalian notch. Glycobiology, 8, 1105 (abstract).
24. Moloney, D.J., Lin, A.I. and Haltiwanger, R.S. (1997) The O-linked fucose glycosylation pathway: evidence for protein specific elongation of O-linked fucose in Chinese hamster ovary cells. J. Biol. Chem., 272, 19046-19050.
25. Nishimura, H., Takao, T., Hase, S., Shimonishi, Y. and Iwanaga, S. (1992) Human factor IX has a tetrasaccharide O-glycosidically linked to serine 61 through the fucose residue. J. Biol Chem., 267, 17520-17525.
26. Pitcher, J., Smythe, C. and Cohen, P. (1988) Glycogenin is the priming glucosyl-transferase required for the initiation of glycogen biogenesis in rabbit skeletal muscle. Eur. J. Biochem., 176, 391-395.
27. Rebay, I., Fleming, R.J., Fehon, R.G., Cherbas, L., Cherbas, P. and Artavanis-Tsakonas, S. (1991) Specific EGF repeats of notch mediate interactions with delta and serrate: implications for notch as a multifunctional receptor Cell, 67, 687-699.
28. Roth, J. (1997) Topology of glycosylation in the Golgi apparatus. In Berger, E.G. and Roth, J. (eds), The Golgi Apparatus. Birkhauser Verlag, Boston, pp. 131-162.
29. Smith, E.L., Hill, R.L., Lehman, I.R., Lefkowitz, R.J., Handler, P., and White, A. (1983) Principles of Biochemistry: Mammalian Biochemistry. McGraw-Hill, New York.
30. Smith, P.L. and Baenziger, J.U. (1988) A pituitary N-acetylgalactosamine transferase that specifically recognizes glycoprotein hormones. Science, 242, 930-933.
31. Smythe, C, Caudwell, F.B., Ferguson, M. and Cohen, P. (1988) Isolation and structural analysis of a peptide containing the novel tyrosyl-glucose linkage in glycogenin. EMBO J., 7, 2681-2686.
32. Stanley, P., and Siminovitch, L. (1977) Complementation between mutants of CHO cells resistant to a variety of plant lectins. Somatic Cell Genet., 3, 391-405.
33. Varki, A. (1993) Biological roles of oligosaccharides: all of the theories are correct. Glycobiology, 3, 97-130.
34. Wang, Y. and Spellman, M.W. (1998) Purification and characterization of a GDP-fucose: polypeptide fucosyltransferase from Chinese hamster ovary cells. J. Biol. Chem.. 273, 8112-8118.
35. Wang, Y., Lee, G.F., Kelley, R.F. and Spellman, M.W. (1996) Identification of a GDP-L-fucose: polypeptide fucosyltransferase and enzymatic addition of O-linked fucose to EGF domains. Glycobiology. 6, 837-842.