Lack of an effect of breast cancer resistance protein (BCRP/ABCG2) overexpression on methotrexate polyglutamate export and folate accumulation in a human breast cancer cell line

Biochemical Pharmacology

Volumn 69, Issue 1, 2005, Pages 123-132

  Rhee, Myung S ^a   Schneider, Erasmus ^a,b  

^a WADSWORTH CENTER   (United States)

^b STATE UNIVERSITY OF NEW YORK   (United States)

Author keywords

Breast cancer resistance protein; Drug resistance; Folate metabolism; Methotrexate; Polyglutamylation

Indexed keywords

BREAST CANCER RESISTANCE PROTEIN; FOLIC ACID; METHOTREXATE; METHOTREXATE POLYGLUTAMATE; PTEROPTIN; THYMIDYLATE SYNTHASE;

ARTICLE; BREAST CANCER; CELL LINE; CONTROLLED STUDY; DRUG ACCUMULATION; DRUG METABOLISM; DRUG TRANSPORT; ENZYME INHIBITION; HUMAN; HUMAN CELL; MUTATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION;

ATP-BINDING CASSETTE TRANSPORTERS; BREAST NEOPLASMS; CELL LINE, TUMOR; DOSE-RESPONSE RELATIONSHIP, DRUG; FOLIC ACID; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; METHOTREXATE; NEOPLASM PROTEINS; POLYGLUTAMIC ACID;

EID: 9944248649     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2004.09.007     Document Type: Article

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