Receptor-mediated endothelial cell dysfunction in diabetic vasculopathy: Soluble receptor for advanced glycation end products blocks hyperpermeability in diabetic rats

Journal of Clinical Investigation

Volumn 97, Issue 1, 1996, Pages 238-243

  Wautier, Jean Luc ^a,c   Zoukourian, Clotilde ^a   Chappey, Olivier ^a   Wautier, Marie Paule ^a   Guillausseau, Pierre Jean ^a   Cao, Rong ^b   Horl, Osamu ^b   Stern, David ^b   Schmidt, Ann Marie ^b  

^a UNIVERSITÉ PARIS DESCARTES   (France)

^b New York Presbyterian Columbia University Medical Center   (United States)

^c HÔPITAL LARIBOISIÈRE   (France)

Author keywords

Advanced glycation end product; Diabetes; Glycation; Immunoglobulin superfamily receptor; Permeability

Indexed keywords

CELL SURFACE RECEPTOR; GLYCOSYLATED PROTEIN;

ADULT; ANIMAL CELL; ARTICLE; BLOOD VESSEL PERMEABILITY; CONTROLLED STUDY; DIABETIC ANGIOPATHY; ENDOTHELIUM CELL; ERYTHROCYTE; HUMAN; HUMAN CELL; MALE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RECEPTOR BLOCKING;

ADULT; ALBUMINS; ANIMALS; ANTIOXIDANTS; CAPILLARY PERMEABILITY; CATTLE; CELLS, CULTURED; DIABETES MELLITUS; DIABETES MELLITUS, EXPERIMENTAL; ENDOTHELIUM, VASCULAR; ERYTHROCYTE TRANSFUSION; ERYTHROCYTES; GLYCOSYLATION END PRODUCTS, ADVANCED; HUMANS; INULIN; MIDDLE AGED; PROBUCOL; RATS; RECEPTORS, IMMUNOLOGIC; SOLUBILITY; VITAMIN E;

EID: 0030061699     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI118397     Document Type: Article

References (26)

