Synthesis and structure-activity relationships of novel 7-substituted 1,4-dihydro-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acids as antitumor agents. Part 1

Journal of Medicinal Chemistry

Volumn 45, Issue 25, 2002, Pages 5564-5575

  Tomita, Kyoji ^a   Tsuzuki, Yasunori ^a   Shibamori, Koh ichiro ^a   Tashima, Masanori ^a   Kajikawa, Fumie ^a   Sato, Yuji ^a   Kashimoto, Shigeki ^a   Chiba, Katsumi ^a   Hino, Katsuhiko ^a  

^a DAINIPPON SUMITOMO PHARMA CO LTD   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

1,4 DIHYDRO 4 OXO 1 (2 THIAZOLYL) 1,8 NAPHTHYRIDINE 3 CARBOXYLIC ACID; AMINE; ANTINEOPLASTIC AGENT; CARBOXYLIC ACID; CHEMICAL COMPOUND; NAPHTHYRIDINE DERIVATIVE; PYRROLIDINE DERIVATIVE; SULFIDE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CHEMICAL STRUCTURE; CYTOTOXICITY; PROTEIN MODIFICATION; STRUCTURE ACTIVITY RELATION; SYNTHESIS; TUMOR CELL LINE;

ANIMALS; ANTINEOPLASTIC AGENTS; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; MICE; NAPHTHYRIDINES; NEOPLASM TRANSPLANTATION; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; THIAZOLES; TUMOR CELLS, CULTURED;

EID: 0037028027     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm010057b     Document Type: Article

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