1. Ruderman, N., J Williamson, and M Brownlee. 1992. Glucose and diabetic vascular disease. FASEB (Fed Am. Soc. Exp. Biol) J. 6:2905-2914.
2. Baynes, J. 1991. Role of oxidative stress in development of complications in diabetes. Diabetes. 40:405-412.
3. Brownlee, M., A. Cerami, and H. Vlassara. 1988. AGEs in tissue and the biochemical basis of diabetic complications. N. Engl. J. Med. 318:1315-1320.
4. Schmidt, A. M., O. Hon, J. Brett, S.-D. Yan, J. L. Wautier, and D. Stern. 1994. Cellular receptor for AGEs. Arterioscler. Thromb. 14:1521-1528.
5. Yang, Z., Z. Makita, Y. Horii, S. Brunelle, A. Cerami, P. Sehajpal, M. Suthanthiran, and H. Vlassara. 1991. Two novel rat liver membrane proteins that bind AGEs: relationship to macrophage receptor for glucose-modified proteins, J. Exp. Med 174.515-524.
6. Khoury, J , C Thomas, J. Loike, S. Hickman, L. Cao, and S. Silverstein. 1994. Macrophages adhere to glucose-modified basement membrane via their scavenger receptors J Biol Chem. 269:10197-10200
7. Biett J , A. M Schmidt, S D Yan, Y. S. Zou, E. Weidman, D. Pinsky, R Nowygrod, M. Keeper, C. Przysiecki, A. Shaw, et al, 1993. Survey of the distribution of a newly characterized receptor for AGEs in tissues. Am. J. Pathol. 143:1699-1712.
8. Ritthaler, U., N Roth, A. Bierhaus, R. Ziegler, A. M. Schmidt, R Waldherr, P Wahl, D Stern, and P. Nawroth 1995. Expression of RAGE in peripheral occlusive vascular disease Am. J Pathol 146:688-694.
9. Viberti, G. 1983 Increased capillary permeability in diabetes mellitus and its relationship to microvascular angiopathy. Am J Med 75:81-84.
10. Mattock, M., N Mornsh, G Viberti, H. Keen, A. Fitzgerald, and G. Jackson. 1992. Prospective study of microalbumnuria as predictor of mortality in NIDDM. Diabetes. 41:736-741
11. Yan, S. D., A M. Schmidt, G. M. Anderson, J Zhang, J Brett, Y. S. Zou, D Pinsky. and D. Stern 1994. Enhanced cellular oxidant stress by the interaction of advanced glycation endproducts with their receptors/binding proteins. J Biol. Chem 269:9889-9897.
12. Esposito, C., H. Gerlach, J. Brett, D. Stern, and H Vlassara. 1989. Endothehal receptor-mediated binding of glucose-modified albumin is associated with increased monolayer permeability and modulation of cell surface coagulant properties. J. Exp. Med 170:1387-1407.
13. Albelda S , P M. Sampson, F. R. Haselton, J. M. McNiff, S. N. Meller, S. K Williams, and A. P. Fishman 1988. Permeability characteristics of cultured endothelial cell monolayers. J. Appl Physiol. 64:308-322.
14. David, G , and R Reisfeld. 1974. Protein iodination with solid state lactoperoxidase. Biochemistry. 13:1014-1020.
15. Schmidt, A.-M., S.-D. Yan, J. Brett, R Mora, R. Nowygrod, and D. Stern. 1993. Regulation of human mononuclear phagocyte migration by cell surface binding proteins for advanced glycation end products. J. Clin. Invest 91. 2155-2168.
16. Williamson, J. R., K. Chang, R. G. Tilton, C. Prater, J. R. Jeffrey, C. Weigel, and W. R. Sherman. 1987. Increased vascular permeability in spontaneously diabetic BB/W rats and in rats with mild versus severe streptozotocin-induced diabetes. Diabetes. 36-813-821.
17. Wautier, J. L . M. P. Wautier, A. M. Schmidt, G. M. Anderson, O. Hori, C. Zoukourian, L Capron, O Chappey, J. Brett, P J. Guillausseau, and D Stern 1994. AGEs on the surface of diabetic erythrocytes bind to the vessel wall via a specific receptor inducing oxidant stress in the vasculature: a link between surface-associated AGEs and diabetic complications. Proc. Natl. Acad Sci. USA. 91:7742-7746
18. Schmidt, A M , M. Hasu, D. Popov, J. H. Zhang, J. Chen, S D. Yan, J. Brett, R. Cao, K. Kuwabara, G Costache, et al. 1994. The receptor for AGEs has a central role in vessel wall interactions and gene activation in response to circulating AGE-proteins. Proc. Natl. Acad. Sci USA. 91:8807-8811.
19. Wautier, J. L., C. Paton, M. P Wautier, D. Pintigny, E Abadie, P. Passa, and J. Caen. 1981. Increased adhesion of erythrocytes to endothelial cells in diabetes mellitus and its relation to vascular complications. N. Engl. J. Med. 305:237-242.
20. Shasby, D., and R Roberts. 1987. Transendothelial transfer of macromolecules in vitro Fed. Proc. 46:2506-2510.
21. Yaqoob, M. A. W. Patrick, P. McClelland, A. Stevenson, H. Mason, M. C White, and G. M. Bell. 1993. Relationship between markers of endothelial dysfunction, oxidant injury and tubular damage in patients with insulin-dependent diabetes mellitus. Clin. Sci. 85:557-562.
22. Vlassara, H., M. Brownlee, K. Manogue, C Dinarello, and A. Pasagian 1988. Cachectin/TNF and IL-1 induced by glucose-modified proteins: role in normal tissue remodeling Science (Wash. DC). 240:1546-1548.
23. Zatz, R., B Dunn, T. Meyer, S. Anderson, H. Rennke, and B. Brenner, 1986. Prevention of diabetic glomerulopathy by pharmacological amelioration of glomerular capillary hypertension. J Clin Invest. 77 1925-1930.
24. Parving, H , G. Viberti, H. Keen, J. Christiansen, and N. Lassen 1983. Hemodynamic factors in the genesis of diabetic microangiopathy. Metab. Clin Exp. 32:943-949.
25. Schmidt, A M., M. Vianna, M Gerlach, J. Brett, J. Ryan, J. Kao, C. Esposito, H. Hegarty, W Hurley, M Clauss, et al 1992 Isolation and characterization of binding proteins for advanced glycation endproducts from lung tissue which are present on the endothelial cell surface, J. Biol. Chem. 267:14987-14997.
26. Yamoaka, K., T. Nakagawa, and T. Uno. 1978. Application of Akaike's information criterion (AIC) in the evaluation of linear pharmacokinetic equations. J. Pharmacokinet Biopharm 6:165-175.